Raver2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Raver2
Entrez Gene ID	242570
Full Name	ribonucleoprotein, PTB-binding 2
Synonyms	A430091O22Rik
General protein information	Preferred Names ribonucleoprotein, PTB-binding 2 Names ribonucleoprotein PTB-binding 2 protein raver-2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4\|4 C6

mRNA and Protein(s)

mRNA	Protein	Name
NM_183024.1	NP_898845.1	ribonucleoprotein PTB-binding 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	RAVER2	NP_060681.2
Canis lupus familiaris (dog)	RAVER2	XP_005620389.1
Pan troglodytes (chimpanzee)	RAVER2	XP_524729.3
Bos taurus (cattle)	RAVER2	XP_002686384.3
Mus musculus (house mouse)	Raver2	NP_898845.1
Rattus norvegicus (Norway rat)	Raver2	NP_001178796.1
Gallus gallus (chicken)	RAVER2	XP_422525.4
Danio rerio (zebrafish)	raver2	XP_001338083.4
	RAVER2	XP_001090029.2
Xenopus tropicalis (tropical clawed frog)	raver2	NP_001072850.1

Gene Ontology
Bibliography

Related articles in PubMed

Messenger RNA processing is altered in autosomal dominant leukodystrophy.
Bartoletti-Stella A, Gasparini L, Giacomini C, Corrado P, Terlizzi R, Giorgio E, Magini P, Seri M, Baruzzi A, Parchi P, Brusco A, Cortelli P, Capellari S
Human molecular genetics24(10)2746-56(2015 May)

A conserved peptide motif in Raver2 mediates its interaction with the polypyrimidine tract-binding protein.
Henneberg B, Swiniarski S, Sabine Becke, Illenberger S
Experimental cell research316(6)966-79(2010 Apr)

The hnRNP and cytoskeletal protein raver1 contributes to synaptic plasticity.
Lahmann I, Fabienke M, Henneberg B, Pabst O, Vauti F, Minge D, Illenberger S, Jockusch BM, Korte M, Arnold HH
Experimental cell research314(5)1048-60(2008 Mar)

Raver2, a new member of the hnRNP family.
Kleinhenz B, Fabienke M, Swiniarski S, Wittenmayer N, Kirsch J, Jockusch BM, Arnold HH, Illenberger S
FEBS letters579(20)4254-8(2005 Aug)

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA
BMC developmental biology514(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The conserved mode of polypyrimidine tract-binding protein binding suggests that Raver2, like Raver1, may function as a modulator of PTB activity.
Title: A conserved peptide motif in Raver2 mediates its interaction with the polypyrimidine tract-binding protein.

Raver2 was identified as a novel member of the hnRNP family, it interacts with PTB/hnRNPI.
Title: Raver2, a new member of the hnRNP family.

The following Raver2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Raver2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu18575	NM_183024.1 Latest version!	Mus musculus ribonucleoprotein, PTB-binding 2 (Raver2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Raver2 ( NM_183024.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_898845.1 Mus musculus ribonucleoprotein, PTB-binding 2 (Raver2), mRNA.

Price & Availability↑

CloneID	OMu18575
Clone ID Related Accession (Same CDS sequence)	NM_183024.1
Accession Version	NM_183024.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2022bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Mus musculus(house mouse)
Product	ribonucleoprotein PTB-binding 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC055329.1. ##Evidence-Data-START## Transcript exon combination :: BC055329.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGCGC GGGGAGGCGG CGCGGGGGGC GCGGGCTCGG GATCCGGACC CTCTGCTGGG 
ACGGCGGGGG AGGCCGCGGA GCCCGCGCTG CGCCCGGGGG AGGTGGCTGC GCTGCACCCC 
CAGGAGGTGG CTGCACGGCT GCAGCGGATG CGACGGGAGC TGAGCAACCG GCGGAAAATC 
CTAGTGAAAA ACCTGCCCCA GGACAGCAGC TCCCAGGAGG TTCATGAGTT ATTACAGGAC 
TATGAGCTAA AGTATTGCTA TGTGGACAGG AATAAACGAA CAGCTTTTGT TACCTTATTG 
AATGGGGAGC AGGCGCAGAG CGCGATTCAG AGGTTTCATC AGTTTTCTTT CCGAGGCAGA 
GAGTTGACAG TGCAGCTGCA GCCCACAGAC GCTCTCTTGT GCATCACCAA CCTGCCCATC 
TCCTTCACCT TAGAAGAGTT TGAAGAACTC GTCCGTGCCT ATGGCAACAT CGAGAGATGT 
TTTTTGGTCT ACAGTGAAGT TACTGGCCAC TCCAAAGGCT ACGGGTTTGT GGAGTACATG 
AAGAAGGACT TTGCTGCCAA GGCCAGACTG GAGCTACTGG GCAGGCAGAT GGGAGCCTCG 
GCGCTCTTCG CACAGTGGAT GGATGTTAAT CTCTTGGCCT CGGAGCTCAT CCATTCTAAG 
TGCCTTTGTA TAGATAAACT CCCCAGTGAC TACAGCGATT CGGAAGAGCT CTTGCAACTT 
TTTTCCGGTA TCCATAAACC TGTGTTTTGC CAGCTTGCAC AGGATGAAGG AAGTCACGGT 
GGTGGCTTTG CGGTGGTTGA ATATAGCACT GCGGAGCATG CCGAAGAGGT TCAGCAGGTG 
GCAGATGGCA TCACCATCAA GGGGAGCCAA GTTCAACTGT CCTTCTGCGC CCCAGGAGCA 
CCAGGGCGAA GCACTCTAGC AGTCCTCATA GCAGCTCAGC GCGCGATGCA CAGTAATCAA 
AAGGGATTAC TGCCAGAACC CAATCCGGTA CAGATTATGA AAAGTTTAAA CAACCCTGCC 
ATGTTACAAG TTCTTCTGCA GCCCCAGCTA TGCGGACGAG CCATGAAGCC AGTTCTCGGA 
GTCGCGCCCA GCTTATCTCA CCTGCTGAGT CCGTCACTCC CCTCCGCCAT CTTACACTTC 
AGTAAAGCAC AGCAGAGCTC AGCTGTGGGT AATACATCGT CCTTAATCCT TCAGAACCTG 
TCTCCCTTGC CCTTGATACA GCAACAGTTG ATGAAGTTTG ACAATGCCCA CACTAACAAT 
AAGCCTGGCT TGCTGGGAGA GCCTCCTGCC ATGGTACTGC AGCCTGCTCT GGCGATAGGG 
CCACCGCTTC CACTGAAAAC GGACCTGGGA CACCATGGCG AAGCACACAA AACATCTAAC 
CTGATTCCAC CTCAGACGAC ATTGGCAGCC GGGCTGGGCA TGCTGCCGTT CTTCTCAAAC 
CAGCTCCCTG CTGGACAAGC CGGCCCGGGG CGTGGGACCA CTCAGGAGAA ACAGTCCGCT 
TCGGTGAGCA TTAGCGAAGC TAGCTTCTCA GGGTCGCAGC ATTACCTGCA GACCTTCCCA 
GGCCTTCCTG CTGGAGGCCC GCTGACGGGC AACCAGAAGA CACCGCAGAG CCAGCCAAAA 
GGCACAGAGG TTGCCTCTAA GAATCAGACT TCACTCTTGG GAGAACCACC AAAAGAGATC 
CGGCTCAGTA AAAATCCATA TTTGAATTTG GCAAGTGTGC TACCCAGTGT GTGCCTATCC 
ACTGCAGGTA AAGGCATGCC TCCGAAGACT GGAATTGCGA GCAACATTCT GGATGCGATC 
TCTCAGGGAA GTGAGTCCCA GCATGCACTG GAGAAGTGCA TCGCCTATTC TCCATCCATC 
GAGGATTATG CCCAGGCATC CTCCTTGAGG AATGAGAAGC GAGGCTCCTC CTATCTCATC 
TCTGCCCCAG AAGGAGGCCC GGTAGAACTC GCTGGCCAGC ACCCTCAGGA CACCGGAGTG 
AGCTACACAG AAACCTACTT GAAAAAGAAG CGTGTGTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_898845.1
CDS	77..2098
Translation	MAARGGGAGGAGSGSGPSAGTAGEAAEPALRPGEVAALHPQEVAARLQRMRRELSNRRKILVKNLPQDSSSQEVHELLQDYELKYCYVDRNKRTAFVTLLNGEQAQSAIQRFHQFSFRGRELTVQLQPTDALLCITNLPISFTLEEFEELVRAYGNIERCFLVYSEVTGHSKGYGFVEYMKKDFAAKARLELLGRQMGASALFAQWMDVNLLASELIHSKCLCIDKLPSDYSDSEELLQLFSGIHKPVFCQLAQDEGSHGGGFAVVEYSTAEHAEEVQQVADGITIKGSQVQLSFCAPGAPGRSTLAVLIAAQRAMHSNQKGLLPEPNPVQIMKSLNNPAMLQVLLQPQLCGRAMKPVLGVAPSLSHLLSPSLPSAILHFSKAQQSSAVGNTSSLILQNLSPLPLIQQQLMKFDNAHTNNKPGLLGEPPAMVLQPALAIGPPLPLKTDLGHHGEAHKTSNLIPPQTTLAAGLGMLPFFSNQLPAGQAGPGRGTTQEKQSASVSISEASFSGSQHYLQTFPGLPAGGPLTGNQKTPQSQPKGTEVASKNQTSLLGEPPKEIRLSKNPYLNLASVLPSVCLSTAGKGMPPKTGIASNILDAISQGSESQHALEKCIAYSPSIEDYAQASSLRNEKRGSSYLISAPEGGPVELAGQHPQDTGVSYTETYLKKKRVY

Target ORF information:

RefSeq Version	NM_183024.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ribonucleoprotein, PTB-binding 2 (Raver2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_183024.1

ORF Insert Sequence:

ATGGCGGCGC GGGGAGGCGG CGCGGGGGGC GCGGGCTCGG GATCCGGACC CTCTGCTGGG 
ACGGCGGGGG AGGCCGCGGA GCCCGCGCTG CGCCCGGGGG AGGTGGCTGC GCTGCACCCC 
CAGGAGGTGG CTGCACGGCT GCAGCGGATG CGACGGGAGC TGAGCAACCG GCGGAAAATC 
CTAGTGAAAA ACCTGCCCCA GGACAGCAGC TCCCAGGAGG TTCATGAGTT ATTACAGGAC 
TATGAGCTAA AGTATTGCTA TGTGGACAGG AATAAACGAA CAGCTTTTGT TACCTTATTG 
AATGGGGAGC AGGCGCAGAG CGCGATTCAG AGGTTTCATC AGTTTTCTTT CCGAGGCAGA 
GAGTTGACAG TGCAGCTGCA GCCCACAGAC GCTCTCTTGT GCATCACCAA CCTGCCCATC 
TCCTTCACCT TAGAAGAGTT TGAAGAACTC GTCCGTGCCT ATGGCAACAT CGAGAGATGT 
TTTTTGGTCT ACAGTGAAGT TACTGGCCAC TCCAAAGGCT ACGGGTTTGT GGAGTACATG 
AAGAAGGACT TTGCTGCCAA GGCCAGACTG GAGCTACTGG GCAGGCAGAT GGGAGCCTCG 
GCGCTCTTCG CACAGTGGAT GGATGTTAAT CTCTTGGCCT CGGAGCTCAT CCATTCTAAG 
TGCCTTTGTA TAGATAAACT CCCCAGTGAC TACAGCGATT CGGAAGAGCT CTTGCAACTT 
TTTTCCGGTA TCCATAAACC TGTGTTTTGC CAGCTTGCAC AGGATGAAGG AAGTCACGGT 
GGTGGCTTTG CGGTGGTTGA ATATAGCACT GCGGAGCATG CCGAAGAGGT TCAGCAGGTG 
GCAGATGGCA TCACCATCAA GGGGAGCCAA GTTCAACTGT CCTTCTGCGC CCCAGGAGCA 
CCAGGGCGAA GCACTCTAGC AGTCCTCATA GCAGCTCAGC GCGCGATGCA CAGTAATCAA 
AAGGGATTAC TGCCAGAACC CAATCCGGTA CAGATTATGA AAAGTTTAAA CAACCCTGCC 
ATGTTACAAG TTCTTCTGCA GCCCCAGCTA TGCGGACGAG CCATGAAGCC AGTTCTCGGA 
GTCGCGCCCA GCTTATCTCA CCTGCTGAGT CCGTCACTCC CCTCCGCCAT CTTACACTTC 
AGTAAAGCAC AGCAGAGCTC AGCTGTGGGT AATACATCGT CCTTAATCCT TCAGAACCTG 
TCTCCCTTGC CCTTGATACA GCAACAGTTG ATGAAGTTTG ACAATGCCCA CACTAACAAT 
AAGCCTGGCT TGCTGGGAGA GCCTCCTGCC ATGGTACTGC AGCCTGCTCT GGCGATAGGG 
CCACCGCTTC CACTGAAAAC GGACCTGGGA CACCATGGCG AAGCACACAA AACATCTAAC 
CTGATTCCAC CTCAGACGAC ATTGGCAGCC GGGCTGGGCA TGCTGCCGTT CTTCTCAAAC 
CAGCTCCCTG CTGGACAAGC CGGCCCGGGG CGTGGGACCA CTCAGGAGAA ACAGTCCGCT 
TCGGTGAGCA TTAGCGAAGC TAGCTTCTCA GGGTCGCAGC ATTACCTGCA GACCTTCCCA 
GGCCTTCCTG CTGGAGGCCC GCTGACGGGC AACCAGAAGA CACCGCAGAG CCAGCCAAAA 
GGCACAGAGG TTGCCTCTAA GAATCAGACT TCACTCTTGG GAGAACCACC AAAAGAGATC 
CGGCTCAGTA AAAATCCATA TTTGAATTTG GCAAGTGTGC TACCCAGTGT GTGCCTATCC 
ACTGCAGGTA AAGGCATGCC TCCGAAGACT GGAATTGCGA GCAACATTCT GGATGCGATC 
TCTCAGGGAA GTGAGTCCCA GCATGCACTG GAGAAGTGCA TCGCCTATTC TCCATCCATC 
GAGGATTATG CCCAGGCATC CTCCTTGAGG AATGAGAAGC GAGGCTCCTC CTATCTCATC 
TCTGCCCCAG AAGGAGGCCC GGTAGAACTC GCTGGCCAGC ACCCTCAGGA CACCGGAGTG 
AGCTACACAG AAACCTACTT GAAAAAGAAG CGTGTGTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Messenger RNA processing is altered in autosomal dominant leukodystrophy.
Human molecular genetics24(10)2746-56(2015 May)
Bartoletti-Stella A,Gasparini L,Giacomini C,Corrado P,Terlizzi R,Giorgio E,Magini P,Seri M,Baruzzi A,Parchi P,Brusco A,Cortelli P,Capellari S

A conserved peptide motif in Raver2 mediates its interaction with the polypyrimidine tract-binding protein.
Experimental cell research316(6)966-79(2010 Apr)
Henneberg B,Swiniarski S,Sabine Becke,Illenberger S

The hnRNP and cytoskeletal protein raver1 contributes to synaptic plasticity.
Experimental cell research314(5)1048-60(2008 Mar)
Lahmann I,Fabienke M,Henneberg B,Pabst O,Vauti F,Minge D,Illenberger S,Jockusch BM,Korte M,Arnold HH

Raver2, a new member of the hnRNP family.
FEBS letters579(20)4254-8(2005 Aug)
Kleinhenz B,Fabienke M,Swiniarski S,Wittenmayer N,Kirsch J,Jockusch BM,Arnold HH,Illenberger S

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
BMC developmental biology514(2005 Jul)
McKee AE,Minet E,Stern C,Riahi S,Stiles CD,Silver PA