Defb48 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Defb48
Entrez Gene ID	432867
Full Name	defensin beta 48
Synonyms	Defb42,EG432867
General protein information	Preferred Names defensin beta 48 Names beta-defensin 48 beta-defensin 42
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 14 Map Location: 14 D1\|14

mRNA and Protein(s)

mRNA	Protein	Name
NM_001037751.3	NP_001032840.1	putative beta-defensin 109B precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Defb48	NP_001032840.1
Rattus norvegicus (Norway rat)	Defb42	NP_001032621.1
Pan troglodytes (chimpanzee)	LOC100170034	NP_001123231.1
	LOC695446	XP_001084318.1

Gene Ontology
Bibliography

Related articles in PubMed

Manual annotation and analysis of the defensin gene cluster in the C57BL/6J mouse reference genome.
Amid C, Rehaume LM, Brown KL, Gilbert JG, Dougan G, Hancock RE, Harrow JL
BMC genomics10606(2009 Dec)

Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract.
Patil AA, Cai Y, Sang Y, Blecha F, Zhang G
Physiological genomics23(1)5-17(2005 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Defb48 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Defb48 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu00065	NM_001037751.3 Latest version!	Mus musculus defensin beta 48 (Defb48), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Defb48 ( NM_001037751.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001032840.1 Mus musculus defensin beta 48 (Defb48), mRNA.

Price & Availability↑

CloneID	OMu00065
Clone ID Related Accession (Same CDS sequence)	NM_001037751.3
Accession Version	NM_001037751.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 264bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-09
Organism	Mus musculus(house mouse)
Product	putative beta-defensin 109B precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK136677.1 and BY721060.1. On Apr 29, 2010 this sequence version replaced NM_001037751.2. ##Evidence-Data-START## Transcript exon combination :: DQ012044.1, BY721060.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381 [ECO:0000348] ##Evidence-Data-END##

ATGAGACTGT ATCTGCTCCT CTCTACTCTA TTCTTCCTCT TGGACCTTTT ACCCCAAGTT 
AGAAGTGGGA TGGGTGCGTC TGAGACGCTC TGCGTCAGTC TGCAGGGCAC GTGCAGAAGA 
GACATCTGCA AACTGATAGA AGACGAGATC GGTGCTTGCC GGAGAAGATG GAAATGTTGC 
AGGCTGTGGT GGATTCTCAT ACCCATTCCA ACGCCAGTTA TCTTCTCAGA CTATCAAGAA 
CCCCTCCAGT CTAAGGTGAA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001032840.1
CDS	44..307
Translation	MRLYLLLSTLFFLLDLLPQVRSGMGASETLCVSLQGTCRRDICKLIEDEIGACRRRWKCCRLWWILIPIPTPVIFSDYQEPLQSKVK

Target ORF information:

RefSeq Version	NM_001037751.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus defensin beta 48 (Defb48), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001037751.3

ORF Insert Sequence:

ATGAGACTGT ATCTGCTCCT CTCTACTCTA TTCTTCCTCT TGGACCTTTT ACCCCAAGTT 
AGAAGTGGGA TGGGTGCGTC TGAGACGCTC TGCGTCAGTC TGCAGGGCAC GTGCAGAAGA 
GACATCTGCA AACTGATAGA AGACGAGATC GGTGCTTGCC GGAGAAGATG GAAATGTTGC 
AGGCTGTGGT GGATTCTCAT ACCCATTCCA ACGCCAGTTA TCTTCTCAGA CTATCAAGAA 
CCCCTCCAGT CTAAGGTGAA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Manual annotation and analysis of the defensin gene cluster in the C57BL/6J mouse reference genome.
BMC genomics10606(2009 Dec)
Amid C,Rehaume LM,Brown KL,Gilbert JG,Dougan G,Hancock RE,Harrow JL

Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract.
Physiological genomics23(1)5-17(2005 Sep)
Patil AA,Cai Y,Sang Y,Blecha F,Zhang G