Ahsa1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ahsa1
Entrez Gene ID	217737
Full Name	AHA1, activator of heat shock protein ATPase 1
Synonyms	BC023857,p38
General protein information	Preferred Names AHA1, activator of heat shock protein ATPase 1 Names activator of 90 kDa heat shock protein ATPase homolog 1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 AHA1, activator of heat shock protein ATPase homolog 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 12 Map Location: 12\|12 D2

mRNA and Protein(s)

mRNA	Protein	Name
NM_146036.1	NP_666148.1	activator of 90 kDa heat shock protein ATPase homolog 1
XM_006515729.2	XP_006515792.1	activator of 90 kDa heat shock protein ATPase homolog 1 isoform X1
XM_006515729.1	XP_006515792.1	activator of 90 kDa heat shock protein ATPase homolog 1 isoform X1
NM_146036.2	NP_666148.1	activator of 90 kDa heat shock protein ATPase homolog 1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	AHSA1	NP_001029838.1
Mus musculus (house mouse)	Ahsa1	NP_666148.1
Danio rerio (zebrafish)	ahsa1l	NP_997767.1
Oryza sativa (rice)	Os08g0464000	NP_001061992.1
Homo sapiens (human)	AHSA1	NP_036243.1
Pan troglodytes (chimpanzee)	AHSA1	XP_001165345.1
Gallus gallus (chicken)	AHSA1	XP_421292.1
Caenorhabditis elegans (roundworm)	CELE_C01G10.8	NP_506715.1
Schizosaccharomyces pombe (fission yeast)	SPBC1711.08	NP_595881.1
Neurospora crassa	NCU04087	XP_956083.1
Xenopus tropicalis (tropical clawed frog)	ahsa1	NP_001008135.2
Eremothecium gossypii	AGOS_AGL090W	NP_986576.1
Drosophila melanogaster (fruit fly)	CG1416	NP_610121.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010514	XP_314487.3
Saccharomyces cerevisiae (baker's yeast)	AHA1	NP_010500.3
Magnaporthe oryzae (rice blast fungus)	MGG_00814	XP_003718169.1
	AHSA1	XP_001103794.1
Canis lupus familiaris (dog)	AHSA1	XP_537523.2
Rattus norvegicus (Norway rat)	Ahsa1	NP_001108506.1
Kluyveromyces lactis	KLLA0A04147g	XP_451183.1
Arabidopsis thaliana (thale cress)	AT3G12050	NP_566410.1

Gene Ontology
Bibliography

Related articles in PubMed

Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients.
Woodford MR, Sager RA, Marris E, Dunn DM, Blanden AR, Murphy RL, Rensing N, Shapiro O, Panaretou B, Prodromou C, Loh SN, Gutmann DH, Bourboulia D, Bratslavsky G, Wong M, Mollapour M
The EMBO journal36(24)3650-3665(2017 12)

Modulation of the cochaperone AHA1 regulates heat-shock protein 90 and endothelial NO synthase activation by vascular endothelial growth factor.
Desjardins F, Delisle C, Gratton JP
Arteriosclerosis, thrombosis, and vascular biology32(10)2484-92(2012 Oct)

Dynamic tyrosine phosphorylation modulates cycling of the HSP90-P50(CDC37)-AHA1 chaperone machine.
Xu W, Mollapour M, Prodromou C, Wang S, Scroggins BT, Palchick Z, Beebe K, Siderius M, Lee MJ, Couvillon A, Trepel JB, Miyata Y, Matts R, Neckers L
Molecular cell47(3)434-43(2012 Aug)

An interaction network predicted from public data as a discovery tool: application to the Hsp90 molecular chaperone machine.
Echeverr?a PC, Bernthaler A, Dupuis P, Mayer B, Picard D
PloS one6(10)e26044(2011)

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic acids research31(1)278-81(2003 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Hsp90 phosphorylation on tyrosine313 promotes recruitment of AHA1, which stimulates Hsp90 ATPase activity, furthering the chaperoning process.
Title: Dynamic tyrosine phosphorylation modulates cycling of the HSP90-P50(CDC37)-AHA1 chaperone machine.

The following Ahsa1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ahsa1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu21652	NM_146036.2 Latest version!	Mus musculus AHA1, activator of heat shock protein ATPase 1 (Ahsa1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OMu47744	XM_006515729.2 Latest version!	Mus musculus AHA1, activator of heat shock protein ATPase 1 (Ahsa1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu47744	XM_006515729.1	Mus musculus AHA1, activator of heat shock protein ATPase 1 (Ahsa1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu21652	NM_146036.1	Mus musculus AHA1, activator of heat shock protein ATPase 1 (Ahsa1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ahsa1 ( XM_006515729.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006515792.1 Mus musculus AHA1, activator of heat shock protein ATPase 1 (Ahsa1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu47744
Clone ID Related Accession (Same CDS sequence)	XM_006515729.2 , XM_006515729.1
Accession Version	XM_006515729.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 612bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	activator of 90 kDa heat shock protein ATPase homolog 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGGAAG ACGGGGTGAA ACTTCTGAGA GAAGCAGTGG GAATTTACAT CAGCACCCTC 
AAGACAGAGT TTACTCAGGG CATGATCTTG CCCACAGTGA ATGGAGAGTC AGTAGATCCA 
GTGGGCCAGC CAGCACTAAA GACTGAGACT TGCAAGGCTA AGTCTGCTCC TTCAAAAAGC 
CAGGCCAAAC CTGTTGGTGT CAAAATCCCC ACTTGTAAGA TCACCCTTAA AGAAACCTTC 
CTGACCTCCC CAGAGGAGCT CTATAGAGTG TTTACCACGC AGGAGCTGGT CCAGGCCTTT 
ACCCATGCCC CCGCTGCCTT GGAAGCCGAC AGAGGTGGCA AGTTTCACAT GGTCGATGGC 
AACGTCACCG GGGAGTTTAC TGACCTGGTC CCCGAGAAAC ACATTGCTAT GAAGTGGAGG 
TTTAAGTCAT GGCCAGAGGG GCACTTTGCC ACCATCACCT TGACCTTCAT TGACAAGAAT 
GGAGAGACAG AGCTGTGCAT GGAAGGCCGT GGCATCCCTG CTCCTGAGGA AGAGCGGACG 
CGGCAAGGCT GGCAGCGGTA CTACTTTGAG GGCATCAAAC AGACCTTTGG CTATGGTGCA 
CGCTTGTTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006515792.1
CDS	501..1112
Translation	MKEDGVKLLREAVGIYISTLKTEFTQGMILPTVNGESVDPVGQPALKTETCKAKSAPSKSQAKPVGVKIPTCKITLKETFLTSPEELYRVFTTQELVQAFTHAPAALEADRGGKFHMVDGNVTGEFTDLVPEKHIAMKWRFKSWPEGHFATITLTFIDKNGETELCMEGRGIPAPEEERTRQGWQRYYFEGIKQTFGYGARLF

Target ORF information:

RefSeq Version	XM_006515729.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus AHA1, activator of heat shock protein ATPase 1 (Ahsa1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006515729.1

ORF Insert Sequence:

ATGAAGGAAG ACGGGGTGAA ACTTCTGAGA GAAGCAGTGG GAATTTACAT CAGCACCCTC 
AAGACAGAGT TTACTCAGGG CATGATCTTG CCCACAGTGA ATGGAGAGTC AGTAGATCCA 
GTGGGCCAGC CAGCACTAAA GACTGAGACT TGCAAGGCTA AGTCTGCTCC TTCAAAAAGC 
CAGGCCAAAC CTGTTGGTGT CAAAATCCCC ACTTGTAAGA TCACCCTTAA AGAAACCTTC 
CTGACCTCCC CAGAGGAGCT CTATAGAGTG TTTACCACGC AGGAGCTGGT CCAGGCCTTT 
ACCCATGCCC CCGCTGCCTT GGAAGCCGAC AGAGGTGGCA AGTTTCACAT GGTCGATGGC 
AACGTCACCG GGGAGTTTAC TGACCTGGTC CCCGAGAAAC ACATTGCTAT GAAGTGGAGG 
TTTAAGTCAT GGCCAGAGGG GCACTTTGCC ACCATCACCT TGACCTTCAT TGACAAGAAT 
GGAGAGACAG AGCTGTGCAT GGAAGGCCGT GGCATCCCTG CTCCTGAGGA AGAGCGGACG 
CGGCAAGGCT GGCAGCGGTA CTACTTTGAG GGCATCAAAC AGACCTTTGG CTATGGTGCA 
CGCTTGTTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ahsa1 ( NM_146036.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_666148.1 Mus musculus AHA1, activator of heat shock protein ATPase 1 (Ahsa1), mRNA.

Price & Availability↑

CloneID	OMu21652
Clone ID Related Accession (Same CDS sequence)	NM_146036.1 , NM_146036.2
Accession Version	NM_146036.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1017bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Mus musculus(house mouse)
Product	activator of 90 kDa heat shock protein ATPase homolog 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC025552.1. Sequence Note: This sequence has been modified as follows: removed 42 bp suspected to be vector contamination from the 3' end. ##Evidence-Data-START## Transcript exon combination :: BC025552.1, AK076069.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCCAAGT GGGGTGAGGG AGACCCACGC TGGATCGTGG AGGAGCGGGC GGACGCCACC 
AACGTCAACA ACTGGCACTG GACAGAGAGA GATGCTTCAA ATTGGTCCAC AGAGAAACTG 
AAAACCCTGT TCCTGGCCGT TCGAGTAGAA AATGAAGAGG GCAAGTGCGA GGTGACCGAA 
GTGAACAAGC TTGATGGGGA GGCATCCATC AACAACAGGA AAGGCAAACT TATCTTCTTC 
TATGAGTGGA CCATCAAACT GAACTGGACA GGTACCTCTA AGTCAGGAGT GCAGTACAAA 
GGACATGTGG AAATCCCCAA TTTGTCTGAT GAAAATAGCG TGGATGAAGT GGAGATTAGT 
GTGAGCCTTG CCAAAGATGA GCCTGACACA AATCTCGTGG CCTTAATGAA GGAAGACGGG 
GTGAAACTTC TGAGAGAAGC AGTGGGAATT TACATCAGCA CCCTCAAGAC AGAGTTTACT 
CAGGGCATGA TCTTGCCCAC AGTGAATGGA GAGTCAGTAG ATCCAGTGGG CCAGCCAGCA 
CTAAAGACTG AGACTTGCAA GGCTAAGTCT GCTCCTTCAA AAAGCCAGGC CAAACCTGTT 
GGTGTCAAAA TCCCCACTTG TAAGATCACC CTTAAAGAAA CCTTCCTGAC CTCCCCAGAG 
GAGCTCTATA GAGTGTTTAC CACGCAGGAG CTGGTCCAGG CCTTTACCCA TGCCCCCGCT 
GCCTTGGAAG CCGACAGAGG TGGCAAGTTT CACATGGTCG ATGGCAACGT CACCGGGGAG 
TTTACTGACC TGGTCCCCGA GAAACACATT GCTATGAAGT GGAGGTTTAA GTCATGGCCA 
GAGGGGCACT TTGCCACCAT CACCTTGACC TTCATTGACA AGAATGGAGA GACAGAGCTG 
TGCATGGAAG GCCGTGGCAT CCCTGCTCCT GAGGAAGAGC GGACGCGGCA AGGCTGGCAG 
CGGTACTACT TTGAGGGCAT CAAACAGACC TTTGGCTATG GTGCACGCTT GTTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_666148.1
CDS	125..1141
Translation	MAKWGEGDPRWIVEERADATNVNNWHWTERDASNWSTEKLKTLFLAVRVENEEGKCEVTEVNKLDGEASINNRKGKLIFFYEWTIKLNWTGTSKSGVQYKGHVEIPNLSDENSVDEVEISVSLAKDEPDTNLVALMKEDGVKLLREAVGIYISTLKTEFTQGMILPTVNGESVDPVGQPALKTETCKAKSAPSKSQAKPVGVKIPTCKITLKETFLTSPEELYRVFTTQELVQAFTHAPAALEADRGGKFHMVDGNVTGEFTDLVPEKHIAMKWRFKSWPEGHFATITLTFIDKNGETELCMEGRGIPAPEEERTRQGWQRYYFEGIKQTFGYGARLF

Target ORF information:

RefSeq Version	NM_146036.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus AHA1, activator of heat shock protein ATPase 1 (Ahsa1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_146036.1

ORF Insert Sequence:

ATGGCCAAGT GGGGTGAGGG AGACCCACGC TGGATCGTGG AGGAGCGGGC GGACGCCACC 
AACGTCAACA ACTGGCACTG GACAGAGAGA GATGCTTCAA ATTGGTCCAC AGAGAAACTG 
AAAACCCTGT TCCTGGCCGT TCGAGTAGAA AATGAAGAGG GCAAGTGCGA GGTGACCGAA 
GTGAACAAGC TTGATGGGGA GGCATCCATC AACAACAGGA AAGGCAAACT TATCTTCTTC 
TATGAGTGGA CCATCAAACT GAACTGGACA GGTACCTCTA AGTCAGGAGT GCAGTACAAA 
GGACATGTGG AAATCCCCAA TTTGTCTGAT GAAAATAGCG TGGATGAAGT GGAGATTAGT 
GTGAGCCTTG CCAAAGATGA GCCTGACACA AATCTCGTGG CCTTAATGAA GGAAGACGGG 
GTGAAACTTC TGAGAGAAGC AGTGGGAATT TACATCAGCA CCCTCAAGAC AGAGTTTACT 
CAGGGCATGA TCTTGCCCAC AGTGAATGGA GAGTCAGTAG ATCCAGTGGG CCAGCCAGCA 
CTAAAGACTG AGACTTGCAA GGCTAAGTCT GCTCCTTCAA AAAGCCAGGC CAAACCTGTT 
GGTGTCAAAA TCCCCACTTG TAAGATCACC CTTAAAGAAA CCTTCCTGAC CTCCCCAGAG 
GAGCTCTATA GAGTGTTTAC CACGCAGGAG CTGGTCCAGG CCTTTACCCA TGCCCCCGCT 
GCCTTGGAAG CCGACAGAGG TGGCAAGTTT CACATGGTCG ATGGCAACGT CACCGGGGAG 
TTTACTGACC TGGTCCCCGA GAAACACATT GCTATGAAGT GGAGGTTTAA GTCATGGCCA 
GAGGGGCACT TTGCCACCAT CACCTTGACC TTCATTGACA AGAATGGAGA GACAGAGCTG 
TGCATGGAAG GCCGTGGCAT CCCTGCTCCT GAGGAAGAGC GGACGCGGCA AGGCTGGCAG 
CGGTACTACT TTGAGGGCAT CAAACAGACC TTTGGCTATG GTGCACGCTT GTTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ahsa1 ( NM_146036.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_666148.1 Mus musculus AHA1, activator of heat shock protein ATPase 1 (Ahsa1), mRNA.

Price & Availability↑

CloneID	OMu21652
Clone ID Related Accession (Same CDS sequence)	NM_146036.1 , NM_146036.2
Accession Version	NM_146036.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1017bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-23
Organism	Mus musculus(house mouse)
Product	activator of 90 kDa heat shock protein ATPase homolog 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC151967.6. On Aug 15, 2018 this sequence version replaced NM_146036.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC025552.1, SRR5286963.62062.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCCAAGT GGGGTGAGGG AGACCCACGC TGGATCGTGG AGGAGCGGGC GGACGCCACC 
AACGTCAACA ACTGGCACTG GACAGAGAGA GATGCTTCAA ATTGGTCCAC AGAGAAACTG 
AAAACCCTGT TCCTGGCCGT TCGAGTAGAA AATGAAGAGG GCAAGTGCGA GGTGACCGAA 
GTGAACAAGC TTGATGGGGA GGCATCCATC AACAACAGGA AAGGCAAACT TATCTTCTTC 
TATGAGTGGA CCATCAAACT GAACTGGACA GGTACCTCTA AGTCAGGAGT GCAGTACAAA 
GGACATGTGG AAATCCCCAA TTTGTCTGAT GAAAATAGCG TGGATGAAGT GGAGATTAGT 
GTGAGCCTTG CCAAAGATGA GCCTGACACA AATCTCGTGG CCTTAATGAA GGAAGACGGG 
GTGAAACTTC TGAGAGAAGC AGTGGGAATT TACATCAGCA CCCTCAAGAC AGAGTTTACT 
CAGGGCATGA TCTTGCCCAC AGTGAATGGA GAGTCAGTAG ATCCAGTGGG CCAGCCAGCA 
CTAAAGACTG AGACTTGCAA GGCTAAGTCT GCTCCTTCAA AAAGCCAGGC CAAACCTGTT 
GGTGTCAAAA TCCCCACTTG TAAGATCACC CTTAAAGAAA CCTTCCTGAC CTCCCCAGAG 
GAGCTCTATA GAGTGTTTAC CACGCAGGAG CTGGTCCAGG CCTTTACCCA TGCCCCCGCT 
GCCTTGGAAG CCGACAGAGG TGGCAAGTTT CACATGGTCG ATGGCAACGT CACCGGGGAG 
TTTACTGACC TGGTCCCCGA GAAACACATT GCTATGAAGT GGAGGTTTAA GTCATGGCCA 
GAGGGGCACT TTGCCACCAT CACCTTGACC TTCATTGACA AGAATGGAGA GACAGAGCTG 
TGCATGGAAG GCCGTGGCAT CCCTGCTCCT GAGGAAGAGC GGACGCGGCA AGGCTGGCAG 
CGGTACTACT TTGAGGGCAT CAAACAGACC TTTGGCTATG GTGCACGCTT GTTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_666148.1
CDS	115..1131
Translation	MAKWGEGDPRWIVEERADATNVNNWHWTERDASNWSTEKLKTLFLAVRVENEEGKCEVTEVNKLDGEASINNRKGKLIFFYEWTIKLNWTGTSKSGVQYKGHVEIPNLSDENSVDEVEISVSLAKDEPDTNLVALMKEDGVKLLREAVGIYISTLKTEFTQGMILPTVNGESVDPVGQPALKTETCKAKSAPSKSQAKPVGVKIPTCKITLKETFLTSPEELYRVFTTQELVQAFTHAPAALEADRGGKFHMVDGNVTGEFTDLVPEKHIAMKWRFKSWPEGHFATITLTFIDKNGETELCMEGRGIPAPEEERTRQGWQRYYFEGIKQTFGYGARLF

Target ORF information:

RefSeq Version	NM_146036.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus AHA1, activator of heat shock protein ATPase 1 (Ahsa1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_146036.2

ORF Insert Sequence:

ATGGCCAAGT GGGGTGAGGG AGACCCACGC TGGATCGTGG AGGAGCGGGC GGACGCCACC 
AACGTCAACA ACTGGCACTG GACAGAGAGA GATGCTTCAA ATTGGTCCAC AGAGAAACTG 
AAAACCCTGT TCCTGGCCGT TCGAGTAGAA AATGAAGAGG GCAAGTGCGA GGTGACCGAA 
GTGAACAAGC TTGATGGGGA GGCATCCATC AACAACAGGA AAGGCAAACT TATCTTCTTC 
TATGAGTGGA CCATCAAACT GAACTGGACA GGTACCTCTA AGTCAGGAGT GCAGTACAAA 
GGACATGTGG AAATCCCCAA TTTGTCTGAT GAAAATAGCG TGGATGAAGT GGAGATTAGT 
GTGAGCCTTG CCAAAGATGA GCCTGACACA AATCTCGTGG CCTTAATGAA GGAAGACGGG 
GTGAAACTTC TGAGAGAAGC AGTGGGAATT TACATCAGCA CCCTCAAGAC AGAGTTTACT 
CAGGGCATGA TCTTGCCCAC AGTGAATGGA GAGTCAGTAG ATCCAGTGGG CCAGCCAGCA 
CTAAAGACTG AGACTTGCAA GGCTAAGTCT GCTCCTTCAA AAAGCCAGGC CAAACCTGTT 
GGTGTCAAAA TCCCCACTTG TAAGATCACC CTTAAAGAAA CCTTCCTGAC CTCCCCAGAG 
GAGCTCTATA GAGTGTTTAC CACGCAGGAG CTGGTCCAGG CCTTTACCCA TGCCCCCGCT 
GCCTTGGAAG CCGACAGAGG TGGCAAGTTT CACATGGTCG ATGGCAACGT CACCGGGGAG 
TTTACTGACC TGGTCCCCGA GAAACACATT GCTATGAAGT GGAGGTTTAA GTCATGGCCA 
GAGGGGCACT TTGCCACCAT CACCTTGACC TTCATTGACA AGAATGGAGA GACAGAGCTG 
TGCATGGAAG GCCGTGGCAT CCCTGCTCCT GAGGAAGAGC GGACGCGGCA AGGCTGGCAG 
CGGTACTACT TTGAGGGCAT CAAACAGACC TTTGGCTATG GTGCACGCTT GTTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ahsa1 ( XM_006515729.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006515792.1 Mus musculus AHA1, activator of heat shock protein ATPase 1 (Ahsa1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu47744
Clone ID Related Accession (Same CDS sequence)	XM_006515729.2 , XM_006515729.1
Accession Version	XM_006515729.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 612bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	activator of 90 kDa heat shock protein ATPase homolog 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006515729.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGGAAG ACGGGGTGAA ACTTCTGAGA GAAGCAGTGG GAATTTACAT CAGCACCCTC 
AAGACAGAGT TTACTCAGGG CATGATCTTG CCCACAGTGA ATGGAGAGTC AGTAGATCCA 
GTGGGCCAGC CAGCACTAAA GACTGAGACT TGCAAGGCTA AGTCTGCTCC TTCAAAAAGC 
CAGGCCAAAC CTGTTGGTGT CAAAATCCCC ACTTGTAAGA TCACCCTTAA AGAAACCTTC 
CTGACCTCCC CAGAGGAGCT CTATAGAGTG TTTACCACGC AGGAGCTGGT CCAGGCCTTT 
ACCCATGCCC CCGCTGCCTT GGAAGCCGAC AGAGGTGGCA AGTTTCACAT GGTCGATGGC 
AACGTCACCG GGGAGTTTAC TGACCTGGTC CCCGAGAAAC ACATTGCTAT GAAGTGGAGG 
TTTAAGTCAT GGCCAGAGGG GCACTTTGCC ACCATCACCT TGACCTTCAT TGACAAGAAT 
GGAGAGACAG AGCTGTGCAT GGAAGGCCGT GGCATCCCTG CTCCTGAGGA AGAGCGGACG 
CGGCAAGGCT GGCAGCGGTA CTACTTTGAG GGCATCAAAC AGACCTTTGG CTATGGTGCA 
CGCTTGTTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006515792.1
CDS	570..1181
Translation	MKEDGVKLLREAVGIYISTLKTEFTQGMILPTVNGESVDPVGQPALKTETCKAKSAPSKSQAKPVGVKIPTCKITLKETFLTSPEELYRVFTTQELVQAFTHAPAALEADRGGKFHMVDGNVTGEFTDLVPEKHIAMKWRFKSWPEGHFATITLTFIDKNGETELCMEGRGIPAPEEERTRQGWQRYYFEGIKQTFGYGARLF

Target ORF information:

RefSeq Version	XM_006515729.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus AHA1, activator of heat shock protein ATPase 1 (Ahsa1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006515729.2

ORF Insert Sequence:

ATGAAGGAAG ACGGGGTGAA ACTTCTGAGA GAAGCAGTGG GAATTTACAT CAGCACCCTC 
AAGACAGAGT TTACTCAGGG CATGATCTTG CCCACAGTGA ATGGAGAGTC AGTAGATCCA 
GTGGGCCAGC CAGCACTAAA GACTGAGACT TGCAAGGCTA AGTCTGCTCC TTCAAAAAGC 
CAGGCCAAAC CTGTTGGTGT CAAAATCCCC ACTTGTAAGA TCACCCTTAA AGAAACCTTC 
CTGACCTCCC CAGAGGAGCT CTATAGAGTG TTTACCACGC AGGAGCTGGT CCAGGCCTTT 
ACCCATGCCC CCGCTGCCTT GGAAGCCGAC AGAGGTGGCA AGTTTCACAT GGTCGATGGC 
AACGTCACCG GGGAGTTTAC TGACCTGGTC CCCGAGAAAC ACATTGCTAT GAAGTGGAGG 
TTTAAGTCAT GGCCAGAGGG GCACTTTGCC ACCATCACCT TGACCTTCAT TGACAAGAAT 
GGAGAGACAG AGCTGTGCAT GGAAGGCCGT GGCATCCCTG CTCCTGAGGA AGAGCGGACG 
CGGCAAGGCT GGCAGCGGTA CTACTTTGAG GGCATCAAAC AGACCTTTGG CTATGGTGCA 
CGCTTGTTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients.
The EMBO journal36(24)3650-3665(2017 12)
Woodford MR,Sager RA,Marris E,Dunn DM,Blanden AR,Murphy RL,Rensing N,Shapiro O,Panaretou B,Prodromou C,Loh SN,Gutmann DH,Bourboulia D,Bratslavsky G,Wong M,Mollapour M

Modulation of the cochaperone AHA1 regulates heat-shock protein 90 and endothelial NO synthase activation by vascular endothelial growth factor.
Arteriosclerosis, thrombosis, and vascular biology32(10)2484-92(2012 Oct)
Desjardins F,Delisle C,Gratton JP

Dynamic tyrosine phosphorylation modulates cycling of the HSP90-P50(CDC37)-AHA1 chaperone machine.
Molecular cell47(3)434-43(2012 Aug)
Xu W,Mollapour M,Prodromou C,Wang S,Scroggins BT,Palchick Z,Beebe K,Siderius M,Lee MJ,Couvillon A,Trepel JB,Miyata Y,Matts R,Neckers L

An interaction network predicted from public data as a discovery tool: application to the Hsp90 molecular chaperone machine.
PloS one6(10)e26044(2011)
Echeverr?a PC,Bernthaler A,Dupuis P,Mayer B,Picard D

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Nucleic acids research31(1)278-81(2003 Jan)
Stryke D,Kawamoto M,Huang CC,Johns SJ,King LA,Harper CA,Meng EC,Lee RE,Yee A,L'Italien L,Chuang PT,Young SG,Skarnes WC,Babbitt PC,Ferrin TE

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Ahsa1 cDNA ORF clone, Mus musculus(house mouse)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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