Adam23 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Adam23
Entrez Gene ID	23792
Full Name	a disintegrin and metallopeptidase domain 23
Synonyms	AW046396,MDC3
General protein information	Preferred Names a disintegrin and metallopeptidase domain 23 Names disintegrin and metalloproteinase domain-containing protein 23 a disintegrin and metalloprotease domain 23 metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1 C2\|1 32.31 cM
Summary	This gene encodes a member of the disintegrin family of membrane-anchored proteins that play a role in diverse biological processes such as brain development, fertilization, tumor development and inflammation. The encoded protein undergoes proteolytic processing to generate a mature polypeptide comprised of an inactive metalloprotease and disintegrin domains. Transgenic disruption of this gene in mice results in postnatal neurological defects including tremor and ataxia resulting in death by 2 weeks of age. [provided by RefSeq, Sep 2015].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006495969.4	XP_006496032.1	disintegrin and metalloproteinase domain-containing protein 23 isoform X1
XM_006495969.3	XP_006496032.1	disintegrin and metalloproteinase domain-containing protein 23 isoform X1
XM_006495970.3	XP_006496033.1	disintegrin and metalloproteinase domain-containing protein 23 isoform X2
XM_006495970.4	XP_006496033.1	disintegrin and metalloproteinase domain-containing protein 23 isoform X2
NM_011780.3	NP_035910.1	disintegrin and metalloproteinase domain-containing protein 23 preproprotein

Pathways from BioSystems

Homologies

Homo sapiens (human)	ADAM23	NP_003803.1
	ADAM23	XP_001106619.2
Bos taurus (cattle)	ADAM23	NP_001076927.1
Rattus norvegicus (Norway rat)	Adam23	NP_001025070.1
Gallus gallus (chicken)	ADAM23	NP_001138702.1
Pan troglodytes (chimpanzee)	ADAM23	XP_516049.3
Mus musculus (house mouse)	Adam23	NP_035910.1
Canis lupus familiaris (dog)	ADAM23	XP_849852.1
Xenopus tropicalis (tropical clawed frog)	adam23	NP_001233135.1
Danio rerio (zebrafish)	wu:fj40f01	XP_005165908.1

Gene Ontology
Bibliography

Related articles in PubMed

Dendritic cell expression of ADAM23 governs T cell proliferation and cytokine production through the ?(v)?(3) integrin receptor.
Elizondo DM, Andargie TE, Marshall KM, Zariwala AM, Lipscomb MW
Journal of leukocyte biology100(5)855-864(2016 11)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes.
Chen N, Koopmans F, Gordon A, Paliukhovich I, Klaassen RV, van der Schors RC, Peles E, Verhage M, Smit AB, Li KW
Biochimica et biophysica acta1854(7)827-33(2015 Jul)

Functional phylogenetic analysis of LGI proteins identifies an interaction motif crucial for myelination.
Kegel L, Jaegle M, Driegen S, Aunin E, Leslie K, Fukata Y, Watanabe M, Fukata M, Meijer D
Development (Cambridge, England)141(8)1749-56(2014 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ADAM23 expression on DCs partially governs antigen-presentation capacities to responder CD4(+) T cells. Knockdown did not alter the maturation profile of DCs but impaired cognate T cell responses, decreased antigen-specific clonal expansion, and decreased Th cytokine production. Targeting the alpha(v)beta(3) integrin receptors resulted in similar phenotypes indicating their role in the ADAM23 response.
Title: Dendritic cell expression of ADAM23 governs T cell proliferation and cytokine production through the ?(v)?(3) integrin receptor.

Interaction proteomics revealed the interactors of Caspr2, including CNTN2, KCNAs, members of the ADAM family (ADAM22, ADAM23 and ADAM11), members of LGI family and MAGUKs (DLGs and MPPs).
Title: Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes.

Data suggest that leucine-rich glioma inactivated 3 (LGI3) may be a candidate adipokine that is perturbed in obesity and suppresses adipogenesis through its receptor, ADAM23.
Title: Leucine-rich glioma inactivated 3 regulates adipogenesis through ADAM23.

Adam23 knockdown up-regulates P27KIP1 in P19/ADAM23 knockdown cells, one reason that P19/ADAM23 knockdown cells can differentiate into neurons without retinoic acid induction.
Title: ADAM23 knockdown promotes neuronal differentiation of P19 embryonal carcinoma cells by up-regulating P27KIP1 expression.

Data suggest that LGI1 binding to ADAM23 is necessary to correctly pattern neuronal morphology, and altered anatomical patterning contributes to autosomal dominant partial epilepsy with auditory features.
Title: LGI1-associated epilepsy through altered ADAM23-dependent neuronal morphology.

The following Adam23 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Adam23 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu27413	XM_006495969.4 Latest version!	Mus musculus a disintegrin and metallopeptidase domain 23 (Adam23), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMu27414	XM_006495970.4 Latest version!	Mus musculus a disintegrin and metallopeptidase domain 23 (Adam23), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMu08823	NM_011780.3 Latest version!	Mus musculus a disintegrin and metallopeptidase domain 23 (Adam23), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$489.30 $699.00
View Old Accession Versions >>
OMu27413	XM_006495969.3	Mus musculus a disintegrin and metallopeptidase domain 23 (Adam23), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
OMu27414	XM_006495970.3	Mus musculus a disintegrin and metallopeptidase domain 23 (Adam23), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Adam23 ( XM_006495969.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006496032.1 Mus musculus a disintegrin and metallopeptidase domain 23 (Adam23), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu27413
Clone ID Related Accession (Same CDS sequence)	XM_006495969.4 , XM_006495969.3
Accession Version	XM_006495969.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2490bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	disintegrin and metalloproteinase domain-containing protein 23 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006495969.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCCGC CCGGCAGCAT CTCCCGGCGG CCGACCCTGA CGGGTTGCAG CCTTCCCGGC 
GCCTCCTGCG GCCCCGGCCG CTGCCCCGCC GGCCCGGTGC CGGCCCGCGC GCCGCCCTGC 
CGCCTGCTCC TCGTCCTTCT CCTGCTACCT GCGCTCGCCA CCTCATCCCG GCCCCGTGCC 
CGGGGGGCCG CTGCGCCCAG CGCTCCGCAC TGGAATGAAA CTGCAGAAAA AACCCTGGGA 
GTCCTGGCAG ATGAAGACAA CACATTGCAA CAAAATAGCA GCAGCAGAAA TACCAGCTAC 
AGCAGTGCAG TGCAAAAAGA AATCACACTG CCTTCAAGAC TGGTGTATTA CATCAACCAG 
GACTCAGAAA GCCCCTATCA TGTTCTTGAC ACAAAGGCCA GACACCAACA GAAACACAAT 
AAGGCTGTGC ATCTGGCCCA GGCAAGCTTC CAGATCGAAG CTTTCGGCTC CAAGTTCATT 
CTTGACCTCA CACTGAACAA TGGTTTGCTA TCTTCTGACT ACGTGGAGAT CCACTATGAA 
GACGGGAAGC AGATGTACTC TAAGGGTGGA GAGCACTGTT ACTACCACGG AAGCATCAGA 
GGCGTCAAGG ATTCCAGGGT GGCTCTATCG ACCTGCAATG GACTCCATGG CATGTTTGAG 
GATGACACCT TTGTGTATAT GATAGAGCCG CTGGAACTGA CTGATGATGA GAAAAGCACA 
GGCCGACCAC ACATAATCCA GAAAACCTTG GCAGGACAGT ATTCTAAGCA GATGAAGAAT 
CTCAGCACAG ATGGCAGTGA CCAGTGGCCT TTGCTACCTG AATTACAATG GCTGAGAAGA 
AGGAAAAGAG CGGTCAATCC ATCTCGTGGT GTGTTTGAAG AAATGAAGTA TTTGGAGCTT 
ATGATTGTTA ATGATCACAA GACGTATAAG AAGCACCGCT CTTCTCACGC GCATACCAAC 
AACTTCGCAA AGTCTGTGGT CAACCTTGTA GATTCTATTT ACAAGGAACA GCTCAACACC 
AGGGTTGTCC TGGTGGCTGT CGAGACCTGG ACCGAGAAGG ATCACATTGA CATCACCATC 
AACCCCGTGC AGATGCTACA TGACTTCTCC AAGTACCGGC AGCGAATCAA ACAGCACGCT 
GACGCGGTCC ACCTCATCTC GCGCGTGACA TTCCATTATA AGAGAAGCAG TCTGAGTTAC 
TTTGGAGGCG TGTGTTCTCG AATAAGAGGG GTTGGTGTGA ATGAGTATGG TCTTCCAATG 
GCGGTGGCAC AAGTATTATC ACAGAGCCTG GCTCAAAACC TTGGAATCCA GTGGGAACCT 
TCGAGCAGGA AGCCAAAATG TGAATGCATA GAGTCCTGGG GCGGCTGCAT CATGGAAGAA 
ACAGGGGTGT CCCACTCTCG AAAGTTCTCA AAGTGCAGCA TTTTGGAGTA CAGAGACTTT 
TTACAGAGAG GTGGCGGAGC ATGTCTTTTC AATAGGCCAA CTAAGCTGTT TGAGCCCACG 
GAATGTGGAA ATGGATATGT GGAGGCCGGG GAGGAATGCG ACTGTGGTTT CCATGTGGAA 
TGCTATGGAG TTTGCTGTAA GAAGTGTTCG CTCTCCAATG GGGCCCACTG CAGTGACGGC 
CCCTGCTGTA ACAACACCTC ATGTCTTTTT CAGTCACGAG GGTATGAATG TCGGGATGCC 
GTAAACAGCT GTGATATCAC CGAGTACTGC ACTGGAGACT CTGGCCAGTG CCCACCGAAC 
CTCCATAAAC AAGATGGCTA TAGCTGCAAT CAAAATCAGG GTCGCTGCTA CAATGGCGAG 
TGCAAGACAA GGGACAATCA ATGCCAGTAC ATCTGGGGGA CAAAGGCTGC GGGGTCAGAC 
AAGTTCTGCT ATGAAAAGCT GAACACGGAA GGCACCGAGA AGGGCAATTG TGGAAAGGAT 
GGAGACCGGT GGATCCCGTG CAGCAAGCAT GATGTGTTCT GTGGATTTCT GCTTTGCACC 
AATCTTACCC GAGCTCCACG TATCGGTCAA CTTCAAGGAG AGATCATCCC GACTTCCTTC 
TATCATCAAG GCCGAGTGAT TGACTGCAGT GGTGCTCATG TAGTTTTAGA CGATGATACA 
GACGTGGGTT ACGTTGAAGA TGGGACTCCG TGTGGCCCCT CCATGATGTG CTTAGATCGG 
AAGTGCCTAC AGATTCAAGC CCTGAATATG AGCAGCTGCC CACTTGACTC AAGGGGTAAA 
GTCTGCTCCG GCCACGGGGT GTGTAGCAAC GAAGCCACCT GCATCTGTGA TTTCACTTGG 
GCAGGCACAG ACTGCAGCAT CCGGGATCCA GTTCGGAACC CCAACCCCCC TAAGGATGAA 
GGCCCTAAGG TGAACATGGC CACGAGCAGG CTCATAGGGG CCGTGGCTGG CACCGTTCTG 
GCCCTGGGGG TGATTTTTGG AGGCACAGGG TGGGGCATAG AAAACGTCAA GAAGAGGAGA 
TTCGATCCCA CTCAGCAAGG CCCCATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006496032.1
CDS	495..2984
Translation	MKPPGSISRRPTLTGCSLPGASCGPGRCPAGPVPARAPPCRLLLVLLLLPALATSSRPRARGAAAPSAPHWNETAEKTLGVLADEDNTLQQNSSSRNTSYSSAVQKEITLPSRLVYYINQDSESPYHVLDTKARHQQKHNKAVHLAQASFQIEAFGSKFILDLTLNNGLLSSDYVEIHYEDGKQMYSKGGEHCYYHGSIRGVKDSRVALSTCNGLHGMFEDDTFVYMIEPLELTDDEKSTGRPHIIQKTLAGQYSKQMKNLSTDGSDQWPLLPELQWLRRRKRAVNPSRGVFEEMKYLELMIVNDHKTYKKHRSSHAHTNNFAKSVVNLVDSIYKEQLNTRVVLVAVETWTEKDHIDITINPVQMLHDFSKYRQRIKQHADAVHLISRVTFHYKRSSLSYFGGVCSRIRGVGVNEYGLPMAVAQVLSQSLAQNLGIQWEPSSRKPKCECIESWGGCIMEETGVSHSRKFSKCSILEYRDFLQRGGGACLFNRPTKLFEPTECGNGYVEAGEECDCGFHVECYGVCCKKCSLSNGAHCSDGPCCNNTSCLFQSRGYECRDAVNSCDITEYCTGDSGQCPPNLHKQDGYSCNQNQGRCYNGECKTRDNQCQYIWGTKAAGSDKFCYEKLNTEGTEKGNCGKDGDRWIPCSKHDVFCGFLLCTNLTRAPRIGQLQGEIIPTSFYHQGRVIDCSGAHVVLDDDTDVGYVEDGTPCGPSMMCLDRKCLQIQALNMSSCPLDSRGKVCSGHGVCSNEATCICDFTWAGTDCSIRDPVRNPNPPKDEGPKVNMATSRLIGAVAGTVLALGVIFGGTGWGIENVKKRRFDPTQQGPI

Target ORF information:

RefSeq Version	XM_006495969.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus a disintegrin and metallopeptidase domain 23 (Adam23), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006495969.4

ORF Insert Sequence:

ATGAAGCCGC CCGGCAGCAT CTCCCGGCGG CCGACCCTGA CGGGTTGCAG CCTTCCCGGC 
GCCTCCTGCG GCCCCGGCCG CTGCCCCGCC GGCCCGGTGC CGGCCCGCGC GCCGCCCTGC 
CGCCTGCTCC TCGTCCTTCT CCTGCTACCT GCGCTCGCCA CCTCATCCCG GCCCCGTGCC 
CGGGGGGCCG CTGCGCCCAG CGCTCCGCAC TGGAATGAAA CTGCAGAAAA AACCCTGGGA 
GTCCTGGCAG ATGAAGACAA CACATTGCAA CAAAATAGCA GCAGCAGAAA TACCAGCTAC 
AGCAGTGCAG TGCAAAAAGA AATCACACTG CCTTCAAGAC TGGTGTATTA CATCAACCAG 
GACTCAGAAA GCCCCTATCA TGTTCTTGAC ACAAAGGCCA GACACCAACA GAAACACAAT 
AAGGCTGTGC ATCTGGCCCA GGCAAGCTTC CAGATCGAAG CTTTCGGCTC CAAGTTCATT 
CTTGACCTCA CACTGAACAA TGGTTTGCTA TCTTCTGACT ACGTGGAGAT CCACTATGAA 
GACGGGAAGC AGATGTACTC TAAGGGTGGA GAGCACTGTT ACTACCACGG AAGCATCAGA 
GGCGTCAAGG ATTCCAGGGT GGCTCTATCG ACCTGCAATG GACTCCATGG CATGTTTGAG 
GATGACACCT TTGTGTATAT GATAGAGCCG CTGGAACTGA CTGATGATGA GAAAAGCACA 
GGCCGACCAC ACATAATCCA GAAAACCTTG GCAGGACAGT ATTCTAAGCA GATGAAGAAT 
CTCAGCACAG ATGGCAGTGA CCAGTGGCCT TTGCTACCTG AATTACAATG GCTGAGAAGA 
AGGAAAAGAG CGGTCAATCC ATCTCGTGGT GTGTTTGAAG AAATGAAGTA TTTGGAGCTT 
ATGATTGTTA ATGATCACAA GACGTATAAG AAGCACCGCT CTTCTCACGC GCATACCAAC 
AACTTCGCAA AGTCTGTGGT CAACCTTGTA GATTCTATTT ACAAGGAACA GCTCAACACC 
AGGGTTGTCC TGGTGGCTGT CGAGACCTGG ACCGAGAAGG ATCACATTGA CATCACCATC 
AACCCCGTGC AGATGCTACA TGACTTCTCC AAGTACCGGC AGCGAATCAA ACAGCACGCT 
GACGCGGTCC ACCTCATCTC GCGCGTGACA TTCCATTATA AGAGAAGCAG TCTGAGTTAC 
TTTGGAGGCG TGTGTTCTCG AATAAGAGGG GTTGGTGTGA ATGAGTATGG TCTTCCAATG 
GCGGTGGCAC AAGTATTATC ACAGAGCCTG GCTCAAAACC TTGGAATCCA GTGGGAACCT 
TCGAGCAGGA AGCCAAAATG TGAATGCATA GAGTCCTGGG GCGGCTGCAT CATGGAAGAA 
ACAGGGGTGT CCCACTCTCG AAAGTTCTCA AAGTGCAGCA TTTTGGAGTA CAGAGACTTT 
TTACAGAGAG GTGGCGGAGC ATGTCTTTTC AATAGGCCAA CTAAGCTGTT TGAGCCCACG 
GAATGTGGAA ATGGATATGT GGAGGCCGGG GAGGAATGCG ACTGTGGTTT CCATGTGGAA 
TGCTATGGAG TTTGCTGTAA GAAGTGTTCG CTCTCCAATG GGGCCCACTG CAGTGACGGC 
CCCTGCTGTA ACAACACCTC ATGTCTTTTT CAGTCACGAG GGTATGAATG TCGGGATGCC 
GTAAACAGCT GTGATATCAC CGAGTACTGC ACTGGAGACT CTGGCCAGTG CCCACCGAAC 
CTCCATAAAC AAGATGGCTA TAGCTGCAAT CAAAATCAGG GTCGCTGCTA CAATGGCGAG 
TGCAAGACAA GGGACAATCA ATGCCAGTAC ATCTGGGGGA CAAAGGCTGC GGGGTCAGAC 
AAGTTCTGCT ATGAAAAGCT GAACACGGAA GGCACCGAGA AGGGCAATTG TGGAAAGGAT 
GGAGACCGGT GGATCCCGTG CAGCAAGCAT GATGTGTTCT GTGGATTTCT GCTTTGCACC 
AATCTTACCC GAGCTCCACG TATCGGTCAA CTTCAAGGAG AGATCATCCC GACTTCCTTC 
TATCATCAAG GCCGAGTGAT TGACTGCAGT GGTGCTCATG TAGTTTTAGA CGATGATACA 
GACGTGGGTT ACGTTGAAGA TGGGACTCCG TGTGGCCCCT CCATGATGTG CTTAGATCGG 
AAGTGCCTAC AGATTCAAGC CCTGAATATG AGCAGCTGCC CACTTGACTC AAGGGGTAAA 
GTCTGCTCCG GCCACGGGGT GTGTAGCAAC GAAGCCACCT GCATCTGTGA TTTCACTTGG 
GCAGGCACAG ACTGCAGCAT CCGGGATCCA GTTCGGAACC CCAACCCCCC TAAGGATGAA 
GGCCCTAAGG TGAACATGGC CACGAGCAGG CTCATAGGGG CCGTGGCTGG CACCGTTCTG 
GCCCTGGGGG TGATTTTTGG AGGCACAGGG TGGGGCATAG AAAACGTCAA GAAGAGGAGA 
TTCGATCCCA CTCAGCAAGG CCCCATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adam23 ( XM_006495970.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006496033.1 Mus musculus a disintegrin and metallopeptidase domain 23 (Adam23), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu27414
Clone ID Related Accession (Same CDS sequence)	XM_006495970.3 , XM_006495970.4
Accession Version	XM_006495970.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2490bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	disintegrin and metalloproteinase domain-containing protein 23 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006495970.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCCGC CCGGCAGCAT CTCCCGGCGG CCGACCCTGA CGGGTTGCAG CCTTCCCGGC 
GCCTCCTGCG GCCCCGGCCG CTGCCCCGCC GGCCCGGTGC CGGCCCGCGC GCCGCCCTGC 
CGCCTGCTCC TCGTCCTTCT CCTGCTACCT GCGCTCGCCA CCTCATCCCG GCCCCGTGCC 
CGGGGGGCCG CTGCGCCCAG CGCTCCGCAC TGGAATGAAA CTGCAGAAAA AACCCTGGGA 
GTCCTGGCAG ATGAAGACAA CACATTGCAA CAAAATAGCA GCAGCAGAAA TACCAGCTAC 
AGCAGTGCAG TGCAAAAAGA AATCACACTG CCTTCAAGAC TGGTGTATTA CATCAACCAG 
GACTCAGAAA GCCCCTATCA TGTTCTTGAC ACAAAGGCCA GACACCAACA GAAACACAAT 
AAGGCTGTGC ATCTGGCCCA GGCAAGCTTC CAGATCGAAG CTTTCGGCTC CAAGTTCATT 
CTTGACCTCA CACTGAACAA TGGTTTGCTA TCTTCTGACT ACGTGGAGAT CCACTATGAA 
GACGGGAAGC AGATGTACTC TAAGGGTGGA GAGCACTGTT ACTACCACGG AAGCATCAGA 
GGCGTCAAGG ATTCCAGGGT GGCTCTATCG ACCTGCAATG GACTCCATGG CATGTTTGAG 
GATGACACCT TTGTGTATAT GATAGAGCCG CTGGAACTGA CTGATGATGA GAAAAGCACA 
GGCCGACCAC ACATAATCCA GAAAACCTTG GCAGGACAGT ATTCTAAGCA GATGAAGAAT 
CTCAGCACAG ATGGCAGTGA CCAGTGGCCT TTGCTACCTG AATTACAATG GCTGAGAAGA 
AGGAAAAGAG CGGTCAATCC ATCTCGTGGT GTGTTTGAAG AAATGAAGTA TTTGGAGCTT 
ATGATTGTTA ATGATCACAA GACGTATAAG AAGCACCGCT CTTCTCACGC GCATACCAAC 
AACTTCGCAA AGTCTGTGGT CAACCTTGTA GATTCTATTT ACAAGGAACA GCTCAACACC 
AGGGTTGTCC TGGTGGCTGT CGAGACCTGG ACCGAGAAGG ATCACATTGA CATCACCATC 
AACCCCGTGC AGATGCTACA TGACTTCTCC AAGTACCGGC AGCGAATCAA ACAGCACGCT 
GACGCGGTCC ACCTCATCTC GCGCGTGACA TTCCATTATA AGAGAAGCAG TCTGAGTTAC 
TTTGGAGGCG TGTGTTCTCG AATAAGAGGG GTTGGTGTGA ATGAGTATGG TCTTCCAATG 
GCGGTGGCAC AAGTATTATC ACAGAGCCTG GCTCAAAACC TTGGAATCCA GTGGGAACCT 
TCGAGCAGGA AGCCAAAATG TGAATGCATA GAGTCCTGGG GCGGCTGCAT CATGGAAGAA 
ACAGGGGTGT CCCACTCTCG AAAGTTCTCA AAGTGCAGCA TTTTGGAGTA CAGAGACTTT 
TTACAGAGAG GTGGCGGAGC ATGTCTTTTC AATAGGCCAA CTAAGCTGTT TGAGCCCACG 
GAATGTGGAA ATGGATATGT GGAGGCCGGG GAGGAATGCG ACTGTGGTTT CCATGTGGAA 
TGCTATGGAG TTTGCTGTAA GAAGTGTTCG CTCTCCAATG GGGCCCACTG CAGTGACGGC 
CCCTGCTGTA ACAACACCTC ATGTCTTTTT CAGTCACGAG GGTATGAATG TCGGGATGCC 
GTAAACAGCT GTGATATCAC CGAGTACTGC ACTGGAGACT CTGGCCAGTG CCCACCGAAC 
CTCCATAAAC AAGATGGCTA TAGCTGCAAT CAAAATCAGG GTCGCTGCTA CAATGGCGAG 
TGCAAGACAA GGGACAATCA ATGCCAGTAC ATCTGGGGGA CAAAGGCTGC GGGGTCAGAC 
AAGTTCTGCT ATGAAAAGCT GAACACGGAA GGCACCGAGA AGGGCAATTG TGGAAAGGAT 
GGAGACCGGT GGATCCCGTG CAGCAAGCAT GATGTGTTCT GTGGATTTCT GCTTTGCACC 
AATCTTACCC GAGCTCCACG TATCGGTCAA CTTCAAGGAG AGATCATCCC GACTTCCTTC 
TATCATCAAG GCCGAGTGAT TGACTGCAGT GGTGCTCATG TAGTTTTAGA CGATGATACA 
GACGTGGGTT ACGTTGAAGA TGGGACTCCG TGTGGCCCCT CCATGATGTG CTTAGATCGG 
AAGTGCCTAC AGATTCAAGC CCTGAATATG AGCAGCTGCC CACTTGACTC AAGGGGTAAA 
GTCTGCTCCG GCCACGGGGT GTGTAGCAAC GAAGCCACCT GCATCTGTGA TTTCACTTGG 
GCAGGCACAG ACTGCAGCAT CCGGGATCCA GTTCGGAACC CCAACCCCCC TAAGGATGAA 
GGCCCTAAGG AAACGTCAAG AAGAGGAGAT TCGATCCCAC TCAGCAAGGC CCCATCTGAA 
TCGTCTGCAC TGGAGGAATG CCACCTTGCA CTGTTGGGTT CTGGGAATGA CATGTTTTCA 
GCCATGCTGC CGGAACTCTT AAGTCTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006496033.1
CDS	495..2984
Translation	MKPPGSISRRPTLTGCSLPGASCGPGRCPAGPVPARAPPCRLLLVLLLLPALATSSRPRARGAAAPSAPHWNETAEKTLGVLADEDNTLQQNSSSRNTSYSSAVQKEITLPSRLVYYINQDSESPYHVLDTKARHQQKHNKAVHLAQASFQIEAFGSKFILDLTLNNGLLSSDYVEIHYEDGKQMYSKGGEHCYYHGSIRGVKDSRVALSTCNGLHGMFEDDTFVYMIEPLELTDDEKSTGRPHIIQKTLAGQYSKQMKNLSTDGSDQWPLLPELQWLRRRKRAVNPSRGVFEEMKYLELMIVNDHKTYKKHRSSHAHTNNFAKSVVNLVDSIYKEQLNTRVVLVAVETWTEKDHIDITINPVQMLHDFSKYRQRIKQHADAVHLISRVTFHYKRSSLSYFGGVCSRIRGVGVNEYGLPMAVAQVLSQSLAQNLGIQWEPSSRKPKCECIESWGGCIMEETGVSHSRKFSKCSILEYRDFLQRGGGACLFNRPTKLFEPTECGNGYVEAGEECDCGFHVECYGVCCKKCSLSNGAHCSDGPCCNNTSCLFQSRGYECRDAVNSCDITEYCTGDSGQCPPNLHKQDGYSCNQNQGRCYNGECKTRDNQCQYIWGTKAAGSDKFCYEKLNTEGTEKGNCGKDGDRWIPCSKHDVFCGFLLCTNLTRAPRIGQLQGEIIPTSFYHQGRVIDCSGAHVVLDDDTDVGYVEDGTPCGPSMMCLDRKCLQIQALNMSSCPLDSRGKVCSGHGVCSNEATCICDFTWAGTDCSIRDPVRNPNPPKDEGPKETSRRGDSIPLSKAPSESSALEECHLALLGSGNDMFSAMLPELLSL

Target ORF information:

RefSeq Version	XM_006495970.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus a disintegrin and metallopeptidase domain 23 (Adam23), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006495970.4

ORF Insert Sequence:

ATGAAGCCGC CCGGCAGCAT CTCCCGGCGG CCGACCCTGA CGGGTTGCAG CCTTCCCGGC 
GCCTCCTGCG GCCCCGGCCG CTGCCCCGCC GGCCCGGTGC CGGCCCGCGC GCCGCCCTGC 
CGCCTGCTCC TCGTCCTTCT CCTGCTACCT GCGCTCGCCA CCTCATCCCG GCCCCGTGCC 
CGGGGGGCCG CTGCGCCCAG CGCTCCGCAC TGGAATGAAA CTGCAGAAAA AACCCTGGGA 
GTCCTGGCAG ATGAAGACAA CACATTGCAA CAAAATAGCA GCAGCAGAAA TACCAGCTAC 
AGCAGTGCAG TGCAAAAAGA AATCACACTG CCTTCAAGAC TGGTGTATTA CATCAACCAG 
GACTCAGAAA GCCCCTATCA TGTTCTTGAC ACAAAGGCCA GACACCAACA GAAACACAAT 
AAGGCTGTGC ATCTGGCCCA GGCAAGCTTC CAGATCGAAG CTTTCGGCTC CAAGTTCATT 
CTTGACCTCA CACTGAACAA TGGTTTGCTA TCTTCTGACT ACGTGGAGAT CCACTATGAA 
GACGGGAAGC AGATGTACTC TAAGGGTGGA GAGCACTGTT ACTACCACGG AAGCATCAGA 
GGCGTCAAGG ATTCCAGGGT GGCTCTATCG ACCTGCAATG GACTCCATGG CATGTTTGAG 
GATGACACCT TTGTGTATAT GATAGAGCCG CTGGAACTGA CTGATGATGA GAAAAGCACA 
GGCCGACCAC ACATAATCCA GAAAACCTTG GCAGGACAGT ATTCTAAGCA GATGAAGAAT 
CTCAGCACAG ATGGCAGTGA CCAGTGGCCT TTGCTACCTG AATTACAATG GCTGAGAAGA 
AGGAAAAGAG CGGTCAATCC ATCTCGTGGT GTGTTTGAAG AAATGAAGTA TTTGGAGCTT 
ATGATTGTTA ATGATCACAA GACGTATAAG AAGCACCGCT CTTCTCACGC GCATACCAAC 
AACTTCGCAA AGTCTGTGGT CAACCTTGTA GATTCTATTT ACAAGGAACA GCTCAACACC 
AGGGTTGTCC TGGTGGCTGT CGAGACCTGG ACCGAGAAGG ATCACATTGA CATCACCATC 
AACCCCGTGC AGATGCTACA TGACTTCTCC AAGTACCGGC AGCGAATCAA ACAGCACGCT 
GACGCGGTCC ACCTCATCTC GCGCGTGACA TTCCATTATA AGAGAAGCAG TCTGAGTTAC 
TTTGGAGGCG TGTGTTCTCG AATAAGAGGG GTTGGTGTGA ATGAGTATGG TCTTCCAATG 
GCGGTGGCAC AAGTATTATC ACAGAGCCTG GCTCAAAACC TTGGAATCCA GTGGGAACCT 
TCGAGCAGGA AGCCAAAATG TGAATGCATA GAGTCCTGGG GCGGCTGCAT CATGGAAGAA 
ACAGGGGTGT CCCACTCTCG AAAGTTCTCA AAGTGCAGCA TTTTGGAGTA CAGAGACTTT 
TTACAGAGAG GTGGCGGAGC ATGTCTTTTC AATAGGCCAA CTAAGCTGTT TGAGCCCACG 
GAATGTGGAA ATGGATATGT GGAGGCCGGG GAGGAATGCG ACTGTGGTTT CCATGTGGAA 
TGCTATGGAG TTTGCTGTAA GAAGTGTTCG CTCTCCAATG GGGCCCACTG CAGTGACGGC 
CCCTGCTGTA ACAACACCTC ATGTCTTTTT CAGTCACGAG GGTATGAATG TCGGGATGCC 
GTAAACAGCT GTGATATCAC CGAGTACTGC ACTGGAGACT CTGGCCAGTG CCCACCGAAC 
CTCCATAAAC AAGATGGCTA TAGCTGCAAT CAAAATCAGG GTCGCTGCTA CAATGGCGAG 
TGCAAGACAA GGGACAATCA ATGCCAGTAC ATCTGGGGGA CAAAGGCTGC GGGGTCAGAC 
AAGTTCTGCT ATGAAAAGCT GAACACGGAA GGCACCGAGA AGGGCAATTG TGGAAAGGAT 
GGAGACCGGT GGATCCCGTG CAGCAAGCAT GATGTGTTCT GTGGATTTCT GCTTTGCACC 
AATCTTACCC GAGCTCCACG TATCGGTCAA CTTCAAGGAG AGATCATCCC GACTTCCTTC 
TATCATCAAG GCCGAGTGAT TGACTGCAGT GGTGCTCATG TAGTTTTAGA CGATGATACA 
GACGTGGGTT ACGTTGAAGA TGGGACTCCG TGTGGCCCCT CCATGATGTG CTTAGATCGG 
AAGTGCCTAC AGATTCAAGC CCTGAATATG AGCAGCTGCC CACTTGACTC AAGGGGTAAA 
GTCTGCTCCG GCCACGGGGT GTGTAGCAAC GAAGCCACCT GCATCTGTGA TTTCACTTGG 
GCAGGCACAG ACTGCAGCAT CCGGGATCCA GTTCGGAACC CCAACCCCCC TAAGGATGAA 
GGCCCTAAGG AAACGTCAAG AAGAGGAGAT TCGATCCCAC TCAGCAAGGC CCCATCTGAA 
TCGTCTGCAC TGGAGGAATG CCACCTTGCA CTGTTGGGTT CTGGGAATGA CATGTTTTCA 
GCCATGCTGC CGGAACTCTT AAGTCTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adam23 ( NM_011780.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035910.1 Mus musculus a disintegrin and metallopeptidase domain 23 (Adam23), mRNA.

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CloneID	OMu08823
Clone ID Related Accession (Same CDS sequence)	NM_011780.3
Accession Version	NM_011780.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2490bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Mus musculus(house mouse)
Product	disintegrin and metalloproteinase domain-containing protein 23 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK046677.1, AB009673.1, AL645534.20 and AW046396.1. On Sep 19, 2015 this sequence version replaced NM_011780.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB009673.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCCGC CCGGCAGCAT CTCCCGGCGG CCGACCCTGA CGGGTTGCAG CCTTCCCGGC 
GCCTCCTGCG GCCCCGGCCG CTGCCCCGCC GGCCCGGTGC CGGCCCGCGC GCCGCCCTGC 
CGCCTGCTCC TCGTCCTTCT CCTGCTACCT GCGCTCGCCA CCTCATCCCG GCCCCGTGCC 
CGGGGGGCCG CTGCGCCCAG CGCTCCGCAC TGGAATGAAA CTGCAGAAAA AACCCTGGGA 
GTCCTGGCAG ATGAAGACAA CACATTGCAA CAAAATAGCA GCAGCAGAAA TACCAGCTAC 
AGCAGTGCAG TGCAAAAAGA AATCACACTG CCTTCAAGAC TGGTGTATTA CATCAACCAG 
GACTCAGAAA GCCCCTATCA TGTTCTTGAC ACAAAGGCCA GACACCAACA GAAACACAAT 
AAGGCTGTGC ATCTGGCCCA GGCAAGCTTC CAGATCGAAG CTTTCGGCTC CAAGTTCATT 
CTTGACCTCA CACTGAACAA TGGTTTGCTA TCTTCTGACT ACGTGGAGAT CCACTATGAA 
GACGGGAAGC AGATGTACTC TAAGGGTGGA GAGCACTGTT ACTACCACGG AAGCATCAGA 
GGCGTCAAGG ATTCCAGGGT GGCTCTATCG ACCTGCAATG GACTCCATGG CATGTTTGAG 
GATGACACCT TTGTGTATAT GATAGAGCCG CTGGAACTGA CTGATGATGA GAAAAGCACA 
GGCCGACCAC ACATAATCCA GAAAACCTTG GCAGGACAGT ATTCTAAGCA GATGAAGAAT 
CTCAGCACAG ATGGCAGTGA CCAGTGGCCT TTGCTACCTG AATTACAATG GCTGAGAAGA 
AGGAAAAGAG CGGTCAATCC ATCTCGTGGT GTGTTTGAAG AAATGAAGTA TTTGGAGCTT 
ATGATTGTTA ATGATCACAA GACGTATAAG AAGCACCGCT CTTCTCACGC GCATACCAAC 
AACTTCGCAA AGTCTGTGGT CAACCTTGTA GATTCTATTT ACAAGGAACA GCTCAACACC 
AGGGTTGTCC TGGTGGCTGT CGAGACCTGG ACCGAGAAGG ATCACATTGA CATCACCATC 
AACCCCGTGC AGATGCTACA TGACTTCTCC AAGTACCGGC AGCGAATCAA ACAGCACGCT 
GACGCGGTCC ACCTCATCTC GCGCGTGACA TTCCATTATA AGAGAAGCAG TCTGAGTTAC 
TTTGGAGGCG TGTGTTCTCG AATAAGAGGG GTTGGTGTGA ATGAGTATGG TCTTCCAATG 
GCGGTGGCAC AAGTATTATC ACAGAGCCTG GCTCAAAACC TTGGAATCCA GTGGGAACCT 
TCGAGCAGGA AGCCAAAATG TGAATGCATA GAGTCCTGGG GCGGCTGCAT CATGGAAGAA 
ACAGGGGTGT CCCACTCTCG AAAGTTCTCA AAGTGCAGCA TTTTGGAGTA CAGAGACTTT 
TTACAGAGAG GTGGCGGAGC ATGTCTTTTC AATAGGCCAA CTAAGCTGTT TGAGCCCACG 
GAATGTGGAA ATGGATATGT GGAGGCCGGG GAGGAATGCG ACTGTGGTTT CCATGTGGAA 
TGCTATGGAG TTTGCTGTAA GAAGTGTTCG CTCTCCAATG GGGCCCACTG CAGTGACGGC 
CCCTGCTGTA ACAACACCTC ATGTCTTTTT CAGTCACGAG GGTATGAATG TCGGGATGCC 
GTAAACAGCT GTGATATCAC CGAGTACTGC ACTGGAGACT CTGGCCAGTG CCCACCGAAC 
CTCCATAAAC AAGATGGCTA TAGCTGCAAT CAAAATCAGG GTCGCTGCTA CAATGGCGAG 
TGCAAGACAA GGGACAATCA ATGCCAGTAC ATCTGGGGGA CAAAGGCTGC GGGGTCAGAC 
AAGTTCTGCT ATGAAAAGCT GAACACGGAA GGCACCGAGA AGGGCAATTG TGGAAAGGAT 
GGAGACCGGT GGATCCCGTG CAGCAAGCAT GATGTGTTCT GTGGATTTCT GCTTTGCACC 
AATCTTACCC GAGCTCCACG TATCGGTCAA CTTCAAGGAG AGATCATCCC GACTTCCTTC 
TATCATCAAG GCCGAGTGAT TGACTGCAGT GGTGCTCATG TAGTTTTAGA CGATGATACA 
GACGTGGGTT ACGTTGAAGA TGGGACTCCG TGTGGCCCCT CCATGATGTG CTTAGATCGG 
AAGTGCCTAC AGATTCAAGC CCTGAATATG AGCAGCTGCC CACTTGACTC AAGGGGTAAA 
GTCTGCTCCG GCCACGGGGT GTGTAGCAAC GAAGCCACCT GCATCTGTGA TTTCACTTGG 
GCAGGCACAG ACTGCAGCAT CCGGGATCCA GTTCGGAACC CCAACCCCCC TAAGGATGAA 
GGCCCTAAGG GTCCTAGCGC CACCAATCTC ATAATAGGCT CCATCGCTGG TGCCATCCTG 
GTAGCAGCTA TTGTCCTTGG GGGCACAGGC TGGGGATTTA AAAACGTCAA GAAGAGGAGA 
TTCGATCCCA CTCAGCAAGG CCCCATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035910.1
CDS	321..2810
Translation	MKPPGSISRRPTLTGCSLPGASCGPGRCPAGPVPARAPPCRLLLVLLLLPALATSSRPRARGAAAPSAPHWNETAEKTLGVLADEDNTLQQNSSSRNTSYSSAVQKEITLPSRLVYYINQDSESPYHVLDTKARHQQKHNKAVHLAQASFQIEAFGSKFILDLTLNNGLLSSDYVEIHYEDGKQMYSKGGEHCYYHGSIRGVKDSRVALSTCNGLHGMFEDDTFVYMIEPLELTDDEKSTGRPHIIQKTLAGQYSKQMKNLSTDGSDQWPLLPELQWLRRRKRAVNPSRGVFEEMKYLELMIVNDHKTYKKHRSSHAHTNNFAKSVVNLVDSIYKEQLNTRVVLVAVETWTEKDHIDITINPVQMLHDFSKYRQRIKQHADAVHLISRVTFHYKRSSLSYFGGVCSRIRGVGVNEYGLPMAVAQVLSQSLAQNLGIQWEPSSRKPKCECIESWGGCIMEETGVSHSRKFSKCSILEYRDFLQRGGGACLFNRPTKLFEPTECGNGYVEAGEECDCGFHVECYGVCCKKCSLSNGAHCSDGPCCNNTSCLFQSRGYECRDAVNSCDITEYCTGDSGQCPPNLHKQDGYSCNQNQGRCYNGECKTRDNQCQYIWGTKAAGSDKFCYEKLNTEGTEKGNCGKDGDRWIPCSKHDVFCGFLLCTNLTRAPRIGQLQGEIIPTSFYHQGRVIDCSGAHVVLDDDTDVGYVEDGTPCGPSMMCLDRKCLQIQALNMSSCPLDSRGKVCSGHGVCSNEATCICDFTWAGTDCSIRDPVRNPNPPKDEGPKGPSATNLIIGSIAGAILVAAIVLGGTGWGFKNVKKRRFDPTQQGPI

Target ORF information:

RefSeq Version	NM_011780.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus a disintegrin and metallopeptidase domain 23 (Adam23), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011780.3

ORF Insert Sequence:

ATGAAGCCGC CCGGCAGCAT CTCCCGGCGG CCGACCCTGA CGGGTTGCAG CCTTCCCGGC 
GCCTCCTGCG GCCCCGGCCG CTGCCCCGCC GGCCCGGTGC CGGCCCGCGC GCCGCCCTGC 
CGCCTGCTCC TCGTCCTTCT CCTGCTACCT GCGCTCGCCA CCTCATCCCG GCCCCGTGCC 
CGGGGGGCCG CTGCGCCCAG CGCTCCGCAC TGGAATGAAA CTGCAGAAAA AACCCTGGGA 
GTCCTGGCAG ATGAAGACAA CACATTGCAA CAAAATAGCA GCAGCAGAAA TACCAGCTAC 
AGCAGTGCAG TGCAAAAAGA AATCACACTG CCTTCAAGAC TGGTGTATTA CATCAACCAG 
GACTCAGAAA GCCCCTATCA TGTTCTTGAC ACAAAGGCCA GACACCAACA GAAACACAAT 
AAGGCTGTGC ATCTGGCCCA GGCAAGCTTC CAGATCGAAG CTTTCGGCTC CAAGTTCATT 
CTTGACCTCA CACTGAACAA TGGTTTGCTA TCTTCTGACT ACGTGGAGAT CCACTATGAA 
GACGGGAAGC AGATGTACTC TAAGGGTGGA GAGCACTGTT ACTACCACGG AAGCATCAGA 
GGCGTCAAGG ATTCCAGGGT GGCTCTATCG ACCTGCAATG GACTCCATGG CATGTTTGAG 
GATGACACCT TTGTGTATAT GATAGAGCCG CTGGAACTGA CTGATGATGA GAAAAGCACA 
GGCCGACCAC ACATAATCCA GAAAACCTTG GCAGGACAGT ATTCTAAGCA GATGAAGAAT 
CTCAGCACAG ATGGCAGTGA CCAGTGGCCT TTGCTACCTG AATTACAATG GCTGAGAAGA 
AGGAAAAGAG CGGTCAATCC ATCTCGTGGT GTGTTTGAAG AAATGAAGTA TTTGGAGCTT 
ATGATTGTTA ATGATCACAA GACGTATAAG AAGCACCGCT CTTCTCACGC GCATACCAAC 
AACTTCGCAA AGTCTGTGGT CAACCTTGTA GATTCTATTT ACAAGGAACA GCTCAACACC 
AGGGTTGTCC TGGTGGCTGT CGAGACCTGG ACCGAGAAGG ATCACATTGA CATCACCATC 
AACCCCGTGC AGATGCTACA TGACTTCTCC AAGTACCGGC AGCGAATCAA ACAGCACGCT 
GACGCGGTCC ACCTCATCTC GCGCGTGACA TTCCATTATA AGAGAAGCAG TCTGAGTTAC 
TTTGGAGGCG TGTGTTCTCG AATAAGAGGG GTTGGTGTGA ATGAGTATGG TCTTCCAATG 
GCGGTGGCAC AAGTATTATC ACAGAGCCTG GCTCAAAACC TTGGAATCCA GTGGGAACCT 
TCGAGCAGGA AGCCAAAATG TGAATGCATA GAGTCCTGGG GCGGCTGCAT CATGGAAGAA 
ACAGGGGTGT CCCACTCTCG AAAGTTCTCA AAGTGCAGCA TTTTGGAGTA CAGAGACTTT 
TTACAGAGAG GTGGCGGAGC ATGTCTTTTC AATAGGCCAA CTAAGCTGTT TGAGCCCACG 
GAATGTGGAA ATGGATATGT GGAGGCCGGG GAGGAATGCG ACTGTGGTTT CCATGTGGAA 
TGCTATGGAG TTTGCTGTAA GAAGTGTTCG CTCTCCAATG GGGCCCACTG CAGTGACGGC 
CCCTGCTGTA ACAACACCTC ATGTCTTTTT CAGTCACGAG GGTATGAATG TCGGGATGCC 
GTAAACAGCT GTGATATCAC CGAGTACTGC ACTGGAGACT CTGGCCAGTG CCCACCGAAC 
CTCCATAAAC AAGATGGCTA TAGCTGCAAT CAAAATCAGG GTCGCTGCTA CAATGGCGAG 
TGCAAGACAA GGGACAATCA ATGCCAGTAC ATCTGGGGGA CAAAGGCTGC GGGGTCAGAC 
AAGTTCTGCT ATGAAAAGCT GAACACGGAA GGCACCGAGA AGGGCAATTG TGGAAAGGAT 
GGAGACCGGT GGATCCCGTG CAGCAAGCAT GATGTGTTCT GTGGATTTCT GCTTTGCACC 
AATCTTACCC GAGCTCCACG TATCGGTCAA CTTCAAGGAG AGATCATCCC GACTTCCTTC 
TATCATCAAG GCCGAGTGAT TGACTGCAGT GGTGCTCATG TAGTTTTAGA CGATGATACA 
GACGTGGGTT ACGTTGAAGA TGGGACTCCG TGTGGCCCCT CCATGATGTG CTTAGATCGG 
AAGTGCCTAC AGATTCAAGC CCTGAATATG AGCAGCTGCC CACTTGACTC AAGGGGTAAA 
GTCTGCTCCG GCCACGGGGT GTGTAGCAAC GAAGCCACCT GCATCTGTGA TTTCACTTGG 
GCAGGCACAG ACTGCAGCAT CCGGGATCCA GTTCGGAACC CCAACCCCCC TAAGGATGAA 
GGCCCTAAGG GTCCTAGCGC CACCAATCTC ATAATAGGCT CCATCGCTGG TGCCATCCTG 
GTAGCAGCTA TTGTCCTTGG GGGCACAGGC TGGGGATTTA AAAACGTCAA GAAGAGGAGA 
TTCGATCCCA CTCAGCAAGG CCCCATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adam23 ( XM_006495969.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006496032.1 Mus musculus a disintegrin and metallopeptidase domain 23 (Adam23), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu27413
Clone ID Related Accession (Same CDS sequence)	XM_006495969.4 , XM_006495969.3
Accession Version	XM_006495969.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2490bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	disintegrin and metalloproteinase domain-containing protein 23 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006495969.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCCGC CCGGCAGCAT CTCCCGGCGG CCGACCCTGA CGGGTTGCAG CCTTCCCGGC 
GCCTCCTGCG GCCCCGGCCG CTGCCCCGCC GGCCCGGTGC CGGCCCGCGC GCCGCCCTGC 
CGCCTGCTCC TCGTCCTTCT CCTGCTACCT GCGCTCGCCA CCTCATCCCG GCCCCGTGCC 
CGGGGGGCCG CTGCGCCCAG CGCTCCGCAC TGGAATGAAA CTGCAGAAAA AACCCTGGGA 
GTCCTGGCAG ATGAAGACAA CACATTGCAA CAAAATAGCA GCAGCAGAAA TACCAGCTAC 
AGCAGTGCAG TGCAAAAAGA AATCACACTG CCTTCAAGAC TGGTGTATTA CATCAACCAG 
GACTCAGAAA GCCCCTATCA TGTTCTTGAC ACAAAGGCCA GACACCAACA GAAACACAAT 
AAGGCTGTGC ATCTGGCCCA GGCAAGCTTC CAGATCGAAG CTTTCGGCTC CAAGTTCATT 
CTTGACCTCA CACTGAACAA TGGTTTGCTA TCTTCTGACT ACGTGGAGAT CCACTATGAA 
GACGGGAAGC AGATGTACTC TAAGGGTGGA GAGCACTGTT ACTACCACGG AAGCATCAGA 
GGCGTCAAGG ATTCCAGGGT GGCTCTATCG ACCTGCAATG GACTCCATGG CATGTTTGAG 
GATGACACCT TTGTGTATAT GATAGAGCCG CTGGAACTGA CTGATGATGA GAAAAGCACA 
GGCCGACCAC ACATAATCCA GAAAACCTTG GCAGGACAGT ATTCTAAGCA GATGAAGAAT 
CTCAGCACAG ATGGCAGTGA CCAGTGGCCT TTGCTACCTG AATTACAATG GCTGAGAAGA 
AGGAAAAGAG CGGTCAATCC ATCTCGTGGT GTGTTTGAAG AAATGAAGTA TTTGGAGCTT 
ATGATTGTTA ATGATCACAA GACGTATAAG AAGCACCGCT CTTCTCACGC GCATACCAAC 
AACTTCGCAA AGTCTGTGGT CAACCTTGTA GATTCTATTT ACAAGGAACA GCTCAACACC 
AGGGTTGTCC TGGTGGCTGT CGAGACCTGG ACCGAGAAGG ATCACATTGA CATCACCATC 
AACCCCGTGC AGATGCTACA TGACTTCTCC AAGTACCGGC AGCGAATCAA ACAGCACGCT 
GACGCGGTCC ACCTCATCTC GCGCGTGACA TTCCATTATA AGAGAAGCAG TCTGAGTTAC 
TTTGGAGGCG TGTGTTCTCG AATAAGAGGG GTTGGTGTGA ATGAGTATGG TCTTCCAATG 
GCGGTGGCAC AAGTATTATC ACAGAGCCTG GCTCAAAACC TTGGAATCCA GTGGGAACCT 
TCGAGCAGGA AGCCAAAATG TGAATGCATA GAGTCCTGGG GCGGCTGCAT CATGGAAGAA 
ACAGGGGTGT CCCACTCTCG AAAGTTCTCA AAGTGCAGCA TTTTGGAGTA CAGAGACTTT 
TTACAGAGAG GTGGCGGAGC ATGTCTTTTC AATAGGCCAA CTAAGCTGTT TGAGCCCACG 
GAATGTGGAA ATGGATATGT GGAGGCCGGG GAGGAATGCG ACTGTGGTTT CCATGTGGAA 
TGCTATGGAG TTTGCTGTAA GAAGTGTTCG CTCTCCAATG GGGCCCACTG CAGTGACGGC 
CCCTGCTGTA ACAACACCTC ATGTCTTTTT CAGTCACGAG GGTATGAATG TCGGGATGCC 
GTAAACAGCT GTGATATCAC CGAGTACTGC ACTGGAGACT CTGGCCAGTG CCCACCGAAC 
CTCCATAAAC AAGATGGCTA TAGCTGCAAT CAAAATCAGG GTCGCTGCTA CAATGGCGAG 
TGCAAGACAA GGGACAATCA ATGCCAGTAC ATCTGGGGGA CAAAGGCTGC GGGGTCAGAC 
AAGTTCTGCT ATGAAAAGCT GAACACGGAA GGCACCGAGA AGGGCAATTG TGGAAAGGAT 
GGAGACCGGT GGATCCCGTG CAGCAAGCAT GATGTGTTCT GTGGATTTCT GCTTTGCACC 
AATCTTACCC GAGCTCCACG TATCGGTCAA CTTCAAGGAG AGATCATCCC GACTTCCTTC 
TATCATCAAG GCCGAGTGAT TGACTGCAGT GGTGCTCATG TAGTTTTAGA CGATGATACA 
GACGTGGGTT ACGTTGAAGA TGGGACTCCG TGTGGCCCCT CCATGATGTG CTTAGATCGG 
AAGTGCCTAC AGATTCAAGC CCTGAATATG AGCAGCTGCC CACTTGACTC AAGGGGTAAA 
GTCTGCTCCG GCCACGGGGT GTGTAGCAAC GAAGCCACCT GCATCTGTGA TTTCACTTGG 
GCAGGCACAG ACTGCAGCAT CCGGGATCCA GTTCGGAACC CCAACCCCCC TAAGGATGAA 
GGCCCTAAGG TGAACATGGC CACGAGCAGG CTCATAGGGG CCGTGGCTGG CACCGTTCTG 
GCCCTGGGGG TGATTTTTGG AGGCACAGGG TGGGGCATAG AAAACGTCAA GAAGAGGAGA 
TTCGATCCCA CTCAGCAAGG CCCCATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006496032.1
CDS	330..2819
Translation	MKPPGSISRRPTLTGCSLPGASCGPGRCPAGPVPARAPPCRLLLVLLLLPALATSSRPRARGAAAPSAPHWNETAEKTLGVLADEDNTLQQNSSSRNTSYSSAVQKEITLPSRLVYYINQDSESPYHVLDTKARHQQKHNKAVHLAQASFQIEAFGSKFILDLTLNNGLLSSDYVEIHYEDGKQMYSKGGEHCYYHGSIRGVKDSRVALSTCNGLHGMFEDDTFVYMIEPLELTDDEKSTGRPHIIQKTLAGQYSKQMKNLSTDGSDQWPLLPELQWLRRRKRAVNPSRGVFEEMKYLELMIVNDHKTYKKHRSSHAHTNNFAKSVVNLVDSIYKEQLNTRVVLVAVETWTEKDHIDITINPVQMLHDFSKYRQRIKQHADAVHLISRVTFHYKRSSLSYFGGVCSRIRGVGVNEYGLPMAVAQVLSQSLAQNLGIQWEPSSRKPKCECIESWGGCIMEETGVSHSRKFSKCSILEYRDFLQRGGGACLFNRPTKLFEPTECGNGYVEAGEECDCGFHVECYGVCCKKCSLSNGAHCSDGPCCNNTSCLFQSRGYECRDAVNSCDITEYCTGDSGQCPPNLHKQDGYSCNQNQGRCYNGECKTRDNQCQYIWGTKAAGSDKFCYEKLNTEGTEKGNCGKDGDRWIPCSKHDVFCGFLLCTNLTRAPRIGQLQGEIIPTSFYHQGRVIDCSGAHVVLDDDTDVGYVEDGTPCGPSMMCLDRKCLQIQALNMSSCPLDSRGKVCSGHGVCSNEATCICDFTWAGTDCSIRDPVRNPNPPKDEGPKVNMATSRLIGAVAGTVLALGVIFGGTGWGIENVKKRRFDPTQQGPI

Target ORF information:

RefSeq Version	XM_006495969.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus a disintegrin and metallopeptidase domain 23 (Adam23), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006495969.3

ORF Insert Sequence:

ATGAAGCCGC CCGGCAGCAT CTCCCGGCGG CCGACCCTGA CGGGTTGCAG CCTTCCCGGC 
GCCTCCTGCG GCCCCGGCCG CTGCCCCGCC GGCCCGGTGC CGGCCCGCGC GCCGCCCTGC 
CGCCTGCTCC TCGTCCTTCT CCTGCTACCT GCGCTCGCCA CCTCATCCCG GCCCCGTGCC 
CGGGGGGCCG CTGCGCCCAG CGCTCCGCAC TGGAATGAAA CTGCAGAAAA AACCCTGGGA 
GTCCTGGCAG ATGAAGACAA CACATTGCAA CAAAATAGCA GCAGCAGAAA TACCAGCTAC 
AGCAGTGCAG TGCAAAAAGA AATCACACTG CCTTCAAGAC TGGTGTATTA CATCAACCAG 
GACTCAGAAA GCCCCTATCA TGTTCTTGAC ACAAAGGCCA GACACCAACA GAAACACAAT 
AAGGCTGTGC ATCTGGCCCA GGCAAGCTTC CAGATCGAAG CTTTCGGCTC CAAGTTCATT 
CTTGACCTCA CACTGAACAA TGGTTTGCTA TCTTCTGACT ACGTGGAGAT CCACTATGAA 
GACGGGAAGC AGATGTACTC TAAGGGTGGA GAGCACTGTT ACTACCACGG AAGCATCAGA 
GGCGTCAAGG ATTCCAGGGT GGCTCTATCG ACCTGCAATG GACTCCATGG CATGTTTGAG 
GATGACACCT TTGTGTATAT GATAGAGCCG CTGGAACTGA CTGATGATGA GAAAAGCACA 
GGCCGACCAC ACATAATCCA GAAAACCTTG GCAGGACAGT ATTCTAAGCA GATGAAGAAT 
CTCAGCACAG ATGGCAGTGA CCAGTGGCCT TTGCTACCTG AATTACAATG GCTGAGAAGA 
AGGAAAAGAG CGGTCAATCC ATCTCGTGGT GTGTTTGAAG AAATGAAGTA TTTGGAGCTT 
ATGATTGTTA ATGATCACAA GACGTATAAG AAGCACCGCT CTTCTCACGC GCATACCAAC 
AACTTCGCAA AGTCTGTGGT CAACCTTGTA GATTCTATTT ACAAGGAACA GCTCAACACC 
AGGGTTGTCC TGGTGGCTGT CGAGACCTGG ACCGAGAAGG ATCACATTGA CATCACCATC 
AACCCCGTGC AGATGCTACA TGACTTCTCC AAGTACCGGC AGCGAATCAA ACAGCACGCT 
GACGCGGTCC ACCTCATCTC GCGCGTGACA TTCCATTATA AGAGAAGCAG TCTGAGTTAC 
TTTGGAGGCG TGTGTTCTCG AATAAGAGGG GTTGGTGTGA ATGAGTATGG TCTTCCAATG 
GCGGTGGCAC AAGTATTATC ACAGAGCCTG GCTCAAAACC TTGGAATCCA GTGGGAACCT 
TCGAGCAGGA AGCCAAAATG TGAATGCATA GAGTCCTGGG GCGGCTGCAT CATGGAAGAA 
ACAGGGGTGT CCCACTCTCG AAAGTTCTCA AAGTGCAGCA TTTTGGAGTA CAGAGACTTT 
TTACAGAGAG GTGGCGGAGC ATGTCTTTTC AATAGGCCAA CTAAGCTGTT TGAGCCCACG 
GAATGTGGAA ATGGATATGT GGAGGCCGGG GAGGAATGCG ACTGTGGTTT CCATGTGGAA 
TGCTATGGAG TTTGCTGTAA GAAGTGTTCG CTCTCCAATG GGGCCCACTG CAGTGACGGC 
CCCTGCTGTA ACAACACCTC ATGTCTTTTT CAGTCACGAG GGTATGAATG TCGGGATGCC 
GTAAACAGCT GTGATATCAC CGAGTACTGC ACTGGAGACT CTGGCCAGTG CCCACCGAAC 
CTCCATAAAC AAGATGGCTA TAGCTGCAAT CAAAATCAGG GTCGCTGCTA CAATGGCGAG 
TGCAAGACAA GGGACAATCA ATGCCAGTAC ATCTGGGGGA CAAAGGCTGC GGGGTCAGAC 
AAGTTCTGCT ATGAAAAGCT GAACACGGAA GGCACCGAGA AGGGCAATTG TGGAAAGGAT 
GGAGACCGGT GGATCCCGTG CAGCAAGCAT GATGTGTTCT GTGGATTTCT GCTTTGCACC 
AATCTTACCC GAGCTCCACG TATCGGTCAA CTTCAAGGAG AGATCATCCC GACTTCCTTC 
TATCATCAAG GCCGAGTGAT TGACTGCAGT GGTGCTCATG TAGTTTTAGA CGATGATACA 
GACGTGGGTT ACGTTGAAGA TGGGACTCCG TGTGGCCCCT CCATGATGTG CTTAGATCGG 
AAGTGCCTAC AGATTCAAGC CCTGAATATG AGCAGCTGCC CACTTGACTC AAGGGGTAAA 
GTCTGCTCCG GCCACGGGGT GTGTAGCAAC GAAGCCACCT GCATCTGTGA TTTCACTTGG 
GCAGGCACAG ACTGCAGCAT CCGGGATCCA GTTCGGAACC CCAACCCCCC TAAGGATGAA 
GGCCCTAAGG TGAACATGGC CACGAGCAGG CTCATAGGGG CCGTGGCTGG CACCGTTCTG 
GCCCTGGGGG TGATTTTTGG AGGCACAGGG TGGGGCATAG AAAACGTCAA GAAGAGGAGA 
TTCGATCCCA CTCAGCAAGG CCCCATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adam23 ( XM_006495970.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006496033.1 Mus musculus a disintegrin and metallopeptidase domain 23 (Adam23), transcript variant X2, mRNA.

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CloneID	OMu27414
Clone ID Related Accession (Same CDS sequence)	XM_006495970.3 , XM_006495970.4
Accession Version	XM_006495970.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2490bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	disintegrin and metalloproteinase domain-containing protein 23 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006495970.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCCGC CCGGCAGCAT CTCCCGGCGG CCGACCCTGA CGGGTTGCAG CCTTCCCGGC 
GCCTCCTGCG GCCCCGGCCG CTGCCCCGCC GGCCCGGTGC CGGCCCGCGC GCCGCCCTGC 
CGCCTGCTCC TCGTCCTTCT CCTGCTACCT GCGCTCGCCA CCTCATCCCG GCCCCGTGCC 
CGGGGGGCCG CTGCGCCCAG CGCTCCGCAC TGGAATGAAA CTGCAGAAAA AACCCTGGGA 
GTCCTGGCAG ATGAAGACAA CACATTGCAA CAAAATAGCA GCAGCAGAAA TACCAGCTAC 
AGCAGTGCAG TGCAAAAAGA AATCACACTG CCTTCAAGAC TGGTGTATTA CATCAACCAG 
GACTCAGAAA GCCCCTATCA TGTTCTTGAC ACAAAGGCCA GACACCAACA GAAACACAAT 
AAGGCTGTGC ATCTGGCCCA GGCAAGCTTC CAGATCGAAG CTTTCGGCTC CAAGTTCATT 
CTTGACCTCA CACTGAACAA TGGTTTGCTA TCTTCTGACT ACGTGGAGAT CCACTATGAA 
GACGGGAAGC AGATGTACTC TAAGGGTGGA GAGCACTGTT ACTACCACGG AAGCATCAGA 
GGCGTCAAGG ATTCCAGGGT GGCTCTATCG ACCTGCAATG GACTCCATGG CATGTTTGAG 
GATGACACCT TTGTGTATAT GATAGAGCCG CTGGAACTGA CTGATGATGA GAAAAGCACA 
GGCCGACCAC ACATAATCCA GAAAACCTTG GCAGGACAGT ATTCTAAGCA GATGAAGAAT 
CTCAGCACAG ATGGCAGTGA CCAGTGGCCT TTGCTACCTG AATTACAATG GCTGAGAAGA 
AGGAAAAGAG CGGTCAATCC ATCTCGTGGT GTGTTTGAAG AAATGAAGTA TTTGGAGCTT 
ATGATTGTTA ATGATCACAA GACGTATAAG AAGCACCGCT CTTCTCACGC GCATACCAAC 
AACTTCGCAA AGTCTGTGGT CAACCTTGTA GATTCTATTT ACAAGGAACA GCTCAACACC 
AGGGTTGTCC TGGTGGCTGT CGAGACCTGG ACCGAGAAGG ATCACATTGA CATCACCATC 
AACCCCGTGC AGATGCTACA TGACTTCTCC AAGTACCGGC AGCGAATCAA ACAGCACGCT 
GACGCGGTCC ACCTCATCTC GCGCGTGACA TTCCATTATA AGAGAAGCAG TCTGAGTTAC 
TTTGGAGGCG TGTGTTCTCG AATAAGAGGG GTTGGTGTGA ATGAGTATGG TCTTCCAATG 
GCGGTGGCAC AAGTATTATC ACAGAGCCTG GCTCAAAACC TTGGAATCCA GTGGGAACCT 
TCGAGCAGGA AGCCAAAATG TGAATGCATA GAGTCCTGGG GCGGCTGCAT CATGGAAGAA 
ACAGGGGTGT CCCACTCTCG AAAGTTCTCA AAGTGCAGCA TTTTGGAGTA CAGAGACTTT 
TTACAGAGAG GTGGCGGAGC ATGTCTTTTC AATAGGCCAA CTAAGCTGTT TGAGCCCACG 
GAATGTGGAA ATGGATATGT GGAGGCCGGG GAGGAATGCG ACTGTGGTTT CCATGTGGAA 
TGCTATGGAG TTTGCTGTAA GAAGTGTTCG CTCTCCAATG GGGCCCACTG CAGTGACGGC 
CCCTGCTGTA ACAACACCTC ATGTCTTTTT CAGTCACGAG GGTATGAATG TCGGGATGCC 
GTAAACAGCT GTGATATCAC CGAGTACTGC ACTGGAGACT CTGGCCAGTG CCCACCGAAC 
CTCCATAAAC AAGATGGCTA TAGCTGCAAT CAAAATCAGG GTCGCTGCTA CAATGGCGAG 
TGCAAGACAA GGGACAATCA ATGCCAGTAC ATCTGGGGGA CAAAGGCTGC GGGGTCAGAC 
AAGTTCTGCT ATGAAAAGCT GAACACGGAA GGCACCGAGA AGGGCAATTG TGGAAAGGAT 
GGAGACCGGT GGATCCCGTG CAGCAAGCAT GATGTGTTCT GTGGATTTCT GCTTTGCACC 
AATCTTACCC GAGCTCCACG TATCGGTCAA CTTCAAGGAG AGATCATCCC GACTTCCTTC 
TATCATCAAG GCCGAGTGAT TGACTGCAGT GGTGCTCATG TAGTTTTAGA CGATGATACA 
GACGTGGGTT ACGTTGAAGA TGGGACTCCG TGTGGCCCCT CCATGATGTG CTTAGATCGG 
AAGTGCCTAC AGATTCAAGC CCTGAATATG AGCAGCTGCC CACTTGACTC AAGGGGTAAA 
GTCTGCTCCG GCCACGGGGT GTGTAGCAAC GAAGCCACCT GCATCTGTGA TTTCACTTGG 
GCAGGCACAG ACTGCAGCAT CCGGGATCCA GTTCGGAACC CCAACCCCCC TAAGGATGAA 
GGCCCTAAGG AAACGTCAAG AAGAGGAGAT TCGATCCCAC TCAGCAAGGC CCCATCTGAA 
TCGTCTGCAC TGGAGGAATG CCACCTTGCA CTGTTGGGTT CTGGGAATGA CATGTTTTCA 
GCCATGCTGC CGGAACTCTT AAGTCTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006496033.1
CDS	328..2817
Translation	MKPPGSISRRPTLTGCSLPGASCGPGRCPAGPVPARAPPCRLLLVLLLLPALATSSRPRARGAAAPSAPHWNETAEKTLGVLADEDNTLQQNSSSRNTSYSSAVQKEITLPSRLVYYINQDSESPYHVLDTKARHQQKHNKAVHLAQASFQIEAFGSKFILDLTLNNGLLSSDYVEIHYEDGKQMYSKGGEHCYYHGSIRGVKDSRVALSTCNGLHGMFEDDTFVYMIEPLELTDDEKSTGRPHIIQKTLAGQYSKQMKNLSTDGSDQWPLLPELQWLRRRKRAVNPSRGVFEEMKYLELMIVNDHKTYKKHRSSHAHTNNFAKSVVNLVDSIYKEQLNTRVVLVAVETWTEKDHIDITINPVQMLHDFSKYRQRIKQHADAVHLISRVTFHYKRSSLSYFGGVCSRIRGVGVNEYGLPMAVAQVLSQSLAQNLGIQWEPSSRKPKCECIESWGGCIMEETGVSHSRKFSKCSILEYRDFLQRGGGACLFNRPTKLFEPTECGNGYVEAGEECDCGFHVECYGVCCKKCSLSNGAHCSDGPCCNNTSCLFQSRGYECRDAVNSCDITEYCTGDSGQCPPNLHKQDGYSCNQNQGRCYNGECKTRDNQCQYIWGTKAAGSDKFCYEKLNTEGTEKGNCGKDGDRWIPCSKHDVFCGFLLCTNLTRAPRIGQLQGEIIPTSFYHQGRVIDCSGAHVVLDDDTDVGYVEDGTPCGPSMMCLDRKCLQIQALNMSSCPLDSRGKVCSGHGVCSNEATCICDFTWAGTDCSIRDPVRNPNPPKDEGPKETSRRGDSIPLSKAPSESSALEECHLALLGSGNDMFSAMLPELLSL

Target ORF information:

RefSeq Version	XM_006495970.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus a disintegrin and metallopeptidase domain 23 (Adam23), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006495970.3

ORF Insert Sequence:

ATGAAGCCGC CCGGCAGCAT CTCCCGGCGG CCGACCCTGA CGGGTTGCAG CCTTCCCGGC 
GCCTCCTGCG GCCCCGGCCG CTGCCCCGCC GGCCCGGTGC CGGCCCGCGC GCCGCCCTGC 
CGCCTGCTCC TCGTCCTTCT CCTGCTACCT GCGCTCGCCA CCTCATCCCG GCCCCGTGCC 
CGGGGGGCCG CTGCGCCCAG CGCTCCGCAC TGGAATGAAA CTGCAGAAAA AACCCTGGGA 
GTCCTGGCAG ATGAAGACAA CACATTGCAA CAAAATAGCA GCAGCAGAAA TACCAGCTAC 
AGCAGTGCAG TGCAAAAAGA AATCACACTG CCTTCAAGAC TGGTGTATTA CATCAACCAG 
GACTCAGAAA GCCCCTATCA TGTTCTTGAC ACAAAGGCCA GACACCAACA GAAACACAAT 
AAGGCTGTGC ATCTGGCCCA GGCAAGCTTC CAGATCGAAG CTTTCGGCTC CAAGTTCATT 
CTTGACCTCA CACTGAACAA TGGTTTGCTA TCTTCTGACT ACGTGGAGAT CCACTATGAA 
GACGGGAAGC AGATGTACTC TAAGGGTGGA GAGCACTGTT ACTACCACGG AAGCATCAGA 
GGCGTCAAGG ATTCCAGGGT GGCTCTATCG ACCTGCAATG GACTCCATGG CATGTTTGAG 
GATGACACCT TTGTGTATAT GATAGAGCCG CTGGAACTGA CTGATGATGA GAAAAGCACA 
GGCCGACCAC ACATAATCCA GAAAACCTTG GCAGGACAGT ATTCTAAGCA GATGAAGAAT 
CTCAGCACAG ATGGCAGTGA CCAGTGGCCT TTGCTACCTG AATTACAATG GCTGAGAAGA 
AGGAAAAGAG CGGTCAATCC ATCTCGTGGT GTGTTTGAAG AAATGAAGTA TTTGGAGCTT 
ATGATTGTTA ATGATCACAA GACGTATAAG AAGCACCGCT CTTCTCACGC GCATACCAAC 
AACTTCGCAA AGTCTGTGGT CAACCTTGTA GATTCTATTT ACAAGGAACA GCTCAACACC 
AGGGTTGTCC TGGTGGCTGT CGAGACCTGG ACCGAGAAGG ATCACATTGA CATCACCATC 
AACCCCGTGC AGATGCTACA TGACTTCTCC AAGTACCGGC AGCGAATCAA ACAGCACGCT 
GACGCGGTCC ACCTCATCTC GCGCGTGACA TTCCATTATA AGAGAAGCAG TCTGAGTTAC 
TTTGGAGGCG TGTGTTCTCG AATAAGAGGG GTTGGTGTGA ATGAGTATGG TCTTCCAATG 
GCGGTGGCAC AAGTATTATC ACAGAGCCTG GCTCAAAACC TTGGAATCCA GTGGGAACCT 
TCGAGCAGGA AGCCAAAATG TGAATGCATA GAGTCCTGGG GCGGCTGCAT CATGGAAGAA 
ACAGGGGTGT CCCACTCTCG AAAGTTCTCA AAGTGCAGCA TTTTGGAGTA CAGAGACTTT 
TTACAGAGAG GTGGCGGAGC ATGTCTTTTC AATAGGCCAA CTAAGCTGTT TGAGCCCACG 
GAATGTGGAA ATGGATATGT GGAGGCCGGG GAGGAATGCG ACTGTGGTTT CCATGTGGAA 
TGCTATGGAG TTTGCTGTAA GAAGTGTTCG CTCTCCAATG GGGCCCACTG CAGTGACGGC 
CCCTGCTGTA ACAACACCTC ATGTCTTTTT CAGTCACGAG GGTATGAATG TCGGGATGCC 
GTAAACAGCT GTGATATCAC CGAGTACTGC ACTGGAGACT CTGGCCAGTG CCCACCGAAC 
CTCCATAAAC AAGATGGCTA TAGCTGCAAT CAAAATCAGG GTCGCTGCTA CAATGGCGAG 
TGCAAGACAA GGGACAATCA ATGCCAGTAC ATCTGGGGGA CAAAGGCTGC GGGGTCAGAC 
AAGTTCTGCT ATGAAAAGCT GAACACGGAA GGCACCGAGA AGGGCAATTG TGGAAAGGAT 
GGAGACCGGT GGATCCCGTG CAGCAAGCAT GATGTGTTCT GTGGATTTCT GCTTTGCACC 
AATCTTACCC GAGCTCCACG TATCGGTCAA CTTCAAGGAG AGATCATCCC GACTTCCTTC 
TATCATCAAG GCCGAGTGAT TGACTGCAGT GGTGCTCATG TAGTTTTAGA CGATGATACA 
GACGTGGGTT ACGTTGAAGA TGGGACTCCG TGTGGCCCCT CCATGATGTG CTTAGATCGG 
AAGTGCCTAC AGATTCAAGC CCTGAATATG AGCAGCTGCC CACTTGACTC AAGGGGTAAA 
GTCTGCTCCG GCCACGGGGT GTGTAGCAAC GAAGCCACCT GCATCTGTGA TTTCACTTGG 
GCAGGCACAG ACTGCAGCAT CCGGGATCCA GTTCGGAACC CCAACCCCCC TAAGGATGAA 
GGCCCTAAGG AAACGTCAAG AAGAGGAGAT TCGATCCCAC TCAGCAAGGC CCCATCTGAA 
TCGTCTGCAC TGGAGGAATG CCACCTTGCA CTGTTGGGTT CTGGGAATGA CATGTTTTCA 
GCCATGCTGC CGGAACTCTT AAGTCTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dendritic cell expression of ADAM23 governs T cell proliferation and cytokine production through the ?(v)?(3) integrin receptor.
Journal of leukocyte biology100(5)855-864(2016 11)
Elizondo DM,Andargie TE,Marshall KM,Zariwala AM,Lipscomb MW

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes.
Biochimica et biophysica acta1854(7)827-33(2015 Jul)
Chen N,Koopmans F,Gordon A,Paliukhovich I,Klaassen RV,van der Schors RC,Peles E,Verhage M,Smit AB,Li KW

Functional phylogenetic analysis of LGI proteins identifies an interaction motif crucial for myelination.
Development (Cambridge, England)141(8)1749-56(2014 Apr)
Kegel L,Jaegle M,Driegen S,Aunin E,Leslie K,Fukata Y,Watanabe M,Fukata M,Meijer D

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Adam23 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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