Bex1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Bex1
Entrez Gene ID	19716
Full Name	brain expressed X-linked 1
Synonyms	AA407839,AU018692,Bex4,Rex3
General protein information	Preferred Names brain expressed X-linked 1 Names protein BEX1 REX-3 brain expressed gene 1 brain-expressed X-linked protein 1 homolog reduced expression 3 reduced expression protein 3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: X Map Location: X F1\|X 57.4 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_009052.2	NP_033078.2	protein BEX1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	LOC100684429	XP_003435428.1
Mus musculus (house mouse)	Bex1	NP_033078.2
	LOC694924	XP_001083571.2

Gene Ontology
Bibliography

Related articles in PubMed

BEX1 is an RNA-dependent mediator of cardiomyopathy.
Accornero F, Schips TG, Petrosino JM, Gu SQ, Kanisicak O, van Berlo JH, Molkentin JD
Nature communications8(1)1875(2017 Nov)

The brain expressed x-linked gene 1 (Bex1) regulates myoblast fusion.
Jiang C, Wang JH, Yue F, Kuang S
Developmental biology409(1)16-25(2016 Jan)

Brain expressed and X-linked (Bex) proteins are intrinsically disordered proteins (IDPs) and form new signaling hubs.
Fernandez EM, D?az-Ceso MD, Vilar M
PloS one10(1)e0117206(2015)

Gene targeting study reveals unexpected expression of brain-expressed X-linked 2 in endocrine and tissue stem/progenitor cells in mice.
Ito K, Yamazaki S, Yamamoto R, Tajima Y, Yanagida A, Kobayashi T, Kato-Itoh M, Kakuta S, Iwakura Y, Nakauchi H, Kamiya A
The Journal of biological chemistry289(43)29892-911(2014 Oct)

Elf5 counteracts precocious trophoblast differentiation by maintaining Sox2 and 3 and inhibiting Hand1 expression.
Pearton DJ, Smith CS, Redgate E, van Leeuwen J, Donnison M, Pfeffer PL
Developmental biology392(2)344-57(2014 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results elucidate a novel role of Bex1 in myogenesis through regulating myoblast fusion.
Title: The brain expressed x-linked gene 1 (Bex1) regulates myoblast fusion.

Bex family members play important roles in the formation of protein network hubs.
Title: Brain expressed and X-linked (Bex) proteins are intrinsically disordered proteins (IDPs) and form new signaling hubs.

Bex1 protein is over-expressed as a result of peripheral axonal damage and antagonizes the axon outgrowth inhibitory effect of myelin-associated glycoprotein.
Title: Bex1 is involved in the regeneration of axons after injury.

Thus, our results provide the first evidence that Bex1-KO mice show altered muscle regeneration, and allow us to propose that the interaction of Bex1 with Ca(2+)/CaM may be involved in skeletal muscle regeneration.
Title: Bex1 knock out mice show altered skeletal muscle regeneration.

Bex1 and 2 have been characterized as interacting partners of the olfactory marker protein (OMP). Bex immunoreactivity (ir) was primarily localized to neuronal cells within several regions of the brain.
Title: Immunolocalization of Bex protein in the mouse brain and olfactory system.

The following Bex1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bex1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu03420	NM_009052.2 Latest version!	Mus musculus brain expressed X-linked 1 (Bex1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Bex1 ( NM_009052.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033078.2 Mus musculus brain expressed X-linked 1 (Bex1), mRNA.

Price & Availability↑

CloneID	OMu03420
Clone ID Related Accession (Same CDS sequence)	NM_009052.2
Accession Version	NM_009052.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 387bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	protein BEX1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY115963.1, CB194115.1 and AF097438.1. On May 6, 2004 this sequence version replaced NM_009052.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CX767802.1, CB192839.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849376 [ECO:0000348] ##Evidence-Data-END##

ATGGAGTCCA AAGATCAAGG CGTGAAAAAT CTCAACATGG AGAATGACCA TCAGAAAAAG 
GAGGAGAAGG AAGAAAAGCC ACAAGATACC ATCAGAAGGG AGCCAGCTGT GGCCCTGACC 
TCCGAGGCTG GCAAAAACTG TGCACCTAGA GGAGGTCGCA GGCGGTTCCG GGTTCGGCAG 
CCCATCGCTC ACTATAGATG GGACCTGATG CAGAGGGTTG GGGAGCCCCA GGGAAGGATG 
AGAGAGGAGA ACGTACAGAG GTTTGGGGGT GATGTGAGAC AGCTCATGGA GAAGCTGAGG 
GAAAGGCAGC TGAGCCACAG CCTGCGGGCG GTTAGCACTG ACCCGCCTCA TCATGACCAC 
CATGATGAGT TTTGCCTCAT GCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033078.2
CDS	260..646
Translation	MESKDQGVKNLNMENDHQKKEEKEEKPQDTIRREPAVALTSEAGKNCAPRGGRRRFRVRQPIAHYRWDLMQRVGEPQGRMREENVQRFGGDVRQLMEKLRERQLSHSLRAVSTDPPHHDHHDEFCLMP

Target ORF information:

RefSeq Version	NM_009052.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus brain expressed X-linked 1 (Bex1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009052.2

ORF Insert Sequence:

ATGGAGTCCA AAGATCAAGG CGTGAAAAAT CTCAACATGG AGAATGACCA TCAGAAAAAG 
GAGGAGAAGG AAGAAAAGCC ACAAGATACC ATCAGAAGGG AGCCAGCTGT GGCCCTGACC 
TCCGAGGCTG GCAAAAACTG TGCACCTAGA GGAGGTCGCA GGCGGTTCCG GGTTCGGCAG 
CCCATCGCTC ACTATAGATG GGACCTGATG CAGAGGGTTG GGGAGCCCCA GGGAAGGATG 
AGAGAGGAGA ACGTACAGAG GTTTGGGGGT GATGTGAGAC AGCTCATGGA GAAGCTGAGG 
GAAAGGCAGC TGAGCCACAG CCTGCGGGCG GTTAGCACTG ACCCGCCTCA TCATGACCAC 
CATGATGAGT TTTGCCTCAT GCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

BEX1 is an RNA-dependent mediator of cardiomyopathy.
Nature communications8(1)1875(2017 Nov)
Accornero F,Schips TG,Petrosino JM,Gu SQ,Kanisicak O,van Berlo JH,Molkentin JD

The brain expressed x-linked gene 1 (Bex1) regulates myoblast fusion.
Developmental biology409(1)16-25(2016 Jan)
Jiang C,Wang JH,Yue F,Kuang S

Brain expressed and X-linked (Bex) proteins are intrinsically disordered proteins (IDPs) and form new signaling hubs.
PloS one10(1)e0117206(2015)
Fernandez EM,D?az-Ceso MD,Vilar M

Gene targeting study reveals unexpected expression of brain-expressed X-linked 2 in endocrine and tissue stem/progenitor cells in mice.
The Journal of biological chemistry289(43)29892-911(2014 Oct)
Ito K,Yamazaki S,Yamamoto R,Tajima Y,Yanagida A,Kobayashi T,Kato-Itoh M,Kakuta S,Iwakura Y,Nakauchi H,Kamiya A

Elf5 counteracts precocious trophoblast differentiation by maintaining Sox2 and 3 and inhibiting Hand1 expression.
Developmental biology392(2)344-57(2014 Aug)
Pearton DJ,Smith CS,Redgate E,van Leeuwen J,Donnison M,Pfeffer PL

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Bex1 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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