PLA2G15 cDNA ORF clone, Mus musculus(House mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	PLA2G15
Entrez Gene ID	192654
Full Name	phospholipase A2, group XV
Synonyms	ACS,C87498,LLPL,Lpla2,Lypla3
General protein information	Preferred Names phospholipase A2, group XV Names group XV phospholipase A2 1-O-acylceramide synthase LCAT-like lysophospholipase lysophospholipase 3 lysosomal phospholipase A2
Gene Type	protein-coding
Organism	Mus musculus(House mouse)
Genome	Chromosome: 8 Map Location: 8\|8 D3

mRNA and Protein(s)

mRNA	Protein	Name
NM_133792.3	NP_598553.1	group XV phospholipase A2 isoform 1 precursor
NM_133792.2	NP_598553.1	group XV phospholipase A2 precursor
NM_001357319.1	NP_001344248.1	group XV phospholipase A2 isoform 2 precursor
XM_006530772.1	XP_006530835.1	group XV phospholipase A2 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	PLA2G15	NP_036452.1
	PLA2G15	XP_001098709.2
Drosophila melanogaster (fruit fly)	CG31683	NP_001260626.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008990	XP_552886.2
Pan troglodytes (chimpanzee)	PLA2G15	XP_001167383.1
Mus musculus (house mouse)	Pla2g15	NP_598553.1
Gallus gallus (chicken)	PLA2G15	XP_001231519.1
Danio rerio (zebrafish)	pla2g15	XP_003201435.2
Xenopus tropicalis (tropical clawed frog)	pla2g15	XP_004913556.1
Canis lupus familiaris (dog)	PLA2G15	NP_001002940.1
Bos taurus (cattle)	PLA2G15	NP_776985.2
Drosophila melanogaster (fruit fly)	CG18858	NP_001260628.1
Caenorhabditis elegans (roundworm)	M05B5.4	NP_492033.1
Oryza sativa (rice)	Os03g0730000	NP_001051160.2
Rattus norvegicus (Norway rat)	Pla2g15	NP_001004277.1
Arabidopsis thaliana (thale cress)	AT1G27480	NP_564286.1

Gene Ontology
Bibliography

Related articles in PubMed

Constraint and divergence of global gene expression in the mammalian embryo.
Spies N, Smith CL, Rodriguez JM, Baker JC, Batzoglou S, Sidow A
eLife4e05538(2015 Apr)

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Abonnenc M, Nabeebaccus AA, Mayr U, Barallobre-Barreiro J, Dong X, Cuello F, Sur S, Drozdov I, Langley SR, Lu R, Stathopoulou K, Didangelos A, Yin X, Zimmermann WH, Shah AM, Zampetaki A, Mayr M
Circulation research113(10)1138-47(2013 Oct)

Role for lysosomal phospholipase A2 in iNKT cell-mediated CD1d recognition.
Paduraru C, Bezbradica JS, Kunte A, Kelly R, Shayman JA, Veerapen N, Cox LR, Besra GS, Cresswell P
Proceedings of the National Academy of Sciences of the United States of America110(13)5097-102(2013 Mar)

A mouse knockout library for secreted and transmembrane proteins.
Tang T, Li L, Tang J, Li Y, Lin WY, Martin F, Grant D, Solloway M, Parker L, Ye W, Forrest W, Ghilardi N, Oravecz T, Platt KA, Rice DS, Hansen GM, Abuin A, Eberhart DE, Godowski P, Holt KH, Peterson A, Zambrowicz BP, de Sauvage FJ
Nature biotechnology28(7)749-55(2010 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

LPLA2 plays a role in the generation of CD1d complexes with thymic lipids required for the normal selection and maturation of iNKT cells.
Title: Role for lysosomal phospholipase A2 in iNKT cell-mediated CD1d recognition.

The secretion and uptake of lysosomal phospholipase A2 by alveolar macrophages
Title: The secretion and uptake of lysosomal phospholipase A2 by alveolar macrophages.

Lpla2 has broad positional specificity for the sn-1 and sn-2 acyl groups in phosphatidylcholine and phosphatidylethanolamine
Title: Positional specificity of lysosomal phospholipase A2.

A deficiency of lysosomal phospholipase A2 results in foam cell formation, surfactant lipid accumulation, splenomegaly, and phospholipidosis in mice.
Title: Lysosomal phospholipase A2 and phospholipidosis.

identification of the catalytic triad and the role of cysteine residues in lysosomal phospholipase A2
Title: Structure and function of lysosomal phospholipase A2: identification of the catalytic triad and the role of cysteine residues.

The following PLA2G15 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PLA2G15 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu10222	NM_133792.3 Latest version!	Mus musculus phospholipase A2, group XV (Pla2g15), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
OMu41292	NM_001357319.1 Latest version!	Mus musculus phospholipase A2, group XV (Pla2g15), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu41292	XM_006530772.1 Latest version!	Mus musculus phospholipase A2, group XV (Pla2g15), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OMu10222	NM_133792.2	Mus musculus phospholipase A2, group XV (Pla2g15), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PLA2G15 ( NM_133792.3 ) cDNA ORF clone, Mus musculus(House mouse) -> NP_598553.1 Mus musculus phospholipase A2, group XV (Pla2g15), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu10222
Clone ID Related Accession (Same CDS sequence)	NM_133792.3 , NM_133792.2
Accession Version	NM_133792.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1239bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Mus musculus(house mouse)
Product	group XV phospholipase A2 isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC133195.4, AK085194.1 and BM226964.2. On Oct 25, 2017 this sequence version replaced NM_133792.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC019373.1, AK155004.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATCGCC ATCTCTGCAC CTGTCGCGAG ACCCAGCTCC GGAGTGGCCT CCTGTTACCT 
CTGTTTCTAC TAATGATGCT GGCAGACCTG ACGCTCCCGG CCCAACGTCA CCCCCCGGTG 
GTGCTGGTGC CTGGTGATTT GGGTAACCAG TTGGAAGCAA AGCTGGATAA GCCAAAGGTT 
GTACACTACC TTTGCTCCAA GAAGACGGAC AGCTACTTCA CACTCTGGCT GAATCTGGAA 
CTGCTTCTGC CTGTTATCAT TGACTGCTGG ATTGACAATA TCAGGCTGGT TTACAACAGA 
ACATCTCGGG CCACCCAGTT TCCCGATGGT GTGGACGTGC GTGTCCCTGG CTTTGGGGAA 
ACATTTTCTA TGGAATTCCT AGACCCCAGC AAGAGGAATG TGGGTTCCTA TTTCTACACT 
ATGGTGGAGA GCCTTGTGGG CTGGGGCTAC ACACGGGGTG AAGACGTTCG AGGTGCTCCC 
TATGATTGGC GGCGAGCCCC AAATGAAAAC GGGCCCTACT TCTTGGCCCT GCGAGAGATG 
ATCGAGGAGA TGTACCAGAT GTATGGGGGC CCCGTGGTGC TGGTCGCCCA CAGCATGGGC 
AACGTGTACA TGCTCTACTT TCTGCAGCGG CAGCCACAAG TCTGGAAGGA CAAATATATC 
CATGCCTTCG TCTCACTGGG GGCGCCCTGG GGGGGCGTGG CCAAGACGCT GCGTGTCCTG 
GCCTCAGGAG ACAACAATCG CATTCCCGTC ATTGGGCCAC TGAAGATCCG GGAACAGCAG 
CGATCTGCCG TCTCTACCAG CTGGCTACTG CCATACAACC ACACTTGGTC ACATGAAAAG 
GTATTTGTAT ACACACCCAC GACTAACTAC ACGCTCCGGG ACTATCACCG GTTCTTCCGG 
GACATCGGTT TCGAAGATGG CTGGTTCATG CGGCAGGACA CAGAAGGGCT GGTTGAAGCC 
ATGACGCCAC CCGGGGTGGA GCTGCACTGC TTGTATGGCA CTGGTGTTCC CACGCCAAAC 
TCTTTCTACT ACGAGAGCTT TCCTGATCGG GACCCCAAAA TCTGCTTCGG CGATGGTGAC 
GGCACGGTGA ACCTGGAGAG CGTCCTGCAG TGCCAAGCCT GGCAGAGCCG CCAAGAGCAC 
AGAGTATCAT TGCAGGAGCT GCCGGGAAGC GAGCACATTG AGATGCTAGC CAATGCCACC 
ACCTTGGCTT ATCTGAAACG TGTGCTTCTG GAACCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598553.1
CDS	134..1372
Translation	MDRHLCTCRETQLRSGLLLPLFLLMMLADLTLPAQRHPPVVLVPGDLGNQLEAKLDKPKVVHYLCSKKTDSYFTLWLNLELLLPVIIDCWIDNIRLVYNRTSRATQFPDGVDVRVPGFGETFSMEFLDPSKRNVGSYFYTMVESLVGWGYTRGEDVRGAPYDWRRAPNENGPYFLALREMIEEMYQMYGGPVVLVAHSMGNVYMLYFLQRQPQVWKDKYIHAFVSLGAPWGGVAKTLRVLASGDNNRIPVIGPLKIREQQRSAVSTSWLLPYNHTWSHEKVFVYTPTTNYTLRDYHRFFRDIGFEDGWFMRQDTEGLVEAMTPPGVELHCLYGTGVPTPNSFYYESFPDRDPKICFGDGDGTVNLESVLQCQAWQSRQEHRVSLQELPGSEHIEMLANATTLAYLKRVLLEP

Target ORF information:

RefSeq Version	NM_133792.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus phospholipase A2, group XV (Pla2g15), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133792.3

ORF Insert Sequence:

ATGGATCGCC ATCTCTGCAC CTGTCGCGAG ACCCAGCTCC GGAGTGGCCT CCTGTTACCT 
CTGTTTCTAC TAATGATGCT GGCAGACCTG ACGCTCCCGG CCCAACGTCA CCCCCCGGTG 
GTGCTGGTGC CTGGTGATTT GGGTAACCAG TTGGAAGCAA AGCTGGATAA GCCAAAGGTT 
GTACACTACC TTTGCTCCAA GAAGACGGAC AGCTACTTCA CACTCTGGCT GAATCTGGAA 
CTGCTTCTGC CTGTTATCAT TGACTGCTGG ATTGACAATA TCAGGCTGGT TTACAACAGA 
ACATCTCGGG CCACCCAGTT TCCCGATGGT GTGGACGTGC GTGTCCCTGG CTTTGGGGAA 
ACATTTTCTA TGGAATTCCT AGACCCCAGC AAGAGGAATG TGGGTTCCTA TTTCTACACT 
ATGGTGGAGA GCCTTGTGGG CTGGGGCTAC ACACGGGGTG AAGACGTTCG AGGTGCTCCC 
TATGATTGGC GGCGAGCCCC AAATGAAAAC GGGCCCTACT TCTTGGCCCT GCGAGAGATG 
ATCGAGGAGA TGTACCAGAT GTATGGGGGC CCCGTGGTGC TGGTCGCCCA CAGCATGGGC 
AACGTGTACA TGCTCTACTT TCTGCAGCGG CAGCCACAAG TCTGGAAGGA CAAATATATC 
CATGCCTTCG TCTCACTGGG GGCGCCCTGG GGGGGCGTGG CCAAGACGCT GCGTGTCCTG 
GCCTCAGGAG ACAACAATCG CATTCCCGTC ATTGGGCCAC TGAAGATCCG GGAACAGCAG 
CGATCTGCCG TCTCTACCAG CTGGCTACTG CCATACAACC ACACTTGGTC ACATGAAAAG 
GTATTTGTAT ACACACCCAC GACTAACTAC ACGCTCCGGG ACTATCACCG GTTCTTCCGG 
GACATCGGTT TCGAAGATGG CTGGTTCATG CGGCAGGACA CAGAAGGGCT GGTTGAAGCC 
ATGACGCCAC CCGGGGTGGA GCTGCACTGC TTGTATGGCA CTGGTGTTCC CACGCCAAAC 
TCTTTCTACT ACGAGAGCTT TCCTGATCGG GACCCCAAAA TCTGCTTCGG CGATGGTGAC 
GGCACGGTGA ACCTGGAGAG CGTCCTGCAG TGCCAAGCCT GGCAGAGCCG CCAAGAGCAC 
AGAGTATCAT TGCAGGAGCT GCCGGGAAGC GAGCACATTG AGATGCTAGC CAATGCCACC 
ACCTTGGCTT ATCTGAAACG TGTGCTTCTG GAACCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLA2G15 ( NM_133792.2 ) cDNA ORF clone, Mus musculus(House mouse) -> NP_598553.1 Mus musculus phospholipase A2, group XV (Pla2g15), mRNA.

Price & Availability↑

CloneID	OMu10222
Clone ID Related Accession (Same CDS sequence)	NM_133792.3 , NM_133792.2
Accession Version	NM_133792.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1239bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-04-24
Organism	Mus musculus(House mouse)
Product	group XV phospholipase A2 precursor
Comment	PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC019373.1. On Jun 9, 2003 this sequence version replaced NM_133792.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC019373.1, AK155004.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGATCGCC ATCTCTGCAC CTGTCGCGAG ACCCAGCTCC GGAGTGGCCT CCTGTTACCT 
CTGTTTCTAC TAATGATGCT GGCAGACCTG ACGCTCCCGG CCCAACGTCA CCCCCCGGTG 
GTGCTGGTGC CTGGTGATTT GGGTAACCAG TTGGAAGCAA AGCTGGATAA GCCAAAGGTT 
GTACACTACC TTTGCTCCAA GAAGACGGAC AGCTACTTCA CACTCTGGCT GAATCTGGAA 
CTGCTTCTGC CTGTTATCAT TGACTGCTGG ATTGACAATA TCAGGCTGGT TTACAACAGA 
ACATCTCGGG CCACCCAGTT TCCCGATGGT GTGGACGTGC GTGTCCCTGG CTTTGGGGAA 
ACATTTTCTA TGGAATTCCT AGACCCCAGC AAGAGGAATG TGGGTTCCTA TTTCTACACT 
ATGGTGGAGA GCCTTGTGGG CTGGGGCTAC ACACGGGGTG AAGACGTTCG AGGTGCTCCC 
TATGATTGGC GGCGAGCCCC AAATGAAAAC GGGCCCTACT TCTTGGCCCT GCGAGAGATG 
ATCGAGGAGA TGTACCAGAT GTATGGGGGC CCCGTGGTGC TGGTCGCCCA CAGCATGGGC 
AACGTGTACA TGCTCTACTT TCTGCAGCGG CAGCCACAAG TCTGGAAGGA CAAATATATC 
CATGCCTTCG TCTCACTGGG GGCGCCCTGG GGGGGCGTGG CCAAGACGCT GCGTGTCCTG 
GCCTCAGGAG ACAACAATCG CATTCCCGTC ATTGGGCCAC TGAAGATCCG GGAACAGCAG 
CGATCTGCCG TCTCTACCAG CTGGCTACTG CCATACAACC ACACTTGGTC ACATGAAAAG 
GTATTTGTAT ACACACCCAC GACTAACTAC ACGCTCCGGG ACTATCACCG GTTCTTCCGG 
GACATCGGTT TCGAAGATGG CTGGTTCATG CGGCAGGACA CAGAAGGGCT GGTTGAAGCC 
ATGACGCCAC CCGGGGTGGA GCTGCACTGC TTGTATGGCA CTGGTGTTCC CACGCCAAAC 
TCTTTCTACT ACGAGAGCTT TCCTGATCGG GACCCCAAAA TCTGCTTCGG CGATGGTGAC 
GGCACGGTGA ACCTGGAGAG CGTCCTGCAG TGCCAAGCCT GGCAGAGCCG CCAAGAGCAC 
AGAGTATCAT TGCAGGAGCT GCCGGGAAGC GAGCACATTG AGATGCTAGC CAATGCCACC 
ACCTTGGCTT ATCTGAAACG TGTGCTTCTG GAACCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598553.1
CDS	89..1327
Translation	MDRHLCTCRETQLRSGLLLPLFLLMMLADLTLPAQRHPPVVLVPGDLGNQLEAKLDKPKVVHYLCSKKTDSYFTLWLNLELLLPVIIDCWIDNIRLVYNRTSRATQFPDGVDVRVPGFGETFSMEFLDPSKRNVGSYFYTMVESLVGWGYTRGEDVRGAPYDWRRAPNENGPYFLALREMIEEMYQMYGGPVVLVAHSMGNVYMLYFLQRQPQVWKDKYIHAFVSLGAPWGGVAKTLRVLASGDNNRIPVIGPLKIREQQRSAVSTSWLLPYNHTWSHEKVFVYTPTTNYTLRDYHRFFRDIGFEDGWFMRQDTEGLVEAMTPPGVELHCLYGTGVPTPNSFYYESFPDRDPKICFGDGDGTVNLESVLQCQAWQSRQEHRVSLQELPGSEHIEMLANATTLAYLKRVLLEP

Target ORF information:

RefSeq Version	NM_133792.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus phospholipase A2, group XV (Pla2g15), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133792.2

ORF Insert Sequence:

ATGGATCGCC ATCTCTGCAC CTGTCGCGAG ACCCAGCTCC GGAGTGGCCT CCTGTTACCT 
CTGTTTCTAC TAATGATGCT GGCAGACCTG ACGCTCCCGG CCCAACGTCA CCCCCCGGTG 
GTGCTGGTGC CTGGTGATTT GGGTAACCAG TTGGAAGCAA AGCTGGATAA GCCAAAGGTT 
GTACACTACC TTTGCTCCAA GAAGACGGAC AGCTACTTCA CACTCTGGCT GAATCTGGAA 
CTGCTTCTGC CTGTTATCAT TGACTGCTGG ATTGACAATA TCAGGCTGGT TTACAACAGA 
ACATCTCGGG CCACCCAGTT TCCCGATGGT GTGGACGTGC GTGTCCCTGG CTTTGGGGAA 
ACATTTTCTA TGGAATTCCT AGACCCCAGC AAGAGGAATG TGGGTTCCTA TTTCTACACT 
ATGGTGGAGA GCCTTGTGGG CTGGGGCTAC ACACGGGGTG AAGACGTTCG AGGTGCTCCC 
TATGATTGGC GGCGAGCCCC AAATGAAAAC GGGCCCTACT TCTTGGCCCT GCGAGAGATG 
ATCGAGGAGA TGTACCAGAT GTATGGGGGC CCCGTGGTGC TGGTCGCCCA CAGCATGGGC 
AACGTGTACA TGCTCTACTT TCTGCAGCGG CAGCCACAAG TCTGGAAGGA CAAATATATC 
CATGCCTTCG TCTCACTGGG GGCGCCCTGG GGGGGCGTGG CCAAGACGCT GCGTGTCCTG 
GCCTCAGGAG ACAACAATCG CATTCCCGTC ATTGGGCCAC TGAAGATCCG GGAACAGCAG 
CGATCTGCCG TCTCTACCAG CTGGCTACTG CCATACAACC ACACTTGGTC ACATGAAAAG 
GTATTTGTAT ACACACCCAC GACTAACTAC ACGCTCCGGG ACTATCACCG GTTCTTCCGG 
GACATCGGTT TCGAAGATGG CTGGTTCATG CGGCAGGACA CAGAAGGGCT GGTTGAAGCC 
ATGACGCCAC CCGGGGTGGA GCTGCACTGC TTGTATGGCA CTGGTGTTCC CACGCCAAAC 
TCTTTCTACT ACGAGAGCTT TCCTGATCGG GACCCCAAAA TCTGCTTCGG CGATGGTGAC 
GGCACGGTGA ACCTGGAGAG CGTCCTGCAG TGCCAAGCCT GGCAGAGCCG CCAAGAGCAC 
AGAGTATCAT TGCAGGAGCT GCCGGGAAGC GAGCACATTG AGATGCTAGC CAATGCCACC 
ACCTTGGCTT ATCTGAAACG TGTGCTTCTG GAACCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLA2G15 ( NM_001357319.1 ) cDNA ORF clone, Mus musculus(House mouse) -> NP_001344248.1 Mus musculus phospholipase A2, group XV (Pla2g15), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu41292
Clone ID Related Accession (Same CDS sequence)	NM_001357319.1 , XM_006530772.1
Accession Version	NM_001357319.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 711bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Mus musculus(house mouse)
Product	group XV phospholipase A2 isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC133195.4, AK028614.1 and BM226964.2. On Oct 25, 2017 this sequence version replaced XM_006530772.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK028614.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATCGCC ATCTCTGCAC CTGTCGCGAG ACCCAGCTCC GGAGTGGCCT CCTGTTACCT 
CTGTTTCTAC TAATGATGCT GGCAGACCTG ACGCTCCCGG CCCAACGTCA CCCCCCGGTG 
GTGCTGGTGC CTGGTGATTT GGGTAACCAG TTGGAAGCAA AGCTGGATAA GCCAAAGGTT 
GTACACTACC TTTGCTCCAA GAAGACGGAC AGCTACTTCA CACTCTGGCT GAATCTGGAA 
CTGCTTCTGC CTGTTATCAT TGACTGCTGG ATTGACAATA TCAGGCTGGT TTACAACAGA 
ACATCTCGGG CCACCCAGTT TCCCGATGGT GTGGACGTGC GTGTCCCTGG CTTTGGGGAA 
ACATTTTCTA TGGAATTCCT AGACCCCAGC AAGAGGAATG TGGGTTCCTA TTTCTACACT 
ATGGTGGAGA GCCTTGTGGG CTGGGGCTAC ACACGGGGTG AAGACGTTCG AGGTGCTCCC 
TATGATTGGC GGCGAGCCCC AACGGCAGCC ACAAGTCTGG AAGGACAAAT ATATCCATGC 
CTTCGTCTCA CTGGGGGCGC CCTGGGGGGG CGTGGCCAAG ACGCTGCGTG TCCTGGCCTC 
AGGAGACAAC AATCGCATTC CCGTCATTGG GCCACTGAAG ATCCGGGAAC AGCAGCGATC 
TGCCGTCTCT ACCAGCTGGC TACTGCCATA CAACCACACT TGGTCACATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001344248.1
CDS	134..844
Translation	MDRHLCTCRETQLRSGLLLPLFLLMMLADLTLPAQRHPPVVLVPGDLGNQLEAKLDKPKVVHYLCSKKTDSYFTLWLNLELLLPVIIDCWIDNIRLVYNRTSRATQFPDGVDVRVPGFGETFSMEFLDPSKRNVGSYFYTMVESLVGWGYTRGEDVRGAPYDWRRAPTAATSLEGQIYPCLRLTGGALGGRGQDAACPGLRRQQSHSRHWATEDPGTAAICRLYQLATAIQPHLVT

Target ORF information:

RefSeq Version	NM_001357319.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus phospholipase A2, group XV (Pla2g15), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001357319.1

ORF Insert Sequence:

ATGGATCGCC ATCTCTGCAC CTGTCGCGAG ACCCAGCTCC GGAGTGGCCT CCTGTTACCT 
CTGTTTCTAC TAATGATGCT GGCAGACCTG ACGCTCCCGG CCCAACGTCA CCCCCCGGTG 
GTGCTGGTGC CTGGTGATTT GGGTAACCAG TTGGAAGCAA AGCTGGATAA GCCAAAGGTT 
GTACACTACC TTTGCTCCAA GAAGACGGAC AGCTACTTCA CACTCTGGCT GAATCTGGAA 
CTGCTTCTGC CTGTTATCAT TGACTGCTGG ATTGACAATA TCAGGCTGGT TTACAACAGA 
ACATCTCGGG CCACCCAGTT TCCCGATGGT GTGGACGTGC GTGTCCCTGG CTTTGGGGAA 
ACATTTTCTA TGGAATTCCT AGACCCCAGC AAGAGGAATG TGGGTTCCTA TTTCTACACT 
ATGGTGGAGA GCCTTGTGGG CTGGGGCTAC ACACGGGGTG AAGACGTTCG AGGTGCTCCC 
TATGATTGGC GGCGAGCCCC AACGGCAGCC ACAAGTCTGG AAGGACAAAT ATATCCATGC 
CTTCGTCTCA CTGGGGGCGC CCTGGGGGGG CGTGGCCAAG ACGCTGCGTG TCCTGGCCTC 
AGGAGACAAC AATCGCATTC CCGTCATTGG GCCACTGAAG ATCCGGGAAC AGCAGCGATC 
TGCCGTCTCT ACCAGCTGGC TACTGCCATA CAACCACACT TGGTCACATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLA2G15 ( XM_006530772.1 ) cDNA ORF clone, Mus musculus(House mouse) -> XP_006530835.1 Mus musculus phospholipase A2, group XV (Pla2g15), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu41292
Clone ID Related Accession (Same CDS sequence)	NM_001357319.1 , XM_006530772.1
Accession Version	XM_006530772.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 711bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(House mouse)
Product	group XV phospholipase A2 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000074.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATCGCC ATCTCTGCAC CTGTCGCGAG ACCCAGCTCC GGAGTGGCCT CCTGTTACCT 
CTGTTTCTAC TAATGATGCT GGCAGACCTG ACGCTCCCGG CCCAACGTCA CCCCCCGGTG 
GTGCTGGTGC CTGGTGATTT GGGTAACCAG TTGGAAGCAA AGCTGGATAA GCCAAAGGTT 
GTACACTACC TTTGCTCCAA GAAGACGGAC AGCTACTTCA CACTCTGGCT GAATCTGGAA 
CTGCTTCTGC CTGTTATCAT TGACTGCTGG ATTGACAATA TCAGGCTGGT TTACAACAGA 
ACATCTCGGG CCACCCAGTT TCCCGATGGT GTGGACGTGC GTGTCCCTGG CTTTGGGGAA 
ACATTTTCTA TGGAATTCCT AGACCCCAGC AAGAGGAATG TGGGTTCCTA TTTCTACACT 
ATGGTGGAGA GCCTTGTGGG CTGGGGCTAC ACACGGGGTG AAGACGTTCG AGGTGCTCCC 
TATGATTGGC GGCGAGCCCC AACGGCAGCC ACAAGTCTGG AAGGACAAAT ATATCCATGC 
CTTCGTCTCA CTGGGGGCGC CCTGGGGGGG CGTGGCCAAG ACGCTGCGTG TCCTGGCCTC 
AGGAGACAAC AATCGCATTC CCGTCATTGG GCCACTGAAG ATCCGGGAAC AGCAGCGATC 
TGCCGTCTCT ACCAGCTGGC TACTGCCATA CAACCACACT TGGTCACATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006530835.1
CDS	137..847
Translation	MDRHLCTCRETQLRSGLLLPLFLLMMLADLTLPAQRHPPVVLVPGDLGNQLEAKLDKPKVVHYLCSKKTDSYFTLWLNLELLLPVIIDCWIDNIRLVYNRTSRATQFPDGVDVRVPGFGETFSMEFLDPSKRNVGSYFYTMVESLVGWGYTRGEDVRGAPYDWRRAPTAATSLEGQIYPCLRLTGGALGGRGQDAACPGLRRQQSHSRHWATEDPGTAAICRLYQLATAIQPHLVT

Target ORF information:

RefSeq Version	XM_006530772.1
Organism	Mus musculus(House mouse)
Definition	Mus musculus phospholipase A2, group XV (Pla2g15), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006530772.1

ORF Insert Sequence:

ATGGATCGCC ATCTCTGCAC CTGTCGCGAG ACCCAGCTCC GGAGTGGCCT CCTGTTACCT 
CTGTTTCTAC TAATGATGCT GGCAGACCTG ACGCTCCCGG CCCAACGTCA CCCCCCGGTG 
GTGCTGGTGC CTGGTGATTT GGGTAACCAG TTGGAAGCAA AGCTGGATAA GCCAAAGGTT 
GTACACTACC TTTGCTCCAA GAAGACGGAC AGCTACTTCA CACTCTGGCT GAATCTGGAA 
CTGCTTCTGC CTGTTATCAT TGACTGCTGG ATTGACAATA TCAGGCTGGT TTACAACAGA 
ACATCTCGGG CCACCCAGTT TCCCGATGGT GTGGACGTGC GTGTCCCTGG CTTTGGGGAA 
ACATTTTCTA TGGAATTCCT AGACCCCAGC AAGAGGAATG TGGGTTCCTA TTTCTACACT 
ATGGTGGAGA GCCTTGTGGG CTGGGGCTAC ACACGGGGTG AAGACGTTCG AGGTGCTCCC 
TATGATTGGC GGCGAGCCCC AACGGCAGCC ACAAGTCTGG AAGGACAAAT ATATCCATGC 
CTTCGTCTCA CTGGGGGCGC CCTGGGGGGG CGTGGCCAAG ACGCTGCGTG TCCTGGCCTC 
AGGAGACAAC AATCGCATTC CCGTCATTGG GCCACTGAAG ATCCGGGAAC AGCAGCGATC 
TGCCGTCTCT ACCAGCTGGC TACTGCCATA CAACCACACT TGGTCACATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Constraint and divergence of global gene expression in the mammalian embryo.
eLife4e05538(2015 Apr)
Spies N,Smith CL,Rodriguez JM,Baker JC,Batzoglou S,Sidow A

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Circulation research113(10)1138-47(2013 Oct)
Abonnenc M,Nabeebaccus AA,Mayr U,Barallobre-Barreiro J,Dong X,Cuello F,Sur S,Drozdov I,Langley SR,Lu R,Stathopoulou K,Didangelos A,Yin X,Zimmermann WH,Shah AM,Zampetaki A,Mayr M

Role for lysosomal phospholipase A2 in iNKT cell-mediated CD1d recognition.
Proceedings of the National Academy of Sciences of the United States of America110(13)5097-102(2013 Mar)
Paduraru C,Bezbradica JS,Kunte A,Kelly R,Shayman JA,Veerapen N,Cox LR,Besra GS,Cresswell P

A mouse knockout library for secreted and transmembrane proteins.
Nature biotechnology28(7)749-55(2010 Jul)
Tang T,Li L,Tang J,Li Y,Lin WY,Martin F,Grant D,Solloway M,Parker L,Ye W,Forrest W,Ghilardi N,Oravecz T,Platt KA,Rice DS,Hansen GM,Abuin A,Eberhart DE,Godowski P,Holt KH,Peterson A,Zambrowicz BP,de Sauvage FJ

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PLA2G15 cDNA ORF clone, Mus musculus(House mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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