Cd209a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cd209a
Entrez Gene ID	170786
Full Name	CD209a antigen
Synonyms	CD209,CDSIGN,CIRE,DC-SIGN,DC-SIGN1,Dcsign,SIGN-R1,SIGNR5
General protein information	Preferred Names CD209a antigen Names CD209 antigen-like protein A dendritic cell-specific ICAM-3-grabbing non-integrin
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8\|8 A1.1

mRNA and Protein(s)

mRNA	Protein	Name
NM_133238.5	NP_573501.1	CD209 antigen-like protein A

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	zgc:174904	NP_001170922.1
Homo sapiens (human)	CLEC4M	NP_001138381.1
Pan troglodytes (chimpanzee)	LOC100611969	XP_003953385.1
Mus musculus (house mouse)	Cd209a	NP_573501.1
Rattus norvegicus (Norway rat)	Cd209a	NP_001099374.1

Gene Ontology
Bibliography

Related articles in PubMed

LECT2 drives haematopoietic stem cell expansion and mobilization via regulating the macrophages and osteolineage cells.
Lu XJ, Chen Q, Rong YJ, Yang GJ, Li CH, Xu NY, Yu CH, Wang HY, Zhang S, Shi YH, Chen J
Nature communications712719(2016 Sep)

TLR4 and DC-SIGN receptors recognized Mycobacterium scrofulaceum promoting semi-activated phenotype on bone marrow dendritic cells.
Cruz-Aguilar M, Castillo-Rodal AI, Schcolnik-Cabrera A, Bonifaz LC, Molina G, L?pez-Vidal Y
Tuberculosis (Edinburgh, Scotland)9931-40(2016 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

M. scrofulaceum induces a semimature DC phenotype that is characterized by PD-L2 over-expression and elevated synthesis of IL-10, most likely through TLR4 and Raf-1 signaling pathway-dependent DC-SIGN stimulation.
Title: TLR4 and DC-SIGN receptors recognized Mycobacterium scrofulaceum promoting semi-activated phenotype on bone marrow dendritic cells.

results suggested that podocytes in lupus nephritis can exert dendritic cell-like function through their expression of DC-SIGN, which may be involved in immune and inflammatory responses of renal tissues
Title: DC-SIGN expression on podocytes and its role in inflammatory immune response of lupus nephritis.

results indicate that SIGN-R1 and complement factors play an important role in the systemic clearance of radiation-induced apoptotic innate immune cells to maintain tissue homeostasis after gamma-irradiation
Title: SIGN-R1 and complement factors are involved in the systemic clearance of radiation-induced apoptotic cells in whole-body irradiated mice.

Data suggest that serum amyloid P (SAP) activates CD209 DC-SIGN to regulate the innate immune system differently from C-reactive protein (CRP), and that DC-SIGN is a target for antifibrotics.
Title: DC-SIGN activation mediates the differential effects of SAP and CRP on the innate immune system and inhibits fibrosis in mice.

Intestinal enterocytes regulate tissue-associated immune compartments under the control of DC-SIGN in inflammatory bowel disease.
Title: Enterocyte dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin expression in inflammatory bowel disease.

The following Cd209a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cd209a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu09969	NM_133238.5 Latest version!	Mus musculus CD209a antigen (Cd209a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cd209a ( NM_133238.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_573501.1 Mus musculus CD209a antigen (Cd209a), mRNA.

Price & Availability↑

CloneID	OMu09969
Clone ID Related Accession (Same CDS sequence)	NM_133238.5
Accession Version	NM_133238.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 717bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-23
Organism	Mus musculus(house mouse)
Product	CD209 antigen-like protein A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY049062.1. On Apr 28, 2009 this sequence version replaced NM_133238.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY049062.1, AK054139.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164134 [ECO:0000348] ##Evidence-Data-END##

ATGAGTGATT CTAAGGAAAT GGGGAAGAGG CAGCTTCGCC CTCTGGATGA GGAACTGCTG 
ACATCCAGCC ACACCAGGCA CTCCATCAAA GGCTTTGGCT TCCAAACAAA TTCTGGATTC 
AGTAGCTTCA CAGGGTGCCT GGTCCACAGT CAAGTCCCCT TGGCACTGCA GGTGCTCTTC 
CTAGCTGTTT GTTCTGTGCT GCTGGTTGTC ATCCTTGTCA AAGTCTACAA AATACCCAGT 
TCTCAGGAAG AAAACAATCA GATGAATGTC TACCAAGAAC TGACCCAGTT GAAGGCTGGC 
GTAGATCGAC TGTGCCGCTC CTGCCCCTGG GACTGGACGC ACTTCCAAGG AAGCTGTTAC 
TTCTTCTCTG TGGCCCAGAA GTCCTGGAAT GATTCTGCCA CTGCCTGCCA CAATGTGGGG 
GCTCAACTTG TGGTCATCAA GAGTGATGAA GAGCAGAACT TTCTACAACA AACTTCTAAG 
AAGAGAGGCT ACACTTGGAT GGGGCTCATT GACATGAGCA AGGAGTCTAC ATGGTACTGG 
GTAGATGGTT CACCTCTGAC TCTCAGTTTC ATGAAGTATT GGAGTAAAGG AGAACCTAAC 
AACCTGGGAG AGGAAGACTG TGCAGAGTTC AGAGATGACG GCTGGAATGA CACCAAATGT 
ACTAACAAGA AATTCTGGAT CTGCAAAAAG CTTTCAACTT CCTGCCCTAG CAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_573501.1
CDS	79..795
Translation	MSDSKEMGKRQLRPLDEELLTSSHTRHSIKGFGFQTNSGFSSFTGCLVHSQVPLALQVLFLAVCSVLLVVILVKVYKIPSSQEENNQMNVYQELTQLKAGVDRLCRSCPWDWTHFQGSCYFFSVAQKSWNDSATACHNVGAQLVVIKSDEEQNFLQQTSKKRGYTWMGLIDMSKESTWYWVDGSPLTLSFMKYWSKGEPNNLGEEDCAEFRDDGWNDTKCTNKKFWICKKLSTSCPSK

Target ORF information:

RefSeq Version	NM_133238.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus CD209a antigen (Cd209a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133238.5

ORF Insert Sequence:

ATGAGTGATT CTAAGGAAAT GGGGAAGAGG CAGCTTCGCC CTCTGGATGA GGAACTGCTG 
ACATCCAGCC ACACCAGGCA CTCCATCAAA GGCTTTGGCT TCCAAACAAA TTCTGGATTC 
AGTAGCTTCA CAGGGTGCCT GGTCCACAGT CAAGTCCCCT TGGCACTGCA GGTGCTCTTC 
CTAGCTGTTT GTTCTGTGCT GCTGGTTGTC ATCCTTGTCA AAGTCTACAA AATACCCAGT 
TCTCAGGAAG AAAACAATCA GATGAATGTC TACCAAGAAC TGACCCAGTT GAAGGCTGGC 
GTAGATCGAC TGTGCCGCTC CTGCCCCTGG GACTGGACGC ACTTCCAAGG AAGCTGTTAC 
TTCTTCTCTG TGGCCCAGAA GTCCTGGAAT GATTCTGCCA CTGCCTGCCA CAATGTGGGG 
GCTCAACTTG TGGTCATCAA GAGTGATGAA GAGCAGAACT TTCTACAACA AACTTCTAAG 
AAGAGAGGCT ACACTTGGAT GGGGCTCATT GACATGAGCA AGGAGTCTAC ATGGTACTGG 
GTAGATGGTT CACCTCTGAC TCTCAGTTTC ATGAAGTATT GGAGTAAAGG AGAACCTAAC 
AACCTGGGAG AGGAAGACTG TGCAGAGTTC AGAGATGACG GCTGGAATGA CACCAAATGT 
ACTAACAAGA AATTCTGGAT CTGCAAAAAG CTTTCAACTT CCTGCCCTAG CAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

LECT2 drives haematopoietic stem cell expansion and mobilization via regulating the macrophages and osteolineage cells.
Nature communications712719(2016 Sep)
Lu XJ,Chen Q,Rong YJ,Yang GJ,Li CH,Xu NY,Yu CH,Wang HY,Zhang S,Shi YH,Chen J

TLR4 and DC-SIGN receptors recognized Mycobacterium scrofulaceum promoting semi-activated phenotype on bone marrow dendritic cells.
Tuberculosis (Edinburgh, Scotland)9931-40(2016 Jul)
Cruz-Aguilar M,Castillo-Rodal AI,Schcolnik-Cabrera A,Bonifaz LC,Molina G,L?pez-Vidal Y

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Cd209a cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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