Retnlb cDNA ORF clone, Mus musculus(house mouse)

Resistin-like molecule ? is a bactericidal protein that promotes spatial segregation of the microbiota and the colonic epithelium.
Propheter DC, Chara AL, Harris TA, Ruhn KA, Hooper LV
Proceedings of the National Academy of Sciences of the United States of America114(42)11027-11033(2017 Oct)

Pathological Type-2 Immune Response, Enhanced Tumor Growth, and Glucose Intolerance in Retnl? (RELM?) Null Mice: A Model of Intestinal Immune System Dysfunction in Disease Susceptibility.
Wernstedt Asterholm I, Kim-Muller JY, Rutkowski JM, Crewe C, Tao C, Scherer PE
The American journal of pathology186(9)2404-16(2016 Sep)

Opposing roles of nuclear receptor HNF4? isoforms in colitis and colitis-associated colon cancer.
Chellappa K, Deol P, Evans JR, Vuong LM, Chen G, Brian?on N, Bolotin E, Lytle C, Nair MG, Sladek FM
eLife5(2016 05)

Comparison of RELM? and RELM? Single- and Double-Gene-Deficient Mice Reveals that RELM? Expression Dictates Inflammation and Worm Expulsion in Hookworm Infection.
Chen G, Wang SH, Jang JC, Odegaard JI, Nair MG
Infection and immunity84(4)1100-11(2016 Apr)

Involvement of resistin-like molecule ? in the development of methionine-choline deficient diet-induced non-alcoholic steatohepatitis in mice.
Okubo H, Kushiyama A, Sakoda H, Nakatsu Y, Iizuka M, Taki N, Fujishiro M, Fukushima T, Kamata H, Nagamachi A, Inaba T, Nishimura F, Katagiri H, Asahara T, Yoshida Y, Chonan O, Encinas J, Asano T
Scientific reports620157(2016 Jan)

The goblet cell-derived RELM-beta drives spontaneous colitis in Muc2-deficient mice by promoting commensal microbial dysbiosis.
Title: The goblet cell-derived mediator RELM-? drives spontaneous colitis in Muc2-deficient mice by promoting commensal microbial dysbiosis.

lack of RELMbeta leads to increased colonic expression of T helper cell type-2 cytokines and IL-17, associated with a reduced ability to maintain intestinal homeostasis
Title: Pathological Type-2 Immune Response, Enhanced Tumor Growth, and Glucose Intolerance in Retnl? (RELM?) Null Mice: A Model of Intestinal Immune System Dysfunction in Disease Susceptibility.

These data demonstrate that RELMalpha but not RELMbeta significantly impacts the immune response to N. brasiliensis infection by downregulating the Th2 adaptive immune response in the lung.
Title: Comparison of RELM? and RELM? Single- and Double-Gene-Deficient Mice Reveals that RELM? Expression Dictates Inflammation and Worm Expulsion in Hookworm Infection.

These data suggest the contribution of increases in RELMbeta in the gut and Kupffer cells to NASH development, raising the possibility of RELMbeta being a novel therapeutic target for NASH.
Title: Involvement of resistin-like molecule ? in the development of methionine-choline deficient diet-induced non-alcoholic steatohepatitis in mice.

findings demonstrate that RELM-beta and goblet cells play an unexpected, yet critical role in recruiting CD4+ T cells to the colon to protect against an enteric pathogen
Title: Goblet Cell Derived RELM-? Recruits CD4+ T Cells during Infectious Colitis to Promote Protective Intestinal Epithelial Cell Proliferation.