Ofcc1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ofcc1
Entrez Gene ID	218165
Full Name	orofacial cleft 1 candidate 1
Synonyms	opo
General protein information	Preferred Names orofacial cleft 1 candidate 1 Names orofacial cleft 1 candidate gene 1 protein homolog ojoplano orofacial clefting chromosomal breakpoint region candidate 1 protein homolog
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13\|13 A3.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_172143.2	NP_742155.2	orofacial cleft 1 candidate gene 1 protein homolog

Pathways from BioSystems

Homologies

Bos taurus (cattle)	OFCC1	XP_002697640.3
Homo sapiens (human)	OFCC1	XP_003118606.3
Pan troglodytes (chimpanzee)	OFCC1	XP_001175036.3
Danio rerio (zebrafish)	LOC101883978	XP_005174689.1
Canis lupus familiaris (dog)	LOC609660	XP_005640216.1
Gallus gallus (chicken)	LOC100859006	XP_004939758.1
Xenopus tropicalis (tropical clawed frog)	LOC101732008	XP_004915724.1
Mus musculus (house mouse)	Ofcc1	NP_742155.2

Gene Ontology
Bibliography

Related articles in PubMed

Ablation of Mrds1/Ofcc1 induces hyper-?-glutamyl transpeptidasemia without abnormal head development and schizophrenia-relevant behaviors in mice.
Ohnishi T, Yamada K, Watanabe A, Ohba H, Sakaguchi T, Honma Y, Iwayama Y, Toyota T, Maekawa M, Watanabe K, Detera-Wadleigh SD, Wakana S, Yoshikawa T
PloS one6(12)e29499(2011)

Cloning of mouse ojoplano, a reticular cytoplasmic protein expressed during embryonic development.
Mertes F, Martinez-Morales JR, Nolden T, Sp?rle R, Wittbrodt J, Lehrach H, Himmelbauer H
Gene expression patterns : GEP9(8)562-7(2009 Dec)

Fabp7 maps to a quantitative trait locus for a schizophrenia endophenotype.
Watanabe A, Toyota T, Owada Y, Hayashi T, Iwayama Y, Matsumata M, Ishitsuka Y, Nakaya A, Maekawa M, Ohnishi T, Arai R, Sakurai K, Yamada K, Kondo H, Hashimoto K, Osumi N, Yoshikawa T
PLoS biology5(11)e297(2007 Nov)

Mapping of three translocation breakpoints associated with orofacial clefting within 6p24 and identification of new transcripts within the region.
Davies SJ, Wise C, Venkatesh B, Mirza G, Jefferson A, Volpi EV, Ragoussis J
Cytogenetic and genome research105(1)47-53(2004)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Disruption of the Mrds1/Ofcc1 gene elicits asymptomatic hyper-gamma-glutamyl-transpeptidasemia in mice.
Title: Ablation of Mrds1/Ofcc1 induces hyper-?-glutamyl transpeptidasemia without abnormal head development and schizophrenia-relevant behaviors in mice.

Opo shows homology to human transcripts linked to a hereditary craniofacial malformation, orofacial cleft 1 (OFC1). The expression of mouse Opo in neural crest derivatives and skull elements further supports this link.
Title: Cloning of mouse ojoplano, a reticular cytoplasmic protein expressed during embryonic development.

The following Ofcc1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ofcc1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu03104	NM_172143.2 Latest version!	Mus musculus orofacial cleft 1 candidate 1 (Ofcc1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ofcc1 ( NM_172143.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_742155.2 Mus musculus orofacial cleft 1 candidate 1 (Ofcc1), mRNA.

Price & Availability↑

CloneID	OMu03104
Clone ID Related Accession (Same CDS sequence)	NM_172143.2
Accession Version	NM_172143.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2781bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	orofacial cleft 1 candidate gene 1 protein homolog
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EU683438.1. On or before Aug 30, 2009 this sequence version replaced XM_001473617.1, XM_001471988.1, NM_172143.1. ##Evidence-Data-START## Transcript exon combination :: EU683438.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGATAAAG AGAAGTTTCA GCAGAAGGCT GTGAAGCAAA CTAAGCAGAA GAAATCCACG 
TCGGCTGAAT TTCTGATGGT TAAAGAATAC ACGGACGCTA CCGAAGGTGC CGGGAATCCA 
GGTTTTAACA TGAGCAGCCC AGAACTCCCA GCACATCAGA CTCCACAAGA GAAAGTTGTG 
AGACATGACA TGCTGGATCA CACCCTTGCA ACTCATCAAC AAAAATCCAG GCTGCCAGCT 
TCAGCGGGAC CCAAAGGAAA TGAATACAGC AGAAATTACT TTGACCCACT GACGGAGGAG 
GAAATAAACT CAAGGCAGTG CCGGATGGAG GTCAGCAGAC AGGATGGAAG GTCAAAGGTG 
GAGACACTGG ATCAGGAATC ACCCAGACGT TCCACTGAGA GCCTGGATAC CTGCAAAGAG 
GATGAGGAAG ATGCTCCTGG GTACACTGAG GACTCTGAGA GGCAAGCTCA GAGAGGCGCT 
GTTCTGCTTG CAGGTTCTTC ATCAGGACAG GATTTGGAAT TTGAAAGAAA AGGACTCAGC 
CAGAACATTC CCATGTCATG TTTAAAGAAA GAAAAAGCAT TCAAGAAAGC TCCGAGTCAG 
CTGTGCACTG CAGACGGGAA TCCTTACACA AAGGCTAGTG ACAAGGGGCA ACGCTCATTT 
CCAGAAGTGA CTAAAGAATC TGGAAGGACA GAAGGAACTT GCTGGAAGGG TGAGCAGCCT 
CAGTTGCCTA GTCTACAAAT ACAGATCAGA TGTATTAGGG GCCTCAAGGA CAAGGCTCCC 
CAAGGCTCCT ACCTCCTCCG AGTGTCTCTG CTCAGTCAGC TGGGGAGCTG TGCCTCACAG 
GAGTGTCAAG CTGAGCAGCT GAAGACAAGG ACGTGCCCAG TTCTTCATGG TGGCAACTTT 
TATGATGTGG GGCTCTATTT CCATGAAAGC GTTTCTGTGG TACTTCCTCA AAGGAAAGCC 
GTGAAGCCTG GCTTGTCTTT CTTGTTTGAA CTCTTCCTTC TCCATGGAAC ATATGCTTAC 
AATGACCTGA TTATGGGCTG GGCAGTCTTT CCTGTATGTG ACAACAACTT CCATATAGTA 
GAGGGAAAAT TCAAGTGTCC CCTTCTCCGA GGACCTTATG ACCAAAAACT GGACAGCTTC 
AGAAAAATAG AAAATTTGAT TTGCCAAGAC TTGGACCAGT GGCTGTGCAA TCTATATTTT 
AAGGTAATTA AAACTCCTTT GCATTTGGAT GATCAAAAAA GCCCTGAGAG CCGCAGGCAG 
CTTTCTCCAG AACGTCCAGT GTGCTTAATG GTGGAAGCAG AGAACACGGA ATTCGATTTG 
GATAATACAG CCGGTCCTTC AAAGAAAGAA CCGCCAGGAA ATGTTCATGC TGTAATGGGC 
GGTGCGATCC ACTCTTCTCA AGGGAATATT TCTAATAAAA CTGACTCCTG CCCTAGGGGT 
TGTGATCTGT GCCTCTTCAA AGAAGCCCGT GACTTGCAAG CTATGGGGAA TAGTTTGGCT 
GCTCAATCTG TGAAGGAAAG ATCTACTGTG TGGAGACCTG AAGATCCTGA AGACTATCCG 
GGGGATGTGT CTTACCTAGA GGAACTGGAG AAATATCAGT TTTCCGTTTG CTGCCCTTCA 
GGTGTAGATG GCTGTGGATC TGGAAGGTTG TCCAAGCACC TCCACTTCAC ATTGATGGCC 
TTATTTTCAG AACTTGAATT AGCTCAATGG CAAAGTCAGA GCTTCTGGTA CATCCTTCTG 
ATGATGGCAT CTCTCTGGTT CGTGAGGCTC TACCTGCATT ACCTGGGCCA GTGGCTTTTC 
CTCTGGGTCC TCTCCACTCC AGTTACAAAA TTCCAGTTTC ACTCCTACAC TGTTGAGCTC 
TGCTACCTGA CTTCTTCACT TCATGTCGGA GAAGAGCTGG CTGTGATTGT ATTGGGGCCC 
TTAGCTCTAA ACACAATCAC GTTCCCCTTG CTTCTGATCA GATGGGGCTG TCAGCTACTG 
TTTTCCTCCT GCCCAGATGC CTTGTCAAAG CTAATCATCA CGATGGGACT ATGGACAGTT 
CTAGACCCAT TGGCGGTGTT TCTAGTGGAT GCTTTCCTGG GGCGACTTGC ACATAATGGG 
GAGACACCTA TTGCAGATGC AGCTAAACTC TACTGGATGT TCCTGAGAAC CAAGCAACCA 
GCCATCCTCG GTGCTCTGAT CACAGTGGTA GTTTACACTC TGCTGTTTGT CATCTCCTCC 
TTGATTTTGT ACTTGTATTG CCTCAGGTTG TACAATGACT CTTGGGTATT AGATGCATTT 
CAGAGAATCC ACAGTGAAGA AGGCAAGTTC TTCATACCAC ATGATTTGGA AATTTCCAAT 
CAGGAGCTGA GTCACATCGT GAAAAGATCT GAGCAGTGGA GAGGGATCCA TGGTGAGAGA 
AGGAAGGTGG CAGTGCACGA TTACATCTGC AAAAGCCATG ACACCGAGTC CAAGGTCTCC 
AGCTGTGACC CCCACCATCA GGATGAAAGT TTTGAGTCTG CAGTTGGTCC AAGAAGGGTT 
ACTTCCCACA TATCAGTACA TACTGTTTAT CCCAATGGGT TTCAAGAGTT GTATCGCCAT 
TTTCTCAGGC TCCCGGATGG CGCCATCATT GAGGTGTTTG GTGACATCAG TGCCTTGAGA 
TTTGTCCCCA GTGAAGTGAT CACCGCTATT GAGGAACACA TAAGAGAAAT GGACACTGTG 
CAGAGAGAAA TCTTTGCTTC TTACCAAGAG AAAGAAGTCT CTGAGCATAA AAGGAGATCA 
TTAACCCGAG TGGAAAAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_742155.2
CDS	29..2809
Translation	MDKEKFQQKAVKQTKQKKSTSAEFLMVKEYTDATEGAGNPGFNMSSPELPAHQTPQEKVVRHDMLDHTLATHQQKSRLPASAGPKGNEYSRNYFDPLTEEEINSRQCRMEVSRQDGRSKVETLDQESPRRSTESLDTCKEDEEDAPGYTEDSERQAQRGAVLLAGSSSGQDLEFERKGLSQNIPMSCLKKEKAFKKAPSQLCTADGNPYTKASDKGQRSFPEVTKESGRTEGTCWKGEQPQLPSLQIQIRCIRGLKDKAPQGSYLLRVSLLSQLGSCASQECQAEQLKTRTCPVLHGGNFYDVGLYFHESVSVVLPQRKAVKPGLSFLFELFLLHGTYAYNDLIMGWAVFPVCDNNFHIVEGKFKCPLLRGPYDQKLDSFRKIENLICQDLDQWLCNLYFKVIKTPLHLDDQKSPESRRQLSPERPVCLMVEAENTEFDLDNTAGPSKKEPPGNVHAVMGGAIHSSQGNISNKTDSCPRGCDLCLFKEARDLQAMGNSLAAQSVKERSTVWRPEDPEDYPGDVSYLEELEKYQFSVCCPSGVDGCGSGRLSKHLHFTLMALFSELELAQWQSQSFWYILLMMASLWFVRLYLHYLGQWLFLWVLSTPVTKFQFHSYTVELCYLTSSLHVGEELAVIVLGPLALNTITFPLLLIRWGCQLLFSSCPDALSKLIITMGLWTVLDPLAVFLVDAFLGRLAHNGETPIADAAKLYWMFLRTKQPAILGALITVVVYTLLFVISSLILYLYCLRLYNDSWVLDAFQRIHSEEGKFFIPHDLEISNQELSHIVKRSEQWRGIHGERRKVAVHDYICKSHDTESKVSSCDPHHQDESFESAVGPRRVTSHISVHTVYPNGFQELYRHFLRLPDGAIIEVFGDISALRFVPSEVITAIEEHIREMDTVQREIFASYQEKEVSEHKRRSLTRVEK

Target ORF information:

RefSeq Version	NM_172143.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus orofacial cleft 1 candidate 1 (Ofcc1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172143.2

ORF Insert Sequence:

ATGGATAAAG AGAAGTTTCA GCAGAAGGCT GTGAAGCAAA CTAAGCAGAA GAAATCCACG 
TCGGCTGAAT TTCTGATGGT TAAAGAATAC ACGGACGCTA CCGAAGGTGC CGGGAATCCA 
GGTTTTAACA TGAGCAGCCC AGAACTCCCA GCACATCAGA CTCCACAAGA GAAAGTTGTG 
AGACATGACA TGCTGGATCA CACCCTTGCA ACTCATCAAC AAAAATCCAG GCTGCCAGCT 
TCAGCGGGAC CCAAAGGAAA TGAATACAGC AGAAATTACT TTGACCCACT GACGGAGGAG 
GAAATAAACT CAAGGCAGTG CCGGATGGAG GTCAGCAGAC AGGATGGAAG GTCAAAGGTG 
GAGACACTGG ATCAGGAATC ACCCAGACGT TCCACTGAGA GCCTGGATAC CTGCAAAGAG 
GATGAGGAAG ATGCTCCTGG GTACACTGAG GACTCTGAGA GGCAAGCTCA GAGAGGCGCT 
GTTCTGCTTG CAGGTTCTTC ATCAGGACAG GATTTGGAAT TTGAAAGAAA AGGACTCAGC 
CAGAACATTC CCATGTCATG TTTAAAGAAA GAAAAAGCAT TCAAGAAAGC TCCGAGTCAG 
CTGTGCACTG CAGACGGGAA TCCTTACACA AAGGCTAGTG ACAAGGGGCA ACGCTCATTT 
CCAGAAGTGA CTAAAGAATC TGGAAGGACA GAAGGAACTT GCTGGAAGGG TGAGCAGCCT 
CAGTTGCCTA GTCTACAAAT ACAGATCAGA TGTATTAGGG GCCTCAAGGA CAAGGCTCCC 
CAAGGCTCCT ACCTCCTCCG AGTGTCTCTG CTCAGTCAGC TGGGGAGCTG TGCCTCACAG 
GAGTGTCAAG CTGAGCAGCT GAAGACAAGG ACGTGCCCAG TTCTTCATGG TGGCAACTTT 
TATGATGTGG GGCTCTATTT CCATGAAAGC GTTTCTGTGG TACTTCCTCA AAGGAAAGCC 
GTGAAGCCTG GCTTGTCTTT CTTGTTTGAA CTCTTCCTTC TCCATGGAAC ATATGCTTAC 
AATGACCTGA TTATGGGCTG GGCAGTCTTT CCTGTATGTG ACAACAACTT CCATATAGTA 
GAGGGAAAAT TCAAGTGTCC CCTTCTCCGA GGACCTTATG ACCAAAAACT GGACAGCTTC 
AGAAAAATAG AAAATTTGAT TTGCCAAGAC TTGGACCAGT GGCTGTGCAA TCTATATTTT 
AAGGTAATTA AAACTCCTTT GCATTTGGAT GATCAAAAAA GCCCTGAGAG CCGCAGGCAG 
CTTTCTCCAG AACGTCCAGT GTGCTTAATG GTGGAAGCAG AGAACACGGA ATTCGATTTG 
GATAATACAG CCGGTCCTTC AAAGAAAGAA CCGCCAGGAA ATGTTCATGC TGTAATGGGC 
GGTGCGATCC ACTCTTCTCA AGGGAATATT TCTAATAAAA CTGACTCCTG CCCTAGGGGT 
TGTGATCTGT GCCTCTTCAA AGAAGCCCGT GACTTGCAAG CTATGGGGAA TAGTTTGGCT 
GCTCAATCTG TGAAGGAAAG ATCTACTGTG TGGAGACCTG AAGATCCTGA AGACTATCCG 
GGGGATGTGT CTTACCTAGA GGAACTGGAG AAATATCAGT TTTCCGTTTG CTGCCCTTCA 
GGTGTAGATG GCTGTGGATC TGGAAGGTTG TCCAAGCACC TCCACTTCAC ATTGATGGCC 
TTATTTTCAG AACTTGAATT AGCTCAATGG CAAAGTCAGA GCTTCTGGTA CATCCTTCTG 
ATGATGGCAT CTCTCTGGTT CGTGAGGCTC TACCTGCATT ACCTGGGCCA GTGGCTTTTC 
CTCTGGGTCC TCTCCACTCC AGTTACAAAA TTCCAGTTTC ACTCCTACAC TGTTGAGCTC 
TGCTACCTGA CTTCTTCACT TCATGTCGGA GAAGAGCTGG CTGTGATTGT ATTGGGGCCC 
TTAGCTCTAA ACACAATCAC GTTCCCCTTG CTTCTGATCA GATGGGGCTG TCAGCTACTG 
TTTTCCTCCT GCCCAGATGC CTTGTCAAAG CTAATCATCA CGATGGGACT ATGGACAGTT 
CTAGACCCAT TGGCGGTGTT TCTAGTGGAT GCTTTCCTGG GGCGACTTGC ACATAATGGG 
GAGACACCTA TTGCAGATGC AGCTAAACTC TACTGGATGT TCCTGAGAAC CAAGCAACCA 
GCCATCCTCG GTGCTCTGAT CACAGTGGTA GTTTACACTC TGCTGTTTGT CATCTCCTCC 
TTGATTTTGT ACTTGTATTG CCTCAGGTTG TACAATGACT CTTGGGTATT AGATGCATTT 
CAGAGAATCC ACAGTGAAGA AGGCAAGTTC TTCATACCAC ATGATTTGGA AATTTCCAAT 
CAGGAGCTGA GTCACATCGT GAAAAGATCT GAGCAGTGGA GAGGGATCCA TGGTGAGAGA 
AGGAAGGTGG CAGTGCACGA TTACATCTGC AAAAGCCATG ACACCGAGTC CAAGGTCTCC 
AGCTGTGACC CCCACCATCA GGATGAAAGT TTTGAGTCTG CAGTTGGTCC AAGAAGGGTT 
ACTTCCCACA TATCAGTACA TACTGTTTAT CCCAATGGGT TTCAAGAGTT GTATCGCCAT 
TTTCTCAGGC TCCCGGATGG CGCCATCATT GAGGTGTTTG GTGACATCAG TGCCTTGAGA 
TTTGTCCCCA GTGAAGTGAT CACCGCTATT GAGGAACACA TAAGAGAAAT GGACACTGTG 
CAGAGAGAAA TCTTTGCTTC TTACCAAGAG AAAGAAGTCT CTGAGCATAA AAGGAGATCA 
TTAACCCGAG TGGAAAAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Ablation of Mrds1/Ofcc1 induces hyper-?-glutamyl transpeptidasemia without abnormal head development and schizophrenia-relevant behaviors in mice.
PloS one6(12)e29499(2011)
Ohnishi T,Yamada K,Watanabe A,Ohba H,Sakaguchi T,Honma Y,Iwayama Y,Toyota T,Maekawa M,Watanabe K,Detera-Wadleigh SD,Wakana S,Yoshikawa T

Cloning of mouse ojoplano, a reticular cytoplasmic protein expressed during embryonic development.
Gene expression patterns : GEP9(8)562-7(2009 Dec)
Mertes F,Martinez-Morales JR,Nolden T,Sp?rle R,Wittbrodt J,Lehrach H,Himmelbauer H

Fabp7 maps to a quantitative trait locus for a schizophrenia endophenotype.
PLoS biology5(11)e297(2007 Nov)
Watanabe A,Toyota T,Owada Y,Hayashi T,Iwayama Y,Matsumata M,Ishitsuka Y,Nakaya A,Maekawa M,Ohnishi T,Arai R,Sakurai K,Yamada K,Kondo H,Hashimoto K,Osumi N,Yoshikawa T

Mapping of three translocation breakpoints associated with orofacial clefting within 6p24 and identification of new transcripts within the region.
Cytogenetic and genome research105(1)47-53(2004)
Davies SJ,Wise C,Venkatesh B,Mirza G,Jefferson A,Volpi EV,Ragoussis J

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Ofcc1 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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