Fgf22 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fgf22
Entrez Gene ID	67112
Full Name	fibroblast growth factor 22
Synonyms	2210414E06Rik,FGF-22
General protein information	Preferred Names fibroblast growth factor 22 Names fibroblast growth factor 22
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 10 Map Location: 10\|10 C1

mRNA and Protein(s)

mRNA	Protein	Name
NM_023304.1	NP_075793.1	fibroblast growth factor 22 precursor
XM_030245228.1	XP_030101088.1	fibroblast growth factor 22 isoform X1
NM_023304.2	NP_075793.1	fibroblast growth factor 22 isoform 1 precursor
NM_001368662.1	NP_001355591.1	fibroblast growth factor 22 isoform 2 precursor
XM_006513973.2	XP_006514036.1	fibroblast growth factor 22 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	FGF22	NP_065688.1
Canis lupus familiaris (dog)	FGF22	XP_855230.2
	FGF22	XP_001091268.1
Bos taurus (cattle)	FGF22	NP_001192790.1
Rattus norvegicus (Norway rat)	Fgf22	NP_570107.1
Gallus gallus (chicken)	FGF22	XP_003642916.1
Mus musculus (house mouse)	Fgf22	NP_075793.1

Gene Ontology
Bibliography

Related articles in PubMed

Elimination of the male reproductive tract in the female embryo is promoted by COUP-TFII in mice.
Zhao F, Franco HL, Rodriguez KF, Brown PR, Tsai MJ, Tsai SY, Yao HH
Science (New York, N.Y.)357(6352)717-720(2017 08)

Selective Inactivation of Fibroblast Growth Factor 22 (FGF22) in CA3 Pyramidal Neurons Impairs Local Synaptogenesis and Affective Behavior Without Affecting Dentate Neurogenesis.
Terauchi A, Gavin E, Wilson J, Umemori H
Frontiers in synaptic neuroscience917(2017)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Deletion of fibroblast growth factor 22 (FGF22) causes a depression-like phenotype in adult mice.
Williams AJ, Yee P, Smith MC, Murphy GG, Umemori H
Behavioural brain research30711-7(2016 07)

Retrograde fibroblast growth factor 22 (FGF22) signaling regulates insulin-like growth factor 2 (IGF2) expression for activity-dependent synapse stabilization in the mammalian brain.
Terauchi A, Johnson-Venkatesh EM, Bullock B, Lehtinen MK, Umemori H
eLife5(2016 04)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Here the authors show that fibroblast growth factor 22 (FGF22), a target-derived presynaptic organizer in the mouse hippocampus, induces the expression of insulin-like growth factor 2 (IGF2) for the stabilization of presynaptic terminals.
Title: Retrograde fibroblast growth factor 22 (FGF22) signaling regulates insulin-like growth factor 2 (IGF2) expression for activity-dependent synapse stabilization in the mammalian brain.

FGF22 restores hearing loss after gentamycin treatment by maintaining ribbon synapse number, likely via inhibition of MEF2D.
Title: FGF22 protects hearing function from gentamycin ototoxicity by maintaining ribbon synapse number.

In FGF22 knock-out mice, presynaptically, the number of synaptic vesicles is reduced, along with bouton volume and reduced number of vesicles in axonal regions.
Title: Presynaptic size of associational/commissural CA3 synapses is controlled by fibroblast growth factor 22 in adult mice.

FGF22 is a synaptogenic mediator in the adult nervous system and a crucial regulator of synapse formation and maturation during post-injury remodeling in the spinal cord.
Title: FGF22 signaling regulates synapse formation during post-injury remodeling of the spinal cord.

we examine how the two presynaptic organizers FGF22 and FGF7 are transported to the appropriate locations so that they act as synapse-type-specific organizing molecules.
Title: Selective synaptic targeting of the excitatory and inhibitory presynaptic organizers FGF22 and FGF7.

The following Fgf22 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fgf22 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu44712	NM_001368662.1 Latest version!	Mus musculus fibroblast growth factor 22 (Fgf22), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu44712	XM_006513973.2 Latest version!	Mus musculus fibroblast growth factor 22 (Fgf22), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu19115	NM_023304.2 Latest version!	Mus musculus fibroblast growth factor 22 (Fgf22), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu85498	XM_030245228.1 Latest version!	Mus musculus fibroblast growth factor 22 (Fgf22), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu19115	NM_023304.1	Mus musculus fibroblast growth factor 22 (Fgf22), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fgf22 ( NM_001368662.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001355591.1 Mus musculus fibroblast growth factor 22 (Fgf22), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu44712
Clone ID Related Accession (Same CDS sequence)	NM_001368662.1 , XM_006513973.2
Accession Version	NM_001368662.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Mus musculus(house mouse)
Product	fibroblast growth factor 22 isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC119135.1 and AK008922.1. On Feb 15, 2019 this sequence version replaced XM_006513973.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK010054.1, BY709605.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849376 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 5' end.

ATGCGCAGCC GCCTCTGGCT GGGCCTAGCC TGGCTGCTGT TGGCGCGGGC ACCGGGCGCT 
CCGGGAGGGT ACCCGCATCT GGAGGGCGAC GTGCGCTGGC GCCGCCTCTT CTCCTCCACT 
CACTTTTTCC TGCGTGTGGA CCTTGGTGGT CGGGTGCAGG GGACGCGTTG GCGGCACGGC 
CAGGACAGTA TAGTGGAGAT CCGTTCTGTC CGTGTGGGCA CTGTGGTGAT CAAAGCTGTG 
TACTCAGGCT TCTATGTGGC CATGAATCGC AGGGGCCGCC TCTATGGGTC GGTTCCGGGA 
GCGCATCGAG GAGAACGGCT ACAACACATA CGCCTCGCGA CGTTGGAGGC ACCGCGGCCG 
ACCCATGTTC CTGGCACTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001355591.1
CDS	11..391
Translation	MRSRLWLGLAWLLLARAPGAPGGYPHLEGDVRWRRLFSSTHFFLRVDLGGRVQGTRWRHGQDSIVEIRSVRVGTVVIKAVYSGFYVAMNRRGRLYGSVPGAHRGERLQHIRLATLEAPRPTHVPGT

Target ORF information:

RefSeq Version	NM_001368662.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus fibroblast growth factor 22 (Fgf22), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001368662.1

ORF Insert Sequence:

ATGCGCAGCC GCCTCTGGCT GGGCCTAGCC TGGCTGCTGT TGGCGCGGGC ACCGGGCGCT 
CCGGGAGGGT ACCCGCATCT GGAGGGCGAC GTGCGCTGGC GCCGCCTCTT CTCCTCCACT 
CACTTTTTCC TGCGTGTGGA CCTTGGTGGT CGGGTGCAGG GGACGCGTTG GCGGCACGGC 
CAGGACAGTA TAGTGGAGAT CCGTTCTGTC CGTGTGGGCA CTGTGGTGAT CAAAGCTGTG 
TACTCAGGCT TCTATGTGGC CATGAATCGC AGGGGCCGCC TCTATGGGTC GGTTCCGGGA 
GCGCATCGAG GAGAACGGCT ACAACACATA CGCCTCGCGA CGTTGGAGGC ACCGCGGCCG 
ACCCATGTTC CTGGCACTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fgf22 ( XM_006513973.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006514036.1 Mus musculus fibroblast growth factor 22 (Fgf22), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu44712
Clone ID Related Accession (Same CDS sequence)	NM_001368662.1 , XM_006513973.2
Accession Version	XM_006513973.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	fibroblast growth factor 22 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006513973.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGCAGCC GCCTCTGGCT GGGCCTAGCC TGGCTGCTGT TGGCGCGGGC ACCGGGCGCT 
CCGGGAGGGT ACCCGCATCT GGAGGGCGAC GTGCGCTGGC GCCGCCTCTT CTCCTCCACT 
CACTTTTTCC TGCGTGTGGA CCTTGGTGGT CGGGTGCAGG GGACGCGTTG GCGGCACGGC 
CAGGACAGTA TAGTGGAGAT CCGTTCTGTC CGTGTGGGCA CTGTGGTGAT CAAAGCTGTG 
TACTCAGGCT TCTATGTGGC CATGAATCGC AGGGGCCGCC TCTATGGGTC GGTTCCGGGA 
GCGCATCGAG GAGAACGGCT ACAACACATA CGCCTCGCGA CGTTGGAGGC ACCGCGGCCG 
ACCCATGTTC CTGGCACTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006514036.1
CDS	545..925
Translation	MRSRLWLGLAWLLLARAPGAPGGYPHLEGDVRWRRLFSSTHFFLRVDLGGRVQGTRWRHGQDSIVEIRSVRVGTVVIKAVYSGFYVAMNRRGRLYGSVPGAHRGERLQHIRLATLEAPRPTHVPGT

Target ORF information:

RefSeq Version	XM_006513973.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus fibroblast growth factor 22 (Fgf22), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006513973.2

ORF Insert Sequence:

ATGCGCAGCC GCCTCTGGCT GGGCCTAGCC TGGCTGCTGT TGGCGCGGGC ACCGGGCGCT 
CCGGGAGGGT ACCCGCATCT GGAGGGCGAC GTGCGCTGGC GCCGCCTCTT CTCCTCCACT 
CACTTTTTCC TGCGTGTGGA CCTTGGTGGT CGGGTGCAGG GGACGCGTTG GCGGCACGGC 
CAGGACAGTA TAGTGGAGAT CCGTTCTGTC CGTGTGGGCA CTGTGGTGAT CAAAGCTGTG 
TACTCAGGCT TCTATGTGGC CATGAATCGC AGGGGCCGCC TCTATGGGTC GGTTCCGGGA 
GCGCATCGAG GAGAACGGCT ACAACACATA CGCCTCGCGA CGTTGGAGGC ACCGCGGCCG 
ACCCATGTTC CTGGCACTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fgf22 ( NM_023304.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_075793.1 Mus musculus fibroblast growth factor 22 (Fgf22), mRNA.

Price & Availability↑

CloneID	OMu19115
Clone ID Related Accession (Same CDS sequence)	NM_023304.1 , NM_023304.2
Accession Version	NM_023304.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 489bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-09-14
Organism	Mus musculus(house mouse)
Product	fibroblast growth factor 22 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB036765.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB036765.1, AK008922.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849376, SAMN00849384 [ECO:0000348] ##Evidence-Data-END##

ATGCGCAGCC GCCTCTGGCT GGGCCTAGCC TGGCTGCTGT TGGCGCGGGC ACCGGGCGCT 
CCGGGAGGGT ACCCGCATCT GGAGGGCGAC GTGCGCTGGC GCCGCCTCTT CTCCTCCACT 
CACTTTTTCC TGCGTGTGGA CCTTGGTGGT CGGGTGCAGG GGACGCGTTG GCGGCACGGC 
CAGGACAGTA TAGTGGAGAT CCGTTCTGTC CGTGTGGGCA CTGTGGTGAT CAAAGCTGTG 
TACTCAGGCT TCTATGTGGC CATGAATCGC AGGGGCCGCC TCTATGGGTC GCGGGTCTAC 
TCTGTGGACT GTAGGTTCCG GGAGCGCATC GAGGAGAACG GCTACAACAC ATACGCCTCG 
CGACGTTGGA GGCACCGCGG CCGACCCATG TTCCTGGCAC TTGACAGCCA AGGCATTCCC 
AGGCAAGGCA GACGGACACG ACGGCACCAA CTGTCCACAC ACTTCCTGCC AGTCTTGGTC 
TCGTCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_075793.1
CDS	1..489
Translation	MRSRLWLGLAWLLLARAPGAPGGYPHLEGDVRWRRLFSSTHFFLRVDLGGRVQGTRWRHGQDSIVEIRSVRVGTVVIKAVYSGFYVAMNRRGRLYGSRVYSVDCRFRERIEENGYNTYASRRWRHRGRPMFLALDSQGIPRQGRRTRRHQLSTHFLPVLVSS

Target ORF information:

RefSeq Version	NM_023304.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus fibroblast growth factor 22 (Fgf22), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_023304.1

ORF Insert Sequence:

ATGCGCAGCC GCCTCTGGCT GGGCCTAGCC TGGCTGCTGT TGGCGCGGGC ACCGGGCGCT 
CCGGGAGGGT ACCCGCATCT GGAGGGCGAC GTGCGCTGGC GCCGCCTCTT CTCCTCCACT 
CACTTTTTCC TGCGTGTGGA CCTTGGTGGT CGGGTGCAGG GGACGCGTTG GCGGCACGGC 
CAGGACAGTA TAGTGGAGAT CCGTTCTGTC CGTGTGGGCA CTGTGGTGAT CAAAGCTGTG 
TACTCAGGCT TCTATGTGGC CATGAATCGC AGGGGCCGCC TCTATGGGTC GCGGGTCTAC 
TCTGTGGACT GTAGGTTCCG GGAGCGCATC GAGGAGAACG GCTACAACAC ATACGCCTCG 
CGACGTTGGA GGCACCGCGG CCGACCCATG TTCCTGGCAC TTGACAGCCA AGGCATTCCC 
AGGCAAGGCA GACGGACACG ACGGCACCAA CTGTCCACAC ACTTCCTGCC AGTCTTGGTC 
TCGTCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fgf22 ( NM_023304.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_075793.1 Mus musculus fibroblast growth factor 22 (Fgf22), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu19115
Clone ID Related Accession (Same CDS sequence)	NM_023304.1 , NM_023304.2
Accession Version	NM_023304.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 489bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Mus musculus(house mouse)
Product	fibroblast growth factor 22 isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC151828.3 and AK008922.1. On Feb 14, 2019 this sequence version replaced NM_023304.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK008922.1, SRR7652917.946166.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849376, SAMN00849384 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 5' end.

ATGCGCAGCC GCCTCTGGCT GGGCCTAGCC TGGCTGCTGT TGGCGCGGGC ACCGGGCGCT 
CCGGGAGGGT ACCCGCATCT GGAGGGCGAC GTGCGCTGGC GCCGCCTCTT CTCCTCCACT 
CACTTTTTCC TGCGTGTGGA CCTTGGTGGT CGGGTGCAGG GGACGCGTTG GCGGCACGGC 
CAGGACAGTA TAGTGGAGAT CCGTTCTGTC CGTGTGGGCA CTGTGGTGAT CAAAGCTGTG 
TACTCAGGCT TCTATGTGGC CATGAATCGC AGGGGCCGCC TCTATGGGTC GCGGGTCTAC 
TCTGTGGACT GTAGGTTCCG GGAGCGCATC GAGGAGAACG GCTACAACAC ATACGCCTCG 
CGACGTTGGA GGCACCGCGG CCGACCCATG TTCCTGGCAC TTGACAGCCA AGGCATTCCC 
AGGCAAGGCA GACGGACACG ACGGCACCAA CTGTCCACAC ACTTCCTGCC AGTCTTGGTC 
TCGTCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_075793.1
CDS	11..499
Translation	MRSRLWLGLAWLLLARAPGAPGGYPHLEGDVRWRRLFSSTHFFLRVDLGGRVQGTRWRHGQDSIVEIRSVRVGTVVIKAVYSGFYVAMNRRGRLYGSRVYSVDCRFRERIEENGYNTYASRRWRHRGRPMFLALDSQGIPRQGRRTRRHQLSTHFLPVLVSS

Target ORF information:

RefSeq Version	NM_023304.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus fibroblast growth factor 22 (Fgf22), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_023304.2

ORF Insert Sequence:

ATGCGCAGCC GCCTCTGGCT GGGCCTAGCC TGGCTGCTGT TGGCGCGGGC ACCGGGCGCT 
CCGGGAGGGT ACCCGCATCT GGAGGGCGAC GTGCGCTGGC GCCGCCTCTT CTCCTCCACT 
CACTTTTTCC TGCGTGTGGA CCTTGGTGGT CGGGTGCAGG GGACGCGTTG GCGGCACGGC 
CAGGACAGTA TAGTGGAGAT CCGTTCTGTC CGTGTGGGCA CTGTGGTGAT CAAAGCTGTG 
TACTCAGGCT TCTATGTGGC CATGAATCGC AGGGGCCGCC TCTATGGGTC GCGGGTCTAC 
TCTGTGGACT GTAGGTTCCG GGAGCGCATC GAGGAGAACG GCTACAACAC ATACGCCTCG 
CGACGTTGGA GGCACCGCGG CCGACCCATG TTCCTGGCAC TTGACAGCCA AGGCATTCCC 
AGGCAAGGCA GACGGACACG ACGGCACCAA CTGTCCACAC ACTTCCTGCC AGTCTTGGTC 
TCGTCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fgf22 ( XM_030245228.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030101088.1 Mus musculus fibroblast growth factor 22 (Fgf22), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu85498
Clone ID Related Accession (Same CDS sequence)	XM_030245228.1
Accession Version	XM_030245228.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 789bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	fibroblast growth factor 22 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGCAGCC GCCTCTGGCT GGGCCTAGCC TGGCTGCTGT TGGCGCGGGC ACCGGGCGCT 
CCGGGAGGGT ACCCGCATCT GGAGGGCGAC GTGCGCTGGC GCCGCCTCTT CTCCTCCACT 
CACTTTTTCC TGCGTGTGGA CCTTGGTGGT CGGGTGCAGG GGACGCGTTG GCGGCACGGC 
CAGGACAGTA TAGTGGAGAT CCGTTCTGTC CGTGTGGGCA CTGTGGTGAT CAAAGCTGTG 
TACTCAGGCT TCTATGTGGC CATGAATCGC AGGGGCCGCC TCTATGGGTC GGTGAGTGAC 
TGGCGGTGGG CAGCTACTGG GTGGCAATGG TCAGTGGTGC AGACAGCCAG TCTCACGCAC 
CCGCCCTGCA GCGGGTCTAC TCTGTGGACT GTAGGTTCCG GGAGCGCATC GAGGAGAACG 
GCTACAACAC ATACGCCTCG CGACGTTGGA GGCACCGCGG CCGACCCATG TTCCTGGCAC 
TTGACAGCCA AGGCATTCCC AGGCAAGGCA GACGGACACG ACGGCACCAA CTGTCCACAC 
ACTTCCTGCC AGTCTTGGTC TCGTCTTGAA GGGCCTGCCA ATGGTTCAGG AGGCATGGGC 
GGCACACAGG GCCTGGAAGA TCCGGAGCTG AACAACCAAG GGCCAGGCCA GAGACCCTGG 
GCCAACACGA GTCTTTATGT CACAAGCCGG GCGCCCGCTG GCTGCCGGGC ATGGAGACAT 
GGCAGGGTCC CTGCAAGTGA AGCCAGCGCT CAGGGGGATA CACAGAACTG GCAGTTTGCA 
TCCATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030101088.1
CDS	69..857
Translation	MRSRLWLGLAWLLLARAPGAPGGYPHLEGDVRWRRLFSSTHFFLRVDLGGRVQGTRWRHGQDSIVEIRSVRVGTVVIKAVYSGFYVAMNRRGRLYGSVSDWRWAATGWQWSVVQTASLTHPPCSGSTLWTVGSGSASRRTATTHTPRDVGGTAADPCSWHLTAKAFPGKADGHDGTNCPHTSCQSWSRLEGPANGSGGMGGTQGLEDPELNNQGPGQRPWANTSLYVTSRAPAGCRAWRHGRVPASEASAQGDTQNWQFASI

Target ORF information:

RefSeq Version	XM_030245228.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus fibroblast growth factor 22 (Fgf22), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030245228.1

ORF Insert Sequence:

ATGCGCAGCC GCCTCTGGCT GGGCCTAGCC TGGCTGCTGT TGGCGCGGGC ACCGGGCGCT 
CCGGGAGGGT ACCCGCATCT GGAGGGCGAC GTGCGCTGGC GCCGCCTCTT CTCCTCCACT 
CACTTTTTCC TGCGTGTGGA CCTTGGTGGT CGGGTGCAGG GGACGCGTTG GCGGCACGGC 
CAGGACAGTA TAGTGGAGAT CCGTTCTGTC CGTGTGGGCA CTGTGGTGAT CAAAGCTGTG 
TACTCAGGCT TCTATGTGGC CATGAATCGC AGGGGCCGCC TCTATGGGTC GGTGAGTGAC 
TGGCGGTGGG CAGCTACTGG GTGGCAATGG TCAGTGGTGC AGACAGCCAG TCTCACGCAC 
CCGCCCTGCA GCGGGTCTAC TCTGTGGACT GTAGGTTCCG GGAGCGCATC GAGGAGAACG 
GCTACAACAC ATACGCCTCG CGACGTTGGA GGCACCGCGG CCGACCCATG TTCCTGGCAC 
TTGACAGCCA AGGCATTCCC AGGCAAGGCA GACGGACACG ACGGCACCAA CTGTCCACAC 
ACTTCCTGCC AGTCTTGGTC TCGTCTTGAA GGGCCTGCCA ATGGTTCAGG AGGCATGGGC 
GGCACACAGG GCCTGGAAGA TCCGGAGCTG AACAACCAAG GGCCAGGCCA GAGACCCTGG 
GCCAACACGA GTCTTTATGT CACAAGCCGG GCGCCCGCTG GCTGCCGGGC ATGGAGACAT 
GGCAGGGTCC CTGCAAGTGA AGCCAGCGCT CAGGGGGATA CACAGAACTG GCAGTTTGCA 
TCCATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Elimination of the male reproductive tract in the female embryo is promoted by COUP-TFII in mice.
Science (New York, N.Y.)357(6352)717-720(2017 08)
Zhao F,Franco HL,Rodriguez KF,Brown PR,Tsai MJ,Tsai SY,Yao HH

Selective Inactivation of Fibroblast Growth Factor 22 (FGF22) in CA3 Pyramidal Neurons Impairs Local Synaptogenesis and Affective Behavior Without Affecting Dentate Neurogenesis.
Frontiers in synaptic neuroscience917(2017)
Terauchi A,Gavin E,Wilson J,Umemori H

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Deletion of fibroblast growth factor 22 (FGF22) causes a depression-like phenotype in adult mice.
Behavioural brain research30711-7(2016 07)
Williams AJ,Yee P,Smith MC,Murphy GG,Umemori H

Retrograde fibroblast growth factor 22 (FGF22) signaling regulates insulin-like growth factor 2 (IGF2) expression for activity-dependent synapse stabilization in the mammalian brain.
eLife5(2016 04)
Terauchi A,Johnson-Venkatesh EM,Bullock B,Lehtinen MK,Umemori H

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Fgf22 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報