C1qtnf5 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	C1qtnf5
Entrez Gene ID	235312
Full Name	C1q and tumor necrosis factor related protein 5
Synonyms	Ctrp5
General protein information	Preferred Names C1q and tumor necrosis factor related protein 5 Names complement C1q tumor necrosis factor-related protein 5
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9 A5.1\|9 24.62 cM
Summary	The protein encoded by this gene is a member of the C1q/tumor necrosis factor superfamily. This family member is a secretory protein that functions in eye development. Mutations in this gene are thought to underlie the pathophysiology of late-onset retinal degeneration (L-ORD) and early-onset long anterior zonules (LAZ). Bicistronic transcripts composed of the coding sequences for this gene (C1qtnf5) and the membrane-type frizzled-related protein gene (Mfrp) have been identified, and the resulting products can interact with each other. Co-transcription of C1qtnf5 and Mfrp has been observed in both human and mouse. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001040631.2	NP_001035721.1	complement C1q tumor necrosis factor-related protein 5 precursor
NM_001190319.1	NP_001177248.1	complement C1q tumor necrosis factor-related protein 5 precursor
NM_001190313.1	NP_001177242.1	complement C1q tumor necrosis factor-related protein 5 precursor
NM_001040632.2	NP_001035722.1	complement C1q tumor necrosis factor-related protein 5 precursor
NM_145613.4	NP_663588.2	complement C1q tumor necrosis factor-related protein 5 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	C1QTNF5	NP_056460.1
Canis lupus familiaris (dog)	C1QTNF5	XP_853180.3
Mus musculus (house mouse)	C1qtnf5	NP_001177242.1
	C1QTNF5	XP_001105035.2
Bos taurus (cattle)	C1QTNF5	NP_001092608.1
Rattus norvegicus (Norway rat)	C1qtnf5	NP_001012123.1
Danio rerio (zebrafish)	c1qtnf5	NP_001025124.1
Gallus gallus (chicken)	C1QTNF5	XP_001232467.2
Xenopus tropicalis (tropical clawed frog)	c1qtnf5	XP_002935065.2

Gene Ontology
Bibliography

Related articles in PubMed

Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
Sundberg JP, Dadras SS, Silva KA, Kennedy VE, Garland G, Murray SA, Sundberg BA, Schofield PN, Pratt CH
PloS one12(7)e0180682(2017)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Membrane frizzled-related protein is necessary for the normal development and maintenance of photoreceptor outer segments.
Won J, Smith RS, Peachey NS, Wu J, Hicks WL, Naggert JK, Nishina PM
Visual neuroscience25(4)563-74(2008 Jul-Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

pathological effects of S163R mutation expression in retinal pigment epithelium
Title: Pathological Effects of Mutant C1QTNF5 (S163R) Expression in Murine Retinal Pigment Epithelium.

Presence of rd8 (Crb1) mutation does not alter the ocular phenotype of late-onset retinal degeneration mouse model carrying the Ctrp5 mutation.
Title: Presence of rd8 mutation does not alter the ocular phenotype of late-onset retinal degeneration mouse model.

CTRP-5 is functionally involved in adipocyte biology.
Title: Regulation and function of C1Q/TNF-related protein-5 (CTRP-5) in the context of adipocyte biology.

Ets-2 play a key role in transcriptional regulation of CTRP5 in muscle cells.
Title: Ets-2 is involved in transcriptional regulation of C1qTNF-related protein 5 in muscle cells.

CTRP5, a secretory and membrane-associated protein, is localized to the lateral and apical membranes of the RPE and CB. Impaired secretion of the mutant protein may underlie the pathophysiology of long anterior zonules and late-onset retinal degeneration.
Title: CTRP5 is a membrane-associated and secretory protein in the RPE and ciliary body and the S163R mutation of CTRP5 impairs its secretion.

The following C1qtnf5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the C1qtnf5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu00840	NM_145613.4 Latest version!	Mus musculus C1q and tumor necrosis factor related protein 5 (C1qtnf5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu00840	NM_001040632.2 Latest version!	Mus musculus C1q and tumor necrosis factor related protein 5 (C1qtnf5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu00840	NM_001190313.1 Latest version!	Mus musculus C1q and tumor necrosis factor related protein 5 (C1qtnf5), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu00840	NM_001040631.2 Latest version!	Mus musculus C1q and tumor necrosis factor related protein 5 (C1qtnf5), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu00840	NM_001190319.1 Latest version!	Mus musculus C1q and tumor necrosis factor related protein 5 (C1qtnf5), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

C1qtnf5 ( NM_001040631.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001035721.1 Mus musculus C1q and tumor necrosis factor related protein 5 (C1qtnf5), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu00840
Clone ID Related Accession (Same CDS sequence)	NM_001040631.2 , NM_001190319.1 , NM_001190313.1 , NM_001040632.2 , NM_145613.4
Accession Version	NM_001040631.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 732bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-21
Organism	Mus musculus(house mouse)
Product	complement C1q tumor necrosis factor-related protein 5 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC148328.3, DQ002398.1, BE861753.1 and AW490764.1. On Jun 15, 2010 this sequence version replaced NM_001040631.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. This variant is represented as monocistronic and may not be 5'-complete; it is unclear if it exists in bicistronic form with the Mfrp ORF, or if it is derived from an internal promoter. Variants 1-5 encode the same C1qtnf5 protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ002398.1, BI688017.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGCCAC TTCTTGCCCT TCTGCTTCTG GGTCTGGTGT CAGGCTCTCC TCCTCTGGAC 
GACAACAAGA TCCCCAGCCT GTGTCCCGGG CAGCCCGGCC TTCCAGGCAC ACCAGGTCAC 
CATGGCAGCC AAGGCCTGCC TGGCCGTGAC GGCCGTGATG GCCGCGACGG TGCACCCGGA 
GCTCCGGGAG AGAAAGGCGA GGGCGGGAGA CCGGGACTAC CTGGCCCACG TGGGGAGCCC 
GGGCCGCGTG GAGAGGCAGG GCCCATGGGG GCTATCGGGC CTGCGGGGGA GTGCTCGGTA 
CCCCCACGAT CAGCCTTCAG TGCCAAGCGA TCCGAGAGCC GGGTACCTCC GCCAGCCGAC 
ACACCCCTAC CTTTCGACCG TGTGCTGCTA AATGAGCAGG GCCATTACGA CCCCACTACT 
GGCAAGTTCA CCTGCCAAGT GCCTGGCGTC TACTACTTTG CTGTGCACGC CACTGTCTAC 
CGGGCCAGCT TGCAGTTTGA TCTTGTCAAA AACGGGCAGT CCATCGCCTC TTTCTTCCAG 
TATTTTGGGG GGTGGCCCAA GCCAGCCTCG CTCTCAGGGG GTGCGATGGT AAGGCTAGAA 
CCTGAGGACC AGGTGTGGGT GCAGGTGGGC GTGGGTGATT ACATTGGCAT CTATGCCAGC 
ATCAAGACAG ACAGTACCTT CTCTGGATTT CTCGTCTATT CTGACTGGCA CAGCTCCCCA 
GTCTTCGCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001035721.1
CDS	153..884
Translation	MRPLLALLLLGLVSGSPPLDDNKIPSLCPGQPGLPGTPGHHGSQGLPGRDGRDGRDGAPGAPGEKGEGGRPGLPGPRGEPGPRGEAGPMGAIGPAGECSVPPRSAFSAKRSESRVPPPADTPLPFDRVLLNEQGHYDPTTGKFTCQVPGVYYFAVHATVYRASLQFDLVKNGQSIASFFQYFGGWPKPASLSGGAMVRLEPEDQVWVQVGVGDYIGIYASIKTDSTFSGFLVYSDWHSSPVFA

Target ORF information:

RefSeq Version	NM_001040631.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus C1q and tumor necrosis factor related protein 5 (C1qtnf5), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001040631.2

ORF Insert Sequence:

ATGAGGCCAC TTCTTGCCCT TCTGCTTCTG GGTCTGGTGT CAGGCTCTCC TCCTCTGGAC 
GACAACAAGA TCCCCAGCCT GTGTCCCGGG CAGCCCGGCC TTCCAGGCAC ACCAGGTCAC 
CATGGCAGCC AAGGCCTGCC TGGCCGTGAC GGCCGTGATG GCCGCGACGG TGCACCCGGA 
GCTCCGGGAG AGAAAGGCGA GGGCGGGAGA CCGGGACTAC CTGGCCCACG TGGGGAGCCC 
GGGCCGCGTG GAGAGGCAGG GCCCATGGGG GCTATCGGGC CTGCGGGGGA GTGCTCGGTA 
CCCCCACGAT CAGCCTTCAG TGCCAAGCGA TCCGAGAGCC GGGTACCTCC GCCAGCCGAC 
ACACCCCTAC CTTTCGACCG TGTGCTGCTA AATGAGCAGG GCCATTACGA CCCCACTACT 
GGCAAGTTCA CCTGCCAAGT GCCTGGCGTC TACTACTTTG CTGTGCACGC CACTGTCTAC 
CGGGCCAGCT TGCAGTTTGA TCTTGTCAAA AACGGGCAGT CCATCGCCTC TTTCTTCCAG 
TATTTTGGGG GGTGGCCCAA GCCAGCCTCG CTCTCAGGGG GTGCGATGGT AAGGCTAGAA 
CCTGAGGACC AGGTGTGGGT GCAGGTGGGC GTGGGTGATT ACATTGGCAT CTATGCCAGC 
ATCAAGACAG ACAGTACCTT CTCTGGATTT CTCGTCTATT CTGACTGGCA CAGCTCCCCA 
GTCTTCGCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C1qtnf5 ( NM_001190319.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001177248.1 Mus musculus C1q and tumor necrosis factor related protein 5 (C1qtnf5), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OMu00840
Clone ID Related Accession (Same CDS sequence)	NM_001040631.2 , NM_001190319.1 , NM_001190313.1 , NM_001040632.2 , NM_145613.4
Accession Version	NM_001190319.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 732bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-21
Organism	Mus musculus(house mouse)
Product	complement C1q tumor necrosis factor-related protein 5 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CK626457.1, BE861753.1 and AW490764.1. Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. This variant is represented as monocistronic and may not be 5'-complete; it is unclear if it exists in bicistronic form with the Mfrp ORF, or if it is derived from an internal promoter. Variants 1-5 encode the same C1qtnf5 protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CK626457.1, BY254212.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGCCAC TTCTTGCCCT TCTGCTTCTG GGTCTGGTGT CAGGCTCTCC TCCTCTGGAC 
GACAACAAGA TCCCCAGCCT GTGTCCCGGG CAGCCCGGCC TTCCAGGCAC ACCAGGTCAC 
CATGGCAGCC AAGGCCTGCC TGGCCGTGAC GGCCGTGATG GCCGCGACGG TGCACCCGGA 
GCTCCGGGAG AGAAAGGCGA GGGCGGGAGA CCGGGACTAC CTGGCCCACG TGGGGAGCCC 
GGGCCGCGTG GAGAGGCAGG GCCCATGGGG GCTATCGGGC CTGCGGGGGA GTGCTCGGTA 
CCCCCACGAT CAGCCTTCAG TGCCAAGCGA TCCGAGAGCC GGGTACCTCC GCCAGCCGAC 
ACACCCCTAC CTTTCGACCG TGTGCTGCTA AATGAGCAGG GCCATTACGA CCCCACTACT 
GGCAAGTTCA CCTGCCAAGT GCCTGGCGTC TACTACTTTG CTGTGCACGC CACTGTCTAC 
CGGGCCAGCT TGCAGTTTGA TCTTGTCAAA AACGGGCAGT CCATCGCCTC TTTCTTCCAG 
TATTTTGGGG GGTGGCCCAA GCCAGCCTCG CTCTCAGGGG GTGCGATGGT AAGGCTAGAA 
CCTGAGGACC AGGTGTGGGT GCAGGTGGGC GTGGGTGATT ACATTGGCAT CTATGCCAGC 
ATCAAGACAG ACAGTACCTT CTCTGGATTT CTCGTCTATT CTGACTGGCA CAGCTCCCCA 
GTCTTCGCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001177248.1
CDS	228..959
Translation	MRPLLALLLLGLVSGSPPLDDNKIPSLCPGQPGLPGTPGHHGSQGLPGRDGRDGRDGAPGAPGEKGEGGRPGLPGPRGEPGPRGEAGPMGAIGPAGECSVPPRSAFSAKRSESRVPPPADTPLPFDRVLLNEQGHYDPTTGKFTCQVPGVYYFAVHATVYRASLQFDLVKNGQSIASFFQYFGGWPKPASLSGGAMVRLEPEDQVWVQVGVGDYIGIYASIKTDSTFSGFLVYSDWHSSPVFA

Target ORF information:

RefSeq Version	NM_001190319.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus C1q and tumor necrosis factor related protein 5 (C1qtnf5), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001190319.1

ORF Insert Sequence:

ATGAGGCCAC TTCTTGCCCT TCTGCTTCTG GGTCTGGTGT CAGGCTCTCC TCCTCTGGAC 
GACAACAAGA TCCCCAGCCT GTGTCCCGGG CAGCCCGGCC TTCCAGGCAC ACCAGGTCAC 
CATGGCAGCC AAGGCCTGCC TGGCCGTGAC GGCCGTGATG GCCGCGACGG TGCACCCGGA 
GCTCCGGGAG AGAAAGGCGA GGGCGGGAGA CCGGGACTAC CTGGCCCACG TGGGGAGCCC 
GGGCCGCGTG GAGAGGCAGG GCCCATGGGG GCTATCGGGC CTGCGGGGGA GTGCTCGGTA 
CCCCCACGAT CAGCCTTCAG TGCCAAGCGA TCCGAGAGCC GGGTACCTCC GCCAGCCGAC 
ACACCCCTAC CTTTCGACCG TGTGCTGCTA AATGAGCAGG GCCATTACGA CCCCACTACT 
GGCAAGTTCA CCTGCCAAGT GCCTGGCGTC TACTACTTTG CTGTGCACGC CACTGTCTAC 
CGGGCCAGCT TGCAGTTTGA TCTTGTCAAA AACGGGCAGT CCATCGCCTC TTTCTTCCAG 
TATTTTGGGG GGTGGCCCAA GCCAGCCTCG CTCTCAGGGG GTGCGATGGT AAGGCTAGAA 
CCTGAGGACC AGGTGTGGGT GCAGGTGGGC GTGGGTGATT ACATTGGCAT CTATGCCAGC 
ATCAAGACAG ACAGTACCTT CTCTGGATTT CTCGTCTATT CTGACTGGCA CAGCTCCCCA 
GTCTTCGCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C1qtnf5 ( NM_001190313.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001177242.1 Mus musculus C1q and tumor necrosis factor related protein 5 (C1qtnf5), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OMu00840
Clone ID Related Accession (Same CDS sequence)	NM_001040631.2 , NM_001190319.1 , NM_001190313.1 , NM_001040632.2 , NM_145613.4
Accession Version	NM_001190313.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 732bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-21
Organism	Mus musculus(house mouse)
Product	complement C1q tumor necrosis factor-related protein 5 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK053629.1, AC148328.3 and AF469650.1. Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. This variant is a bicistronic transcript that can encode the C1qtnf5 and Mfrp products; the C1qtnf5 protein is represented in this RefSeq. Variants 1-5 encode the same C1qtnf5 protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK053629.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## bicistronic transcript :: PMID: 12140190 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGGCCAC TTCTTGCCCT TCTGCTTCTG GGTCTGGTGT CAGGCTCTCC TCCTCTGGAC 
GACAACAAGA TCCCCAGCCT GTGTCCCGGG CAGCCCGGCC TTCCAGGCAC ACCAGGTCAC 
CATGGCAGCC AAGGCCTGCC TGGCCGTGAC GGCCGTGATG GCCGCGACGG TGCACCCGGA 
GCTCCGGGAG AGAAAGGCGA GGGCGGGAGA CCGGGACTAC CTGGCCCACG TGGGGAGCCC 
GGGCCGCGTG GAGAGGCAGG GCCCATGGGG GCTATCGGGC CTGCGGGGGA GTGCTCGGTA 
CCCCCACGAT CAGCCTTCAG TGCCAAGCGA TCCGAGAGCC GGGTACCTCC GCCAGCCGAC 
ACACCCCTAC CTTTCGACCG TGTGCTGCTA AATGAGCAGG GCCATTACGA CCCCACTACT 
GGCAAGTTCA CCTGCCAAGT GCCTGGCGTC TACTACTTTG CTGTGCACGC CACTGTCTAC 
CGGGCCAGCT TGCAGTTTGA TCTTGTCAAA AACGGGCAGT CCATCGCCTC TTTCTTCCAG 
TATTTTGGGG GGTGGCCCAA GCCAGCCTCG CTCTCAGGGG GTGCGATGGT AAGGCTAGAA 
CCTGAGGACC AGGTGTGGGT GCAGGTGGGC GTGGGTGATT ACATTGGCAT CTATGCCAGC 
ATCAAGACAG ACAGTACCTT CTCTGGATTT CTCGTCTATT CTGACTGGCA CAGCTCCCCA 
GTCTTCGCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001177242.1
CDS	3151..3882
Translation	MRPLLALLLLGLVSGSPPLDDNKIPSLCPGQPGLPGTPGHHGSQGLPGRDGRDGRDGAPGAPGEKGEGGRPGLPGPRGEPGPRGEAGPMGAIGPAGECSVPPRSAFSAKRSESRVPPPADTPLPFDRVLLNEQGHYDPTTGKFTCQVPGVYYFAVHATVYRASLQFDLVKNGQSIASFFQYFGGWPKPASLSGGAMVRLEPEDQVWVQVGVGDYIGIYASIKTDSTFSGFLVYSDWHSSPVFA

Target ORF information:

RefSeq Version	NM_001190313.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus C1q and tumor necrosis factor related protein 5 (C1qtnf5), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001190313.1

ORF Insert Sequence:

ATGAGGCCAC TTCTTGCCCT TCTGCTTCTG GGTCTGGTGT CAGGCTCTCC TCCTCTGGAC 
GACAACAAGA TCCCCAGCCT GTGTCCCGGG CAGCCCGGCC TTCCAGGCAC ACCAGGTCAC 
CATGGCAGCC AAGGCCTGCC TGGCCGTGAC GGCCGTGATG GCCGCGACGG TGCACCCGGA 
GCTCCGGGAG AGAAAGGCGA GGGCGGGAGA CCGGGACTAC CTGGCCCACG TGGGGAGCCC 
GGGCCGCGTG GAGAGGCAGG GCCCATGGGG GCTATCGGGC CTGCGGGGGA GTGCTCGGTA 
CCCCCACGAT CAGCCTTCAG TGCCAAGCGA TCCGAGAGCC GGGTACCTCC GCCAGCCGAC 
ACACCCCTAC CTTTCGACCG TGTGCTGCTA AATGAGCAGG GCCATTACGA CCCCACTACT 
GGCAAGTTCA CCTGCCAAGT GCCTGGCGTC TACTACTTTG CTGTGCACGC CACTGTCTAC 
CGGGCCAGCT TGCAGTTTGA TCTTGTCAAA AACGGGCAGT CCATCGCCTC TTTCTTCCAG 
TATTTTGGGG GGTGGCCCAA GCCAGCCTCG CTCTCAGGGG GTGCGATGGT AAGGCTAGAA 
CCTGAGGACC AGGTGTGGGT GCAGGTGGGC GTGGGTGATT ACATTGGCAT CTATGCCAGC 
ATCAAGACAG ACAGTACCTT CTCTGGATTT CTCGTCTATT CTGACTGGCA CAGCTCCCCA 
GTCTTCGCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C1qtnf5 ( NM_001040632.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001035722.1 Mus musculus C1q and tumor necrosis factor related protein 5 (C1qtnf5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu00840
Clone ID Related Accession (Same CDS sequence)	NM_001040631.2 , NM_001190319.1 , NM_001190313.1 , NM_001040632.2 , NM_145613.4
Accession Version	NM_001040632.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 732bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-21
Organism	Mus musculus(house mouse)
Product	complement C1q tumor necrosis factor-related protein 5 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC148328.3, CX201109.1, BE861753.1 and AW490764.1. On Jun 15, 2010 this sequence version replaced NM_001040632.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. This variant is represented as monocistronic and may not be 5'-complete; it is unclear if it exists in bicistronic form with the Mfrp ORF, or if it is derived from an internal promoter. Variants 1-5 encode the same C1qtnf5 protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CK793040.1, BF540263.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGCCAC TTCTTGCCCT TCTGCTTCTG GGTCTGGTGT CAGGCTCTCC TCCTCTGGAC 
GACAACAAGA TCCCCAGCCT GTGTCCCGGG CAGCCCGGCC TTCCAGGCAC ACCAGGTCAC 
CATGGCAGCC AAGGCCTGCC TGGCCGTGAC GGCCGTGATG GCCGCGACGG TGCACCCGGA 
GCTCCGGGAG AGAAAGGCGA GGGCGGGAGA CCGGGACTAC CTGGCCCACG TGGGGAGCCC 
GGGCCGCGTG GAGAGGCAGG GCCCATGGGG GCTATCGGGC CTGCGGGGGA GTGCTCGGTA 
CCCCCACGAT CAGCCTTCAG TGCCAAGCGA TCCGAGAGCC GGGTACCTCC GCCAGCCGAC 
ACACCCCTAC CTTTCGACCG TGTGCTGCTA AATGAGCAGG GCCATTACGA CCCCACTACT 
GGCAAGTTCA CCTGCCAAGT GCCTGGCGTC TACTACTTTG CTGTGCACGC CACTGTCTAC 
CGGGCCAGCT TGCAGTTTGA TCTTGTCAAA AACGGGCAGT CCATCGCCTC TTTCTTCCAG 
TATTTTGGGG GGTGGCCCAA GCCAGCCTCG CTCTCAGGGG GTGCGATGGT AAGGCTAGAA 
CCTGAGGACC AGGTGTGGGT GCAGGTGGGC GTGGGTGATT ACATTGGCAT CTATGCCAGC 
ATCAAGACAG ACAGTACCTT CTCTGGATTT CTCGTCTATT CTGACTGGCA CAGCTCCCCA 
GTCTTCGCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001035722.1
CDS	244..975
Translation	MRPLLALLLLGLVSGSPPLDDNKIPSLCPGQPGLPGTPGHHGSQGLPGRDGRDGRDGAPGAPGEKGEGGRPGLPGPRGEPGPRGEAGPMGAIGPAGECSVPPRSAFSAKRSESRVPPPADTPLPFDRVLLNEQGHYDPTTGKFTCQVPGVYYFAVHATVYRASLQFDLVKNGQSIASFFQYFGGWPKPASLSGGAMVRLEPEDQVWVQVGVGDYIGIYASIKTDSTFSGFLVYSDWHSSPVFA

Target ORF information:

RefSeq Version	NM_001040632.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus C1q and tumor necrosis factor related protein 5 (C1qtnf5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001040632.2

ORF Insert Sequence:

ATGAGGCCAC TTCTTGCCCT TCTGCTTCTG GGTCTGGTGT CAGGCTCTCC TCCTCTGGAC 
GACAACAAGA TCCCCAGCCT GTGTCCCGGG CAGCCCGGCC TTCCAGGCAC ACCAGGTCAC 
CATGGCAGCC AAGGCCTGCC TGGCCGTGAC GGCCGTGATG GCCGCGACGG TGCACCCGGA 
GCTCCGGGAG AGAAAGGCGA GGGCGGGAGA CCGGGACTAC CTGGCCCACG TGGGGAGCCC 
GGGCCGCGTG GAGAGGCAGG GCCCATGGGG GCTATCGGGC CTGCGGGGGA GTGCTCGGTA 
CCCCCACGAT CAGCCTTCAG TGCCAAGCGA TCCGAGAGCC GGGTACCTCC GCCAGCCGAC 
ACACCCCTAC CTTTCGACCG TGTGCTGCTA AATGAGCAGG GCCATTACGA CCCCACTACT 
GGCAAGTTCA CCTGCCAAGT GCCTGGCGTC TACTACTTTG CTGTGCACGC CACTGTCTAC 
CGGGCCAGCT TGCAGTTTGA TCTTGTCAAA AACGGGCAGT CCATCGCCTC TTTCTTCCAG 
TATTTTGGGG GGTGGCCCAA GCCAGCCTCG CTCTCAGGGG GTGCGATGGT AAGGCTAGAA 
CCTGAGGACC AGGTGTGGGT GCAGGTGGGC GTGGGTGATT ACATTGGCAT CTATGCCAGC 
ATCAAGACAG ACAGTACCTT CTCTGGATTT CTCGTCTATT CTGACTGGCA CAGCTCCCCA 
GTCTTCGCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C1qtnf5 ( NM_145613.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_663588.2 Mus musculus C1q and tumor necrosis factor related protein 5 (C1qtnf5), transcript variant 1, mRNA.

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CloneID	OMu00840
Clone ID Related Accession (Same CDS sequence)	NM_001040631.2 , NM_001190319.1 , NM_001190313.1 , NM_001040632.2 , NM_145613.4
Accession Version	NM_145613.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 732bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-21
Organism	Mus musculus(house mouse)
Product	complement C1q tumor necrosis factor-related protein 5 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK053629.1 and AF469650.1. On Jun 15, 2010 this sequence version replaced NM_145613.3. Transcript Variant: This variant (1) represents the longest transcript. This variant is a bicistronic transcript that can encode the C1qtnf5 and Mfrp products; the C1qtnf5 protein is represented in this RefSeq. Variants 1-5 encode the same C1qtnf5 protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF469650.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## bicistronic transcript :: PMID: 12140190 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGGCCAC TTCTTGCCCT TCTGCTTCTG GGTCTGGTGT CAGGCTCTCC TCCTCTGGAC 
GACAACAAGA TCCCCAGCCT GTGTCCCGGG CAGCCCGGCC TTCCAGGCAC ACCAGGTCAC 
CATGGCAGCC AAGGCCTGCC TGGCCGTGAC GGCCGTGATG GCCGCGACGG TGCACCCGGA 
GCTCCGGGAG AGAAAGGCGA GGGCGGGAGA CCGGGACTAC CTGGCCCACG TGGGGAGCCC 
GGGCCGCGTG GAGAGGCAGG GCCCATGGGG GCTATCGGGC CTGCGGGGGA GTGCTCGGTA 
CCCCCACGAT CAGCCTTCAG TGCCAAGCGA TCCGAGAGCC GGGTACCTCC GCCAGCCGAC 
ACACCCCTAC CTTTCGACCG TGTGCTGCTA AATGAGCAGG GCCATTACGA CCCCACTACT 
GGCAAGTTCA CCTGCCAAGT GCCTGGCGTC TACTACTTTG CTGTGCACGC CACTGTCTAC 
CGGGCCAGCT TGCAGTTTGA TCTTGTCAAA AACGGGCAGT CCATCGCCTC TTTCTTCCAG 
TATTTTGGGG GGTGGCCCAA GCCAGCCTCG CTCTCAGGGG GTGCGATGGT AAGGCTAGAA 
CCTGAGGACC AGGTGTGGGT GCAGGTGGGC GTGGGTGATT ACATTGGCAT CTATGCCAGC 
ATCAAGACAG ACAGTACCTT CTCTGGATTT CTCGTCTATT CTGACTGGCA CAGCTCCCCA 
GTCTTCGCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_663588.2
CDS	3169..3900
Translation	MRPLLALLLLGLVSGSPPLDDNKIPSLCPGQPGLPGTPGHHGSQGLPGRDGRDGRDGAPGAPGEKGEGGRPGLPGPRGEPGPRGEAGPMGAIGPAGECSVPPRSAFSAKRSESRVPPPADTPLPFDRVLLNEQGHYDPTTGKFTCQVPGVYYFAVHATVYRASLQFDLVKNGQSIASFFQYFGGWPKPASLSGGAMVRLEPEDQVWVQVGVGDYIGIYASIKTDSTFSGFLVYSDWHSSPVFA

Target ORF information:

RefSeq Version	NM_145613.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus C1q and tumor necrosis factor related protein 5 (C1qtnf5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145613.4

ORF Insert Sequence:

ATGAGGCCAC TTCTTGCCCT TCTGCTTCTG GGTCTGGTGT CAGGCTCTCC TCCTCTGGAC 
GACAACAAGA TCCCCAGCCT GTGTCCCGGG CAGCCCGGCC TTCCAGGCAC ACCAGGTCAC 
CATGGCAGCC AAGGCCTGCC TGGCCGTGAC GGCCGTGATG GCCGCGACGG TGCACCCGGA 
GCTCCGGGAG AGAAAGGCGA GGGCGGGAGA CCGGGACTAC CTGGCCCACG TGGGGAGCCC 
GGGCCGCGTG GAGAGGCAGG GCCCATGGGG GCTATCGGGC CTGCGGGGGA GTGCTCGGTA 
CCCCCACGAT CAGCCTTCAG TGCCAAGCGA TCCGAGAGCC GGGTACCTCC GCCAGCCGAC 
ACACCCCTAC CTTTCGACCG TGTGCTGCTA AATGAGCAGG GCCATTACGA CCCCACTACT 
GGCAAGTTCA CCTGCCAAGT GCCTGGCGTC TACTACTTTG CTGTGCACGC CACTGTCTAC 
CGGGCCAGCT TGCAGTTTGA TCTTGTCAAA AACGGGCAGT CCATCGCCTC TTTCTTCCAG 
TATTTTGGGG GGTGGCCCAA GCCAGCCTCG CTCTCAGGGG GTGCGATGGT AAGGCTAGAA 
CCTGAGGACC AGGTGTGGGT GCAGGTGGGC GTGGGTGATT ACATTGGCAT CTATGCCAGC 
ATCAAGACAG ACAGTACCTT CTCTGGATTT CTCGTCTATT CTGACTGGCA CAGCTCCCCA 
GTCTTCGCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
PloS one12(7)e0180682(2017)
Sundberg JP,Dadras SS,Silva KA,Kennedy VE,Garland G,Murray SA,Sundberg BA,Schofield PN,Pratt CH

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Membrane frizzled-related protein is necessary for the normal development and maintenance of photoreceptor outer segments.
Visual neuroscience25(4)563-74(2008 Jul-Aug)
Won J,Smith RS,Peachey NS,Wu J,Hicks WL,Naggert JK,Nishina PM

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C1qtnf5 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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