Tmem14c cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tmem14c
Entrez Gene ID	66154
Full Name	transmembrane protein 14C
Synonyms	1110021D01Rik,AU020193,HSPC194
General protein information	Preferred Names transmembrane protein 14C Names transmembrane protein 14C
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13\|13 A3.3

mRNA and Protein(s)

mRNA	Protein	Name
XM_006516938.3	XP_006517001.1	transmembrane protein 14C isoform X1
XM_006516939.2	XP_006517002.1	transmembrane protein 14C isoform X2
NM_001360770.1	NP_001347699.1	transmembrane protein 14C isoform 2
NM_025387.3	NP_079663.1	transmembrane protein 14C isoform 1
XM_006516937.2	XP_006517000.2	transmembrane protein 14C isoform X1
XM_006516937.3	XP_006517000.3	transmembrane protein 14C isoform X1

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	TMEM14C	XP_418940.1
Pan troglodytes (chimpanzee)	TMEM14C	XP_003950766.1
Rattus norvegicus (Norway rat)	Tmem14c	NP_001128641.1
Xenopus tropicalis (tropical clawed frog)	tmem14c	NP_001072424.1
	TMEM14C	XP_001087822.1
Canis lupus familiaris (dog)	TMEM14C	XP_535885.1
Homo sapiens (human)	TMEM14C	NP_001158730.1
Bos taurus (cattle)	TMEM14C	NP_001030514.1
Mus musculus (house mouse)	Tmem14c	NP_079663.1
Rattus norvegicus (Norway rat)	LOC100361993	XP_006250512.1
Danio rerio (zebrafish)	tmem14ca	NP_001038903.1

Gene Ontology
Bibliography

Related articles in PubMed

TMEM14C is required for erythroid mitochondrial heme metabolism.
Yien YY, Robledo RF, Schultz IJ, Takahashi-Makise N, Gwynn B, Bauer DE, Dass A, Yi G, Li L, Hildick-Smith GJ, Cooney JD, Pierce EL, Mohler K, Dailey TA, Miyata N, Kingsley PD, Garone C, Hattangadi SM, Huang H, Chen W, Keenan EM, Shah DI, Schlaeger TM, DiMauro S, Orkin SH, Cantor AB, Palis J, Koehler CM, Lodish HF, Kaplan J, Ward DM, Dailey HA, Phillips JD, Peters LL, Paw BH
The Journal of clinical investigation124(10)4294-304(2014 Oct)

Discovery of genes essential for heme biosynthesis through large-scale gene expression analysis.
Nilsson R, Schultz IJ, Pierce EL, Soltis KA, Naranuntarat A, Ward DM, Baughman JM, Paradkar PN, Kingsley PD, Culotta VC, Kaplan J, Palis J, Paw BH, Mootha VK
Cell metabolism10(2)119-30(2009 Aug)

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES, Mann M
Cell115(5)629-40(2003 Nov)

Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia.
Carninci P, Waki K, Shiraki T, Konno H, Shibata K, Itoh M, Aizawa K, Arakawa T, Ishii Y, Sasaki D, Bono H, Kondo S, Sugahara Y, Saito R, Osato N, Fukuda S, Sato K, Watahiki A, Hirozane-Kishikawa T, Nakamura M, Shibata Y, Yasunishi A, Kikuchi N, Yoshiki A, Kusakabe M, Gustincich S, Beisel K, Pavan W, Aidinis V, Nakagawara A, Held WA, Iwata H, Kono T, Nakauchi H, Lyons P, Wells C, Hume DA, Fagiolini M, Hensch TK, Brinkmeier M, Camper S, Hirota J, Mombaerts P, Muramatsu M, Okazaki Y, Kawai J, Hayashizaki Y
Genome research13(6B)1273-89(2003 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TMEM14C facilitates the import of protoporphyrinogen IX into the mitochondrial matrix for heme synthesis and subsequent hemoglobin production
Title: TMEM14C is required for erythroid mitochondrial heme metabolism.

Required for functional heme biosynthesis in erythroid cells.
Title: Discovery of genes essential for heme biosynthesis through large-scale gene expression analysis.

The following Tmem14c gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tmem14c cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu48556	NM_001360770.1 Latest version!	Mus musculus transmembrane protein 14C (Tmem14c), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu48556	XM_006516939.2 Latest version!	Mus musculus transmembrane protein 14C (Tmem14c), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu48556	XM_006516938.3 Latest version!	Mus musculus transmembrane protein 14C (Tmem14c), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu69897	XM_006516937.2 Latest version!	Mus musculus transmembrane protein 14C (Tmem14c), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu00383	NM_025387.3 Latest version!	Mus musculus transmembrane protein 14C (Tmem14c), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu48556	XM_006516937.3 Latest version!	Mus musculus transmembrane protein 14C (Tmem14c), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tmem14c ( NM_001360770.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001347699.1 Mus musculus transmembrane protein 14C (Tmem14c), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu48556
Clone ID Related Accession (Same CDS sequence)	XM_006516938.3 , XM_006516939.2 , NM_001360770.1 , XM_006516937.3
Accession Version	NM_001360770.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 321bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-23
Organism	Mus musculus(house mouse)
Product	transmembrane protein 14C isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC133496.3. On Feb 13, 2018 this sequence version replaced XM_006516939.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BG969592.1, AK008495.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTTTAC ATTATTTTGG TTTCGGCTAT GCAGCCCTGG TTGCTACCGG TGGGATTATT 
GGCTATGCCA AAGCAGGTAG TGTGCCGTCC CTGGCTGCTG GACTCTTCTT CGGGGGCCTG 
GCAGGCCTGG GGGCCTACCA GCTGTCTCAG GATCCCAGGA ATGTGTGGGT TTTCCTAGCT 
ACATCTGGGA CCTTGGCCGG AATTATGGGG ATGAGATTCT ACAACTCGGG GAAATTTATG 
CCTGCAGGGT TAATCGCAGG AGCCAGTTTG CTGATGGTTG CCAAAGTTGG AATTAGTCTG 
TTGAGTTCAC CTCATCCGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001347699.1
CDS	151..471
Translation	MPLHYFGFGYAALVATGGIIGYAKAGSVPSLAAGLFFGGLAGLGAYQLSQDPRNVWVFLATSGTLAGIMGMRFYNSGKFMPAGLIAGASLLMVAKVGISLLSSPHP

Target ORF information:

RefSeq Version	NM_001360770.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus transmembrane protein 14C (Tmem14c), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001360770.1

ORF Insert Sequence:

ATGCCTTTAC ATTATTTTGG TTTCGGCTAT GCAGCCCTGG TTGCTACCGG TGGGATTATT 
GGCTATGCCA AAGCAGGTAG TGTGCCGTCC CTGGCTGCTG GACTCTTCTT CGGGGGCCTG 
GCAGGCCTGG GGGCCTACCA GCTGTCTCAG GATCCCAGGA ATGTGTGGGT TTTCCTAGCT 
ACATCTGGGA CCTTGGCCGG AATTATGGGG ATGAGATTCT ACAACTCGGG GAAATTTATG 
CCTGCAGGGT TAATCGCAGG AGCCAGTTTG CTGATGGTTG CCAAAGTTGG AATTAGTCTG 
TTGAGTTCAC CTCATCCGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tmem14c ( XM_006516938.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006517001.1 Mus musculus transmembrane protein 14C (Tmem14c), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu48556
Clone ID Related Accession (Same CDS sequence)	XM_006516938.3 , XM_006516939.2 , NM_001360770.1 , XM_006516937.3
Accession Version	XM_006516938.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 321bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	transmembrane protein 14C isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006516938.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTTTAC ATTATTTTGG TTTCGGCTAT GCAGCCCTGG TTGCTACCGG TGGGATTATT 
GGCTATGCCA AAGCAGGTAG TGTGCCGTCC CTGGCTGCTG GACTCTTCTT CGGGGGCCTG 
GCAGGCCTGG GGGCCTACCA GCTGTCTCAG GATCCCAGGA ATGTGTGGGT TTTCCTAGCT 
ACATCTGGGA CCTTGGCCGG AATTATGGGG ATGAGATTCT ACAACTCGGG GAAATTTATG 
CCTGCAGGGT TAATCGCAGG AGCCAGTTTG CTGATGGTTG CCAAAGTTGG AATTAGTCTG 
TTGAGTTCAC CTCATCCGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006517001.1
CDS	299..619
Translation	MPLHYFGFGYAALVATGGIIGYAKAGSVPSLAAGLFFGGLAGLGAYQLSQDPRNVWVFLATSGTLAGIMGMRFYNSGKFMPAGLIAGASLLMVAKVGISLLSSPHP

Target ORF information:

RefSeq Version	XM_006516938.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus transmembrane protein 14C (Tmem14c), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006516938.3

ORF Insert Sequence:

ATGCCTTTAC ATTATTTTGG TTTCGGCTAT GCAGCCCTGG TTGCTACCGG TGGGATTATT 
GGCTATGCCA AAGCAGGTAG TGTGCCGTCC CTGGCTGCTG GACTCTTCTT CGGGGGCCTG 
GCAGGCCTGG GGGCCTACCA GCTGTCTCAG GATCCCAGGA ATGTGTGGGT TTTCCTAGCT 
ACATCTGGGA CCTTGGCCGG AATTATGGGG ATGAGATTCT ACAACTCGGG GAAATTTATG 
CCTGCAGGGT TAATCGCAGG AGCCAGTTTG CTGATGGTTG CCAAAGTTGG AATTAGTCTG 
TTGAGTTCAC CTCATCCGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tmem14c ( XM_006516939.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006517002.1 Mus musculus transmembrane protein 14C (Tmem14c), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu48556
Clone ID Related Accession (Same CDS sequence)	XM_006516938.3 , XM_006516939.2 , NM_001360770.1 , XM_006516937.3
Accession Version	XM_006516939.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 321bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	transmembrane protein 14C isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006516939.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTTTAC ATTATTTTGG TTTCGGCTAT GCAGCCCTGG TTGCTACCGG TGGGATTATT 
GGCTATGCCA AAGCAGGTAG TGTGCCGTCC CTGGCTGCTG GACTCTTCTT CGGGGGCCTG 
GCAGGCCTGG GGGCCTACCA GCTGTCTCAG GATCCCAGGA ATGTGTGGGT TTTCCTAGCT 
ACATCTGGGA CCTTGGCCGG AATTATGGGG ATGAGATTCT ACAACTCGGG GAAATTTATG 
CCTGCAGGGT TAATCGCAGG AGCCAGTTTG CTGATGGTTG CCAAAGTTGG AATTAGTCTG 
TTGAGTTCAC CTCATCCGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006517002.1
CDS	145..465
Translation	MPLHYFGFGYAALVATGGIIGYAKAGSVPSLAAGLFFGGLAGLGAYQLSQDPRNVWVFLATSGTLAGIMGMRFYNSGKFMPAGLIAGASLLMVAKVGISLLSSPHP

Target ORF information:

RefSeq Version	XM_006516939.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus transmembrane protein 14C (Tmem14c), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006516939.2

ORF Insert Sequence:

ATGCCTTTAC ATTATTTTGG TTTCGGCTAT GCAGCCCTGG TTGCTACCGG TGGGATTATT 
GGCTATGCCA AAGCAGGTAG TGTGCCGTCC CTGGCTGCTG GACTCTTCTT CGGGGGCCTG 
GCAGGCCTGG GGGCCTACCA GCTGTCTCAG GATCCCAGGA ATGTGTGGGT TTTCCTAGCT 
ACATCTGGGA CCTTGGCCGG AATTATGGGG ATGAGATTCT ACAACTCGGG GAAATTTATG 
CCTGCAGGGT TAATCGCAGG AGCCAGTTTG CTGATGGTTG CCAAAGTTGG AATTAGTCTG 
TTGAGTTCAC CTCATCCGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tmem14c ( XM_006516937.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006517000.2 Mus musculus transmembrane protein 14C (Tmem14c), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu69897
Clone ID Related Accession (Same CDS sequence)	XM_006516937.2
Accession Version	XM_006516937.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 594bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	transmembrane protein 14C isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006516937.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATCCTTG AACTAGCGGC CTGGGACATG GACTTGAATC CAGTTCTGCC ACTGGCTAGT 
TCTTTCACCG AGCCTGCCAC CTGGCCTATC TTTCTTTCTG ATTGGGCACT GGCAGAATTT 
GCTGGAAACG ACAATCCTTT TGTCCCTGAG GATGATTTAA GCAATTACAT TTACTTCTTT 
GTGTGGATGC ATTCGTGCCA TGTTGAGTTT GTAGGTGTCA GAGGACAATT TTCAGGAGTT 
GCGGGAGTTG ATCTTCTGCT ATGTGGACCA TTGATGCCTT TACATTATTT TGGTTTCGGC 
TATGCAGCCC TGGTTGCTAC CGGTGGGATT ATTGGCTATG CCAAAGCAGG TAGTGTGCCG 
TCCCTGGCTG CTGGACTCTT CTTCGGGGGC CTGGCAGGCC TGGGGGCCTA CCAGCTGTCT 
CAGGATCCCA GGAATGTGTG GGTTTTCCTA GCTACATCTG GGACCTTGGC CGGAATTATG 
GGGATGAGAT TCTACAACTC GGGGAAATTT ATGCCTGCAG GGTTAATCGC AGGAGCCAGT 
TTGCTGATGG TTGCCAAAGT TGGAATTAGT CTGTTGAGTT CACCTCATCC GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006517000.2
CDS	7..600
Translation	MILELAAWDMDLNPVLPLASSFTEPATWPIFLSDWALAEFAGNDNPFVPEDDLSNYIYFFVWMHSCHVEFVGVRGQFSGVAGVDLLLCGPLMPLHYFGFGYAALVATGGIIGYAKAGSVPSLAAGLFFGGLAGLGAYQLSQDPRNVWVFLATSGTLAGIMGMRFYNSGKFMPAGLIAGASLLMVAKVGISLLSSPHP

Target ORF information:

RefSeq Version	XM_006516937.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus transmembrane protein 14C (Tmem14c), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006516937.2

ORF Insert Sequence:

ATGATCCTTG AACTAGCGGC CTGGGACATG GACTTGAATC CAGTTCTGCC ACTGGCTAGT 
TCTTTCACCG AGCCTGCCAC CTGGCCTATC TTTCTTTCTG ATTGGGCACT GGCAGAATTT 
GCTGGAAACG ACAATCCTTT TGTCCCTGAG GATGATTTAA GCAATTACAT TTACTTCTTT 
GTGTGGATGC ATTCGTGCCA TGTTGAGTTT GTAGGTGTCA GAGGACAATT TTCAGGAGTT 
GCGGGAGTTG ATCTTCTGCT ATGTGGACCA TTGATGCCTT TACATTATTT TGGTTTCGGC 
TATGCAGCCC TGGTTGCTAC CGGTGGGATT ATTGGCTATG CCAAAGCAGG TAGTGTGCCG 
TCCCTGGCTG CTGGACTCTT CTTCGGGGGC CTGGCAGGCC TGGGGGCCTA CCAGCTGTCT 
CAGGATCCCA GGAATGTGTG GGTTTTCCTA GCTACATCTG GGACCTTGGC CGGAATTATG 
GGGATGAGAT TCTACAACTC GGGGAAATTT ATGCCTGCAG GGTTAATCGC AGGAGCCAGT 
TTGCTGATGG TTGCCAAAGT TGGAATTAGT CTGTTGAGTT CACCTCATCC GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tmem14c ( NM_025387.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_079663.1 Mus musculus transmembrane protein 14C (Tmem14c), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu00383
Clone ID Related Accession (Same CDS sequence)	NM_025387.3
Accession Version	NM_025387.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 345bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Mus musculus(house mouse)
Product	transmembrane protein 14C isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY785978.1, AK010609.1 and CO039120.1. On Mar 11, 2009 this sequence version replaced NM_025387.2. ##Evidence-Data-START## Transcript exon combination :: BC025854.1, AK010609.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGAAAG ACAGTGGCCC ATTGATGCCT TTACATTATT TTGGTTTCGG CTATGCAGCC 
CTGGTTGCTA CCGGTGGGAT TATTGGCTAT GCCAAAGCAG GTAGTGTGCC GTCCCTGGCT 
GCTGGACTCT TCTTCGGGGG CCTGGCAGGC CTGGGGGCCT ACCAGCTGTC TCAGGATCCC 
AGGAATGTGT GGGTTTTCCT AGCTACATCT GGGACCTTGG CCGGAATTAT GGGGATGAGA 
TTCTACAACT CGGGGAAATT TATGCCTGCA GGGTTAATCG CAGGAGCCAG TTTGCTGATG 
GTTGCCAAAG TTGGAATTAG TCTGTTGAGT TCACCTCATC CGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079663.1
CDS	186..530
Translation	MQKDSGPLMPLHYFGFGYAALVATGGIIGYAKAGSVPSLAAGLFFGGLAGLGAYQLSQDPRNVWVFLATSGTLAGIMGMRFYNSGKFMPAGLIAGASLLMVAKVGISLLSSPHP

Target ORF information:

RefSeq Version	NM_025387.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus transmembrane protein 14C (Tmem14c), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025387.3

ORF Insert Sequence:

ATGCAGAAAG ACAGTGGCCC ATTGATGCCT TTACATTATT TTGGTTTCGG CTATGCAGCC 
CTGGTTGCTA CCGGTGGGAT TATTGGCTAT GCCAAAGCAG GTAGTGTGCC GTCCCTGGCT 
GCTGGACTCT TCTTCGGGGG CCTGGCAGGC CTGGGGGCCT ACCAGCTGTC TCAGGATCCC 
AGGAATGTGT GGGTTTTCCT AGCTACATCT GGGACCTTGG CCGGAATTAT GGGGATGAGA 
TTCTACAACT CGGGGAAATT TATGCCTGCA GGGTTAATCG CAGGAGCCAG TTTGCTGATG 
GTTGCCAAAG TTGGAATTAG TCTGTTGAGT TCACCTCATC CGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tmem14c ( XM_006516937.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006517000.3 Mus musculus transmembrane protein 14C (Tmem14c), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu48556
Clone ID Related Accession (Same CDS sequence)	XM_006516938.3 , XM_006516939.2 , NM_001360770.1 , XM_006516937.3
Accession Version	XM_006516937.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 321bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	transmembrane protein 14C isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006516937.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTTTAC ATTATTTTGG TTTCGGCTAT GCAGCCCTGG TTGCTACCGG TGGGATTATT 
GGCTATGCCA AAGCAGGTAG TGTGCCGTCC CTGGCTGCTG GACTCTTCTT CGGGGGCCTG 
GCAGGCCTGG GGGCCTACCA GCTGTCTCAG GATCCCAGGA ATGTGTGGGT TTTCCTAGCT 
ACATCTGGGA CCTTGGCCGG AATTATGGGG ATGAGATTCT ACAACTCGGG GAAATTTATG 
CCTGCAGGGT TAATCGCAGG AGCCAGTTTG CTGATGGTTG CCAAAGTTGG AATTAGTCTG 
TTGAGTTCAC CTCATCCGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006517000.3
CDS	21..341
Translation	MPLHYFGFGYAALVATGGIIGYAKAGSVPSLAAGLFFGGLAGLGAYQLSQDPRNVWVFLATSGTLAGIMGMRFYNSGKFMPAGLIAGASLLMVAKVGISLLSSPHP

Target ORF information:

RefSeq Version	XM_006516937.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus transmembrane protein 14C (Tmem14c), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006516937.3

ORF Insert Sequence:

ATGCCTTTAC ATTATTTTGG TTTCGGCTAT GCAGCCCTGG TTGCTACCGG TGGGATTATT 
GGCTATGCCA AAGCAGGTAG TGTGCCGTCC CTGGCTGCTG GACTCTTCTT CGGGGGCCTG 
GCAGGCCTGG GGGCCTACCA GCTGTCTCAG GATCCCAGGA ATGTGTGGGT TTTCCTAGCT 
ACATCTGGGA CCTTGGCCGG AATTATGGGG ATGAGATTCT ACAACTCGGG GAAATTTATG 
CCTGCAGGGT TAATCGCAGG AGCCAGTTTG CTGATGGTTG CCAAAGTTGG AATTAGTCTG 
TTGAGTTCAC CTCATCCGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

TMEM14C is required for erythroid mitochondrial heme metabolism.
The Journal of clinical investigation124(10)4294-304(2014 Oct)
Yien YY,Robledo RF,Schultz IJ,Takahashi-Makise N,Gwynn B,Bauer DE,Dass A,Yi G,Li L,Hildick-Smith GJ,Cooney JD,Pierce EL,Mohler K,Dailey TA,Miyata N,Kingsley PD,Garone C,Hattangadi SM,Huang H,Chen W,Keenan EM,Shah DI,Schlaeger TM,DiMauro S,Orkin SH,Cantor AB,Palis J,Koehler CM,Lodish HF,Kaplan J,Ward DM,Dailey HA,Phillips JD,Peters LL,Paw BH

Discovery of genes essential for heme biosynthesis through large-scale gene expression analysis.
Cell metabolism10(2)119-30(2009 Aug)
Nilsson R,Schultz IJ,Pierce EL,Soltis KA,Naranuntarat A,Ward DM,Baughman JM,Paradkar PN,Kingsley PD,Culotta VC,Kaplan J,Palis J,Paw BH,Mootha VK

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Cell115(5)629-40(2003 Nov)
Mootha VK,Bunkenborg J,Olsen JV,Hjerrild M,Wisniewski JR,Stahl E,Bolouri MS,Ray HN,Sihag S,Kamal M,Patterson N,Lander ES,Mann M

Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia.
Genome research13(6B)1273-89(2003 Jun)
Carninci P,Waki K,Shiraki T,Konno H,Shibata K,Itoh M,Aizawa K,Arakawa T,Ishii Y,Sasaki D,Bono H,Kondo S,Sugahara Y,Saito R,Osato N,Fukuda S,Sato K,Watahiki A,Hirozane-Kishikawa T,Nakamura M,Shibata Y,Yasunishi A,Kikuchi N,Yoshiki A,Kusakabe M,Gustincich S,Beisel K,Pavan W,Aidinis V,Nakagawara A,Held WA,Iwata H,Kono T,Nakauchi H,Lyons P,Wells C,Hume DA,Fagiolini M,Hensch TK,Brinkmeier M,Camper S,Hirota J,Mombaerts P,Muramatsu M,Okazaki Y,Kawai J,Hayashizaki Y

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Tmem14c cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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