Lst1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lst1
Entrez Gene ID	16988
Full Name	leukocyte specific transcript 1
Synonyms	B144
General protein information	Preferred Names leukocyte specific transcript 1 Names leukocyte-specific transcript 1 protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17 B1\|17 18.59 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_010734.2	NP_034864.2	leukocyte-specific transcript 1 protein

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Lst1 deficiency has a minor impact on course and outcome of the host response to influenza A H1N1 infections in mice.
Leist SR, Kollmus H, Hatesuer B, Lambertz RL, Schughart K
Virology journal1317(2016 Jan)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.
Abdallah BM, Ditzel N, Mahmood A, Isa A, Traustadottir GA, Schilling AF, Ruiz-Hidalgo MJ, Laborda J, Amling M, Kassem M
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research26(7)1457-71(2011 Jul)

A collection of cDNAs enriched in upper cortical layers of the embryonic mouse brain.
Garc?a-Frigola C, Burgaya F, Calbet M, L?pez-Dom?nech G, de Lecea L, Soriano E
Brain research. Molecular brain research122(2)133-50(2004 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The absence of Lst1 leads to a slightly more susceptible phenotype. However, deletion of Lst1 in DBA/2 J mice alone does not explain the high susceptibility of this strain to PR8M influenza infections.
Title: Lst1 deficiency has a minor impact on course and outcome of the host response to influenza A H1N1 infections in mice.

The following Lst1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lst1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu06736	NM_010734.2 Latest version!	Mus musculus leukocyte specific transcript 1 (Lst1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lst1 ( NM_010734.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034864.2 Mus musculus leukocyte specific transcript 1 (Lst1), mRNA.

Price & Availability↑

CloneID	OMu06736
Clone ID Related Accession (Same CDS sequence)	NM_010734.2
Accession Version	NM_010734.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 282bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Mus musculus(house mouse)
Product	leukocyte-specific transcript 1 protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AI182980.1, AI323110.1 and AI482475.1. On Jan 29, 2005 this sequence version replaced NM_010734.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AI182980.1, BC086881.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135, SAMN01164143 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACAATGG GATCTGGTAA CAATTGCACA ACCAATGATT TCCTGCTAAA TGGGAGCCTG 
GGACTGGGAG GGCTCCTCCT CCTGCTTGTC ATCATCCTGT TCATCTGCTT GTGCCGGTTC 
AGTCAGAGAG TGAAGAGACT GGAAAGGAAT GCCCAGGTCT CAGGGCAGGA GCCCCACTAT 
GCATCTCTCC AGCAGCTGCC AGTGTCCAGT AGTGATATCA CAGACATGAA AGAAGACCTC 
AGCACTGACT ATGCCTGCAT CGCCAGGAGC ACACCCACTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034864.2
CDS	51..332
Translation	MTMGSGNNCTTNDFLLNGSLGLGGLLLLLVIILFICLCRFSQRVKRLERNAQVSGQEPHYASLQQLPVSSSDITDMKEDLSTDYACIARSTPT

Target ORF information:

RefSeq Version	NM_010734.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus leukocyte specific transcript 1 (Lst1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010734.2

ORF Insert Sequence:

ATGACAATGG GATCTGGTAA CAATTGCACA ACCAATGATT TCCTGCTAAA TGGGAGCCTG 
GGACTGGGAG GGCTCCTCCT CCTGCTTGTC ATCATCCTGT TCATCTGCTT GTGCCGGTTC 
AGTCAGAGAG TGAAGAGACT GGAAAGGAAT GCCCAGGTCT CAGGGCAGGA GCCCCACTAT 
GCATCTCTCC AGCAGCTGCC AGTGTCCAGT AGTGATATCA CAGACATGAA AGAAGACCTC 
AGCACTGACT ATGCCTGCAT CGCCAGGAGC ACACCCACTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Lst1 deficiency has a minor impact on course and outcome of the host response to influenza A H1N1 infections in mice.
Virology journal1317(2016 Jan)
Leist SR,Kollmus H,Hatesuer B,Lambertz RL,Schughart K

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research26(7)1457-71(2011 Jul)
Abdallah BM,Ditzel N,Mahmood A,Isa A,Traustadottir GA,Schilling AF,Ruiz-Hidalgo MJ,Laborda J,Amling M,Kassem M

A collection of cDNAs enriched in upper cortical layers of the embryonic mouse brain.
Brain research. Molecular brain research122(2)133-50(2004 Mar)
Garc?a-Frigola C,Burgaya F,Calbet M,L?pez-Dom?nech G,de Lecea L,Soriano E

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Lst1 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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