Trp53bp2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Trp53bp2
Entrez Gene ID	209456
Full Name	transformation related protein 53 binding protein 2
Synonyms	53BP2,AI746547,ASPP2,PPP1R13A,Tp53bp2,X98550
General protein information	Preferred Names transformation related protein 53 binding protein 2 Names apoptosis-stimulating of p53 protein 2 p53-binding protein 2 p53BP2 tumor protein p53 binding protein, 2 tumor suppressor p53-binding protein 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1 H5\|1 84.93 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_173378.2	NP_775554.2	apoptosis-stimulating of p53 protein 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TP53BP2	XP_003308815.1
	TP53BP2	XP_001093747.2
Homo sapiens (human)	TP53BP2	NP_001026855.2
Canis lupus familiaris (dog)	TP53BP2	XP_547518.3
Xenopus tropicalis (tropical clawed frog)	tp53bp2	NP_001016036.2
Bos taurus (cattle)	TP53BP2	XP_002694012.2
Danio rerio (zebrafish)	tp53bp2	NP_999979.1
Mus musculus (house mouse)	Trp53bp2	NP_775554.2
Rattus norvegicus (Norway rat)	Tp53bp2	XP_223012.6
Gallus gallus (chicken)	TP53BP2	XP_419394.4

Gene Ontology
Bibliography

Related articles in PubMed

?N-ASPP2, a novel isoform of the ASPP2 tumor suppressor, promotes cellular survival.
Van Hook K, Wang Z, Chen D, Nold C, Zhu Z, Anur P, Lee HJ, Yu Z, Sheppard B, Dai MS, Sears R, Spellman P, Lopez CD
Biochemical and biophysical research communications482(4)1271-1277(2017 Jan)

ASPP2 deficiency causes features of 1q41q42 microdeletion syndrome.
Zak J, Vives V, Szumska D, Vernet A, Schneider JE, Miller P, Slee EA, Joss S, Lacassie Y, Chen E, Escobar LF, Tucker M, Aylsworth AS, Dubbs HA, Collins AT, Andrieux J, Dieux-Coeslier A, Haberlandt E, Kotzot D, Scott DA, Parker MJ, Zakaria Z, Choy YS, Wieczorek D, Innes AM, Jun KR, Zinner S, Prin F, Lygate CA, Pretorius P, Rosenfeld JA, Mohun TJ, Lu X
Cell death and differentiation23(12)1973-1984(2016 Dec)

ASPP2 involvement in p53-mediated HIV-1 envelope glycoprotein gp120 neurotoxicity in mice cerebrocortical neurons.
Liu Z, Zang Y, Qiao L, Liu K, Ouyang Y, Zhang Y, Chen D
Scientific reports633378(2016 Sep)

ASPP2 Is a Novel Pan-Ras Nanocluster Scaffold.
Posada IM, Serulla M, Zhou Y, Oetken-Lindholm C, Abankwa D, Lectez B
PloS one11(7)e0159677(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These findings identify TP53BP2 as a strong candidate causative gene for central nervous system (CNS) defects in 1q41q42 microdeletion syndrome.
Title: ASPP2 deficiency causes features of 1q41q42 microdeletion syndrome.

SPP2 dominates the biological outcome, thus switching from a Gal-1 supported growth-promoting setting to a senescence inducing and stemness suppressive program in cancer cells. Our results support Ras nanocluster as major integrators of tumour fate decision events.
Title: ASPP2 Is a Novel Pan-Ras Nanocluster Scaffold.

ASPP2 may participate in the lipid metabolism of non-alcoholic steatohepatitis and attenuate liver failure.
Title: ASPP2 attenuates triglycerides to protect against hepatocyte injury by reducing autophagy in a cell and mouse model of non-alcoholic fatty liver disease.

ASPP2 prevents beta-catenin from transactivating ZEB1 directly by forming an ASPP2-beta-catenin-E-cadherin ternary complex
Title: ASPP2 controls epithelial plasticity and inhibits metastasis through ?-catenin-dependent regulation of ZEB1.

findings suggest that the identified STAT1/ASPP2 pathway may connect tumor suppression and cell polarity to neuroinflammation
Title: STAT1-induced ASPP2 transcription identifies a link between neuroinflammation, cell polarity, and tumor suppression.

The following Trp53bp2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Trp53bp2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu04519	NM_173378.2 Latest version!	Mus musculus transformation related protein 53 binding protein 2 (Trp53bp2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$664.30 $949.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Trp53bp2 ( NM_173378.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_775554.2 Mus musculus transformation related protein 53 binding protein 2 (Trp53bp2), mRNA.

Price & Availability↑

CloneID	OMu04519
Clone ID Related Accession (Same CDS sequence)	NM_173378.2
Accession Version	NM_173378.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3405bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Mus musculus(house mouse)
Product	apoptosis-stimulating of p53 protein 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY020445.1, BQ180182.1, CN529251.1, AK134556.1, AC131742.2 and AW990556.1. On Aug 18, 2006 this sequence version replaced NM_173378.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCGGTTCG GGTCCAAAAT GATGCCGATG TTCCTGACAG TTTACCTCAG TAACAGTGAG 
CAGCACTTCA CAGAAGTTCC TGTTACCCCA GAGACAATAT GCAGAGATGT GGTGGATCTG 
TGCAAGGAGC CTGGAGAGAA CGACTGCCAT TTAGCCGAAG TGTGGTGTGG CTCTGAACGC 
CCAGTTGCTG ATAACGAACG GATGTTTGAT GTTCTTCAGC GGTTTGGAAG TCAAAGGAAT 
GAAGTTCGCT TCTTTCTTCG TCATGAACGC CCCCCTAACA GGGACATTGT GAGTGGACCG 
AGATCCCAAG ATCCAAGTGT AAAAAGAAAT GGTGTCAAAG TTCCCGGCGA GCATCGGAGG 
AAGGAGAATG GGGTTAACAG TCCTAGGCTG GACCTGACGC TTGCTGAGCT CCAGGAGATG 
GCATCTCGCC AGCAGCAGCA GATCGAGGCC CAGCAACAAA TGCTGGCTAC TAAGGAGCAA 
CGCTTAAAGT TTTTAAAACA GCAAGATCAA CGTCAACAGC AACAAGCTGC TGAACAGGAG 
AAACTTAAGA GGCTTAGAGA AATAGCTGAA AGTCAGGAAG CTAAGCTTAA GAAAGTGAGA 
GCGCTAAAGG GCCATGTGGA GCAAAAGAGG CTGAGCAACG GAAAACTCGT GGAGGAGATC 
GAGCAGATGA ATAGCTTGTT CCAGCAGAAG CAGAGGGAGC TGGTGCTGGC TGTGTCGAAA 
GTGGAGGAGC TGACGAGGCA GCTGGAGATG CTGAAGAACG GCAGGATCGA TGGCCACCAC 
GACAACCAGT CGGCCGTGGC TGAGCTGGAC CGCCTTTACA AGGAGCTGCA GTTAAGAAAC 
AAACTGAACC AAGAGCAGAA TGCCAAGCTG CAACAACAGA GGGAGTGTTT GAATAAGCGC 
AATTCAGAGG TGGCCGTCAT GGATAAACGC GTCAGTGAGC TGAGGGACCG GCTGTGGAAG 
AAGAAGGCAG CACTGCAGCA GAAAGAGAAT CTCCCGGTTT CACCTGATGG AAATCTTCCC 
CAACAAGCAG TGTCAGCCCC AAGTCGTGTG GCTGCTGTAG GCCCTTACAT CCAGTCATCC 
ACTATGCCAC GGATGCCCTC CAGACCTGAG CTGCTCGTGA AGCCAGCCCT GCCTGATGGT 
TCCTTGCTCA TGCAGTCAGC AGAGGGGCCA ATGAAGATAC AGACACTGCC CAATATGAGG 
TCTGGGGCTG CTTCACAAAG TAAAGGCTCT AAAGCTCACC CAGCTAGCCC CGATTGGAAC 
CCTTCCAATG CCGACCTCTT ACCCAGCCAA GGCTCTTCTG TACCCCAGAG TGCTGGAACT 
GCTCTGGACC AAGTTGACGA TGGGGAGATT GCTGTGAGGG AGAAAGAGAA GAAAGTGCGT 
CCCTTTTCCA TGTTTGACAC AGTGGACCAG TGTGCTGCCC CACCCTCCTT TGGTACCCTG 
AGGAAAAACC AGAGCAGCGA GGACATCTTG CGGGATGCTC AGGCTGTAAA TAAAAATGTA 
GCTAAAGTAC CACCTCCCGT TCCTACAAAG CCAAAACAGA TTCATTTGCC TTACTTTGGA 
CAAACGGCTC AGTCGCCTTC TGACATGAAG CCAGATGGAA ATGCTCAGCA ATTGCCAATA 
GCTGCTACAT CCGTGGGGGC TAAGCTCAAG CCAGCAGGGC CACAGGCAAG GATGCTGCTG 
TCTCCTGGTG CCCCTTCAGG TGGTCAGGAC CAAGTCCTGT CTCCAGCATC TAAGCAAGAA 
AGTCCTCCTG CTGCTGCAGT CCGGCCCTTC ACGCCCCAGC CGTCCAAGGA CACCTTCCCT 
CCAGCCTTTC GAAAACCCCA GACTGTGGCA GCAAGCTCCA TCTATTCCAT GTACACCCAG 
CAACAGGCAC CAGGAAAAAA CTTCCAGCAG GCTGTGCAGA GTGCCTTGAC CAAGACGCAA 
CCCAGAGGCC CCCACTTTTC AAGTGTGTAT GGCAAGCCTG TGATAGCTGC TGCCCAGAAT 
CCACAACAGC ACCCAGAGAA CATTTACTCC TGTAGCCAGG GGAAGCCTGG CAGTCCGGAG 
CCCGAGACAG AGACCGTTTC TTCAGTTCAT GAGAGCCATG AAAACGAAAG GATTCCTCGA 
CCACTCAGCC CAACAAAATT ACTGCCTTTC TTGTCTAACC CTTATCGAAA CCAGAGCGAT 
GCTGACTTAG AAGCCCTGAG GAAAAAATTG TCGAATGCAC CACGGCCACT AAAGAAACGT 
AGCTCCATTA CAGAACCAGA AGGCCCTAAT GGGCCAAATA TTCAGAAACT TTTGTATCAG 
AGGACCACCA TAGCTGCCAT GGAGACCATC TCAGTCCCCT CACACCCATC TAAGTCACCA 
GGCTCAGTGA CTGTCAATCC AGAGAGCTCC GTTGAAATCC CAAATCCATA TTTACATGTG 
GAGCCAGAGA AGGAGGTGGG CTCTTTAGTC CCTGAACCAC TGTCCCCAGA GGATATGGGG 
AGTGCCAGTA CGGAGAACAG TGACGTGCCA GCTCCTTCTG CAGGCCTTGA GTATGTGTCT 
GAGGGAGTCA CAGACAGCAG TACCAATCTG CAGAATAACG TAGAAGAAAC AAACCCAGAG 
GCTCCCCACT TACTTGAAGT GTACCTAGAA GAATACCCCC CATACCCACC CCCTCCATAC 
CCATCTGGGG AGCCAGAGGT GTCCGAAGAA GACTCCGCAC GTATGCGCCC ACCTGAAATC 
ACCGGGCAGG TGTCTCTGCC TCCTGGCAAA AGGACAAACT TGCGGAAAAC TGGCTCCGAG 
CGGATTGCTC ACGGGATGAG GGTGAAATTC AACCCCCTTG CTTTGCTGCT AGATTCATCT 
CTGGAGGGAG AGTTTGATCT TGTACAGAGA ATTATCTATG AGGTTGATGA CCCAAGCCTA 
CCAAATGATG AGGGCATCAC AGCTCTTCAT AATGCTGTGT GTGCAGGCCA CACAGAAATT 
GTGAAGTTCC TGGTACAGTT CGGTGTGAAT GTAAATGCAG CAGATAGTGA TGGATGGACG 
CCATTGCATT GTGCTGCCTC CTGCAACAAT GTCCAAGTGT GTAAGTTCCT GGTGGAGTCT 
GGAGCAGCTG TGTTTGCTAT GACCTACAGT GACATGCAGA CTGCTGCAGA CAAGTGCGAG 
GAAATGGAGG AAGGCTACAC GCAGTGCTCC CAGTTTCTCT ATGGCGTTCA GGAGAAGATG 
GGCATAATGA ACAAAGGCGT CATTTATGCA CTGTGGGATT ACGAGCCGCA GCATGACGAT 
GAGCTGCTCA TGAAAGAAGG AGATTGCATG ACCGTCATCC GCAGAGAAGA TGAAGAGGAG 
ATCGAGTGGT GGTGGGCGCG CCTTAACGAT AAGGAAGGAT ATGTTCCACG CAACTTGCTA 
GGACTATACC CAAGAATTAA ACCAAGACAA AGGAGCTTGG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_775554.2
CDS	258..3662
Translation	MRFGSKMMPMFLTVYLSNSEQHFTEVPVTPETICRDVVDLCKEPGENDCHLAEVWCGSERPVADNERMFDVLQRFGSQRNEVRFFLRHERPPNRDIVSGPRSQDPSVKRNGVKVPGEHRRKENGVNSPRLDLTLAELQEMASRQQQQIEAQQQMLATKEQRLKFLKQQDQRQQQQAAEQEKLKRLREIAESQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNSLFQQKQRELVLAVSKVEELTRQLEMLKNGRIDGHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDKRVSELRDRLWKKKAALQQKENLPVSPDGNLPQQAVSAPSRVAAVGPYIQSSTMPRMPSRPELLVKPALPDGSLLMQSAEGPMKIQTLPNMRSGAASQSKGSKAHPASPDWNPSNADLLPSQGSSVPQSAGTALDQVDDGEIAVREKEKKVRPFSMFDTVDQCAAPPSFGTLRKNQSSEDILRDAQAVNKNVAKVPPPVPTKPKQIHLPYFGQTAQSPSDMKPDGNAQQLPIAATSVGAKLKPAGPQARMLLSPGAPSGGQDQVLSPASKQESPPAAAVRPFTPQPSKDTFPPAFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSALTKTQPRGPHFSSVYGKPVIAAAQNPQQHPENIYSCSQGKPGSPEPETETVSSVHESHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSHPSKSPGSVTVNPESSVEIPNPYLHVEPEKEVGSLVPEPLSPEDMGSASTENSDVPAPSAGLEYVSEGVTDSSTNLQNNVEETNPEAPHLLEVYLEEYPPYPPPPYPSGEPEVSEEDSARMRPPEITGQVSLPPGKRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQHDDELLMKEGDCMTVIRREDEEEIEWWWARLNDKEGYVPRNLLGLYPRIKPRQRSLA

Target ORF information:

RefSeq Version	NM_173378.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus transformation related protein 53 binding protein 2 (Trp53bp2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173378.2

ORF Insert Sequence:

ATGCGGTTCG GGTCCAAAAT GATGCCGATG TTCCTGACAG TTTACCTCAG TAACAGTGAG 
CAGCACTTCA CAGAAGTTCC TGTTACCCCA GAGACAATAT GCAGAGATGT GGTGGATCTG 
TGCAAGGAGC CTGGAGAGAA CGACTGCCAT TTAGCCGAAG TGTGGTGTGG CTCTGAACGC 
CCAGTTGCTG ATAACGAACG GATGTTTGAT GTTCTTCAGC GGTTTGGAAG TCAAAGGAAT 
GAAGTTCGCT TCTTTCTTCG TCATGAACGC CCCCCTAACA GGGACATTGT GAGTGGACCG 
AGATCCCAAG ATCCAAGTGT AAAAAGAAAT GGTGTCAAAG TTCCCGGCGA GCATCGGAGG 
AAGGAGAATG GGGTTAACAG TCCTAGGCTG GACCTGACGC TTGCTGAGCT CCAGGAGATG 
GCATCTCGCC AGCAGCAGCA GATCGAGGCC CAGCAACAAA TGCTGGCTAC TAAGGAGCAA 
CGCTTAAAGT TTTTAAAACA GCAAGATCAA CGTCAACAGC AACAAGCTGC TGAACAGGAG 
AAACTTAAGA GGCTTAGAGA AATAGCTGAA AGTCAGGAAG CTAAGCTTAA GAAAGTGAGA 
GCGCTAAAGG GCCATGTGGA GCAAAAGAGG CTGAGCAACG GAAAACTCGT GGAGGAGATC 
GAGCAGATGA ATAGCTTGTT CCAGCAGAAG CAGAGGGAGC TGGTGCTGGC TGTGTCGAAA 
GTGGAGGAGC TGACGAGGCA GCTGGAGATG CTGAAGAACG GCAGGATCGA TGGCCACCAC 
GACAACCAGT CGGCCGTGGC TGAGCTGGAC CGCCTTTACA AGGAGCTGCA GTTAAGAAAC 
AAACTGAACC AAGAGCAGAA TGCCAAGCTG CAACAACAGA GGGAGTGTTT GAATAAGCGC 
AATTCAGAGG TGGCCGTCAT GGATAAACGC GTCAGTGAGC TGAGGGACCG GCTGTGGAAG 
AAGAAGGCAG CACTGCAGCA GAAAGAGAAT CTCCCGGTTT CACCTGATGG AAATCTTCCC 
CAACAAGCAG TGTCAGCCCC AAGTCGTGTG GCTGCTGTAG GCCCTTACAT CCAGTCATCC 
ACTATGCCAC GGATGCCCTC CAGACCTGAG CTGCTCGTGA AGCCAGCCCT GCCTGATGGT 
TCCTTGCTCA TGCAGTCAGC AGAGGGGCCA ATGAAGATAC AGACACTGCC CAATATGAGG 
TCTGGGGCTG CTTCACAAAG TAAAGGCTCT AAAGCTCACC CAGCTAGCCC CGATTGGAAC 
CCTTCCAATG CCGACCTCTT ACCCAGCCAA GGCTCTTCTG TACCCCAGAG TGCTGGAACT 
GCTCTGGACC AAGTTGACGA TGGGGAGATT GCTGTGAGGG AGAAAGAGAA GAAAGTGCGT 
CCCTTTTCCA TGTTTGACAC AGTGGACCAG TGTGCTGCCC CACCCTCCTT TGGTACCCTG 
AGGAAAAACC AGAGCAGCGA GGACATCTTG CGGGATGCTC AGGCTGTAAA TAAAAATGTA 
GCTAAAGTAC CACCTCCCGT TCCTACAAAG CCAAAACAGA TTCATTTGCC TTACTTTGGA 
CAAACGGCTC AGTCGCCTTC TGACATGAAG CCAGATGGAA ATGCTCAGCA ATTGCCAATA 
GCTGCTACAT CCGTGGGGGC TAAGCTCAAG CCAGCAGGGC CACAGGCAAG GATGCTGCTG 
TCTCCTGGTG CCCCTTCAGG TGGTCAGGAC CAAGTCCTGT CTCCAGCATC TAAGCAAGAA 
AGTCCTCCTG CTGCTGCAGT CCGGCCCTTC ACGCCCCAGC CGTCCAAGGA CACCTTCCCT 
CCAGCCTTTC GAAAACCCCA GACTGTGGCA GCAAGCTCCA TCTATTCCAT GTACACCCAG 
CAACAGGCAC CAGGAAAAAA CTTCCAGCAG GCTGTGCAGA GTGCCTTGAC CAAGACGCAA 
CCCAGAGGCC CCCACTTTTC AAGTGTGTAT GGCAAGCCTG TGATAGCTGC TGCCCAGAAT 
CCACAACAGC ACCCAGAGAA CATTTACTCC TGTAGCCAGG GGAAGCCTGG CAGTCCGGAG 
CCCGAGACAG AGACCGTTTC TTCAGTTCAT GAGAGCCATG AAAACGAAAG GATTCCTCGA 
CCACTCAGCC CAACAAAATT ACTGCCTTTC TTGTCTAACC CTTATCGAAA CCAGAGCGAT 
GCTGACTTAG AAGCCCTGAG GAAAAAATTG TCGAATGCAC CACGGCCACT AAAGAAACGT 
AGCTCCATTA CAGAACCAGA AGGCCCTAAT GGGCCAAATA TTCAGAAACT TTTGTATCAG 
AGGACCACCA TAGCTGCCAT GGAGACCATC TCAGTCCCCT CACACCCATC TAAGTCACCA 
GGCTCAGTGA CTGTCAATCC AGAGAGCTCC GTTGAAATCC CAAATCCATA TTTACATGTG 
GAGCCAGAGA AGGAGGTGGG CTCTTTAGTC CCTGAACCAC TGTCCCCAGA GGATATGGGG 
AGTGCCAGTA CGGAGAACAG TGACGTGCCA GCTCCTTCTG CAGGCCTTGA GTATGTGTCT 
GAGGGAGTCA CAGACAGCAG TACCAATCTG CAGAATAACG TAGAAGAAAC AAACCCAGAG 
GCTCCCCACT TACTTGAAGT GTACCTAGAA GAATACCCCC CATACCCACC CCCTCCATAC 
CCATCTGGGG AGCCAGAGGT GTCCGAAGAA GACTCCGCAC GTATGCGCCC ACCTGAAATC 
ACCGGGCAGG TGTCTCTGCC TCCTGGCAAA AGGACAAACT TGCGGAAAAC TGGCTCCGAG 
CGGATTGCTC ACGGGATGAG GGTGAAATTC AACCCCCTTG CTTTGCTGCT AGATTCATCT 
CTGGAGGGAG AGTTTGATCT TGTACAGAGA ATTATCTATG AGGTTGATGA CCCAAGCCTA 
CCAAATGATG AGGGCATCAC AGCTCTTCAT AATGCTGTGT GTGCAGGCCA CACAGAAATT 
GTGAAGTTCC TGGTACAGTT CGGTGTGAAT GTAAATGCAG CAGATAGTGA TGGATGGACG 
CCATTGCATT GTGCTGCCTC CTGCAACAAT GTCCAAGTGT GTAAGTTCCT GGTGGAGTCT 
GGAGCAGCTG TGTTTGCTAT GACCTACAGT GACATGCAGA CTGCTGCAGA CAAGTGCGAG 
GAAATGGAGG AAGGCTACAC GCAGTGCTCC CAGTTTCTCT ATGGCGTTCA GGAGAAGATG 
GGCATAATGA ACAAAGGCGT CATTTATGCA CTGTGGGATT ACGAGCCGCA GCATGACGAT 
GAGCTGCTCA TGAAAGAAGG AGATTGCATG ACCGTCATCC GCAGAGAAGA TGAAGAGGAG 
ATCGAGTGGT GGTGGGCGCG CCTTAACGAT AAGGAAGGAT ATGTTCCACG CAACTTGCTA 
GGACTATACC CAAGAATTAA ACCAAGACAA AGGAGCTTGG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

?N-ASPP2, a novel isoform of the ASPP2 tumor suppressor, promotes cellular survival.
Biochemical and biophysical research communications482(4)1271-1277(2017 Jan)
Van Hook K,Wang Z,Chen D,Nold C,Zhu Z,Anur P,Lee HJ,Yu Z,Sheppard B,Dai MS,Sears R,Spellman P,Lopez CD

ASPP2 deficiency causes features of 1q41q42 microdeletion syndrome.
Cell death and differentiation23(12)1973-1984(2016 Dec)
Zak J,Vives V,Szumska D,Vernet A,Schneider JE,Miller P,Slee EA,Joss S,Lacassie Y,Chen E,Escobar LF,Tucker M,Aylsworth AS,Dubbs HA,Collins AT,Andrieux J,Dieux-Coeslier A,Haberlandt E,Kotzot D,Scott DA,Parker MJ,Zakaria Z,Choy YS,Wieczorek D,Innes AM,Jun KR,Zinner S,Prin F,Lygate CA,Pretorius P,Rosenfeld JA,Mohun TJ,Lu X

ASPP2 involvement in p53-mediated HIV-1 envelope glycoprotein gp120 neurotoxicity in mice cerebrocortical neurons.
Scientific reports633378(2016 Sep)
Liu Z,Zang Y,Qiao L,Liu K,Ouyang Y,Zhang Y,Chen D

ASPP2 Is a Novel Pan-Ras Nanocluster Scaffold.
PloS one11(7)e0159677(2016)
Posada IM,Serulla M,Zhou Y,Oetken-Lindholm C,Abankwa D,Lectez B

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Trp53bp2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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