gRNAs
The following Mtx1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mtx1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu13545 | |
| Clone ID Related Accession (Same CDS sequence) | NM_013604.2 | |
| Accession Version | NM_013604.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1386bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-02-21 | |
| Organism | Mus musculus(house mouse) | |
| Product | metaxin-1 isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY086463.1, AC161600.6, BB662550.1, AK163982.1 and AI448305.1. On Jun 25, 2009 this sequence version replaced NM_013604.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. CCDS Note: The coding region has been updated to extend the N-terminus to one that is supported by available conservation data. The use of an alternative upstream start codon would result in a protein that is 144 aa longer at the N-terminal and includes a predicted mitochondrial transit peptide (aa 1-92; by MITOPROT). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK086135.1, AK165923.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164140 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGCGGCTCG GGGGACCCCC CCGCGGCGTC CGCTCAGGGC TGAGACCTGA GAGGGCCCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_038632.2 |
| CDS | 11..1396 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_013604.2 |
1 | ATGCGGCTCG GGGGACCCCC CCGCGGCGTC CGCTCAGGGC TGAGACCTGA GAGGGCCCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu13646 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001161824.1 | |
| Accession Version | NM_001161824.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1383bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-02-22 | |
| Organism | Mus musculus(house mouse) | |
| Product | metaxin-1 isoform 2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC161600.6. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the coding region compared to variant 1. This results in a shorter protein (isoform 2) compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BI409506.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164140 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGCGGCTCG GGGGACCCCC CCGCGGCGTC CGCTCAGGGC TGAGACCTGA GAGGGCCCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001155296.1 |
| CDS | 11..1393 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001161824.1 |
1 | ATGCGGCTCG GGGGACCCCC CCGCGGCGTC CGCTCAGGGC TGAGACCTGA GAGGGCCCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu31684 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001357367.1 , XM_006501104.3 | |
| Accession Version | NM_001357367.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1500bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-09-29 | |
| Organism | Mus musculus(house mouse) | |
| Product | metaxin-1 isoform 3 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC161600.6 and AK159316.1. On Oct 26, 2017 this sequence version replaced XM_006501104.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK159316.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164140 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGCGGCTCG GGGGACCCCC CCGCGGCGTC CGCTCAGGGC TGAGACCTGA GAGGGCCCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001344296.1 |
| CDS | 11..1510 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001357367.1 |
1 | ATGCGGCTCG GGGGACCCCC CCGCGGCGTC CGCTCAGGGC TGAGACCTGA GAGGGCCCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu31684 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001357367.1 , XM_006501104.3 | |
| Accession Version | XM_006501104.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1500bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-06-21 | |
| Organism | Mus musculus(House mouse) | |
| Product | metaxin-1 isoform X1 | |
| Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000069.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006501104.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGCGGCTCG GGGGACCCCC CCGCGGCGTC CGCTCAGGGC TGAGACCTGA GAGGGCCCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006501167.1 |
| CDS | 17..1516 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006501104.3 |
1 | ATGCGGCTCG GGGGACCCCC CCGCGGCGTC CGCTCAGGGC TGAGACCTGA GAGGGCCCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu84813 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001161824.2 | |
| Accession Version | NM_001161824.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 951bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2020-01-03 | |
| Organism | Mus musculus(house mouse) | |
| Product | metaxin-1 isoform 2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC161600.6. On May 31, 2019 this sequence version replaced NM_001161824.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BI409506.1, SRR7345562.2000627.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164140 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGCGGCGC CCATGGAGCT GTTCTGCTGG TCAGGGGGCT GGGGATTGCC GTCGGTGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001155296.2 |
| CDS | 15..965 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001161824.2 |
1 | ATGGCGGCGC CCATGGAGCT GTTCTGCTGG TCAGGGGGCT GGGGATTGCC GTCGGTGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu84815 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001357367.2 | |
| Accession Version | NM_001357367.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1068bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2020-01-03 | |
| Organism | Mus musculus(house mouse) | |
| Product | metaxin-1 isoform 3 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC161600.6. On Jun 1, 2019 this sequence version replaced NM_001357367.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK159316.1, SRR7345562.2044768.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164140 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGCGGCGC CCATGGAGCT GTTCTGCTGG TCAGGGGGCT GGGGATTGCC GTCGGTGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001344296.2 |
| CDS | 15..1082 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001357367.2 |
1 | ATGGCGGCGC CCATGGAGCT GTTCTGCTGG TCAGGGGGCT GGGGATTGCC GTCGGTGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu84816 | |
| Clone ID Related Accession (Same CDS sequence) | NM_013604.3 | |
| Accession Version | NM_013604.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 954bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2020-01-03 | |
| Organism | Mus musculus(house mouse) | |
| Product | metaxin-1 isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC161600.6. On Jun 1, 2019 this sequence version replaced NM_013604.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. CCDS Note: The coding region has been updated to extend the N-terminus to one that is supported by available conservation data. The use of an alternative upstream start codon would result in a protein that is 144 aa longer at the N-terminal and includes a predicted mitochondrial transit peptide (aa 1-92; by MITOPROT). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK165923.1, AK165547.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164140 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGCGGCGC CCATGGAGCT GTTCTGCTGG TCAGGGGGCT GGGGATTGCC GTCGGTGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_038632.3 |
| CDS | 15..968 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_013604.3 |
1 | ATGGCGGCGC CCATGGAGCT GTTCTGCTGG TCAGGGGGCT GGGGATTGCC GTCGGTGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Metaxin deficiency alters mitochondrial membrane permeability and leads to resistance to TNF-induced cell killing. |
Targeting and insertion of the cholesterol-binding translocator protein into the outer mitochondrial membrane. |
The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. |
A germline-specific class of small RNAs binds mammalian Piwi proteins. |
Mice with type 2 and 3 Gaucher disease point mutations generated by a single insertion mutagenesis procedure. |
