Lrfn4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lrfn4
Entrez Gene ID	225875
Full Name	leucine rich repeat and fibronectin type III domain containing 4
Synonyms	BC023156,Salm3
General protein information	Preferred Names leucine rich repeat and fibronectin type III domain containing 4 Names leucine-rich repeat and fibronectin type-III domain-containing protein 4 synaptic adhesion-like molecule 3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 19 Map Location: 19\|19 A

mRNA and Protein(s)

mRNA	Protein	Name
NM_153388.4	NP_700437.2	leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor
XM_017318142.2	XP_017173631.1	leucine-rich repeat and fibronectin type-III domain-containing protein 4 isoform X1
XM_017318142.1	XP_017173631.1	leucine-rich repeat and fibronectin type-III domain-containing protein 4 isoform X1

Pathways from BioSystems

Homologies

	LRFN4	XP_001107879.1
Canis lupus familiaris (dog)	LRFN4	XP_852214.1
Xenopus tropicalis (tropical clawed frog)	lrfn2	XP_004913581.1
Bos taurus (cattle)	LRFN4	NP_001193183.1
Danio rerio (zebrafish)	lrfn4b	XP_005166600.1
Homo sapiens (human)	LRFN4	NP_076941.2
Mus musculus (house mouse)	Lrfn4	NP_700437.2
Rattus norvegicus (Norway rat)	Lrfn4	NP_001102978.1
Danio rerio (zebrafish)	LOC101882983	XP_005161420.1

Gene Ontology
Bibliography

Related articles in PubMed

SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3-LAR adhesion.
Lie E, Ko JS, Choi SY, Roh JD, Cho YS, Noh R, Kim D, Li Y, Kang H, Choi TY, Nam J, Mah W, Lee D, Lee SG, Kim HM, Kim H, Choi SY, Um JW, Kang MG, Bae YC, Ko J, Kim E
Nature communications712328(2016 Aug)

Splicing-Dependent Trans-synaptic SALM3-LAR-RPTP Interactions Regulate Excitatory Synapse Development and Locomotion.
Li Y, Zhang P, Choi TY, Park SK, Park H, Lee EJ, Lee D, Roh JD, Mah W, Kim R, Kim Y, Kwon H, Bae YC, Choi SY, Craig AM, Kim E
Cell reports12(10)1618-30(2015 Sep)

miR-15b/16-2 deletion promotes B-cell malignancies.
Lovat F, Fassan M, Gasparini P, Rizzotto L, Cascione L, Pizzi M, Vicentini C, Balatti V, Palmieri D, Costinean S, Croce CM
Proceedings of the National Academy of Sciences of the United States of America112(37)11636-41(2015 Sep)

The SALM/Lrfn family of leucine-rich repeat-containing cell adhesion molecules.
Nam J, Mah W, Kim E
Seminars in cell & developmental biology22(5)492-8(2011 Jul)

Selected SALM (synaptic adhesion-like molecule) family proteins regulate synapse formation.
Mah W, Ko J, Nam J, Han K, Chung WS, Kim E
The Journal of neuroscience : the official journal of the Society for Neuroscience30(16)5559-68(2010 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Expression of SALM family proteins SALM3 and SALM5 in nonneural and neural cells induces both excitatory and inhibitory presynaptic differentiation in contacting axons.
Title: Selected SALM (synaptic adhesion-like molecule) family proteins regulate synapse formation.

Data show that the C-terminal PDZ binding domains of synaptic adhesion-like molecules (SALMs)1-3 are required for neurite outgrowth, and that the N-termini of SALMs 2 and 4 are alsoinvolved in neurite outgrowth.
Title: Synaptic adhesion-like molecules (SALMs) promote neurite outgrowth.

The following Lrfn4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lrfn4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu02376	NM_153388.4 Latest version!	Mus musculus leucine rich repeat and fibronectin type III domain containing 4 (Lrfn4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OMu02376	XM_017318142.2 Latest version!	Mus musculus leucine rich repeat and fibronectin type III domain containing 4 (Lrfn4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OMu02376	XM_017318142.1	Mus musculus leucine rich repeat and fibronectin type III domain containing 4 (Lrfn4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lrfn4 ( NM_153388.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_700437.2 Mus musculus leucine rich repeat and fibronectin type III domain containing 4 (Lrfn4), mRNA.

Price & Availability↑

CloneID	OMu02376
Clone ID Related Accession (Same CDS sequence)	NM_153388.4 , XM_017318142.2 , XM_017318142.1
Accession Version	NM_153388.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1911bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CA752061.1, AK163603.1 and AI415633.1. On Jul 8, 2009 this sequence version replaced NM_153388.3. ##Evidence-Data-START## Transcript exon combination :: AK163603.1, BC023156.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCCGC CGCTCCTATT GCTGCTGCTG GCCAGTGGAG CCGCTGCTTG CCCGCTACCC 
TGTGTGTGCC AGAACCTGTC GGAGTCACTC AGCACCCTTT GTGCCCACCG AGGCCTGCTG 
TTTGTGCCAC CCAACGTGGA CAGGCGCACA GTTGAACTGC GCCTGGCCGA CAACTTCATC 
CAGGCCCTGG GACCACCTGA CTTCCGCAAC ATGACAGGGC TGGTGGACCT AACATTGTCT 
CGAAATGCCA TCACCCGCAT TGGGGCTCGC TCCTTTGGGG ACCTGGAGAG CCTGCGCTCC 
TTGCACCTGG ATGGCAACAG GCTGGTGGAG CTGGGCAGCA GCAGCCTACG GGGGCCTGTC 
AACCTCCAGC ATCTCATTCT CAGTGGCAAT CAACTGGGCC GCATCGCCCC CGGGGCCTTC 
GACGACTTCC TTGACAGTCT CGAGGACCTG GATGTGTCCT ATAACAACCT CCGGCAGGTT 
CCCTGGGCTG GCATAGGCTC CATGCCTGCC CTGCATACCC TGAACCTGGA CCATAACCTC 
ATCGATGCAC TACCCCCAGG TGTCTTTGCT CAGCTCAGCC AGCTCTCCCG CCTTGACCTC 
ACCTCCAACC GCCTGGCCAC CCTGGCACCT GATCCACTCT TCTCCCGAGG CCGGGATGCT 
GAGGCCTCAC CTTCTCCCCT GGTGCTGAGT TTCAGCGGGA ACCCACTGCA CTGCAACTGT 
GAGCTGCTGT GGCTGCGGCG GCTGGCCCGG CCCGATGACC TGGAAACCTG CGCTTCTCCA 
CCAACCCTGG CAGGCCGCTA CTTCTGGGCA GTGCCTGAGG GAGAGTTCTC CTGTGAGCCT 
CCGCTGATTG CCCGGCACAC ACAGCGCCTG TGGGTGCTAG AGGGCCAGCG GGCCACCCTA 
CGGTGCAGGG CCCTTGGTGA CCCTGTACCT ACCATGCACT GGGTTGGCCC TGATGACAGG 
CTGGTTGGCA ACTCTTCTCG AGCCTGGGCT TTCCCCAATG GGACCCTAGA GATTGGGGTG 
ACGGGCGCTG GAGATGCAGG AGCCTATACC TGCATTGCCA CCAACCCTGC TGGTGAGGCC 
ACAGCCCGAG TGGAGCTCCG GGTACTGGCC TTGCCCCATG GTGGGAACAC CAGTGCTGAG 
GGGGGCCGTC CTGGGCCTTC GGACATTGCT GCTTCTGCTA GAACTGCTGC CGAAGGCGAG 
GGAACTTTAG AATCTGAACC AGCAGTGCAA GTGACGGAGG TGACTGCCAC CTCTGGCCTG 
GTGAGCTGGG GCCTGGGGCG GCCAGCTGAC CCAGTGTGGA TGTTCCAAAT CCAGTACAAC 
AGCAGCGAGG ATGAGACCCT CATCTACCGG ATTGTACCAG CCTCCAGCCA CCACTTCCTG 
CTGAAGCACC TGGTTCCCGG TGCTGACTAC GACCTCTGCC TGCTGGCCCT GTCACCTGCT 
GCTGGGCCCT CCGACCTCAC GGCCACTAGA CTGCTGGGCT GTGCCCACTT CTCTACGCTA 
CCAGCCACCC CCCTGTGCCA TGCCCTACAG GCCCATGTGC TGGGCGGGAC CCTGACTGTG 
GCAGTGGGGG GCGTCCTAGT GGCTGCCTTA CTGGTCTTCA CTGTGGCCTT GCTGGTTCGG 
GGCCGGGGAG CTGGGAATGG CCGCCTCCCA CTCAAACTCA GCCATGTCCA ATCCCAGACC 
AATGGTGGCA CCAGCCCCAT GCCCAAGAGC CACCCACCAC GGAGCCCTCC ACCCCGTCCT 
CAGCGCAGCT GCTCCCTGGA CCTAGGAGAC ACCGGAGGAT GCTACGGGTA TGCCAGGCGC 
CTGGGAGGAG CCTGGGCCCG GCGGAGCCAC TCTGTACATG GGGGGCTGCT GGGAGCTGGG 
TGTCGGGGGG TGGGGGGCAG TGCGGAGCGG CTGGAGGAGA GTGTGGTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_700437.2
CDS	716..2626
Translation	MAPPLLLLLLASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARSFGDLESLRSLHLDGNRLVELGSSSLRGPVNLQHLILSGNQLGRIAPGAFDDFLDSLEDLDVSYNNLRQVPWAGIGSMPALHTLNLDHNLIDALPPGVFAQLSQLSRLDLTSNRLATLAPDPLFSRGRDAEASPSPLVLSFSGNPLHCNCELLWLRRLARPDDLETCASPPTLAGRYFWAVPEGEFSCEPPLIARHTQRLWVLEGQRATLRCRALGDPVPTMHWVGPDDRLVGNSSRAWAFPNGTLEIGVTGAGDAGAYTCIATNPAGEATARVELRVLALPHGGNTSAEGGRPGPSDIAASARTAAEGEGTLESEPAVQVTEVTATSGLVSWGLGRPADPVWMFQIQYNSSEDETLIYRIVPASSHHFLLKHLVPGADYDLCLLALSPAAGPSDLTATRLLGCAHFSTLPATPLCHALQAHVLGGTLTVAVGGVLVAALLVFTVALLVRGRGAGNGRLPLKLSHVQSQTNGGTSPMPKSHPPRSPPPRPQRSCSLDLGDTGGCYGYARRLGGAWARRSHSVHGGLLGAGCRGVGGSAERLEESVV

Target ORF information:

RefSeq Version	NM_153388.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus leucine rich repeat and fibronectin type III domain containing 4 (Lrfn4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153388.4

ORF Insert Sequence:

ATGGCCCCGC CGCTCCTATT GCTGCTGCTG GCCAGTGGAG CCGCTGCTTG CCCGCTACCC 
TGTGTGTGCC AGAACCTGTC GGAGTCACTC AGCACCCTTT GTGCCCACCG AGGCCTGCTG 
TTTGTGCCAC CCAACGTGGA CAGGCGCACA GTTGAACTGC GCCTGGCCGA CAACTTCATC 
CAGGCCCTGG GACCACCTGA CTTCCGCAAC ATGACAGGGC TGGTGGACCT AACATTGTCT 
CGAAATGCCA TCACCCGCAT TGGGGCTCGC TCCTTTGGGG ACCTGGAGAG CCTGCGCTCC 
TTGCACCTGG ATGGCAACAG GCTGGTGGAG CTGGGCAGCA GCAGCCTACG GGGGCCTGTC 
AACCTCCAGC ATCTCATTCT CAGTGGCAAT CAACTGGGCC GCATCGCCCC CGGGGCCTTC 
GACGACTTCC TTGACAGTCT CGAGGACCTG GATGTGTCCT ATAACAACCT CCGGCAGGTT 
CCCTGGGCTG GCATAGGCTC CATGCCTGCC CTGCATACCC TGAACCTGGA CCATAACCTC 
ATCGATGCAC TACCCCCAGG TGTCTTTGCT CAGCTCAGCC AGCTCTCCCG CCTTGACCTC 
ACCTCCAACC GCCTGGCCAC CCTGGCACCT GATCCACTCT TCTCCCGAGG CCGGGATGCT 
GAGGCCTCAC CTTCTCCCCT GGTGCTGAGT TTCAGCGGGA ACCCACTGCA CTGCAACTGT 
GAGCTGCTGT GGCTGCGGCG GCTGGCCCGG CCCGATGACC TGGAAACCTG CGCTTCTCCA 
CCAACCCTGG CAGGCCGCTA CTTCTGGGCA GTGCCTGAGG GAGAGTTCTC CTGTGAGCCT 
CCGCTGATTG CCCGGCACAC ACAGCGCCTG TGGGTGCTAG AGGGCCAGCG GGCCACCCTA 
CGGTGCAGGG CCCTTGGTGA CCCTGTACCT ACCATGCACT GGGTTGGCCC TGATGACAGG 
CTGGTTGGCA ACTCTTCTCG AGCCTGGGCT TTCCCCAATG GGACCCTAGA GATTGGGGTG 
ACGGGCGCTG GAGATGCAGG AGCCTATACC TGCATTGCCA CCAACCCTGC TGGTGAGGCC 
ACAGCCCGAG TGGAGCTCCG GGTACTGGCC TTGCCCCATG GTGGGAACAC CAGTGCTGAG 
GGGGGCCGTC CTGGGCCTTC GGACATTGCT GCTTCTGCTA GAACTGCTGC CGAAGGCGAG 
GGAACTTTAG AATCTGAACC AGCAGTGCAA GTGACGGAGG TGACTGCCAC CTCTGGCCTG 
GTGAGCTGGG GCCTGGGGCG GCCAGCTGAC CCAGTGTGGA TGTTCCAAAT CCAGTACAAC 
AGCAGCGAGG ATGAGACCCT CATCTACCGG ATTGTACCAG CCTCCAGCCA CCACTTCCTG 
CTGAAGCACC TGGTTCCCGG TGCTGACTAC GACCTCTGCC TGCTGGCCCT GTCACCTGCT 
GCTGGGCCCT CCGACCTCAC GGCCACTAGA CTGCTGGGCT GTGCCCACTT CTCTACGCTA 
CCAGCCACCC CCCTGTGCCA TGCCCTACAG GCCCATGTGC TGGGCGGGAC CCTGACTGTG 
GCAGTGGGGG GCGTCCTAGT GGCTGCCTTA CTGGTCTTCA CTGTGGCCTT GCTGGTTCGG 
GGCCGGGGAG CTGGGAATGG CCGCCTCCCA CTCAAACTCA GCCATGTCCA ATCCCAGACC 
AATGGTGGCA CCAGCCCCAT GCCCAAGAGC CACCCACCAC GGAGCCCTCC ACCCCGTCCT 
CAGCGCAGCT GCTCCCTGGA CCTAGGAGAC ACCGGAGGAT GCTACGGGTA TGCCAGGCGC 
CTGGGAGGAG CCTGGGCCCG GCGGAGCCAC TCTGTACATG GGGGGCTGCT GGGAGCTGGG 
TGTCGGGGGG TGGGGGGCAG TGCGGAGCGG CTGGAGGAGA GTGTGGTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lrfn4 ( XM_017318142.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017173631.1 Mus musculus leucine rich repeat and fibronectin type III domain containing 4 (Lrfn4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu02376
Clone ID Related Accession (Same CDS sequence)	NM_153388.4 , XM_017318142.2 , XM_017318142.1
Accession Version	XM_017318142.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1911bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	leucine-rich repeat and fibronectin type-III domain-containing protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000085.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_017318142.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCCCGC CGCTCCTATT GCTGCTGCTG GCCAGTGGAG CCGCTGCTTG CCCGCTACCC 
TGTGTGTGCC AGAACCTGTC GGAGTCACTC AGCACCCTTT GTGCCCACCG AGGCCTGCTG 
TTTGTGCCAC CCAACGTGGA CAGGCGCACA GTTGAACTGC GCCTGGCCGA CAACTTCATC 
CAGGCCCTGG GACCACCTGA CTTCCGCAAC ATGACAGGGC TGGTGGACCT AACATTGTCT 
CGAAATGCCA TCACCCGCAT TGGGGCTCGC TCCTTTGGGG ACCTGGAGAG CCTGCGCTCC 
TTGCACCTGG ATGGCAACAG GCTGGTGGAG CTGGGCAGCA GCAGCCTACG GGGGCCTGTC 
AACCTCCAGC ATCTCATTCT CAGTGGCAAT CAACTGGGCC GCATCGCCCC CGGGGCCTTC 
GACGACTTCC TTGACAGTCT CGAGGACCTG GATGTGTCCT ATAACAACCT CCGGCAGGTT 
CCCTGGGCTG GCATAGGCTC CATGCCTGCC CTGCATACCC TGAACCTGGA CCATAACCTC 
ATCGATGCAC TACCCCCAGG TGTCTTTGCT CAGCTCAGCC AGCTCTCCCG CCTTGACCTC 
ACCTCCAACC GCCTGGCCAC CCTGGCACCT GATCCACTCT TCTCCCGAGG CCGGGATGCT 
GAGGCCTCAC CTTCTCCCCT GGTGCTGAGT TTCAGCGGGA ACCCACTGCA CTGCAACTGT 
GAGCTGCTGT GGCTGCGGCG GCTGGCCCGG CCCGATGACC TGGAAACCTG CGCTTCTCCA 
CCAACCCTGG CAGGCCGCTA CTTCTGGGCA GTGCCTGAGG GAGAGTTCTC CTGTGAGCCT 
CCGCTGATTG CCCGGCACAC ACAGCGCCTG TGGGTGCTAG AGGGCCAGCG GGCCACCCTA 
CGGTGCAGGG CCCTTGGTGA CCCTGTACCT ACCATGCACT GGGTTGGCCC TGATGACAGG 
CTGGTTGGCA ACTCTTCTCG AGCCTGGGCT TTCCCCAATG GGACCCTAGA GATTGGGGTG 
ACGGGCGCTG GAGATGCAGG AGCCTATACC TGCATTGCCA CCAACCCTGC TGGTGAGGCC 
ACAGCCCGAG TGGAGCTCCG GGTACTGGCC TTGCCCCATG GTGGGAACAC CAGTGCTGAG 
GGGGGCCGTC CTGGGCCTTC GGACATTGCT GCTTCTGCTA GAACTGCTGC CGAAGGCGAG 
GGAACTTTAG AATCTGAACC AGCAGTGCAA GTGACGGAGG TGACTGCCAC CTCTGGCCTG 
GTGAGCTGGG GCCTGGGGCG GCCAGCTGAC CCAGTGTGGA TGTTCCAAAT CCAGTACAAC 
AGCAGCGAGG ATGAGACCCT CATCTACCGG ATTGTACCAG CCTCCAGCCA CCACTTCCTG 
CTGAAGCACC TGGTTCCCGG TGCTGACTAC GACCTCTGCC TGCTGGCCCT GTCACCTGCT 
GCTGGGCCCT CCGACCTCAC GGCCACTAGA CTGCTGGGCT GTGCCCACTT CTCTACGCTA 
CCAGCCACCC CCCTGTGCCA TGCCCTACAG GCCCATGTGC TGGGCGGGAC CCTGACTGTG 
GCAGTGGGGG GCGTCCTAGT GGCTGCCTTA CTGGTCTTCA CTGTGGCCTT GCTGGTTCGG 
GGCCGGGGAG CTGGGAATGG CCGCCTCCCA CTCAAACTCA GCCATGTCCA ATCCCAGACC 
AATGGTGGCA CCAGCCCCAT GCCCAAGAGC CACCCACCAC GGAGCCCTCC ACCCCGTCCT 
CAGCGCAGCT GCTCCCTGGA CCTAGGAGAC ACCGGAGGAT GCTACGGGTA TGCCAGGCGC 
CTGGGAGGAG CCTGGGCCCG GCGGAGCCAC TCTGTACATG GGGGGCTGCT GGGAGCTGGG 
TGTCGGGGGG TGGGGGGCAG TGCGGAGCGG CTGGAGGAGA GTGTGGTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017173631.1
CDS	1150..3060
Translation	MAPPLLLLLLASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARSFGDLESLRSLHLDGNRLVELGSSSLRGPVNLQHLILSGNQLGRIAPGAFDDFLDSLEDLDVSYNNLRQVPWAGIGSMPALHTLNLDHNLIDALPPGVFAQLSQLSRLDLTSNRLATLAPDPLFSRGRDAEASPSPLVLSFSGNPLHCNCELLWLRRLARPDDLETCASPPTLAGRYFWAVPEGEFSCEPPLIARHTQRLWVLEGQRATLRCRALGDPVPTMHWVGPDDRLVGNSSRAWAFPNGTLEIGVTGAGDAGAYTCIATNPAGEATARVELRVLALPHGGNTSAEGGRPGPSDIAASARTAAEGEGTLESEPAVQVTEVTATSGLVSWGLGRPADPVWMFQIQYNSSEDETLIYRIVPASSHHFLLKHLVPGADYDLCLLALSPAAGPSDLTATRLLGCAHFSTLPATPLCHALQAHVLGGTLTVAVGGVLVAALLVFTVALLVRGRGAGNGRLPLKLSHVQSQTNGGTSPMPKSHPPRSPPPRPQRSCSLDLGDTGGCYGYARRLGGAWARRSHSVHGGLLGAGCRGVGGSAERLEESVV

Target ORF information:

RefSeq Version	XM_017318142.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus leucine rich repeat and fibronectin type III domain containing 4 (Lrfn4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017318142.2

ORF Insert Sequence:

ATGGCCCCGC CGCTCCTATT GCTGCTGCTG GCCAGTGGAG CCGCTGCTTG CCCGCTACCC 
TGTGTGTGCC AGAACCTGTC GGAGTCACTC AGCACCCTTT GTGCCCACCG AGGCCTGCTG 
TTTGTGCCAC CCAACGTGGA CAGGCGCACA GTTGAACTGC GCCTGGCCGA CAACTTCATC 
CAGGCCCTGG GACCACCTGA CTTCCGCAAC ATGACAGGGC TGGTGGACCT AACATTGTCT 
CGAAATGCCA TCACCCGCAT TGGGGCTCGC TCCTTTGGGG ACCTGGAGAG CCTGCGCTCC 
TTGCACCTGG ATGGCAACAG GCTGGTGGAG CTGGGCAGCA GCAGCCTACG GGGGCCTGTC 
AACCTCCAGC ATCTCATTCT CAGTGGCAAT CAACTGGGCC GCATCGCCCC CGGGGCCTTC 
GACGACTTCC TTGACAGTCT CGAGGACCTG GATGTGTCCT ATAACAACCT CCGGCAGGTT 
CCCTGGGCTG GCATAGGCTC CATGCCTGCC CTGCATACCC TGAACCTGGA CCATAACCTC 
ATCGATGCAC TACCCCCAGG TGTCTTTGCT CAGCTCAGCC AGCTCTCCCG CCTTGACCTC 
ACCTCCAACC GCCTGGCCAC CCTGGCACCT GATCCACTCT TCTCCCGAGG CCGGGATGCT 
GAGGCCTCAC CTTCTCCCCT GGTGCTGAGT TTCAGCGGGA ACCCACTGCA CTGCAACTGT 
GAGCTGCTGT GGCTGCGGCG GCTGGCCCGG CCCGATGACC TGGAAACCTG CGCTTCTCCA 
CCAACCCTGG CAGGCCGCTA CTTCTGGGCA GTGCCTGAGG GAGAGTTCTC CTGTGAGCCT 
CCGCTGATTG CCCGGCACAC ACAGCGCCTG TGGGTGCTAG AGGGCCAGCG GGCCACCCTA 
CGGTGCAGGG CCCTTGGTGA CCCTGTACCT ACCATGCACT GGGTTGGCCC TGATGACAGG 
CTGGTTGGCA ACTCTTCTCG AGCCTGGGCT TTCCCCAATG GGACCCTAGA GATTGGGGTG 
ACGGGCGCTG GAGATGCAGG AGCCTATACC TGCATTGCCA CCAACCCTGC TGGTGAGGCC 
ACAGCCCGAG TGGAGCTCCG GGTACTGGCC TTGCCCCATG GTGGGAACAC CAGTGCTGAG 
GGGGGCCGTC CTGGGCCTTC GGACATTGCT GCTTCTGCTA GAACTGCTGC CGAAGGCGAG 
GGAACTTTAG AATCTGAACC AGCAGTGCAA GTGACGGAGG TGACTGCCAC CTCTGGCCTG 
GTGAGCTGGG GCCTGGGGCG GCCAGCTGAC CCAGTGTGGA TGTTCCAAAT CCAGTACAAC 
AGCAGCGAGG ATGAGACCCT CATCTACCGG ATTGTACCAG CCTCCAGCCA CCACTTCCTG 
CTGAAGCACC TGGTTCCCGG TGCTGACTAC GACCTCTGCC TGCTGGCCCT GTCACCTGCT 
GCTGGGCCCT CCGACCTCAC GGCCACTAGA CTGCTGGGCT GTGCCCACTT CTCTACGCTA 
CCAGCCACCC CCCTGTGCCA TGCCCTACAG GCCCATGTGC TGGGCGGGAC CCTGACTGTG 
GCAGTGGGGG GCGTCCTAGT GGCTGCCTTA CTGGTCTTCA CTGTGGCCTT GCTGGTTCGG 
GGCCGGGGAG CTGGGAATGG CCGCCTCCCA CTCAAACTCA GCCATGTCCA ATCCCAGACC 
AATGGTGGCA CCAGCCCCAT GCCCAAGAGC CACCCACCAC GGAGCCCTCC ACCCCGTCCT 
CAGCGCAGCT GCTCCCTGGA CCTAGGAGAC ACCGGAGGAT GCTACGGGTA TGCCAGGCGC 
CTGGGAGGAG CCTGGGCCCG GCGGAGCCAC TCTGTACATG GGGGGCTGCT GGGAGCTGGG 
TGTCGGGGGG TGGGGGGCAG TGCGGAGCGG CTGGAGGAGA GTGTGGTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lrfn4 ( XM_017318142.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017173631.1 Mus musculus leucine rich repeat and fibronectin type III domain containing 4 (Lrfn4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu02376
Clone ID Related Accession (Same CDS sequence)	NM_153388.4 , XM_017318142.2 , XM_017318142.1
Accession Version	XM_017318142.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1911bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	leucine-rich repeat and fibronectin type-III domain-containing protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000085.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCCCGC CGCTCCTATT GCTGCTGCTG GCCAGTGGAG CCGCTGCTTG CCCGCTACCC 
TGTGTGTGCC AGAACCTGTC GGAGTCACTC AGCACCCTTT GTGCCCACCG AGGCCTGCTG 
TTTGTGCCAC CCAACGTGGA CAGGCGCACA GTTGAACTGC GCCTGGCCGA CAACTTCATC 
CAGGCCCTGG GACCACCTGA CTTCCGCAAC ATGACAGGGC TGGTGGACCT AACATTGTCT 
CGAAATGCCA TCACCCGCAT TGGGGCTCGC TCCTTTGGGG ACCTGGAGAG CCTGCGCTCC 
TTGCACCTGG ATGGCAACAG GCTGGTGGAG CTGGGCAGCA GCAGCCTACG GGGGCCTGTC 
AACCTCCAGC ATCTCATTCT CAGTGGCAAT CAACTGGGCC GCATCGCCCC CGGGGCCTTC 
GACGACTTCC TTGACAGTCT CGAGGACCTG GATGTGTCCT ATAACAACCT CCGGCAGGTT 
CCCTGGGCTG GCATAGGCTC CATGCCTGCC CTGCATACCC TGAACCTGGA CCATAACCTC 
ATCGATGCAC TACCCCCAGG TGTCTTTGCT CAGCTCAGCC AGCTCTCCCG CCTTGACCTC 
ACCTCCAACC GCCTGGCCAC CCTGGCACCT GATCCACTCT TCTCCCGAGG CCGGGATGCT 
GAGGCCTCAC CTTCTCCCCT GGTGCTGAGT TTCAGCGGGA ACCCACTGCA CTGCAACTGT 
GAGCTGCTGT GGCTGCGGCG GCTGGCCCGG CCCGATGACC TGGAAACCTG CGCTTCTCCA 
CCAACCCTGG CAGGCCGCTA CTTCTGGGCA GTGCCTGAGG GAGAGTTCTC CTGTGAGCCT 
CCGCTGATTG CCCGGCACAC ACAGCGCCTG TGGGTGCTAG AGGGCCAGCG GGCCACCCTA 
CGGTGCAGGG CCCTTGGTGA CCCTGTACCT ACCATGCACT GGGTTGGCCC TGATGACAGG 
CTGGTTGGCA ACTCTTCTCG AGCCTGGGCT TTCCCCAATG GGACCCTAGA GATTGGGGTG 
ACGGGCGCTG GAGATGCAGG AGCCTATACC TGCATTGCCA CCAACCCTGC TGGTGAGGCC 
ACAGCCCGAG TGGAGCTCCG GGTACTGGCC TTGCCCCATG GTGGGAACAC CAGTGCTGAG 
GGGGGCCGTC CTGGGCCTTC GGACATTGCT GCTTCTGCTA GAACTGCTGC CGAAGGCGAG 
GGAACTTTAG AATCTGAACC AGCAGTGCAA GTGACGGAGG TGACTGCCAC CTCTGGCCTG 
GTGAGCTGGG GCCTGGGGCG GCCAGCTGAC CCAGTGTGGA TGTTCCAAAT CCAGTACAAC 
AGCAGCGAGG ATGAGACCCT CATCTACCGG ATTGTACCAG CCTCCAGCCA CCACTTCCTG 
CTGAAGCACC TGGTTCCCGG TGCTGACTAC GACCTCTGCC TGCTGGCCCT GTCACCTGCT 
GCTGGGCCCT CCGACCTCAC GGCCACTAGA CTGCTGGGCT GTGCCCACTT CTCTACGCTA 
CCAGCCACCC CCCTGTGCCA TGCCCTACAG GCCCATGTGC TGGGCGGGAC CCTGACTGTG 
GCAGTGGGGG GCGTCCTAGT GGCTGCCTTA CTGGTCTTCA CTGTGGCCTT GCTGGTTCGG 
GGCCGGGGAG CTGGGAATGG CCGCCTCCCA CTCAAACTCA GCCATGTCCA ATCCCAGACC 
AATGGTGGCA CCAGCCCCAT GCCCAAGAGC CACCCACCAC GGAGCCCTCC ACCCCGTCCT 
CAGCGCAGCT GCTCCCTGGA CCTAGGAGAC ACCGGAGGAT GCTACGGGTA TGCCAGGCGC 
CTGGGAGGAG CCTGGGCCCG GCGGAGCCAC TCTGTACATG GGGGGCTGCT GGGAGCTGGG 
TGTCGGGGGG TGGGGGGCAG TGCGGAGCGG CTGGAGGAGA GTGTGGTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017173631.1
CDS	323..2233
Translation	MAPPLLLLLLASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARSFGDLESLRSLHLDGNRLVELGSSSLRGPVNLQHLILSGNQLGRIAPGAFDDFLDSLEDLDVSYNNLRQVPWAGIGSMPALHTLNLDHNLIDALPPGVFAQLSQLSRLDLTSNRLATLAPDPLFSRGRDAEASPSPLVLSFSGNPLHCNCELLWLRRLARPDDLETCASPPTLAGRYFWAVPEGEFSCEPPLIARHTQRLWVLEGQRATLRCRALGDPVPTMHWVGPDDRLVGNSSRAWAFPNGTLEIGVTGAGDAGAYTCIATNPAGEATARVELRVLALPHGGNTSAEGGRPGPSDIAASARTAAEGEGTLESEPAVQVTEVTATSGLVSWGLGRPADPVWMFQIQYNSSEDETLIYRIVPASSHHFLLKHLVPGADYDLCLLALSPAAGPSDLTATRLLGCAHFSTLPATPLCHALQAHVLGGTLTVAVGGVLVAALLVFTVALLVRGRGAGNGRLPLKLSHVQSQTNGGTSPMPKSHPPRSPPPRPQRSCSLDLGDTGGCYGYARRLGGAWARRSHSVHGGLLGAGCRGVGGSAERLEESVV

Target ORF information:

RefSeq Version	XM_017318142.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus leucine rich repeat and fibronectin type III domain containing 4 (Lrfn4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017318142.1

ORF Insert Sequence:

ATGGCCCCGC CGCTCCTATT GCTGCTGCTG GCCAGTGGAG CCGCTGCTTG CCCGCTACCC 
TGTGTGTGCC AGAACCTGTC GGAGTCACTC AGCACCCTTT GTGCCCACCG AGGCCTGCTG 
TTTGTGCCAC CCAACGTGGA CAGGCGCACA GTTGAACTGC GCCTGGCCGA CAACTTCATC 
CAGGCCCTGG GACCACCTGA CTTCCGCAAC ATGACAGGGC TGGTGGACCT AACATTGTCT 
CGAAATGCCA TCACCCGCAT TGGGGCTCGC TCCTTTGGGG ACCTGGAGAG CCTGCGCTCC 
TTGCACCTGG ATGGCAACAG GCTGGTGGAG CTGGGCAGCA GCAGCCTACG GGGGCCTGTC 
AACCTCCAGC ATCTCATTCT CAGTGGCAAT CAACTGGGCC GCATCGCCCC CGGGGCCTTC 
GACGACTTCC TTGACAGTCT CGAGGACCTG GATGTGTCCT ATAACAACCT CCGGCAGGTT 
CCCTGGGCTG GCATAGGCTC CATGCCTGCC CTGCATACCC TGAACCTGGA CCATAACCTC 
ATCGATGCAC TACCCCCAGG TGTCTTTGCT CAGCTCAGCC AGCTCTCCCG CCTTGACCTC 
ACCTCCAACC GCCTGGCCAC CCTGGCACCT GATCCACTCT TCTCCCGAGG CCGGGATGCT 
GAGGCCTCAC CTTCTCCCCT GGTGCTGAGT TTCAGCGGGA ACCCACTGCA CTGCAACTGT 
GAGCTGCTGT GGCTGCGGCG GCTGGCCCGG CCCGATGACC TGGAAACCTG CGCTTCTCCA 
CCAACCCTGG CAGGCCGCTA CTTCTGGGCA GTGCCTGAGG GAGAGTTCTC CTGTGAGCCT 
CCGCTGATTG CCCGGCACAC ACAGCGCCTG TGGGTGCTAG AGGGCCAGCG GGCCACCCTA 
CGGTGCAGGG CCCTTGGTGA CCCTGTACCT ACCATGCACT GGGTTGGCCC TGATGACAGG 
CTGGTTGGCA ACTCTTCTCG AGCCTGGGCT TTCCCCAATG GGACCCTAGA GATTGGGGTG 
ACGGGCGCTG GAGATGCAGG AGCCTATACC TGCATTGCCA CCAACCCTGC TGGTGAGGCC 
ACAGCCCGAG TGGAGCTCCG GGTACTGGCC TTGCCCCATG GTGGGAACAC CAGTGCTGAG 
GGGGGCCGTC CTGGGCCTTC GGACATTGCT GCTTCTGCTA GAACTGCTGC CGAAGGCGAG 
GGAACTTTAG AATCTGAACC AGCAGTGCAA GTGACGGAGG TGACTGCCAC CTCTGGCCTG 
GTGAGCTGGG GCCTGGGGCG GCCAGCTGAC CCAGTGTGGA TGTTCCAAAT CCAGTACAAC 
AGCAGCGAGG ATGAGACCCT CATCTACCGG ATTGTACCAG CCTCCAGCCA CCACTTCCTG 
CTGAAGCACC TGGTTCCCGG TGCTGACTAC GACCTCTGCC TGCTGGCCCT GTCACCTGCT 
GCTGGGCCCT CCGACCTCAC GGCCACTAGA CTGCTGGGCT GTGCCCACTT CTCTACGCTA 
CCAGCCACCC CCCTGTGCCA TGCCCTACAG GCCCATGTGC TGGGCGGGAC CCTGACTGTG 
GCAGTGGGGG GCGTCCTAGT GGCTGCCTTA CTGGTCTTCA CTGTGGCCTT GCTGGTTCGG 
GGCCGGGGAG CTGGGAATGG CCGCCTCCCA CTCAAACTCA GCCATGTCCA ATCCCAGACC 
AATGGTGGCA CCAGCCCCAT GCCCAAGAGC CACCCACCAC GGAGCCCTCC ACCCCGTCCT 
CAGCGCAGCT GCTCCCTGGA CCTAGGAGAC ACCGGAGGAT GCTACGGGTA TGCCAGGCGC 
CTGGGAGGAG CCTGGGCCCG GCGGAGCCAC TCTGTACATG GGGGGCTGCT GGGAGCTGGG 
TGTCGGGGGG TGGGGGGCAG TGCGGAGCGG CTGGAGGAGA GTGTGGTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3-LAR adhesion.
Nature communications712328(2016 Aug)
Lie E,Ko JS,Choi SY,Roh JD,Cho YS,Noh R,Kim D,Li Y,Kang H,Choi TY,Nam J,Mah W,Lee D,Lee SG,Kim HM,Kim H,Choi SY,Um JW,Kang MG,Bae YC,Ko J,Kim E

Splicing-Dependent Trans-synaptic SALM3-LAR-RPTP Interactions Regulate Excitatory Synapse Development and Locomotion.
Cell reports12(10)1618-30(2015 Sep)
Li Y,Zhang P,Choi TY,Park SK,Park H,Lee EJ,Lee D,Roh JD,Mah W,Kim R,Kim Y,Kwon H,Bae YC,Choi SY,Craig AM,Kim E

miR-15b/16-2 deletion promotes B-cell malignancies.
Proceedings of the National Academy of Sciences of the United States of America112(37)11636-41(2015 Sep)
Lovat F,Fassan M,Gasparini P,Rizzotto L,Cascione L,Pizzi M,Vicentini C,Balatti V,Palmieri D,Costinean S,Croce CM

The SALM/Lrfn family of leucine-rich repeat-containing cell adhesion molecules.
Seminars in cell & developmental biology22(5)492-8(2011 Jul)
Nam J,Mah W,Kim E

Selected SALM (synaptic adhesion-like molecule) family proteins regulate synapse formation.
The Journal of neuroscience : the official journal of the Society for Neuroscience30(16)5559-68(2010 Apr)
Mah W,Ko J,Nam J,Han K,Chung WS,Kim E

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Lrfn4 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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