Svep1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Svep1
Entrez Gene ID	64817
Full Name	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
Synonyms	1110021D17Rik,4833413O10Rik,AA387071,D430029O09Rik,Polydom
General protein information	Preferred Names sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 Names sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 polydomain protein (Polydom)
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4\|4 B3

mRNA and Protein(s)

mRNA	Protein	Name
NM_022814.2	NP_073725.2	sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SVEP1	XP_532030.2
Bos taurus (cattle)	LOC781282	XP_005210573.1
Mus musculus (house mouse)	Svep1	NP_073725.2
Danio rerio (zebrafish)	LOC567357	XP_695742.6
	SVEP1	XP_002800091.1
Homo sapiens (human)	SVEP1	NP_699197.3
Rattus norvegicus (Norway rat)	Svep1	XP_006238256.1
Gallus gallus (chicken)	SVEP1	XP_424917.4
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000685	XP_311214.5
Xenopus tropicalis (tropical clawed frog)	svep1	XP_002942667.2
Pan troglodytes (chimpanzee)	SVEP1	XP_520182.3

Gene Ontology
Bibliography

Related articles in PubMed

SVEP1 plays a crucial role in epidermal differentiation.
Samuelov L, Li Q, Bochner R, Najor NA, Albrecht L, Malchin N, Goldsmith T, Grafi-Cohen M, Vodo D, Fainberg G, Meilik B, Goldberg I, Warshauer E, Rogers T, Edie S, Ishida-Yamamoto A, Burzenski L, Erez N, Murray SA, Irvine AD, Shultz L, Green KJ, Uitto J, Sprecher E, Sarig O
Experimental dermatology26(5)423-430(2017 May)

An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation.
Karpanen T, Padberg Y, van de Pavert SA, Dierkes C, Morooka N, Peterson-Maduro J, van de Hoek G, Adrian M, Mochizuki N, Sekiguchi K, Kiefer F, Schulte D, Schulte-Merker S
Circulation research120(8)1263-1275(2017 Apr)

Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling.
Morooka N, Futaki S, Sato-Nishiuchi R, Nishino M, Totani Y, Shimono C, Nakano I, Nakajima H, Mochizuki N, Sekiguchi K
Circulation research120(8)1276-1288(2017 Apr)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Spatiotemporal regulation of GLI target genes in the mammalian limb bud.
Lewandowski JP, Du F, Zhang S, Powell MB, Falkenstein KN, Ji H, Vokes SA
Developmental biology406(1)92-103(2015 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Polydom/Svep1 is an essential extracellular factors for lymphangiogenesis.
Title: An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation.

Polydom deposited around lymphatic vessels seems to ensure Foxc2 upregulation in lymphatic endothelial cells, possibly via the Ang-2 and Tie1/Tie2 receptor system, to regulate lymphangiogenesis.
Title: Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling.

polydom is a hitherto unknown ligand for integrin alpha9beta1 that functions as a physiological ligand in vivo.
Title: Polydom/SVEP1 is a ligand for integrin ?9?1.

Our results show that the putative promoter of SVEP1 is hypermethylated in DA3- compared with MBA-15 cells, thus regulating SVEP1 expression levels
Title: SVEP1 promoter regulation by methylation of CpG sites.

The following Svep1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Svep1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu14783	NM_022814.2 Latest version!	Mus musculus sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 (Svep1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	Quote Price

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Svep1 ( NM_022814.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_073725.2 Mus musculus sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 (Svep1), mRNA.

Price & Availability↑

CloneID	OMu14783
Clone ID Related Accession (Same CDS sequence)	NM_022814.2
Accession Version	NM_022814.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 10704bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Mus musculus(house mouse)
Product	sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL805969.13 and AL929406.10. On Feb 7, 2007 this sequence version replaced NM_022814.1. Sequence Note: This RefSeq record was created using sequence from the reference genome strain C57BL/6J because transcripts from the reference strain were not available for the full length of the gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF206329.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGGTCGC GCCTGGCCTT TTGTTGCTGG GCTCTGGCAC TGGTGTCAGG CTGGACCAAC 
TTCCAGCCCG TGGCCCCTTC GCTCAACTTC AGCTTCCGCC TGTTCCCCGA GGCCTCTCCG 
GGGGCTCTGG GCAGACTGGC GGTACCTCCC GCGTCCAGTG AGGAGGAGGC AGCAGGGAGC 
AAAGTGGAGC GCCTGGGCCG CGCGTTCCGG AGCCGCGTGC GGCGACTGCG GGAGCTCAGC 
GGCAGCCTGG AGCTCGTCTT CCTGGTGGAC GAGTCGTCCA GCGTGGGCCA AACCAACTTC 
CTCAACGAGC TCAAGTTCGT GCGCAAGCTG CTGTCCGACT TCCCCGTGGT GTCCACGGCC 
ACGCGTGTGG CCATCGTCAC CTTCTCATCC AAGAACAACG TGGTGGCGCG CGTGGATTAC 
ATCTCCACCA GCCGCGCGCA CCAACACAAG TGCGCGCTAC TCAGCCGCGA GATCCCGGCC 
ATCACCTACC GCGGTGGTGG CACCTATACC AAGGGCGCCT TCCAGCAAGC CGCGCAAATC 
CTTCGTCACT CTAGAGAAAA CTCCACCAAA GTCATATTTC TCATCACCGA CGGCTATTCC 
AATGGCGGAG ACCCCAGACC TATTGCAGCA TCGCTTCGGG ATTTCGGAGT GGAGATCTTC 
ACGTTCGGGA TTTGGCAGGG GAATATCCGG GAACTGAATG ACATGGCTTC CACCCCGAAG 
GAAGAACATT GTTACCTGCT CCACAGTTTT GAAGAATTTG AGGCTTTAGC TCGCAGGGCG 
TTGCATGAAG ATCTACCTTC TGGGAGTTTT ATCCAAGAGG ATATGGCCCG CTGCTCTTAT 
CTCTGTGAGG CTGGGAAAGA CTGCTGTGAC AGAATGGCCA GCTGCAAATG TGGGACACAC 
ACGGGTCAAT TTGAATGCAT CTGTGAGAAG GGCTATTACG GGAAAGGTCT GCAGCATGAG 
TGCACAGCTT GCCCATCAGG GACATATAAG CCGGAAGCTT CTCCAGGAGG AATCAGCACC 
TGCATCCCAT GTCCTGACGT AAGCCACACC TCCCCACCTG GAAGCACTTC CCCTGAAGAC 
TGCGTGTGCC GAGAGGGATA CCAGAGATCT GGCCAGACCT GTGAGGTTGT CCACTGTCCT 
GCCCTGAAGC CTCCTGAAAA TGGTTTTTTT ATACAAAACA CTTGCAAAAA CCACTTCAAT 
GCCGCCTGTG GGGTCCGATG TCGCCCGGGC TTTGACCTTG TGGGAAGCAG CATCCATTTG 
TGTCAACCCA ATGGTTTGTG GTCTGGGACA GAAAGCTTCT GCAGAGTGAG AACGTGCCCC 
CACCTCCGAC AGCCCAAACA CGGCCACATC AGCTGCTCCA CTGCGGAAAT GTCCTACAAC 
ACCCTGTGTT TGGTTACCTG CAATGAAGGA TACAGATTAG AAGGCAGCAC TAGGCTTACC 
TGTCAAGGAA ATGCCCAGTG GGATGGCCCA GAGCCCCGGT GTGTAGAACG CCATTGTGCC 
ACCTTCCAGA AGCCCAAAGG CGTCATCATT TCTCCACCCA GCTGCGGCAA GCAGCCTGCC 
AGGCCTGGGA TGACCTGTCA GCTAAGCTGC CGCCAGGGAT ACATTTTATC CGGGGTCAGA 
GAAGTGAGAT GTGCCACATC TGGGAAGTGG AGTGCCAAAG TTCAGACAGC TGTGTGCAAA 
GATGTGGAGG CTCCACAAAT CAGCTGTCCA AATGACATTG AGGCAAAGAC TGGGGAGCAG 
CAGGACTCTG CTAATGTCAC CTGGCAAGTC CCAACAGCTA AAGACAACTC TGGTGAAAAG 
GTGTCAGTCC ACGTCCACCC AGCCTTTACC CCACCTTACC TCTTCCCAAT TGGAGACGTG 
GCCATCACCT ACACGGCAAC CGACTCATCC GGTAACCAAG CCAGCTGCAC TTTCTACATT 
AAGGTCATTG ATGTGGAACC GCCTGTCATA GATTGGTGCC GATCTCCACC TCCAATCCAG 
GTCGTAGAGA AGGAGCACCC TGCAAGCTGG GATGAGCCTC AGTTCTCAGA CAACTCCGGG 
GCTGAATTGG TCATTACCAG CAGTCACACA CAAGGCGACA TGTTTCCTCA TGGGGAAACG 
GTGGTGTGGT ACACAGCCAC TGACCCCTCA GGCAACAACA GGACCTGTGA CATCCACATT 
GTCATAAAAG GTTCTCCCTG TGAGGTCCCC TTCACCCCTG TAAACGGGGA CTTTATCTGT 
GCCCAGGATA GTGCTGGAGT TAACTGTAGC CTGAGCTGCA AGGAGGGCTA TGATTTCACA 
GAAGGGTCAA CTGAGAAGTA CTACTGTGCT TTTGAAGATG GTATCTGGAG ACCACCATAC 
TCTACAGAAT GGCCAGACTG TGCTATAAAA CGTTTTGCAA ACCATGGTTT CAAGTCCTTT 
GAAATGCTAT ACAAAACCAC TCGCTGTGAT GACATGGATC TGTTTAAGAA GTTTTCTGCA 
GCATTTGAGA CTACCCTGGG GAACATGGTC CCGTCCTTTT GTAACGATGC TGATGACATT 
GACTGCAGAC TGGAGGACCT GACCAAAAAA TACTGCATCG AGTATAATTA CAACTATGAA 
AATGGCTTTG CAATTGGACC AGGAGGCTGG GGTGCAGGCA ACAGGCTGGA TTATTCCTAC 
GATCACTTCC TGGATGTTGT ACAGGAAACA CCCACCGATG TGGGCAAGGC CAGATCGTCA 
CGGATTAAAA GAACTGTCCC ATTGTCTGAC CCCAAAATTC AGCTAATTTT TAACATCACA 
GCTAGCGTGC CACTCCCAGA GGAAAGAAAC GATACCCTTG AATTGGAGAA TCAGCAGCGA 
CTCATTAAGA CATTGGAAAC AATCACCAAT CGCCTGAAAA GCACCTTGAA TAAAGAGCCC 
ATGTATTCTT TCCAGCTCGC CTCGGAAACA GTGGTGGCTG ACAGCAATTC CCTCGAAACA 
GAAAAGGCTT TTCTCTTCTG CAGACCAGGC TCTGTGCTGA GGGGGCGCAT GTGTGTCAAC 
TGCCCCCTGG GAACCTCTTA CTCTCTGGAG CATTCCACCT GTGAAAGCTG CCTCATGGGA 
TCCTACCAAG ATGAAGAAGG GCAGCTGGAA TGCAAGCTCT GTCCCCCAAG GACTCACACG 
GAATACCTCC ATTCAAGAAG CGTCTCTGAA TGCAAAGCTC AGTGTAAGCA AGGCACCTAC 
TCTTCCAGTG GGCTGGAGAC CTGCGAATCG TGTCCGCTGG GTACTTATCA ACCGGAATTT 
GGATCCCGGA GCTGCCTCCT ATGCCCAGAA ACCACCACAA CGGTGAAAAG AGGAGCCGTG 
GACATCTCTG CTTGTGGAGT GCCCTGCCCA GTAGGAGAAT TCTCCCGTTC TGGGCTAACA 
CCCTGCTACC CTTGCCCTCG AGACTATTAC CAACCCAATG CAGGGAAGTC CTTCTGCCTC 
GCTTGTCCCT TTTATGGAAC TACAACCATC ACTGGCGCCA CGTCCATCAC AGACTGCTCA 
AGTTTTAGCT CTACTTTCTC AGCAGCAGAA GAAAGCATAG TGCCCCTCGT GGCCCCTGGA 
CATTCCCAGA ACAAGTACGA AGTCAGCAGT CAGGTCTTTC ACGAATGCTT CTTAAACCCC 
TGCCACAACA GTGGAACCTG CCAACAGCTT GGGCGTGGTT ATGTCTGTCT CTGCCCACCT 
GGATACACAG GCTTAAAGTG TGAAACAGAT ATTGATGAAT GCAGCTCTCT GCCTTGCCTC 
AATGGTGGAA TTTGTAGAGA CCAAGTTGGG GGATTCACGT GCGAATGTTC ATTGGGCTAT 
TCAGGTCAAA TATGTGAAGA AAATATAAAT GAGTGTATCT CCAGCCCTTG CTTAAATAAA 
GGAACCTGCA CTGACGGCTT GGCAAGCTAC CGCTGTACCT GTGTGAAAGG ATACATGGGT 
GTGCACTGTG AAACAGACGT CAATGAATGC CAGTCAAGCC CCTGCTTAAA CAACGCAGTT 
TGTAAAGACC AAGTTGGGGG GTTCTCATGC AAATGCCCAC CCGGATTTTT GGGTACTCGG 
TGTGAAAAAA ATGTGGATGA GTGTCTCAGT CAGCCATGCC AAAATGGAGC CACTTGTAAG 
GATGGTGCCA ACAGCTTCAG GTGTCAATGT CCAGCAGGCT TCACAGGGAC ACACTGTGAA 
CTGAACATCA ACGAGTGTCA GTCCAACCCA TGTAGGAACC AGGCCACCTG TGTGGATGAA 
CTAAACTCAT ACAGTTGTAA ATGTCAGCCA GGATTTTCAG GCCACAGGTG TGAGACAGAA 
CAGCCTTCCG GTTTTAACCT GGATTTTGAA GTTTCTGGCA TCTACGGGTA CGTCCTGCTA 
GATGGAGTGC TGCCAACCCT CCATGCCATA ACCTGCGCAT TCTGGATGAA ATCCTCTGAT 
GTCATCAACT ACGGGACGCC CATCTCCTAT GCACTTGAGG ATGACAAAGA CAACACCTTC 
CTCCTGACTG ATTACAACGG CTGGGTTCTT TATGTGAATG GAAAGGAAAA GATCACCAAC 
TGCCCCTCCG TAAATGATGG CATTTGGCAT CATATTGCAA TCACATGGAC AAGTACTGGT 
GGAGCCTGGA GGGTCTATAT AGATGGGGAA TTATCTGACG GTGGTACTGG CCTCTCCATT 
GGCAAAGCCA TACCTGGTGG CGGTGCATTA GTTCTTGGGC AAGAGCAAGA CAAAAAAGGA 
GAGGGGTTCA ACCCGGCTGA GTCTTTTGTG GGCTCCATAA GCCAGCTCAA CCTCTGGGAC 
TATGTCCTGT CTCCACAGCA GGTGAAGTTG CTGGCCAGCT CCTGCCCAGA GGAACTGAGT 
CGGGGAAACG TGTTAGCATG GCCCGATTTC CTGTCGGGAA TCACGGGGAA GGTGAAGGTT 
GATTCCAGCA GCATGTTCTG CTCTGATTGT CCGTCTTTAG AAGGATCCGT GCCTCACCTG 
AGACCTGCAT CAGGAAATCG AAAGCCAGGC TCCAAAGTCA GTCTGTTCTG TGATCCGGGC 
TTCCAGATGG TTGGGAATCC TGTGCAGTAT TGTCTGAACC AAGGGCAGTG GACACAACCA 
CTCCCCCACT GTGAACGCAT TCGCTGTGGG CTGCCTCCCG CCTTGGAGAA TGGCTTCTAC 
TCAGCCGAGG ACTTCCATGC GGGCAGCACG GTGACCTATC AGTGCACCAG TGGCTACTAC 
CTGCTGGGTG ATTCCCGAAT GTTCTGCACA GACAACGGGA GCTGGAACGG CATTTCACCA 
TCCTGTCTCG ATGTCGATGA GTGTGCAGTC GGCTCGGACT GTAGTGAGCA CGCCTCCTGC 
CTGAACACCA ACGGATCCTA CGTATGTTCC TGTAACCCAC CATACACGGG AGATGGGAAA 
AACTGTGCAG AACCTGTAAA ATGTAAGGCT CCAGAAAATC CAGAAAATGG CCACTCTTCT 
GGTGAGATTT ACACCGTGGG TACTGCAGTC ACATTTTCCT GTGACGAAGG GCACGAGCTG 
GTGGGAGTGA GCACCATCAC GTGTTTGGAG ACTGGCGAGT GGGATCGCCT CAGGCCGTCC 
TGTGAAGCCA TTTCCTGTGG TGTCCCACCT GTTCCTGAAA ATGGTGGTGT TGACGGGTCG 
GCATTCACAT ACGGCAGTAA GGTGGTGTAC AGGTGTGATA AAGGATATAC TTTGTCTGGG 
GATGAAGAGT CAGCATGCCT TGCTAGTGGT TCCTGGAGTC ATTCCTCTCC TGTGTGCGAG 
CTAGTGAAGT GTTCCCAGCC TGAGGACATA AATAACGGCA AATACATCTT AAGTGGGCTC 
ACCTACCTTT CTATTGCATC GTACTCCTGT GAGAACGGAT ACAGTTTACA GGGCCCATCC 
CTCCTTGAAT GCACAGCTTC CGGCAGCTGG GACAGAGCGC CACCTAGCTG TCAACTTGTC 
TCCTGCGGAG AGCCTCCAAT CGTCAAAGAT GCTGTCATCA CTGGGAGCAA CTTCACTTTT 
GGGAACACAG TTGCTTACAC ATGCAAAGAG GGCTACACCC TTGCTGGGCC TGACACCATC 
GTATGCCAGG CCAACGGCAA ATGGAATTCA AGTAACCACC AGTGCCTGGC TGTCTCCTGT 
GACGAGCCCC CCAATGTGGA CCACGCCTCT CCAGAGACTG CTCACAGGCT CTTTGGAGAC 
ACCGCGTTTT ACTACTGTGC GGATGGTTAC AGCCTGGCTG ATAATTCCCA GCTCATCTGC 
AATGCCCAGG GGAACTGGGT TCCCCCCGCG GGCCAGGCTG TGCCGCGCTG CATAGCTCAC 
TTCTGTGAAA AACCCCCATC TGTTTCCTAC AGCATCTTGG AATCTGTGAG CAAAGCAAAG 
TTTGCAGCTG GCTCGGTAGT GAGCTTCAAG TGCATGGAGG GTTTTGTGCT GAACACCTCA 
GCGAAGATTG AATGCCTGAG AGGTGGAGAG TGGAGCCCTT CTCCCCTCTC GGTCCAGTGC 
ATCCCGGTGC GATGCGGAGA GCCTCCAAGC ATCGCAAATG GCTACCCGAG TGGGACAAAC 
TACAGTTTTG GGGCCGTGGT GGCCTACAGC TGCCACAAGG GATTCTATAT CAAGGGGGAG 
AAGAAGAGCA CGTGTGAGGC CACAGGACAG TGGAGTAAAC CCACGCCCAC CTGCCATCCT 
GTGTCCTGTA ACGAGCCACC TAAGGTTGAG AACGGCTTCC TGGAGCACAC CACTGGCAGG 
ACCTTTGAGA GCGAAGCAAG GTTCCAGTGC AACCCAGGCT ATAAGGCAGC CGGAAGTCCT 
GTGTTTGTTT GCCAAGCCAA TCGCCACTGG CACAGCGACG CCCCTCTGTC CTGCACCCCT 
CTCAACTGTG GGAAACCCCC TCCCATTCAG AATGGCTTTT TGAAAGGAGA AAGCTTTGAA 
GTAGGGTCCA AGGTTCAGTT TGTCTGTAAT GAGGGATATG AGCTCGTTGG TGATAATTCT 
TGGACTTGCC AGAAATCTGG CAAATGGAGT AAGAAGCCAA GCCCGAAGTG TGTCCCCACC 
AAGTGTGCAG AGCCTCCTCT CTTAGAAAAC CAGCTCGTAT TGAAGGAATT AGCTTCCGAG 
GTAGGAGTGA TGACCATTTC CTGTAAAGAG GGGCATGCCT TGCAAGGCCC CTCTGTCCTG 
AAGTGCTTGC CATCCGGGCA ATGGAATGGT TCCTTTCCTA TTTGTAAGAT GGTCCTTTGT 
CCCTCGCCTC CCTTGATTCC CTTCGGCGTC CCTGCGTCTT CCGGTGCTCT TCATTTTGGC 
AGTACTGTCA AGTATCTGTG TGTCGACGGG TTTTTCTTAA GAGGCAGTCC AACCATCCTC 
TGCCAGGCTG ATAGCACCTG GAGTTCTCCA TTGCCCGAAT GCGTTCCGGT AGAATGTCCC 
CAACCTGAGG AGATCCTCAA CGGTATCATC CACGTACAAG GGCTTGCCTA TCTCAGCACC 
ACGCTCTACA CCTGCAAGCC AGGCTTTGAG TTAGTGGGCA ATGCTACCAC CCTCTGTGGG 
GAAAATGGCC AGTGGCTCGG AGGAAAACCA ATGTGCAAAC CCATTGAATG CCCAGAGCCC 
AAGGAGATTT TAAATGGCCA ATTCTCTTCC GTGAGCTTTC AGTATGGACA AACCATCACA 
TACTTTTGTG ACCGGGGCTT CCGGCTCGAA GGTCCCAAAT CCCTGACCTG TTTAGAGACA 
GGTGACTGGG ATATGGATCC CCCCTCTTGT GATGCCATCC ACTGCAGTGA CCCACAGCCC 
ATTGAAAATG GTTTCGTAGA AGGTGCGGAT TACAGATACG GTGCCATGAT CATCTATAGC 
TGCTTCCCTG GGTTTCAGGT GCTTGGTCAT GCCATGCAGA CCTGTGAAGA GTCGGGATGG 
TCAAGCTCCA GCCCAACCTG TGTACCCATA GACTGCGGTC TCCCTCCTCA CATAGACTTT 
GGTGACTGTA CTAAAGTCAG AGATGGCCAG GGACATTTTG ATCAAGAAGA TGACATGATG 
GAAGTCCCAT ATCTGGCTCA CCCTCAACAT TTGGAAGCAA CAGCTAAGGC CTTGGAAAAT 
ACAAAGGAGT CGCCTGCCTC ACATGCATCC CACTTCCTCT ATGGCACGAT GGTTTCCTAC 
AGCTGCGAGC CTGGTTATGA ACTGCTGGGA ATCCCTGTGC TGATCTGCCA GGAAGATGGT 
ACGTGGAATG GTACCGCACC CTCTTGCATT TCCATTGAAT GTGATTTGCC TGTTGCTCCC 
GAAAATGGCT TTTTACATTT CACACAGACG ACTATGGGCA GTGCTGCACA ATATAGCTGC 
AAGCCGGGGC ACATTCTAGA AGGCTCCCAC TTAAGACTCT GTCTGCAGAA TAAGCAGTGG 
AGTGGCACTG TTCCACGCTG TGAAGCCATC TCATGCAGTA AGCCAAACCC ACTCTGGAAT 
GGATCCATCA AAGGAGATGA CTACTCCTAC CTGGGTGTGT TATACTACGA GTGTGACTCT 
GGCTATATTC TCAATGGCTC TAAGAAGAGG ACATGCCAAG AAAATAGAGA TTGGGATGGG 
CATGAGCCCA TGTGTATTCC TGTAGACTGT GGCTCACCCC CAGTCCCCAC CAATGGCCGA 
GTGAAGGGAG AAGAATACAC ATTCCAAAAG GAGATTACAT ACTCTTGCCG TGAAGGGTTC 
ATACTGGAAG GAGCCAGGAG TCGTATCTGT CTTACCAATG GAAGTTGGAG TGGTGCCACT 
CCCAGCTGCA TGCCTGTTAG ATGTCCTGCC CCACCACAGG TGCCAAATGG GGTGGCAGAT 
GGCCTAGACT ATGGGTTCAA GAAGGAAGTA GCGTTCCACT GTCTAGAGGG CTATGTGCTG 
CAGGGGGCTC CAAGACTCAC CTGTCAGTCC AATGGGACTT GGGATGCAGA AGTCCCTGTC 
TGTAAACCAG CTACCTGTGG TCCTCCTGCC GACCTTCCCC AGGGCTTCCC TAATGGCTTT 
TCTTTTTATC ATGGGGGCCA CATACAGTAT CAGTGTTTTA CTGGTTATAA GCTTCATGGA 
AACCCATCAA GAAGATGCCT TCCCAATGGT TCCTGGAGCG GCAGCTCGCC ATCCTGCCTA 
CCTTGCAGGT GTTCCACACC CATCATTCAA CAGGGAACCA TCAACGCAAC TGATTTGGGA 
TGTGGAAAGA CGGTCCAGAT TGAGTGCTTC AAAGGCTTCA AGCTGCTTGG ACTTTCTGAA 
ATCACCTGTG ATGCCAATGG CCAATGGTCT GACGTCCCAC TGTGTGAGCA CGCTCAGTGC 
GGGCCTCTCC CAACCATACC CAACGCAATT GTCCTTGAGG GCAGCCTTTC GGAGGACAAT 
GTGGTAACTT ACAGCTGCAG ACCTGGCTAC ACCATGCAAG GTAGTTCAGA TCTGATTTGT 
ACGGAAAAAG CGATATGGAG CCAGCCTTAC CCAACGTGTG AACCCCTGTC CTGTGGACCC 
CCACCAACTG TAGCCAATGC AGTGGCAACA GGAGAGGCTC ATACCTATGA AAGCAAAGTG 
AAACTCAGGT GTCTGGAAGG GTATGTGATG GATTCGGATA CAGATACATT CACCTGCCAG 
CAAGATGGCC ATTGGGTCCC TGAAAGAATC ACCTGCAGTC CTAAAAAATG CCCTGTGCCA 
TCCAACATGA CACGCATACG TTTTCACGGA GATGACTTCC AGGTGAACAG ACAAGTTTCT 
GTGTCATGTG CAGAAGGGTT TACCCACGAA GGAGTGAACT GGTCAACATG CCAGCCCGAC 
GGTACATGGG AGCCACCATT TTCTGATGAA TCCTGTATCC CAGTTGTTTG TGGGCATCCT 
GAAAGCCCAG CGCATGGCTC CGTGGTTGGC AATAAGCACA GCTTTGGAAG CACCATTGTT 
TACCAGTGTG ACCCTGGCTA CAAATTAGAG GGGAACAGGG AACGAATCTG CCAGGAGAAC 
AGACAGTGGA GTGGAGAGGT GGCAGTGTGC AGAGAGAACA GATGTGAGAC TCCAGCTGAG 
TTTCCCAATG GGAAGGCTGT CTTGGAAAAC ACCACATCTG GACCCAGCCT TCTGTTTTCC 
TGTCACAGAG GCTACACCCT GGAAGGGTCC CCCGAGGCAC ACTGCACTGC AAATGGAACC 
TGGAATCACC TGACTCCCCT CTGCAAACCA AATCCATGCC CTGTCCCTTT TGTGATTCCT 
GAGAACGCCG TCCTTTCTGA AAAAGAGTTT TATGTCGACC AGAATGTATC TATCAAGTGC 
AGGGAAGGCT TCCTGCTCAA AGGCAATGGT GTCATCACGT GCAGCCCTGA CGAGACATGG 
ACGCACACCA ATGCCAGATG TGAAAAAATC TCCTGTGGTC CTCCAAGTCA CGTAGAGAAT 
GCAATTGCTC GAGGAGTGTA TTACCAGTAT GGGGACATGA TCACCTACTC CTGTTACAGT 
GGCTACATGC TAGAAGGTTC CCTCCGGAGT GTTTGCCTAG AAAATGGAAC ATGGACACCA 
TCTCCTGTTT GCAGAGCTGT CTGTCGGTTC CCATGTCAGA ATGGAGGTGT CTGTCAACGT 
CCAAATGCTT GCTCATGCCC AGACGGCTGG ATGGGACGTC TCTGTGAAGA GCCAATATGC 
ATACTCCCCT GTTTGAATGG TGGGCGCTGT GTGGCCCCTT ATCAGTGTGA CTGCCCCACA 
GGCTGGACTG GGTCCCGCTG TCATACAGCT ACTTGTCAGT CCCCCTGCTT AAATGGCGGG 
AAATGCATAA GACCAAACCG ATGCCATTGT CTCTCAGCCT GGACAGGACA TGATTGTTCC 
AGGAAAAGGA GAGCCGGGCT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_073725.2
CDS	221..10924
Translation	MWSRLAFCCWALALVSGWTNFQPVAPSLNFSFRLFPEASPGALGRLAVPPASSEEEAAGSKVERLGRAFRSRVRRLRELSGSLELVFLVDESSSVGQTNFLNELKFVRKLLSDFPVVSTATRVAIVTFSSKNNVVARVDYISTSRAHQHKCALLSREIPAITYRGGGTYTKGAFQQAAQILRHSRENSTKVIFLITDGYSNGGDPRPIAASLRDFGVEIFTFGIWQGNIRELNDMASTPKEEHCYLLHSFEEFEALARRALHEDLPSGSFIQEDMARCSYLCEAGKDCCDRMASCKCGTHTGQFECICEKGYYGKGLQHECTACPSGTYKPEASPGGISTCIPCPDVSHTSPPGSTSPEDCVCREGYQRSGQTCEVVHCPALKPPENGFFIQNTCKNHFNAACGVRCRPGFDLVGSSIHLCQPNGLWSGTESFCRVRTCPHLRQPKHGHISCSTAEMSYNTLCLVTCNEGYRLEGSTRLTCQGNAQWDGPEPRCVERHCATFQKPKGVIISPPSCGKQPARPGMTCQLSCRQGYILSGVREVRCATSGKWSAKVQTAVCKDVEAPQISCPNDIEAKTGEQQDSANVTWQVPTAKDNSGEKVSVHVHPAFTPPYLFPIGDVAITYTATDSSGNQASCTFYIKVIDVEPPVIDWCRSPPPIQVVEKEHPASWDEPQFSDNSGAELVITSSHTQGDMFPHGETVVWYTATDPSGNNRTCDIHIVIKGSPCEVPFTPVNGDFICAQDSAGVNCSLSCKEGYDFTEGSTEKYYCAFEDGIWRPPYSTEWPDCAIKRFANHGFKSFEMLYKTTRCDDMDLFKKFSAAFETTLGNMVPSFCNDADDIDCRLEDLTKKYCIEYNYNYENGFAIGPGGWGAGNRLDYSYDHFLDVVQETPTDVGKARSSRIKRTVPLSDPKIQLIFNITASVPLPEERNDTLELENQQRLIKTLETITNRLKSTLNKEPMYSFQLASETVVADSNSLETEKAFLFCRPGSVLRGRMCVNCPLGTSYSLEHSTCESCLMGSYQDEEGQLECKLCPPRTHTEYLHSRSVSECKAQCKQGTYSSSGLETCESCPLGTYQPEFGSRSCLLCPETTTTVKRGAVDISACGVPCPVGEFSRSGLTPCYPCPRDYYQPNAGKSFCLACPFYGTTTITGATSITDCSSFSSTFSAAEESIVPLVAPGHSQNKYEVSSQVFHECFLNPCHNSGTCQQLGRGYVCLCPPGYTGLKCETDIDECSSLPCLNGGICRDQVGGFTCECSLGYSGQICEENINECISSPCLNKGTCTDGLASYRCTCVKGYMGVHCETDVNECQSSPCLNNAVCKDQVGGFSCKCPPGFLGTRCEKNVDECLSQPCQNGATCKDGANSFRCQCPAGFTGTHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGHRCETEQPSGFNLDFEVSGIYGYVLLDGVLPTLHAITCAFWMKSSDVINYGTPISYALEDDKDNTFLLTDYNGWVLYVNGKEKITNCPSVNDGIWHHIAITWTSTGGAWRVYIDGELSDGGTGLSIGKAIPGGGALVLGQEQDKKGEGFNPAESFVGSISQLNLWDYVLSPQQVKLLASSCPEELSRGNVLAWPDFLSGITGKVKVDSSSMFCSDCPSLEGSVPHLRPASGNRKPGSKVSLFCDPGFQMVGNPVQYCLNQGQWTQPLPHCERIRCGLPPALENGFYSAEDFHAGSTVTYQCTSGYYLLGDSRMFCTDNGSWNGISPSCLDVDECAVGSDCSEHASCLNTNGSYVCSCNPPYTGDGKNCAEPVKCKAPENPENGHSSGEIYTVGTAVTFSCDEGHELVGVSTITCLETGEWDRLRPSCEAISCGVPPVPENGGVDGSAFTYGSKVVYRCDKGYTLSGDEESACLASGSWSHSSPVCELVKCSQPEDINNGKYILSGLTYLSIASYSCENGYSLQGPSLLECTASGSWDRAPPSCQLVSCGEPPIVKDAVITGSNFTFGNTVAYTCKEGYTLAGPDTIVCQANGKWNSSNHQCLAVSCDEPPNVDHASPETAHRLFGDTAFYYCADGYSLADNSQLICNAQGNWVPPAGQAVPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECLRGGEWSPSPLSVQCIPVRCGEPPSIANGYPSGTNYSFGAVVAYSCHKGFYIKGEKKSTCEATGQWSKPTPTCHPVSCNEPPKVENGFLEHTTGRTFESEARFQCNPGYKAAGSPVFVCQANRHWHSDAPLSCTPLNCGKPPPIQNGFLKGESFEVGSKVQFVCNEGYELVGDNSWTCQKSGKWSKKPSPKCVPTKCAEPPLLENQLVLKELASEVGVMTISCKEGHALQGPSVLKCLPSGQWNGSFPICKMVLCPSPPLIPFGVPASSGALHFGSTVKYLCVDGFFLRGSPTILCQADSTWSSPLPECVPVECPQPEEILNGIIHVQGLAYLSTTLYTCKPGFELVGNATTLCGENGQWLGGKPMCKPIECPEPKEILNGQFSSVSFQYGQTITYFCDRGFRLEGPKSLTCLETGDWDMDPPSCDAIHCSDPQPIENGFVEGADYRYGAMIIYSCFPGFQVLGHAMQTCEESGWSSSSPTCVPIDCGLPPHIDFGDCTKVRDGQGHFDQEDDMMEVPYLAHPQHLEATAKALENTKESPASHASHFLYGTMVSYSCEPGYELLGIPVLICQEDGTWNGTAPSCISIECDLPVAPENGFLHFTQTTMGSAAQYSCKPGHILEGSHLRLCLQNKQWSGTVPRCEAISCSKPNPLWNGSIKGDDYSYLGVLYYECDSGYILNGSKKRTCQENRDWDGHEPMCIPVDCGSPPVPTNGRVKGEEYTFQKEITYSCREGFILEGARSRICLTNGSWSGATPSCMPVRCPAPPQVPNGVADGLDYGFKKEVAFHCLEGYVLQGAPRLTCQSNGTWDAEVPVCKPATCGPPADLPQGFPNGFSFYHGGHIQYQCFTGYKLHGNPSRRCLPNGSWSGSSPSCLPCRCSTPIIQQGTINATDLGCGKTVQIECFKGFKLLGLSEITCDANGQWSDVPLCEHAQCGPLPTIPNAIVLEGSLSEDNVVTYSCRPGYTMQGSSDLICTEKAIWSQPYPTCEPLSCGPPPTVANAVATGEAHTYESKVKLRCLEGYVMDSDTDTFTCQQDGHWVPERITCSPKKCPVPSNMTRIRFHGDDFQVNRQVSVSCAEGFTHEGVNWSTCQPDGTWEPPFSDESCIPVVCGHPESPAHGSVVGNKHSFGSTIVYQCDPGYKLEGNRERICQENRQWSGEVAVCRENRCETPAEFPNGKAVLENTTSGPSLLFSCHRGYTLEGSPEAHCTANGTWNHLTPLCKPNPCPVPFVIPENAVLSEKEFYVDQNVSIKCREGFLLKGNGVITCSPDETWTHTNARCEKISCGPPSHVENAIARGVYYQYGDMITYSCYSGYMLEGSLRSVCLENGTWTPSPVCRAVCRFPCQNGGVCQRPNACSCPDGWMGRLCEEPICILPCLNGGRCVAPYQCDCPTGWTGSRCHTATCQSPCLNGGKCIRPNRCHCLSAWTGHDCSRKRRAGL

Target ORF information:

RefSeq Version	NM_022814.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 (Svep1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022814.2

ORF Insert Sequence:

ATGTGGTCGC GCCTGGCCTT TTGTTGCTGG GCTCTGGCAC TGGTGTCAGG CTGGACCAAC 
TTCCAGCCCG TGGCCCCTTC GCTCAACTTC AGCTTCCGCC TGTTCCCCGA GGCCTCTCCG 
GGGGCTCTGG GCAGACTGGC GGTACCTCCC GCGTCCAGTG AGGAGGAGGC AGCAGGGAGC 
AAAGTGGAGC GCCTGGGCCG CGCGTTCCGG AGCCGCGTGC GGCGACTGCG GGAGCTCAGC 
GGCAGCCTGG AGCTCGTCTT CCTGGTGGAC GAGTCGTCCA GCGTGGGCCA AACCAACTTC 
CTCAACGAGC TCAAGTTCGT GCGCAAGCTG CTGTCCGACT TCCCCGTGGT GTCCACGGCC 
ACGCGTGTGG CCATCGTCAC CTTCTCATCC AAGAACAACG TGGTGGCGCG CGTGGATTAC 
ATCTCCACCA GCCGCGCGCA CCAACACAAG TGCGCGCTAC TCAGCCGCGA GATCCCGGCC 
ATCACCTACC GCGGTGGTGG CACCTATACC AAGGGCGCCT TCCAGCAAGC CGCGCAAATC 
CTTCGTCACT CTAGAGAAAA CTCCACCAAA GTCATATTTC TCATCACCGA CGGCTATTCC 
AATGGCGGAG ACCCCAGACC TATTGCAGCA TCGCTTCGGG ATTTCGGAGT GGAGATCTTC 
ACGTTCGGGA TTTGGCAGGG GAATATCCGG GAACTGAATG ACATGGCTTC CACCCCGAAG 
GAAGAACATT GTTACCTGCT CCACAGTTTT GAAGAATTTG AGGCTTTAGC TCGCAGGGCG 
TTGCATGAAG ATCTACCTTC TGGGAGTTTT ATCCAAGAGG ATATGGCCCG CTGCTCTTAT 
CTCTGTGAGG CTGGGAAAGA CTGCTGTGAC AGAATGGCCA GCTGCAAATG TGGGACACAC 
ACGGGTCAAT TTGAATGCAT CTGTGAGAAG GGCTATTACG GGAAAGGTCT GCAGCATGAG 
TGCACAGCTT GCCCATCAGG GACATATAAG CCGGAAGCTT CTCCAGGAGG AATCAGCACC 
TGCATCCCAT GTCCTGACGT AAGCCACACC TCCCCACCTG GAAGCACTTC CCCTGAAGAC 
TGCGTGTGCC GAGAGGGATA CCAGAGATCT GGCCAGACCT GTGAGGTTGT CCACTGTCCT 
GCCCTGAAGC CTCCTGAAAA TGGTTTTTTT ATACAAAACA CTTGCAAAAA CCACTTCAAT 
GCCGCCTGTG GGGTCCGATG TCGCCCGGGC TTTGACCTTG TGGGAAGCAG CATCCATTTG 
TGTCAACCCA ATGGTTTGTG GTCTGGGACA GAAAGCTTCT GCAGAGTGAG AACGTGCCCC 
CACCTCCGAC AGCCCAAACA CGGCCACATC AGCTGCTCCA CTGCGGAAAT GTCCTACAAC 
ACCCTGTGTT TGGTTACCTG CAATGAAGGA TACAGATTAG AAGGCAGCAC TAGGCTTACC 
TGTCAAGGAA ATGCCCAGTG GGATGGCCCA GAGCCCCGGT GTGTAGAACG CCATTGTGCC 
ACCTTCCAGA AGCCCAAAGG CGTCATCATT TCTCCACCCA GCTGCGGCAA GCAGCCTGCC 
AGGCCTGGGA TGACCTGTCA GCTAAGCTGC CGCCAGGGAT ACATTTTATC CGGGGTCAGA 
GAAGTGAGAT GTGCCACATC TGGGAAGTGG AGTGCCAAAG TTCAGACAGC TGTGTGCAAA 
GATGTGGAGG CTCCACAAAT CAGCTGTCCA AATGACATTG AGGCAAAGAC TGGGGAGCAG 
CAGGACTCTG CTAATGTCAC CTGGCAAGTC CCAACAGCTA AAGACAACTC TGGTGAAAAG 
GTGTCAGTCC ACGTCCACCC AGCCTTTACC CCACCTTACC TCTTCCCAAT TGGAGACGTG 
GCCATCACCT ACACGGCAAC CGACTCATCC GGTAACCAAG CCAGCTGCAC TTTCTACATT 
AAGGTCATTG ATGTGGAACC GCCTGTCATA GATTGGTGCC GATCTCCACC TCCAATCCAG 
GTCGTAGAGA AGGAGCACCC TGCAAGCTGG GATGAGCCTC AGTTCTCAGA CAACTCCGGG 
GCTGAATTGG TCATTACCAG CAGTCACACA CAAGGCGACA TGTTTCCTCA TGGGGAAACG 
GTGGTGTGGT ACACAGCCAC TGACCCCTCA GGCAACAACA GGACCTGTGA CATCCACATT 
GTCATAAAAG GTTCTCCCTG TGAGGTCCCC TTCACCCCTG TAAACGGGGA CTTTATCTGT 
GCCCAGGATA GTGCTGGAGT TAACTGTAGC CTGAGCTGCA AGGAGGGCTA TGATTTCACA 
GAAGGGTCAA CTGAGAAGTA CTACTGTGCT TTTGAAGATG GTATCTGGAG ACCACCATAC 
TCTACAGAAT GGCCAGACTG TGCTATAAAA CGTTTTGCAA ACCATGGTTT CAAGTCCTTT 
GAAATGCTAT ACAAAACCAC TCGCTGTGAT GACATGGATC TGTTTAAGAA GTTTTCTGCA 
GCATTTGAGA CTACCCTGGG GAACATGGTC CCGTCCTTTT GTAACGATGC TGATGACATT 
GACTGCAGAC TGGAGGACCT GACCAAAAAA TACTGCATCG AGTATAATTA CAACTATGAA 
AATGGCTTTG CAATTGGACC AGGAGGCTGG GGTGCAGGCA ACAGGCTGGA TTATTCCTAC 
GATCACTTCC TGGATGTTGT ACAGGAAACA CCCACCGATG TGGGCAAGGC CAGATCGTCA 
CGGATTAAAA GAACTGTCCC ATTGTCTGAC CCCAAAATTC AGCTAATTTT TAACATCACA 
GCTAGCGTGC CACTCCCAGA GGAAAGAAAC GATACCCTTG AATTGGAGAA TCAGCAGCGA 
CTCATTAAGA CATTGGAAAC AATCACCAAT CGCCTGAAAA GCACCTTGAA TAAAGAGCCC 
ATGTATTCTT TCCAGCTCGC CTCGGAAACA GTGGTGGCTG ACAGCAATTC CCTCGAAACA 
GAAAAGGCTT TTCTCTTCTG CAGACCAGGC TCTGTGCTGA GGGGGCGCAT GTGTGTCAAC 
TGCCCCCTGG GAACCTCTTA CTCTCTGGAG CATTCCACCT GTGAAAGCTG CCTCATGGGA 
TCCTACCAAG ATGAAGAAGG GCAGCTGGAA TGCAAGCTCT GTCCCCCAAG GACTCACACG 
GAATACCTCC ATTCAAGAAG CGTCTCTGAA TGCAAAGCTC AGTGTAAGCA AGGCACCTAC 
TCTTCCAGTG GGCTGGAGAC CTGCGAATCG TGTCCGCTGG GTACTTATCA ACCGGAATTT 
GGATCCCGGA GCTGCCTCCT ATGCCCAGAA ACCACCACAA CGGTGAAAAG AGGAGCCGTG 
GACATCTCTG CTTGTGGAGT GCCCTGCCCA GTAGGAGAAT TCTCCCGTTC TGGGCTAACA 
CCCTGCTACC CTTGCCCTCG AGACTATTAC CAACCCAATG CAGGGAAGTC CTTCTGCCTC 
GCTTGTCCCT TTTATGGAAC TACAACCATC ACTGGCGCCA CGTCCATCAC AGACTGCTCA 
AGTTTTAGCT CTACTTTCTC AGCAGCAGAA GAAAGCATAG TGCCCCTCGT GGCCCCTGGA 
CATTCCCAGA ACAAGTACGA AGTCAGCAGT CAGGTCTTTC ACGAATGCTT CTTAAACCCC 
TGCCACAACA GTGGAACCTG CCAACAGCTT GGGCGTGGTT ATGTCTGTCT CTGCCCACCT 
GGATACACAG GCTTAAAGTG TGAAACAGAT ATTGATGAAT GCAGCTCTCT GCCTTGCCTC 
AATGGTGGAA TTTGTAGAGA CCAAGTTGGG GGATTCACGT GCGAATGTTC ATTGGGCTAT 
TCAGGTCAAA TATGTGAAGA AAATATAAAT GAGTGTATCT CCAGCCCTTG CTTAAATAAA 
GGAACCTGCA CTGACGGCTT GGCAAGCTAC CGCTGTACCT GTGTGAAAGG ATACATGGGT 
GTGCACTGTG AAACAGACGT CAATGAATGC CAGTCAAGCC CCTGCTTAAA CAACGCAGTT 
TGTAAAGACC AAGTTGGGGG GTTCTCATGC AAATGCCCAC CCGGATTTTT GGGTACTCGG 
TGTGAAAAAA ATGTGGATGA GTGTCTCAGT CAGCCATGCC AAAATGGAGC CACTTGTAAG 
GATGGTGCCA ACAGCTTCAG GTGTCAATGT CCAGCAGGCT TCACAGGGAC ACACTGTGAA 
CTGAACATCA ACGAGTGTCA GTCCAACCCA TGTAGGAACC AGGCCACCTG TGTGGATGAA 
CTAAACTCAT ACAGTTGTAA ATGTCAGCCA GGATTTTCAG GCCACAGGTG TGAGACAGAA 
CAGCCTTCCG GTTTTAACCT GGATTTTGAA GTTTCTGGCA TCTACGGGTA CGTCCTGCTA 
GATGGAGTGC TGCCAACCCT CCATGCCATA ACCTGCGCAT TCTGGATGAA ATCCTCTGAT 
GTCATCAACT ACGGGACGCC CATCTCCTAT GCACTTGAGG ATGACAAAGA CAACACCTTC 
CTCCTGACTG ATTACAACGG CTGGGTTCTT TATGTGAATG GAAAGGAAAA GATCACCAAC 
TGCCCCTCCG TAAATGATGG CATTTGGCAT CATATTGCAA TCACATGGAC AAGTACTGGT 
GGAGCCTGGA GGGTCTATAT AGATGGGGAA TTATCTGACG GTGGTACTGG CCTCTCCATT 
GGCAAAGCCA TACCTGGTGG CGGTGCATTA GTTCTTGGGC AAGAGCAAGA CAAAAAAGGA 
GAGGGGTTCA ACCCGGCTGA GTCTTTTGTG GGCTCCATAA GCCAGCTCAA CCTCTGGGAC 
TATGTCCTGT CTCCACAGCA GGTGAAGTTG CTGGCCAGCT CCTGCCCAGA GGAACTGAGT 
CGGGGAAACG TGTTAGCATG GCCCGATTTC CTGTCGGGAA TCACGGGGAA GGTGAAGGTT 
GATTCCAGCA GCATGTTCTG CTCTGATTGT CCGTCTTTAG AAGGATCCGT GCCTCACCTG 
AGACCTGCAT CAGGAAATCG AAAGCCAGGC TCCAAAGTCA GTCTGTTCTG TGATCCGGGC 
TTCCAGATGG TTGGGAATCC TGTGCAGTAT TGTCTGAACC AAGGGCAGTG GACACAACCA 
CTCCCCCACT GTGAACGCAT TCGCTGTGGG CTGCCTCCCG CCTTGGAGAA TGGCTTCTAC 
TCAGCCGAGG ACTTCCATGC GGGCAGCACG GTGACCTATC AGTGCACCAG TGGCTACTAC 
CTGCTGGGTG ATTCCCGAAT GTTCTGCACA GACAACGGGA GCTGGAACGG CATTTCACCA 
TCCTGTCTCG ATGTCGATGA GTGTGCAGTC GGCTCGGACT GTAGTGAGCA CGCCTCCTGC 
CTGAACACCA ACGGATCCTA CGTATGTTCC TGTAACCCAC CATACACGGG AGATGGGAAA 
AACTGTGCAG AACCTGTAAA ATGTAAGGCT CCAGAAAATC CAGAAAATGG CCACTCTTCT 
GGTGAGATTT ACACCGTGGG TACTGCAGTC ACATTTTCCT GTGACGAAGG GCACGAGCTG 
GTGGGAGTGA GCACCATCAC GTGTTTGGAG ACTGGCGAGT GGGATCGCCT CAGGCCGTCC 
TGTGAAGCCA TTTCCTGTGG TGTCCCACCT GTTCCTGAAA ATGGTGGTGT TGACGGGTCG 
GCATTCACAT ACGGCAGTAA GGTGGTGTAC AGGTGTGATA AAGGATATAC TTTGTCTGGG 
GATGAAGAGT CAGCATGCCT TGCTAGTGGT TCCTGGAGTC ATTCCTCTCC TGTGTGCGAG 
CTAGTGAAGT GTTCCCAGCC TGAGGACATA AATAACGGCA AATACATCTT AAGTGGGCTC 
ACCTACCTTT CTATTGCATC GTACTCCTGT GAGAACGGAT ACAGTTTACA GGGCCCATCC 
CTCCTTGAAT GCACAGCTTC CGGCAGCTGG GACAGAGCGC CACCTAGCTG TCAACTTGTC 
TCCTGCGGAG AGCCTCCAAT CGTCAAAGAT GCTGTCATCA CTGGGAGCAA CTTCACTTTT 
GGGAACACAG TTGCTTACAC ATGCAAAGAG GGCTACACCC TTGCTGGGCC TGACACCATC 
GTATGCCAGG CCAACGGCAA ATGGAATTCA AGTAACCACC AGTGCCTGGC TGTCTCCTGT 
GACGAGCCCC CCAATGTGGA CCACGCCTCT CCAGAGACTG CTCACAGGCT CTTTGGAGAC 
ACCGCGTTTT ACTACTGTGC GGATGGTTAC AGCCTGGCTG ATAATTCCCA GCTCATCTGC 
AATGCCCAGG GGAACTGGGT TCCCCCCGCG GGCCAGGCTG TGCCGCGCTG CATAGCTCAC 
TTCTGTGAAA AACCCCCATC TGTTTCCTAC AGCATCTTGG AATCTGTGAG CAAAGCAAAG 
TTTGCAGCTG GCTCGGTAGT GAGCTTCAAG TGCATGGAGG GTTTTGTGCT GAACACCTCA 
GCGAAGATTG AATGCCTGAG AGGTGGAGAG TGGAGCCCTT CTCCCCTCTC GGTCCAGTGC 
ATCCCGGTGC GATGCGGAGA GCCTCCAAGC ATCGCAAATG GCTACCCGAG TGGGACAAAC 
TACAGTTTTG GGGCCGTGGT GGCCTACAGC TGCCACAAGG GATTCTATAT CAAGGGGGAG 
AAGAAGAGCA CGTGTGAGGC CACAGGACAG TGGAGTAAAC CCACGCCCAC CTGCCATCCT 
GTGTCCTGTA ACGAGCCACC TAAGGTTGAG AACGGCTTCC TGGAGCACAC CACTGGCAGG 
ACCTTTGAGA GCGAAGCAAG GTTCCAGTGC AACCCAGGCT ATAAGGCAGC CGGAAGTCCT 
GTGTTTGTTT GCCAAGCCAA TCGCCACTGG CACAGCGACG CCCCTCTGTC CTGCACCCCT 
CTCAACTGTG GGAAACCCCC TCCCATTCAG AATGGCTTTT TGAAAGGAGA AAGCTTTGAA 
GTAGGGTCCA AGGTTCAGTT TGTCTGTAAT GAGGGATATG AGCTCGTTGG TGATAATTCT 
TGGACTTGCC AGAAATCTGG CAAATGGAGT AAGAAGCCAA GCCCGAAGTG TGTCCCCACC 
AAGTGTGCAG AGCCTCCTCT CTTAGAAAAC CAGCTCGTAT TGAAGGAATT AGCTTCCGAG 
GTAGGAGTGA TGACCATTTC CTGTAAAGAG GGGCATGCCT TGCAAGGCCC CTCTGTCCTG 
AAGTGCTTGC CATCCGGGCA ATGGAATGGT TCCTTTCCTA TTTGTAAGAT GGTCCTTTGT 
CCCTCGCCTC CCTTGATTCC CTTCGGCGTC CCTGCGTCTT CCGGTGCTCT TCATTTTGGC 
AGTACTGTCA AGTATCTGTG TGTCGACGGG TTTTTCTTAA GAGGCAGTCC AACCATCCTC 
TGCCAGGCTG ATAGCACCTG GAGTTCTCCA TTGCCCGAAT GCGTTCCGGT AGAATGTCCC 
CAACCTGAGG AGATCCTCAA CGGTATCATC CACGTACAAG GGCTTGCCTA TCTCAGCACC 
ACGCTCTACA CCTGCAAGCC AGGCTTTGAG TTAGTGGGCA ATGCTACCAC CCTCTGTGGG 
GAAAATGGCC AGTGGCTCGG AGGAAAACCA ATGTGCAAAC CCATTGAATG CCCAGAGCCC 
AAGGAGATTT TAAATGGCCA ATTCTCTTCC GTGAGCTTTC AGTATGGACA AACCATCACA 
TACTTTTGTG ACCGGGGCTT CCGGCTCGAA GGTCCCAAAT CCCTGACCTG TTTAGAGACA 
GGTGACTGGG ATATGGATCC CCCCTCTTGT GATGCCATCC ACTGCAGTGA CCCACAGCCC 
ATTGAAAATG GTTTCGTAGA AGGTGCGGAT TACAGATACG GTGCCATGAT CATCTATAGC 
TGCTTCCCTG GGTTTCAGGT GCTTGGTCAT GCCATGCAGA CCTGTGAAGA GTCGGGATGG 
TCAAGCTCCA GCCCAACCTG TGTACCCATA GACTGCGGTC TCCCTCCTCA CATAGACTTT 
GGTGACTGTA CTAAAGTCAG AGATGGCCAG GGACATTTTG ATCAAGAAGA TGACATGATG 
GAAGTCCCAT ATCTGGCTCA CCCTCAACAT TTGGAAGCAA CAGCTAAGGC CTTGGAAAAT 
ACAAAGGAGT CGCCTGCCTC ACATGCATCC CACTTCCTCT ATGGCACGAT GGTTTCCTAC 
AGCTGCGAGC CTGGTTATGA ACTGCTGGGA ATCCCTGTGC TGATCTGCCA GGAAGATGGT 
ACGTGGAATG GTACCGCACC CTCTTGCATT TCCATTGAAT GTGATTTGCC TGTTGCTCCC 
GAAAATGGCT TTTTACATTT CACACAGACG ACTATGGGCA GTGCTGCACA ATATAGCTGC 
AAGCCGGGGC ACATTCTAGA AGGCTCCCAC TTAAGACTCT GTCTGCAGAA TAAGCAGTGG 
AGTGGCACTG TTCCACGCTG TGAAGCCATC TCATGCAGTA AGCCAAACCC ACTCTGGAAT 
GGATCCATCA AAGGAGATGA CTACTCCTAC CTGGGTGTGT TATACTACGA GTGTGACTCT 
GGCTATATTC TCAATGGCTC TAAGAAGAGG ACATGCCAAG AAAATAGAGA TTGGGATGGG 
CATGAGCCCA TGTGTATTCC TGTAGACTGT GGCTCACCCC CAGTCCCCAC CAATGGCCGA 
GTGAAGGGAG AAGAATACAC ATTCCAAAAG GAGATTACAT ACTCTTGCCG TGAAGGGTTC 
ATACTGGAAG GAGCCAGGAG TCGTATCTGT CTTACCAATG GAAGTTGGAG TGGTGCCACT 
CCCAGCTGCA TGCCTGTTAG ATGTCCTGCC CCACCACAGG TGCCAAATGG GGTGGCAGAT 
GGCCTAGACT ATGGGTTCAA GAAGGAAGTA GCGTTCCACT GTCTAGAGGG CTATGTGCTG 
CAGGGGGCTC CAAGACTCAC CTGTCAGTCC AATGGGACTT GGGATGCAGA AGTCCCTGTC 
TGTAAACCAG CTACCTGTGG TCCTCCTGCC GACCTTCCCC AGGGCTTCCC TAATGGCTTT 
TCTTTTTATC ATGGGGGCCA CATACAGTAT CAGTGTTTTA CTGGTTATAA GCTTCATGGA 
AACCCATCAA GAAGATGCCT TCCCAATGGT TCCTGGAGCG GCAGCTCGCC ATCCTGCCTA 
CCTTGCAGGT GTTCCACACC CATCATTCAA CAGGGAACCA TCAACGCAAC TGATTTGGGA 
TGTGGAAAGA CGGTCCAGAT TGAGTGCTTC AAAGGCTTCA AGCTGCTTGG ACTTTCTGAA 
ATCACCTGTG ATGCCAATGG CCAATGGTCT GACGTCCCAC TGTGTGAGCA CGCTCAGTGC 
GGGCCTCTCC CAACCATACC CAACGCAATT GTCCTTGAGG GCAGCCTTTC GGAGGACAAT 
GTGGTAACTT ACAGCTGCAG ACCTGGCTAC ACCATGCAAG GTAGTTCAGA TCTGATTTGT 
ACGGAAAAAG CGATATGGAG CCAGCCTTAC CCAACGTGTG AACCCCTGTC CTGTGGACCC 
CCACCAACTG TAGCCAATGC AGTGGCAACA GGAGAGGCTC ATACCTATGA AAGCAAAGTG 
AAACTCAGGT GTCTGGAAGG GTATGTGATG GATTCGGATA CAGATACATT CACCTGCCAG 
CAAGATGGCC ATTGGGTCCC TGAAAGAATC ACCTGCAGTC CTAAAAAATG CCCTGTGCCA 
TCCAACATGA CACGCATACG TTTTCACGGA GATGACTTCC AGGTGAACAG ACAAGTTTCT 
GTGTCATGTG CAGAAGGGTT TACCCACGAA GGAGTGAACT GGTCAACATG CCAGCCCGAC 
GGTACATGGG AGCCACCATT TTCTGATGAA TCCTGTATCC CAGTTGTTTG TGGGCATCCT 
GAAAGCCCAG CGCATGGCTC CGTGGTTGGC AATAAGCACA GCTTTGGAAG CACCATTGTT 
TACCAGTGTG ACCCTGGCTA CAAATTAGAG GGGAACAGGG AACGAATCTG CCAGGAGAAC 
AGACAGTGGA GTGGAGAGGT GGCAGTGTGC AGAGAGAACA GATGTGAGAC TCCAGCTGAG 
TTTCCCAATG GGAAGGCTGT CTTGGAAAAC ACCACATCTG GACCCAGCCT TCTGTTTTCC 
TGTCACAGAG GCTACACCCT GGAAGGGTCC CCCGAGGCAC ACTGCACTGC AAATGGAACC 
TGGAATCACC TGACTCCCCT CTGCAAACCA AATCCATGCC CTGTCCCTTT TGTGATTCCT 
GAGAACGCCG TCCTTTCTGA AAAAGAGTTT TATGTCGACC AGAATGTATC TATCAAGTGC 
AGGGAAGGCT TCCTGCTCAA AGGCAATGGT GTCATCACGT GCAGCCCTGA CGAGACATGG 
ACGCACACCA ATGCCAGATG TGAAAAAATC TCCTGTGGTC CTCCAAGTCA CGTAGAGAAT 
GCAATTGCTC GAGGAGTGTA TTACCAGTAT GGGGACATGA TCACCTACTC CTGTTACAGT 
GGCTACATGC TAGAAGGTTC CCTCCGGAGT GTTTGCCTAG AAAATGGAAC ATGGACACCA 
TCTCCTGTTT GCAGAGCTGT CTGTCGGTTC CCATGTCAGA ATGGAGGTGT CTGTCAACGT 
CCAAATGCTT GCTCATGCCC AGACGGCTGG ATGGGACGTC TCTGTGAAGA GCCAATATGC 
ATACTCCCCT GTTTGAATGG TGGGCGCTGT GTGGCCCCTT ATCAGTGTGA CTGCCCCACA 
GGCTGGACTG GGTCCCGCTG TCATACAGCT ACTTGTCAGT CCCCCTGCTT AAATGGCGGG 
AAATGCATAA GACCAAACCG ATGCCATTGT CTCTCAGCCT GGACAGGACA TGATTGTTCC 
AGGAAAAGGA GAGCCGGGCT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SVEP1 plays a crucial role in epidermal differentiation.
Experimental dermatology26(5)423-430(2017 May)
Samuelov L,Li Q,Bochner R,Najor NA,Albrecht L,Malchin N,Goldsmith T,Grafi-Cohen M,Vodo D,Fainberg G,Meilik B,Goldberg I,Warshauer E,Rogers T,Edie S,Ishida-Yamamoto A,Burzenski L,Erez N,Murray SA,Irvine AD,Shultz L,Green KJ,Uitto J,Sprecher E,Sarig O

An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation.
Circulation research120(8)1263-1275(2017 Apr)
Karpanen T,Padberg Y,van de Pavert SA,Dierkes C,Morooka N,Peterson-Maduro J,van de Hoek G,Adrian M,Mochizuki N,Sekiguchi K,Kiefer F,Schulte D,Schulte-Merker S

Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling.
Circulation research120(8)1276-1288(2017 Apr)
Morooka N,Futaki S,Sato-Nishiuchi R,Nishino M,Totani Y,Shimono C,Nakano I,Nakajima H,Mochizuki N,Sekiguchi K

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
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Spatiotemporal regulation of GLI target genes in the mammalian limb bud.
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