Entpd3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Entpd3
Entrez Gene ID	215446
Full Name	ectonucleoside triphosphate diphosphohydrolase 3
Synonyms	Cd39l3,HB6,NTPDase-3
General protein information	Preferred Names ectonucleoside triphosphate diphosphohydrolase 3 Names ectonucleoside triphosphate diphosphohydrolase 3 CD39 antigen-like 3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9\|9 F4

mRNA and Protein(s)

mRNA	Protein	Name
NM_178676.5	NP_848791.3	ectonucleoside triphosphate diphosphohydrolase 3
NM_178676.4	NP_848791.2	ectonucleoside triphosphate diphosphohydrolase 3

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ENTPD3	NP_001017935.1
Rattus norvegicus (Norway rat)	Entpd3	NP_835207.1
Danio rerio (zebrafish)	entpd3	NP_001077050.1
	ENTPD3	XP_001110787.1
Xenopus tropicalis (tropical clawed frog)	entpd3	NP_001096408.1
Homo sapiens (human)	ENTPD3	NP_001239.2
Mus musculus (house mouse)	Entpd3	NP_848791.2
Pan troglodytes (chimpanzee)	ENTPD3	XP_001135726.1
Canis lupus familiaris (dog)	ENTPD3	XP_542723.3
Gallus gallus (chicken)	ENTPD3	XP_426007.3

Gene Ontology
Bibliography

Related articles in PubMed

Expression of Ecto-nucleoside Triphosphate Diphosphohydrolases-2 and -3 in the Enteric Nervous System Affects Inflammation in Experimental Colitis and Crohn's Disease.
Feldbr?gge L, Moss AC, Yee EU, Csizmadia E, Mitsuhashi S, Longhi MS, Sandhu B, Stephan H, Wu Y, Cheifetz AS, M?ller CE, S?vigny J, Robson SC, Jiang ZG
Journal of Crohn's & colitis11(9)1113-1123(2017 Sep)

Increased expression of NTPDases 2 and 3 in mesenteric endothelial cells during schistosomiasis favors leukocyte adhesion through P2Y1 receptors.
Oliveira SD, Oliveira NF, Meyer-Fernandes JR, Savio LE, Ornelas FG, Ferreira ZS, Coutinho-Silva R, Silva CL
Vascular pharmacology8266-72(2016 Jul)

Neuronal NTPDase3 Mediates Extracellular ATP Degradation in Trigeminal Nociceptive Pathway.
Ma L, Trinh T, Ren Y, Dirksen RT, Liu X
PloS one11(10)e0164028(2016)

NTPDase3 and ecto-5'-nucleotidase/CD73 are differentially expressed during mouse bladder cancer progression.
Rockenbach L, Braganhol E, Dietrich F, Figueir? F, Pugliese M, Edelweiss MI, Morrone FB, S?vigny J, Battastini AM
Purinergic signalling10(3)421-30(2014 Sep)

Deletion of ENTPD3 does not impair nucleotide hydrolysis in primary somatosensory neurons or spinal cord.
McCoy E, Street S, Taylor-Blake B, Yi J, Edwards M, Wightman M, Zylka M
F1000Research3163(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Mesenteric endothelial cells are primed by schistosomiasis to a pro-inflammatory phenotype characterized by an increased expression of NTPDases 2 and 3, favoring ADP accumulation and mononuclear cell adhesion, possibly contributing to mesenteric inflammation and schistosomiasis morbidity via P2Y1 receptor signaling.
Title: Increased expression of NTPDases 2 and 3 in mesenteric endothelial cells during schistosomiasis favors leukocyte adhesion through P2Y1 receptors.

Results identified the expression of ecto-NTPDase3 in trigeminal nociceptive neurons and demonstrated the presence of functional ecto-ATPase activity in trigeminal nerves and established that ecto-NTPDase3mediates extracellularATP degradation in the nociceptive lamina on the brainstem.
Title: Neuronal NTPDase3 Mediates Extracellular ATP Degradation in Trigeminal Nociceptive Pathway.

In bladder cancer disease progression there was a weak immunostaining to NTPDase in bladder samples.
Title: NTPDase3 and ecto-5'-nucleotidase/CD73 are differentially expressed during mouse bladder cancer progression.

NTPDase3 is the major ectonucleotidase in pancreatic beta-cells in multiple species and modulates insulin secretion by controlling activation of purinergic receptors.
Title: Ectonucleotidase NTPDase3 is abundant in pancreatic ?-cells and regulates glucose-induced insulin secretion.

The results of this study proposeed that NTPDase3 is a key regulator of nociceptive signaling that also makes an unexpected contribution to innocuous tactile sensation.
Title: Distribution of ecto-nucleotidases in mouse sensory circuits suggests roles for nucleoside triphosphate diphosphohydrolase-3 in nociception and mechanoreception.

The following Entpd3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Entpd3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu07540	NM_178676.4 Latest version!	Mus musculus ectonucleoside triphosphate diphosphohydrolase 3 (Entpd3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$314.30 $449.00
OMu84090	NM_178676.5 Latest version!	Mus musculus ectonucleoside triphosphate diphosphohydrolase 3 (Entpd3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Entpd3 ( NM_178676.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_848791.2 Mus musculus ectonucleoside triphosphate diphosphohydrolase 3 (Entpd3), mRNA.

Price & Availability↑

CloneID	OMu07540
Clone ID Related Accession (Same CDS sequence)	NM_178676.4
Accession Version	NM_178676.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1590bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-06-25
Organism	Mus musculus(house mouse)
Product	ectonucleoside triphosphate diphosphohydrolase 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB580245.1, AK046218.1, AC123708.17 and AI854406.1. On Aug 8, 2009 this sequence version replaced NM_178676.3. ##Evidence-Data-START## Transcript exon combination :: AK046218.1, AK032057.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTTACCG TGATGACCCG CCAGCCATGT GAACAGGCAG GCTTCAGGGC CCTCTCGAGG 
ACTCCTGCCA TCGTCACCTT GGTGGTCCTG CTTGTGAGCA TTGTGGTACT TGTGACACTT 
ACACTCATCC AGATCCGCCA CCCACAGGTT CTCCCTCCGG GGCTGAAGTA TGGCGTCGTG 
CTCGATGCTG GCTCTTCCAG AACCACTGTC TACGTGTATC AGTGGCCGGC AGAGAAGGAG 
AATAACACAG GAGTGGTCAG CCAAACTTTC AGATGCAGTG TGAAAGGCTC TGGGATCTCC 
AGCTATGAGA ATAACCCCCA AGATGCCCCC AAAGCCTTTG AGGACTGTAT ACTAAAGTTC 
AAGGAACAGG TCCCAGAGCA CCTCCACGGA TCCACCCGCA TTTACCTGGG AGCTACAGCT 
GGGATGCGCT TGCTGAGGTT GCAGAATGAG ACAGCAGCTC GTGAAGTCCT TGAGAGCATC 
CAAAGCTACT TCAAGTCCCA GCCTTTTGAT TTTAGGGGTG CTCAAATCAT TTCTGGGCAA 
GAGGAAGGGG TGTATGGATG GATTACAGCC AACTATATAA TGGGAAATTT CCTGGAGAAG 
AACCTGTGGC ACATGTGGGT GCACCCGCAC GGAGTCGACA CCACAGGAGC CCTGGATTTA 
GGTGGCGCCT CCACCCAGAT ATCCTTCGTG GCCGGGGAGA AGATGGAGCC GAACGCCAGC 
GACACGGTGC AGGTGTCTCT GTACGGCTAC ACGTACACTC TCTACACACA CAGCTTCCAG 
TGCTATGGCC AGAATGAAGC AGAGAAGAAG TTCCTGGCCA TGCTTCTACA GAGCCCTTCC 
ACGGAAGCCA ACATCAGCAA CCCCTGCTAC CCTCAGGGCT ACAGTACCGC CTTCACCTTG 
GGCCATGTGT TTGGCAGCCT GTGCACAGAG AAGCAGAGGC CAGAGAGCTA CAACTCCAGT 
AAGAGCGTCA CCTTCATGGG AACTGGTGAC CCACGACTGT GCAGGGAGAA GGTGGCTTCT 
GTGTTTGACT TCAATGCTTG CCAAGAGCAA GACGCCTGTT CCTTTGATGG CATTTACCAG 
CCCAAGGTTC AAGGGCCATT TGTGGCGTTC GCAGGCTTCT ACTACACAGC CAGTGCGCTA 
AACCTCTCAG GAAGCTTCTC CCTTACCTCC TTCAATGACA GCAGCTGGGA CTTCTGCAGA 
CACACTTGGA GCGAGCTCCC AGCCCTGCTC TCCAGATTTG ATGAGACGTA TGCCCGGTCC 
TACTGCTTCT CAGCCCACTA CATCTACCAC TTGCTCGTAA ATGGATACAA GTTCACTGAG 
GAGACTTGGC CTCAGATACG CTTTGAAAAA GAAGTGGGGA ACAGCAGCAT CGCCTGGTCC 
CTTGGCTACA TGCTCAGCTT GACCAACCAG ATCCCAGCTG GAAGTCCCCT GATCCATCTA 
CCCATACAGC CACCGGTGTT TATGGGAGTC CTGGCCTTCT TCACAGCTAT CGCCTTGCTG 
TGCCTGGCAT TTCTTCTGTA TCTATGTTCA TCATTCAGGA CAAAGGAGCG CTCTGAGAAT 
GCCTTCGACC AAGCAGTGGA TTCTGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_848791.2
CDS	79..1668
Translation	MFTVMTRQPCEQAGFRALSRTPAIVTLVVLLVSIVVLVTLTLIQIRHPQVLPPGLKYGVVLDAGSSRTTVYVYQWPAEKENNTGVVSQTFRCSVKGSGISSYENNPQDAPKAFEDCILKFKEQVPEHLHGSTRIYLGATAGMRLLRLQNETAAREVLESIQSYFKSQPFDFRGAQIISGQEEGVYGWITANYIMGNFLEKNLWHMWVHPHGVDTTGALDLGGASTQISFVAGEKMEPNASDTVQVSLYGYTYTLYTHSFQCYGQNEAEKKFLAMLLQSPSTEANISNPCYPQGYSTAFTLGHVFGSLCTEKQRPESYNSSKSVTFMGTGDPRLCREKVASVFDFNACQEQDACSFDGIYQPKVQGPFVAFAGFYYTASALNLSGSFSLTSFNDSSWDFCRHTWSELPALLSRFDETYARSYCFSAHYIYHLLVNGYKFTEETWPQIRFEKEVGNSSIAWSLGYMLSLTNQIPAGSPLIHLPIQPPVFMGVLAFFTAIALLCLAFLLYLCSSFRTKERSENAFDQAVDSD

Target ORF information:

RefSeq Version	NM_178676.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus ectonucleoside triphosphate diphosphohydrolase 3 (Entpd3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_178676.4

ORF Insert Sequence:

ATGTTTACCG TGATGACCCG CCAGCCATGT GAACAGGCAG GCTTCAGGGC CCTCTCGAGG 
ACTCCTGCCA TCGTCACCTT GGTGGTCCTG CTTGTGAGCA TTGTGGTACT TGTGACACTT 
ACACTCATCC AGATCCGCCA CCCACAGGTT CTCCCTCCGG GGCTGAAGTA TGGCGTCGTG 
CTCGATGCTG GCTCTTCCAG AACCACTGTC TACGTGTATC AGTGGCCGGC AGAGAAGGAG 
AATAACACAG GAGTGGTCAG CCAAACTTTC AGATGCAGTG TGAAAGGCTC TGGGATCTCC 
AGCTATGAGA ATAACCCCCA AGATGCCCCC AAAGCCTTTG AGGACTGTAT ACTAAAGTTC 
AAGGAACAGG TCCCAGAGCA CCTCCACGGA TCCACCCGCA TTTACCTGGG AGCTACAGCT 
GGGATGCGCT TGCTGAGGTT GCAGAATGAG ACAGCAGCTC GTGAAGTCCT TGAGAGCATC 
CAAAGCTACT TCAAGTCCCA GCCTTTTGAT TTTAGGGGTG CTCAAATCAT TTCTGGGCAA 
GAGGAAGGGG TGTATGGATG GATTACAGCC AACTATATAA TGGGAAATTT CCTGGAGAAG 
AACCTGTGGC ACATGTGGGT GCACCCGCAC GGAGTCGACA CCACAGGAGC CCTGGATTTA 
GGTGGCGCCT CCACCCAGAT ATCCTTCGTG GCCGGGGAGA AGATGGAGCC GAACGCCAGC 
GACACGGTGC AGGTGTCTCT GTACGGCTAC ACGTACACTC TCTACACACA CAGCTTCCAG 
TGCTATGGCC AGAATGAAGC AGAGAAGAAG TTCCTGGCCA TGCTTCTACA GAGCCCTTCC 
ACGGAAGCCA ACATCAGCAA CCCCTGCTAC CCTCAGGGCT ACAGTACCGC CTTCACCTTG 
GGCCATGTGT TTGGCAGCCT GTGCACAGAG AAGCAGAGGC CAGAGAGCTA CAACTCCAGT 
AAGAGCGTCA CCTTCATGGG AACTGGTGAC CCACGACTGT GCAGGGAGAA GGTGGCTTCT 
GTGTTTGACT TCAATGCTTG CCAAGAGCAA GACGCCTGTT CCTTTGATGG CATTTACCAG 
CCCAAGGTTC AAGGGCCATT TGTGGCGTTC GCAGGCTTCT ACTACACAGC CAGTGCGCTA 
AACCTCTCAG GAAGCTTCTC CCTTACCTCC TTCAATGACA GCAGCTGGGA CTTCTGCAGA 
CACACTTGGA GCGAGCTCCC AGCCCTGCTC TCCAGATTTG ATGAGACGTA TGCCCGGTCC 
TACTGCTTCT CAGCCCACTA CATCTACCAC TTGCTCGTAA ATGGATACAA GTTCACTGAG 
GAGACTTGGC CTCAGATACG CTTTGAAAAA GAAGTGGGGA ACAGCAGCAT CGCCTGGTCC 
CTTGGCTACA TGCTCAGCTT GACCAACCAG ATCCCAGCTG GAAGTCCCCT GATCCATCTA 
CCCATACAGC CACCGGTGTT TATGGGAGTC CTGGCCTTCT TCACAGCTAT CGCCTTGCTG 
TGCCTGGCAT TTCTTCTGTA TCTATGTTCA TCATTCAGGA CAAAGGAGCG CTCTGAGAAT 
GCCTTCGACC AAGCAGTGGA TTCTGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Entpd3 ( NM_178676.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_848791.3 Mus musculus ectonucleoside triphosphate diphosphohydrolase 3 (Entpd3), mRNA.

Price & Availability↑

CloneID	OMu84090
Clone ID Related Accession (Same CDS sequence)	NM_178676.5
Accession Version	NM_178676.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1590bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-12
Organism	Mus musculus(house mouse)
Product	ectonucleoside triphosphate diphosphohydrolase 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB580245.1, AK046218.1, BY595885.1 and AI854406.1. On Aug 21, 2018 this sequence version replaced NM_178676.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK046218.1, AK032057.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTTACCG TGATGACCCG CCAGCCATGT GAACAGGCAG GCTTCAGGGC CCTCTCGAGG 
ACTCCTGCCA TCGTCACCTT GGTGGTCCTG CTTGTGAGCA TTGTGGTACT TGTGACACTT 
ACACTCATCC AGATCCGCCA CCCACAGGTT CTCCCTCCGG GGCTGAAGTA TGGCGTCGTG 
CTCGATGCTG GCTCTTCCAG AACCACTGTC TACGTGTATC AGTGGCCGGC AGAGAAGGAG 
AATAACACAG GAGTGGTCAG CCAAACTTTC AGATGCAGTG TGAAAGGCTC TGGGATCTCC 
AGCTATGAGA ATAACCCCCA AGATGCCCCC AAAGCCTTTG AGGACTGTAT ACTAAAGGTC 
AAGGAACAGG TCCCAGAGCA CCTCCACGGA TCCACCCGCA TTTACCTGGG AGCTACAGCT 
GGGATGCGCT TGCTGAGGTT GCAGAATGAG ACAGCAGCTC GTGAAGTCCT TGAGAGCATC 
CAAAGCTACT TCAAGTCCCA GCCTTTTGAT TTTAGGGGTG CTCAAATCAT TTCTGGGCAA 
GAGGAAGGGG TGTATGGATG GATTACAGCC AACTATATAA TGGGAAATTT CCTGGAGAAG 
AACCTGTGGC ACATGTGGGT GCACCCGCAC GGAGTCGACA CCACAGGAGC CCTGGATTTA 
GGTGGCGCCT CCACCCAGAT ATCCTTCGTG GCCGGGGAGA AGATGGAGCC GAACGCCAGC 
GACACGGTGC AGGTGTCTCT GTACGGCTAC ACGTACACTC TCTACACACA CAGCTTCCAG 
TGCTATGGCC AGAATGAAGC AGAGAAGAAG TTCCTGGCCA TGCTTCTACA GAGCCCTTCC 
ACGGAAGCCA ACATCAGCAA CCCCTGCTAC CCTCAGGGCT ACAGTACCGC CTTCACCTTG 
GGCCATGTGT TTGGCAGCCT GTGCACAGAG AAGCAGAGGC CAGAGAGCTA CAACTCCAGT 
AAGAGCGTCA CCTTCATGGG AACTGGTGAC CCACGACTGT GCAGGGAGAA GGTGGCTTCT 
GTGTTTGACT TCAATGCTTG CCAAGAGCAA GACGCCTGTT CCTTTGATGG CATTTACCAG 
CCCAAGGTTC AAGGGCCATT TGTGGCGTTC GCAGGCTTCT ACTACACAGC CAGTGCGCTA 
AACCTCTCAG GAAGCTTCTC CCTTACCTCC TTCAATGACA GCAGCTGGGA CTTCTGCAGA 
CACACTTGGA GCGAGCTCCC AGCCCTGCTC TCCAGATTTG ATGAGACGTA TGCCCGGTCC 
TACTGCTTCT CAGCCCACTA CATCTACCAC TTGCTCGTAA ATGGATACAA GTTCACTGAG 
GAGACTTGGC CTCAGATACG CTTTGAAAAA GAAGTGGGGA ACAGCAGCAT CGCCTGGTCC 
CTTGGCTACA TGCTCAGCTT GACCAACCAG ATCCCAGCTG GAAGTCCCCT GATCCATCTA 
CCCATACAGC CACCGGTGTT TATGGGAGTC CTGGCCTTCT TCACAGCTAT CGCCTTGCTG 
TGCCTGGCAT TTCTTCTGTA TCTATGTTCA TCATTCAGGA CAAAGGAGCG CTCTGAGAAT 
GCCTTCGACC AAGCAGTGGA TTCTGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_848791.3
CDS	79..1668
Translation	MFTVMTRQPCEQAGFRALSRTPAIVTLVVLLVSIVVLVTLTLIQIRHPQVLPPGLKYGVVLDAGSSRTTVYVYQWPAEKENNTGVVSQTFRCSVKGSGISSYENNPQDAPKAFEDCILKVKEQVPEHLHGSTRIYLGATAGMRLLRLQNETAAREVLESIQSYFKSQPFDFRGAQIISGQEEGVYGWITANYIMGNFLEKNLWHMWVHPHGVDTTGALDLGGASTQISFVAGEKMEPNASDTVQVSLYGYTYTLYTHSFQCYGQNEAEKKFLAMLLQSPSTEANISNPCYPQGYSTAFTLGHVFGSLCTEKQRPESYNSSKSVTFMGTGDPRLCREKVASVFDFNACQEQDACSFDGIYQPKVQGPFVAFAGFYYTASALNLSGSFSLTSFNDSSWDFCRHTWSELPALLSRFDETYARSYCFSAHYIYHLLVNGYKFTEETWPQIRFEKEVGNSSIAWSLGYMLSLTNQIPAGSPLIHLPIQPPVFMGVLAFFTAIALLCLAFLLYLCSSFRTKERSENAFDQAVDSD

Target ORF information:

RefSeq Version	NM_178676.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus ectonucleoside triphosphate diphosphohydrolase 3 (Entpd3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_178676.5

ORF Insert Sequence:

ATGTTTACCG TGATGACCCG CCAGCCATGT GAACAGGCAG GCTTCAGGGC CCTCTCGAGG 
ACTCCTGCCA TCGTCACCTT GGTGGTCCTG CTTGTGAGCA TTGTGGTACT TGTGACACTT 
ACACTCATCC AGATCCGCCA CCCACAGGTT CTCCCTCCGG GGCTGAAGTA TGGCGTCGTG 
CTCGATGCTG GCTCTTCCAG AACCACTGTC TACGTGTATC AGTGGCCGGC AGAGAAGGAG 
AATAACACAG GAGTGGTCAG CCAAACTTTC AGATGCAGTG TGAAAGGCTC TGGGATCTCC 
AGCTATGAGA ATAACCCCCA AGATGCCCCC AAAGCCTTTG AGGACTGTAT ACTAAAGGTC 
AAGGAACAGG TCCCAGAGCA CCTCCACGGA TCCACCCGCA TTTACCTGGG AGCTACAGCT 
GGGATGCGCT TGCTGAGGTT GCAGAATGAG ACAGCAGCTC GTGAAGTCCT TGAGAGCATC 
CAAAGCTACT TCAAGTCCCA GCCTTTTGAT TTTAGGGGTG CTCAAATCAT TTCTGGGCAA 
GAGGAAGGGG TGTATGGATG GATTACAGCC AACTATATAA TGGGAAATTT CCTGGAGAAG 
AACCTGTGGC ACATGTGGGT GCACCCGCAC GGAGTCGACA CCACAGGAGC CCTGGATTTA 
GGTGGCGCCT CCACCCAGAT ATCCTTCGTG GCCGGGGAGA AGATGGAGCC GAACGCCAGC 
GACACGGTGC AGGTGTCTCT GTACGGCTAC ACGTACACTC TCTACACACA CAGCTTCCAG 
TGCTATGGCC AGAATGAAGC AGAGAAGAAG TTCCTGGCCA TGCTTCTACA GAGCCCTTCC 
ACGGAAGCCA ACATCAGCAA CCCCTGCTAC CCTCAGGGCT ACAGTACCGC CTTCACCTTG 
GGCCATGTGT TTGGCAGCCT GTGCACAGAG AAGCAGAGGC CAGAGAGCTA CAACTCCAGT 
AAGAGCGTCA CCTTCATGGG AACTGGTGAC CCACGACTGT GCAGGGAGAA GGTGGCTTCT 
GTGTTTGACT TCAATGCTTG CCAAGAGCAA GACGCCTGTT CCTTTGATGG CATTTACCAG 
CCCAAGGTTC AAGGGCCATT TGTGGCGTTC GCAGGCTTCT ACTACACAGC CAGTGCGCTA 
AACCTCTCAG GAAGCTTCTC CCTTACCTCC TTCAATGACA GCAGCTGGGA CTTCTGCAGA 
CACACTTGGA GCGAGCTCCC AGCCCTGCTC TCCAGATTTG ATGAGACGTA TGCCCGGTCC 
TACTGCTTCT CAGCCCACTA CATCTACCAC TTGCTCGTAA ATGGATACAA GTTCACTGAG 
GAGACTTGGC CTCAGATACG CTTTGAAAAA GAAGTGGGGA ACAGCAGCAT CGCCTGGTCC 
CTTGGCTACA TGCTCAGCTT GACCAACCAG ATCCCAGCTG GAAGTCCCCT GATCCATCTA 
CCCATACAGC CACCGGTGTT TATGGGAGTC CTGGCCTTCT TCACAGCTAT CGCCTTGCTG 
TGCCTGGCAT TTCTTCTGTA TCTATGTTCA TCATTCAGGA CAAAGGAGCG CTCTGAGAAT 
GCCTTCGACC AAGCAGTGGA TTCTGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression of Ecto-nucleoside Triphosphate Diphosphohydrolases-2 and -3 in the Enteric Nervous System Affects Inflammation in Experimental Colitis and Crohn's Disease.
Journal of Crohn's & colitis11(9)1113-1123(2017 Sep)
Feldbr?gge L,Moss AC,Yee EU,Csizmadia E,Mitsuhashi S,Longhi MS,Sandhu B,Stephan H,Wu Y,Cheifetz AS,M?ller CE,S?vigny J,Robson SC,Jiang ZG

Increased expression of NTPDases 2 and 3 in mesenteric endothelial cells during schistosomiasis favors leukocyte adhesion through P2Y1 receptors.
Vascular pharmacology8266-72(2016 Jul)
Oliveira SD,Oliveira NF,Meyer-Fernandes JR,Savio LE,Ornelas FG,Ferreira ZS,Coutinho-Silva R,Silva CL

Neuronal NTPDase3 Mediates Extracellular ATP Degradation in Trigeminal Nociceptive Pathway.
PloS one11(10)e0164028(2016)
Ma L,Trinh T,Ren Y,Dirksen RT,Liu X

NTPDase3 and ecto-5'-nucleotidase/CD73 are differentially expressed during mouse bladder cancer progression.
Purinergic signalling10(3)421-30(2014 Sep)
Rockenbach L,Braganhol E,Dietrich F,Figueir? F,Pugliese M,Edelweiss MI,Morrone FB,S?vigny J,Battastini AM

Deletion of ENTPD3 does not impair nucleotide hydrolysis in primary somatosensory neurons or spinal cord.
F1000Research3163(2014)
McCoy E,Street S,Taylor-Blake B,Yi J,Edwards M,Wightman M,Zylka M

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Entpd3 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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