Gjd3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gjd3
Entrez Gene ID	353155
Full Name	gap junction protein, delta 3
Synonyms	Gja11,Gjc1,cx30.2
General protein information	Preferred Names gap junction protein, delta 3 Names gap junction delta-3 protein connexin 30.2 gap junction alpha-11 protein gap junction chi-1 protein gap junction membrane channel protein chi 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11\|11 D

mRNA and Protein(s)

mRNA	Protein	Name
NM_178596.2	NP_848711.2	gap junction delta-3 protein
NM_178596.3	NP_848711.2	gap junction delta-3 protein

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	gjd3	XP_002940263.1
Pan troglodytes (chimpanzee)	GJD3	XP_003315500.1
	GJD3	XP_001097309.1
Rattus norvegicus (Norway rat)	Gjd3	XP_006247504.1
Canis lupus familiaris (dog)	GJD3	XP_003639318.1
Mus musculus (house mouse)	Gjd3	NP_848711.2
Homo sapiens (human)	GJD3	NP_689343.3
Bos taurus (cattle)	GJD3	XP_005220837.1

Gene Ontology
Bibliography

Related articles in PubMed

MyoR modulates cardiac conduction by repressing Gata4.
Harris JP, Bhakta M, Bezprozvannaya S, Wang L, Lubczyk C, Olson EN, Munshi NV
Molecular and cellular biology35(4)649-61(2015 Feb)

Connexin 30.2 is expressed in mouse pancreatic beta cells.
Coronel-Cruz C, Hern?ndez-Tellez B, L?pez-Vancell R, L?pez-Vidal Y, Berumen J, Castell A, P?rez-Armendariz EM
Biochemical and biophysical research communications438(4)772-7(2013 Sep)

Connexin45 provides optimal atrioventricular nodal conduction in the adult mouse heart.
Frank M, Wirth A, Andri? RP, Kreuzberg MM, Dobrowolski R, Seifert G, Offermanns S, Nickenig G, Willecke K, Schrickel JW
Circulation research111(12)1528-38(2012 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Significant reduction of Cx30.2 mRNA was found in islets preparations incubated for 24h in 22mM as compared with 3.3mM glucose.
Title: Connexin 30.2 is expressed in mouse pancreatic beta cells.

The data of this stiudy provided evidence that coupling of RG A1 cells to displaced amacrine cells is mediated by Cx30.2 and that the extent of this coupling is modulated by protein kinase C.
Title: Expression and modulation of connexin 30.2, a novel gap junction protein in the mouse retina.

A distal enhancer for the connexin 30.2 (Cx30.2, also known as Gjd3) gene required for normal atrioventricular (AV) delay in mice, is necessary and sufficient to direct expression to the developing AV conduction system, which is alos dependent on Gata4.
Title: Cx30.2 enhancer analysis identifies Gata4 as a novel regulator of atrioventricular delay.

Cx30.2 and Cx40 act as counterparts in the AV-node and His-bundle, decreasing or increasing, respectively, electrical coupling and conduction velocity in these areas.
Title: Normal impulse propagation in the atrioventricular conduction system of Cx30.2/Cx40 double deficient mice.

In the hippocampus, co-immunofluorescence analyses revealed beta-galactosidase/Cx30.2 expression in GABAergic inhibitory interneurons such as parvalbumin- and somatostatin-positive basket, axo-axonic, bistratified or oriens lacunosum-moleculare cells.
Title: Expression of connexin30.2 in interneurons of the central nervous system in the mouse.

The following Gjd3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gjd3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu13107	NM_178596.3 Latest version!	Mus musculus gap junction protein, delta 3 (Gjd3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00
View Old Accession Versions >>
OMu13107	NM_178596.2	Mus musculus gap junction protein, delta 3 (Gjd3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gjd3 ( NM_178596.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_848711.2 Mus musculus gap junction protein, delta 3 (Gjd3), mRNA.

Price & Availability↑

CloneID	OMu13107
Clone ID Related Accession (Same CDS sequence)	NM_178596.2 , NM_178596.3
Accession Version	NM_178596.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 837bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Mus musculus(house mouse)
Product	gap junction delta-3 protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL591067.35. On Oct 14, 2006 this sequence version replaced NM_178596.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

ATGGGGGAGT GGGCGTTCCT AGGCTCCCTG CTGGACGCGG TGCAGCTACA GTCGCCGCTC 
GTGGGTCGTC TCTGGCTGGT GATCATGCTG ATCTTCCGCA TCCTGGTGCT GGCCACGGTG 
GGAGGTGCGG TGTTCGAGGA CGAGCAGGAG GAGTTCGTGT GTAACACGTT GCAGCCCGGC 
TGTCGCCAGA CCTGCTACGA TCGCGCCTTC CCGGTGTCCC ACTACCGCTT CTGGCTCTTC 
CACATCCTGC TGCTGTCGGC GCCGCCGGTG CTGTTCGTCA TCTACTCCAT GCACCAGGCC 
AGCAAGGAGG CGGGTGGTGC GCAGCTGGCC CCGCCGTGCG CGCGCGGGCG TGCCGAGGCG 
CCGTGCTCCC CGTGCGCCCT GCGCGCTCGC CGCGCGCGCC GCTGCTACCT GCTGAGCGTG 
GCTCTGCGCC TGCTCGCCGA GCTGGCTTTC CTGGGCGGCC AGGCGCTGCT CTACGGCTTC 
CGCGTGGACC CGCACTACGC GTGCGCCGGG CCACCTTGTC CGCACACGGT CGACTGTTTC 
GTGAGCCGGC CCACCGAGAA GACCGTCTTC GTGGTCTTCT ACTTCGCCGT CGGGCTGCTG 
TCGGCGCTGC TCAGCGTGGC GGAGCTGGGT CACCTGCTCT GGAAGGGTCG CCAGCGCGCC 
AAGCTGCTCC CGCCGCCGCC GCCGTCGCCC TCTTTGCCAT CGCAGCGCGG GGACCCCGAC 
CCTTTCGGCC CGCCAGCCTA CGCGCACCGC TCACCGGCAG GCGACAGCGA GGGCGAAGGC 
GGCAGCGGCC ACAGCAAAGC GTCGCTGGCT ACCGTGCGCC AGGACCTGGC CATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_848711.2
CDS	1..837
Translation	MGEWAFLGSLLDAVQLQSPLVGRLWLVIMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVIYSMHQASKEAGGAQLAPPCARGRAEAPCSPCALRARRARRCYLLSVALRLLAELAFLGGQALLYGFRVDPHYACAGPPCPHTVDCFVSRPTEKTVFVVFYFAVGLLSALLSVAELGHLLWKGRQRAKLLPPPPPSPSLPSQRGDPDPFGPPAYAHRSPAGDSEGEGGSGHSKASLATVRQDLAI

Target ORF information:

RefSeq Version	NM_178596.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus gap junction protein, delta 3 (Gjd3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_178596.2

ORF Insert Sequence:

ATGGGGGAGT GGGCGTTCCT AGGCTCCCTG CTGGACGCGG TGCAGCTACA GTCGCCGCTC 
GTGGGTCGTC TCTGGCTGGT GATCATGCTG ATCTTCCGCA TCCTGGTGCT GGCCACGGTG 
GGAGGTGCGG TGTTCGAGGA CGAGCAGGAG GAGTTCGTGT GTAACACGTT GCAGCCCGGC 
TGTCGCCAGA CCTGCTACGA TCGCGCCTTC CCGGTGTCCC ACTACCGCTT CTGGCTCTTC 
CACATCCTGC TGCTGTCGGC GCCGCCGGTG CTGTTCGTCA TCTACTCCAT GCACCAGGCC 
AGCAAGGAGG CGGGTGGTGC GCAGCTGGCC CCGCCGTGCG CGCGCGGGCG TGCCGAGGCG 
CCGTGCTCCC CGTGCGCCCT GCGCGCTCGC CGCGCGCGCC GCTGCTACCT GCTGAGCGTG 
GCTCTGCGCC TGCTCGCCGA GCTGGCTTTC CTGGGCGGCC AGGCGCTGCT CTACGGCTTC 
CGCGTGGACC CGCACTACGC GTGCGCCGGG CCACCTTGTC CGCACACGGT CGACTGTTTC 
GTGAGCCGGC CCACCGAGAA GACCGTCTTC GTGGTCTTCT ACTTCGCCGT CGGGCTGCTG 
TCGGCGCTGC TCAGCGTGGC GGAGCTGGGT CACCTGCTCT GGAAGGGTCG CCAGCGCGCC 
AAGCTGCTCC CGCCGCCGCC GCCGTCGCCC TCTTTGCCAT CGCAGCGCGG GGACCCCGAC 
CCTTTCGGCC CGCCAGCCTA CGCGCACCGC TCACCGGCAG GCGACAGCGA GGGCGAAGGC 
GGCAGCGGCC ACAGCAAAGC GTCGCTGGCT ACCGTGCGCC AGGACCTGGC CATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gjd3 ( NM_178596.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_848711.2 Mus musculus gap junction protein, delta 3 (Gjd3), mRNA.

Price & Availability↑

CloneID	OMu13107
Clone ID Related Accession (Same CDS sequence)	NM_178596.2 , NM_178596.3
Accession Version	NM_178596.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 837bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Mus musculus(house mouse)
Product	gap junction delta-3 protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL591067.35. On Jun 21, 2019 this sequence version replaced NM_178596.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

ATGGGGGAGT GGGCGTTCCT AGGCTCCCTG CTGGACGCGG TGCAGCTACA GTCGCCGCTC 
GTGGGTCGTC TCTGGCTGGT GATCATGCTG ATCTTCCGCA TCCTGGTGCT GGCCACGGTG 
GGAGGTGCGG TGTTCGAGGA CGAGCAGGAG GAGTTCGTGT GTAACACGTT GCAGCCCGGC 
TGTCGCCAGA CCTGCTACGA TCGCGCCTTC CCGGTGTCCC ACTACCGCTT CTGGCTCTTC 
CACATCCTGC TGCTGTCGGC GCCGCCGGTG CTGTTCGTCA TCTACTCCAT GCACCAGGCC 
AGCAAGGAGG CGGGTGGTGC GCAGCTGGCC CCGCCGTGCG CGCGCGGGCG TGCCGAGGCG 
CCGTGCTCCC CGTGCGCCCT GCGCGCTCGC CGCGCGCGCC GCTGCTACCT GCTGAGCGTG 
GCTCTGCGCC TGCTCGCCGA GCTGGCTTTC CTGGGCGGCC AGGCGCTGCT CTACGGCTTC 
CGCGTGGACC CGCACTACGC GTGCGCCGGG CCACCTTGTC CGCACACGGT CGACTGTTTC 
GTGAGCCGGC CCACCGAGAA GACCGTCTTC GTGGTCTTCT ACTTCGCCGT CGGGCTGCTG 
TCGGCGCTGC TCAGCGTGGC GGAGCTGGGT CACCTGCTCT GGAAGGGTCG CCAGCGCGCC 
AAGCTGCTCC CGCCGCCGCC GCCGTCGCCC TCTTTGCCAT CGCAGCGCGG GGACCCCGAC 
CCTTTCGGCC CGCCAGCCTA CGCGCACCGC TCACCGGCAG GCGACAGCGA GGGCGAAGGC 
GGCAGCGGCC ACAGCAAAGC GTCGCTGGCT ACCGTGCGCC AGGACCTGGC CATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_848711.2
CDS	5..841
Translation	MGEWAFLGSLLDAVQLQSPLVGRLWLVIMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVIYSMHQASKEAGGAQLAPPCARGRAEAPCSPCALRARRARRCYLLSVALRLLAELAFLGGQALLYGFRVDPHYACAGPPCPHTVDCFVSRPTEKTVFVVFYFAVGLLSALLSVAELGHLLWKGRQRAKLLPPPPPSPSLPSQRGDPDPFGPPAYAHRSPAGDSEGEGGSGHSKASLATVRQDLAI

Target ORF information:

RefSeq Version	NM_178596.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus gap junction protein, delta 3 (Gjd3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_178596.3

ORF Insert Sequence:

ATGGGGGAGT GGGCGTTCCT AGGCTCCCTG CTGGACGCGG TGCAGCTACA GTCGCCGCTC 
GTGGGTCGTC TCTGGCTGGT GATCATGCTG ATCTTCCGCA TCCTGGTGCT GGCCACGGTG 
GGAGGTGCGG TGTTCGAGGA CGAGCAGGAG GAGTTCGTGT GTAACACGTT GCAGCCCGGC 
TGTCGCCAGA CCTGCTACGA TCGCGCCTTC CCGGTGTCCC ACTACCGCTT CTGGCTCTTC 
CACATCCTGC TGCTGTCGGC GCCGCCGGTG CTGTTCGTCA TCTACTCCAT GCACCAGGCC 
AGCAAGGAGG CGGGTGGTGC GCAGCTGGCC CCGCCGTGCG CGCGCGGGCG TGCCGAGGCG 
CCGTGCTCCC CGTGCGCCCT GCGCGCTCGC CGCGCGCGCC GCTGCTACCT GCTGAGCGTG 
GCTCTGCGCC TGCTCGCCGA GCTGGCTTTC CTGGGCGGCC AGGCGCTGCT CTACGGCTTC 
CGCGTGGACC CGCACTACGC GTGCGCCGGG CCACCTTGTC CGCACACGGT CGACTGTTTC 
GTGAGCCGGC CCACCGAGAA GACCGTCTTC GTGGTCTTCT ACTTCGCCGT CGGGCTGCTG 
TCGGCGCTGC TCAGCGTGGC GGAGCTGGGT CACCTGCTCT GGAAGGGTCG CCAGCGCGCC 
AAGCTGCTCC CGCCGCCGCC GCCGTCGCCC TCTTTGCCAT CGCAGCGCGG GGACCCCGAC 
CCTTTCGGCC CGCCAGCCTA CGCGCACCGC TCACCGGCAG GCGACAGCGA GGGCGAAGGC 
GGCAGCGGCC ACAGCAAAGC GTCGCTGGCT ACCGTGCGCC AGGACCTGGC CATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MyoR modulates cardiac conduction by repressing Gata4.
Molecular and cellular biology35(4)649-61(2015 Feb)
Harris JP,Bhakta M,Bezprozvannaya S,Wang L,Lubczyk C,Olson EN,Munshi NV

Connexin 30.2 is expressed in mouse pancreatic beta cells.
Biochemical and biophysical research communications438(4)772-7(2013 Sep)
Coronel-Cruz C,Hern?ndez-Tellez B,L?pez-Vancell R,L?pez-Vidal Y,Berumen J,Castell A,P?rez-Armendariz EM

Connexin45 provides optimal atrioventricular nodal conduction in the adult mouse heart.
Circulation research111(12)1528-38(2012 Dec)
Frank M,Wirth A,Andri? RP,Kreuzberg MM,Dobrowolski R,Seifert G,Offermanns S,Nickenig G,Willecke K,Schrickel JW

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Gjd3 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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