Tbc1d20 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tbc1d20
Entrez Gene ID	67231
Full Name	TBC1 domain family, member 20
Synonyms	1110028I04Rik,2810442O16Rik,AI414693,bs
General protein information	Preferred Names TBC1 domain family, member 20 Names TBC1 domain family member 20
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2\|2 G3

mRNA and Protein(s)

mRNA	Protein	Name
NM_024196.3	NP_077158.1	TBC1 domain family member 20
NM_024196.4	NP_077158.1	TBC1 domain family member 20

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	TBC1D20	XP_861927.2
Mus musculus (house mouse)	Tbc1d20	NP_077158.1
Rattus norvegicus (Norway rat)	Tbc1d20	NP_001004281.1
Caenorhabditis elegans (roundworm)	tbc-20	NP_497068.2
Xenopus tropicalis (tropical clawed frog)	tbc1d20.1	NP_001016881.1
Homo sapiens (human)	TBC1D20	NP_653229.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008312	XP_317154.4
Schizosaccharomyces pombe (fission yeast)	gyp10	NP_595501.1
Bos taurus (cattle)	TBC1D20	NP_001033118.1
Gallus gallus (chicken)	TBC1D20	XP_001235015.2
Danio rerio (zebrafish)	tbc1d20	NP_001020343.1
Neurospora crassa	NCU05272	XP_961909.1
Pan troglodytes (chimpanzee)	TBC1D20	XP_003316844.1
	TBC1D20	XP_001107845.1
Drosophila melanogaster (fruit fly)	CG17883	NP_001036448.1
Magnaporthe oryzae (rice blast fungus)	MGG_06021	XP_003711868.1

Gene Ontology
Bibliography

Related articles in PubMed

TBC1D20 mediates autophagy as a key regulator of autophagosome maturation.
Sidjanin DJ, Park AK, Ronchetti A, Martins J, Jackson WT
Autophagy12(10)1759-1775(2016 Oct)

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.
Fairfield H, Srivastava A, Ananda G, Liu R, Kircher M, Lakshminarayana A, Harris BS, Karst SY, Dionne LA, Kane CC, Curtain M, Berry ML, Ward-Bailey PF, Greenstein I, Byers C, Czechanski A, Sharp J, Palmer K, Gudis P, Martin W, Tadenev A, Bogdanik L, Pratt CH, Chang B, Schroeder DG, Cox GA, Cliften P, Milbrandt J, Murray S, Burgess R, Bergstrom DE, Donahue LR, Hamamy H, Masri A, Santoni FA, Makrythanasis P, Antonarakis SE, Shendure J, Reinholdt LG
Genome research25(7)948-57(2015 Jul)

Targeted disruption of Tbc1d20 with zinc-finger nucleases causes cataracts and testicular abnormalities in mice.
Park AK, Liegel RP, Ronchetti A, Ebert AD, Geurts A, Sidjanin DJ
BMC genetics15135(2014 Dec)

Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans.
Liegel RP, Handley MT, Ronchetti A, Brown S, Langemeyer L, Linford A, Chang B, Morris-Rosendahl DJ, Carpanini S, Posmyk R, Harthill V, Sheridan E, Abdel-Salam GM, Terhal PA, Faravelli F, Accorsi P, Giordano L, Pinelli L, Hartmann B, Ebert AD, Barr FA, Aligianis IA, Sidjanin DJ
American journal of human genetics93(6)1001-14(2013 Dec)

Gene expression study in the juvenile mouse testis: identification of stage-specific molecular pathways during spermatogenesis.
Clemente EJ, Furlong RA, Loveland KL, Affara NA
Mammalian genome : official journal of the International Mammalian Genome Society17(9)956-75(2006 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TBC1D20 has an essential role in the maturation of autophagosomes.
Title: TBC1D20 mediates autophagy as a key regulator of autophagosome maturation.

Disruption of Tbc1d20 in mice results in cataracts and aberrant acrosomal formation.
Title: Targeted disruption of Tbc1d20 with zinc-finger nucleases causes cataracts and testicular abnormalities in mice.

Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans.
Title: Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans.

The following Tbc1d20 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tbc1d20 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu19718	NM_024196.4 Latest version!	Mus musculus TBC1 domain family, member 20 (Tbc1d20), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OMu19718	NM_024196.3	Mus musculus TBC1 domain family, member 20 (Tbc1d20), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tbc1d20 ( NM_024196.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_077158.1 Mus musculus TBC1 domain family, member 20 (Tbc1d20), mRNA.

Price & Availability↑

CloneID	OMu19718
Clone ID Related Accession (Same CDS sequence)	NM_024196.3 , NM_024196.4
Accession Version	NM_024196.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1209bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-19
Organism	Mus musculus(house mouse)
Product	TBC1 domain family member 20
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL831735.10. On Apr 29, 2007 this sequence version replaced NM_024196.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK076124.1, AK168985.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCCCTCC GGCCCTCAAA GGGCGACGGC TCCGCCGGCC GCTGGGACCG CGGCGCAGGG 
AAGGCAGACT TTAATGCCAA AAGGAAAAAG AAGGTGGCAG AGATACACCA GGCTCTGAAC 
AGTGATCCCA TCGACTTGGC TGCCCTCCGA CGAATGGCTA TCAGTGAGGG AGGGCTCCTG 
ACTGATGAGA TCAGGTGCCA AGTATGGCCT AAGCTCCTCA ACGTGAACAC CAGTGAGCCA 
CCGCCTGTGT CAAGGAAGGA CCTTCGAGAC ATGAGCAAGG ACTACCAGCA AGTGCTGCTG 
GACGTCAGGC GATCTCTTCG GCGCTTCCCC CCTGGCATGC CGGACGAGCA GAGAGAAGGG 
CTCCAGGAAG AGCTAATCGA TATCATCCTC CTCGTCCTGG ATCGCAACCC TCAGCTCCAC 
TACTACCAGG GCTACCATGA CATCGTGGTC ACATTTCTGC TGGTGGTGGG GGAGAGGCTG 
GCAACATCCC TGGTAGAAAA ATTGTCTACC CACCACCTCA GGGATTTCAT GGATCCCACA 
ATGGACAACA CCAAGCACAT CCTAAATTAT CTGATGCCCA TCATTGACCA AGTGAGCCCA 
GAGCTCCACG ACTTCATGCA GAGTGCTGAG GTGGGGACCA TCTTTGCCCT CAGCTGGCTT 
ATCACCTGGT TTGGGCACGT CCTGATGGAC TTCAGGCACG TTGTGAGGTT ATACGACTTC 
TTCCTGGCCT GCCACCCACT TATGCCCATT TACTTTGCAG CTGTGATCGT GCTGTACCGG 
GAGCAGGAAG TCCTGGACTG TGACTGTGAC ATGGCCTCTG TCCACCACCT GTTGTCCCAG 
ATCCCTCAGG ACCTGCCCTA TGAGACGCTC ATCAGCAGAG CAGGAGACCT CTTTGTTCAG 
TTTCCCCCTT CTGAACTTGC AAGGGAGGCA GCTGCTCAGC AGGAGGCTGA GAGAACGGCA 
GCCTCTACTT TCAAAGACTT TGAGCTGGCA TCAACTCAGC AGAGGCCAGA CATGGTGCTG 
CGGCAGCGGT TTCGGGGACT TCTGAGGCCT GAGGCTCGAA CAAAAGATGT CCTGACCAAA 
CCAAGGACCA ACCGCTTTGT GAAACTGGCA GTGATGGGGC TGACGGTGGC CCTCGGAGCA 
GCAGCACTAG CAGTGGTGAA GAGCGCCCTG GAGTGGGCCC CTAAGTTCCA GCTGCAGCTG 
TTCCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_077158.1
CDS	103..1311
Translation	MALRPSKGDGSAGRWDRGAGKADFNAKRKKKVAEIHQALNSDPIDLAALRRMAISEGGLLTDEIRCQVWPKLLNVNTSEPPPVSRKDLRDMSKDYQQVLLDVRRSLRRFPPGMPDEQREGLQEELIDIILLVLDRNPQLHYYQGYHDIVVTFLLVVGERLATSLVEKLSTHHLRDFMDPTMDNTKHILNYLMPIIDQVSPELHDFMQSAEVGTIFALSWLITWFGHVLMDFRHVVRLYDFFLACHPLMPIYFAAVIVLYREQEVLDCDCDMASVHHLLSQIPQDLPYETLISRAGDLFVQFPPSELAREAAAQQEAERTAASTFKDFELASTQQRPDMVLRQRFRGLLRPEARTKDVLTKPRTNRFVKLAVMGLTVALGAAALAVVKSALEWAPKFQLQLFP

Target ORF information:

RefSeq Version	NM_024196.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus TBC1 domain family, member 20 (Tbc1d20), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024196.3

ORF Insert Sequence:

ATGGCCCTCC GGCCCTCAAA GGGCGACGGC TCCGCCGGCC GCTGGGACCG CGGCGCAGGG 
AAGGCAGACT TTAATGCCAA AAGGAAAAAG AAGGTGGCAG AGATACACCA GGCTCTGAAC 
AGTGATCCCA TCGACTTGGC TGCCCTCCGA CGAATGGCTA TCAGTGAGGG AGGGCTCCTG 
ACTGATGAGA TCAGGTGCCA AGTATGGCCT AAGCTCCTCA ACGTGAACAC CAGTGAGCCA 
CCGCCTGTGT CAAGGAAGGA CCTTCGAGAC ATGAGCAAGG ACTACCAGCA AGTGCTGCTG 
GACGTCAGGC GATCTCTTCG GCGCTTCCCC CCTGGCATGC CGGACGAGCA GAGAGAAGGG 
CTCCAGGAAG AGCTAATCGA TATCATCCTC CTCGTCCTGG ATCGCAACCC TCAGCTCCAC 
TACTACCAGG GCTACCATGA CATCGTGGTC ACATTTCTGC TGGTGGTGGG GGAGAGGCTG 
GCAACATCCC TGGTAGAAAA ATTGTCTACC CACCACCTCA GGGATTTCAT GGATCCCACA 
ATGGACAACA CCAAGCACAT CCTAAATTAT CTGATGCCCA TCATTGACCA AGTGAGCCCA 
GAGCTCCACG ACTTCATGCA GAGTGCTGAG GTGGGGACCA TCTTTGCCCT CAGCTGGCTT 
ATCACCTGGT TTGGGCACGT CCTGATGGAC TTCAGGCACG TTGTGAGGTT ATACGACTTC 
TTCCTGGCCT GCCACCCACT TATGCCCATT TACTTTGCAG CTGTGATCGT GCTGTACCGG 
GAGCAGGAAG TCCTGGACTG TGACTGTGAC ATGGCCTCTG TCCACCACCT GTTGTCCCAG 
ATCCCTCAGG ACCTGCCCTA TGAGACGCTC ATCAGCAGAG CAGGAGACCT CTTTGTTCAG 
TTTCCCCCTT CTGAACTTGC AAGGGAGGCA GCTGCTCAGC AGGAGGCTGA GAGAACGGCA 
GCCTCTACTT TCAAAGACTT TGAGCTGGCA TCAACTCAGC AGAGGCCAGA CATGGTGCTG 
CGGCAGCGGT TTCGGGGACT TCTGAGGCCT GAGGCTCGAA CAAAAGATGT CCTGACCAAA 
CCAAGGACCA ACCGCTTTGT GAAACTGGCA GTGATGGGGC TGACGGTGGC CCTCGGAGCA 
GCAGCACTAG CAGTGGTGAA GAGCGCCCTG GAGTGGGCCC CTAAGTTCCA GCTGCAGCTG 
TTCCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tbc1d20 ( NM_024196.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_077158.1 Mus musculus TBC1 domain family, member 20 (Tbc1d20), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu19718
Clone ID Related Accession (Same CDS sequence)	NM_024196.3 , NM_024196.4
Accession Version	NM_024196.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1209bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-23
Organism	Mus musculus(house mouse)
Product	TBC1 domain family member 20
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL831735.10. On Apr 25, 2018 this sequence version replaced NM_024196.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC086617.1, AK168985.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCTCC GGCCCTCAAA GGGCGACGGC TCCGCCGGCC GCTGGGACCG CGGCGCAGGG 
AAGGCAGACT TTAATGCCAA AAGGAAAAAG AAGGTGGCAG AGATACACCA GGCTCTGAAC 
AGTGATCCCA TCGACTTGGC TGCCCTCCGA CGAATGGCTA TCAGTGAGGG AGGGCTCCTG 
ACTGATGAGA TCAGGTGCCA AGTATGGCCT AAGCTCCTCA ACGTGAACAC CAGTGAGCCA 
CCGCCTGTGT CAAGGAAGGA CCTTCGAGAC ATGAGCAAGG ACTACCAGCA AGTGCTGCTG 
GACGTCAGGC GATCTCTTCG GCGCTTCCCC CCTGGCATGC CGGACGAGCA GAGAGAAGGG 
CTCCAGGAAG AGCTAATCGA TATCATCCTC CTCGTCCTGG ATCGCAACCC TCAGCTCCAC 
TACTACCAGG GCTACCATGA CATCGTGGTC ACATTTCTGC TGGTGGTGGG GGAGAGGCTG 
GCAACATCCC TGGTAGAAAA ATTGTCTACC CACCACCTCA GGGATTTCAT GGATCCCACA 
ATGGACAACA CCAAGCACAT CCTAAATTAT CTGATGCCCA TCATTGACCA AGTGAGCCCA 
GAGCTCCACG ACTTCATGCA GAGTGCTGAG GTGGGGACCA TCTTTGCCCT CAGCTGGCTT 
ATCACCTGGT TTGGGCACGT CCTGATGGAC TTCAGGCACG TTGTGAGGTT ATACGACTTC 
TTCCTGGCCT GCCACCCACT TATGCCCATT TACTTTGCAG CTGTGATCGT GCTGTACCGG 
GAGCAGGAAG TCCTGGACTG TGACTGTGAC ATGGCCTCTG TCCACCACCT GTTGTCCCAG 
ATCCCTCAGG ACCTGCCCTA TGAGACGCTC ATCAGCAGAG CAGGAGACCT CTTTGTTCAG 
TTTCCCCCTT CTGAACTTGC AAGGGAGGCA GCTGCTCAGC AGGAGGCTGA GAGAACGGCA 
GCCTCTACTT TCAAAGACTT TGAGCTGGCA TCAACTCAGC AGAGGCCAGA CATGGTGCTG 
CGGCAGCGGT TTCGGGGACT TCTGAGGCCT GAGGCTCGAA CAAAAGATGT CCTGACCAAA 
CCAAGGACCA ACCGCTTTGT GAAACTGGCA GTGATGGGGC TGACGGTGGC CCTCGGAGCA 
GCAGCACTAG CAGTGGTGAA GAGCGCCCTG GAGTGGGCCC CTAAGTTCCA GCTGCAGCTG 
TTCCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_077158.1
CDS	147..1355
Translation	MALRPSKGDGSAGRWDRGAGKADFNAKRKKKVAEIHQALNSDPIDLAALRRMAISEGGLLTDEIRCQVWPKLLNVNTSEPPPVSRKDLRDMSKDYQQVLLDVRRSLRRFPPGMPDEQREGLQEELIDIILLVLDRNPQLHYYQGYHDIVVTFLLVVGERLATSLVEKLSTHHLRDFMDPTMDNTKHILNYLMPIIDQVSPELHDFMQSAEVGTIFALSWLITWFGHVLMDFRHVVRLYDFFLACHPLMPIYFAAVIVLYREQEVLDCDCDMASVHHLLSQIPQDLPYETLISRAGDLFVQFPPSELAREAAAQQEAERTAASTFKDFELASTQQRPDMVLRQRFRGLLRPEARTKDVLTKPRTNRFVKLAVMGLTVALGAAALAVVKSALEWAPKFQLQLFP

Target ORF information:

RefSeq Version	NM_024196.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus TBC1 domain family, member 20 (Tbc1d20), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024196.4

ORF Insert Sequence:

ATGGCCCTCC GGCCCTCAAA GGGCGACGGC TCCGCCGGCC GCTGGGACCG CGGCGCAGGG 
AAGGCAGACT TTAATGCCAA AAGGAAAAAG AAGGTGGCAG AGATACACCA GGCTCTGAAC 
AGTGATCCCA TCGACTTGGC TGCCCTCCGA CGAATGGCTA TCAGTGAGGG AGGGCTCCTG 
ACTGATGAGA TCAGGTGCCA AGTATGGCCT AAGCTCCTCA ACGTGAACAC CAGTGAGCCA 
CCGCCTGTGT CAAGGAAGGA CCTTCGAGAC ATGAGCAAGG ACTACCAGCA AGTGCTGCTG 
GACGTCAGGC GATCTCTTCG GCGCTTCCCC CCTGGCATGC CGGACGAGCA GAGAGAAGGG 
CTCCAGGAAG AGCTAATCGA TATCATCCTC CTCGTCCTGG ATCGCAACCC TCAGCTCCAC 
TACTACCAGG GCTACCATGA CATCGTGGTC ACATTTCTGC TGGTGGTGGG GGAGAGGCTG 
GCAACATCCC TGGTAGAAAA ATTGTCTACC CACCACCTCA GGGATTTCAT GGATCCCACA 
ATGGACAACA CCAAGCACAT CCTAAATTAT CTGATGCCCA TCATTGACCA AGTGAGCCCA 
GAGCTCCACG ACTTCATGCA GAGTGCTGAG GTGGGGACCA TCTTTGCCCT CAGCTGGCTT 
ATCACCTGGT TTGGGCACGT CCTGATGGAC TTCAGGCACG TTGTGAGGTT ATACGACTTC 
TTCCTGGCCT GCCACCCACT TATGCCCATT TACTTTGCAG CTGTGATCGT GCTGTACCGG 
GAGCAGGAAG TCCTGGACTG TGACTGTGAC ATGGCCTCTG TCCACCACCT GTTGTCCCAG 
ATCCCTCAGG ACCTGCCCTA TGAGACGCTC ATCAGCAGAG CAGGAGACCT CTTTGTTCAG 
TTTCCCCCTT CTGAACTTGC AAGGGAGGCA GCTGCTCAGC AGGAGGCTGA GAGAACGGCA 
GCCTCTACTT TCAAAGACTT TGAGCTGGCA TCAACTCAGC AGAGGCCAGA CATGGTGCTG 
CGGCAGCGGT TTCGGGGACT TCTGAGGCCT GAGGCTCGAA CAAAAGATGT CCTGACCAAA 
CCAAGGACCA ACCGCTTTGT GAAACTGGCA GTGATGGGGC TGACGGTGGC CCTCGGAGCA 
GCAGCACTAG CAGTGGTGAA GAGCGCCCTG GAGTGGGCCC CTAAGTTCCA GCTGCAGCTG 
TTCCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

TBC1D20 mediates autophagy as a key regulator of autophagosome maturation.
Autophagy12(10)1759-1775(2016 Oct)
Sidjanin DJ,Park AK,Ronchetti A,Martins J,Jackson WT

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.
Genome research25(7)948-57(2015 Jul)
Fairfield H,Srivastava A,Ananda G,Liu R,Kircher M,Lakshminarayana A,Harris BS,Karst SY,Dionne LA,Kane CC,Curtain M,Berry ML,Ward-Bailey PF,Greenstein I,Byers C,Czechanski A,Sharp J,Palmer K,Gudis P,Martin W,Tadenev A,Bogdanik L,Pratt CH,Chang B,Schroeder DG,Cox GA,Cliften P,Milbrandt J,Murray S,Burgess R,Bergstrom DE,Donahue LR,Hamamy H,Masri A,Santoni FA,Makrythanasis P,Antonarakis SE,Shendure J,Reinholdt LG

Targeted disruption of Tbc1d20 with zinc-finger nucleases causes cataracts and testicular abnormalities in mice.
BMC genetics15135(2014 Dec)
Park AK,Liegel RP,Ronchetti A,Ebert AD,Geurts A,Sidjanin DJ

Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans.
American journal of human genetics93(6)1001-14(2013 Dec)
Liegel RP,Handley MT,Ronchetti A,Brown S,Langemeyer L,Linford A,Chang B,Morris-Rosendahl DJ,Carpanini S,Posmyk R,Harthill V,Sheridan E,Abdel-Salam GM,Terhal PA,Faravelli F,Accorsi P,Giordano L,Pinelli L,Hartmann B,Ebert AD,Barr FA,Aligianis IA,Sidjanin DJ

Gene expression study in the juvenile mouse testis: identification of stage-specific molecular pathways during spermatogenesis.
Mammalian genome : official journal of the International Mammalian Genome Society17(9)956-75(2006 Sep)
Clemente EJ,Furlong RA,Loveland KL,Affara NA

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Tbc1d20 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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