Ing1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ing1
Entrez Gene ID	26356
Full Name	inhibitor of growth family, member 1
Synonyms	2610028J21Rik,AA407184,AI875420,mING1h,p33Ing1,p37Ing1b
General protein information	Preferred Names inhibitor of growth family, member 1 Names inhibitor of growth protein 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8\|8 A1.1

mRNA and Protein(s)

mRNA	Protein	Name
NM_001302460.1	NP_001289389.1	inhibitor of growth protein 1 isoform 3
NM_001302451.1	NP_001289380.1	inhibitor of growth protein 1 isoform 2
NM_011919.5	NP_036049.2	inhibitor of growth protein 1 isoform 1
NM_001302458.1	NP_001289387.1	inhibitor of growth protein 1 isoform 3
NM_001302459.1	NP_001289388.1	inhibitor of growth protein 1 isoform 3
NM_001302457.1	NP_001289386.1	inhibitor of growth protein 1 isoform 3

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Ing1	NP_036049.2
Rattus norvegicus (Norway rat)	Ing1	NP_001033680.1
Gallus gallus (chicken)	ING1	XP_416956.4
Pan troglodytes (chimpanzee)	ING1	XP_001139907.1
Danio rerio (zebrafish)	ing1	NP_001035446.1
Canis lupus familiaris (dog)	ING1	XP_534185.1
Bos taurus (cattle)	ING1	NP_001071382.1
Xenopus tropicalis (tropical clawed frog)	ing1	NP_001090790.1
Homo sapiens (human)	ING1	NP_937862.1
	ING1	XP_001084274.1
Canis lupus familiaris (dog)	LOC478381	XP_005638810.1
Drosophila melanogaster (fruit fly)	CG7379	NP_650656.1

Gene Ontology
Bibliography

Related articles in PubMed

A Functional Role for the Epigenetic Regulator ING1 in Activity-induced Gene Expression in Primary Cortical Neurons.
Leighton LJ, Zhao Q, Li X, Dai C, Marshall PR, Liu S, Wang Y, Zajaczkowski EL, Khandelwal N, Kumar A, Bredy TW, Wei W
Neuroscience369248-260(2018 Jan)

A novel crosstalk between the tumor suppressors ING1 and ING2 regulates androgen receptor signaling.
Esmaeili M, Pungsrinont T, Schaefer A, Baniahmad A
Journal of molecular medicine (Berlin, Germany)94(10)1167-1179(2016 Oct)

Inhibitors of Growth 1b Suppresses Peroxisome Proliferator-Activated Receptor-?/? Expression Through Downregulation of Hypoxia-Inducible Factor 1? in Osteoblast Differentiation.
Qu B, Hong Z, Gong K, Sheng J, Wu HH, Deng SL, Huang G, Ma ZH, Pan XM
DNA and cell biology35(4)184-91(2016 Apr)

Increased melanoma formation and dissemination in TyrNRas mice deficient in the tumor suppressor Ing1.
Men?ndez C, Adrados I, Fern?ndez-Barral A, Jim?nez B, Flores JM, Ca?amero M, Fuchtbauer EM, Beermann F, Palmero I
Pigment cell & melanoma research27(4)674-7(2014 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Taken together, our findings provide evidence for a novel crosstalk and a crossregulation between ING1 and ING2 in regulating androgen receptor-mediated transactivation and suggest that ING2 acts as a novel corepressor that inhibits AR signaling, prostate cancer cell growth, and migration.
Title: A novel crosstalk between the tumor suppressors ING1 and ING2 regulates androgen receptor signaling.

ING1b is an important regulator of osteoblast differentiation and suppresses PPAR-beta/delta.
Title: Inhibitors of Growth 1b Suppresses Peroxisome Proliferator-Activated Receptor-?/? Expression Through Downregulation of Hypoxia-Inducible Factor 1? in Osteoblast Differentiation.

Increased melanoma formation and dissemination in TyrNRas mice deficient in the tumor suppressor Ing1.
Title: Increased melanoma formation and dissemination in TyrNRas mice deficient in the tumor suppressor Ing1.

Study reveals a novel connection between ING1 and a regulator of microRNA biogenesis and identifies new links between tumor suppressor proteins and the microRNA machinery.
Title: Regulation of the microRNA processor DGCR8 by the tumor suppressor ING1.

A more sophisticated approach, using neural networks, permits prediction of interaction among three or more genes (p53, bax, and ING1).
Title: Nonlinear cooperation of p53-ING1-induced bax expression and protein S-nitrosylation in GSNO-induced thymocyte apoptosis: a quantitative approach with cross-platform validation.

The following Ing1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ing1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu09160	NM_011919.5 Latest version!	Mus musculus inhibitor of growth family, member 1 (Ing1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu69192	NM_001302451.1 Latest version!	Mus musculus inhibitor of growth family, member 1 (Ing1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu69193	NM_001302459.1 Latest version!	Mus musculus inhibitor of growth family, member 1 (Ing1), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu69193	NM_001302457.1 Latest version!	Mus musculus inhibitor of growth family, member 1 (Ing1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu69193	NM_001302458.1 Latest version!	Mus musculus inhibitor of growth family, member 1 (Ing1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu69193	NM_001302460.1 Latest version!	Mus musculus inhibitor of growth family, member 1 (Ing1), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ing1 ( NM_011919.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_036049.2 Mus musculus inhibitor of growth family, member 1 (Ing1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu09160
Clone ID Related Accession (Same CDS sequence)	NM_011919.5
Accession Version	NM_011919.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 840bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-10
Organism	Mus musculus(house mouse)
Product	inhibitor of growth protein 1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC124475.3, CA320790.1, AA407185.1, AK076482.1 and BX528243.1. On Oct 22, 2014 this sequence version replaced NM_011919.4. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BQ895247.1, SRR1660817.221580.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTGAGTC CTGCCAACGG GGAGCAGATC CACCTGGTGA ACTATGTGGA GGATTACCTG 
GACTCAATCG AGTCACTGCC TTTCGACCTG CAGAGGAACG TCTCGCTGAT GCGGGAGATC 
GACGCCAAAT ACCAAGAGAT CCTGAAGGAG CTGGACGACT ACTATGAGAA GTTCAAACGG 
GAGACAGACG GCACCCAGAA GCGCCGGGTA CTGCACTGCA TCCAGAGGGC CCTGATCCGC 
AGCCAGGAGC TAGGCGATGA GAAGATCCAG ATCGTGAGTC AGATGGTGGA GCTGGTGGAG 
AACCGCAGCA GACAGGTGGA CAGTCACGTG GAGCTCTTCG AAGCACACCA GGACATCAGT 
GACGGCACTG GTGGCAGCGG CAAGGCGGGC CAGGACAAGT CGAAGAGTGA GGCCATCACA 
CAGGCAGATA AGCCGAATAA CAAGCGGTCC AGGAGGCAGC GAAACAATGA GAATCGAGAG 
AACGCGTCGA ATAATCACGA CCATGATGAC ATCACCTCAG GAACGCCCAA GGAGAAGAAA 
GCAAAAACCT CAAAGAAGAA GAAACGCTCC AAGGCCAAAG CAGAGAGGGA AGCGTCTCCT 
GCCGACCTTC CCATCGACCC CAACGAGCCC ACGTACTGTC TGTGCAACCA GGTCTCCTAC 
GGGGAGATGA TCGGCTGTGA CAACGACGAA TGCCCCATCG AGTGGTTCCA CTTCTCCTGC 
GTGGGGCTCA ACCATAAACC AAAGGGCAAG TGGTACTGCC CCAAGTGCCG TGGGGAGAGC 
GAGAAGACCA TGGACAAAGC CCTGGAGAAG TCCAAGAAAG AGAGGGCTTA CAACAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036049.2
CDS	454..1293
Translation	MLSPANGEQIHLVNYVEDYLDSIESLPFDLQRNVSLMREIDAKYQEILKELDDYYEKFKRETDGTQKRRVLHCIQRALIRSQELGDEKIQIVSQMVELVENRSRQVDSHVELFEAHQDISDGTGGSGKAGQDKSKSEAITQADKPNNKRSRRQRNNENRENASNNHDHDDITSGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGESEKTMDKALEKSKKERAYNR

Target ORF information:

RefSeq Version	NM_011919.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus inhibitor of growth family, member 1 (Ing1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011919.5

ORF Insert Sequence:

ATGTTGAGTC CTGCCAACGG GGAGCAGATC CACCTGGTGA ACTATGTGGA GGATTACCTG 
GACTCAATCG AGTCACTGCC TTTCGACCTG CAGAGGAACG TCTCGCTGAT GCGGGAGATC 
GACGCCAAAT ACCAAGAGAT CCTGAAGGAG CTGGACGACT ACTATGAGAA GTTCAAACGG 
GAGACAGACG GCACCCAGAA GCGCCGGGTA CTGCACTGCA TCCAGAGGGC CCTGATCCGC 
AGCCAGGAGC TAGGCGATGA GAAGATCCAG ATCGTGAGTC AGATGGTGGA GCTGGTGGAG 
AACCGCAGCA GACAGGTGGA CAGTCACGTG GAGCTCTTCG AAGCACACCA GGACATCAGT 
GACGGCACTG GTGGCAGCGG CAAGGCGGGC CAGGACAAGT CGAAGAGTGA GGCCATCACA 
CAGGCAGATA AGCCGAATAA CAAGCGGTCC AGGAGGCAGC GAAACAATGA GAATCGAGAG 
AACGCGTCGA ATAATCACGA CCATGATGAC ATCACCTCAG GAACGCCCAA GGAGAAGAAA 
GCAAAAACCT CAAAGAAGAA GAAACGCTCC AAGGCCAAAG CAGAGAGGGA AGCGTCTCCT 
GCCGACCTTC CCATCGACCC CAACGAGCCC ACGTACTGTC TGTGCAACCA GGTCTCCTAC 
GGGGAGATGA TCGGCTGTGA CAACGACGAA TGCCCCATCG AGTGGTTCCA CTTCTCCTGC 
GTGGGGCTCA ACCATAAACC AAAGGGCAAG TGGTACTGCC CCAAGTGCCG TGGGGAGAGC 
GAGAAGACCA TGGACAAAGC CCTGGAGAAG TCCAAGAAAG AGAGGGCTTA CAACAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ing1 ( NM_001302451.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001289380.1 Mus musculus inhibitor of growth family, member 1 (Ing1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu69192
Clone ID Related Accession (Same CDS sequence)	NM_001302451.1
Accession Version	NM_001302451.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 732bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-10
Organism	Mus musculus(house mouse)
Product	inhibitor of growth protein 1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ086997.1, AK141466.1, AA407185.1, AK076482.1 and BX528243.1. Transcript Variant: This variant (2) uses an upstream alternate 5' terminal exon and uses an alternate in-frame splice site in the 5' coding region which results in the use of a downstream start codon, compared to variant 1. It encodes isoform 2, which has a shorter N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CJ086997.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164134 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCGGGAGA TCGACGCCAA ATACCAAGAG ATCCTGAAGG AGCTGGACGA CTACTATGAG 
AAGTTCAAAC GGGAGACAGA CGGCACCCAG AAGCGCCGGG TACTGCACTG CATCCAGAGG 
GCCCTGATCC GCAGCCAGGA GCTAGGCGAT GAGAAGATCC AGATCGTGAG TCAGATGGTG 
GAGCTGGTGG AGAACCGCAG CAGACAGGTG GACAGTCACG TGGAGCTCTT CGAAGCACAC 
CAGGACATCA GTGACGGCAC TGGTGGCAGC GGCAAGGCGG GCCAGGACAA GTCGAAGAGT 
GAGGCCATCA CACAGGCAGA TAAGCCGAAT AACAAGCGGT CCAGGAGGCA GCGAAACAAT 
GAGAATCGAG AGAACGCGTC GAATAATCAC GACCATGATG ACATCACCTC AGGAACGCCC 
AAGGAGAAGA AAGCAAAAAC CTCAAAGAAG AAGAAACGCT CCAAGGCCAA AGCAGAGAGG 
GAAGCGTCTC CTGCCGACCT TCCCATCGAC CCCAACGAGC CCACGTACTG TCTGTGCAAC 
CAGGTCTCCT ACGGGGAGAT GATCGGCTGT GACAACGACG AATGCCCCAT CGAGTGGTTC 
CACTTCTCCT GCGTGGGGCT CAACCATAAA CCAAAGGGCA AGTGGTACTG CCCCAAGTGC 
CGTGGGGAGA GCGAGAAGAC CATGGACAAA GCCCTGGAGA AGTCCAAGAA AGAGAGGGCT 
TACAACAGGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001289380.1
CDS	152..883
Translation	MREIDAKYQEILKELDDYYEKFKRETDGTQKRRVLHCIQRALIRSQELGDEKIQIVSQMVELVENRSRQVDSHVELFEAHQDISDGTGGSGKAGQDKSKSEAITQADKPNNKRSRRQRNNENRENASNNHDHDDITSGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGESEKTMDKALEKSKKERAYNR

Target ORF information:

RefSeq Version	NM_001302451.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus inhibitor of growth family, member 1 (Ing1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001302451.1

ORF Insert Sequence:

ATGCGGGAGA TCGACGCCAA ATACCAAGAG ATCCTGAAGG AGCTGGACGA CTACTATGAG 
AAGTTCAAAC GGGAGACAGA CGGCACCCAG AAGCGCCGGG TACTGCACTG CATCCAGAGG 
GCCCTGATCC GCAGCCAGGA GCTAGGCGAT GAGAAGATCC AGATCGTGAG TCAGATGGTG 
GAGCTGGTGG AGAACCGCAG CAGACAGGTG GACAGTCACG TGGAGCTCTT CGAAGCACAC 
CAGGACATCA GTGACGGCAC TGGTGGCAGC GGCAAGGCGG GCCAGGACAA GTCGAAGAGT 
GAGGCCATCA CACAGGCAGA TAAGCCGAAT AACAAGCGGT CCAGGAGGCA GCGAAACAAT 
GAGAATCGAG AGAACGCGTC GAATAATCAC GACCATGATG ACATCACCTC AGGAACGCCC 
AAGGAGAAGA AAGCAAAAAC CTCAAAGAAG AAGAAACGCT CCAAGGCCAA AGCAGAGAGG 
GAAGCGTCTC CTGCCGACCT TCCCATCGAC CCCAACGAGC CCACGTACTG TCTGTGCAAC 
CAGGTCTCCT ACGGGGAGAT GATCGGCTGT GACAACGACG AATGCCCCAT CGAGTGGTTC 
CACTTCTCCT GCGTGGGGCT CAACCATAAA CCAAAGGGCA AGTGGTACTG CCCCAAGTGC 
CGTGGGGAGA GCGAGAAGAC CATGGACAAA GCCCTGGAGA AGTCCAAGAA AGAGAGGGCT 
TACAACAGGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ing1 ( NM_001302460.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001289389.1 Mus musculus inhibitor of growth family, member 1 (Ing1), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OMu69193
Clone ID Related Accession (Same CDS sequence)	NM_001302460.1 , NM_001302458.1 , NM_001302459.1 , NM_001302457.1
Accession Version	NM_001302460.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-10
Organism	Mus musculus(house mouse)
Product	inhibitor of growth protein 1 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ086997.1, AK141466.1, DV655694.1, AK035490.1, AC124475.3 and BX528243.1. Transcript Variant: This variant (6) uses an upstream alternate 5' terminal exon and lacks an exon in the 5' region, which results in the use of a downstream start codon, compared to variant 1. It encodes isoform 3, which has a shorter N-terminus, compared to isoform 1. Variant 3, 4, 5 and 6 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DV655694.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGGAGC TGGTGGAGAA CCGCAGCAGA CAGGTGGACA GTCACGTGGA GCTCTTCGAA 
GCACACCAGG ACATCAGTGA CGGCACTGGT GGCAGCGGCA AGGCGGGCCA GGACAAGTCG 
AAGAGTGAGG CCATCACACA GGCAGATAAG CCGAATAACA AGCGGTCCAG GAGGCAGCGA 
AACAATGAGA ATCGAGAGAA CGCGTCGAAT AATCACGACC ATGATGACAT CACCTCAGGA 
ACGCCCAAGG AGAAGAAAGC AAAAACCTCA AAGAAGAAGA AACGCTCCAA GGCCAAAGCA 
GAGAGGGAAG CGTCTCCTGC CGACCTTCCC ATCGACCCCA ACGAGCCCAC GTACTGTCTG 
TGCAACCAGG TCTCCTACGG GGAGATGATC GGCTGTGACA ACGACGAATG CCCCATCGAG 
TGGTTCCACT TCTCCTGCGT GGGGCTCAAC CATAAACCAA AGGGCAAGTG GTACTGCCCC 
AAGTGCCGTG GGGAGAGCGA GAAGACCATG GACAAAGCCC TGGAGAAGTC CAAGAAAGAG 
AGGGCTTACA ACAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001289389.1
CDS	283..840
Translation	MVELVENRSRQVDSHVELFEAHQDISDGTGGSGKAGQDKSKSEAITQADKPNNKRSRRQRNNENRENASNNHDHDDITSGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGESEKTMDKALEKSKKERAYNR

Target ORF information:

RefSeq Version	NM_001302460.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus inhibitor of growth family, member 1 (Ing1), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001302460.1

ORF Insert Sequence:

ATGGTGGAGC TGGTGGAGAA CCGCAGCAGA CAGGTGGACA GTCACGTGGA GCTCTTCGAA 
GCACACCAGG ACATCAGTGA CGGCACTGGT GGCAGCGGCA AGGCGGGCCA GGACAAGTCG 
AAGAGTGAGG CCATCACACA GGCAGATAAG CCGAATAACA AGCGGTCCAG GAGGCAGCGA 
AACAATGAGA ATCGAGAGAA CGCGTCGAAT AATCACGACC ATGATGACAT CACCTCAGGA 
ACGCCCAAGG AGAAGAAAGC AAAAACCTCA AAGAAGAAGA AACGCTCCAA GGCCAAAGCA 
GAGAGGGAAG CGTCTCCTGC CGACCTTCCC ATCGACCCCA ACGAGCCCAC GTACTGTCTG 
TGCAACCAGG TCTCCTACGG GGAGATGATC GGCTGTGACA ACGACGAATG CCCCATCGAG 
TGGTTCCACT TCTCCTGCGT GGGGCTCAAC CATAAACCAA AGGGCAAGTG GTACTGCCCC 
AAGTGCCGTG GGGAGAGCGA GAAGACCATG GACAAAGCCC TGGAGAAGTC CAAGAAAGAG 
AGGGCTTACA ACAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ing1 ( NM_001302458.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001289387.1 Mus musculus inhibitor of growth family, member 1 (Ing1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OMu69193
Clone ID Related Accession (Same CDS sequence)	NM_001302460.1 , NM_001302458.1 , NM_001302459.1 , NM_001302457.1
Accession Version	NM_001302458.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-10
Organism	Mus musculus(house mouse)
Product	inhibitor of growth protein 1 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC124475.3, CK624100.1, AK076482.1 and BX528243.1. On Oct 22, 2014 this sequence version replaced XM_006508803.1. Transcript Variant: This variant (4) uses an upstream alternate 5' terminal exon and lacks an exon in the 5' region, which results in the use of a downstream start codon, compared to variant 1. It encodes isoform 3, which has a shorter N-terminus, compared to isoform 1. Variant 3, 4, 5 and 6 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF177755.1, SRR1660813.108642.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGGAGC TGGTGGAGAA CCGCAGCAGA CAGGTGGACA GTCACGTGGA GCTCTTCGAA 
GCACACCAGG ACATCAGTGA CGGCACTGGT GGCAGCGGCA AGGCGGGCCA GGACAAGTCG 
AAGAGTGAGG CCATCACACA GGCAGATAAG CCGAATAACA AGCGGTCCAG GAGGCAGCGA 
AACAATGAGA ATCGAGAGAA CGCGTCGAAT AATCACGACC ATGATGACAT CACCTCAGGA 
ACGCCCAAGG AGAAGAAAGC AAAAACCTCA AAGAAGAAGA AACGCTCCAA GGCCAAAGCA 
GAGAGGGAAG CGTCTCCTGC CGACCTTCCC ATCGACCCCA ACGAGCCCAC GTACTGTCTG 
TGCAACCAGG TCTCCTACGG GGAGATGATC GGCTGTGACA ACGACGAATG CCCCATCGAG 
TGGTTCCACT TCTCCTGCGT GGGGCTCAAC CATAAACCAA AGGGCAAGTG GTACTGCCCC 
AAGTGCCGTG GGGAGAGCGA GAAGACCATG GACAAAGCCC TGGAGAAGTC CAAGAAAGAG 
AGGGCTTACA ACAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001289387.1
CDS	364..921
Translation	MVELVENRSRQVDSHVELFEAHQDISDGTGGSGKAGQDKSKSEAITQADKPNNKRSRRQRNNENRENASNNHDHDDITSGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGESEKTMDKALEKSKKERAYNR

Target ORF information:

RefSeq Version	NM_001302458.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus inhibitor of growth family, member 1 (Ing1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001302458.1

ORF Insert Sequence:

ATGGTGGAGC TGGTGGAGAA CCGCAGCAGA CAGGTGGACA GTCACGTGGA GCTCTTCGAA 
GCACACCAGG ACATCAGTGA CGGCACTGGT GGCAGCGGCA AGGCGGGCCA GGACAAGTCG 
AAGAGTGAGG CCATCACACA GGCAGATAAG CCGAATAACA AGCGGTCCAG GAGGCAGCGA 
AACAATGAGA ATCGAGAGAA CGCGTCGAAT AATCACGACC ATGATGACAT CACCTCAGGA 
ACGCCCAAGG AGAAGAAAGC AAAAACCTCA AAGAAGAAGA AACGCTCCAA GGCCAAAGCA 
GAGAGGGAAG CGTCTCCTGC CGACCTTCCC ATCGACCCCA ACGAGCCCAC GTACTGTCTG 
TGCAACCAGG TCTCCTACGG GGAGATGATC GGCTGTGACA ACGACGAATG CCCCATCGAG 
TGGTTCCACT TCTCCTGCGT GGGGCTCAAC CATAAACCAA AGGGCAAGTG GTACTGCCCC 
AAGTGCCGTG GGGAGAGCGA GAAGACCATG GACAAAGCCC TGGAGAAGTC CAAGAAAGAG 
AGGGCTTACA ACAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ing1 ( NM_001302459.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001289388.1 Mus musculus inhibitor of growth family, member 1 (Ing1), transcript variant 5, mRNA.

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CloneID	OMu69193
Clone ID Related Accession (Same CDS sequence)	NM_001302460.1 , NM_001302458.1 , NM_001302459.1 , NM_001302457.1
Accession Version	NM_001302459.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-10
Organism	Mus musculus(house mouse)
Product	inhibitor of growth protein 1 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY063246.1, AK035490.1, AC124475.3 and BX528243.1. On Oct 22, 2014 this sequence version replaced XM_006508802.1. Transcript Variant: This variant (5) uses a downstream alternate 5' terminal exon, which results in the use of a downstream start codon, compared to variant 1. It encodes isoform 3, which has a shorter N-terminus, compared to isoform 1. Variant 3, 4, 5 and 6 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK035490.1, AK157424.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGGAGC TGGTGGAGAA CCGCAGCAGA CAGGTGGACA GTCACGTGGA GCTCTTCGAA 
GCACACCAGG ACATCAGTGA CGGCACTGGT GGCAGCGGCA AGGCGGGCCA GGACAAGTCG 
AAGAGTGAGG CCATCACACA GGCAGATAAG CCGAATAACA AGCGGTCCAG GAGGCAGCGA 
AACAATGAGA ATCGAGAGAA CGCGTCGAAT AATCACGACC ATGATGACAT CACCTCAGGA 
ACGCCCAAGG AGAAGAAAGC AAAAACCTCA AAGAAGAAGA AACGCTCCAA GGCCAAAGCA 
GAGAGGGAAG CGTCTCCTGC CGACCTTCCC ATCGACCCCA ACGAGCCCAC GTACTGTCTG 
TGCAACCAGG TCTCCTACGG GGAGATGATC GGCTGTGACA ACGACGAATG CCCCATCGAG 
TGGTTCCACT TCTCCTGCGT GGGGCTCAAC CATAAACCAA AGGGCAAGTG GTACTGCCCC 
AAGTGCCGTG GGGAGAGCGA GAAGACCATG GACAAAGCCC TGGAGAAGTC CAAGAAAGAG 
AGGGCTTACA ACAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001289388.1
CDS	304..861
Translation	MVELVENRSRQVDSHVELFEAHQDISDGTGGSGKAGQDKSKSEAITQADKPNNKRSRRQRNNENRENASNNHDHDDITSGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGESEKTMDKALEKSKKERAYNR

Target ORF information:

RefSeq Version	NM_001302459.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus inhibitor of growth family, member 1 (Ing1), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001302459.1

ORF Insert Sequence:

ATGGTGGAGC TGGTGGAGAA CCGCAGCAGA CAGGTGGACA GTCACGTGGA GCTCTTCGAA 
GCACACCAGG ACATCAGTGA CGGCACTGGT GGCAGCGGCA AGGCGGGCCA GGACAAGTCG 
AAGAGTGAGG CCATCACACA GGCAGATAAG CCGAATAACA AGCGGTCCAG GAGGCAGCGA 
AACAATGAGA ATCGAGAGAA CGCGTCGAAT AATCACGACC ATGATGACAT CACCTCAGGA 
ACGCCCAAGG AGAAGAAAGC AAAAACCTCA AAGAAGAAGA AACGCTCCAA GGCCAAAGCA 
GAGAGGGAAG CGTCTCCTGC CGACCTTCCC ATCGACCCCA ACGAGCCCAC GTACTGTCTG 
TGCAACCAGG TCTCCTACGG GGAGATGATC GGCTGTGACA ACGACGAATG CCCCATCGAG 
TGGTTCCACT TCTCCTGCGT GGGGCTCAAC CATAAACCAA AGGGCAAGTG GTACTGCCCC 
AAGTGCCGTG GGGAGAGCGA GAAGACCATG GACAAAGCCC TGGAGAAGTC CAAGAAAGAG 
AGGGCTTACA ACAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ing1 ( NM_001302457.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001289386.1 Mus musculus inhibitor of growth family, member 1 (Ing1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu69193
Clone ID Related Accession (Same CDS sequence)	NM_001302460.1 , NM_001302458.1 , NM_001302459.1 , NM_001302457.1
Accession Version	NM_001302457.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-10
Organism	Mus musculus(house mouse)
Product	inhibitor of growth protein 1 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK145553.1, AK141466.1, AK076482.1 and BX528243.1. On Oct 22, 2014 this sequence version replaced XM_006508804.1. Transcript Variant: This variant (3) uses an upstream alternate 5' terminal exon and lacks an exon in the 5' region, which results in the use of a downstream start codon, compared to variant 1. It encodes isoform 3, which has a shorter N-terminus, compared to isoform 1. Variant 3, 4, 5 and 6 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK145553.1, AK076482.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGGAGC TGGTGGAGAA CCGCAGCAGA CAGGTGGACA GTCACGTGGA GCTCTTCGAA 
GCACACCAGG ACATCAGTGA CGGCACTGGT GGCAGCGGCA AGGCGGGCCA GGACAAGTCG 
AAGAGTGAGG CCATCACACA GGCAGATAAG CCGAATAACA AGCGGTCCAG GAGGCAGCGA 
AACAATGAGA ATCGAGAGAA CGCGTCGAAT AATCACGACC ATGATGACAT CACCTCAGGA 
ACGCCCAAGG AGAAGAAAGC AAAAACCTCA AAGAAGAAGA AACGCTCCAA GGCCAAAGCA 
GAGAGGGAAG CGTCTCCTGC CGACCTTCCC ATCGACCCCA ACGAGCCCAC GTACTGTCTG 
TGCAACCAGG TCTCCTACGG GGAGATGATC GGCTGTGACA ACGACGAATG CCCCATCGAG 
TGGTTCCACT TCTCCTGCGT GGGGCTCAAC CATAAACCAA AGGGCAAGTG GTACTGCCCC 
AAGTGCCGTG GGGAGAGCGA GAAGACCATG GACAAAGCCC TGGAGAAGTC CAAGAAAGAG 
AGGGCTTACA ACAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001289386.1
CDS	180..737
Translation	MVELVENRSRQVDSHVELFEAHQDISDGTGGSGKAGQDKSKSEAITQADKPNNKRSRRQRNNENRENASNNHDHDDITSGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGESEKTMDKALEKSKKERAYNR

Target ORF information:

RefSeq Version	NM_001302457.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus inhibitor of growth family, member 1 (Ing1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001302457.1

ORF Insert Sequence:

ATGGTGGAGC TGGTGGAGAA CCGCAGCAGA CAGGTGGACA GTCACGTGGA GCTCTTCGAA 
GCACACCAGG ACATCAGTGA CGGCACTGGT GGCAGCGGCA AGGCGGGCCA GGACAAGTCG 
AAGAGTGAGG CCATCACACA GGCAGATAAG CCGAATAACA AGCGGTCCAG GAGGCAGCGA 
AACAATGAGA ATCGAGAGAA CGCGTCGAAT AATCACGACC ATGATGACAT CACCTCAGGA 
ACGCCCAAGG AGAAGAAAGC AAAAACCTCA AAGAAGAAGA AACGCTCCAA GGCCAAAGCA 
GAGAGGGAAG CGTCTCCTGC CGACCTTCCC ATCGACCCCA ACGAGCCCAC GTACTGTCTG 
TGCAACCAGG TCTCCTACGG GGAGATGATC GGCTGTGACA ACGACGAATG CCCCATCGAG 
TGGTTCCACT TCTCCTGCGT GGGGCTCAAC CATAAACCAA AGGGCAAGTG GTACTGCCCC 
AAGTGCCGTG GGGAGAGCGA GAAGACCATG GACAAAGCCC TGGAGAAGTC CAAGAAAGAG 
AGGGCTTACA ACAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A Functional Role for the Epigenetic Regulator ING1 in Activity-induced Gene Expression in Primary Cortical Neurons.
Neuroscience369248-260(2018 Jan)
Leighton LJ,Zhao Q,Li X,Dai C,Marshall PR,Liu S,Wang Y,Zajaczkowski EL,Khandelwal N,Kumar A,Bredy TW,Wei W

A novel crosstalk between the tumor suppressors ING1 and ING2 regulates androgen receptor signaling.
Journal of molecular medicine (Berlin, Germany)94(10)1167-1179(2016 Oct)
Esmaeili M,Pungsrinont T,Schaefer A,Baniahmad A

Inhibitors of Growth 1b Suppresses Peroxisome Proliferator-Activated Receptor-?/? Expression Through Downregulation of Hypoxia-Inducible Factor 1? in Osteoblast Differentiation.
DNA and cell biology35(4)184-91(2016 Apr)
Qu B,Hong Z,Gong K,Sheng J,Wu HH,Deng SL,Huang G,Ma ZH,Pan XM

Increased melanoma formation and dissemination in TyrNRas mice deficient in the tumor suppressor Ing1.
Pigment cell & melanoma research27(4)674-7(2014 Jul)
Men?ndez C,Adrados I,Fern?ndez-Barral A,Jim?nez B,Flores JM,Ca?amero M,Fuchtbauer EM,Beermann F,Palmero I

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Ing1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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