Angptl7 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Angptl7
Entrez Gene ID	654812
Full Name	angiopoietin-like 7
General protein information	Preferred Names angiopoietin-like 7 Names angiopoietin-related protein 7 angiopoietin-like protein 7
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4\|4 E2

mRNA and Protein(s)

mRNA	Protein	Name
XM_006539091.3	XP_006539154.1	angiopoietin-related protein 7 isoform X1
NM_001039554.3	NP_001034643.1	angiopoietin-related protein 7 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	ANGPTL7	NP_066969.1
	ANGPTL7	XP_001103825.1
Bos taurus (cattle)	ANGPTL7	NP_001014909.1
Gallus gallus (chicken)	ANGPTL7	XP_004947524.1
Xenopus tropicalis (tropical clawed frog)	angptl7	NP_001096248.1
Canis lupus familiaris (dog)	ANGPTL7	XP_852356.1
Mus musculus (house mouse)	Angptl7	NP_001034643.1
Pan troglodytes (chimpanzee)	ANGPTL7	XP_001137075.1
Rattus norvegicus (Norway rat)	LOC102552055	XP_006239486.1
Danio rerio (zebrafish)	angptl7	NP_001006073.1

Gene Ontology
Bibliography

Related articles in PubMed

Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury.
Wu Y, Wei FY, Kawarada L, Suzuki T, Araki K, Komohara Y, Fujimura A, Kaitsuka T, Takeya M, Oike Y, Suzuki T, Tomizawa K
PLoS genetics12(9)e1006355(2016 Sep)

Angiopoietin-Like Protein 7 Promotes an Inflammatory Phenotype in RAW264.7 Macrophages Through the P38 MAPK Signaling Pathway.
Qian T, Wang K, Cui J, He Y, Yang Z
Inflammation39(3)974-85(2016 Jun)

Loss of Angiopoietin-like 7 diminishes the regeneration capacity of hematopoietic stem and progenitor cells.
Xiao Y, Wei X, Jiang Z, Wang X, Ye W, Liu X, Zhang M, Xu Y, Wu D, Lai L, Yao H, Liu Z, Cao S, Liu P, Xu B, Li Y, Yao Y, Pei D, Li P
Journal of hematology & oncology87(2015 Feb)

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A, Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR
Neuron83(2)309-323(2014 Jul)

A mouse knockout library for secreted and transmembrane proteins.
Tang T, Li L, Tang J, Li Y, Lin WY, Martin F, Grant D, Solloway M, Parker L, Ye W, Forrest W, Ghilardi N, Oravecz T, Platt KA, Rice DS, Hansen GM, Abuin A, Eberhart DE, Godowski P, Holt KH, Peterson A, Zambrowicz BP, de Sauvage FJ
Nature biotechnology28(7)749-55(2010 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Angptl7 is a factor that promotes pro-inflammatory responses in macrophages through the P38 MAPK signaling pathway
Title: Angiopoietin-Like Protein 7 Promotes an Inflammatory Phenotype in RAW264.7 Macrophages Through the P38 MAPK Signaling Pathway.

Angptl7 was indispensable for bone marrow microenvironment to support hematopoietic stem cells repopulation
Title: Loss of Angiopoietin-like 7 diminishes the regeneration capacity of hematopoietic stem and progenitor cells.

The following Angptl7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Angptl7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu34373	XM_006539091.3 Latest version!	Mus musculus angiopoietin-like 7 (Angptl7), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu00714	NM_001039554.3 Latest version!	Mus musculus angiopoietin-like 7 (Angptl7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Angptl7 ( XM_006539091.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006539154.1 Mus musculus angiopoietin-like 7 (Angptl7), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu34373
Clone ID Related Accession (Same CDS sequence)	XM_006539091.3
Accession Version	XM_006539091.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 552bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	angiopoietin-related protein 7 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006539091.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAACTT CAGGAGGAGG CTGGACCATC ATCCAGAGAC GTAAGAGTGG CCTTGTCTCC 
TTCTACCAAG ACTGGAGACA GTATAAGCAA GGGTTTGGCA GCATCCGAGG TGACTTCTGG 
CTGGGGAATG AACATATCCA CCGGCTCACC AGGCAGCCAA GCCGGCTTCG TGTGGAGCTG 
GAGGACTGGG AGGGCAATGC ACGCTACGCA GAGTATAGCT ACTTTGCGTT GGGCAATGAA 
CTGAACAGCT ACCGCCTCTT CCTGGGGAAC TACAGTGGCA ACGTGGGGAA GGACGCCCTC 
CTCTACCATA ACAACACCGT CTTCAGCACC AAGGACAAGG ACAACGACAA CTGCTTGGAC 
AAGTGCGCAC AGCTCCGAAA AGGTGGCTAC TGGTACAACT GCTGCACAGA CTCCAACCTC 
AATGGGGTGT ACTACCGCCT TGGCGAGCAC CGAAAGCACA TGGATGGCAT CAGCTGGTAT 
GGCTGGCATG GAGCCAACTA TTCCCTCAAA CGTGTGGAAA TGAAGATCCG CCCAGAAGCC 
TTCAAGCCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006539154.1
CDS	526..1077
Translation	METSGGGWTIIQRRKSGLVSFYQDWRQYKQGFGSIRGDFWLGNEHIHRLTRQPSRLRVELEDWEGNARYAEYSYFALGNELNSYRLFLGNYSGNVGKDALLYHNNTVFSTKDKDNDNCLDKCAQLRKGGYWYNCCTDSNLNGVYYRLGEHRKHMDGISWYGWHGANYSLKRVEMKIRPEAFKP

Target ORF information:

RefSeq Version	XM_006539091.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus angiopoietin-like 7 (Angptl7), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006539091.3

ORF Insert Sequence:

ATGGAAACTT CAGGAGGAGG CTGGACCATC ATCCAGAGAC GTAAGAGTGG CCTTGTCTCC 
TTCTACCAAG ACTGGAGACA GTATAAGCAA GGGTTTGGCA GCATCCGAGG TGACTTCTGG 
CTGGGGAATG AACATATCCA CCGGCTCACC AGGCAGCCAA GCCGGCTTCG TGTGGAGCTG 
GAGGACTGGG AGGGCAATGC ACGCTACGCA GAGTATAGCT ACTTTGCGTT GGGCAATGAA 
CTGAACAGCT ACCGCCTCTT CCTGGGGAAC TACAGTGGCA ACGTGGGGAA GGACGCCCTC 
CTCTACCATA ACAACACCGT CTTCAGCACC AAGGACAAGG ACAACGACAA CTGCTTGGAC 
AAGTGCGCAC AGCTCCGAAA AGGTGGCTAC TGGTACAACT GCTGCACAGA CTCCAACCTC 
AATGGGGTGT ACTACCGCCT TGGCGAGCAC CGAAAGCACA TGGATGGCAT CAGCTGGTAT 
GGCTGGCATG GAGCCAACTA TTCCCTCAAA CGTGTGGAAA TGAAGATCCG CCCAGAAGCC 
TTCAAGCCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Angptl7 ( NM_001039554.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001034643.1 Mus musculus angiopoietin-like 7 (Angptl7), mRNA.

Price & Availability↑

CloneID	OMu00714
Clone ID Related Accession (Same CDS sequence)	NM_001039554.3
Accession Version	NM_001039554.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Mus musculus(house mouse)
Product	angiopoietin-related protein 7 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL713995.11. On May 2, 2007 this sequence version replaced NM_001039554.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK031675.1, BC023373.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGCTGAGGG AGACCTGGCT ATGTGTTATC CTTGTAGCCT TTGTCAGCCA CCCAGTGTGG 
CTGCAGAAGC CTCATAAACG CAAGACACAG CTCAAAGCAG CGGGCTGCTG TGAGGAGATG 
AGGGAGCTCA AAGCCCAGGT GGCCAACCTC AGCAGTCTGC TGGGAGAGCT GAGCAGGAAG 
CAGGAGAGCG ACTGGGTCAG TGTGGTCATG CAGGTGATGG AGCTGGAGAG CAGCAGCAAG 
CACATGGAGT CTCGGCTCAG CACTGCCGAG AGCAAGTACT CTGAGATGAA CAACCAGATT 
GACATCATGC AGCTGCAGGC TGCGCAGACC GTCACGCAGA CCTCGGCAGA TGCCATCTAT 
GACTGTTCTT CCCTGTACCA GAAGAACTAC CGAATCTCTG GAGTGTACAA GCTTCCTCCT 
GACGAGTTCC TGGGGAGCCC TGAGCTAGAG GTGTTCTGTG ACATGGAAAC TTCAGGAGGA 
GGCTGGACCA TCATCCAGAG ACGTAAGAGT GGCCTTGTCT CCTTCTACCA AGACTGGAGA 
CAGTATAAGC AAGGGTTTGG CAGCATCCGA GGTGACTTCT GGCTGGGGAA TGAACATATC 
CACCGGCTCA CCAGGCAGCC AAGCCGGCTT CGTGTGGAGC TGGAGGACTG GGAGGGCAAT 
GCACGCTACG CAGAGTATAG CTACTTTGCG TTGGGCAATG AACTGAACAG CTACCGCCTC 
TTCCTGGGGA ACTACAGTGG CAACGTGGGG AAGGACGCCC TCCTCTACCA TAACAACACC 
GTCTTCAGCA CCAAGGACAA GGACAACGAC AACTGCTTGG ACAAGTGCGC ACAGCTCCGA 
AAAGGTGGCT ACTGGTACAA CTGCTGCACA GACTCCAACC TCAATGGGGT GTACTACCGC 
CTTGGCGAGC ACCGAAAGCA CATGGATGGC ATCAGCTGGT ATGGCTGGCA TGGAGCCAAC 
TATTCCCTCA AACGTGTGGA AATGAAGATC CGCCCAGAAG CCTTCAAGCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034643.1
CDS	174..1187
Translation	MLRETWLCVILVAFVSHPVWLQKPHKRKTQLKAAGCCEEMRELKAQVANLSSLLGELSRKQESDWVSVVMQVMELESSSKHMESRLSTAESKYSEMNNQIDIMQLQAAQTVTQTSADAIYDCSSLYQKNYRISGVYKLPPDEFLGSPELEVFCDMETSGGGWTIIQRRKSGLVSFYQDWRQYKQGFGSIRGDFWLGNEHIHRLTRQPSRLRVELEDWEGNARYAEYSYFALGNELNSYRLFLGNYSGNVGKDALLYHNNTVFSTKDKDNDNCLDKCAQLRKGGYWYNCCTDSNLNGVYYRLGEHRKHMDGISWYGWHGANYSLKRVEMKIRPEAFKP

Target ORF information:

RefSeq Version	NM_001039554.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus angiopoietin-like 7 (Angptl7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039554.3

ORF Insert Sequence:

ATGCTGAGGG AGACCTGGCT ATGTGTTATC CTTGTAGCCT TTGTCAGCCA CCCAGTGTGG 
CTGCAGAAGC CTCATAAACG CAAGACACAG CTCAAAGCAG CGGGCTGCTG TGAGGAGATG 
AGGGAGCTCA AAGCCCAGGT GGCCAACCTC AGCAGTCTGC TGGGAGAGCT GAGCAGGAAG 
CAGGAGAGCG ACTGGGTCAG TGTGGTCATG CAGGTGATGG AGCTGGAGAG CAGCAGCAAG 
CACATGGAGT CTCGGCTCAG CACTGCCGAG AGCAAGTACT CTGAGATGAA CAACCAGATT 
GACATCATGC AGCTGCAGGC TGCGCAGACC GTCACGCAGA CCTCGGCAGA TGCCATCTAT 
GACTGTTCTT CCCTGTACCA GAAGAACTAC CGAATCTCTG GAGTGTACAA GCTTCCTCCT 
GACGAGTTCC TGGGGAGCCC TGAGCTAGAG GTGTTCTGTG ACATGGAAAC TTCAGGAGGA 
GGCTGGACCA TCATCCAGAG ACGTAAGAGT GGCCTTGTCT CCTTCTACCA AGACTGGAGA 
CAGTATAAGC AAGGGTTTGG CAGCATCCGA GGTGACTTCT GGCTGGGGAA TGAACATATC 
CACCGGCTCA CCAGGCAGCC AAGCCGGCTT CGTGTGGAGC TGGAGGACTG GGAGGGCAAT 
GCACGCTACG CAGAGTATAG CTACTTTGCG TTGGGCAATG AACTGAACAG CTACCGCCTC 
TTCCTGGGGA ACTACAGTGG CAACGTGGGG AAGGACGCCC TCCTCTACCA TAACAACACC 
GTCTTCAGCA CCAAGGACAA GGACAACGAC AACTGCTTGG ACAAGTGCGC ACAGCTCCGA 
AAAGGTGGCT ACTGGTACAA CTGCTGCACA GACTCCAACC TCAATGGGGT GTACTACCGC 
CTTGGCGAGC ACCGAAAGCA CATGGATGGC ATCAGCTGGT ATGGCTGGCA TGGAGCCAAC 
TATTCCCTCA AACGTGTGGA AATGAAGATC CGCCCAGAAG CCTTCAAGCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury.
PLoS genetics12(9)e1006355(2016 Sep)
Wu Y,Wei FY,Kawarada L,Suzuki T,Araki K,Komohara Y,Fujimura A,Kaitsuka T,Takeya M,Oike Y,Suzuki T,Tomizawa K

Angiopoietin-Like Protein 7 Promotes an Inflammatory Phenotype in RAW264.7 Macrophages Through the P38 MAPK Signaling Pathway.
Inflammation39(3)974-85(2016 Jun)
Qian T,Wang K,Cui J,He Y,Yang Z

Loss of Angiopoietin-like 7 diminishes the regeneration capacity of hematopoietic stem and progenitor cells.
Journal of hematology & oncology87(2015 Feb)
Xiao Y,Wei X,Jiang Z,Wang X,Ye W,Liu X,Zhang M,Xu Y,Wu D,Lai L,Yao H,Liu Z,Cao S,Liu P,Xu B,Li Y,Yao Y,Pei D,Li P

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Neuron83(2)309-323(2014 Jul)
Thompson CL,Ng L,Menon V,Martinez S,Lee CK,Glattfelder K,Sunkin SM,Henry A,Lau C,Dang C,Garcia-Lopez R,Martinez-Ferre A,Pombero A,Rubenstein JLR,Wakeman WB,Hohmann J,Dee N,Sodt AJ,Young R,Smith K,Nguyen TN,Kidney J,Kuan L,Jeromin A,Kaykas A,Miller J,Page D,Orta G,Bernard A,Riley Z,Smith S,Wohnoutka P,Hawrylycz MJ,Puelles L,Jones AR

A mouse knockout library for secreted and transmembrane proteins.
Nature biotechnology28(7)749-55(2010 Jul)
Tang T,Li L,Tang J,Li Y,Lin WY,Martin F,Grant D,Solloway M,Parker L,Ye W,Forrest W,Ghilardi N,Oravecz T,Platt KA,Rice DS,Hansen GM,Abuin A,Eberhart DE,Godowski P,Holt KH,Peterson A,Zambrowicz BP,de Sauvage FJ

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Angptl7 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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