Il17b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Il17b
Entrez Gene ID	56069
Full Name	interleukin 17B
Synonyms	1110006O16Rik,1700006N07Rik,Zcyto7
General protein information	Preferred Names interleukin 17B Names interleukin-17B IL-17B cytokine CX1 cytokine-like protein ZCYTO7 gene for cytokine-like protein neuronal interleukin-17-related factor
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 18 Map Location: 18\|18 E1

mRNA and Protein(s)

mRNA	Protein	Name
XM_030250543.1	XP_030106403.1	interleukin-17B isoform X2
XM_006526106.2	XP_006526169.1	interleukin-17B isoform X1
XM_006526108.4	XP_006526171.1	interleukin-17B isoform X2
XM_006526108.3	XP_006526171.1	interleukin-17B isoform X2
XM_006526106.3	XP_006526169.1	interleukin-17B isoform X1
NM_019508.1	NP_062381.1	interleukin-17B precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Il17b	NP_062381.1
Rattus norvegicus (Norway rat)	Il17b	NP_446241.1
	IL17B	XP_001106071.1
Gallus gallus (chicken)	IL17B	XP_004944894.1
Homo sapiens (human)	IL17B	NP_055258.1
Bos taurus (cattle)	IL17B	NP_001178974.1
Canis lupus familiaris (dog)	IL17B	XP_546311.1
Xenopus tropicalis (tropical clawed frog)	il17b	NP_001006699.1
Pan troglodytes (chimpanzee)	IL17B	XP_001163413.1

Gene Ontology
Bibliography

Related articles in PubMed

Interleukin-17B Antagonizes Interleukin-25-Mediated Mucosal Inflammation.
Reynolds JM, Lee YH, Shi Y, Wang X, Angkasekwinai P, Nallaparaju KC, Flaherty S, Chang SH, Watarai H, Dong C
Immunity42(4)692-703(2015 Apr)

Autocrine/paracrine mechanism of interleukin-17B receptor promotes breast tumorigenesis through NF-?B-mediated antiapoptotic pathway.
Huang CK, Yang CY, Jeng YM, Chen CL, Wu HH, Chang YC, Ma C, Kuo WH, Chang KJ, Shew JY, Lee WH
Oncogene33(23)2968-77(2014 Jun)

A mouse knockout library for secreted and transmembrane proteins.
Tang T, Li L, Tang J, Li Y, Lin WY, Martin F, Grant D, Solloway M, Parker L, Ye W, Forrest W, Ghilardi N, Oravecz T, Platt KA, Rice DS, Hansen GM, Abuin A, Eberhart DE, Godowski P, Holt KH, Peterson A, Zambrowicz BP, de Sauvage FJ
Nature biotechnology28(7)749-55(2010 Jul)

IL-17B and IL-17C are associated with TNF-alpha production and contribute to the exacerbation of inflammatory arthritis.
Yamaguchi Y, Fujio K, Shoda H, Okamoto A, Tsuno NH, Takahashi K, Yamamoto K
Journal of immunology (Baltimore, Md. : 1950)179(10)7128-36(2007 Nov)

Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells.
Chen Z, Laurence A, Kanno Y, Pacher-Zavisin M, Zhu BM, Tato C, Yoshimura A, Hennighausen L, O'Shea JJ
Proceedings of the National Academy of Sciences of the United States of America103(21)8137-42(2006 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interleukin-17B antagonizes interleukin-25-mediated mucosal inflammation.
Title: Interleukin-17B Antagonizes Interleukin-25-Mediated Mucosal Inflammation.

Results show that amplified signaling of interleukin-17 receptor B (IL-17RB) and its ligand IL-17B promot tumorigenicity in breast cancer cells and impeded acinus formation in immortalized normal mammary epithelial cells.
Title: Autocrine/paracrine mechanism of interleukin-17B receptor promotes breast tumorigenesis through NF-?B-mediated antiapoptotic pathway.

IL-17B and IL-17C play an important role in the pathogenesis of inflammatory arthritis.
Title: IL-17B and IL-17C are associated with TNF-alpha production and contribute to the exacerbation of inflammatory arthritis.

Socs3 is an essential negative regulator of IL-23 signaling, inhibition of which constrains the generation of IL-17-secreting T-cell differentiation
Title: Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells.

expressed in the mouse embryonic limb buds and may play a role in chondrogenesis and osteogenesis
Title: Expression of interleukin-17B in mouse embryonic limb buds and regulation by BMP-7 and bFGF.

The following Il17b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Il17b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu11146	NM_019508.1 Latest version!	Mus musculus interleukin 17B (Il17b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu54706	XM_006526106.3 Latest version!	Mus musculus interleukin 17B (Il17b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu54707	XM_006526108.4 Latest version!	Mus musculus interleukin 17B (Il17b), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu54707	XM_030250543.1 Latest version!	Mus musculus interleukin 17B (Il17b), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu54707	XM_006526108.3	Mus musculus interleukin 17B (Il17b), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu54706	XM_006526106.2	Mus musculus interleukin 17B (Il17b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Il17b ( XM_006526108.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006526171.1 Mus musculus interleukin 17B (Il17b), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu54707
Clone ID Related Accession (Same CDS sequence)	XM_030250543.1 , XM_006526108.4 , XM_006526108.3
Accession Version	XM_006526108.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 369bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	interleukin-17B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006526108.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGAGT ATGAGCGGAA CCTTGGGGAG ATGGTGGCCC AGCTGAGGAA CAGCTCCGAG 
CCAGCCAAGA AGAAATGTGA AGTCAATCTA CAGCTGTGGT TGTCCAACAA GAGGAGCCTG 
TCCCCATGGG GCTACAGCAT CAACCACGAC CCCAGCCGCA TCCCTGCGGA CTTGCCCGAG 
GCGCGGTGCC TATGTTTGGG TTGCGTGAAT CCCTTCACCA TGCAGGAGGA CCGTAGCATG 
GTGAGCGTGC CAGTGTTCAG CCAGGTGCCG GTGCGCCGCC GCCTCTGTCC TCAACCTCCT 
CGCCCTGGGC CCTGCCGCCA GCGTGTCGTC ATGGAGACCA TCGCTGTGGG TTGCACCTGC 
ATCTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006526171.1
CDS	599..967
Translation	MEEYERNLGEMVAQLRNSSEPAKKKCEVNLQLWLSNKRSLSPWGYSINHDPSRIPADLPEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPQPPRPGPCRQRVVMETIAVGCTCIF

Target ORF information:

RefSeq Version	XM_006526108.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus interleukin 17B (Il17b), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006526108.3

ORF Insert Sequence:

ATGGAAGAGT ATGAGCGGAA CCTTGGGGAG ATGGTGGCCC AGCTGAGGAA CAGCTCCGAG 
CCAGCCAAGA AGAAATGTGA AGTCAATCTA CAGCTGTGGT TGTCCAACAA GAGGAGCCTG 
TCCCCATGGG GCTACAGCAT CAACCACGAC CCCAGCCGCA TCCCTGCGGA CTTGCCCGAG 
GCGCGGTGCC TATGTTTGGG TTGCGTGAAT CCCTTCACCA TGCAGGAGGA CCGTAGCATG 
GTGAGCGTGC CAGTGTTCAG CCAGGTGCCG GTGCGCCGCC GCCTCTGTCC TCAACCTCCT 
CGCCCTGGGC CCTGCCGCCA GCGTGTCGTC ATGGAGACCA TCGCTGTGGG TTGCACCTGC 
ATCTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Il17b ( XM_006526106.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006526169.1 Mus musculus interleukin 17B (Il17b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu54706
Clone ID Related Accession (Same CDS sequence)	XM_006526106.2 , XM_006526106.3
Accession Version	XM_006526106.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 549bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	interleukin-17B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006526106.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGGTTG CTGCTGGCCT TGGTGCGCTC TTCCTCCTGG CCATCTCCAT CTTCCTGGCG 
CCAAGCCACC CCCGGAACAC CAAAGGCAAA AGAAAAGGGC AAGGGAGGCC CAGTCCCTTG 
GCCCCTGGGC CTCATCAGGT GCCGCTGGAC CTGGTGTCTC GAGTAAAGCC CTACGCTCGA 
ATGGAAGAGT ATGAGCGGAA CCTTGGGGAG ATGGTGGCCC AGCTGAGGAA CAGCTCCGAG 
CCAGCCAAGA AGAAATGTGA AGTCAATCTA CAGCTGTGGT TGTCCAACAA GAGGAGCCTG 
TCCCCATGGG GCTACAGCAT CAACCACGAC CCCAGCCGCA TCCCTGCGGA CTTGCCCGAG 
GCGCGGTGCC TATGTTTGGG TTGCGTGAAT CCCTTCACCA TGCAGGAGGA CCGTAGCATG 
GTGAGCGTGC CAGTGTTCAG CCAGGTGCCG GTGCGCCGCC GCCTCTGTCC TCAACCTCCT 
CGCCCTGGGC CCTGCCGCCA GCGTGTCGTC ATGGAGACCA TCGCTGTGGG TTGCACCTGC 
ATCTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006526169.1
CDS	409..957
Translation	MVVAAGLGALFLLAISIFLAPSHPRNTKGKRKGQGRPSPLAPGPHQVPLDLVSRVKPYARMEEYERNLGEMVAQLRNSSEPAKKKCEVNLQLWLSNKRSLSPWGYSINHDPSRIPADLPEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPQPPRPGPCRQRVVMETIAVGCTCIF

Target ORF information:

RefSeq Version	XM_006526106.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus interleukin 17B (Il17b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006526106.2

ORF Insert Sequence:

ATGGTGGTTG CTGCTGGCCT TGGTGCGCTC TTCCTCCTGG CCATCTCCAT CTTCCTGGCG 
CCAAGCCACC CCCGGAACAC CAAAGGCAAA AGAAAAGGGC AAGGGAGGCC CAGTCCCTTG 
GCCCCTGGGC CTCATCAGGT GCCGCTGGAC CTGGTGTCTC GAGTAAAGCC CTACGCTCGA 
ATGGAAGAGT ATGAGCGGAA CCTTGGGGAG ATGGTGGCCC AGCTGAGGAA CAGCTCCGAG 
CCAGCCAAGA AGAAATGTGA AGTCAATCTA CAGCTGTGGT TGTCCAACAA GAGGAGCCTG 
TCCCCATGGG GCTACAGCAT CAACCACGAC CCCAGCCGCA TCCCTGCGGA CTTGCCCGAG 
GCGCGGTGCC TATGTTTGGG TTGCGTGAAT CCCTTCACCA TGCAGGAGGA CCGTAGCATG 
GTGAGCGTGC CAGTGTTCAG CCAGGTGCCG GTGCGCCGCC GCCTCTGTCC TCAACCTCCT 
CGCCCTGGGC CCTGCCGCCA GCGTGTCGTC ATGGAGACCA TCGCTGTGGG TTGCACCTGC 
ATCTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Il17b ( NM_019508.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_062381.1 Mus musculus interleukin 17B (Il17b), mRNA.

Price & Availability↑

CloneID	OMu11146
Clone ID Related Accession (Same CDS sequence)	NM_019508.1
Accession Version	NM_019508.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 543bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	interleukin-17B precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF184970.1. ##Evidence-Data-START## Transcript exon combination :: AF184970.1, BC002271.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849377 [ECO:0000348] ##Evidence-Data-END##

ATGGACTGGC CGCACAGCCT GCTCTTCCTC CTGGCCATCT CCATCTTCCT GGCGCCAAGC 
CACCCCCGGA ACACCAAAGG CAAAAGAAAA GGGCAAGGGA GGCCCAGTCC CTTGGCCCCT 
GGGCCTCATC AGGTGCCGCT GGACCTGGTG TCTCGAGTAA AGCCCTACGC TCGAATGGAA 
GAGTATGAGC GGAACCTTGG GGAGATGGTG GCCCAGCTGA GGAACAGCTC CGAGCCAGCC 
AAGAAGAAAT GTGAAGTCAA TCTACAGCTG TGGTTGTCCA ACAAGAGGAG CCTGTCCCCA 
TGGGGCTACA GCATCAACCA CGACCCCAGC CGCATCCCTG CGGACTTGCC CGAGGCGCGG 
TGCCTATGTT TGGGTTGCGT GAATCCCTTC ACCATGCAGG AGGACCGTAG CATGGTGAGC 
GTGCCAGTGT TCAGCCAGGT GCCGGTGCGC CGCCGCCTCT GTCCTCAACC TCCTCGCCCT 
GGGCCCTGCC GCCAGCGTGT CGTCATGGAG ACCATCGCTG TGGGTTGCAC CTGCATCTTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062381.1
CDS	50..592
Translation	MDWPHSLLFLLAISIFLAPSHPRNTKGKRKGQGRPSPLAPGPHQVPLDLVSRVKPYARMEEYERNLGEMVAQLRNSSEPAKKKCEVNLQLWLSNKRSLSPWGYSINHDPSRIPADLPEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPQPPRPGPCRQRVVMETIAVGCTCIF

Target ORF information:

RefSeq Version	NM_019508.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus interleukin 17B (Il17b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019508.1

ORF Insert Sequence:

ATGGACTGGC CGCACAGCCT GCTCTTCCTC CTGGCCATCT CCATCTTCCT GGCGCCAAGC 
CACCCCCGGA ACACCAAAGG CAAAAGAAAA GGGCAAGGGA GGCCCAGTCC CTTGGCCCCT 
GGGCCTCATC AGGTGCCGCT GGACCTGGTG TCTCGAGTAA AGCCCTACGC TCGAATGGAA 
GAGTATGAGC GGAACCTTGG GGAGATGGTG GCCCAGCTGA GGAACAGCTC CGAGCCAGCC 
AAGAAGAAAT GTGAAGTCAA TCTACAGCTG TGGTTGTCCA ACAAGAGGAG CCTGTCCCCA 
TGGGGCTACA GCATCAACCA CGACCCCAGC CGCATCCCTG CGGACTTGCC CGAGGCGCGG 
TGCCTATGTT TGGGTTGCGT GAATCCCTTC ACCATGCAGG AGGACCGTAG CATGGTGAGC 
GTGCCAGTGT TCAGCCAGGT GCCGGTGCGC CGCCGCCTCT GTCCTCAACC TCCTCGCCCT 
GGGCCCTGCC GCCAGCGTGT CGTCATGGAG ACCATCGCTG TGGGTTGCAC CTGCATCTTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Il17b ( XM_006526106.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006526169.1 Mus musculus interleukin 17B (Il17b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu54706
Clone ID Related Accession (Same CDS sequence)	XM_006526106.2 , XM_006526106.3
Accession Version	XM_006526106.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 549bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	interleukin-17B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006526106.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGGTTG CTGCTGGCCT TGGTGCGCTC TTCCTCCTGG CCATCTCCAT CTTCCTGGCG 
CCAAGCCACC CCCGGAACAC CAAAGGCAAA AGAAAAGGGC AAGGGAGGCC CAGTCCCTTG 
GCCCCTGGGC CTCATCAGGT GCCGCTGGAC CTGGTGTCTC GAGTAAAGCC CTACGCTCGA 
ATGGAAGAGT ATGAGCGGAA CCTTGGGGAG ATGGTGGCCC AGCTGAGGAA CAGCTCCGAG 
CCAGCCAAGA AGAAATGTGA AGTCAATCTA CAGCTGTGGT TGTCCAACAA GAGGAGCCTG 
TCCCCATGGG GCTACAGCAT CAACCACGAC CCCAGCCGCA TCCCTGCGGA CTTGCCCGAG 
GCGCGGTGCC TATGTTTGGG TTGCGTGAAT CCCTTCACCA TGCAGGAGGA CCGTAGCATG 
GTGAGCGTGC CAGTGTTCAG CCAGGTGCCG GTGCGCCGCC GCCTCTGTCC TCAACCTCCT 
CGCCCTGGGC CCTGCCGCCA GCGTGTCGTC ATGGAGACCA TCGCTGTGGG TTGCACCTGC 
ATCTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006526169.1
CDS	528..1076
Translation	MVVAAGLGALFLLAISIFLAPSHPRNTKGKRKGQGRPSPLAPGPHQVPLDLVSRVKPYARMEEYERNLGEMVAQLRNSSEPAKKKCEVNLQLWLSNKRSLSPWGYSINHDPSRIPADLPEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPQPPRPGPCRQRVVMETIAVGCTCIF

Target ORF information:

RefSeq Version	XM_006526106.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus interleukin 17B (Il17b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006526106.3

ORF Insert Sequence:

ATGGTGGTTG CTGCTGGCCT TGGTGCGCTC TTCCTCCTGG CCATCTCCAT CTTCCTGGCG 
CCAAGCCACC CCCGGAACAC CAAAGGCAAA AGAAAAGGGC AAGGGAGGCC CAGTCCCTTG 
GCCCCTGGGC CTCATCAGGT GCCGCTGGAC CTGGTGTCTC GAGTAAAGCC CTACGCTCGA 
ATGGAAGAGT ATGAGCGGAA CCTTGGGGAG ATGGTGGCCC AGCTGAGGAA CAGCTCCGAG 
CCAGCCAAGA AGAAATGTGA AGTCAATCTA CAGCTGTGGT TGTCCAACAA GAGGAGCCTG 
TCCCCATGGG GCTACAGCAT CAACCACGAC CCCAGCCGCA TCCCTGCGGA CTTGCCCGAG 
GCGCGGTGCC TATGTTTGGG TTGCGTGAAT CCCTTCACCA TGCAGGAGGA CCGTAGCATG 
GTGAGCGTGC CAGTGTTCAG CCAGGTGCCG GTGCGCCGCC GCCTCTGTCC TCAACCTCCT 
CGCCCTGGGC CCTGCCGCCA GCGTGTCGTC ATGGAGACCA TCGCTGTGGG TTGCACCTGC 
ATCTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Il17b ( XM_030250543.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030106403.1 Mus musculus interleukin 17B (Il17b), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu54707
Clone ID Related Accession (Same CDS sequence)	XM_030250543.1 , XM_006526108.4 , XM_006526108.3
Accession Version	XM_030250543.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 369bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	interleukin-17B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGAGT ATGAGCGGAA CCTTGGGGAG ATGGTGGCCC AGCTGAGGAA CAGCTCCGAG 
CCAGCCAAGA AGAAATGTGA AGTCAATCTA CAGCTGTGGT TGTCCAACAA GAGGAGCCTG 
TCCCCATGGG GCTACAGCAT CAACCACGAC CCCAGCCGCA TCCCTGCGGA CTTGCCCGAG 
GCGCGGTGCC TATGTTTGGG TTGCGTGAAT CCCTTCACCA TGCAGGAGGA CCGTAGCATG 
GTGAGCGTGC CAGTGTTCAG CCAGGTGCCG GTGCGCCGCC GCCTCTGTCC TCAACCTCCT 
CGCCCTGGGC CCTGCCGCCA GCGTGTCGTC ATGGAGACCA TCGCTGTGGG TTGCACCTGC 
ATCTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030106403.1
CDS	301..669
Translation	MEEYERNLGEMVAQLRNSSEPAKKKCEVNLQLWLSNKRSLSPWGYSINHDPSRIPADLPEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPQPPRPGPCRQRVVMETIAVGCTCIF

Target ORF information:

RefSeq Version	XM_030250543.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus interleukin 17B (Il17b), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030250543.1

ORF Insert Sequence:

ATGGAAGAGT ATGAGCGGAA CCTTGGGGAG ATGGTGGCCC AGCTGAGGAA CAGCTCCGAG 
CCAGCCAAGA AGAAATGTGA AGTCAATCTA CAGCTGTGGT TGTCCAACAA GAGGAGCCTG 
TCCCCATGGG GCTACAGCAT CAACCACGAC CCCAGCCGCA TCCCTGCGGA CTTGCCCGAG 
GCGCGGTGCC TATGTTTGGG TTGCGTGAAT CCCTTCACCA TGCAGGAGGA CCGTAGCATG 
GTGAGCGTGC CAGTGTTCAG CCAGGTGCCG GTGCGCCGCC GCCTCTGTCC TCAACCTCCT 
CGCCCTGGGC CCTGCCGCCA GCGTGTCGTC ATGGAGACCA TCGCTGTGGG TTGCACCTGC 
ATCTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Il17b ( XM_006526108.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006526171.1 Mus musculus interleukin 17B (Il17b), transcript variant X2, mRNA.

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CloneID	OMu54707
Clone ID Related Accession (Same CDS sequence)	XM_030250543.1 , XM_006526108.4 , XM_006526108.3
Accession Version	XM_006526108.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 369bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	interleukin-17B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006526108.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGAGT ATGAGCGGAA CCTTGGGGAG ATGGTGGCCC AGCTGAGGAA CAGCTCCGAG 
CCAGCCAAGA AGAAATGTGA AGTCAATCTA CAGCTGTGGT TGTCCAACAA GAGGAGCCTG 
TCCCCATGGG GCTACAGCAT CAACCACGAC CCCAGCCGCA TCCCTGCGGA CTTGCCCGAG 
GCGCGGTGCC TATGTTTGGG TTGCGTGAAT CCCTTCACCA TGCAGGAGGA CCGTAGCATG 
GTGAGCGTGC CAGTGTTCAG CCAGGTGCCG GTGCGCCGCC GCCTCTGTCC TCAACCTCCT 
CGCCCTGGGC CCTGCCGCCA GCGTGTCGTC ATGGAGACCA TCGCTGTGGG TTGCACCTGC 
ATCTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006526171.1
CDS	209..577
Translation	MEEYERNLGEMVAQLRNSSEPAKKKCEVNLQLWLSNKRSLSPWGYSINHDPSRIPADLPEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPQPPRPGPCRQRVVMETIAVGCTCIF

Target ORF information:

RefSeq Version	XM_006526108.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus interleukin 17B (Il17b), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006526108.4

ORF Insert Sequence:

ATGGAAGAGT ATGAGCGGAA CCTTGGGGAG ATGGTGGCCC AGCTGAGGAA CAGCTCCGAG 
CCAGCCAAGA AGAAATGTGA AGTCAATCTA CAGCTGTGGT TGTCCAACAA GAGGAGCCTG 
TCCCCATGGG GCTACAGCAT CAACCACGAC CCCAGCCGCA TCCCTGCGGA CTTGCCCGAG 
GCGCGGTGCC TATGTTTGGG TTGCGTGAAT CCCTTCACCA TGCAGGAGGA CCGTAGCATG 
GTGAGCGTGC CAGTGTTCAG CCAGGTGCCG GTGCGCCGCC GCCTCTGTCC TCAACCTCCT 
CGCCCTGGGC CCTGCCGCCA GCGTGTCGTC ATGGAGACCA TCGCTGTGGG TTGCACCTGC 
ATCTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Interleukin-17B Antagonizes Interleukin-25-Mediated Mucosal Inflammation.
Immunity42(4)692-703(2015 Apr)
Reynolds JM,Lee YH,Shi Y,Wang X,Angkasekwinai P,Nallaparaju KC,Flaherty S,Chang SH,Watarai H,Dong C

Autocrine/paracrine mechanism of interleukin-17B receptor promotes breast tumorigenesis through NF-?B-mediated antiapoptotic pathway.
Oncogene33(23)2968-77(2014 Jun)
Huang CK,Yang CY,Jeng YM,Chen CL,Wu HH,Chang YC,Ma C,Kuo WH,Chang KJ,Shew JY,Lee WH

A mouse knockout library for secreted and transmembrane proteins.
Nature biotechnology28(7)749-55(2010 Jul)
Tang T,Li L,Tang J,Li Y,Lin WY,Martin F,Grant D,Solloway M,Parker L,Ye W,Forrest W,Ghilardi N,Oravecz T,Platt KA,Rice DS,Hansen GM,Abuin A,Eberhart DE,Godowski P,Holt KH,Peterson A,Zambrowicz BP,de Sauvage FJ

IL-17B and IL-17C are associated with TNF-alpha production and contribute to the exacerbation of inflammatory arthritis.
Journal of immunology (Baltimore, Md. : 1950)179(10)7128-36(2007 Nov)
Yamaguchi Y,Fujio K,Shoda H,Okamoto A,Tsuno NH,Takahashi K,Yamamoto K

Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells.
Proceedings of the National Academy of Sciences of the United States of America103(21)8137-42(2006 May)
Chen Z,Laurence A,Kanno Y,Pacher-Zavisin M,Zhu BM,Tato C,Yoshimura A,Hennighausen L,O'Shea JJ

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Il17b cDNA ORF clone, Mus musculus(house mouse)

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ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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