Defb46 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Defb46
Entrez Gene ID	574081
Full Name	defensin beta 46
Synonyms	Defb53,EG574081
General protein information	Preferred Names defensin beta 46 Names beta-defensin 53 beta-defensin 50
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8 A1.3\|8

mRNA and Protein(s)

mRNA	Protein	Name
NM_001025351.1	NP_001020522.1	beta-defensin 53 precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Manual annotation and analysis of the defensin gene cluster in the C57BL/6J mouse reference genome.
Amid C, Rehaume LM, Brown KL, Gilbert JG, Dougan G, Hancock RE, Harrow JL
BMC genomics10606(2009 Dec)

Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract.
Patil AA, Cai Y, Sang Y, Blecha F, Zhang G
Physiological genomics23(1)5-17(2005 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Defb46 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Defb46 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu25299	NM_001025351.1 Latest version!	Mus musculus defensin beta 46 (Defb46), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Defb46 ( NM_001025351.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001020522.1 Mus musculus defensin beta 46 (Defb46), mRNA.

Price & Availability↑

CloneID	OMu25299
Clone ID Related Accession (Same CDS sequence)	NM_001025351.1
Accession Version	NM_001025351.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 174bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Mus musculus(house mouse)
Product	beta-defensin 53 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY621335.1. ##Evidence-Data-START## Transcript exon combination :: AY621335.1, DQ012053.1 [ECO:0000332] ##Evidence-Data-END##

1
61
121

ATGAGGATCC ATTACCTTCT CTTTGCATTT CTCCTGGTGC TGCTCTCTCC ATGTGCAGCT 
TGTATCCAAA TAATTAGTTC AATAAGAGGT GTCTGCTGGG GTCAGTGTGT TTCTGGCACT 
AGAGAGATTG GCATGTCTGG CCTTCGTAGT ATGAAATGCT GCATAAGAAA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020522.1
CDS	1..174
Translation	MRIHYLLFAFLLVLLSPCAACIQIISSIRGVCWGQCVSGTREIGMSGLRSMKCCIRK

Target ORF information:

RefSeq Version	NM_001025351.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus defensin beta 46 (Defb46), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025351.1

ORF Insert Sequence:

1
61
121

ATGAGGATCC ATTACCTTCT CTTTGCATTT CTCCTGGTGC TGCTCTCTCC ATGTGCAGCT 
TGTATCCAAA TAATTAGTTC AATAAGAGGT GTCTGCTGGG GTCAGTGTGT TTCTGGCACT 
AGAGAGATTG GCATGTCTGG CCTTCGTAGT ATGAAATGCT GCATAAGAAA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Manual annotation and analysis of the defensin gene cluster in the C57BL/6J mouse reference genome.
BMC genomics10606(2009 Dec)
Amid C,Rehaume LM,Brown KL,Gilbert JG,Dougan G,Hancock RE,Harrow JL

Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract.
Physiological genomics23(1)5-17(2005 Sep)
Patil AA,Cai Y,Sang Y,Blecha F,Zhang G