Npsr1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Npsr1
Entrez Gene ID	319239
Full Name	neuropeptide S receptor 1
Synonyms	9330128H10Rik,GPRA,Gpr154,MVTR,PGR14,VRR1
General protein information	Preferred Names neuropeptide S receptor 1 Names neuropeptide S receptor G protein-coupled receptor 154 G protein-coupled receptor PGR14 vasotocin receptor
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9\|9 A3-A4

mRNA and Protein(s)

mRNA	Protein	Name
NM_175678.3	NP_783609.1	neuropeptide S receptor
XM_017313418.1	XP_017168907.1	neuropeptide S receptor isoform X2
XM_006510402.2	XP_006510465.1	neuropeptide S receptor isoform X1
XM_017313417.1	XP_017168906.1	neuropeptide S receptor isoform X1
XM_017313417.2	XP_017168906.1	neuropeptide S receptor isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	NPSR1	XP_001168820.1
Bos taurus (cattle)	NPSR1	NP_001179906.1
Rattus norvegicus (Norway rat)	Npsr1	NP_001100278.1
Homo sapiens (human)	NPSR1	NP_997055.1
	NPSR1	NP_001028114.1
Drosophila melanogaster (fruit fly)	CcapR	NP_996297.3
Canis lupus familiaris (dog)	NPSR1	XP_539511.2
Gallus gallus (chicken)	NPSR1	XP_426022.2
Anopheles gambiae (African malaria mosquito)	GPRVPR1	XP_321100.4
Mus musculus (house mouse)	Npsr1	NP_783609.1
Xenopus tropicalis (tropical clawed frog)	npsr1	XP_002937035.2

Gene Ontology
Bibliography

Related articles in PubMed

Neuropeptide S ameliorates olfactory spatial memory impairment induced by scopolamine and MK801 through activation of cognate receptor-expressing neurons in the subiculum complex.
Shao YF, Wang C, Xie JF, Kong XP, Xin L, Dong CY, Li J, Ren WT, Hou YP
Brain structure & function221(6)3327-36(2016 07)

Neuropeptide S reduces mouse aggressiveness in the resident/intruder test through selective activation of the neuropeptide S receptor.
Ruzza C, Asth L, Guerrini R, Trapella C, Gavioli EC
Neuropharmacology971-6(2015 Oct)

Selective breeding for high anxiety introduces a synonymous SNP that increases neuropeptide S receptor activity.
Slattery DA, Naik RR, Grund T, Yen YC, Sartori SB, F?chsl A, Finger BC, Elfving B, Nordemann U, Guerrini R, Calo G, Wegener G, Math? AA, Singewald N, Czibere L, Landgraf R, Neumann ID
The Journal of neuroscience : the official journal of the Society for Neuroscience35(11)4599-613(2015 Mar)

Paradoxical response to the sedative effects of diazepam and alcohol in C57BL/6J mice lacking the neuropeptide S receptor.
Ghazal P, Corsi M, Roth A, Faggioni F, Corti C, Merlo Pick E, Pucciarelli S, Ciccocioppo R, Ubaldi M
Peptides61107-13(2014 Nov)

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A, Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR
Neuron83(2)309-323(2014 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Findings demonstrate that neuropeptide S, via selective activation of the neurons bearing neuropeptide S receptor in the subiculum complex, ameliorates olfactory spatial memory impairment induced by scopolamine and MK801 in mice.
Title: Neuropeptide S ameliorates olfactory spatial memory impairment induced by scopolamine and MK801 through activation of cognate receptor-expressing neurons in the subiculum complex.

Study demonstrated that NPS produces anti-aggressive effects in mice through the selective activation of NPSR and that the endogenous NPS/NPSR system can exert a role in the control of aggressiveness levels under the present experimental conditions
Title: Neuropeptide S reduces mouse aggressiveness in the resident/intruder test through selective activation of the neuropeptide S receptor.

A single nucleotide polymorphism in Npsr1 that increases its activity is linked to higher anxiety.
Title: Selective breeding for high anxiety introduces a synonymous SNP that increases neuropeptide S receptor activity.

the deletion of NPSR did not lead to compensatory changes in the vigilance-promoting effects of the CRF and Hcrt-1/Ox-A systems.
Title: Paradoxical response to the sedative effects of diazepam and alcohol in C57BL/6J mice lacking the neuropeptide S receptor.

In conclusion, the present study indicates that the NPS/NPSR system does not tonically control locomotion, sensitivity to diazepam, anxiety, depressive-like behaviours, memory and pain transmission in mice.
Title: Behavioural phenotypic characterization of CD-1 mice lacking the neuropeptide S receptor.

The following Npsr1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Npsr1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu82849	XM_017313418.1 Latest version!	Mus musculus neuropeptide S receptor 1 (Npsr1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu20028	NM_175678.3 Latest version!	Mus musculus neuropeptide S receptor 1 (Npsr1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OMu20028	XM_006510402.2 Latest version!	Mus musculus neuropeptide S receptor 1 (Npsr1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OMu20028	XM_017313417.2 Latest version!	Mus musculus neuropeptide S receptor 1 (Npsr1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OMu20028	XM_017313417.1	Mus musculus neuropeptide S receptor 1 (Npsr1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Npsr1 ( XM_017313418.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017168907.1 Mus musculus neuropeptide S receptor 1 (Npsr1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu82849
Clone ID Related Accession (Same CDS sequence)	XM_017313418.1
Accession Version	XM_017313418.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 657bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	neuropeptide S receptor isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGTTTC TTCAAGGAGA GAAGCAAGCC AAAGTCCTCA TCGGAATAGC GTGGAGCCTC 
TCGTTCCTGT TCTCCATTCC CACGCTGATC ATATTTGGGA AAAGGACACT TTCCAATGGT 
GAGGTGCAGT GCTGGGCACT GTGGCCGGAT GACTCCTACT GGACCCCGTA CATGACCATC 
GTCGCCTTTC TGGTGTACTT CATTCCCTTG GCAATTATCA GCGTTATCTA TGGCCTTGTG 
ATCCGAACTA TTTGGATGAA AAGCAAAACC CATGAGACGG TGATTTCCAA CTGCTCAGAT 
GGCAAACTAT GCTGCAGCTA CAACCGAGGG CTCATCTCTA AGGCAAAAAT CAAGGCCATC 
AAGTATAGCA TCGTCATAAT CCTTGCTTTC ATCTGCTGCT GGAGCCCATA CTTCCTCTTT 
GACATATTAG ACAACTTCAA CGTCCTTCCA GACACCAAGG AGCGTTTCTA TGCCTCTGTG 
ATTATCCAGA ACCTGCCCGC CTTGAACAGT GCCATTAACC CCCTCATCTA CTGCATCTTC 
AGCAGCTCCA TCTGCTCCCC CTGCAAGATG CAAAGATCAC AGGATTCCAG AATGACATAC 
CGAGAGAGAA GCGAGAGACA CGAGATGCAG ATTCTCTCCA AGCCGGAATT CATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017168907.1
CDS	147..803
Translation	MKFLQGEKQAKVLIGIAWSLSFLFSIPTLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLAIISVIYGLVIRTIWMKSKTHETVISNCSDGKLCCSYNRGLISKAKIKAIKYSIVIILAFICCWSPYFLFDILDNFNVLPDTKERFYASVIIQNLPALNSAINPLIYCIFSSSICSPCKMQRSQDSRMTYRERSERHEMQILSKPEFI

Target ORF information:

RefSeq Version	XM_017313418.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus neuropeptide S receptor 1 (Npsr1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017313418.1

ORF Insert Sequence:

ATGAAGTTTC TTCAAGGAGA GAAGCAAGCC AAAGTCCTCA TCGGAATAGC GTGGAGCCTC 
TCGTTCCTGT TCTCCATTCC CACGCTGATC ATATTTGGGA AAAGGACACT TTCCAATGGT 
GAGGTGCAGT GCTGGGCACT GTGGCCGGAT GACTCCTACT GGACCCCGTA CATGACCATC 
GTCGCCTTTC TGGTGTACTT CATTCCCTTG GCAATTATCA GCGTTATCTA TGGCCTTGTG 
ATCCGAACTA TTTGGATGAA AAGCAAAACC CATGAGACGG TGATTTCCAA CTGCTCAGAT 
GGCAAACTAT GCTGCAGCTA CAACCGAGGG CTCATCTCTA AGGCAAAAAT CAAGGCCATC 
AAGTATAGCA TCGTCATAAT CCTTGCTTTC ATCTGCTGCT GGAGCCCATA CTTCCTCTTT 
GACATATTAG ACAACTTCAA CGTCCTTCCA GACACCAAGG AGCGTTTCTA TGCCTCTGTG 
ATTATCCAGA ACCTGCCCGC CTTGAACAGT GCCATTAACC CCCTCATCTA CTGCATCTTC 
AGCAGCTCCA TCTGCTCCCC CTGCAAGATG CAAAGATCAC AGGATTCCAG AATGACATAC 
CGAGAGAGAA GCGAGAGACA CGAGATGCAG ATTCTCTCCA AGCCGGAATT CATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Npsr1 ( NM_175678.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_783609.1 Mus musculus neuropeptide S receptor 1 (Npsr1), mRNA.

Price & Availability↑

CloneID	OMu20028
Clone ID Related Accession (Same CDS sequence)	NM_175678.3 , XM_006510402.2 , XM_017313417.1 , XM_017313417.2
Accession Version	NM_175678.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1116bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Mus musculus(house mouse)
Product	neuropeptide S receptor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK033957.1. On Apr 6, 2007 this sequence version replaced NM_175678.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK033957.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849383, SAMN00849384 [ECO:0000350] ##Evidence-Data-END##

ATGCCAGCCA ACCTCACAGA GGGCAGCTTT CATGCCAACC AGACTGTGCC GATGCTAGAT 
TCTTCCCCAG TAGCTTGCAC TGAAATTGTG ACGTTCACTG AAGCACTGGT GGCTGAGGAG 
TGGGGCTCCT TCTACTCCTC CTTTAAGACA GAACAGCTGA TAACCCTGTG GGTCCTGTTT 
GTCGTCACTA TTGTGGGAAA CTCTGTTGTG CTGTTCTCCA CGTGCAGAAG AAAAAGAAAG 
TCCAGAATGA CCTTCTTTGT GACACAATTG GCCATCACAG ACTCCTTCAC GGGCCTGATC 
AACATCTTGA CAGACATTAT TTGGCGATTC ACAGGAGACT TCATGGCCCC TGACCTGGTT 
TGCAGAGTCG TCCGCTACTT GCAGGTTGTC CTGCTGTATG CCTCTACCTA CGTCCTGGTG 
TCCCTCAGCA TAGACAGATA CCATGCCATC GTTTACCCCA TGAAGTTTCT TCAAGGAGAG 
AAGCAAGCCA AAGTCCTCAT CGGAATAGCG TGGAGCCTCT CGTTCCTGTT CTCCATTCCC 
ACGCTGATCA TATTTGGGAA AAGGACACTT TCCAATGGTG AGGTGCAGTG CTGGGCACTG 
TGGCCGGATG ACTCCTACTG GACCCCGTAC ATGACCATCG TCGCCTTTCT GGTGTACTTC 
ATTCCCTTGG CAATTATCAG CGTTATCTAT GGCCTTGTGA TCCGAACTAT TTGGATGAAA 
AGCAAAACCC ATGAGACGGT GATTTCCAAC TGCTCAGATG GCAAACTATG CTGCAGCTAC 
AACCGAGGGC TCATCTCTAA GGCAAAAATC AAGGCCATCA AGTATAGCAT CGTCATAATC 
CTTGCTTTCA TCTGCTGCTG GAGCCCATAC TTCCTCTTTG ACATATTAGA CAACTTCAAC 
GTCCTTCCAG ACACCAAGGA GCGTTTCTAT GCCTCTGTGA TTATCCAGAA CCTGCCCGCC 
TTGAACAGTG CCATTAACCC CCTCATCTAC TGCATCTTCA GCAGCTCCAT CTGCTCCCCC 
TGCAAGATGC AAAGATCACA GGATTCCAGA ATGACATACC GAGAGAGAAG CGAGAGACAC 
GAGATGCAGA TTCTCTCCAA GCCGGAATTC ATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_783609.1
CDS	91..1206
Translation	MPANLTEGSFHANQTVPMLDSSPVACTEIVTFTEALVAEEWGSFYSSFKTEQLITLWVLFVVTIVGNSVVLFSTCRRKRKSRMTFFVTQLAITDSFTGLINILTDIIWRFTGDFMAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQAKVLIGIAWSLSFLFSIPTLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLAIISVIYGLVIRTIWMKSKTHETVISNCSDGKLCCSYNRGLISKAKIKAIKYSIVIILAFICCWSPYFLFDILDNFNVLPDTKERFYASVIIQNLPALNSAINPLIYCIFSSSICSPCKMQRSQDSRMTYRERSERHEMQILSKPEFI

Target ORF information:

RefSeq Version	NM_175678.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus neuropeptide S receptor 1 (Npsr1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175678.3

ORF Insert Sequence:

ATGCCAGCCA ACCTCACAGA GGGCAGCTTT CATGCCAACC AGACTGTGCC GATGCTAGAT 
TCTTCCCCAG TAGCTTGCAC TGAAATTGTG ACGTTCACTG AAGCACTGGT GGCTGAGGAG 
TGGGGCTCCT TCTACTCCTC CTTTAAGACA GAACAGCTGA TAACCCTGTG GGTCCTGTTT 
GTCGTCACTA TTGTGGGAAA CTCTGTTGTG CTGTTCTCCA CGTGCAGAAG AAAAAGAAAG 
TCCAGAATGA CCTTCTTTGT GACACAATTG GCCATCACAG ACTCCTTCAC GGGCCTGATC 
AACATCTTGA CAGACATTAT TTGGCGATTC ACAGGAGACT TCATGGCCCC TGACCTGGTT 
TGCAGAGTCG TCCGCTACTT GCAGGTTGTC CTGCTGTATG CCTCTACCTA CGTCCTGGTG 
TCCCTCAGCA TAGACAGATA CCATGCCATC GTTTACCCCA TGAAGTTTCT TCAAGGAGAG 
AAGCAAGCCA AAGTCCTCAT CGGAATAGCG TGGAGCCTCT CGTTCCTGTT CTCCATTCCC 
ACGCTGATCA TATTTGGGAA AAGGACACTT TCCAATGGTG AGGTGCAGTG CTGGGCACTG 
TGGCCGGATG ACTCCTACTG GACCCCGTAC ATGACCATCG TCGCCTTTCT GGTGTACTTC 
ATTCCCTTGG CAATTATCAG CGTTATCTAT GGCCTTGTGA TCCGAACTAT TTGGATGAAA 
AGCAAAACCC ATGAGACGGT GATTTCCAAC TGCTCAGATG GCAAACTATG CTGCAGCTAC 
AACCGAGGGC TCATCTCTAA GGCAAAAATC AAGGCCATCA AGTATAGCAT CGTCATAATC 
CTTGCTTTCA TCTGCTGCTG GAGCCCATAC TTCCTCTTTG ACATATTAGA CAACTTCAAC 
GTCCTTCCAG ACACCAAGGA GCGTTTCTAT GCCTCTGTGA TTATCCAGAA CCTGCCCGCC 
TTGAACAGTG CCATTAACCC CCTCATCTAC TGCATCTTCA GCAGCTCCAT CTGCTCCCCC 
TGCAAGATGC AAAGATCACA GGATTCCAGA ATGACATACC GAGAGAGAAG CGAGAGACAC 
GAGATGCAGA TTCTCTCCAA GCCGGAATTC ATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Npsr1 ( XM_006510402.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006510465.1 Mus musculus neuropeptide S receptor 1 (Npsr1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu20028
Clone ID Related Accession (Same CDS sequence)	NM_175678.3 , XM_006510402.2 , XM_017313417.1 , XM_017313417.2
Accession Version	XM_006510402.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1116bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-08
Organism	Mus musculus(House mouse)
Product	neuropeptide S receptor isoform X1
Comment

ATGCCAGCCA ACCTCACAGA GGGCAGCTTT CATGCCAACC AGACTGTGCC GATGCTAGAT 
TCTTCCCCAG TAGCTTGCAC TGAAATTGTG ACGTTCACTG AAGCACTGGT GGCTGAGGAG 
TGGGGCTCCT TCTACTCCTC CTTTAAGACA GAACAGCTGA TAACCCTGTG GGTCCTGTTT 
GTCGTCACTA TTGTGGGAAA CTCTGTTGTG CTGTTCTCCA CGTGCAGAAG AAAAAGAAAG 
TCCAGAATGA CCTTCTTTGT GACACAATTG GCCATCACAG ACTCCTTCAC GGGCCTGATC 
AACATCTTGA CAGACATTAT TTGGCGATTC ACAGGAGACT TCATGGCCCC TGACCTGGTT 
TGCAGAGTCG TCCGCTACTT GCAGGTTGTC CTGCTGTATG CCTCTACCTA CGTCCTGGTG 
TCCCTCAGCA TAGACAGATA CCATGCCATC GTTTACCCCA TGAAGTTTCT TCAAGGAGAG 
AAGCAAGCCA AAGTCCTCAT CGGAATAGCG TGGAGCCTCT CGTTCCTGTT CTCCATTCCC 
ACGCTGATCA TATTTGGGAA AAGGACACTT TCCAATGGTG AGGTGCAGTG CTGGGCACTG 
TGGCCGGATG ACTCCTACTG GACCCCGTAC ATGACCATCG TCGCCTTTCT GGTGTACTTC 
ATTCCCTTGG CAATTATCAG CGTTATCTAT GGCCTTGTGA TCCGAACTAT TTGGATGAAA 
AGCAAAACCC ATGAGACGGT GATTTCCAAC TGCTCAGATG GCAAACTATG CTGCAGCTAC 
AACCGAGGGC TCATCTCTAA GGCAAAAATC AAGGCCATCA AGTATAGCAT CGTCATAATC 
CTTGCTTTCA TCTGCTGCTG GAGCCCATAC TTCCTCTTTG ACATATTAGA CAACTTCAAC 
GTCCTTCCAG ACACCAAGGA GCGTTTCTAT GCCTCTGTGA TTATCCAGAA CCTGCCCGCC 
TTGAACAGTG CCATTAACCC CCTCATCTAC TGCATCTTCA GCAGCTCCAT CTGCTCCCCC 
TGCAAGATGC AAAGATCACA GGATTCCAGA ATGACATACC GAGAGAGAAG CGAGAGACAC 
GAGATGCAGA TTCTCTCCAA GCCGGAATTC ATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006510465.1
Translation	MPANLTEGSFHANQTVPMLDSSPVACTEIVTFTEALVAEEWGSFYSSFKTEQLITLWVLFVVTIVGNSVVLFSTCRRKRKSRMTFFVTQLAITDSFTGLINILTDIIWRFTGDFMAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQAKVLIGIAWSLSFLFSIPTLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLAIISVIYGLVIRTIWMKSKTHETVISNCSDGKLCCSYNRGLISKAKIKAIKYSIVIILAFICCWSPYFLFDILDNFNVLPDTKERFYASVIIQNLPALNSAINPLIYCIFSSSICSPCKMQRSQDSRMTYRERSERHEMQILSKPEFI

Target ORF information:

RefSeq Version	XM_006510402.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus neuropeptide S receptor 1 (Npsr1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006510402.2

ORF Insert Sequence:

ATGCCAGCCA ACCTCACAGA GGGCAGCTTT CATGCCAACC AGACTGTGCC GATGCTAGAT 
TCTTCCCCAG TAGCTTGCAC TGAAATTGTG ACGTTCACTG AAGCACTGGT GGCTGAGGAG 
TGGGGCTCCT TCTACTCCTC CTTTAAGACA GAACAGCTGA TAACCCTGTG GGTCCTGTTT 
GTCGTCACTA TTGTGGGAAA CTCTGTTGTG CTGTTCTCCA CGTGCAGAAG AAAAAGAAAG 
TCCAGAATGA CCTTCTTTGT GACACAATTG GCCATCACAG ACTCCTTCAC GGGCCTGATC 
AACATCTTGA CAGACATTAT TTGGCGATTC ACAGGAGACT TCATGGCCCC TGACCTGGTT 
TGCAGAGTCG TCCGCTACTT GCAGGTTGTC CTGCTGTATG CCTCTACCTA CGTCCTGGTG 
TCCCTCAGCA TAGACAGATA CCATGCCATC GTTTACCCCA TGAAGTTTCT TCAAGGAGAG 
AAGCAAGCCA AAGTCCTCAT CGGAATAGCG TGGAGCCTCT CGTTCCTGTT CTCCATTCCC 
ACGCTGATCA TATTTGGGAA AAGGACACTT TCCAATGGTG AGGTGCAGTG CTGGGCACTG 
TGGCCGGATG ACTCCTACTG GACCCCGTAC ATGACCATCG TCGCCTTTCT GGTGTACTTC 
ATTCCCTTGG CAATTATCAG CGTTATCTAT GGCCTTGTGA TCCGAACTAT TTGGATGAAA 
AGCAAAACCC ATGAGACGGT GATTTCCAAC TGCTCAGATG GCAAACTATG CTGCAGCTAC 
AACCGAGGGC TCATCTCTAA GGCAAAAATC AAGGCCATCA AGTATAGCAT CGTCATAATC 
CTTGCTTTCA TCTGCTGCTG GAGCCCATAC TTCCTCTTTG ACATATTAGA CAACTTCAAC 
GTCCTTCCAG ACACCAAGGA GCGTTTCTAT GCCTCTGTGA TTATCCAGAA CCTGCCCGCC 
TTGAACAGTG CCATTAACCC CCTCATCTAC TGCATCTTCA GCAGCTCCAT CTGCTCCCCC 
TGCAAGATGC AAAGATCACA GGATTCCAGA ATGACATACC GAGAGAGAAG CGAGAGACAC 
GAGATGCAGA TTCTCTCCAA GCCGGAATTC ATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Npsr1 ( XM_017313417.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017168906.1 Mus musculus neuropeptide S receptor 1 (Npsr1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu20028
Clone ID Related Accession (Same CDS sequence)	NM_175678.3 , XM_006510402.2 , XM_017313417.1 , XM_017313417.2
Accession Version	XM_017313417.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1116bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	neuropeptide S receptor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAGCCA ACCTCACAGA GGGCAGCTTT CATGCCAACC AGACTGTGCC GATGCTAGAT 
TCTTCCCCAG TAGCTTGCAC TGAAATTGTG ACGTTCACTG AAGCACTGGT GGCTGAGGAG 
TGGGGCTCCT TCTACTCCTC CTTTAAGACA GAACAGCTGA TAACCCTGTG GGTCCTGTTT 
GTCGTCACTA TTGTGGGAAA CTCTGTTGTG CTGTTCTCCA CGTGCAGAAG AAAAAGAAAG 
TCCAGAATGA CCTTCTTTGT GACACAATTG GCCATCACAG ACTCCTTCAC GGGCCTGATC 
AACATCTTGA CAGACATTAT TTGGCGATTC ACAGGAGACT TCATGGCCCC TGACCTGGTT 
TGCAGAGTCG TCCGCTACTT GCAGGTTGTC CTGCTGTATG CCTCTACCTA CGTCCTGGTG 
TCCCTCAGCA TAGACAGATA CCATGCCATC GTTTACCCCA TGAAGTTTCT TCAAGGAGAG 
AAGCAAGCCA AAGTCCTCAT CGGAATAGCG TGGAGCCTCT CGTTCCTGTT CTCCATTCCC 
ACGCTGATCA TATTTGGGAA AAGGACACTT TCCAATGGTG AGGTGCAGTG CTGGGCACTG 
TGGCCGGATG ACTCCTACTG GACCCCGTAC ATGACCATCG TCGCCTTTCT GGTGTACTTC 
ATTCCCTTGG CAATTATCAG CGTTATCTAT GGCCTTGTGA TCCGAACTAT TTGGATGAAA 
AGCAAAACCC ATGAGACGGT GATTTCCAAC TGCTCAGATG GCAAACTATG CTGCAGCTAC 
AACCGAGGGC TCATCTCTAA GGCAAAAATC AAGGCCATCA AGTATAGCAT CGTCATAATC 
CTTGCTTTCA TCTGCTGCTG GAGCCCATAC TTCCTCTTTG ACATATTAGA CAACTTCAAC 
GTCCTTCCAG ACACCAAGGA GCGTTTCTAT GCCTCTGTGA TTATCCAGAA CCTGCCCGCC 
TTGAACAGTG CCATTAACCC CCTCATCTAC TGCATCTTCA GCAGCTCCAT CTGCTCCCCC 
TGCAAGATGC AAAGATCACA GGATTCCAGA ATGACATACC GAGAGAGAAG CGAGAGACAC 
GAGATGCAGA TTCTCTCCAA GCCGGAATTC ATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017168906.1
CDS	251..1366
Translation	MPANLTEGSFHANQTVPMLDSSPVACTEIVTFTEALVAEEWGSFYSSFKTEQLITLWVLFVVTIVGNSVVLFSTCRRKRKSRMTFFVTQLAITDSFTGLINILTDIIWRFTGDFMAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQAKVLIGIAWSLSFLFSIPTLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLAIISVIYGLVIRTIWMKSKTHETVISNCSDGKLCCSYNRGLISKAKIKAIKYSIVIILAFICCWSPYFLFDILDNFNVLPDTKERFYASVIIQNLPALNSAINPLIYCIFSSSICSPCKMQRSQDSRMTYRERSERHEMQILSKPEFI

Target ORF information:

RefSeq Version	XM_017313417.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus neuropeptide S receptor 1 (Npsr1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017313417.1

ORF Insert Sequence:

ATGCCAGCCA ACCTCACAGA GGGCAGCTTT CATGCCAACC AGACTGTGCC GATGCTAGAT 
TCTTCCCCAG TAGCTTGCAC TGAAATTGTG ACGTTCACTG AAGCACTGGT GGCTGAGGAG 
TGGGGCTCCT TCTACTCCTC CTTTAAGACA GAACAGCTGA TAACCCTGTG GGTCCTGTTT 
GTCGTCACTA TTGTGGGAAA CTCTGTTGTG CTGTTCTCCA CGTGCAGAAG AAAAAGAAAG 
TCCAGAATGA CCTTCTTTGT GACACAATTG GCCATCACAG ACTCCTTCAC GGGCCTGATC 
AACATCTTGA CAGACATTAT TTGGCGATTC ACAGGAGACT TCATGGCCCC TGACCTGGTT 
TGCAGAGTCG TCCGCTACTT GCAGGTTGTC CTGCTGTATG CCTCTACCTA CGTCCTGGTG 
TCCCTCAGCA TAGACAGATA CCATGCCATC GTTTACCCCA TGAAGTTTCT TCAAGGAGAG 
AAGCAAGCCA AAGTCCTCAT CGGAATAGCG TGGAGCCTCT CGTTCCTGTT CTCCATTCCC 
ACGCTGATCA TATTTGGGAA AAGGACACTT TCCAATGGTG AGGTGCAGTG CTGGGCACTG 
TGGCCGGATG ACTCCTACTG GACCCCGTAC ATGACCATCG TCGCCTTTCT GGTGTACTTC 
ATTCCCTTGG CAATTATCAG CGTTATCTAT GGCCTTGTGA TCCGAACTAT TTGGATGAAA 
AGCAAAACCC ATGAGACGGT GATTTCCAAC TGCTCAGATG GCAAACTATG CTGCAGCTAC 
AACCGAGGGC TCATCTCTAA GGCAAAAATC AAGGCCATCA AGTATAGCAT CGTCATAATC 
CTTGCTTTCA TCTGCTGCTG GAGCCCATAC TTCCTCTTTG ACATATTAGA CAACTTCAAC 
GTCCTTCCAG ACACCAAGGA GCGTTTCTAT GCCTCTGTGA TTATCCAGAA CCTGCCCGCC 
TTGAACAGTG CCATTAACCC CCTCATCTAC TGCATCTTCA GCAGCTCCAT CTGCTCCCCC 
TGCAAGATGC AAAGATCACA GGATTCCAGA ATGACATACC GAGAGAGAAG CGAGAGACAC 
GAGATGCAGA TTCTCTCCAA GCCGGAATTC ATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Npsr1 ( XM_017313417.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017168906.1 Mus musculus neuropeptide S receptor 1 (Npsr1), transcript variant X1, mRNA.

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CloneID	OMu20028
Clone ID Related Accession (Same CDS sequence)	NM_175678.3 , XM_006510402.2 , XM_017313417.1 , XM_017313417.2
Accession Version	XM_017313417.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1116bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	neuropeptide S receptor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_017313417.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAGCCA ACCTCACAGA GGGCAGCTTT CATGCCAACC AGACTGTGCC GATGCTAGAT 
TCTTCCCCAG TAGCTTGCAC TGAAATTGTG ACGTTCACTG AAGCACTGGT GGCTGAGGAG 
TGGGGCTCCT TCTACTCCTC CTTTAAGACA GAACAGCTGA TAACCCTGTG GGTCCTGTTT 
GTCGTCACTA TTGTGGGAAA CTCTGTTGTG CTGTTCTCCA CGTGCAGAAG AAAAAGAAAG 
TCCAGAATGA CCTTCTTTGT GACACAATTG GCCATCACAG ACTCCTTCAC GGGCCTGATC 
AACATCTTGA CAGACATTAT TTGGCGATTC ACAGGAGACT TCATGGCCCC TGACCTGGTT 
TGCAGAGTCG TCCGCTACTT GCAGGTTGTC CTGCTGTATG CCTCTACCTA CGTCCTGGTG 
TCCCTCAGCA TAGACAGATA CCATGCCATC GTTTACCCCA TGAAGTTTCT TCAAGGAGAG 
AAGCAAGCCA AAGTCCTCAT CGGAATAGCG TGGAGCCTCT CGTTCCTGTT CTCCATTCCC 
ACGCTGATCA TATTTGGGAA AAGGACACTT TCCAATGGTG AGGTGCAGTG CTGGGCACTG 
TGGCCGGATG ACTCCTACTG GACCCCGTAC ATGACCATCG TCGCCTTTCT GGTGTACTTC 
ATTCCCTTGG CAATTATCAG CGTTATCTAT GGCCTTGTGA TCCGAACTAT TTGGATGAAA 
AGCAAAACCC ATGAGACGGT GATTTCCAAC TGCTCAGATG GCAAACTATG CTGCAGCTAC 
AACCGAGGGC TCATCTCTAA GGCAAAAATC AAGGCCATCA AGTATAGCAT CGTCATAATC 
CTTGCTTTCA TCTGCTGCTG GAGCCCATAC TTCCTCTTTG ACATATTAGA CAACTTCAAC 
GTCCTTCCAG ACACCAAGGA GCGTTTCTAT GCCTCTGTGA TTATCCAGAA CCTGCCCGCC 
TTGAACAGTG CCATTAACCC CCTCATCTAC TGCATCTTCA GCAGCTCCAT CTGCTCCCCC 
TGCAAGATGC AAAGATCACA GGATTCCAGA ATGACATACC GAGAGAGAAG CGAGAGACAC 
GAGATGCAGA TTCTCTCCAA GCCGGAATTC ATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017168906.1
CDS	289..1404
Translation	MPANLTEGSFHANQTVPMLDSSPVACTEIVTFTEALVAEEWGSFYSSFKTEQLITLWVLFVVTIVGNSVVLFSTCRRKRKSRMTFFVTQLAITDSFTGLINILTDIIWRFTGDFMAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQAKVLIGIAWSLSFLFSIPTLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLAIISVIYGLVIRTIWMKSKTHETVISNCSDGKLCCSYNRGLISKAKIKAIKYSIVIILAFICCWSPYFLFDILDNFNVLPDTKERFYASVIIQNLPALNSAINPLIYCIFSSSICSPCKMQRSQDSRMTYRERSERHEMQILSKPEFI

Target ORF information:

RefSeq Version	XM_017313417.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus neuropeptide S receptor 1 (Npsr1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017313417.2

ORF Insert Sequence:

ATGCCAGCCA ACCTCACAGA GGGCAGCTTT CATGCCAACC AGACTGTGCC GATGCTAGAT 
TCTTCCCCAG TAGCTTGCAC TGAAATTGTG ACGTTCACTG AAGCACTGGT GGCTGAGGAG 
TGGGGCTCCT TCTACTCCTC CTTTAAGACA GAACAGCTGA TAACCCTGTG GGTCCTGTTT 
GTCGTCACTA TTGTGGGAAA CTCTGTTGTG CTGTTCTCCA CGTGCAGAAG AAAAAGAAAG 
TCCAGAATGA CCTTCTTTGT GACACAATTG GCCATCACAG ACTCCTTCAC GGGCCTGATC 
AACATCTTGA CAGACATTAT TTGGCGATTC ACAGGAGACT TCATGGCCCC TGACCTGGTT 
TGCAGAGTCG TCCGCTACTT GCAGGTTGTC CTGCTGTATG CCTCTACCTA CGTCCTGGTG 
TCCCTCAGCA TAGACAGATA CCATGCCATC GTTTACCCCA TGAAGTTTCT TCAAGGAGAG 
AAGCAAGCCA AAGTCCTCAT CGGAATAGCG TGGAGCCTCT CGTTCCTGTT CTCCATTCCC 
ACGCTGATCA TATTTGGGAA AAGGACACTT TCCAATGGTG AGGTGCAGTG CTGGGCACTG 
TGGCCGGATG ACTCCTACTG GACCCCGTAC ATGACCATCG TCGCCTTTCT GGTGTACTTC 
ATTCCCTTGG CAATTATCAG CGTTATCTAT GGCCTTGTGA TCCGAACTAT TTGGATGAAA 
AGCAAAACCC ATGAGACGGT GATTTCCAAC TGCTCAGATG GCAAACTATG CTGCAGCTAC 
AACCGAGGGC TCATCTCTAA GGCAAAAATC AAGGCCATCA AGTATAGCAT CGTCATAATC 
CTTGCTTTCA TCTGCTGCTG GAGCCCATAC TTCCTCTTTG ACATATTAGA CAACTTCAAC 
GTCCTTCCAG ACACCAAGGA GCGTTTCTAT GCCTCTGTGA TTATCCAGAA CCTGCCCGCC 
TTGAACAGTG CCATTAACCC CCTCATCTAC TGCATCTTCA GCAGCTCCAT CTGCTCCCCC 
TGCAAGATGC AAAGATCACA GGATTCCAGA ATGACATACC GAGAGAGAAG CGAGAGACAC 
GAGATGCAGA TTCTCTCCAA GCCGGAATTC ATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Neuropeptide S ameliorates olfactory spatial memory impairment induced by scopolamine and MK801 through activation of cognate receptor-expressing neurons in the subiculum complex.
Brain structure & function221(6)3327-36(2016 07)
Shao YF,Wang C,Xie JF,Kong XP,Xin L,Dong CY,Li J,Ren WT,Hou YP

Neuropeptide S reduces mouse aggressiveness in the resident/intruder test through selective activation of the neuropeptide S receptor.
Neuropharmacology971-6(2015 Oct)
Ruzza C,Asth L,Guerrini R,Trapella C,Gavioli EC

Selective breeding for high anxiety introduces a synonymous SNP that increases neuropeptide S receptor activity.
The Journal of neuroscience : the official journal of the Society for Neuroscience35(11)4599-613(2015 Mar)
Slattery DA,Naik RR,Grund T,Yen YC,Sartori SB,F?chsl A,Finger BC,Elfving B,Nordemann U,Guerrini R,Calo G,Wegener G,Math? AA,Singewald N,Czibere L,Landgraf R,Neumann ID

Paradoxical response to the sedative effects of diazepam and alcohol in C57BL/6J mice lacking the neuropeptide S receptor.
Peptides61107-13(2014 Nov)
Ghazal P,Corsi M,Roth A,Faggioni F,Corti C,Merlo Pick E,Pucciarelli S,Ciccocioppo R,Ubaldi M

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Neuron83(2)309-323(2014 Jul)
Thompson CL,Ng L,Menon V,Martinez S,Lee CK,Glattfelder K,Sunkin SM,Henry A,Lau C,Dang C,Garcia-Lopez R,Martinez-Ferre A,Pombero A,Rubenstein JLR,Wakeman WB,Hohmann J,Dee N,Sodt AJ,Young R,Smith K,Nguyen TN,Kidney J,Kuan L,Jeromin A,Kaykas A,Miller J,Page D,Orta G,Bernard A,Riley Z,Smith S,Wohnoutka P,Hawrylycz MJ,Puelles L,Jones AR

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Npsr1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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