Ptp4a1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ptp4a1
Entrez Gene ID	19243
Full Name	protein tyrosine phosphatase 4a1
Synonyms	AA415290,AU019864,C130021B01,Prl-1
General protein information	Preferred Names protein tyrosine phosphatase 4a1 Names protein tyrosine phosphatase type IVA 1 protein-tyrosine phosphatase of regenerating liver 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1\|1 A5-B

mRNA and Protein(s)

mRNA	Protein	Name
XM_006495799.2	XP_006495862.1	protein tyrosine phosphatase type IVA 1 isoform X1
XM_006495798.4	XP_006495861.1	protein tyrosine phosphatase type IVA 1 isoform X1
NM_011200.2	NP_035330.1	protein tyrosine phosphatase type IVA 1
XM_006495798.3	XP_006495861.1	protein tyrosine phosphatase type IVA 1 isoform X1
XM_006495799.3	XP_006495862.1	protein tyrosine phosphatase type IVA 1 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PTP4A1	NP_001233568.1
Rattus norvegicus (Norway rat)	Ptp4a1	NP_113767.1
	PTP4A1	XP_001083424.1
Danio rerio (zebrafish)	ptp4a1	NP_001007776.2
Bos taurus (cattle)	PTP4A1	NP_001193053.1
Gallus gallus (chicken)	PTP4A1	NP_001008461.1
Drosophila melanogaster (fruit fly)	PRL-1	NP_609780.1
Caenorhabditis elegans (roundworm)	prl-1	NP_508683.1
Xenopus tropicalis (tropical clawed frog)	ptp4a1	NP_001008023.1
Homo sapiens (human)	PTP4A1	NP_003454.1
Canis lupus familiaris (dog)	PTP4A1	XP_005627571.1
Mus musculus (house mouse)	Ptp4a1	NP_035330.1
Rattus norvegicus (Norway rat)	LOC102547074	XP_006244747.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008708	XP_314814.3

Gene Ontology
Bibliography

Related articles in PubMed

PTP4A1 promotes TGF? signaling and fibrosis in systemic sclerosis.
Sacchetti C, Bai Y, Stanford SM, Di Benedetto P, Cipriani P, Santelli E, Piera-Velazquez S, Chernitskiy V, Kiosses WB, Ceponis A, Kaestner KH, Boin F, Jimenez SA, Giacomelli R, Zhang ZY, Bottini N
Nature communications8(1)1060(2017 Oct)

Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.
Gim?nez-Mascarell P, Oyenarte I, Hardy S, Breiderhoff T, Stuiver M, Kostantin E, Diercks T, Pey AL, Ere?o-Orbea J, Mart?nez-Chantar ML, Khalaf-Nazzal R, Claverie-Martin F, M?ller D, Tremblay ML, Mart?nez-Cruz LA
The Journal of biological chemistry292(3)786-801(2017 01)

Role of phosphatase of regenerating liver 1 (PRL1) in spermatogenesis.
Bai Y, Zhou HM, Zhang L, Dong Y, Zeng Q, Shou W, Zhang ZY
Scientific reports634211(2016 Sep)

Protein tyrosine phosphatase of liver regeneration-1 is required for normal timing of cell cycle progression during liver regeneration.
Jiao Y, Ye DZ, Li Z, Teta-Bissett M, Peng Y, Taub R, Greenbaum LE, Kaestner KH
American journal of physiology. Gastrointestinal and liver physiology308(2)G85-91(2015 Jan)

Targeted deletion of the metastasis-associated phosphatase Ptp4a3 (PRL-3) suppresses murine colon cancer.
Zimmerman MW, Homanics GE, Lazo JS
PloS one8(3)e58300(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

data shed new light on the structural basis underlying the interaction between PRL phosphatases and CNNM transporters and provides a hypothesis about the molecular mechanism by which PRL-1, upon binding to CNNM2, might increase the intracellular concentration of Mg(2+) thereby contributing to tumor progression and metastasis.
Title: Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.

Prl-1 is required for proper timing of liver regeneration after partial hepatectomy
Title: Protein tyrosine phosphatase of liver regeneration-1 is required for normal timing of cell cycle progression during liver regeneration.

PRL-1 binding to p115 RhoGAP provides a coordinated mechanism underlying ERK1/2 and RhoA activation
Title: PRL-1 protein promotes ERK1/2 and RhoA protein activation through a non-canonical interaction with the Src homology 3 domain of p115 Rho GTPase-activating protein.

In cones and cone-derived cultured cells both Prl-1 activity and Prl-1 gene expression are modulated under oxidative stress.
Title: Oxidative stress-induced expression and modulation of Phosphatase of Regenerating Liver-1 (PRL-1) in mammalian retina.

The following Ptp4a1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ptp4a1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu20731	NM_011200.2 Latest version!	Mus musculus protein tyrosine phosphatase 4a1 (Ptp4a1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu20731	XM_006495798.4 Latest version!	Mus musculus protein tyrosine phosphatase 4a1 (Ptp4a1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu20731	XM_006495799.3 Latest version!	Mus musculus protein tyrosine phosphatase 4a1 (Ptp4a1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu20731	XM_006495798.3	Mus musculus protein tyrosine phosphatase 4a1 (Ptp4a1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu20731	XM_006495799.2	Mus musculus protein tyrosine phosphatase 4a1 (Ptp4a1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ptp4a1 ( NM_011200.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035330.1 Mus musculus protein tyrosine phosphatase 4a1 (Ptp4a1), mRNA.

Price & Availability↑

CloneID	OMu20731
Clone ID Related Accession (Same CDS sequence)	XM_006495799.2 , XM_006495798.4 , NM_011200.2 , XM_006495798.3 , XM_006495799.3
Accession Version	NM_011200.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 522bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	protein tyrosine phosphatase type IVA 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK148288.1, CA315780.1, AK151533.1, AK078120.1 and AI451864.1. On Nov 8, 2006 this sequence version replaced NM_011200.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC031734.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTCGAA TGAACCGCCC TGCTCCTGTG GAAGTCACAT ACAAGAACAT GCGATTTCTT 
ATTACACACA ATCCAACCAA TGCGACCTTA AACAAATTTA TAGAGGAACT TAAGAAGTAT 
GGAGTTACCA CAATAGTAAG AGTATGTGAA GCAACTTACG ACACTACTCT TGTGGAGAAA 
GAAGGCATTC ATGTTCTTGA CTGGCCTTTT GATGATGGTG CACCACCATC CAACCAGATT 
GTCGATGACT GGCTAAGTCT TGTGAAGATT AAGTTTCGTG AAGAACCTGG TTGCTGTATT 
GCTGTCCATT GTGTCGCAGG CCTTGGCAGA GCTCCGGTGC TTGTTGCCCT AGCATTAATT 
GAAGGTGGAA TGAAATATGA AGATGCAGTA CAATTCATAA GACAAAAGCG GCGTGGAGCT 
TTTAACAGCA AGCAACTTTT GTATCTGGAG AAGTACCGTC CGAAAATGCG GCTCCGCTTC 
AAGGATTCCA ATGGTCATAG AAACAACTGT TGTATTCAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035330.1
CDS	705..1226
Translation	MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ

Target ORF information:

RefSeq Version	NM_011200.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein tyrosine phosphatase 4a1 (Ptp4a1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011200.2

ORF Insert Sequence:

ATGGCTCGAA TGAACCGCCC TGCTCCTGTG GAAGTCACAT ACAAGAACAT GCGATTTCTT 
ATTACACACA ATCCAACCAA TGCGACCTTA AACAAATTTA TAGAGGAACT TAAGAAGTAT 
GGAGTTACCA CAATAGTAAG AGTATGTGAA GCAACTTACG ACACTACTCT TGTGGAGAAA 
GAAGGCATTC ATGTTCTTGA CTGGCCTTTT GATGATGGTG CACCACCATC CAACCAGATT 
GTCGATGACT GGCTAAGTCT TGTGAAGATT AAGTTTCGTG AAGAACCTGG TTGCTGTATT 
GCTGTCCATT GTGTCGCAGG CCTTGGCAGA GCTCCGGTGC TTGTTGCCCT AGCATTAATT 
GAAGGTGGAA TGAAATATGA AGATGCAGTA CAATTCATAA GACAAAAGCG GCGTGGAGCT 
TTTAACAGCA AGCAACTTTT GTATCTGGAG AAGTACCGTC CGAAAATGCG GCTCCGCTTC 
AAGGATTCCA ATGGTCATAG AAACAACTGT TGTATTCAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ptp4a1 ( XM_006495799.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006495862.1 Mus musculus protein tyrosine phosphatase 4a1 (Ptp4a1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu20731
Clone ID Related Accession (Same CDS sequence)	XM_006495799.2 , XM_006495798.4 , NM_011200.2 , XM_006495798.3 , XM_006495799.3
Accession Version	XM_006495799.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 522bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	protein tyrosine phosphatase type IVA 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006495799.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCGAA TGAACCGCCC TGCTCCTGTG GAAGTCACAT ACAAGAACAT GCGATTTCTT 
ATTACACACA ATCCAACCAA TGCGACCTTA AACAAATTTA TAGAGGAACT TAAGAAGTAT 
GGAGTTACCA CAATAGTAAG AGTATGTGAA GCAACTTACG ACACTACTCT TGTGGAGAAA 
GAAGGCATTC ATGTTCTTGA CTGGCCTTTT GATGATGGTG CACCACCATC CAACCAGATT 
GTCGATGACT GGCTAAGTCT TGTGAAGATT AAGTTTCGTG AAGAACCTGG TTGCTGTATT 
GCTGTCCATT GTGTCGCAGG CCTTGGCAGA GCTCCGGTGC TTGTTGCCCT AGCATTAATT 
GAAGGTGGAA TGAAATATGA AGATGCAGTA CAATTCATAA GACAAAAGCG GCGTGGAGCT 
TTTAACAGCA AGCAACTTTT GTATCTGGAG AAGTACCGTC CGAAAATGCG GCTCCGCTTC 
AAGGATTCCA ATGGTCATAG AAACAACTGT TGTATTCAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006495862.1
CDS	834..1355
Translation	MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ

Target ORF information:

RefSeq Version	XM_006495799.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein tyrosine phosphatase 4a1 (Ptp4a1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006495799.2

ORF Insert Sequence:

ATGGCTCGAA TGAACCGCCC TGCTCCTGTG GAAGTCACAT ACAAGAACAT GCGATTTCTT 
ATTACACACA ATCCAACCAA TGCGACCTTA AACAAATTTA TAGAGGAACT TAAGAAGTAT 
GGAGTTACCA CAATAGTAAG AGTATGTGAA GCAACTTACG ACACTACTCT TGTGGAGAAA 
GAAGGCATTC ATGTTCTTGA CTGGCCTTTT GATGATGGTG CACCACCATC CAACCAGATT 
GTCGATGACT GGCTAAGTCT TGTGAAGATT AAGTTTCGTG AAGAACCTGG TTGCTGTATT 
GCTGTCCATT GTGTCGCAGG CCTTGGCAGA GCTCCGGTGC TTGTTGCCCT AGCATTAATT 
GAAGGTGGAA TGAAATATGA AGATGCAGTA CAATTCATAA GACAAAAGCG GCGTGGAGCT 
TTTAACAGCA AGCAACTTTT GTATCTGGAG AAGTACCGTC CGAAAATGCG GCTCCGCTTC 
AAGGATTCCA ATGGTCATAG AAACAACTGT TGTATTCAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ptp4a1 ( XM_006495798.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006495861.1 Mus musculus protein tyrosine phosphatase 4a1 (Ptp4a1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu20731
Clone ID Related Accession (Same CDS sequence)	XM_006495799.2 , XM_006495798.4 , NM_011200.2 , XM_006495798.3 , XM_006495799.3
Accession Version	XM_006495798.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 522bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	protein tyrosine phosphatase type IVA 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006495798.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCGAA TGAACCGCCC TGCTCCTGTG GAAGTCACAT ACAAGAACAT GCGATTTCTT 
ATTACACACA ATCCAACCAA TGCGACCTTA AACAAATTTA TAGAGGAACT TAAGAAGTAT 
GGAGTTACCA CAATAGTAAG AGTATGTGAA GCAACTTACG ACACTACTCT TGTGGAGAAA 
GAAGGCATTC ATGTTCTTGA CTGGCCTTTT GATGATGGTG CACCACCATC CAACCAGATT 
GTCGATGACT GGCTAAGTCT TGTGAAGATT AAGTTTCGTG AAGAACCTGG TTGCTGTATT 
GCTGTCCATT GTGTCGCAGG CCTTGGCAGA GCTCCGGTGC TTGTTGCCCT AGCATTAATT 
GAAGGTGGAA TGAAATATGA AGATGCAGTA CAATTCATAA GACAAAAGCG GCGTGGAGCT 
TTTAACAGCA AGCAACTTTT GTATCTGGAG AAGTACCGTC CGAAAATGCG GCTCCGCTTC 
AAGGATTCCA ATGGTCATAG AAACAACTGT TGTATTCAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006495861.1
CDS	1128..1649
Translation	MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ

Target ORF information:

RefSeq Version	XM_006495798.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein tyrosine phosphatase 4a1 (Ptp4a1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006495798.3

ORF Insert Sequence:

ATGGCTCGAA TGAACCGCCC TGCTCCTGTG GAAGTCACAT ACAAGAACAT GCGATTTCTT 
ATTACACACA ATCCAACCAA TGCGACCTTA AACAAATTTA TAGAGGAACT TAAGAAGTAT 
GGAGTTACCA CAATAGTAAG AGTATGTGAA GCAACTTACG ACACTACTCT TGTGGAGAAA 
GAAGGCATTC ATGTTCTTGA CTGGCCTTTT GATGATGGTG CACCACCATC CAACCAGATT 
GTCGATGACT GGCTAAGTCT TGTGAAGATT AAGTTTCGTG AAGAACCTGG TTGCTGTATT 
GCTGTCCATT GTGTCGCAGG CCTTGGCAGA GCTCCGGTGC TTGTTGCCCT AGCATTAATT 
GAAGGTGGAA TGAAATATGA AGATGCAGTA CAATTCATAA GACAAAAGCG GCGTGGAGCT 
TTTAACAGCA AGCAACTTTT GTATCTGGAG AAGTACCGTC CGAAAATGCG GCTCCGCTTC 
AAGGATTCCA ATGGTCATAG AAACAACTGT TGTATTCAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ptp4a1 ( XM_006495798.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006495861.1 Mus musculus protein tyrosine phosphatase 4a1 (Ptp4a1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu20731
Clone ID Related Accession (Same CDS sequence)	XM_006495799.2 , XM_006495798.4 , NM_011200.2 , XM_006495798.3 , XM_006495799.3
Accession Version	XM_006495798.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 522bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	protein tyrosine phosphatase type IVA 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006495798.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCGAA TGAACCGCCC TGCTCCTGTG GAAGTCACAT ACAAGAACAT GCGATTTCTT 
ATTACACACA ATCCAACCAA TGCGACCTTA AACAAATTTA TAGAGGAACT TAAGAAGTAT 
GGAGTTACCA CAATAGTAAG AGTATGTGAA GCAACTTACG ACACTACTCT TGTGGAGAAA 
GAAGGCATTC ATGTTCTTGA CTGGCCTTTT GATGATGGTG CACCACCATC CAACCAGATT 
GTCGATGACT GGCTAAGTCT TGTGAAGATT AAGTTTCGTG AAGAACCTGG TTGCTGTATT 
GCTGTCCATT GTGTCGCAGG CCTTGGCAGA GCTCCGGTGC TTGTTGCCCT AGCATTAATT 
GAAGGTGGAA TGAAATATGA AGATGCAGTA CAATTCATAA GACAAAAGCG GCGTGGAGCT 
TTTAACAGCA AGCAACTTTT GTATCTGGAG AAGTACCGTC CGAAAATGCG GCTCCGCTTC 
AAGGATTCCA ATGGTCATAG AAACAACTGT TGTATTCAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006495861.1
CDS	824..1345
Translation	MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ

Target ORF information:

RefSeq Version	XM_006495798.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein tyrosine phosphatase 4a1 (Ptp4a1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006495798.4

ORF Insert Sequence:

ATGGCTCGAA TGAACCGCCC TGCTCCTGTG GAAGTCACAT ACAAGAACAT GCGATTTCTT 
ATTACACACA ATCCAACCAA TGCGACCTTA AACAAATTTA TAGAGGAACT TAAGAAGTAT 
GGAGTTACCA CAATAGTAAG AGTATGTGAA GCAACTTACG ACACTACTCT TGTGGAGAAA 
GAAGGCATTC ATGTTCTTGA CTGGCCTTTT GATGATGGTG CACCACCATC CAACCAGATT 
GTCGATGACT GGCTAAGTCT TGTGAAGATT AAGTTTCGTG AAGAACCTGG TTGCTGTATT 
GCTGTCCATT GTGTCGCAGG CCTTGGCAGA GCTCCGGTGC TTGTTGCCCT AGCATTAATT 
GAAGGTGGAA TGAAATATGA AGATGCAGTA CAATTCATAA GACAAAAGCG GCGTGGAGCT 
TTTAACAGCA AGCAACTTTT GTATCTGGAG AAGTACCGTC CGAAAATGCG GCTCCGCTTC 
AAGGATTCCA ATGGTCATAG AAACAACTGT TGTATTCAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ptp4a1 ( XM_006495799.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006495862.1 Mus musculus protein tyrosine phosphatase 4a1 (Ptp4a1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu20731
Clone ID Related Accession (Same CDS sequence)	XM_006495799.2 , XM_006495798.4 , NM_011200.2 , XM_006495798.3 , XM_006495799.3
Accession Version	XM_006495799.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 522bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	protein tyrosine phosphatase type IVA 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006495799.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCGAA TGAACCGCCC TGCTCCTGTG GAAGTCACAT ACAAGAACAT GCGATTTCTT 
ATTACACACA ATCCAACCAA TGCGACCTTA AACAAATTTA TAGAGGAACT TAAGAAGTAT 
GGAGTTACCA CAATAGTAAG AGTATGTGAA GCAACTTACG ACACTACTCT TGTGGAGAAA 
GAAGGCATTC ATGTTCTTGA CTGGCCTTTT GATGATGGTG CACCACCATC CAACCAGATT 
GTCGATGACT GGCTAAGTCT TGTGAAGATT AAGTTTCGTG AAGAACCTGG TTGCTGTATT 
GCTGTCCATT GTGTCGCAGG CCTTGGCAGA GCTCCGGTGC TTGTTGCCCT AGCATTAATT 
GAAGGTGGAA TGAAATATGA AGATGCAGTA CAATTCATAA GACAAAAGCG GCGTGGAGCT 
TTTAACAGCA AGCAACTTTT GTATCTGGAG AAGTACCGTC CGAAAATGCG GCTCCGCTTC 
AAGGATTCCA ATGGTCATAG AAACAACTGT TGTATTCAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006495862.1
CDS	856..1377
Translation	MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ

Target ORF information:

RefSeq Version	XM_006495799.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein tyrosine phosphatase 4a1 (Ptp4a1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006495799.3

ORF Insert Sequence:

ATGGCTCGAA TGAACCGCCC TGCTCCTGTG GAAGTCACAT ACAAGAACAT GCGATTTCTT 
ATTACACACA ATCCAACCAA TGCGACCTTA AACAAATTTA TAGAGGAACT TAAGAAGTAT 
GGAGTTACCA CAATAGTAAG AGTATGTGAA GCAACTTACG ACACTACTCT TGTGGAGAAA 
GAAGGCATTC ATGTTCTTGA CTGGCCTTTT GATGATGGTG CACCACCATC CAACCAGATT 
GTCGATGACT GGCTAAGTCT TGTGAAGATT AAGTTTCGTG AAGAACCTGG TTGCTGTATT 
GCTGTCCATT GTGTCGCAGG CCTTGGCAGA GCTCCGGTGC TTGTTGCCCT AGCATTAATT 
GAAGGTGGAA TGAAATATGA AGATGCAGTA CAATTCATAA GACAAAAGCG GCGTGGAGCT 
TTTAACAGCA AGCAACTTTT GTATCTGGAG AAGTACCGTC CGAAAATGCG GCTCCGCTTC 
AAGGATTCCA ATGGTCATAG AAACAACTGT TGTATTCAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

PTP4A1 promotes TGF? signaling and fibrosis in systemic sclerosis.
Nature communications8(1)1060(2017 Oct)
Sacchetti C,Bai Y,Stanford SM,Di Benedetto P,Cipriani P,Santelli E,Piera-Velazquez S,Chernitskiy V,Kiosses WB,Ceponis A,Kaestner KH,Boin F,Jimenez SA,Giacomelli R,Zhang ZY,Bottini N

Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.
The Journal of biological chemistry292(3)786-801(2017 01)
Gim?nez-Mascarell P,Oyenarte I,Hardy S,Breiderhoff T,Stuiver M,Kostantin E,Diercks T,Pey AL,Ere?o-Orbea J,Mart?nez-Chantar ML,Khalaf-Nazzal R,Claverie-Martin F,M?ller D,Tremblay ML,Mart?nez-Cruz LA

Role of phosphatase of regenerating liver 1 (PRL1) in spermatogenesis.
Scientific reports634211(2016 Sep)
Bai Y,Zhou HM,Zhang L,Dong Y,Zeng Q,Shou W,Zhang ZY

Protein tyrosine phosphatase of liver regeneration-1 is required for normal timing of cell cycle progression during liver regeneration.
American journal of physiology. Gastrointestinal and liver physiology308(2)G85-91(2015 Jan)
Jiao Y,Ye DZ,Li Z,Teta-Bissett M,Peng Y,Taub R,Greenbaum LE,Kaestner KH

Targeted deletion of the metastasis-associated phosphatase Ptp4a3 (PRL-3) suppresses murine colon cancer.
PloS one8(3)e58300(2013)
Zimmerman MW,Homanics GE,Lazo JS

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Ptp4a1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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オンラインフォーム