The following Mical2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mical2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu06153 | |
| Clone ID Related Accession (Same CDS sequence) | NM_177282.5 | |
| Accession Version | NM_177282.5 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2883bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-21 | |
| Organism | Mus musculus(house mouse) | |
| Product | [F-actin]-monooxygenase MICAL2 isoform B | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB662540.1, AK030608.1 and AC132392.3. On Jul 21, 2010 this sequence version replaced NM_177282.4. Transcript Variant: This variant (B) lacks 5 alternate exons, resulting in the loss of an in-frame segment in the 3' coding region, and uses an alternate splice site in the 3' coding region, compared to variant 1. The resulting protein (isoform B) is shorter and has a distinct C-terminus, compared to isoform A. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK143191.1, AK030608.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGGAGAGA ATGAAGATGA GAAGCAGGCG CAGGCCAGCC AGGTCTTCGA GAACTTTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_796256.1 |
| CDS | 336..3218 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_177282.5 |
1 | ATGGGAGAGA ATGAAGATGA GAAGCAGGCG CAGGCCAGCC AGGTCTTCGA GAACTTTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu89535 | |
| Clone ID Related Accession (Same CDS sequence) | XM_030242685.1 | |
| Accession Version | XM_030242685.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2628bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-07 | |
| Organism | Mus musculus(house mouse) | |
| Product | F-actin-monooxygenase MICAL2 isoform X2 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGGAGAGA ATGAAGATGA GAAGCAGGCG CAGGCCAGCC AGGTCTTCGA GAACTTTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_030098545.1 |
| CDS | 347..2974 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_030242685.1 |
1 | ATGGGAGAGA ATGAAGATGA GAAGCAGGCG CAGGCCAGCC AGGTCTTCGA GAACTTTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu01446 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006507954.2 , NM_001193305.1 , XM_006507954.1 | |
| Accession Version | XM_006507954.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3309bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-07 | |
| Organism | Mus musculus(house mouse) | |
| Product | F-actin-monooxygenase MICAL2 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006507954.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGGAGAGA ATGAAGATGA GAAGCAGGCG CAGGCCAGCC AGGTCTTCGA GAACTTTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006508017.1 |
| CDS | 347..3655 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006507954.2 |
1 | ATGGGAGAGA ATGAAGATGA GAAGCAGGCG CAGGCCAGCC AGGTCTTCGA GAACTTTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu01446 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006507954.2 , NM_001193305.1 , XM_006507954.1 | |
| Accession Version | NM_001193305.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3309bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-21 | |
| Organism | Mus musculus(house mouse) | |
| Product | [F-actin]-monooxygenase MICAL2 isoform A | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC166834.2, AC100153.10 and AC132392.3. Transcript Variant: This variant (A) encodes the longer isoform (A). Sequence Note: This RefSeq record was created from genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## CDS exon combination :: AK220353.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849387 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGGAGAGA ATGAAGATGA GAAGCAGGCG CAGGCCAGCC AGGTCTTCGA GAACTTTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001180234.1 |
| CDS | 336..3644 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001193305.1 |
1 | ATGGGAGAGA ATGAAGATGA GAAGCAGGCG CAGGCCAGCC AGGTCTTCGA GAACTTTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu01446 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006507954.2 , NM_001193305.1 , XM_006507954.1 | |
| Accession Version | XM_006507954.1 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3309bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-06-21 | |
| Organism | Mus musculus(house mouse) | |
| Product | protein-methionine sulfoxide oxidase MICAL2 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGGAGAGA ATGAAGATGA GAAGCAGGCG CAGGCCAGCC AGGTCTTCGA GAACTTTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006508017.1 |
| CDS | 331..3639 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006507954.1 |
1 | ATGGGAGAGA ATGAAGATGA GAAGCAGGCG CAGGCCAGCC AGGTCTTCGA GAACTTTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Actin stimulates reduction of the MICAL-2 monooxygenase domain. |
MsrB1 and MICALs regulate actin assembly and macrophage function via reversible stereoselective methionine oxidation. |
The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map. |
MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion. |
