Extl2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Extl2
Entrez Gene ID	58193
Full Name	exostoses (multiple)-like 2
Synonyms	3000001D04Rik,AW146439
General protein information	Preferred Names exostoses (multiple)-like 2 Names exostosin-like 2 EXT-related protein 2 alpha-1,4-N-acetylhexosaminyltransferase EXTL2 alpha-GalNAcT EXTL2 exostoses-like 2 exotoses (multiple)-like 2 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 3 Map Location: 3\|3 G1

mRNA and Protein(s)

mRNA	Protein	Name
XM_011240177.3	XP_011238479.1	exostosin-like 2 isoform X1
NM_001163515.1	NP_001156987.1	exostosin-like 2 isoform b precursor
NM_021388.4	NP_067363.3	exostosin-like 2 isoform a
XM_011240177.2	XP_011238479.1	exostosin-like 2 isoform X1
XM_030252739.1	XP_030108599.1	exostosin-like 2 isoform X2
XM_006501827.3	XP_006501890.1	exostosin-like 2 isoform X2
XM_017319674.1	XP_017175163.1	exostosin-like 2 isoform X1
NM_001163514.1	NP_001156986.1	exostosin-like 2 isoform a

Pathways from BioSystems

Homologies

	EXTL2	XP_001108303.2
Canis lupus familiaris (dog)	EXTL2	XP_005621917.1
Bos taurus (cattle)	EXTL2	NP_001069692.1
Gallus gallus (chicken)	EXTL2	XP_422308.2
Danio rerio (zebrafish)	extl2	NP_001070029.1
Homo sapiens (human)	EXTL2	NP_001430.1
Rattus norvegicus (Norway rat)	Extl2	NP_001094174.1
Xenopus tropicalis (tropical clawed frog)	extl2	NP_001007952.1
Arabidopsis thaliana (thale cress)	EPC1	NP_191142.1
Pan troglodytes (chimpanzee)	EXTL2	XP_513595.1
Mus musculus (house mouse)	Extl2	NP_001156986.1

Gene Ontology
Bibliography

Related articles in PubMed

Exostosin-like 2 regulates FGF2 signaling by controlling the endocytosis of FGF2.
Nadanaka S, Kitagawa H
Biochimica et biophysica acta1862(4)791-799(2018 Jan)

EXTL2 controls liver regeneration and aortic calcification through xylose kinase-dependent regulation of glycosaminoglycan biosynthesis.
Nadanaka S, Kitagawa H
Matrix biology : journal of the International Society for Matrix Biology3518-24(2014 Apr)

Roles of EXTL2, a member of the EXT family of tumour suppressors, in liver injury and regeneration processes.
Nadanaka S, Kagiyama S, Kitagawa H
The Biochemical journal454(1)133-45(2013 Aug)

EXTL2, a member of the EXT family of tumor suppressors, controls glycosaminoglycan biosynthesis in a xylose kinase-dependent manner.
Nadanaka S, Zhou S, Kagiyama S, Shoji N, Sugahara K, Sugihara K, Asano M, Kitagawa H
The Journal of biological chemistry288(13)9321-33(2013 Mar)

Crystal structure of an alpha 1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis.
Pedersen LC, Dong J, Taniguchi F, Kitagawa H, Krahn JM, Pedersen LG, Sugahara K, Negishi M
The Journal of biological chemistry278(16)14420-8(2003 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

EXTL2 controls liver regeneration and aortic calcification through xylose kinase-dependent regulation of glycosaminoglycan biosynthesis.[review]
Title: EXTL2 controls liver regeneration and aortic calcification through xylose kinase-dependent regulation of glycosaminoglycan biosynthesis.

EXTL2-mediated regulation of glycosaminoglycans synthesis is important for tissue regeneration processes following liver injury.
Title: Roles of EXTL2, a member of the EXT family of tumour suppressors, in liver injury and regeneration processes.

EXTL2 functions to suppress GAG biosynthesis that is enhanced by a xylose kinase and the EXTL2-dependent mechanism that regulates GAG biosynthesis might be a "quality control system" for proteoglycans
Title: EXTL2, a member of the EXT family of tumor suppressors, controls glycosaminoglycan biosynthesis in a xylose kinase-dependent manner.

crystal structure of EXTL2
Title: Crystal structure of an alpha 1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis.

The following Extl2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Extl2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu18896	NM_021388.4 Latest version!	Mus musculus exostosin-like glycosyltransferase 2 (Extl2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu18896	NM_001163514.1 Latest version!	Mus musculus exostosin-like glycosyltransferase 2 (Extl2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu19025	NM_001163515.1 Latest version!	Mus musculus exostosin-like glycosyltransferase 2 (Extl2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu19025	XM_006501827.3 Latest version!	Mus musculus exostoses (multiple)-like 2 (Extl2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu69770	XM_017319674.1 Latest version!	Mus musculus exostoses (multiple)-like 2 (Extl2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu19025	XM_030252739.1 Latest version!	Mus musculus exostoses (multiple)-like 2 (Extl2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu69770	XM_011240177.3 Latest version!	Mus musculus exostoses (multiple)-like 2 (Extl2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu69770	XM_011240177.2	Mus musculus exostoses (multiple)-like 2 (Extl2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Extl2 ( NM_021388.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_067363.3 Mus musculus exostosin-like glycosyltransferase 2 (Extl2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu18896
Clone ID Related Accession (Same CDS sequence)	NM_021388.4 , NM_001163514.1
Accession Version	NM_021388.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 993bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-02
Organism	Mus musculus(house mouse)
Product	exostosin-like 2 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BG694725.1, BC094444.1 and AK032016.1. On Jul 22, 2009 this sequence version replaced NM_021388.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode the same isoform. ##Evidence-Data-START## Transcript exon combination :: AB032170.1, SRR1660821.53947.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGAGGG GTTGCCACAT CTGCAAACTT CCGGGAAGAG TCATGGGGAT TCGAGTGCTC 
CGGTTCTCCC TGGTGGTCAT CCTTGTGTTG CTGCTGGTAG CGGGGGCTTT GACCAACTTA 
CTCCCCAACA TCAAAGAAGA CAAGATGCTC ACTCTGCGTA GGGAGATCAA ATCCCCGAGC 
AAGTCGGCCC TGGATTCATT CACCCTCATC ATGCAGACAT ACAACAGAAC AGACCTCTTA 
CTAAGACTCT TAAATCATTA CCAGGCAGTA CCGAGTCTGC ACAAGGTGAT CGTGGTGTGG 
AACAATGTGG GAGAGAAGGG CCCAGAGGAG TTGTGGAATT CTCTAGGGCC TCACCCGATC 
CCTGTCATCT TCAAACCACA AACAGCAAAC AAAATGAGAA ACCGACTCCA GGTCTTCCCT 
GAAGTGGAGA CCAACGCGGT GTTGATGGTA GACGATGACA CACTCATTAG TGCCCAGGAC 
CTTGTTTTCG CTTTCTCAAT TTGGCAGCAA TTTCCTGATC AGATCATAGG ATTTGTACCT 
AGAAAGCACG TCTCTACTTC CTCCGGGATC TACAGTTACG GAGGCTTTGA GCTGCAGACA 
CCGGGGCCCG GGAATGGCGA CCAGTACTCC ATGGTGCTCA TCGGAGCCTC CTTCTTCAAC 
AGCAAATACC TGGAACTCTT CCAGAAGCAG CCTGCAGCCG TCCACGCGCT GATCGATGAG 
ACGCAGAACT GTGACGACAT CGCTATGAAT TTCCTCGTCA CCAGGCACAC TGGCAAGCCT 
TCAGGGATAT TCGTGAAACC CATAAACATG GTCAACTTGG AAAAAGAAAC CAACGGGTAT 
TCCGGAATGT GGCACCGGGC GGAGCACTTT CTGCAGAGAT CCTACTGTAT AAATAAGCTC 
GTTAACATCT ACGACGGCAT GCCCTTAAAG TACTCCAACA TTATGATTTC CCAGTTTGGT 
TTTCCGTATG CCAACCATAA AAGTAAAATG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067363.3
CDS	502..1494
Translation	MMRGCHICKLPGRVMGIRVLRFSLVVILVLLLVAGALTNLLPNIKEDKMLTLRREIKSPSKSALDSFTLIMQTYNRTDLLLRLLNHYQAVPSLHKVIVVWNNVGEKGPEELWNSLGPHPIPVIFKPQTANKMRNRLQVFPEVETNAVLMVDDDTLISAQDLVFAFSIWQQFPDQIIGFVPRKHVSTSSGIYSYGGFELQTPGPGNGDQYSMVLIGASFFNSKYLELFQKQPAAVHALIDETQNCDDIAMNFLVTRHTGKPSGIFVKPINMVNLEKETNGYSGMWHRAEHFLQRSYCINKLVNIYDGMPLKYSNIMISQFGFPYANHKSKM

Target ORF information:

RefSeq Version	NM_021388.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus exostosin-like glycosyltransferase 2 (Extl2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021388.4

ORF Insert Sequence:

ATGATGAGGG GTTGCCACAT CTGCAAACTT CCGGGAAGAG TCATGGGGAT TCGAGTGCTC 
CGGTTCTCCC TGGTGGTCAT CCTTGTGTTG CTGCTGGTAG CGGGGGCTTT GACCAACTTA 
CTCCCCAACA TCAAAGAAGA CAAGATGCTC ACTCTGCGTA GGGAGATCAA ATCCCCGAGC 
AAGTCGGCCC TGGATTCATT CACCCTCATC ATGCAGACAT ACAACAGAAC AGACCTCTTA 
CTAAGACTCT TAAATCATTA CCAGGCAGTA CCGAGTCTGC ACAAGGTGAT CGTGGTGTGG 
AACAATGTGG GAGAGAAGGG CCCAGAGGAG TTGTGGAATT CTCTAGGGCC TCACCCGATC 
CCTGTCATCT TCAAACCACA AACAGCAAAC AAAATGAGAA ACCGACTCCA GGTCTTCCCT 
GAAGTGGAGA CCAACGCGGT GTTGATGGTA GACGATGACA CACTCATTAG TGCCCAGGAC 
CTTGTTTTCG CTTTCTCAAT TTGGCAGCAA TTTCCTGATC AGATCATAGG ATTTGTACCT 
AGAAAGCACG TCTCTACTTC CTCCGGGATC TACAGTTACG GAGGCTTTGA GCTGCAGACA 
CCGGGGCCCG GGAATGGCGA CCAGTACTCC ATGGTGCTCA TCGGAGCCTC CTTCTTCAAC 
AGCAAATACC TGGAACTCTT CCAGAAGCAG CCTGCAGCCG TCCACGCGCT GATCGATGAG 
ACGCAGAACT GTGACGACAT CGCTATGAAT TTCCTCGTCA CCAGGCACAC TGGCAAGCCT 
TCAGGGATAT TCGTGAAACC CATAAACATG GTCAACTTGG AAAAAGAAAC CAACGGGTAT 
TCCGGAATGT GGCACCGGGC GGAGCACTTT CTGCAGAGAT CCTACTGTAT AAATAAGCTC 
GTTAACATCT ACGACGGCAT GCCCTTAAAG TACTCCAACA TTATGATTTC CCAGTTTGGT 
TTTCCGTATG CCAACCATAA AAGTAAAATG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Extl2 ( NM_001163514.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001156986.1 Mus musculus exostosin-like glycosyltransferase 2 (Extl2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu18896
Clone ID Related Accession (Same CDS sequence)	NM_021388.4 , NM_001163514.1
Accession Version	NM_001163514.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 993bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-02
Organism	Mus musculus(house mouse)
Product	exostosin-like 2 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY251302.1, AK019370.1, BC094444.1 and AK032016.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a). ##Evidence-Data-START## Transcript exon combination :: AB032171.1, SRR1660811.219350.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGAGGG GTTGCCACAT CTGCAAACTT CCGGGAAGAG TCATGGGGAT TCGAGTGCTC 
CGGTTCTCCC TGGTGGTCAT CCTTGTGTTG CTGCTGGTAG CGGGGGCTTT GACCAACTTA 
CTCCCCAACA TCAAAGAAGA CAAGATGCTC ACTCTGCGTA GGGAGATCAA ATCCCCGAGC 
AAGTCGGCCC TGGATTCATT CACCCTCATC ATGCAGACAT ACAACAGAAC AGACCTCTTA 
CTAAGACTCT TAAATCATTA CCAGGCAGTA CCGAGTCTGC ACAAGGTGAT CGTGGTGTGG 
AACAATGTGG GAGAGAAGGG CCCAGAGGAG TTGTGGAATT CTCTAGGGCC TCACCCGATC 
CCTGTCATCT TCAAACCACA AACAGCAAAC AAAATGAGAA ACCGACTCCA GGTCTTCCCT 
GAAGTGGAGA CCAACGCGGT GTTGATGGTA GACGATGACA CACTCATTAG TGCCCAGGAC 
CTTGTTTTCG CTTTCTCAAT TTGGCAGCAA TTTCCTGATC AGATCATAGG ATTTGTACCT 
AGAAAGCACG TCTCTACTTC CTCCGGGATC TACAGTTACG GAGGCTTTGA GCTGCAGACA 
CCGGGGCCCG GGAATGGCGA CCAGTACTCC ATGGTGCTCA TCGGAGCCTC CTTCTTCAAC 
AGCAAATACC TGGAACTCTT CCAGAAGCAG CCTGCAGCCG TCCACGCGCT GATCGATGAG 
ACGCAGAACT GTGACGACAT CGCTATGAAT TTCCTCGTCA CCAGGCACAC TGGCAAGCCT 
TCAGGGATAT TCGTGAAACC CATAAACATG GTCAACTTGG AAAAAGAAAC CAACGGGTAT 
TCCGGAATGT GGCACCGGGC GGAGCACTTT CTGCAGAGAT CCTACTGTAT AAATAAGCTC 
GTTAACATCT ACGACGGCAT GCCCTTAAAG TACTCCAACA TTATGATTTC CCAGTTTGGT 
TTTCCGTATG CCAACCATAA AAGTAAAATG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001156986.1
CDS	309..1301
Translation	MMRGCHICKLPGRVMGIRVLRFSLVVILVLLLVAGALTNLLPNIKEDKMLTLRREIKSPSKSALDSFTLIMQTYNRTDLLLRLLNHYQAVPSLHKVIVVWNNVGEKGPEELWNSLGPHPIPVIFKPQTANKMRNRLQVFPEVETNAVLMVDDDTLISAQDLVFAFSIWQQFPDQIIGFVPRKHVSTSSGIYSYGGFELQTPGPGNGDQYSMVLIGASFFNSKYLELFQKQPAAVHALIDETQNCDDIAMNFLVTRHTGKPSGIFVKPINMVNLEKETNGYSGMWHRAEHFLQRSYCINKLVNIYDGMPLKYSNIMISQFGFPYANHKSKM

Target ORF information:

RefSeq Version	NM_001163514.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus exostosin-like glycosyltransferase 2 (Extl2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001163514.1

ORF Insert Sequence:

ATGATGAGGG GTTGCCACAT CTGCAAACTT CCGGGAAGAG TCATGGGGAT TCGAGTGCTC 
CGGTTCTCCC TGGTGGTCAT CCTTGTGTTG CTGCTGGTAG CGGGGGCTTT GACCAACTTA 
CTCCCCAACA TCAAAGAAGA CAAGATGCTC ACTCTGCGTA GGGAGATCAA ATCCCCGAGC 
AAGTCGGCCC TGGATTCATT CACCCTCATC ATGCAGACAT ACAACAGAAC AGACCTCTTA 
CTAAGACTCT TAAATCATTA CCAGGCAGTA CCGAGTCTGC ACAAGGTGAT CGTGGTGTGG 
AACAATGTGG GAGAGAAGGG CCCAGAGGAG TTGTGGAATT CTCTAGGGCC TCACCCGATC 
CCTGTCATCT TCAAACCACA AACAGCAAAC AAAATGAGAA ACCGACTCCA GGTCTTCCCT 
GAAGTGGAGA CCAACGCGGT GTTGATGGTA GACGATGACA CACTCATTAG TGCCCAGGAC 
CTTGTTTTCG CTTTCTCAAT TTGGCAGCAA TTTCCTGATC AGATCATAGG ATTTGTACCT 
AGAAAGCACG TCTCTACTTC CTCCGGGATC TACAGTTACG GAGGCTTTGA GCTGCAGACA 
CCGGGGCCCG GGAATGGCGA CCAGTACTCC ATGGTGCTCA TCGGAGCCTC CTTCTTCAAC 
AGCAAATACC TGGAACTCTT CCAGAAGCAG CCTGCAGCCG TCCACGCGCT GATCGATGAG 
ACGCAGAACT GTGACGACAT CGCTATGAAT TTCCTCGTCA CCAGGCACAC TGGCAAGCCT 
TCAGGGATAT TCGTGAAACC CATAAACATG GTCAACTTGG AAAAAGAAAC CAACGGGTAT 
TCCGGAATGT GGCACCGGGC GGAGCACTTT CTGCAGAGAT CCTACTGTAT AAATAAGCTC 
GTTAACATCT ACGACGGCAT GCCCTTAAAG TACTCCAACA TTATGATTTC CCAGTTTGGT 
TTTCCGTATG CCAACCATAA AAGTAAAATG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Extl2 ( NM_001163515.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001156987.1 Mus musculus exostosin-like glycosyltransferase 2 (Extl2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu19025
Clone ID Related Accession (Same CDS sequence)	NM_001163515.1 , XM_030252739.1 , XM_006501827.3
Accession Version	NM_001163515.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 951bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-02
Organism	Mus musculus(house mouse)
Product	exostosin-like 2 isoform b precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BG694725.1, AK161866.1 and AK032016.1. Transcript Variant: This variant (3) lacks the alternate exon containing the translation start codon compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. ##Evidence-Data-START## Transcript exon combination :: AK161866.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGATTC GAGTGCTCCG GTTCTCCCTG GTGGTCATCC TTGTGTTGCT GCTGGTAGCG 
GGGGCTTTGA CCAACTTACT CCCCAACATC AAAGAAGACA AGATGCTCAC TCTGCGTAGG 
GAGATCAAAT CCCCGAGCAA GTCGGCCCTG GATTCATTCA CCCTCATCAT GCAGACATAC 
AACAGAACAG ACCTCTTACT AAGACTCTTA AATCATTACC AGGCAGTACC GAGTCTGCAC 
AAGGTGATCG TGGTGTGGAA CAATGTGGGA GAGAAGGGCC CAGAGGAGTT GTGGAATTCT 
CTAGGGCCTC ACCCGATCCC TGTCATCTTC AAACCACAAA CAGCAAACAA AATGAGAAAC 
CGACTCCAGG TCTTCCCTGA AGTGGAGACC AACGCGGTGT TGATGGTAGA CGATGACACA 
CTCATTAGTG CCCAGGACCT TGTTTTCGCT TTCTCAATTT GGCAGCAATT TCCTGATCAG 
ATCATAGGAT TTGTACCTAG AAAGCACGTC TCTACTTCCT CCGGGATCTA CAGTTACGGA 
GGCTTTGAGC TGCAGACACC GGGGCCCGGG AATGGCGACC AGTACTCCAT GGTGCTCATC 
GGAGCCTCCT TCTTCAACAG CAAATACCTG GAACTCTTCC AGAAGCAGCC TGCAGCCGTC 
CACGCGCTGA TCGATGAGAC GCAGAACTGT GACGACATCG CTATGAATTT CCTCGTCACC 
AGGCACACTG GCAAGCCTTC AGGGATATTC GTGAAACCCA TAAACATGGT CAACTTGGAA 
AAAGAAACCA ACGGGTATTC CGGAATGTGG CACCGGGCGG AGCACTTTCT GCAGAGATCC 
TACTGTATAA ATAAGCTCGT TAACATCTAC GACGGCATGC CCTTAAAGTA CTCCAACATT 
ATGATTTCCC AGTTTGGTTT TCCGTATGCC AACCATAAAA GTAAAATGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001156987.1
CDS	469..1419
Translation	MGIRVLRFSLVVILVLLLVAGALTNLLPNIKEDKMLTLRREIKSPSKSALDSFTLIMQTYNRTDLLLRLLNHYQAVPSLHKVIVVWNNVGEKGPEELWNSLGPHPIPVIFKPQTANKMRNRLQVFPEVETNAVLMVDDDTLISAQDLVFAFSIWQQFPDQIIGFVPRKHVSTSSGIYSYGGFELQTPGPGNGDQYSMVLIGASFFNSKYLELFQKQPAAVHALIDETQNCDDIAMNFLVTRHTGKPSGIFVKPINMVNLEKETNGYSGMWHRAEHFLQRSYCINKLVNIYDGMPLKYSNIMISQFGFPYANHKSKM

Target ORF information:

RefSeq Version	NM_001163515.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus exostosin-like glycosyltransferase 2 (Extl2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001163515.1

ORF Insert Sequence:

ATGGGGATTC GAGTGCTCCG GTTCTCCCTG GTGGTCATCC TTGTGTTGCT GCTGGTAGCG 
GGGGCTTTGA CCAACTTACT CCCCAACATC AAAGAAGACA AGATGCTCAC TCTGCGTAGG 
GAGATCAAAT CCCCGAGCAA GTCGGCCCTG GATTCATTCA CCCTCATCAT GCAGACATAC 
AACAGAACAG ACCTCTTACT AAGACTCTTA AATCATTACC AGGCAGTACC GAGTCTGCAC 
AAGGTGATCG TGGTGTGGAA CAATGTGGGA GAGAAGGGCC CAGAGGAGTT GTGGAATTCT 
CTAGGGCCTC ACCCGATCCC TGTCATCTTC AAACCACAAA CAGCAAACAA AATGAGAAAC 
CGACTCCAGG TCTTCCCTGA AGTGGAGACC AACGCGGTGT TGATGGTAGA CGATGACACA 
CTCATTAGTG CCCAGGACCT TGTTTTCGCT TTCTCAATTT GGCAGCAATT TCCTGATCAG 
ATCATAGGAT TTGTACCTAG AAAGCACGTC TCTACTTCCT CCGGGATCTA CAGTTACGGA 
GGCTTTGAGC TGCAGACACC GGGGCCCGGG AATGGCGACC AGTACTCCAT GGTGCTCATC 
GGAGCCTCCT TCTTCAACAG CAAATACCTG GAACTCTTCC AGAAGCAGCC TGCAGCCGTC 
CACGCGCTGA TCGATGAGAC GCAGAACTGT GACGACATCG CTATGAATTT CCTCGTCACC 
AGGCACACTG GCAAGCCTTC AGGGATATTC GTGAAACCCA TAAACATGGT CAACTTGGAA 
AAAGAAACCA ACGGGTATTC CGGAATGTGG CACCGGGCGG AGCACTTTCT GCAGAGATCC 
TACTGTATAA ATAAGCTCGT TAACATCTAC GACGGCATGC CCTTAAAGTA CTCCAACATT 
ATGATTTCCC AGTTTGGTTT TCCGTATGCC AACCATAAAA GTAAAATGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Extl2 ( XM_006501827.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006501890.1 Mus musculus exostoses (multiple)-like 2 (Extl2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu19025
Clone ID Related Accession (Same CDS sequence)	NM_001163515.1 , XM_030252739.1 , XM_006501827.3
Accession Version	XM_006501827.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 951bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	exostosin-like 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000069.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006501827.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGATTC GAGTGCTCCG GTTCTCCCTG GTGGTCATCC TTGTGTTGCT GCTGGTAGCG 
GGGGCTTTGA CCAACTTACT CCCCAACATC AAAGAAGACA AGATGCTCAC TCTGCGTAGG 
GAGATCAAAT CCCCGAGCAA GTCGGCCCTG GATTCATTCA CCCTCATCAT GCAGACATAC 
AACAGAACAG ACCTCTTACT AAGACTCTTA AATCATTACC AGGCAGTACC GAGTCTGCAC 
AAGGTGATCG TGGTGTGGAA CAATGTGGGA GAGAAGGGCC CAGAGGAGTT GTGGAATTCT 
CTAGGGCCTC ACCCGATCCC TGTCATCTTC AAACCACAAA CAGCAAACAA AATGAGAAAC 
CGACTCCAGG TCTTCCCTGA AGTGGAGACC AACGCGGTGT TGATGGTAGA CGATGACACA 
CTCATTAGTG CCCAGGACCT TGTTTTCGCT TTCTCAATTT GGCAGCAATT TCCTGATCAG 
ATCATAGGAT TTGTACCTAG AAAGCACGTC TCTACTTCCT CCGGGATCTA CAGTTACGGA 
GGCTTTGAGC TGCAGACACC GGGGCCCGGG AATGGCGACC AGTACTCCAT GGTGCTCATC 
GGAGCCTCCT TCTTCAACAG CAAATACCTG GAACTCTTCC AGAAGCAGCC TGCAGCCGTC 
CACGCGCTGA TCGATGAGAC GCAGAACTGT GACGACATCG CTATGAATTT CCTCGTCACC 
AGGCACACTG GCAAGCCTTC AGGGATATTC GTGAAACCCA TAAACATGGT CAACTTGGAA 
AAAGAAACCA ACGGGTATTC CGGAATGTGG CACCGGGCGG AGCACTTTCT GCAGAGATCC 
TACTGTATAA ATAAGCTCGT TAACATCTAC GACGGCATGC CCTTAAAGTA CTCCAACATT 
ATGATTTCCC AGTTTGGTTT TCCGTATGCC AACCATAAAA GTAAAATGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006501890.1
CDS	131..1081
Translation	MGIRVLRFSLVVILVLLLVAGALTNLLPNIKEDKMLTLRREIKSPSKSALDSFTLIMQTYNRTDLLLRLLNHYQAVPSLHKVIVVWNNVGEKGPEELWNSLGPHPIPVIFKPQTANKMRNRLQVFPEVETNAVLMVDDDTLISAQDLVFAFSIWQQFPDQIIGFVPRKHVSTSSGIYSYGGFELQTPGPGNGDQYSMVLIGASFFNSKYLELFQKQPAAVHALIDETQNCDDIAMNFLVTRHTGKPSGIFVKPINMVNLEKETNGYSGMWHRAEHFLQRSYCINKLVNIYDGMPLKYSNIMISQFGFPYANHKSKM

Target ORF information:

RefSeq Version	XM_006501827.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus exostoses (multiple)-like 2 (Extl2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006501827.3

ORF Insert Sequence:

ATGGGGATTC GAGTGCTCCG GTTCTCCCTG GTGGTCATCC TTGTGTTGCT GCTGGTAGCG 
GGGGCTTTGA CCAACTTACT CCCCAACATC AAAGAAGACA AGATGCTCAC TCTGCGTAGG 
GAGATCAAAT CCCCGAGCAA GTCGGCCCTG GATTCATTCA CCCTCATCAT GCAGACATAC 
AACAGAACAG ACCTCTTACT AAGACTCTTA AATCATTACC AGGCAGTACC GAGTCTGCAC 
AAGGTGATCG TGGTGTGGAA CAATGTGGGA GAGAAGGGCC CAGAGGAGTT GTGGAATTCT 
CTAGGGCCTC ACCCGATCCC TGTCATCTTC AAACCACAAA CAGCAAACAA AATGAGAAAC 
CGACTCCAGG TCTTCCCTGA AGTGGAGACC AACGCGGTGT TGATGGTAGA CGATGACACA 
CTCATTAGTG CCCAGGACCT TGTTTTCGCT TTCTCAATTT GGCAGCAATT TCCTGATCAG 
ATCATAGGAT TTGTACCTAG AAAGCACGTC TCTACTTCCT CCGGGATCTA CAGTTACGGA 
GGCTTTGAGC TGCAGACACC GGGGCCCGGG AATGGCGACC AGTACTCCAT GGTGCTCATC 
GGAGCCTCCT TCTTCAACAG CAAATACCTG GAACTCTTCC AGAAGCAGCC TGCAGCCGTC 
CACGCGCTGA TCGATGAGAC GCAGAACTGT GACGACATCG CTATGAATTT CCTCGTCACC 
AGGCACACTG GCAAGCCTTC AGGGATATTC GTGAAACCCA TAAACATGGT CAACTTGGAA 
AAAGAAACCA ACGGGTATTC CGGAATGTGG CACCGGGCGG AGCACTTTCT GCAGAGATCC 
TACTGTATAA ATAAGCTCGT TAACATCTAC GACGGCATGC CCTTAAAGTA CTCCAACATT 
ATGATTTCCC AGTTTGGTTT TCCGTATGCC AACCATAAAA GTAAAATGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Extl2 ( XM_011240177.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011238479.1 Mus musculus exostoses (multiple)-like 2 (Extl2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu69770
Clone ID Related Accession (Same CDS sequence)	XM_011240177.3 , XM_011240177.2 , XM_017319674.1
Accession Version	XM_011240177.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 987bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	exostosin-like 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000069.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011240177.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTTGCC ACATCTGCAA ACTTCCGGGA AGAGTCATGG GGATTCGAGT GCTCCGGTTC 
TCCCTGGTGG TCATCCTTGT GTTGCTGCTG GTAGCGGGGG CTTTGACCAA CTTACTCCCC 
AACATCAAAG AAGACAAGAT GCTCACTCTG CGTAGGGAGA TCAAATCCCC GAGCAAGTCG 
GCCCTGGATT CATTCACCCT CATCATGCAG ACATACAACA GAACAGACCT CTTACTAAGA 
CTCTTAAATC ATTACCAGGC AGTACCGAGT CTGCACAAGG TGATCGTGGT GTGGAACAAT 
GTGGGAGAGA AGGGCCCAGA GGAGTTGTGG AATTCTCTAG GGCCTCACCC GATCCCTGTC 
ATCTTCAAAC CACAAACAGC AAACAAAATG AGAAACCGAC TCCAGGTCTT CCCTGAAGTG 
GAGACCAACG CGGTGTTGAT GGTAGACGAT GACACACTCA TTAGTGCCCA GGACCTTGTT 
TTCGCTTTCT CAATTTGGCA GCAATTTCCT GATCAGATCA TAGGATTTGT ACCTAGAAAG 
CACGTCTCTA CTTCCTCCGG GATCTACAGT TACGGAGGCT TTGAGCTGCA GACACCGGGG 
CCCGGGAATG GCGACCAGTA CTCCATGGTG CTCATCGGAG CCTCCTTCTT CAACAGCAAA 
TACCTGGAAC TCTTCCAGAA GCAGCCTGCA GCCGTCCACG CGCTGATCGA TGAGACGCAG 
AACTGTGACG ACATCGCTAT GAATTTCCTC GTCACCAGGC ACACTGGCAA GCCTTCAGGG 
ATATTCGTGA AACCCATAAA CATGGTCAAC TTGGAAAAAG AAACCAACGG GTATTCCGGA 
ATGTGGCACC GGGCGGAGCA CTTTCTGCAG AGATCCTACT GTATAAATAA GCTCGTTAAC 
ATCTACGACG GCATGCCCTT AAAGTACTCC AACATTATGA TTTCCCAGTT TGGTTTTCCG 
TATGCCAACC ATAAAAGTAA AATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011238479.1
CDS	600..1586
Translation	MGCHICKLPGRVMGIRVLRFSLVVILVLLLVAGALTNLLPNIKEDKMLTLRREIKSPSKSALDSFTLIMQTYNRTDLLLRLLNHYQAVPSLHKVIVVWNNVGEKGPEELWNSLGPHPIPVIFKPQTANKMRNRLQVFPEVETNAVLMVDDDTLISAQDLVFAFSIWQQFPDQIIGFVPRKHVSTSSGIYSYGGFELQTPGPGNGDQYSMVLIGASFFNSKYLELFQKQPAAVHALIDETQNCDDIAMNFLVTRHTGKPSGIFVKPINMVNLEKETNGYSGMWHRAEHFLQRSYCINKLVNIYDGMPLKYSNIMISQFGFPYANHKSKM

Target ORF information:

RefSeq Version	XM_011240177.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus exostoses (multiple)-like 2 (Extl2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011240177.2

ORF Insert Sequence:

ATGGGTTGCC ACATCTGCAA ACTTCCGGGA AGAGTCATGG GGATTCGAGT GCTCCGGTTC 
TCCCTGGTGG TCATCCTTGT GTTGCTGCTG GTAGCGGGGG CTTTGACCAA CTTACTCCCC 
AACATCAAAG AAGACAAGAT GCTCACTCTG CGTAGGGAGA TCAAATCCCC GAGCAAGTCG 
GCCCTGGATT CATTCACCCT CATCATGCAG ACATACAACA GAACAGACCT CTTACTAAGA 
CTCTTAAATC ATTACCAGGC AGTACCGAGT CTGCACAAGG TGATCGTGGT GTGGAACAAT 
GTGGGAGAGA AGGGCCCAGA GGAGTTGTGG AATTCTCTAG GGCCTCACCC GATCCCTGTC 
ATCTTCAAAC CACAAACAGC AAACAAAATG AGAAACCGAC TCCAGGTCTT CCCTGAAGTG 
GAGACCAACG CGGTGTTGAT GGTAGACGAT GACACACTCA TTAGTGCCCA GGACCTTGTT 
TTCGCTTTCT CAATTTGGCA GCAATTTCCT GATCAGATCA TAGGATTTGT ACCTAGAAAG 
CACGTCTCTA CTTCCTCCGG GATCTACAGT TACGGAGGCT TTGAGCTGCA GACACCGGGG 
CCCGGGAATG GCGACCAGTA CTCCATGGTG CTCATCGGAG CCTCCTTCTT CAACAGCAAA 
TACCTGGAAC TCTTCCAGAA GCAGCCTGCA GCCGTCCACG CGCTGATCGA TGAGACGCAG 
AACTGTGACG ACATCGCTAT GAATTTCCTC GTCACCAGGC ACACTGGCAA GCCTTCAGGG 
ATATTCGTGA AACCCATAAA CATGGTCAAC TTGGAAAAAG AAACCAACGG GTATTCCGGA 
ATGTGGCACC GGGCGGAGCA CTTTCTGCAG AGATCCTACT GTATAAATAA GCTCGTTAAC 
ATCTACGACG GCATGCCCTT AAAGTACTCC AACATTATGA TTTCCCAGTT TGGTTTTCCG 
TATGCCAACC ATAAAAGTAA AATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Extl2 ( XM_017319674.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017175163.1 Mus musculus exostoses (multiple)-like 2 (Extl2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu69770
Clone ID Related Accession (Same CDS sequence)	XM_011240177.3 , XM_011240177.2 , XM_017319674.1
Accession Version	XM_017319674.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 987bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	exostosin-like 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000069.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTTGCC ACATCTGCAA ACTTCCGGGA AGAGTCATGG GGATTCGAGT GCTCCGGTTC 
TCCCTGGTGG TCATCCTTGT GTTGCTGCTG GTAGCGGGGG CTTTGACCAA CTTACTCCCC 
AACATCAAAG AAGACAAGAT GCTCACTCTG CGTAGGGAGA TCAAATCCCC GAGCAAGTCG 
GCCCTGGATT CATTCACCCT CATCATGCAG ACATACAACA GAACAGACCT CTTACTAAGA 
CTCTTAAATC ATTACCAGGC AGTACCGAGT CTGCACAAGG TGATCGTGGT GTGGAACAAT 
GTGGGAGAGA AGGGCCCAGA GGAGTTGTGG AATTCTCTAG GGCCTCACCC GATCCCTGTC 
ATCTTCAAAC CACAAACAGC AAACAAAATG AGAAACCGAC TCCAGGTCTT CCCTGAAGTG 
GAGACCAACG CGGTGTTGAT GGTAGACGAT GACACACTCA TTAGTGCCCA GGACCTTGTT 
TTCGCTTTCT CAATTTGGCA GCAATTTCCT GATCAGATCA TAGGATTTGT ACCTAGAAAG 
CACGTCTCTA CTTCCTCCGG GATCTACAGT TACGGAGGCT TTGAGCTGCA GACACCGGGG 
CCCGGGAATG GCGACCAGTA CTCCATGGTG CTCATCGGAG CCTCCTTCTT CAACAGCAAA 
TACCTGGAAC TCTTCCAGAA GCAGCCTGCA GCCGTCCACG CGCTGATCGA TGAGACGCAG 
AACTGTGACG ACATCGCTAT GAATTTCCTC GTCACCAGGC ACACTGGCAA GCCTTCAGGG 
ATATTCGTGA AACCCATAAA CATGGTCAAC TTGGAAAAAG AAACCAACGG GTATTCCGGA 
ATGTGGCACC GGGCGGAGCA CTTTCTGCAG AGATCCTACT GTATAAATAA GCTCGTTAAC 
ATCTACGACG GCATGCCCTT AAAGTACTCC AACATTATGA TTTCCCAGTT TGGTTTTCCG 
TATGCCAACC ATAAAAGTAA AATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017175163.1
CDS	494..1480
Translation	MGCHICKLPGRVMGIRVLRFSLVVILVLLLVAGALTNLLPNIKEDKMLTLRREIKSPSKSALDSFTLIMQTYNRTDLLLRLLNHYQAVPSLHKVIVVWNNVGEKGPEELWNSLGPHPIPVIFKPQTANKMRNRLQVFPEVETNAVLMVDDDTLISAQDLVFAFSIWQQFPDQIIGFVPRKHVSTSSGIYSYGGFELQTPGPGNGDQYSMVLIGASFFNSKYLELFQKQPAAVHALIDETQNCDDIAMNFLVTRHTGKPSGIFVKPINMVNLEKETNGYSGMWHRAEHFLQRSYCINKLVNIYDGMPLKYSNIMISQFGFPYANHKSKM

Target ORF information:

RefSeq Version	XM_017319674.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus exostoses (multiple)-like 2 (Extl2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017319674.1

ORF Insert Sequence:

ATGGGTTGCC ACATCTGCAA ACTTCCGGGA AGAGTCATGG GGATTCGAGT GCTCCGGTTC 
TCCCTGGTGG TCATCCTTGT GTTGCTGCTG GTAGCGGGGG CTTTGACCAA CTTACTCCCC 
AACATCAAAG AAGACAAGAT GCTCACTCTG CGTAGGGAGA TCAAATCCCC GAGCAAGTCG 
GCCCTGGATT CATTCACCCT CATCATGCAG ACATACAACA GAACAGACCT CTTACTAAGA 
CTCTTAAATC ATTACCAGGC AGTACCGAGT CTGCACAAGG TGATCGTGGT GTGGAACAAT 
GTGGGAGAGA AGGGCCCAGA GGAGTTGTGG AATTCTCTAG GGCCTCACCC GATCCCTGTC 
ATCTTCAAAC CACAAACAGC AAACAAAATG AGAAACCGAC TCCAGGTCTT CCCTGAAGTG 
GAGACCAACG CGGTGTTGAT GGTAGACGAT GACACACTCA TTAGTGCCCA GGACCTTGTT 
TTCGCTTTCT CAATTTGGCA GCAATTTCCT GATCAGATCA TAGGATTTGT ACCTAGAAAG 
CACGTCTCTA CTTCCTCCGG GATCTACAGT TACGGAGGCT TTGAGCTGCA GACACCGGGG 
CCCGGGAATG GCGACCAGTA CTCCATGGTG CTCATCGGAG CCTCCTTCTT CAACAGCAAA 
TACCTGGAAC TCTTCCAGAA GCAGCCTGCA GCCGTCCACG CGCTGATCGA TGAGACGCAG 
AACTGTGACG ACATCGCTAT GAATTTCCTC GTCACCAGGC ACACTGGCAA GCCTTCAGGG 
ATATTCGTGA AACCCATAAA CATGGTCAAC TTGGAAAAAG AAACCAACGG GTATTCCGGA 
ATGTGGCACC GGGCGGAGCA CTTTCTGCAG AGATCCTACT GTATAAATAA GCTCGTTAAC 
ATCTACGACG GCATGCCCTT AAAGTACTCC AACATTATGA TTTCCCAGTT TGGTTTTCCG 
TATGCCAACC ATAAAAGTAA AATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Extl2 ( XM_030252739.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030108599.1 Mus musculus exostoses (multiple)-like 2 (Extl2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu19025
Clone ID Related Accession (Same CDS sequence)	NM_001163515.1 , XM_030252739.1 , XM_006501827.3
Accession Version	XM_030252739.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 951bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	exostosin-like 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000069.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGATTC GAGTGCTCCG GTTCTCCCTG GTGGTCATCC TTGTGTTGCT GCTGGTAGCG 
GGGGCTTTGA CCAACTTACT CCCCAACATC AAAGAAGACA AGATGCTCAC TCTGCGTAGG 
GAGATCAAAT CCCCGAGCAA GTCGGCCCTG GATTCATTCA CCCTCATCAT GCAGACATAC 
AACAGAACAG ACCTCTTACT AAGACTCTTA AATCATTACC AGGCAGTACC GAGTCTGCAC 
AAGGTGATCG TGGTGTGGAA CAATGTGGGA GAGAAGGGCC CAGAGGAGTT GTGGAATTCT 
CTAGGGCCTC ACCCGATCCC TGTCATCTTC AAACCACAAA CAGCAAACAA AATGAGAAAC 
CGACTCCAGG TCTTCCCTGA AGTGGAGACC AACGCGGTGT TGATGGTAGA CGATGACACA 
CTCATTAGTG CCCAGGACCT TGTTTTCGCT TTCTCAATTT GGCAGCAATT TCCTGATCAG 
ATCATAGGAT TTGTACCTAG AAAGCACGTC TCTACTTCCT CCGGGATCTA CAGTTACGGA 
GGCTTTGAGC TGCAGACACC GGGGCCCGGG AATGGCGACC AGTACTCCAT GGTGCTCATC 
GGAGCCTCCT TCTTCAACAG CAAATACCTG GAACTCTTCC AGAAGCAGCC TGCAGCCGTC 
CACGCGCTGA TCGATGAGAC GCAGAACTGT GACGACATCG CTATGAATTT CCTCGTCACC 
AGGCACACTG GCAAGCCTTC AGGGATATTC GTGAAACCCA TAAACATGGT CAACTTGGAA 
AAAGAAACCA ACGGGTATTC CGGAATGTGG CACCGGGCGG AGCACTTTCT GCAGAGATCC 
TACTGTATAA ATAAGCTCGT TAACATCTAC GACGGCATGC CCTTAAAGTA CTCCAACATT 
ATGATTTCCC AGTTTGGTTT TCCGTATGCC AACCATAAAA GTAAAATGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030108599.1
CDS	732..1682
Translation	MGIRVLRFSLVVILVLLLVAGALTNLLPNIKEDKMLTLRREIKSPSKSALDSFTLIMQTYNRTDLLLRLLNHYQAVPSLHKVIVVWNNVGEKGPEELWNSLGPHPIPVIFKPQTANKMRNRLQVFPEVETNAVLMVDDDTLISAQDLVFAFSIWQQFPDQIIGFVPRKHVSTSSGIYSYGGFELQTPGPGNGDQYSMVLIGASFFNSKYLELFQKQPAAVHALIDETQNCDDIAMNFLVTRHTGKPSGIFVKPINMVNLEKETNGYSGMWHRAEHFLQRSYCINKLVNIYDGMPLKYSNIMISQFGFPYANHKSKM

Target ORF information:

RefSeq Version	XM_030252739.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus exostoses (multiple)-like 2 (Extl2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030252739.1

ORF Insert Sequence:

ATGGGGATTC GAGTGCTCCG GTTCTCCCTG GTGGTCATCC TTGTGTTGCT GCTGGTAGCG 
GGGGCTTTGA CCAACTTACT CCCCAACATC AAAGAAGACA AGATGCTCAC TCTGCGTAGG 
GAGATCAAAT CCCCGAGCAA GTCGGCCCTG GATTCATTCA CCCTCATCAT GCAGACATAC 
AACAGAACAG ACCTCTTACT AAGACTCTTA AATCATTACC AGGCAGTACC GAGTCTGCAC 
AAGGTGATCG TGGTGTGGAA CAATGTGGGA GAGAAGGGCC CAGAGGAGTT GTGGAATTCT 
CTAGGGCCTC ACCCGATCCC TGTCATCTTC AAACCACAAA CAGCAAACAA AATGAGAAAC 
CGACTCCAGG TCTTCCCTGA AGTGGAGACC AACGCGGTGT TGATGGTAGA CGATGACACA 
CTCATTAGTG CCCAGGACCT TGTTTTCGCT TTCTCAATTT GGCAGCAATT TCCTGATCAG 
ATCATAGGAT TTGTACCTAG AAAGCACGTC TCTACTTCCT CCGGGATCTA CAGTTACGGA 
GGCTTTGAGC TGCAGACACC GGGGCCCGGG AATGGCGACC AGTACTCCAT GGTGCTCATC 
GGAGCCTCCT TCTTCAACAG CAAATACCTG GAACTCTTCC AGAAGCAGCC TGCAGCCGTC 
CACGCGCTGA TCGATGAGAC GCAGAACTGT GACGACATCG CTATGAATTT CCTCGTCACC 
AGGCACACTG GCAAGCCTTC AGGGATATTC GTGAAACCCA TAAACATGGT CAACTTGGAA 
AAAGAAACCA ACGGGTATTC CGGAATGTGG CACCGGGCGG AGCACTTTCT GCAGAGATCC 
TACTGTATAA ATAAGCTCGT TAACATCTAC GACGGCATGC CCTTAAAGTA CTCCAACATT 
ATGATTTCCC AGTTTGGTTT TCCGTATGCC AACCATAAAA GTAAAATGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Extl2 ( XM_011240177.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011238479.1 Mus musculus exostoses (multiple)-like 2 (Extl2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu69770
Clone ID Related Accession (Same CDS sequence)	XM_011240177.3 , XM_011240177.2 , XM_017319674.1
Accession Version	XM_011240177.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 987bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	exostosin-like 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000069.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011240177.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTTGCC ACATCTGCAA ACTTCCGGGA AGAGTCATGG GGATTCGAGT GCTCCGGTTC 
TCCCTGGTGG TCATCCTTGT GTTGCTGCTG GTAGCGGGGG CTTTGACCAA CTTACTCCCC 
AACATCAAAG AAGACAAGAT GCTCACTCTG CGTAGGGAGA TCAAATCCCC GAGCAAGTCG 
GCCCTGGATT CATTCACCCT CATCATGCAG ACATACAACA GAACAGACCT CTTACTAAGA 
CTCTTAAATC ATTACCAGGC AGTACCGAGT CTGCACAAGG TGATCGTGGT GTGGAACAAT 
GTGGGAGAGA AGGGCCCAGA GGAGTTGTGG AATTCTCTAG GGCCTCACCC GATCCCTGTC 
ATCTTCAAAC CACAAACAGC AAACAAAATG AGAAACCGAC TCCAGGTCTT CCCTGAAGTG 
GAGACCAACG CGGTGTTGAT GGTAGACGAT GACACACTCA TTAGTGCCCA GGACCTTGTT 
TTCGCTTTCT CAATTTGGCA GCAATTTCCT GATCAGATCA TAGGATTTGT ACCTAGAAAG 
CACGTCTCTA CTTCCTCCGG GATCTACAGT TACGGAGGCT TTGAGCTGCA GACACCGGGG 
CCCGGGAATG GCGACCAGTA CTCCATGGTG CTCATCGGAG CCTCCTTCTT CAACAGCAAA 
TACCTGGAAC TCTTCCAGAA GCAGCCTGCA GCCGTCCACG CGCTGATCGA TGAGACGCAG 
AACTGTGACG ACATCGCTAT GAATTTCCTC GTCACCAGGC ACACTGGCAA GCCTTCAGGG 
ATATTCGTGA AACCCATAAA CATGGTCAAC TTGGAAAAAG AAACCAACGG GTATTCCGGA 
ATGTGGCACC GGGCGGAGCA CTTTCTGCAG AGATCCTACT GTATAAATAA GCTCGTTAAC 
ATCTACGACG GCATGCCCTT AAAGTACTCC AACATTATGA TTTCCCAGTT TGGTTTTCCG 
TATGCCAACC ATAAAAGTAA AATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011238479.1
CDS	596..1582
Translation	MGCHICKLPGRVMGIRVLRFSLVVILVLLLVAGALTNLLPNIKEDKMLTLRREIKSPSKSALDSFTLIMQTYNRTDLLLRLLNHYQAVPSLHKVIVVWNNVGEKGPEELWNSLGPHPIPVIFKPQTANKMRNRLQVFPEVETNAVLMVDDDTLISAQDLVFAFSIWQQFPDQIIGFVPRKHVSTSSGIYSYGGFELQTPGPGNGDQYSMVLIGASFFNSKYLELFQKQPAAVHALIDETQNCDDIAMNFLVTRHTGKPSGIFVKPINMVNLEKETNGYSGMWHRAEHFLQRSYCINKLVNIYDGMPLKYSNIMISQFGFPYANHKSKM

Target ORF information:

RefSeq Version	XM_011240177.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus exostoses (multiple)-like 2 (Extl2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011240177.3

ORF Insert Sequence:

ATGGGTTGCC ACATCTGCAA ACTTCCGGGA AGAGTCATGG GGATTCGAGT GCTCCGGTTC 
TCCCTGGTGG TCATCCTTGT GTTGCTGCTG GTAGCGGGGG CTTTGACCAA CTTACTCCCC 
AACATCAAAG AAGACAAGAT GCTCACTCTG CGTAGGGAGA TCAAATCCCC GAGCAAGTCG 
GCCCTGGATT CATTCACCCT CATCATGCAG ACATACAACA GAACAGACCT CTTACTAAGA 
CTCTTAAATC ATTACCAGGC AGTACCGAGT CTGCACAAGG TGATCGTGGT GTGGAACAAT 
GTGGGAGAGA AGGGCCCAGA GGAGTTGTGG AATTCTCTAG GGCCTCACCC GATCCCTGTC 
ATCTTCAAAC CACAAACAGC AAACAAAATG AGAAACCGAC TCCAGGTCTT CCCTGAAGTG 
GAGACCAACG CGGTGTTGAT GGTAGACGAT GACACACTCA TTAGTGCCCA GGACCTTGTT 
TTCGCTTTCT CAATTTGGCA GCAATTTCCT GATCAGATCA TAGGATTTGT ACCTAGAAAG 
CACGTCTCTA CTTCCTCCGG GATCTACAGT TACGGAGGCT TTGAGCTGCA GACACCGGGG 
CCCGGGAATG GCGACCAGTA CTCCATGGTG CTCATCGGAG CCTCCTTCTT CAACAGCAAA 
TACCTGGAAC TCTTCCAGAA GCAGCCTGCA GCCGTCCACG CGCTGATCGA TGAGACGCAG 
AACTGTGACG ACATCGCTAT GAATTTCCTC GTCACCAGGC ACACTGGCAA GCCTTCAGGG 
ATATTCGTGA AACCCATAAA CATGGTCAAC TTGGAAAAAG AAACCAACGG GTATTCCGGA 
ATGTGGCACC GGGCGGAGCA CTTTCTGCAG AGATCCTACT GTATAAATAA GCTCGTTAAC 
ATCTACGACG GCATGCCCTT AAAGTACTCC AACATTATGA TTTCCCAGTT TGGTTTTCCG 
TATGCCAACC ATAAAAGTAA AATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Exostosin-like 2 regulates FGF2 signaling by controlling the endocytosis of FGF2.
Biochimica et biophysica acta1862(4)791-799(2018 Jan)
Nadanaka S,Kitagawa H

EXTL2 controls liver regeneration and aortic calcification through xylose kinase-dependent regulation of glycosaminoglycan biosynthesis.
Matrix biology : journal of the International Society for Matrix Biology3518-24(2014 Apr)
Nadanaka S,Kitagawa H

Roles of EXTL2, a member of the EXT family of tumour suppressors, in liver injury and regeneration processes.
The Biochemical journal454(1)133-45(2013 Aug)
Nadanaka S,Kagiyama S,Kitagawa H

EXTL2, a member of the EXT family of tumor suppressors, controls glycosaminoglycan biosynthesis in a xylose kinase-dependent manner.
The Journal of biological chemistry288(13)9321-33(2013 Mar)
Nadanaka S,Zhou S,Kagiyama S,Shoji N,Sugahara K,Sugihara K,Asano M,Kitagawa H

Crystal structure of an alpha 1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis.
The Journal of biological chemistry278(16)14420-8(2003 Apr)
Pedersen LC,Dong J,Taniguchi F,Kitagawa H,Krahn JM,Pedersen LG,Sugahara K,Negishi M

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Extl2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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