Tap1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tap1
Entrez Gene ID	21354
Full Name	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
Synonyms	ABC17,APT1,Abcb2,Ham-1,Ham1,MTP1,PSF1,RING4,TAP,Tap-1,Y3
General protein information	Preferred Names transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) Names antigen peptide transporter 1 ABC transporter, MHC, 1 ATP dependent transport protein family member ATP-binding cassette sub-family B member 2 ATP-binding cassette transporter, major histocompatibility complex, 1 ATP-binding cassette, sub-family B (MDR/TAP), member 2 histocompatibility antigen modifier 1 peptide supply factor 1 peptide transporter PSF1 peptide transporter TAP1 transporter 1 ATP-binding cassette sub-family B transporter 1, ABC (ATP binding cassette) transporter associated with antigen processing 1 transporter, ABC, MHC, 1 transporter, ATP-binding cassette, major histocompatibility complex, 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17 B1\|17 17.98 cM
Summary	The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This protein forms a heterodimer with Tap2 that transports short peptides from the cytosol into the endoplasmic reticulum lumen. Mutations in the human gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001161730.1	NP_001155202.1	antigen peptide transporter 1 isoform 2
NM_013683.2	NP_038711.2	antigen peptide transporter 1 isoform 1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Tap1	NP_038711.2
Rattus norvegicus (Norway rat)	Tap1	NP_114444.2
Xenopus tropicalis (tropical clawed frog)	LOC100488534	XP_002942646.1
Danio rerio (zebrafish)	tap1	XP_002665053.1
Canis lupus familiaris (dog)	TAP1	XP_005627251.1
Gallus gallus (chicken)	TAP1	NP_001129440.1
Homo sapiens (human)	TAP1	NP_000584.2
Pan troglodytes (chimpanzee)	TAP1	XP_001166911.2
	TAP1	XP_001115506.1
Bos taurus (cattle)	TAP1	NP_001091527.1

Gene Ontology
Bibliography

Related articles in PubMed

Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair.
Linehan JL, Harrison OJ, Han SJ, Byrd AL, Vujkovic-Cvijin I, Villarino AV, Sen SK, Shaik J, Smelkinson M, Tamoutounour S, Collins N, Bouladoux N, Dzutsev A, Rosshart SP, Arbuckle JH, Wang CR, Kristie TM, Rehermann B, Trinchieri G, Brenchley JM, O'Shea JJ, Belkaid Y
Cell(2018 Jan)

Conventional CD4
Cruz-Adalia A, Ramirez-Santiago G, Osuna-P?rez J, Torres-Torresano M, Zorita V, Mart?nez-Ria?o A, Boccasavia V, Borroto A, Mart?nez Del Hoyo G, Goz?lez-Granado JM, Alarc?n B, S?nchez-Madrid F, Veiga E
Nature communications8(1)1591(2017 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TAP-independent self-peptides enhance T cell recognition of immune-escaped tumors.
Title: TAP-independent self-peptides enhance T cell recognition of immune-escaped tumors.

Knocking out Tap1 abolishes NMDAR-dependent LTD in area CA1 of adult mouse hippocampus and is accompanied by memory deficits. MHC class I expression could be an unexpected cause of disrupted synaptic plasticity and cognitive deficits.
Title: MHC class I immune proteins are critical for hippocampus-dependent memory and gate NMDAR-dependent hippocampal long-term depression.

It transport class I antigens to cell surface of CD8 positive lymphocytes which have a vital role in liver inflammation like fructose-induced steatosis.
Title: Antigen peptide transporter 1 is involved in the development of fructose-induced hepatic steatosis in mice.

Role of metalloproteases in vaccinia virus epitope processing for transporter associated with antigen processing (TAP)-independent human leukocyte antigen (HLA)-B7 class I antigen presentation.
Title: Role of metalloproteases in vaccinia virus epitope processing for transporter associated with antigen processing (TAP)-independent human leukocyte antigen (HLA)-B7 class I antigen presentation.

Apoe(-/-)Tap1(-/-) mice develop atherosclerosis equal to Apoe(-/-) mice, indicating a minor role for CD8(+) T cells and TAP1-dependent antigen presentation in the disease process.
Title: TAP1-deficiency does not alter atherosclerosis development in Apoe-/- mice.

The following Tap1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tap1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu23745	NM_001161730.1 Latest version!	Mus musculus transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) (Tap1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OMu23749	NM_013683.2 Latest version!	Mus musculus transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) (Tap1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tap1 ( NM_001161730.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001155202.1 Mus musculus transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) (Tap1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu23745
Clone ID Related Accession (Same CDS sequence)	NM_001161730.1
Accession Version	NM_001161730.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2091bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-30
Organism	Mus musculus(house mouse)
Product	antigen peptide transporter 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK167485.1, AK171363.1 and AK152953.1. Transcript Variant: This variant (2) lacks an alternate in-frame segment compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK171363.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849379 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGCGC ACGTCTGGCT GGCGGCCGCC CTGCTCCTTC TGGTGGACTG GCTGCTGCTG 
CGGCCCATGC TCCCGGGAAT CTTCTCCCTG TTGGTTCCCG AGGTGCCGCT GCTCCGGGTC 
TGGGTGGTGG GCCTGAGTCG CTGGGCCATC CTAGGACTAG GGGTCCGCGG GGTCCTCGGG 
GTCACCGCAG GAGCCCATGG CTGGCTGGCT GCTTTGCAGC CGCTGGTGGC CGCACTGAGT 
TTGGCCCTGC CTGGACTTGC CTTGTTCCGA GAGCTGGCCG CCTGGGGAAC ACTCCGGGAG 
GGTGACAGCG CTGGATTACT GTACTGGAAC AGTCGTCCAG ATGCCTTCGC TATCAGTTAT 
GTGGCAGCAT TGCCCGCAGC CGCCCTGTGG CACAAGTTGG GGAGCCTCTG GGCGCCCAGC 
GGCAACAGGG ACGCTGGAGA CATGCTGTGT CGGATGCTGG GCTTCCTGGG CCCTAAGAAG 
AGACGTCTCT ACCTGGTTCT GGTTCTCTTG ATTCTCTCTT GCCTTGGGGA AATGGCCATT 
CCCTTCTTCA CGGGCCGCAT CACTGACTGG ATTCTTCAGG ATAAGACAGT TCCTAGCTTC 
ACCCGCAACA TATGGCTCAT GTCCATTCTC ACCATAGCCA GCACAGCGCT GGAGTTTGCA 
AGTGATGGAA TCTACAACAT CACCATGGGA CACATGCACG GCCGTGTGCA CAGAGAGGTG 
TTTCGGGCCG TCCTTCGCCA GGAGACAGGG TTTTTCCTGA AGAACCCAGC AGGTTCCATC 
ACATCTCGGG TGACTGAGGA CACAGCCAAC GTGTGCGAGT CCATTAGTGG CACGCTGAGC 
CTGCTGCTGT GGTACCTGGG GCGAGCCCTG TGTCTCTTGG TGTTCATGTT TTGGGGGTCA 
CCGTACCTCA CTCTGGTCAC CCTGATCAAC CTGCCCCTGC TTTTTCTTTT GCCTAAGAAG 
CTGGGAAAAG TGCATCAGTC ACTGGCAGTG AAGGTGCAGG AGTCTCTAGC AAAGTCCACG 
CAGGTGGCCC TTGAGGCCTT ATCGGCGATG CCTACTGTGC GGAGCTTTGC CAACGAGGAG 
GGTGAGGCCC AGAAGTTCAG GCAGAAGTTG GAAGAAATGA AGACTCTAAA CAAGAAGGAG 
GCCTTGGCTT ACGTGGCTGA AGTCTGGACC ACGAGTGTCT CGGGAATGCT GCTGAAGCTT 
CAGTTCACCC AGGCTGTTCA GGTCCTGCTC TCCCTCTACC CCTCCATGCA GAAGGCTGTG 
GGCTCCTCAG AGAAAATATT CGAATACTTG GACCGGACTC CTTGCTCTCC ACTCAGTGGC 
TCGTTGGCAC CCTCAAACAT GAAAGGCCTT GTGGAGTTCC AAGATGTCTC TTTTGCCTAC 
CCAAACCAGC CCAAAGTCCA GGTGCTTCAG GGGCTGACGT TCACCCTGCA TCCTGGAACG 
GTGACAGCGT TGGTGGGACC CAATGGATCA GGGAAGAGCA CCGTGGCTGC CCTGCTGCAG 
AACCTGTACC AGCCCACCGG GGGCCAGCTG CTGCTGGATG GCCAGTGCCT GGTCCAGTAT 
GATCACCATT ACCTGCACAC TCAGGTGGCC GCAGTGGGAC AAGAGCCGCT GCTATTTGGA 
AGAAGCTTTC GAGAAAATAT TGCGTATGGC CTGAACCGGA CTCCAACCAT GGAGGAAATC 
ACAGCTGTGG CCGTGGAGTC TGGAGCCCAC GATTTCATCT CTGGGTTCCC TCAGGGCTAT 
GACACAGAGG TAGGTGAGAC TGGGAACCAG CTGTCAGGAG GTCAGCGACA GGCAGTGGCC 
TTGGCCCGAG CCTTGATCCG GAAGCCACTC CTGCTTATCT TGGATGATGC CACCAGTGCC 
CTGGATGCTG GCAACCAGCT ACGGGTCCAG CGGCTCCTGT ATGAGAGCCC CAAGCGGGCT 
TCTCGGACGG TTCTTCTTAT CACCCAGCAG CTCAGCCTGG CAGAGCAGGC CCACCACATC 
CTCTTTCTCA GAGAAGGCTC TGTCGGCGAG CAGGGCACCC ACCTGCAGCT CATGAAGAGA 
GGAGGGTGCT ACCGGGCCAT GGTAGAGGCT CTTGCGGCTC CTGCAGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001155202.1
CDS	325..2415
Translation	MAAHVWLAAALLLLVDWLLLRPMLPGIFSLLVPEVPLLRVWVVGLSRWAILGLGVRGVLGVTAGAHGWLAALQPLVAALSLALPGLALFRELAAWGTLREGDSAGLLYWNSRPDAFAISYVAALPAAALWHKLGSLWAPSGNRDAGDMLCRMLGFLGPKKRRLYLVLVLLILSCLGEMAIPFFTGRITDWILQDKTVPSFTRNIWLMSILTIASTALEFASDGIYNITMGHMHGRVHREVFRAVLRQETGFFLKNPAGSITSRVTEDTANVCESISGTLSLLLWYLGRALCLLVFMFWGSPYLTLVTLINLPLLFLLPKKLGKVHQSLAVKVQESLAKSTQVALEALSAMPTVRSFANEEGEAQKFRQKLEEMKTLNKKEALAYVAEVWTTSVSGMLLKLQFTQAVQVLLSLYPSMQKAVGSSEKIFEYLDRTPCSPLSGSLAPSNMKGLVEFQDVSFAYPNQPKVQVLQGLTFTLHPGTVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGQCLVQYDHHYLHTQVAAVGQEPLLFGRSFRENIAYGLNRTPTMEEITAVAVESGAHDFISGFPQGYDTEVGETGNQLSGGQRQAVALARALIRKPLLLILDDATSALDAGNQLRVQRLLYESPKRASRTVLLITQQLSLAEQAHHILFLREGSVGEQGTHLQLMKRGGCYRAMVEALAAPAD

Target ORF information:

RefSeq Version	NM_001161730.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) (Tap1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001161730.1

ORF Insert Sequence:

ATGGCTGCGC ACGTCTGGCT GGCGGCCGCC CTGCTCCTTC TGGTGGACTG GCTGCTGCTG 
CGGCCCATGC TCCCGGGAAT CTTCTCCCTG TTGGTTCCCG AGGTGCCGCT GCTCCGGGTC 
TGGGTGGTGG GCCTGAGTCG CTGGGCCATC CTAGGACTAG GGGTCCGCGG GGTCCTCGGG 
GTCACCGCAG GAGCCCATGG CTGGCTGGCT GCTTTGCAGC CGCTGGTGGC CGCACTGAGT 
TTGGCCCTGC CTGGACTTGC CTTGTTCCGA GAGCTGGCCG CCTGGGGAAC ACTCCGGGAG 
GGTGACAGCG CTGGATTACT GTACTGGAAC AGTCGTCCAG ATGCCTTCGC TATCAGTTAT 
GTGGCAGCAT TGCCCGCAGC CGCCCTGTGG CACAAGTTGG GGAGCCTCTG GGCGCCCAGC 
GGCAACAGGG ACGCTGGAGA CATGCTGTGT CGGATGCTGG GCTTCCTGGG CCCTAAGAAG 
AGACGTCTCT ACCTGGTTCT GGTTCTCTTG ATTCTCTCTT GCCTTGGGGA AATGGCCATT 
CCCTTCTTCA CGGGCCGCAT CACTGACTGG ATTCTTCAGG ATAAGACAGT TCCTAGCTTC 
ACCCGCAACA TATGGCTCAT GTCCATTCTC ACCATAGCCA GCACAGCGCT GGAGTTTGCA 
AGTGATGGAA TCTACAACAT CACCATGGGA CACATGCACG GCCGTGTGCA CAGAGAGGTG 
TTTCGGGCCG TCCTTCGCCA GGAGACAGGG TTTTTCCTGA AGAACCCAGC AGGTTCCATC 
ACATCTCGGG TGACTGAGGA CACAGCCAAC GTGTGCGAGT CCATTAGTGG CACGCTGAGC 
CTGCTGCTGT GGTACCTGGG GCGAGCCCTG TGTCTCTTGG TGTTCATGTT TTGGGGGTCA 
CCGTACCTCA CTCTGGTCAC CCTGATCAAC CTGCCCCTGC TTTTTCTTTT GCCTAAGAAG 
CTGGGAAAAG TGCATCAGTC ACTGGCAGTG AAGGTGCAGG AGTCTCTAGC AAAGTCCACG 
CAGGTGGCCC TTGAGGCCTT ATCGGCGATG CCTACTGTGC GGAGCTTTGC CAACGAGGAG 
GGTGAGGCCC AGAAGTTCAG GCAGAAGTTG GAAGAAATGA AGACTCTAAA CAAGAAGGAG 
GCCTTGGCTT ACGTGGCTGA AGTCTGGACC ACGAGTGTCT CGGGAATGCT GCTGAAGCTT 
CAGTTCACCC AGGCTGTTCA GGTCCTGCTC TCCCTCTACC CCTCCATGCA GAAGGCTGTG 
GGCTCCTCAG AGAAAATATT CGAATACTTG GACCGGACTC CTTGCTCTCC ACTCAGTGGC 
TCGTTGGCAC CCTCAAACAT GAAAGGCCTT GTGGAGTTCC AAGATGTCTC TTTTGCCTAC 
CCAAACCAGC CCAAAGTCCA GGTGCTTCAG GGGCTGACGT TCACCCTGCA TCCTGGAACG 
GTGACAGCGT TGGTGGGACC CAATGGATCA GGGAAGAGCA CCGTGGCTGC CCTGCTGCAG 
AACCTGTACC AGCCCACCGG GGGCCAGCTG CTGCTGGATG GCCAGTGCCT GGTCCAGTAT 
GATCACCATT ACCTGCACAC TCAGGTGGCC GCAGTGGGAC AAGAGCCGCT GCTATTTGGA 
AGAAGCTTTC GAGAAAATAT TGCGTATGGC CTGAACCGGA CTCCAACCAT GGAGGAAATC 
ACAGCTGTGG CCGTGGAGTC TGGAGCCCAC GATTTCATCT CTGGGTTCCC TCAGGGCTAT 
GACACAGAGG TAGGTGAGAC TGGGAACCAG CTGTCAGGAG GTCAGCGACA GGCAGTGGCC 
TTGGCCCGAG CCTTGATCCG GAAGCCACTC CTGCTTATCT TGGATGATGC CACCAGTGCC 
CTGGATGCTG GCAACCAGCT ACGGGTCCAG CGGCTCCTGT ATGAGAGCCC CAAGCGGGCT 
TCTCGGACGG TTCTTCTTAT CACCCAGCAG CTCAGCCTGG CAGAGCAGGC CCACCACATC 
CTCTTTCTCA GAGAAGGCTC TGTCGGCGAG CAGGGCACCC ACCTGCAGCT CATGAAGAGA 
GGAGGGTGCT ACCGGGCCAT GGTAGAGGCT CTTGCGGCTC CTGCAGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tap1 ( NM_013683.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_038711.2 Mus musculus transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) (Tap1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu23749
Clone ID Related Accession (Same CDS sequence)	NM_013683.2
Accession Version	NM_013683.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2175bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-30
Organism	Mus musculus(house mouse)
Product	antigen peptide transporter 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK167485.1, AK162731.1 and AK152953.1. On Jun 12, 2009 this sequence version replaced NM_013683.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK166046.1, AK167485.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGCGC ACGTCTGGCT GGCGGCCGCC CTGCTCCTTC TGGTGGACTG GCTGCTGCTG 
CGGCCCATGC TCCCGGGAAT CTTCTCCCTG TTGGTTCCCG AGGTGCCGCT GCTCCGGGTC 
TGGGTGGTGG GCCTGAGTCG CTGGGCCATC CTAGGACTAG GGGTCCGCGG GGTCCTCGGG 
GTCACCGCAG GAGCCCATGG CTGGCTGGCT GCTTTGCAGC CGCTGGTGGC CGCACTGAGT 
TTGGCCCTGC CTGGACTTGC CTTGTTCCGA GAGCTGGCCG CCTGGGGAAC ACTCCGGGAG 
GGTGACAGCG CTGGATTACT GTACTGGAAC AGTCGTCCAG ATGCCTTCGC TATCAGTTAT 
GTGGCAGCAT TGCCCGCAGC CGCCCTGTGG CACAAGTTGG GGAGCCTCTG GGCGCCCAGC 
GGCAACAGGG ACGCTGGAGA CATGCTGTGT CGGATGCTGG GCTTCCTGGG CCCTAAGAAG 
AGACGTCTCT ACCTGGTTCT GGTTCTCTTG ATTCTCTCTT GCCTTGGGGA AATGGCCATT 
CCCTTCTTCA CGGGCCGCAT CACTGACTGG ATTCTTCAGG ATAAGACAGT TCCTAGCTTC 
ACCCGCAACA TATGGCTCAT GTCCATTCTC ACCATAGCCA GCACAGCGCT GGAGTTTGCA 
AGTGATGGAA TCTACAACAT CACCATGGGA CACATGCACG GCCGTGTGCA CAGAGAGGTG 
TTTCGGGCCG TCCTTCGCCA GGAGACAGGG TTTTTCCTGA AGAACCCAGC AGGTTCCATC 
ACATCTCGGG TGACTGAGGA CACAGCCAAC GTGTGCGAGT CCATTAGTGG CACGCTGAGC 
CTGCTGCTGT GGTACCTGGG GCGAGCCCTG TGTCTCTTGG TGTTCATGTT TTGGGGGTCA 
CCGTACCTCA CTCTGGTCAC CCTGATCAAC CTGCCCCTGC TTTTTCTTTT GCCTAAGAAG 
CTGGGAAAAG TGCATCAGTC ACTGGCAGTG AAGGTGCAGG AGTCTCTAGC AAAGTCCACG 
CAGGTGGCCC TTGAGGCCTT ATCGGCGATG CCTACTGTGC GGAGCTTTGC CAACGAGGAG 
GGTGAGGCCC AGAAGTTCAG GCAGAAGTTG GAAGAAATGA AGACTCTAAA CAAGAAGGAG 
GCCTTGGCTT ACGTGGCTGA AGTCTGGACC ACGAGTGTCT CGGGAATGCT GCTGAAGGTG 
GGAATTCTGT ACCTGGGCGG GCAGCTGGTG ATCAGAGGGG CTGTCAGCAG CGGCAACCTT 
GTCTCATTCG TTCTCTACCA GCTTCAGTTC ACCCAGGCTG TTCAGGTCCT GCTCTCCCTC 
TACCCCTCCA TGCAGAAGGC TGTGGGCTCC TCAGAGAAAA TATTCGAATA CTTGGACCGG 
ACTCCTTGCT CTCCACTCAG TGGCTCGTTG GCACCCTCAA ACATGAAAGG CCTTGTGGAG 
TTCCAAGATG TCTCTTTTGC CTACCCAAAC CAGCCCAAAG TCCAGGTGCT TCAGGGGCTG 
ACGTTCACCC TGCATCCTGG AACGGTGACA GCGTTGGTGG GACCCAATGG ATCAGGGAAG 
AGCACCGTGG CTGCCCTGCT GCAGAACCTG TACCAGCCCA CCGGGGGCCA GCTGCTGCTG 
GATGGCCAGT GCCTGGTCCA GTATGATCAC CATTACCTGC ACACTCAGGT GGCCGCAGTG 
GGACAAGAGC CGCTGCTATT TGGAAGAAGC TTTCGAGAAA ATATTGCGTA TGGCCTGAAC 
CGGACTCCAA CCATGGAGGA AATCACAGCT GTGGCCGTGG AGTCTGGAGC CCACGATTTC 
ATCTCTGGGT TCCCTCAGGG CTATGACACA GAGGTAGGTG AGACTGGGAA CCAGCTGTCA 
GGAGGTCAGC GACAGGCAGT GGCCTTGGCC CGAGCCTTGA TCCGGAAGCC ACTCCTGCTT 
ATCTTGGATG ATGCCACCAG TGCCCTGGAT GCTGGCAACC AGCTACGGGT CCAGCGGCTC 
CTGTATGAGA GCCCCAAGCG GGCTTCTCGG ACGGTTCTTC TTATCACCCA GCAGCTCAGC 
CTGGCAGAGC AGGCCCACCA CATCCTCTTT CTCAGAGAAG GCTCTGTCGG CGAGCAGGGC 
ACCCACCTGC AGCTCATGAA GAGAGGAGGG TGCTACCGGG CCATGGTAGA GGCTCTTGCG 
GCTCCTGCAG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038711.2
CDS	325..2499
Translation	MAAHVWLAAALLLLVDWLLLRPMLPGIFSLLVPEVPLLRVWVVGLSRWAILGLGVRGVLGVTAGAHGWLAALQPLVAALSLALPGLALFRELAAWGTLREGDSAGLLYWNSRPDAFAISYVAALPAAALWHKLGSLWAPSGNRDAGDMLCRMLGFLGPKKRRLYLVLVLLILSCLGEMAIPFFTGRITDWILQDKTVPSFTRNIWLMSILTIASTALEFASDGIYNITMGHMHGRVHREVFRAVLRQETGFFLKNPAGSITSRVTEDTANVCESISGTLSLLLWYLGRALCLLVFMFWGSPYLTLVTLINLPLLFLLPKKLGKVHQSLAVKVQESLAKSTQVALEALSAMPTVRSFANEEGEAQKFRQKLEEMKTLNKKEALAYVAEVWTTSVSGMLLKVGILYLGGQLVIRGAVSSGNLVSFVLYQLQFTQAVQVLLSLYPSMQKAVGSSEKIFEYLDRTPCSPLSGSLAPSNMKGLVEFQDVSFAYPNQPKVQVLQGLTFTLHPGTVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGQCLVQYDHHYLHTQVAAVGQEPLLFGRSFRENIAYGLNRTPTMEEITAVAVESGAHDFISGFPQGYDTEVGETGNQLSGGQRQAVALARALIRKPLLLILDDATSALDAGNQLRVQRLLYESPKRASRTVLLITQQLSLAEQAHHILFLREGSVGEQGTHLQLMKRGGCYRAMVEALAAPAD

Target ORF information:

RefSeq Version	NM_013683.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) (Tap1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013683.2

ORF Insert Sequence:

ATGGCTGCGC ACGTCTGGCT GGCGGCCGCC CTGCTCCTTC TGGTGGACTG GCTGCTGCTG 
CGGCCCATGC TCCCGGGAAT CTTCTCCCTG TTGGTTCCCG AGGTGCCGCT GCTCCGGGTC 
TGGGTGGTGG GCCTGAGTCG CTGGGCCATC CTAGGACTAG GGGTCCGCGG GGTCCTCGGG 
GTCACCGCAG GAGCCCATGG CTGGCTGGCT GCTTTGCAGC CGCTGGTGGC CGCACTGAGT 
TTGGCCCTGC CTGGACTTGC CTTGTTCCGA GAGCTGGCCG CCTGGGGAAC ACTCCGGGAG 
GGTGACAGCG CTGGATTACT GTACTGGAAC AGTCGTCCAG ATGCCTTCGC TATCAGTTAT 
GTGGCAGCAT TGCCCGCAGC CGCCCTGTGG CACAAGTTGG GGAGCCTCTG GGCGCCCAGC 
GGCAACAGGG ACGCTGGAGA CATGCTGTGT CGGATGCTGG GCTTCCTGGG CCCTAAGAAG 
AGACGTCTCT ACCTGGTTCT GGTTCTCTTG ATTCTCTCTT GCCTTGGGGA AATGGCCATT 
CCCTTCTTCA CGGGCCGCAT CACTGACTGG ATTCTTCAGG ATAAGACAGT TCCTAGCTTC 
ACCCGCAACA TATGGCTCAT GTCCATTCTC ACCATAGCCA GCACAGCGCT GGAGTTTGCA 
AGTGATGGAA TCTACAACAT CACCATGGGA CACATGCACG GCCGTGTGCA CAGAGAGGTG 
TTTCGGGCCG TCCTTCGCCA GGAGACAGGG TTTTTCCTGA AGAACCCAGC AGGTTCCATC 
ACATCTCGGG TGACTGAGGA CACAGCCAAC GTGTGCGAGT CCATTAGTGG CACGCTGAGC 
CTGCTGCTGT GGTACCTGGG GCGAGCCCTG TGTCTCTTGG TGTTCATGTT TTGGGGGTCA 
CCGTACCTCA CTCTGGTCAC CCTGATCAAC CTGCCCCTGC TTTTTCTTTT GCCTAAGAAG 
CTGGGAAAAG TGCATCAGTC ACTGGCAGTG AAGGTGCAGG AGTCTCTAGC AAAGTCCACG 
CAGGTGGCCC TTGAGGCCTT ATCGGCGATG CCTACTGTGC GGAGCTTTGC CAACGAGGAG 
GGTGAGGCCC AGAAGTTCAG GCAGAAGTTG GAAGAAATGA AGACTCTAAA CAAGAAGGAG 
GCCTTGGCTT ACGTGGCTGA AGTCTGGACC ACGAGTGTCT CGGGAATGCT GCTGAAGGTG 
GGAATTCTGT ACCTGGGCGG GCAGCTGGTG ATCAGAGGGG CTGTCAGCAG CGGCAACCTT 
GTCTCATTCG TTCTCTACCA GCTTCAGTTC ACCCAGGCTG TTCAGGTCCT GCTCTCCCTC 
TACCCCTCCA TGCAGAAGGC TGTGGGCTCC TCAGAGAAAA TATTCGAATA CTTGGACCGG 
ACTCCTTGCT CTCCACTCAG TGGCTCGTTG GCACCCTCAA ACATGAAAGG CCTTGTGGAG 
TTCCAAGATG TCTCTTTTGC CTACCCAAAC CAGCCCAAAG TCCAGGTGCT TCAGGGGCTG 
ACGTTCACCC TGCATCCTGG AACGGTGACA GCGTTGGTGG GACCCAATGG ATCAGGGAAG 
AGCACCGTGG CTGCCCTGCT GCAGAACCTG TACCAGCCCA CCGGGGGCCA GCTGCTGCTG 
GATGGCCAGT GCCTGGTCCA GTATGATCAC CATTACCTGC ACACTCAGGT GGCCGCAGTG 
GGACAAGAGC CGCTGCTATT TGGAAGAAGC TTTCGAGAAA ATATTGCGTA TGGCCTGAAC 
CGGACTCCAA CCATGGAGGA AATCACAGCT GTGGCCGTGG AGTCTGGAGC CCACGATTTC 
ATCTCTGGGT TCCCTCAGGG CTATGACACA GAGGTAGGTG AGACTGGGAA CCAGCTGTCA 
GGAGGTCAGC GACAGGCAGT GGCCTTGGCC CGAGCCTTGA TCCGGAAGCC ACTCCTGCTT 
ATCTTGGATG ATGCCACCAG TGCCCTGGAT GCTGGCAACC AGCTACGGGT CCAGCGGCTC 
CTGTATGAGA GCCCCAAGCG GGCTTCTCGG ACGGTTCTTC TTATCACCCA GCAGCTCAGC 
CTGGCAGAGC AGGCCCACCA CATCCTCTTT CTCAGAGAAG GCTCTGTCGG CGAGCAGGGC 
ACCCACCTGC AGCTCATGAA GAGAGGAGGG TGCTACCGGG CCATGGTAGA GGCTCTTGCG 
GCTCCTGCAG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair.
Cell(2018 Jan)
Linehan JL,Harrison OJ,Han SJ,Byrd AL,Vujkovic-Cvijin I,Villarino AV,Sen SK,Shaik J,Smelkinson M,Tamoutounour S,Collins N,Bouladoux N,Dzutsev A,Rosshart SP,Arbuckle JH,Wang CR,Kristie TM,Rehermann B,Trinchieri G,Brenchley JM,O'Shea JJ,Belkaid Y

Conventional CD4
Nature communications8(1)1591(2017 Nov)
Cruz-Adalia A,Ramirez-Santiago G,Osuna-P?rez J,Torres-Torresano M,Zorita V,Mart?nez-Ria?o A,Boccasavia V,Borroto A,Mart?nez Del Hoyo G,Goz?lez-Granado JM,Alarc?n B,S?nchez-Madrid F,Veiga E

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Tap1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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