Abcb10 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Abcb10
Entrez Gene ID	56199
Full Name	ATP-binding cassette, sub-family B (MDR/TAP), member 10
Synonyms	Abc-me,Abcb12
General protein information	Preferred Names ATP-binding cassette, sub-family B (MDR/TAP), member 10 Names ATP-binding cassette sub-family B member 10, mitochondrial ABC-mitochondrial erythroid protein ATP-binding cassette transporter 10
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8\|8 E2
Summary	This gene encodes a member of the ATP-binding cassette superfamily of transporters. ATP-binding cassette proteins transport various molecules across extra- and intra-cellular membranes. The encoded protein is localized to the mitochondrial inner membrane where it interacts with and stabilizes mitoferrin-1, and is important for heme biosynthesis. Additional evidence suggests the encoded protein is involved in oxidative stress protection and erythropoisesis. [provided by RefSeq, May 2013].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006531201.3	XP_006531264.1	ATP-binding cassette sub-family B member 10, mitochondrial isoform X1
NM_019552.2	NP_062425.1	ATP-binding cassette sub-family B member 10, mitochondrial precursor
XM_006531201.4	XP_006531264.1	ATP-binding cassette sub-family B member 10, mitochondrial isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	ABCB10	NP_036221.2
Bos taurus (cattle)	ABCB10	XP_002698814.2
Rattus norvegicus (Norway rat)	Abcb10	NP_001012166.1
Caenorhabditis elegans (roundworm)	haf-3	NP_506927.2
Eremothecium gossypii	AGOS_ACR022W	NP_983425.2
Neurospora crassa	NCU04117	XP_961273.2
Canis lupus familiaris (dog)	ABCB10	XP_005618913.1
Kluyveromyces lactis	KLLA0D00748g	XP_453105.1
Schizosaccharomyces pombe (fission yeast)	mdl1	NP_595751.1
Arabidopsis thaliana (thale cress)	TAP2	NP_198720.2
Mus musculus (house mouse)	Abcb10	NP_062425.1
Gallus gallus (chicken)	ABCB10	XP_419578.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002717	XP_312209.4
Caenorhabditis elegans (roundworm)	haf-1	NP_503098.2
Saccharomyces cerevisiae (baker's yeast)	MDL2	NP_015053.2
Pan troglodytes (chimpanzee)	ABCB10	XP_003308870.1
	ABCB10	XP_001082734.1
Danio rerio (zebrafish)	abcb10	XP_001343218.3
Drosophila melanogaster (fruit fly)	CG3156	NP_569844.2
Magnaporthe oryzae (rice blast fungus)	MGG_06878	XP_003709605.1
Oryza sativa (rice)	Os03g0755100	NP_001051311.1

Gene Ontology
Bibliography

Related articles in PubMed

Blood-brain barrier disruption in diabetic mice is linked to Nrf2 signaling deficits: Role of ABCB10?
Sajja RK, Prasad S, Tang S, Kaisar MA, Cucullo L
Neuroscience letters653152-158(2017 Jul)

Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs.
Pan J, Mor G, Ju W, Zhong J, Luo X, Aldo PB, Zhong M, Yu Y, Jenkins EC, Brown WT, Zhong N
American journal of reproductive immunology (New York, N.Y. : 1989)74(3)237-57(2015 Sep)

ATP Binding and Hydrolysis Properties of ABCB10 and Their Regulation by Glutathione.
Qiu W, Liesa M, Carpenter EP, Shirihai OS
PloS one10(6)e0129772(2015)

Abcb10 role in heme biosynthesis in vivo: Abcb10 knockout in mice causes anemia with protoporphyrin IX and iron accumulation.
Yamamoto M, Arimura H, Fukushige T, Minami K, Nishizawa Y, Tanimoto A, Kanekura T, Nakagawa M, Akiyama S, Furukawa T
Molecular and cellular biology34(6)1077-84(2014 Mar)

Snx3 regulates recycling of the transferrin receptor and iron assimilation.
Chen C, Garcia-Santos D, Ishikawa Y, Seguin A, Li L, Fegan KH, Hildick-Smith GJ, Shah DI, Cooney JD, Chen W, King MJ, Yien YY, Schultz IJ, Anderson H, Dalton AJ, Freedman ML, Kingsley PD, Palis J, Hattangadi SM, Lodish HF, Ward DM, Kaplan J, Maeda T, Ponka P, Paw BH
Cell metabolism17(3)343-52(2013 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ATP binding and hydrolysis properties of ABCB10 by using the 8-azido-ATP photolabeling technique, was characterized.
Title: ATP Binding and Hydrolysis Properties of ABCB10 and Their Regulation by Glutathione.

A critical role for Abcb10 in heme biosynthesis.
Title: Abcb10 role in heme biosynthesis in vivo: Abcb10 knockout in mice causes anemia with protoporphyrin IX and iron accumulation.

ABC-me deletion causes an increase in mitochondrial superoxide production and protein carbonylation in erythroid precursors.
Title: The mitochondrial transporter ABC-me (ABCB10), a downstream target of GATA-1, is essential for erythropoiesis in vivo.

Ferrochelatase forms an oligomeric complex with Mfrn1 and Abcb10 to synergistically integrate mitochondrial iron importation and use for heme biosynthesis.
Title: Ferrochelatase forms an oligomeric complex with mitoferrin-1 and Abcb10 for erythroid heme biosynthesis.

Data show that the binding domain of Mfrn1-Abcb10 interaction maps to the N terminus of Mfrn1.
Title: Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria.

The following Abcb10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Abcb10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu41620	XM_006531201.4 Latest version!	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 10 (Abcb10), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu18731	NM_019552.2 Latest version!	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 10 (Abcb10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
View Old Accession Versions >>
OMu41620	XM_006531201.3	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 10 (Abcb10), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Abcb10 ( XM_006531201.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006531264.1 Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 10 (Abcb10), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu41620
Clone ID Related Accession (Same CDS sequence)	XM_006531201.3 , XM_006531201.4
Accession Version	XM_006531201.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1143bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	ATP-binding cassette sub-family B member 10, mitochondrial isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000074.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006531201.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACGGAAG TGGAGAAGTA CACCGGCCGA GTGGACCAGT TGCTGCAGCT GGCACAGAAG 
GAGGCCTTGG CACGAGCCGG CTTCTTTGGA GCAGCTGGGC TCTCAGGAAA CCTGATTGTG 
CTGTCTGTCC TGTACAAAGG AGGCCTGCTG ATGGGCAGTG CCCATATGAC AGTGGGCGAG 
CTCTCTTCCT TCCTCATGTA CGCTTTCTGG GTTGGATTGA GCATCGGAGG ACTGAGTTCA 
TTCTACTCCG AGCTGATGAA AGGCCTGGGT GCTGGTGGGC GGCTCTGGGA GCTGCTGGAG 
AGACAGCCAC GGCTGCCTTT TAACGAGGGG ATGGTGTTAG ATGAGAAAAC CTTCCAGGGT 
GCCCTGGAGT TCAGAAACGT GCACTTCACA TACCCTGCTC GCCCAGAGGT GTCCGTATTC 
CAGGATTTCA GTCTTTCCAT CCCATCTGGA TCTGTCACAG CGCTGGTTGG CCCAAGTGGT 
TCTGGGAAAT CAACAGTGGT TTCGCTCCTG CTGCGGTTGT ACGACCCTAA TTCTGGAACA 
GTCAGCCTTG ATGGCCATGA CATTCGTCAG CTAAACCCCG TCTGGCTGAG ATCCAAGATT 
GGGACAGTGA GTCAGGAGCC AGTCCTGTTC TCCTGCTCTG TCGCTGAGAA CATTGCCTAT 
GGAGCTGACA ACCTCTCCTC GGTCACAGCC CAGCAGGTGG AGAGGGCCGC AGAGGTGGCC 
AACGCCGCTG AGTTCATCCG AAGCTTCCCA CAGGGCTTCG ACACTGTGGT CGGGGAGAAG 
GGCATCCTCC TGTCAGGTGG GCAGAAGCAG AGGATTGCAA TAGCCAGAGC CCTGCTGAAG 
AACCCCAAAA TTCTTCTCCT TGATGAAGCA ACCAGTGCAC TGGATGCCGA AAATGAGCAC 
CTGGTCCAGG AGGCCCTTGA CCGGCTGATG GAAGGGAGAA CCGTGCTGAT CATAGCCCAC 
CGCCTGTCCA CCATTAAGAA TGCCAACTTT GTTGCTGTCC TTGACCACGG AAAGATCTGT 
GAACACGGGA CACATGAAGA GCTGCTCCTG AAGCCCAATG GGCTTTACAG AAAACTGATG 
AACAAGCAGA GTTTCCTGTC ATATAATGGA GCAGAGCAGT TCCTGGAACC TGCACGGGCG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006531264.1
CDS	367..1509
Translation	MTEVEKYTGRVDQLLQLAQKEALARAGFFGAAGLSGNLIVLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVGLSIGGLSSFYSELMKGLGAGGRLWELLERQPRLPFNEGMVLDEKTFQGALEFRNVHFTYPARPEVSVFQDFSLSIPSGSVTALVGPSGSGKSTVVSLLLRLYDPNSGTVSLDGHDIRQLNPVWLRSKIGTVSQEPVLFSCSVAENIAYGADNLSSVTAQQVERAAEVANAAEFIRSFPQGFDTVVGEKGILLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEHLVQEALDRLMEGRTVLIIAHRLSTIKNANFVAVLDHGKICEHGTHEELLLKPNGLYRKLMNKQSFLSYNGAEQFLEPARA

Target ORF information:

RefSeq Version	XM_006531201.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 10 (Abcb10), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006531201.3

ORF Insert Sequence:

ATGACGGAAG TGGAGAAGTA CACCGGCCGA GTGGACCAGT TGCTGCAGCT GGCACAGAAG 
GAGGCCTTGG CACGAGCCGG CTTCTTTGGA GCAGCTGGGC TCTCAGGAAA CCTGATTGTG 
CTGTCTGTCC TGTACAAAGG AGGCCTGCTG ATGGGCAGTG CCCATATGAC AGTGGGCGAG 
CTCTCTTCCT TCCTCATGTA CGCTTTCTGG GTTGGATTGA GCATCGGAGG ACTGAGTTCA 
TTCTACTCCG AGCTGATGAA AGGCCTGGGT GCTGGTGGGC GGCTCTGGGA GCTGCTGGAG 
AGACAGCCAC GGCTGCCTTT TAACGAGGGG ATGGTGTTAG ATGAGAAAAC CTTCCAGGGT 
GCCCTGGAGT TCAGAAACGT GCACTTCACA TACCCTGCTC GCCCAGAGGT GTCCGTATTC 
CAGGATTTCA GTCTTTCCAT CCCATCTGGA TCTGTCACAG CGCTGGTTGG CCCAAGTGGT 
TCTGGGAAAT CAACAGTGGT TTCGCTCCTG CTGCGGTTGT ACGACCCTAA TTCTGGAACA 
GTCAGCCTTG ATGGCCATGA CATTCGTCAG CTAAACCCCG TCTGGCTGAG ATCCAAGATT 
GGGACAGTGA GTCAGGAGCC AGTCCTGTTC TCCTGCTCTG TCGCTGAGAA CATTGCCTAT 
GGAGCTGACA ACCTCTCCTC GGTCACAGCC CAGCAGGTGG AGAGGGCCGC AGAGGTGGCC 
AACGCCGCTG AGTTCATCCG AAGCTTCCCA CAGGGCTTCG ACACTGTGGT CGGGGAGAAG 
GGCATCCTCC TGTCAGGTGG GCAGAAGCAG AGGATTGCAA TAGCCAGAGC CCTGCTGAAG 
AACCCCAAAA TTCTTCTCCT TGATGAAGCA ACCAGTGCAC TGGATGCCGA AAATGAGCAC 
CTGGTCCAGG AGGCCCTTGA CCGGCTGATG GAAGGGAGAA CCGTGCTGAT CATAGCCCAC 
CGCCTGTCCA CCATTAAGAA TGCCAACTTT GTTGCTGTCC TTGACCACGG AAAGATCTGT 
GAACACGGGA CACATGAAGA GCTGCTCCTG AAGCCCAATG GGCTTTACAG AAAACTGATG 
AACAAGCAGA GTTTCCTGTC ATATAATGGA GCAGAGCAGT TCCTGGAACC TGCACGGGCG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abcb10 ( XM_006531201.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006531264.1 Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 10 (Abcb10), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu41620
Clone ID Related Accession (Same CDS sequence)	XM_006531201.3 , XM_006531201.4
Accession Version	XM_006531201.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1143bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	ATP-binding cassette sub-family B member 10, mitochondrial isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000074.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006531201.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACGGAAG TGGAGAAGTA CACCGGCCGA GTGGACCAGT TGCTGCAGCT GGCACAGAAG 
GAGGCCTTGG CACGAGCCGG CTTCTTTGGA GCAGCTGGGC TCTCAGGAAA CCTGATTGTG 
CTGTCTGTCC TGTACAAAGG AGGCCTGCTG ATGGGCAGTG CCCATATGAC AGTGGGCGAG 
CTCTCTTCCT TCCTCATGTA CGCTTTCTGG GTTGGATTGA GCATCGGAGG ACTGAGTTCA 
TTCTACTCCG AGCTGATGAA AGGCCTGGGT GCTGGTGGGC GGCTCTGGGA GCTGCTGGAG 
AGACAGCCAC GGCTGCCTTT TAACGAGGGG ATGGTGTTAG ATGAGAAAAC CTTCCAGGGT 
GCCCTGGAGT TCAGAAACGT GCACTTCACA TACCCTGCTC GCCCAGAGGT GTCCGTATTC 
CAGGATTTCA GTCTTTCCAT CCCATCTGGA TCTGTCACAG CGCTGGTTGG CCCAAGTGGT 
TCTGGGAAAT CAACAGTGGT TTCGCTCCTG CTGCGGTTGT ACGACCCTAA TTCTGGAACA 
GTCAGCCTTG ATGGCCATGA CATTCGTCAG CTAAACCCCG TCTGGCTGAG ATCCAAGATT 
GGGACAGTGA GTCAGGAGCC AGTCCTGTTC TCCTGCTCTG TCGCTGAGAA CATTGCCTAT 
GGAGCTGACA ACCTCTCCTC GGTCACAGCC CAGCAGGTGG AGAGGGCCGC AGAGGTGGCC 
AACGCCGCTG AGTTCATCCG AAGCTTCCCA CAGGGCTTCG ACACTGTGGT CGGGGAGAAG 
GGCATCCTCC TGTCAGGTGG GCAGAAGCAG AGGATTGCAA TAGCCAGAGC CCTGCTGAAG 
AACCCCAAAA TTCTTCTCCT TGATGAAGCA ACCAGTGCAC TGGATGCCGA AAATGAGCAC 
CTGGTCCAGG AGGCCCTTGA CCGGCTGATG GAAGGGAGAA CCGTGCTGAT CATAGCCCAC 
CGCCTGTCCA CCATTAAGAA TGCCAACTTT GTTGCTGTCC TTGACCACGG AAAGATCTGT 
GAACACGGGA CACATGAAGA GCTGCTCCTG AAGCCCAATG GGCTTTACAG AAAACTGATG 
AACAAGCAGA GTTTCCTGTC ATATAATGGA GCAGAGCAGT TCCTGGAACC TGCACGGGCG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006531264.1
CDS	371..1513
Translation	MTEVEKYTGRVDQLLQLAQKEALARAGFFGAAGLSGNLIVLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVGLSIGGLSSFYSELMKGLGAGGRLWELLERQPRLPFNEGMVLDEKTFQGALEFRNVHFTYPARPEVSVFQDFSLSIPSGSVTALVGPSGSGKSTVVSLLLRLYDPNSGTVSLDGHDIRQLNPVWLRSKIGTVSQEPVLFSCSVAENIAYGADNLSSVTAQQVERAAEVANAAEFIRSFPQGFDTVVGEKGILLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEHLVQEALDRLMEGRTVLIIAHRLSTIKNANFVAVLDHGKICEHGTHEELLLKPNGLYRKLMNKQSFLSYNGAEQFLEPARA

Target ORF information:

RefSeq Version	XM_006531201.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 10 (Abcb10), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006531201.4

ORF Insert Sequence:

ATGACGGAAG TGGAGAAGTA CACCGGCCGA GTGGACCAGT TGCTGCAGCT GGCACAGAAG 
GAGGCCTTGG CACGAGCCGG CTTCTTTGGA GCAGCTGGGC TCTCAGGAAA CCTGATTGTG 
CTGTCTGTCC TGTACAAAGG AGGCCTGCTG ATGGGCAGTG CCCATATGAC AGTGGGCGAG 
CTCTCTTCCT TCCTCATGTA CGCTTTCTGG GTTGGATTGA GCATCGGAGG ACTGAGTTCA 
TTCTACTCCG AGCTGATGAA AGGCCTGGGT GCTGGTGGGC GGCTCTGGGA GCTGCTGGAG 
AGACAGCCAC GGCTGCCTTT TAACGAGGGG ATGGTGTTAG ATGAGAAAAC CTTCCAGGGT 
GCCCTGGAGT TCAGAAACGT GCACTTCACA TACCCTGCTC GCCCAGAGGT GTCCGTATTC 
CAGGATTTCA GTCTTTCCAT CCCATCTGGA TCTGTCACAG CGCTGGTTGG CCCAAGTGGT 
TCTGGGAAAT CAACAGTGGT TTCGCTCCTG CTGCGGTTGT ACGACCCTAA TTCTGGAACA 
GTCAGCCTTG ATGGCCATGA CATTCGTCAG CTAAACCCCG TCTGGCTGAG ATCCAAGATT 
GGGACAGTGA GTCAGGAGCC AGTCCTGTTC TCCTGCTCTG TCGCTGAGAA CATTGCCTAT 
GGAGCTGACA ACCTCTCCTC GGTCACAGCC CAGCAGGTGG AGAGGGCCGC AGAGGTGGCC 
AACGCCGCTG AGTTCATCCG AAGCTTCCCA CAGGGCTTCG ACACTGTGGT CGGGGAGAAG 
GGCATCCTCC TGTCAGGTGG GCAGAAGCAG AGGATTGCAA TAGCCAGAGC CCTGCTGAAG 
AACCCCAAAA TTCTTCTCCT TGATGAAGCA ACCAGTGCAC TGGATGCCGA AAATGAGCAC 
CTGGTCCAGG AGGCCCTTGA CCGGCTGATG GAAGGGAGAA CCGTGCTGAT CATAGCCCAC 
CGCCTGTCCA CCATTAAGAA TGCCAACTTT GTTGCTGTCC TTGACCACGG AAAGATCTGT 
GAACACGGGA CACATGAAGA GCTGCTCCTG AAGCCCAATG GGCTTTACAG AAAACTGATG 
AACAAGCAGA GTTTCCTGTC ATATAATGGA GCAGAGCAGT TCCTGGAACC TGCACGGGCG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abcb10 ( NM_019552.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_062425.1 Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 10 (Abcb10), mRNA.

Price & Availability↑

CloneID	OMu18731
Clone ID Related Accession (Same CDS sequence)	NM_019552.2
Accession Version	NM_019552.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2148bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Mus musculus(house mouse)
Product	ATP-binding cassette sub-family B member 10, mitochondrial precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC054793.1. On or before Dec 7, 2005 this sequence version replaced XM_925245.1, XM_917783.1, XM_925251.1, XM_925254.1, NM_019552.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC054793.1, AK081782.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164140, SAMN01164143 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: PMID: 15215243; reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCGCGCCC CTTCTGCTAG GGCGCTACTG CTGATTCCGC GTCGGGGCCC TGCCGTGCGA 
GCGTGGGCCC CGGCCGTCTC CTCTCGGATA TGGCTGGCTT CTGAATGGAC CCCGCTCGTA 
CGCGCGTGGA CCTCTCTGAT CCACAAGCCG GGTTCGGGCC TCCGCTTTCC CGCGCCCCTA 
TCCGGGCTGC CTGGCGGCGT GGGGCAGTGG GCCACCTCCT CGGGGGCCCG CAGGTGCTGG 
GTGCTGGCAG GACCCCGCGC CGCACATCCC CTGTTCGCCA GGCTCCAGGG TGCAGCTGCC 
ACCGGTGTGC GAGACCTTGG GAACGACTCG CAGCGGCGTC CCGCGGCGAC CGGGCGCTCA 
GAAGTATGGA AGCTCCTAGG GCTGGTGCGC CCCGAGCGCG GGAGACTGTC AGCTGCAGTT 
GGGTTTCTGG CTGTGTCCAG TGTCATCACC ATGTCTGCCC CCTTCTTCCT GGGAAGGATC 
ATTGATGTCA TCTATACCAA CCCAAGCGAG GGCTATGGCG ATAGCTTGAC TCGGCTCTGT 
GCTGTGCTCA CCTGTGTGTT CCTGTGCGGC GCTGCTGCCA ACGGCATTCG TGTCTACCTC 
ATGCAGTCTT CAGGTCAGAG CATTGTGAAC AGGCTGCGCA CCTCTCTGTT CTCCTCCATT 
CTAAGGCAAG AGGTTGCTTT CTTTGACAAG ACCCGCACAG GCGAATTAAT TAACCGCCTC 
TCCTCGGATA CCGCACTCCT GGGGCGCTCC GTGACTGAGA ACCTCTCCGA TGGCCTGAGA 
GCTGGGGCCC AGGCCTCCGT TGGTGTTGGC ATGATGTTTT TTGTGTCACC AAGTCTGGCC 
ACCTTTGTTC TGAGTGTGGT ACCGCCCATC TCTGTCCTCG CTGTGATTTA TGGGCGATAT 
CTACGGAAAC TGTCCAAAGC CACACAGGAC TCCTTGGCAG AAGCCACACA GCTAGCCGAG 
GAGCGGATTG GAAACATAAG AACCATCCGA GCTTTTGGGA AGGAGATGAC GGAAGTGGAG 
AAGTACACCG GCCGAGTGGA CCAGTTGCTG CAGCTGGCAC AGAAGGAGGC CTTGGCACGA 
GCCGGCTTCT TTGGAGCAGC TGGGCTCTCA GGAAACCTGA TTGTGCTGTC TGTCCTGTAC 
AAAGGAGGCC TGCTGATGGG CAGTGCCCAT ATGACAGTGG GCGAGCTCTC TTCCTTCCTC 
ATGTACGCTT TCTGGGTTGG ATTGAGCATC GGAGGACTGA GTTCATTCTA CTCCGAGCTG 
ATGAAAGGCC TGGGTGCTGG TGGGCGGCTC TGGGAGCTGC TGGAGAGACA GCCACGGCTG 
CCTTTTAACG AGGGGATGGT GTTAGATGAG AAAACCTTCC AGGGTGCCCT GGAGTTCAGA 
AACGTGCACT TCACATACCC TGCTCGCCCA GAGGTGTCCG TATTCCAGGA TTTCAGTCTT 
TCCATCCCAT CTGGATCTGT CACAGCGCTG GTTGGCCCAA GTGGTTCTGG GAAATCAACA 
GTGGTTTCGC TCCTGCTGCG GTTGTACGAC CCTAATTCTG GAACAGTCAG CCTTGATGGC 
CATGACATTC GTCAGCTAAA CCCCGTCTGG CTGAGATCCA AGATTGGGAC AGTGAGTCAG 
GAGCCAGTCC TGTTCTCCTG CTCTGTCGCT GAGAACATTG CCTATGGAGC TGACAACCTC 
TCCTCGGTCA CAGCCCAGCA GGTGGAGAGG GCCGCAGAGG TGGCCAACGC CGCTGAGTTC 
ATCCGAAGCT TCCCACAGGG CTTCGACACT GTGGTCGGGG AGAAGGGCAT CCTCCTGTCA 
GGTGGGCAGA AGCAGAGGAT TGCAATAGCC AGAGCCCTGC TGAAGAACCC CAAAATTCTT 
CTCCTTGATG AAGCAACCAG TGCACTGGAT GCCGAAAATG AGCACCTGGT CCAGGAGGCC 
CTTGACCGGC TGATGGAAGG GAGAACCGTG CTGATCATAG CCCACCGCCT GTCCACCATT 
AAGAATGCCA ACTTTGTTGC TGTCCTTGAC CACGGAAAGA TCTGTGAACA CGGGACACAT 
GAAGAGCTGC TCCTGAAGCC CAATGGGCTT TACAGAAAAC TGATGAACAA GCAGAGTTTC 
CTGTCATATA ATGGAGCAGA GCAGTTCCTG GAACCTGCAC GGGCGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062425.1
CDS	310..2457
Translation	MRAPSARALLLIPRRGPAVRAWAPAVSSRIWLASEWTPLVRAWTSLIHKPGSGLRFPAPLSGLPGGVGQWATSSGARRCWVLAGPRAAHPLFARLQGAAATGVRDLGNDSQRRPAATGRSEVWKLLGLVRPERGRLSAAVGFLAVSSVITMSAPFFLGRIIDVIYTNPSEGYGDSLTRLCAVLTCVFLCGAAANGIRVYLMQSSGQSIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENLSDGLRAGAQASVGVGMMFFVSPSLATFVLSVVPPISVLAVIYGRYLRKLSKATQDSLAEATQLAEERIGNIRTIRAFGKEMTEVEKYTGRVDQLLQLAQKEALARAGFFGAAGLSGNLIVLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVGLSIGGLSSFYSELMKGLGAGGRLWELLERQPRLPFNEGMVLDEKTFQGALEFRNVHFTYPARPEVSVFQDFSLSIPSGSVTALVGPSGSGKSTVVSLLLRLYDPNSGTVSLDGHDIRQLNPVWLRSKIGTVSQEPVLFSCSVAENIAYGADNLSSVTAQQVERAAEVANAAEFIRSFPQGFDTVVGEKGILLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEHLVQEALDRLMEGRTVLIIAHRLSTIKNANFVAVLDHGKICEHGTHEELLLKPNGLYRKLMNKQSFLSYNGAEQFLEPARA

Target ORF information:

RefSeq Version	NM_019552.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 10 (Abcb10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019552.2

ORF Insert Sequence:

ATGCGCGCCC CTTCTGCTAG GGCGCTACTG CTGATTCCGC GTCGGGGCCC TGCCGTGCGA 
GCGTGGGCCC CGGCCGTCTC CTCTCGGATA TGGCTGGCTT CTGAATGGAC CCCGCTCGTA 
CGCGCGTGGA CCTCTCTGAT CCACAAGCCG GGTTCGGGCC TCCGCTTTCC CGCGCCCCTA 
TCCGGGCTGC CTGGCGGCGT GGGGCAGTGG GCCACCTCCT CGGGGGCCCG CAGGTGCTGG 
GTGCTGGCAG GACCCCGCGC CGCACATCCC CTGTTCGCCA GGCTCCAGGG TGCAGCTGCC 
ACCGGTGTGC GAGACCTTGG GAACGACTCG CAGCGGCGTC CCGCGGCGAC CGGGCGCTCA 
GAAGTATGGA AGCTCCTAGG GCTGGTGCGC CCCGAGCGCG GGAGACTGTC AGCTGCAGTT 
GGGTTTCTGG CTGTGTCCAG TGTCATCACC ATGTCTGCCC CCTTCTTCCT GGGAAGGATC 
ATTGATGTCA TCTATACCAA CCCAAGCGAG GGCTATGGCG ATAGCTTGAC TCGGCTCTGT 
GCTGTGCTCA CCTGTGTGTT CCTGTGCGGC GCTGCTGCCA ACGGCATTCG TGTCTACCTC 
ATGCAGTCTT CAGGTCAGAG CATTGTGAAC AGGCTGCGCA CCTCTCTGTT CTCCTCCATT 
CTAAGGCAAG AGGTTGCTTT CTTTGACAAG ACCCGCACAG GCGAATTAAT TAACCGCCTC 
TCCTCGGATA CCGCACTCCT GGGGCGCTCC GTGACTGAGA ACCTCTCCGA TGGCCTGAGA 
GCTGGGGCCC AGGCCTCCGT TGGTGTTGGC ATGATGTTTT TTGTGTCACC AAGTCTGGCC 
ACCTTTGTTC TGAGTGTGGT ACCGCCCATC TCTGTCCTCG CTGTGATTTA TGGGCGATAT 
CTACGGAAAC TGTCCAAAGC CACACAGGAC TCCTTGGCAG AAGCCACACA GCTAGCCGAG 
GAGCGGATTG GAAACATAAG AACCATCCGA GCTTTTGGGA AGGAGATGAC GGAAGTGGAG 
AAGTACACCG GCCGAGTGGA CCAGTTGCTG CAGCTGGCAC AGAAGGAGGC CTTGGCACGA 
GCCGGCTTCT TTGGAGCAGC TGGGCTCTCA GGAAACCTGA TTGTGCTGTC TGTCCTGTAC 
AAAGGAGGCC TGCTGATGGG CAGTGCCCAT ATGACAGTGG GCGAGCTCTC TTCCTTCCTC 
ATGTACGCTT TCTGGGTTGG ATTGAGCATC GGAGGACTGA GTTCATTCTA CTCCGAGCTG 
ATGAAAGGCC TGGGTGCTGG TGGGCGGCTC TGGGAGCTGC TGGAGAGACA GCCACGGCTG 
CCTTTTAACG AGGGGATGGT GTTAGATGAG AAAACCTTCC AGGGTGCCCT GGAGTTCAGA 
AACGTGCACT TCACATACCC TGCTCGCCCA GAGGTGTCCG TATTCCAGGA TTTCAGTCTT 
TCCATCCCAT CTGGATCTGT CACAGCGCTG GTTGGCCCAA GTGGTTCTGG GAAATCAACA 
GTGGTTTCGC TCCTGCTGCG GTTGTACGAC CCTAATTCTG GAACAGTCAG CCTTGATGGC 
CATGACATTC GTCAGCTAAA CCCCGTCTGG CTGAGATCCA AGATTGGGAC AGTGAGTCAG 
GAGCCAGTCC TGTTCTCCTG CTCTGTCGCT GAGAACATTG CCTATGGAGC TGACAACCTC 
TCCTCGGTCA CAGCCCAGCA GGTGGAGAGG GCCGCAGAGG TGGCCAACGC CGCTGAGTTC 
ATCCGAAGCT TCCCACAGGG CTTCGACACT GTGGTCGGGG AGAAGGGCAT CCTCCTGTCA 
GGTGGGCAGA AGCAGAGGAT TGCAATAGCC AGAGCCCTGC TGAAGAACCC CAAAATTCTT 
CTCCTTGATG AAGCAACCAG TGCACTGGAT GCCGAAAATG AGCACCTGGT CCAGGAGGCC 
CTTGACCGGC TGATGGAAGG GAGAACCGTG CTGATCATAG CCCACCGCCT GTCCACCATT 
AAGAATGCCA ACTTTGTTGC TGTCCTTGAC CACGGAAAGA TCTGTGAACA CGGGACACAT 
GAAGAGCTGC TCCTGAAGCC CAATGGGCTT TACAGAAAAC TGATGAACAA GCAGAGTTTC 
CTGTCATATA ATGGAGCAGA GCAGTTCCTG GAACCTGCAC GGGCGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Blood-brain barrier disruption in diabetic mice is linked to Nrf2 signaling deficits: Role of ABCB10?
Neuroscience letters653152-158(2017 Jul)
Sajja RK,Prasad S,Tang S,Kaisar MA,Cucullo L

Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs.
American journal of reproductive immunology (New York, N.Y. : 1989)74(3)237-57(2015 Sep)
Pan J,Mor G,Ju W,Zhong J,Luo X,Aldo PB,Zhong M,Yu Y,Jenkins EC,Brown WT,Zhong N

ATP Binding and Hydrolysis Properties of ABCB10 and Their Regulation by Glutathione.
PloS one10(6)e0129772(2015)
Qiu W,Liesa M,Carpenter EP,Shirihai OS

Abcb10 role in heme biosynthesis in vivo: Abcb10 knockout in mice causes anemia with protoporphyrin IX and iron accumulation.
Molecular and cellular biology34(6)1077-84(2014 Mar)
Yamamoto M,Arimura H,Fukushige T,Minami K,Nishizawa Y,Tanimoto A,Kanekura T,Nakagawa M,Akiyama S,Furukawa T

Snx3 regulates recycling of the transferrin receptor and iron assimilation.
Cell metabolism17(3)343-52(2013 Mar)
Chen C,Garcia-Santos D,Ishikawa Y,Seguin A,Li L,Fegan KH,Hildick-Smith GJ,Shah DI,Cooney JD,Chen W,King MJ,Yien YY,Schultz IJ,Anderson H,Dalton AJ,Freedman ML,Kingsley PD,Palis J,Hattangadi SM,Lodish HF,Ward DM,Kaplan J,Maeda T,Ponka P,Paw BH

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Abcb10 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報