Itih4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Itih4
Entrez Gene ID	16427
Full Name	inter alpha-trypsin inhibitor, heavy chain 4
Synonyms	ITI-HC4,Itih-4,PK-120
General protein information	Preferred Names inter alpha-trypsin inhibitor, heavy chain 4 Names inter alpha-trypsin inhibitor, heavy chain 4 ITI heavy chain H4 inter-alpha-inhibitor heavy chain 4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 14 Map Location: 14 B\|14 19.09 cM
Summary	This gene encodes a member of the inter-alpha trypsin inhibitor (IaI) family of plasma serine protease inhibitors with diverse functions as anti-apoptotic and matrix stabilizing molecules during development. This gene is predominantly expressed in the liver and the encoded protein was found to be a plasma kallikrein-sensitive glycoprotein. This gene is located in a cluster of related inter alpha trypsin inhibitor genes on chromosome 14. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001289632.1	NP_001276561.1	inter alpha-trypsin inhibitor, heavy chain 4 isoform 3 precursor
NM_001159299.2	NP_001152771.1	inter alpha-trypsin inhibitor, heavy chain 4 isoform 2 precursor
NM_001289633.1	NP_001276562.1	inter alpha-trypsin inhibitor, heavy chain 4 isoform 4 precursor
NM_018746.4	NP_061216.2	inter alpha-trypsin inhibitor, heavy chain 4 isoform 1 precursor

Pathways from BioSystems

Homologies

	ITIH4	XP_002802831.1
Canis lupus familiaris (dog)	ITIH4	XP_848765.3
Rattus norvegicus (Norway rat)	Itih4	NP_062242.2
Pan troglodytes (chimpanzee)	ITIH4	XP_001172688.1
Bos taurus (cattle)	ITIH4	NP_001015590.2
Homo sapiens (human)	ITIH4	NP_001159921.1
Mus musculus (house mouse)	Itih4	NP_061216.2
Danio rerio (zebrafish)	zgc:112265	NP_001020335.1
Xenopus tropicalis (tropical clawed frog)	LOC100487172	XP_002941978.2

Gene Ontology
Bibliography

Related articles in PubMed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.
Naba A, Clauser KR, Mani DR, Carr SA, Hynes RO
Scientific reports740495(2017 Jan)

Conformational changes in inter-?-trypsin inhibitor heavy chain 4 activate its tumor-specific activity in mice with B16 melanoma.
Kormosh NG, Davidova TV, Kopyltsov VN, Serebryakova MV, Kabieva AO, Voyushin KE, Sitdikova SM, Amandzholov BS, Kiselevskii MV, Donenko FV
Molecular medicine reports12(3)4483-93(2015 Sep)

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.
Naba A, Clauser KR, Hoersch S, Liu H, Carr SA, Hynes RO
Molecular & cellular proteomics : MCP11(4)M111.014647(2012 Apr)

Progenitor/stem cells give rise to liver cancer due to aberrant TGF-beta and IL-6 signaling.
Tang Y, Kitisin K, Jogunoori W, Li C, Deng CX, Mueller SC, Ressom HW, Rashid A, He AR, Mendelson JS, Jessup JM, Shetty K, Zasloff M, Mishra B, Reddy EP, Johnson L, Mishra L
Proceedings of the National Academy of Sciences of the United States of America105(7)2445-50(2008 Feb)

BIP co-chaperone MTJ1/ERDJ1 interacts with inter-alpha-trypsin inhibitor heavy chain 4.
Kroczynska B, King-Simmons L, Alloza L, Alava MA, Elguindi EC, Blond SY
Biochemical and biophysical research communications338(3)1467-77(2005 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Tumor-free mice and mice with B16 melanoma have differential proteolytic fragments of serum ITIH4.
Title: Conformational changes in inter-?-trypsin inhibitor heavy chain 4 activate its tumor-specific activity in mice with B16 melanoma.

role in liver development and regeneration
Title: Itih-4, a serine protease inhibitor regulated in interleukin-6-dependent liver formation: role in liver development and regeneration.

The following Itih4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Itih4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu17354	NM_001289632.1 Latest version!	Mus musculus inter alpha-trypsin inhibitor, heavy chain 4 (Itih4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00
OMu57978	NM_001159299.2 Latest version!	Mus musculus inter alpha-trypsin inhibitor, heavy chain 4 (Itih4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00
OMu57985	NM_018746.4 Latest version!	Mus musculus inter alpha-trypsin inhibitor, heavy chain 4 (Itih4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00
OMu58025	NM_001289633.1 Latest version!	Mus musculus inter alpha-trypsin inhibitor, heavy chain 4 (Itih4), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Itih4 ( NM_001289632.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001276561.1 Mus musculus inter alpha-trypsin inhibitor, heavy chain 4 (Itih4), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu17354
Clone ID Related Accession (Same CDS sequence)	NM_001289632.1
Accession Version	NM_001289632.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2778bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-04
Organism	Mus musculus(house mouse)
Product	inter alpha-trypsin inhibitor, heavy chain 4 isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BY788238.1, AK050270.1 and BB809402.1. On Jan 24, 2014 this sequence version replaced XM_006518589.1. Transcript Variant: This variant (3) lacks an in-frame exon in the 3' coding region, compared to variant 1. This difference results in a shorter protein (isoform 3), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC021459.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGAGCC CTGCCCCTGC CCACATGTGG AACCTTGTGC TGTTCTTGCC TTCACTGTTG 
GCTGTGCTTC CGACCACTAC TGCCGAGAAG AATGGCATCG ATATCTACAG CCTCACGGTG 
GACTCCCGGG TCTCTTCCCG ATTTGCCCAT ACTGTTGTCA CCAGCCGGGT GGTCAACAGA 
GCCGATGCTG TTCAAGAAGC GACCTTCCAA GTAGAGCTAC CCAGGAAAGC CTTCATCACC 
AACTTTTCCA TGATCATCGA TGGCGTGACC TACCCAGGGG TTGTCAAAGA GAAGGCCGAA 
GCCCAGAAAC AATACAGTGC CGCCGTGGGC AGGGGAGAGA GTGCTGGCAT CGTCAAGACC 
ACTGGGAGGC AGACAGAGAA GTTTGAAGTG TCAGTCAACG TGGCCCCTGG TTCCAAGATT 
ACCTTCGAAC TCATATACCA GGAACTGCTC CAAAGGCGAC TGGGAATGTA TGAGCTACTC 
CTCAAAGTGA GGCCTCAGCA GCTGGTGAAG CACCTTCAGA TGGACATCTA CATCTTTGAG 
CCTCAGGGTA TTAGCATCCT GGAGACAGAG AGCACCTTCA TGACCCCGGA GCTGGCAAAT 
GCCCTTACCA CTTCACAGAA CAAGACCAAG GCTCATATCC GGTTCAAGCC GACGCTCTCC 
CAGCAACAGA AGTCTCAGAG TGAGCAGGAC ACGGTGCTGA ATGGGGACTT CATCGTCCGC 
TATGATGTCA ACCGGTCTGA CTCTGGGGGC TCCATTCAGA TTGAGGAAGG CTACTTTGTG 
CACCACTTTG CTCCAGAGAA CCTTCCTACA ATGTCCAAGA ATGTGATCTT TGTCATTGAT 
AAAAGCGGAT CTATGTCAGG CAAGAAAATC CAGCAGACCC GAGAAGCCCT AGTCAAGATC 
TTGAAAGACC TCAGCCCCCA AGACCAGTTC AACCTCATTG AGTTCAGTGG GGAAGCAAAC 
CAATGGAAGC AGTCACTGGT GCAAGCGACA GAAGAGAATT TGAACAAGGC TGTAAACTAT 
GCTTCCAGGA TCCGGGCTCA CGGAGGGACC AACATCAATA ATGCAGTGCT GTTGGCTGTG 
GAGCTGCTGG ACAGAAGCAA CCAAGCTGAG CTACTGCCCT CGAAGAGCGT CTCCCTTATC 
ATCCTGCTCA CGGACGGTGA CCCCACTGTG GGAGAAACCA ACCCCACGAT TATCCAGAAC 
AACGTGCGGG AAGCCATCAA TGGGCAGTAT AGCCTCTTCT GCCTGGGGTT CGGCTTTGAT 
GTGAACTATC CTTTCCTGGA GAAGATGGCA CTGGACAATG GTGGCCTGGC CAGGCGCATC 
TATGAGGATT CAGACTCTGC ACTGCAGCTT CAGGATTTCT ACCACGAAGT AGCCAATCCA 
CTGCTCTCAT CAGTGGCCTT CGAATACCCC AGTGATGCTG TGGAGGAAGT CACTCGGTAC 
AAGTTCCAAC ACCACTTTAA GGGCTCAGAG ATGGTGGTGG CTGGGAAGCT CCAGGACCAG 
GGTCCTGATG TCCTCTTAGC CAAAGTCAGT GGGCAGATGC ACATGCAGAA CATCACTTTC 
CAAACGGAGG CCAGCGTAGC CCAACAAGAG AAGGAGTTTA AGAGCCCCAA GTACATCTTT 
CACAACTTTA TGGAGAGACT GTGGGCACTG CTGACTATAC AGCAACAGCT GGAGCAGAGG 
ATTTCAGCGT CAGGTGCCGA ATTAGAGGCC CTCGAGGCCC AAGTTCTGAA CTTGTCACTC 
AAGTACAATT TTGTCACCCC TCTCACGCAC ATGGTGGTCA CCAAACCTGA AGGTCAAGAA 
CAATTCCAAG TTGCTGAGAA GCCTGTGGAA GTCGGTGATG GCATGCAGAG ACTCCCCTTA 
GCAGCTCAAG CCCACCCCTT CAGGCCTCCT GTCAGAGGAT CTAAACTGAT GACCGTGCTG 
AAAGGAAGCA GGTCCCAGAT ACCCAGACTC GGTGATGCCG TTAGGGCATC TAGGCAATAC 
ATTCCTCCCG GATTCCCCGG ACCTCCTGGA CCTCCCGGAT TTCCTGCACC TCCTGGACCT 
CCTGGATTTC CTGCACCCCC TGGACCTCCT CTTGCTTCTG GCTCTGACTT CAGCCTTCAG 
CCTTCCTATG AAAGGATGCT AAGCCTGCCC TCCGTTGAAA GCACCATACC AGAGGAATCC 
CCAAACCCAG ACCACCCCCA GGTTCCTACT ATTACCTTGC CGCTTCCGGG ATCCAGTGTG 
GACCAGCTCT GTGTGGATAT CTTACATTCT GAGAAGCCCA TGAAGCTGTT CGTAGACCCC 
AGTCAGGGTC TGGAGGTGAC TGGTAAGTAT GAGAATACTG GGTTCTCGTG GCTCGAAGTG 
ACCATCCAGA AGCCTCACCT GCAGGTCCAT GCAACCCCTG AACGACTGGT GGTGACACGA 
GGCAGAAAAA ACACTGAATA CAAGTGGAAG AAGACGCTGT TCTCTGTGTT ACCTGGCTTG 
AAGATGACCA TGAATATGAT GGGACTCCTA CAGCTCAGTG GCCCAGACAA AGTCACCATC 
GGCCTCCTGT CCCTGGATGA CCCTCAGAGA GGACTAATGC TGCTTTTGAA TGACACCCAG 
CACTTCTCCA ACAACGTTAA AGGGGAGCTT GGTCAGTTTT ACCGGGACAT CGTCTGGGAG 
CCACCCGTCG AGCCAGATAA TACAAAACGG ACAGTCAAAG TTCAAGGAGT TGACTACCTG 
GCTACCAGAG AGCTCAAGTT GAGTTACCAA GAAGGGTTCC CAGGAGCAGA GATTTCCTGC 
TGGACAGTGG AGATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276561.1
CDS	54..2831
Translation	MKSPAPAHMWNLVLFLPSLLAVLPTTTAEKNGIDIYSLTVDSRVSSRFAHTVVTSRVVNRADAVQEATFQVELPRKAFITNFSMIIDGVTYPGVVKEKAEAQKQYSAAVGRGESAGIVKTTGRQTEKFEVSVNVAPGSKITFELIYQELLQRRLGMYELLLKVRPQQLVKHLQMDIYIFEPQGISILETESTFMTPELANALTTSQNKTKAHIRFKPTLSQQQKSQSEQDTVLNGDFIVRYDVNRSDSGGSIQIEEGYFVHHFAPENLPTMSKNVIFVIDKSGSMSGKKIQQTREALVKILKDLSPQDQFNLIEFSGEANQWKQSLVQATEENLNKAVNYASRIRAHGGTNINNAVLLAVELLDRSNQAELLPSKSVSLIILLTDGDPTVGETNPTIIQNNVREAINGQYSLFCLGFGFDVNYPFLEKMALDNGGLARRIYEDSDSALQLQDFYHEVANPLLSSVAFEYPSDAVEEVTRYKFQHHFKGSEMVVAGKLQDQGPDVLLAKVSGQMHMQNITFQTEASVAQQEKEFKSPKYIFHNFMERLWALLTIQQQLEQRISASGAELEALEAQVLNLSLKYNFVTPLTHMVVTKPEGQEQFQVAEKPVEVGDGMQRLPLAAQAHPFRPPVRGSKLMTVLKGSRSQIPRLGDAVRASRQYIPPGFPGPPGPPGFPAPPGPPGFPAPPGPPLASGSDFSLQPSYERMLSLPSVESTIPEESPNPDHPQVPTITLPLPGSSVDQLCVDILHSEKPMKLFVDPSQGLEVTGKYENTGFSWLEVTIQKPHLQVHATPERLVVTRGRKNTEYKWKKTLFSVLPGLKMTMNMMGLLQLSGPDKVTIGLLSLDDPQRGLMLLLNDTQHFSNNVKGELGQFYRDIVWEPPVEPDNTKRTVKVQGVDYLATRELKLSYQEGFPGAEISCWTVEI

Target ORF information:

RefSeq Version	NM_001289632.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus inter alpha-trypsin inhibitor, heavy chain 4 (Itih4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001289632.1

ORF Insert Sequence:

ATGAAGAGCC CTGCCCCTGC CCACATGTGG AACCTTGTGC TGTTCTTGCC TTCACTGTTG 
GCTGTGCTTC CGACCACTAC TGCCGAGAAG AATGGCATCG ATATCTACAG CCTCACGGTG 
GACTCCCGGG TCTCTTCCCG ATTTGCCCAT ACTGTTGTCA CCAGCCGGGT GGTCAACAGA 
GCCGATGCTG TTCAAGAAGC GACCTTCCAA GTAGAGCTAC CCAGGAAAGC CTTCATCACC 
AACTTTTCCA TGATCATCGA TGGCGTGACC TACCCAGGGG TTGTCAAAGA GAAGGCCGAA 
GCCCAGAAAC AATACAGTGC CGCCGTGGGC AGGGGAGAGA GTGCTGGCAT CGTCAAGACC 
ACTGGGAGGC AGACAGAGAA GTTTGAAGTG TCAGTCAACG TGGCCCCTGG TTCCAAGATT 
ACCTTCGAAC TCATATACCA GGAACTGCTC CAAAGGCGAC TGGGAATGTA TGAGCTACTC 
CTCAAAGTGA GGCCTCAGCA GCTGGTGAAG CACCTTCAGA TGGACATCTA CATCTTTGAG 
CCTCAGGGTA TTAGCATCCT GGAGACAGAG AGCACCTTCA TGACCCCGGA GCTGGCAAAT 
GCCCTTACCA CTTCACAGAA CAAGACCAAG GCTCATATCC GGTTCAAGCC GACGCTCTCC 
CAGCAACAGA AGTCTCAGAG TGAGCAGGAC ACGGTGCTGA ATGGGGACTT CATCGTCCGC 
TATGATGTCA ACCGGTCTGA CTCTGGGGGC TCCATTCAGA TTGAGGAAGG CTACTTTGTG 
CACCACTTTG CTCCAGAGAA CCTTCCTACA ATGTCCAAGA ATGTGATCTT TGTCATTGAT 
AAAAGCGGAT CTATGTCAGG CAAGAAAATC CAGCAGACCC GAGAAGCCCT AGTCAAGATC 
TTGAAAGACC TCAGCCCCCA AGACCAGTTC AACCTCATTG AGTTCAGTGG GGAAGCAAAC 
CAATGGAAGC AGTCACTGGT GCAAGCGACA GAAGAGAATT TGAACAAGGC TGTAAACTAT 
GCTTCCAGGA TCCGGGCTCA CGGAGGGACC AACATCAATA ATGCAGTGCT GTTGGCTGTG 
GAGCTGCTGG ACAGAAGCAA CCAAGCTGAG CTACTGCCCT CGAAGAGCGT CTCCCTTATC 
ATCCTGCTCA CGGACGGTGA CCCCACTGTG GGAGAAACCA ACCCCACGAT TATCCAGAAC 
AACGTGCGGG AAGCCATCAA TGGGCAGTAT AGCCTCTTCT GCCTGGGGTT CGGCTTTGAT 
GTGAACTATC CTTTCCTGGA GAAGATGGCA CTGGACAATG GTGGCCTGGC CAGGCGCATC 
TATGAGGATT CAGACTCTGC ACTGCAGCTT CAGGATTTCT ACCACGAAGT AGCCAATCCA 
CTGCTCTCAT CAGTGGCCTT CGAATACCCC AGTGATGCTG TGGAGGAAGT CACTCGGTAC 
AAGTTCCAAC ACCACTTTAA GGGCTCAGAG ATGGTGGTGG CTGGGAAGCT CCAGGACCAG 
GGTCCTGATG TCCTCTTAGC CAAAGTCAGT GGGCAGATGC ACATGCAGAA CATCACTTTC 
CAAACGGAGG CCAGCGTAGC CCAACAAGAG AAGGAGTTTA AGAGCCCCAA GTACATCTTT 
CACAACTTTA TGGAGAGACT GTGGGCACTG CTGACTATAC AGCAACAGCT GGAGCAGAGG 
ATTTCAGCGT CAGGTGCCGA ATTAGAGGCC CTCGAGGCCC AAGTTCTGAA CTTGTCACTC 
AAGTACAATT TTGTCACCCC TCTCACGCAC ATGGTGGTCA CCAAACCTGA AGGTCAAGAA 
CAATTCCAAG TTGCTGAGAA GCCTGTGGAA GTCGGTGATG GCATGCAGAG ACTCCCCTTA 
GCAGCTCAAG CCCACCCCTT CAGGCCTCCT GTCAGAGGAT CTAAACTGAT GACCGTGCTG 
AAAGGAAGCA GGTCCCAGAT ACCCAGACTC GGTGATGCCG TTAGGGCATC TAGGCAATAC 
ATTCCTCCCG GATTCCCCGG ACCTCCTGGA CCTCCCGGAT TTCCTGCACC TCCTGGACCT 
CCTGGATTTC CTGCACCCCC TGGACCTCCT CTTGCTTCTG GCTCTGACTT CAGCCTTCAG 
CCTTCCTATG AAAGGATGCT AAGCCTGCCC TCCGTTGAAA GCACCATACC AGAGGAATCC 
CCAAACCCAG ACCACCCCCA GGTTCCTACT ATTACCTTGC CGCTTCCGGG ATCCAGTGTG 
GACCAGCTCT GTGTGGATAT CTTACATTCT GAGAAGCCCA TGAAGCTGTT CGTAGACCCC 
AGTCAGGGTC TGGAGGTGAC TGGTAAGTAT GAGAATACTG GGTTCTCGTG GCTCGAAGTG 
ACCATCCAGA AGCCTCACCT GCAGGTCCAT GCAACCCCTG AACGACTGGT GGTGACACGA 
GGCAGAAAAA ACACTGAATA CAAGTGGAAG AAGACGCTGT TCTCTGTGTT ACCTGGCTTG 
AAGATGACCA TGAATATGAT GGGACTCCTA CAGCTCAGTG GCCCAGACAA AGTCACCATC 
GGCCTCCTGT CCCTGGATGA CCCTCAGAGA GGACTAATGC TGCTTTTGAA TGACACCCAG 
CACTTCTCCA ACAACGTTAA AGGGGAGCTT GGTCAGTTTT ACCGGGACAT CGTCTGGGAG 
CCACCCGTCG AGCCAGATAA TACAAAACGG ACAGTCAAAG TTCAAGGAGT TGACTACCTG 
GCTACCAGAG AGCTCAAGTT GAGTTACCAA GAAGGGTTCC CAGGAGCAGA GATTTCCTGC 
TGGACAGTGG AGATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Itih4 ( NM_001159299.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001152771.1 Mus musculus inter alpha-trypsin inhibitor, heavy chain 4 (Itih4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu57978
Clone ID Related Accession (Same CDS sequence)	NM_001159299.2
Accession Version	NM_001159299.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2826bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	inter alpha-trypsin inhibitor, heavy chain 4 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BY788238.1, AK050270.1 and BB809402.1. On Jan 24, 2014 this sequence version replaced NM_001159299.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This difference results in a protein (isoform 2) that is 1 amino acid shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK004862.1, BC016500.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGAGCC CTGCCCCTGC CCACATGTGG AACCTTGTGC TGTTCTTGCC TTCACTGTTG 
GCTGTGCTTC CGACCACTAC TGCCGAGAAG AATGGCATCG ATATCTACAG CCTCACGGTG 
GACTCCCGGG TCTCTTCCCG ATTTGCCCAT ACTGTTGTCA CCAGCCGGGT GGTCAACAGA 
GCCGATGCTG TTCAAGAAGC GACCTTCCAA GTAGAGCTAC CCAGGAAAGC CTTCATCACC 
AACTTTTCCA TGATCATCGA TGGCGTGACC TACCCAGGGG TTGTCAAAGA GAAGGCCGAA 
GCCCAGAAAC AATACAGTGC CGCCGTGGGC AGGGGAGAGA GTGCTGGCAT CGTCAAGACC 
ACTGGGAGGC AGACAGAGAA GTTTGAAGTG TCAGTCAACG TGGCCCCTGG TTCCAAGATT 
ACCTTCGAAC TCATATACCA GGAACTGCTC CAAAGGCGAC TGGGAATGTA TGAGCTACTC 
CTCAAAGTGA GGCCTCAGCA GCTGGTGAAG CACCTTCAGA TGGACATCTA CATCTTTGAG 
CCTCAGGGTA TTAGCATCCT GGAGACAGAG AGCACCTTCA TGACCCCGGA GCTGGCAAAT 
GCCCTTACCA CTTCACAGAA CAAGACCAAG GCTCATATCC GGTTCAAGCC GACGCTCTCC 
CAGCAACAGA AGTCTCAGAG TGAGCAGGAC ACGGTGCTGA ATGGGGACTT CATCGTCCGC 
TATGATGTCA ACCGGTCTGA CTCTGGGGGC TCCATTCAGA TTGAGGAAGG CTACTTTGTG 
CACCACTTTG CTCCAGAGAA CCTTCCTACA ATGTCCAAGA ATGTGATCTT TGTCATTGAT 
AAAAGCGGAT CTATGTCAGG CAAGAAAATC CAGCAGACCC GAGAAGCCCT AGTCAAGATC 
TTGAAAGACC TCAGCCCCCA AGACCAGTTC AACCTCATTG AGTTCAGTGG GGAAGCAAAC 
CAATGGAAGC AGTCACTGGT GCAAGCGACA GAAGAGAATT TGAACAAGGC TGTAAACTAT 
GCTTCCAGGA TCCGGGCTCA CGGAGGGACC AACATCAATA ATGCAGTGCT GTTGGCTGTG 
GAGCTGCTGG ACAGAAGCAA CCAAGCTGAG CTACTGCCCT CGAAGAGCGT CTCCCTTATC 
ATCCTGCTCA CGGACGGTGA CCCCACTGTG GGAGAAACCA ACCCCACGAT TATCCAGAAC 
AACGTGCGGG AAGCCATCAA TGGGCAGTAT AGCCTCTTCT GCCTGGGGTT CGGCTTTGAT 
GTGAACTATC CTTTCCTGGA GAAGATGGCA CTGGACAATG GTGGCCTGGC CAGGCGCATC 
TATGAGGATT CAGACTCTGC ACTGCAGCTT CAGGATTTCT ACCACGAAGT AGCCAATCCA 
CTGCTCTCAT CAGTGGCCTT CGAATACCCC AGTGATGCTG TGGAGGAAGT CACTCGGTAC 
AAGTTCCAAC ACCACTTTAA GGGCTCAGAG ATGGTGGTGG CTGGGAAGCT CCAGGACCAG 
GGTCCTGATG TCCTCTTAGC CAAAGTCAGT GGGCAGATGC ACATGCAGAA CATCACTTTC 
CAAACGGAGG CCAGCGTAGC CCAACAAGAG AAGGAGTTTA AGAGCCCCAA GTACATCTTT 
CACAACTTTA TGGAGAGACT GTGGGCACTG CTGACTATAC AGCAACAGCT GGAGCAGAGG 
ATTTCAGCGT CAGGTGCCGA ATTAGAGGCC CTCGAGGCCC AAGTTCTGAA CTTGTCACTC 
AAGTACAATT TTGTCACCCC TCTCACGCAC ATGGTGGTCA CCAAACCTGA AGGTCAAGAA 
CAATTCCAAG TTGCTGAGAA GCCTGTGGAA GTCGGTGATG GCATGCAGAG ACTCCCCTTA 
GCAGCTCAAG CCCACCCCTT CAGGCCTCCT GTCAGAGGAT CTAAACTGAT GACCGTGCTG 
AAAGGAAGCA GGTCCCAGAT ACCCAGACTC GGTGATGCCG TTAGGGCATC TAGGCAATAC 
ATTCCTCCCG GATTCCCCGG ACCTCCTGGA CCTCCCGGAT TTCCTGCACC TCCTGGACCT 
CCTGGATTTC CTGCACCCCC TGGACCTCCT CTTGCTTCTG GCTCTGACTT CAGCCTTCAG 
CCTTCCTATG AAAGGATGCT AAGCCTGCCC TCCGTTGCAC AATATCCTGC TGACCCACAT 
CTGGTTGTGA CGGAAAAAAG TAAAGAAAGC ACCATACCAG AGGAATCCCC AAACCCAGAC 
CACCCCCAGG TTCCTACTAT TACCTTGCCG CTTCCGGGAT CCAGTGTGGA CCAGCTCTGT 
GTGGATATCT TACATTCTGA GAAGCCCATG AAGCTGTTCG TAGACCCCAG TCAGGGTCTG 
GAGGTGACTG GTAAGTATGA GAATACTGGG TTCTCGTGGC TCGAAGTGAC CATCCAGAAG 
CCTCACCTGC AGGTCCATGC AACCCCTGAA CGACTGGTGG TGACACGAGG CAGAAAAAAC 
ACTGAATACA AGTGGAAGAA GACGCTGTTC TCTGTGTTAC CTGGCTTGAA GATGACCATG 
AATATGATGG GACTCCTACA GCTCAGTGGC CCAGACAAAG TCACCATCGG CCTCCTGTCC 
CTGGATGACC CTCAGAGAGG ACTAATGCTG CTTTTGAATG ACACCCAGCA CTTCTCCAAC 
AACGTTAAAG GGGAGCTTGG TCAGTTTTAC CGGGACATCG TCTGGGAGCC ACCCGTCGAG 
CCAGATAATA CAAAACGGAC AGTCAAAGTT CAAGGAGTTG ACTACCTGGC TACCAGAGAG 
CTCAAGTTGA GTTACCAAGA AGGGTTCCCA GGAGCAGAGA TTTCCTGCTG GACAGTGGAG 
ATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001152771.1
CDS	54..2879
Translation	MKSPAPAHMWNLVLFLPSLLAVLPTTTAEKNGIDIYSLTVDSRVSSRFAHTVVTSRVVNRADAVQEATFQVELPRKAFITNFSMIIDGVTYPGVVKEKAEAQKQYSAAVGRGESAGIVKTTGRQTEKFEVSVNVAPGSKITFELIYQELLQRRLGMYELLLKVRPQQLVKHLQMDIYIFEPQGISILETESTFMTPELANALTTSQNKTKAHIRFKPTLSQQQKSQSEQDTVLNGDFIVRYDVNRSDSGGSIQIEEGYFVHHFAPENLPTMSKNVIFVIDKSGSMSGKKIQQTREALVKILKDLSPQDQFNLIEFSGEANQWKQSLVQATEENLNKAVNYASRIRAHGGTNINNAVLLAVELLDRSNQAELLPSKSVSLIILLTDGDPTVGETNPTIIQNNVREAINGQYSLFCLGFGFDVNYPFLEKMALDNGGLARRIYEDSDSALQLQDFYHEVANPLLSSVAFEYPSDAVEEVTRYKFQHHFKGSEMVVAGKLQDQGPDVLLAKVSGQMHMQNITFQTEASVAQQEKEFKSPKYIFHNFMERLWALLTIQQQLEQRISASGAELEALEAQVLNLSLKYNFVTPLTHMVVTKPEGQEQFQVAEKPVEVGDGMQRLPLAAQAHPFRPPVRGSKLMTVLKGSRSQIPRLGDAVRASRQYIPPGFPGPPGPPGFPAPPGPPGFPAPPGPPLASGSDFSLQPSYERMLSLPSVAQYPADPHLVVTEKSKESTIPEESPNPDHPQVPTITLPLPGSSVDQLCVDILHSEKPMKLFVDPSQGLEVTGKYENTGFSWLEVTIQKPHLQVHATPERLVVTRGRKNTEYKWKKTLFSVLPGLKMTMNMMGLLQLSGPDKVTIGLLSLDDPQRGLMLLLNDTQHFSNNVKGELGQFYRDIVWEPPVEPDNTKRTVKVQGVDYLATRELKLSYQEGFPGAEISCWTVEI

Target ORF information:

RefSeq Version	NM_001159299.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus inter alpha-trypsin inhibitor, heavy chain 4 (Itih4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001159299.2

ORF Insert Sequence:

ATGAAGAGCC CTGCCCCTGC CCACATGTGG AACCTTGTGC TGTTCTTGCC TTCACTGTTG 
GCTGTGCTTC CGACCACTAC TGCCGAGAAG AATGGCATCG ATATCTACAG CCTCACGGTG 
GACTCCCGGG TCTCTTCCCG ATTTGCCCAT ACTGTTGTCA CCAGCCGGGT GGTCAACAGA 
GCCGATGCTG TTCAAGAAGC GACCTTCCAA GTAGAGCTAC CCAGGAAAGC CTTCATCACC 
AACTTTTCCA TGATCATCGA TGGCGTGACC TACCCAGGGG TTGTCAAAGA GAAGGCCGAA 
GCCCAGAAAC AATACAGTGC CGCCGTGGGC AGGGGAGAGA GTGCTGGCAT CGTCAAGACC 
ACTGGGAGGC AGACAGAGAA GTTTGAAGTG TCAGTCAACG TGGCCCCTGG TTCCAAGATT 
ACCTTCGAAC TCATATACCA GGAACTGCTC CAAAGGCGAC TGGGAATGTA TGAGCTACTC 
CTCAAAGTGA GGCCTCAGCA GCTGGTGAAG CACCTTCAGA TGGACATCTA CATCTTTGAG 
CCTCAGGGTA TTAGCATCCT GGAGACAGAG AGCACCTTCA TGACCCCGGA GCTGGCAAAT 
GCCCTTACCA CTTCACAGAA CAAGACCAAG GCTCATATCC GGTTCAAGCC GACGCTCTCC 
CAGCAACAGA AGTCTCAGAG TGAGCAGGAC ACGGTGCTGA ATGGGGACTT CATCGTCCGC 
TATGATGTCA ACCGGTCTGA CTCTGGGGGC TCCATTCAGA TTGAGGAAGG CTACTTTGTG 
CACCACTTTG CTCCAGAGAA CCTTCCTACA ATGTCCAAGA ATGTGATCTT TGTCATTGAT 
AAAAGCGGAT CTATGTCAGG CAAGAAAATC CAGCAGACCC GAGAAGCCCT AGTCAAGATC 
TTGAAAGACC TCAGCCCCCA AGACCAGTTC AACCTCATTG AGTTCAGTGG GGAAGCAAAC 
CAATGGAAGC AGTCACTGGT GCAAGCGACA GAAGAGAATT TGAACAAGGC TGTAAACTAT 
GCTTCCAGGA TCCGGGCTCA CGGAGGGACC AACATCAATA ATGCAGTGCT GTTGGCTGTG 
GAGCTGCTGG ACAGAAGCAA CCAAGCTGAG CTACTGCCCT CGAAGAGCGT CTCCCTTATC 
ATCCTGCTCA CGGACGGTGA CCCCACTGTG GGAGAAACCA ACCCCACGAT TATCCAGAAC 
AACGTGCGGG AAGCCATCAA TGGGCAGTAT AGCCTCTTCT GCCTGGGGTT CGGCTTTGAT 
GTGAACTATC CTTTCCTGGA GAAGATGGCA CTGGACAATG GTGGCCTGGC CAGGCGCATC 
TATGAGGATT CAGACTCTGC ACTGCAGCTT CAGGATTTCT ACCACGAAGT AGCCAATCCA 
CTGCTCTCAT CAGTGGCCTT CGAATACCCC AGTGATGCTG TGGAGGAAGT CACTCGGTAC 
AAGTTCCAAC ACCACTTTAA GGGCTCAGAG ATGGTGGTGG CTGGGAAGCT CCAGGACCAG 
GGTCCTGATG TCCTCTTAGC CAAAGTCAGT GGGCAGATGC ACATGCAGAA CATCACTTTC 
CAAACGGAGG CCAGCGTAGC CCAACAAGAG AAGGAGTTTA AGAGCCCCAA GTACATCTTT 
CACAACTTTA TGGAGAGACT GTGGGCACTG CTGACTATAC AGCAACAGCT GGAGCAGAGG 
ATTTCAGCGT CAGGTGCCGA ATTAGAGGCC CTCGAGGCCC AAGTTCTGAA CTTGTCACTC 
AAGTACAATT TTGTCACCCC TCTCACGCAC ATGGTGGTCA CCAAACCTGA AGGTCAAGAA 
CAATTCCAAG TTGCTGAGAA GCCTGTGGAA GTCGGTGATG GCATGCAGAG ACTCCCCTTA 
GCAGCTCAAG CCCACCCCTT CAGGCCTCCT GTCAGAGGAT CTAAACTGAT GACCGTGCTG 
AAAGGAAGCA GGTCCCAGAT ACCCAGACTC GGTGATGCCG TTAGGGCATC TAGGCAATAC 
ATTCCTCCCG GATTCCCCGG ACCTCCTGGA CCTCCCGGAT TTCCTGCACC TCCTGGACCT 
CCTGGATTTC CTGCACCCCC TGGACCTCCT CTTGCTTCTG GCTCTGACTT CAGCCTTCAG 
CCTTCCTATG AAAGGATGCT AAGCCTGCCC TCCGTTGCAC AATATCCTGC TGACCCACAT 
CTGGTTGTGA CGGAAAAAAG TAAAGAAAGC ACCATACCAG AGGAATCCCC AAACCCAGAC 
CACCCCCAGG TTCCTACTAT TACCTTGCCG CTTCCGGGAT CCAGTGTGGA CCAGCTCTGT 
GTGGATATCT TACATTCTGA GAAGCCCATG AAGCTGTTCG TAGACCCCAG TCAGGGTCTG 
GAGGTGACTG GTAAGTATGA GAATACTGGG TTCTCGTGGC TCGAAGTGAC CATCCAGAAG 
CCTCACCTGC AGGTCCATGC AACCCCTGAA CGACTGGTGG TGACACGAGG CAGAAAAAAC 
ACTGAATACA AGTGGAAGAA GACGCTGTTC TCTGTGTTAC CTGGCTTGAA GATGACCATG 
AATATGATGG GACTCCTACA GCTCAGTGGC CCAGACAAAG TCACCATCGG CCTCCTGTCC 
CTGGATGACC CTCAGAGAGG ACTAATGCTG CTTTTGAATG ACACCCAGCA CTTCTCCAAC 
AACGTTAAAG GGGAGCTTGG TCAGTTTTAC CGGGACATCG TCTGGGAGCC ACCCGTCGAG 
CCAGATAATA CAAAACGGAC AGTCAAAGTT CAAGGAGTTG ACTACCTGGC TACCAGAGAG 
CTCAAGTTGA GTTACCAAGA AGGGTTCCCA GGAGCAGAGA TTTCCTGCTG GACAGTGGAG 
ATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Itih4 ( NM_018746.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_061216.2 Mus musculus inter alpha-trypsin inhibitor, heavy chain 4 (Itih4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu57985
Clone ID Related Accession (Same CDS sequence)	NM_018746.4
Accession Version	NM_018746.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2829bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	inter alpha-trypsin inhibitor, heavy chain 4 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BY788238.1, AK050270.1 and BB809402.1. On Jan 24, 2014 this sequence version replaced NM_018746.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK050016.1, AK050270.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGAGCC CTGCCCCTGC CCACATGTGG AACCTTGTGC TGTTCTTGCC TTCACTGTTG 
GCTGTGCTTC CGACCACTAC TGCCGAGAAG AATGGCATCG ATATCTACAG CCTCACGGTG 
GACTCCCGGG TCTCTTCCCG ATTTGCCCAT ACTGTTGTCA CCAGCCGGGT GGTCAACAGA 
GCCGATGCTG TTCAAGAAGC GACCTTCCAA GTAGAGCTAC CCAGGAAAGC CTTCATCACC 
AACTTTTCCA TGATCATCGA TGGCGTGACC TACCCAGGGG TTGTCAAAGA GAAGGCCGAA 
GCCCAGAAAC AATACAGTGC CGCCGTGGGC AGGGGAGAGA GTGCTGGCAT CGTCAAGACC 
ACTGGGAGGC AGACAGAGAA GTTTGAAGTG TCAGTCAACG TGGCCCCTGG TTCCAAGATT 
ACCTTCGAAC TCATATACCA GGAACTGCTC CAAAGGCGAC TGGGAATGTA TGAGCTACTC 
CTCAAAGTGA GGCCTCAGCA GCTGGTGAAG CACCTTCAGA TGGACATCTA CATCTTTGAG 
CCTCAGGGTA TTAGCATCCT GGAGACAGAG AGCACCTTCA TGACCCCGGA GCTGGCAAAT 
GCCCTTACCA CTTCACAGAA CAAGACCAAG GCTCATATCC GGTTCAAGCC GACGCTCTCC 
CAGCAACAGA AGTCTCAGAG TGAGCAGGAC ACGGTGCTGA ATGGGGACTT CATCGTCCGC 
TATGATGTCA ACCGGTCTGA CTCTGGGGGC TCCATTCAGA TTGAGGAAGG CTACTTTGTG 
CACCACTTTG CTCCAGAGAA CCTTCCTACA ATGTCCAAGA ATGTGATCTT TGTCATTGAT 
AAAAGCGGAT CTATGTCAGG CAAGAAAATC CAGCAGACCC GAGAAGCCCT AGTCAAGATC 
TTGAAAGACC TCAGCCCCCA AGACCAGTTC AACCTCATTG AGTTCAGTGG GGAAGCAAAC 
CAATGGAAGC AGTCACTGGT GCAAGCGACA GAAGAGAATT TGAACAAGGC TGTAAACTAT 
GCTTCCAGGA TCCGGGCTCA CGGAGGGACC AACATCAATA ATGCAGTGCT GTTGGCTGTG 
GAGCTGCTGG ACAGAAGCAA CCAAGCTGAG CTACTGCCCT CGAAGAGCGT CTCCCTTATC 
ATCCTGCTCA CGGACGGTGA CCCCACTGTG GGAGAAACCA ACCCCACGAT TATCCAGAAC 
AACGTGCGGG AAGCCATCAA TGGGCAGTAT AGCCTCTTCT GCCTGGGGTT CGGCTTTGAT 
GTGAACTATC CTTTCCTGGA GAAGATGGCA CTGGACAATG GTGGCCTGGC CAGGCGCATC 
TATGAGGATT CAGACTCTGC ACTGCAGCTT CAGGATTTCT ACCACGAAGT AGCCAATCCA 
CTGCTCTCAT CAGTGGCCTT CGAATACCCC AGTGATGCTG TGGAGGAAGT CACTCGGTAC 
AAGTTCCAAC ACCACTTTAA GGGCTCAGAG ATGGTGGTGG CTGGGAAGCT CCAGGACCAG 
GGTCCTGATG TCCTCTTAGC CAAAGTCAGT GGGCAGATGC ACATGCAGAA CATCACTTTC 
CAAACGGAGG CCAGCGTAGC CCAACAAGAG AAGGAGTTTA AGAGCCCCAA GTACATCTTT 
CACAACTTTA TGGAGAGACT GTGGGCACTG CTGACTATAC AGCAACAGCT GGAGCAGAGG 
ATTTCAGCGT CAGGTGCCGA ATTAGAGGCC CTCGAGGCCC AAGTTCTGAA CTTGTCACTC 
AAGTACAATT TTGTCACCCC TCTCACGCAC ATGGTGGTCA CCAAACCTGA AGGTCAAGAA 
CAATTCCAAG TTGCTGAGAA GCCTGTGGAA GTCGGTGATG GCATGCAGAG ACTCCCCTTA 
GCAGCTCAAG CCCACCCCTT CAGGCCTCCT GTCAGAGGAT CTAAACTGAT GACCGTGCTG 
AAAGGAAGCA GGTCCCAGAT ACCCAGACTC GGTGATGCCG TTAGGGCATC TAGGCAATAC 
ATTCCTCCCG GATTCCCCGG ACCTCCTGGA CCTCCCGGAT TTCCTGCACC TCCTGGACCT 
CCTGGATTTC CTGCACCCCC TGGACCTCCT CTTGCTTCTG GCTCTGACTT CAGCCTTCAG 
CCTTCCTATG AAAGGATGCT AAGCCTGCCC TCCGTTGCAG CACAATATCC TGCTGACCCA 
CATCTGGTTG TGACGGAAAA AAGTAAAGAA AGCACCATAC CAGAGGAATC CCCAAACCCA 
GACCACCCCC AGGTTCCTAC TATTACCTTG CCGCTTCCGG GATCCAGTGT GGACCAGCTC 
TGTGTGGATA TCTTACATTC TGAGAAGCCC ATGAAGCTGT TCGTAGACCC CAGTCAGGGT 
CTGGAGGTGA CTGGTAAGTA TGAGAATACT GGGTTCTCGT GGCTCGAAGT GACCATCCAG 
AAGCCTCACC TGCAGGTCCA TGCAACCCCT GAACGACTGG TGGTGACACG AGGCAGAAAA 
AACACTGAAT ACAAGTGGAA GAAGACGCTG TTCTCTGTGT TACCTGGCTT GAAGATGACC 
ATGAATATGA TGGGACTCCT ACAGCTCAGT GGCCCAGACA AAGTCACCAT CGGCCTCCTG 
TCCCTGGATG ACCCTCAGAG AGGACTAATG CTGCTTTTGA ATGACACCCA GCACTTCTCC 
AACAACGTTA AAGGGGAGCT TGGTCAGTTT TACCGGGACA TCGTCTGGGA GCCACCCGTC 
GAGCCAGATA ATACAAAACG GACAGTCAAA GTTCAAGGAG TTGACTACCT GGCTACCAGA 
GAGCTCAAGT TGAGTTACCA AGAAGGGTTC CCAGGAGCAG AGATTTCCTG CTGGACAGTG 
GAGATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061216.2
CDS	54..2882
Translation	MKSPAPAHMWNLVLFLPSLLAVLPTTTAEKNGIDIYSLTVDSRVSSRFAHTVVTSRVVNRADAVQEATFQVELPRKAFITNFSMIIDGVTYPGVVKEKAEAQKQYSAAVGRGESAGIVKTTGRQTEKFEVSVNVAPGSKITFELIYQELLQRRLGMYELLLKVRPQQLVKHLQMDIYIFEPQGISILETESTFMTPELANALTTSQNKTKAHIRFKPTLSQQQKSQSEQDTVLNGDFIVRYDVNRSDSGGSIQIEEGYFVHHFAPENLPTMSKNVIFVIDKSGSMSGKKIQQTREALVKILKDLSPQDQFNLIEFSGEANQWKQSLVQATEENLNKAVNYASRIRAHGGTNINNAVLLAVELLDRSNQAELLPSKSVSLIILLTDGDPTVGETNPTIIQNNVREAINGQYSLFCLGFGFDVNYPFLEKMALDNGGLARRIYEDSDSALQLQDFYHEVANPLLSSVAFEYPSDAVEEVTRYKFQHHFKGSEMVVAGKLQDQGPDVLLAKVSGQMHMQNITFQTEASVAQQEKEFKSPKYIFHNFMERLWALLTIQQQLEQRISASGAELEALEAQVLNLSLKYNFVTPLTHMVVTKPEGQEQFQVAEKPVEVGDGMQRLPLAAQAHPFRPPVRGSKLMTVLKGSRSQIPRLGDAVRASRQYIPPGFPGPPGPPGFPAPPGPPGFPAPPGPPLASGSDFSLQPSYERMLSLPSVAAQYPADPHLVVTEKSKESTIPEESPNPDHPQVPTITLPLPGSSVDQLCVDILHSEKPMKLFVDPSQGLEVTGKYENTGFSWLEVTIQKPHLQVHATPERLVVTRGRKNTEYKWKKTLFSVLPGLKMTMNMMGLLQLSGPDKVTIGLLSLDDPQRGLMLLLNDTQHFSNNVKGELGQFYRDIVWEPPVEPDNTKRTVKVQGVDYLATRELKLSYQEGFPGAEISCWTVEI

Target ORF information:

RefSeq Version	NM_018746.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus inter alpha-trypsin inhibitor, heavy chain 4 (Itih4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018746.4

ORF Insert Sequence:

ATGAAGAGCC CTGCCCCTGC CCACATGTGG AACCTTGTGC TGTTCTTGCC TTCACTGTTG 
GCTGTGCTTC CGACCACTAC TGCCGAGAAG AATGGCATCG ATATCTACAG CCTCACGGTG 
GACTCCCGGG TCTCTTCCCG ATTTGCCCAT ACTGTTGTCA CCAGCCGGGT GGTCAACAGA 
GCCGATGCTG TTCAAGAAGC GACCTTCCAA GTAGAGCTAC CCAGGAAAGC CTTCATCACC 
AACTTTTCCA TGATCATCGA TGGCGTGACC TACCCAGGGG TTGTCAAAGA GAAGGCCGAA 
GCCCAGAAAC AATACAGTGC CGCCGTGGGC AGGGGAGAGA GTGCTGGCAT CGTCAAGACC 
ACTGGGAGGC AGACAGAGAA GTTTGAAGTG TCAGTCAACG TGGCCCCTGG TTCCAAGATT 
ACCTTCGAAC TCATATACCA GGAACTGCTC CAAAGGCGAC TGGGAATGTA TGAGCTACTC 
CTCAAAGTGA GGCCTCAGCA GCTGGTGAAG CACCTTCAGA TGGACATCTA CATCTTTGAG 
CCTCAGGGTA TTAGCATCCT GGAGACAGAG AGCACCTTCA TGACCCCGGA GCTGGCAAAT 
GCCCTTACCA CTTCACAGAA CAAGACCAAG GCTCATATCC GGTTCAAGCC GACGCTCTCC 
CAGCAACAGA AGTCTCAGAG TGAGCAGGAC ACGGTGCTGA ATGGGGACTT CATCGTCCGC 
TATGATGTCA ACCGGTCTGA CTCTGGGGGC TCCATTCAGA TTGAGGAAGG CTACTTTGTG 
CACCACTTTG CTCCAGAGAA CCTTCCTACA ATGTCCAAGA ATGTGATCTT TGTCATTGAT 
AAAAGCGGAT CTATGTCAGG CAAGAAAATC CAGCAGACCC GAGAAGCCCT AGTCAAGATC 
TTGAAAGACC TCAGCCCCCA AGACCAGTTC AACCTCATTG AGTTCAGTGG GGAAGCAAAC 
CAATGGAAGC AGTCACTGGT GCAAGCGACA GAAGAGAATT TGAACAAGGC TGTAAACTAT 
GCTTCCAGGA TCCGGGCTCA CGGAGGGACC AACATCAATA ATGCAGTGCT GTTGGCTGTG 
GAGCTGCTGG ACAGAAGCAA CCAAGCTGAG CTACTGCCCT CGAAGAGCGT CTCCCTTATC 
ATCCTGCTCA CGGACGGTGA CCCCACTGTG GGAGAAACCA ACCCCACGAT TATCCAGAAC 
AACGTGCGGG AAGCCATCAA TGGGCAGTAT AGCCTCTTCT GCCTGGGGTT CGGCTTTGAT 
GTGAACTATC CTTTCCTGGA GAAGATGGCA CTGGACAATG GTGGCCTGGC CAGGCGCATC 
TATGAGGATT CAGACTCTGC ACTGCAGCTT CAGGATTTCT ACCACGAAGT AGCCAATCCA 
CTGCTCTCAT CAGTGGCCTT CGAATACCCC AGTGATGCTG TGGAGGAAGT CACTCGGTAC 
AAGTTCCAAC ACCACTTTAA GGGCTCAGAG ATGGTGGTGG CTGGGAAGCT CCAGGACCAG 
GGTCCTGATG TCCTCTTAGC CAAAGTCAGT GGGCAGATGC ACATGCAGAA CATCACTTTC 
CAAACGGAGG CCAGCGTAGC CCAACAAGAG AAGGAGTTTA AGAGCCCCAA GTACATCTTT 
CACAACTTTA TGGAGAGACT GTGGGCACTG CTGACTATAC AGCAACAGCT GGAGCAGAGG 
ATTTCAGCGT CAGGTGCCGA ATTAGAGGCC CTCGAGGCCC AAGTTCTGAA CTTGTCACTC 
AAGTACAATT TTGTCACCCC TCTCACGCAC ATGGTGGTCA CCAAACCTGA AGGTCAAGAA 
CAATTCCAAG TTGCTGAGAA GCCTGTGGAA GTCGGTGATG GCATGCAGAG ACTCCCCTTA 
GCAGCTCAAG CCCACCCCTT CAGGCCTCCT GTCAGAGGAT CTAAACTGAT GACCGTGCTG 
AAAGGAAGCA GGTCCCAGAT ACCCAGACTC GGTGATGCCG TTAGGGCATC TAGGCAATAC 
ATTCCTCCCG GATTCCCCGG ACCTCCTGGA CCTCCCGGAT TTCCTGCACC TCCTGGACCT 
CCTGGATTTC CTGCACCCCC TGGACCTCCT CTTGCTTCTG GCTCTGACTT CAGCCTTCAG 
CCTTCCTATG AAAGGATGCT AAGCCTGCCC TCCGTTGCAG CACAATATCC TGCTGACCCA 
CATCTGGTTG TGACGGAAAA AAGTAAAGAA AGCACCATAC CAGAGGAATC CCCAAACCCA 
GACCACCCCC AGGTTCCTAC TATTACCTTG CCGCTTCCGG GATCCAGTGT GGACCAGCTC 
TGTGTGGATA TCTTACATTC TGAGAAGCCC ATGAAGCTGT TCGTAGACCC CAGTCAGGGT 
CTGGAGGTGA CTGGTAAGTA TGAGAATACT GGGTTCTCGT GGCTCGAAGT GACCATCCAG 
AAGCCTCACC TGCAGGTCCA TGCAACCCCT GAACGACTGG TGGTGACACG AGGCAGAAAA 
AACACTGAAT ACAAGTGGAA GAAGACGCTG TTCTCTGTGT TACCTGGCTT GAAGATGACC 
ATGAATATGA TGGGACTCCT ACAGCTCAGT GGCCCAGACA AAGTCACCAT CGGCCTCCTG 
TCCCTGGATG ACCCTCAGAG AGGACTAATG CTGCTTTTGA ATGACACCCA GCACTTCTCC 
AACAACGTTA AAGGGGAGCT TGGTCAGTTT TACCGGGACA TCGTCTGGGA GCCACCCGTC 
GAGCCAGATA ATACAAAACG GACAGTCAAA GTTCAAGGAG TTGACTACCT GGCTACCAGA 
GAGCTCAAGT TGAGTTACCA AGAAGGGTTC CCAGGAGCAG AGATTTCCTG CTGGACAGTG 
GAGATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Itih4 ( NM_001289633.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001276562.1 Mus musculus inter alpha-trypsin inhibitor, heavy chain 4 (Itih4), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OMu58025
Clone ID Related Accession (Same CDS sequence)	NM_001289633.1
Accession Version	NM_001289633.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2709bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-04
Organism	Mus musculus(house mouse)
Product	inter alpha-trypsin inhibitor, heavy chain 4 isoform 4 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BY788238.1, AK004893.1 and BB809402.1. Transcript Variant: This variant (4) uses an alternate in-frame splice site and lacks an in-frame exon in the 3' coding region, compared to variant 1. This difference results in a shorter protein (isoform 4), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK004893.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849386, SAMN01164135 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGAGCC CTGCCCCTGC CCACATGTGG AACCTTGTGC TGTTCTTGCC TTCACTGTTG 
GCTGTGCTTC CGACCACTAC TGCCGAGAAG AATGGCATCG ATATCTACAG CCTCACGGTG 
GACTCCCGGG TCTCTTCCCG ATTTGCCCAT ACTGTTGTCA CCAGCCGGGT GGTCAACAGA 
GCCGATGCTG TTCAAGAAGC GACCTTCCAA GTAGAGCTAC CCAGGAAAGC CTTCATCACC 
AACTTTTCCA TGATCATCGA TGGCGTGACC TACCCAGGGG TTGTCAAAGA GAAGGCCGAA 
GCCCAGAAAC AATACAGTGC CGCCGTGGGC AGGGGAGAGA GTGCTGGCAT CGTCAAGACC 
ACTGGGAGGC AGACAGAGAA GTTTGAAGTG TCAGTCAACG TGGCCCCTGG TTCCAAGATT 
ACCTTCGAAC TCATATACCA GGAACTGCTC CAAAGGCGAC TGGGAATGTA TGAGCTACTC 
CTCAAAGTGA GGCCTCAGCA GCTGGTGAAG CACCTTCAGA TGGACATCTA CATCTTTGAG 
CCTCAGGGTA TTAGCATCCT GGAGACAGAG AGCACCTTCA TGACCCCGGA GCTGGCAAAT 
GCCCTTACCA CTTCACAGAA CAAGACCAAG GCTCATATCC GGTTCAAGCC GACGCTCTCC 
CAGCAACAGA AGTCTCAGAG TGAGCAGGAC ACGGTGCTGA ATGGGGACTT CATCGTCCGC 
TATGATGTCA ACCGGTCTGA CTCTGGGGGC TCCATTCAGA TTGAGGAAGG CTACTTTGTG 
CACCACTTTG CTCCAGAGAA CCTTCCTACA ATGTCCAAGA ATGTGATCTT TGTCATTGAT 
AAAAGCGGAT CTATGTCAGG CAAGAAAATC CAGCAGACCC GAGAAGCCCT AGTCAAGATC 
TTGAAAGACC TCAGCCCCCA AGACCAGTTC AACCTCATTG AGTTCAGTGG GGAAGCAAAC 
CAATGGAAGC AGTCACTGGT GCAAGCGACA GAAGAGAATT TGAACAAGGC TGTAAACTAT 
GCTTCCAGGA TCCGGGCTCA CGGAGGGACC AACATCAATA ATGCAGTGCT GTTGGCTGTG 
GAGCTGCTGG ACAGAAGCAA CCAAGCTGAG CTACTGCCCT CGAAGAGCGT CTCCCTTATC 
ATCCTGCTCA CGGACGGTGA CCCCACTGTG GGAGAAACCA ACCCCACGAT TATCCAGAAC 
AACGTGCGGG AAGCCATCAA TGGGCAGTAT AGCCTCTTCT GCCTGGGGTT CGGCTTTGAT 
GTGAACTATC CTTTCCTGGA GAAGATGGCA CTGGACAATG GTGGCCTGGC CAGGCGCATC 
TATGAGGATT CAGACTCTGC ACTGCAGCTT CAGGATTTCT ACCACGAAGT AGCCAATCCA 
CTGCTCTCAT CAGTGGCCTT CGAATACCCC AGTGATGCTG TGGAGGAAGT CACTCGGTAC 
AAGTTCCAAC ACCACTTTAA GGGCTCAGAG ATGGTGGTGG CTGGGAAGCT CCAGGACCAG 
GGTCCTGATG TCCTCTTAGC CAAAGTCAGT GGGCAGATGC ACATGCAGAA CATCACTTTC 
CAAACGGAGG CCAGCGTAGC CCAACAAGAG AAGGAGTTTA AGAGCCCCAA GTACATCTTT 
CACAACTTTA TGGAGAGACT GTGGGCACTG CTGACTATAC AGCAACAGCT GGAGCAGAGG 
ATTTCAGCGT CAGGTGCCGA ATTAGAGGCC CTCGAGGCCC AAGTTCTGAA CTTGTCACTC 
AAGTACAATT TTGTCACCCC TCTCACGCAC ATGGTGGTCA CCAAACCTGA AGGTCAAGAA 
CAATTCCAAG TTGCTGAGAA GCCTGTGGAA GTCGGTGATG GCATGCAGAG ACTCCCCTTA 
GCAGCTCAAG CCCACCCCTT CAGGCCTCCT GTCAGAGGAT CTAAACTGAT GACCGTGCTG 
AAAGGAAGCA GGTCCCAGAT ACCCAGACTC GGTGATGCCG TTAGGGCATC TAGGCAATAC 
ATTCCTCCCG GATTCCCCGG ACCTCCTGGA CCTCCCGGAT TTCCTGCACC TCCTGGACCT 
CCTGGATTTC CTGCACCCCC TGGACCTCCT CTTGCTTCTG GCTCTGACTT CAGCCTTCAG 
CCTTCCTATG AAAGGATGCT AAGCCTGCCC TCCGTTGCAC AATATCCTGC TGACCCACAT 
CTGGTTGTGA CGGAAAAAAG TAAAGAAAGC ACCATACCAG AGGAATCCCC AAACCCAGGT 
CTGGAGGTGA CTGGTAAGTA TGAGAATACT GGGTTCTCGT GGCTCGAAGT GACCATCCAG 
AAGCCTCACC TGCAGGTCCA TGCAACCCCT GAACGACTGG TGGTGACACG AGGCAGAAAA 
AACACTGAAT ACAAGTGGAA GAAGACGCTG TTCTCTGTGT TACCTGGCTT GAAGATGACC 
ATGAATATGA TGGGACTCCT ACAGCTCAGT GGCCCAGACA AAGTCACCAT CGGCCTCCTG 
TCCCTGGATG ACCCTCAGAG AGGACTAATG CTGCTTTTGA ATGACACCCA GCACTTCTCC 
AACAACGTTA AAGGGGAGCT TGGTCAGTTT TACCGGGACA TCGTCTGGGA GCCACCCGTC 
GAGCCAGATA ATACAAAACG GACAGTCAAA GTTCAAGGAG TTGACTACCT GGCTACCAGA 
GAGCTCAAGT TGAGTTACCA AGAAGGGTTC CCAGGAGCAG AGATTTCCTG CTGGACAGTG 
GAGATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276562.1
CDS	54..2762
Translation	MKSPAPAHMWNLVLFLPSLLAVLPTTTAEKNGIDIYSLTVDSRVSSRFAHTVVTSRVVNRADAVQEATFQVELPRKAFITNFSMIIDGVTYPGVVKEKAEAQKQYSAAVGRGESAGIVKTTGRQTEKFEVSVNVAPGSKITFELIYQELLQRRLGMYELLLKVRPQQLVKHLQMDIYIFEPQGISILETESTFMTPELANALTTSQNKTKAHIRFKPTLSQQQKSQSEQDTVLNGDFIVRYDVNRSDSGGSIQIEEGYFVHHFAPENLPTMSKNVIFVIDKSGSMSGKKIQQTREALVKILKDLSPQDQFNLIEFSGEANQWKQSLVQATEENLNKAVNYASRIRAHGGTNINNAVLLAVELLDRSNQAELLPSKSVSLIILLTDGDPTVGETNPTIIQNNVREAINGQYSLFCLGFGFDVNYPFLEKMALDNGGLARRIYEDSDSALQLQDFYHEVANPLLSSVAFEYPSDAVEEVTRYKFQHHFKGSEMVVAGKLQDQGPDVLLAKVSGQMHMQNITFQTEASVAQQEKEFKSPKYIFHNFMERLWALLTIQQQLEQRISASGAELEALEAQVLNLSLKYNFVTPLTHMVVTKPEGQEQFQVAEKPVEVGDGMQRLPLAAQAHPFRPPVRGSKLMTVLKGSRSQIPRLGDAVRASRQYIPPGFPGPPGPPGFPAPPGPPGFPAPPGPPLASGSDFSLQPSYERMLSLPSVAQYPADPHLVVTEKSKESTIPEESPNPGLEVTGKYENTGFSWLEVTIQKPHLQVHATPERLVVTRGRKNTEYKWKKTLFSVLPGLKMTMNMMGLLQLSGPDKVTIGLLSLDDPQRGLMLLLNDTQHFSNNVKGELGQFYRDIVWEPPVEPDNTKRTVKVQGVDYLATRELKLSYQEGFPGAEISCWTVEI

Target ORF information:

RefSeq Version	NM_001289633.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus inter alpha-trypsin inhibitor, heavy chain 4 (Itih4), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001289633.1

ORF Insert Sequence:

ATGAAGAGCC CTGCCCCTGC CCACATGTGG AACCTTGTGC TGTTCTTGCC TTCACTGTTG 
GCTGTGCTTC CGACCACTAC TGCCGAGAAG AATGGCATCG ATATCTACAG CCTCACGGTG 
GACTCCCGGG TCTCTTCCCG ATTTGCCCAT ACTGTTGTCA CCAGCCGGGT GGTCAACAGA 
GCCGATGCTG TTCAAGAAGC GACCTTCCAA GTAGAGCTAC CCAGGAAAGC CTTCATCACC 
AACTTTTCCA TGATCATCGA TGGCGTGACC TACCCAGGGG TTGTCAAAGA GAAGGCCGAA 
GCCCAGAAAC AATACAGTGC CGCCGTGGGC AGGGGAGAGA GTGCTGGCAT CGTCAAGACC 
ACTGGGAGGC AGACAGAGAA GTTTGAAGTG TCAGTCAACG TGGCCCCTGG TTCCAAGATT 
ACCTTCGAAC TCATATACCA GGAACTGCTC CAAAGGCGAC TGGGAATGTA TGAGCTACTC 
CTCAAAGTGA GGCCTCAGCA GCTGGTGAAG CACCTTCAGA TGGACATCTA CATCTTTGAG 
CCTCAGGGTA TTAGCATCCT GGAGACAGAG AGCACCTTCA TGACCCCGGA GCTGGCAAAT 
GCCCTTACCA CTTCACAGAA CAAGACCAAG GCTCATATCC GGTTCAAGCC GACGCTCTCC 
CAGCAACAGA AGTCTCAGAG TGAGCAGGAC ACGGTGCTGA ATGGGGACTT CATCGTCCGC 
TATGATGTCA ACCGGTCTGA CTCTGGGGGC TCCATTCAGA TTGAGGAAGG CTACTTTGTG 
CACCACTTTG CTCCAGAGAA CCTTCCTACA ATGTCCAAGA ATGTGATCTT TGTCATTGAT 
AAAAGCGGAT CTATGTCAGG CAAGAAAATC CAGCAGACCC GAGAAGCCCT AGTCAAGATC 
TTGAAAGACC TCAGCCCCCA AGACCAGTTC AACCTCATTG AGTTCAGTGG GGAAGCAAAC 
CAATGGAAGC AGTCACTGGT GCAAGCGACA GAAGAGAATT TGAACAAGGC TGTAAACTAT 
GCTTCCAGGA TCCGGGCTCA CGGAGGGACC AACATCAATA ATGCAGTGCT GTTGGCTGTG 
GAGCTGCTGG ACAGAAGCAA CCAAGCTGAG CTACTGCCCT CGAAGAGCGT CTCCCTTATC 
ATCCTGCTCA CGGACGGTGA CCCCACTGTG GGAGAAACCA ACCCCACGAT TATCCAGAAC 
AACGTGCGGG AAGCCATCAA TGGGCAGTAT AGCCTCTTCT GCCTGGGGTT CGGCTTTGAT 
GTGAACTATC CTTTCCTGGA GAAGATGGCA CTGGACAATG GTGGCCTGGC CAGGCGCATC 
TATGAGGATT CAGACTCTGC ACTGCAGCTT CAGGATTTCT ACCACGAAGT AGCCAATCCA 
CTGCTCTCAT CAGTGGCCTT CGAATACCCC AGTGATGCTG TGGAGGAAGT CACTCGGTAC 
AAGTTCCAAC ACCACTTTAA GGGCTCAGAG ATGGTGGTGG CTGGGAAGCT CCAGGACCAG 
GGTCCTGATG TCCTCTTAGC CAAAGTCAGT GGGCAGATGC ACATGCAGAA CATCACTTTC 
CAAACGGAGG CCAGCGTAGC CCAACAAGAG AAGGAGTTTA AGAGCCCCAA GTACATCTTT 
CACAACTTTA TGGAGAGACT GTGGGCACTG CTGACTATAC AGCAACAGCT GGAGCAGAGG 
ATTTCAGCGT CAGGTGCCGA ATTAGAGGCC CTCGAGGCCC AAGTTCTGAA CTTGTCACTC 
AAGTACAATT TTGTCACCCC TCTCACGCAC ATGGTGGTCA CCAAACCTGA AGGTCAAGAA 
CAATTCCAAG TTGCTGAGAA GCCTGTGGAA GTCGGTGATG GCATGCAGAG ACTCCCCTTA 
GCAGCTCAAG CCCACCCCTT CAGGCCTCCT GTCAGAGGAT CTAAACTGAT GACCGTGCTG 
AAAGGAAGCA GGTCCCAGAT ACCCAGACTC GGTGATGCCG TTAGGGCATC TAGGCAATAC 
ATTCCTCCCG GATTCCCCGG ACCTCCTGGA CCTCCCGGAT TTCCTGCACC TCCTGGACCT 
CCTGGATTTC CTGCACCCCC TGGACCTCCT CTTGCTTCTG GCTCTGACTT CAGCCTTCAG 
CCTTCCTATG AAAGGATGCT AAGCCTGCCC TCCGTTGCAC AATATCCTGC TGACCCACAT 
CTGGTTGTGA CGGAAAAAAG TAAAGAAAGC ACCATACCAG AGGAATCCCC AAACCCAGGT 
CTGGAGGTGA CTGGTAAGTA TGAGAATACT GGGTTCTCGT GGCTCGAAGT GACCATCCAG 
AAGCCTCACC TGCAGGTCCA TGCAACCCCT GAACGACTGG TGGTGACACG AGGCAGAAAA 
AACACTGAAT ACAAGTGGAA GAAGACGCTG TTCTCTGTGT TACCTGGCTT GAAGATGACC 
ATGAATATGA TGGGACTCCT ACAGCTCAGT GGCCCAGACA AAGTCACCAT CGGCCTCCTG 
TCCCTGGATG ACCCTCAGAG AGGACTAATG CTGCTTTTGA ATGACACCCA GCACTTCTCC 
AACAACGTTA AAGGGGAGCT TGGTCAGTTT TACCGGGACA TCGTCTGGGA GCCACCCGTC 
GAGCCAGATA ATACAAAACG GACAGTCAAA GTTCAAGGAG TTGACTACCT GGCTACCAGA 
GAGCTCAAGT TGAGTTACCA AGAAGGGTTC CCAGGAGCAG AGATTTCCTG CTGGACAGTG 
GAGATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.
Scientific reports740495(2017 Jan)
Naba A,Clauser KR,Mani DR,Carr SA,Hynes RO

Conformational changes in inter-?-trypsin inhibitor heavy chain 4 activate its tumor-specific activity in mice with B16 melanoma.
Molecular medicine reports12(3)4483-93(2015 Sep)
Kormosh NG,Davidova TV,Kopyltsov VN,Serebryakova MV,Kabieva AO,Voyushin KE,Sitdikova SM,Amandzholov BS,Kiselevskii MV,Donenko FV

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.
Molecular & cellular proteomics : MCP11(4)M111.014647(2012 Apr)
Naba A,Clauser KR,Hoersch S,Liu H,Carr SA,Hynes RO

Progenitor/stem cells give rise to liver cancer due to aberrant TGF-beta and IL-6 signaling.
Proceedings of the National Academy of Sciences of the United States of America105(7)2445-50(2008 Feb)
Tang Y,Kitisin K,Jogunoori W,Li C,Deng CX,Mueller SC,Ressom HW,Rashid A,He AR,Mendelson JS,Jessup JM,Shetty K,Zasloff M,Mishra B,Reddy EP,Johnson L,Mishra L

BIP co-chaperone MTJ1/ERDJ1 interacts with inter-alpha-trypsin inhibitor heavy chain 4.
Biochemical and biophysical research communications338(3)1467-77(2005 Dec)
Kroczynska B,King-Simmons L,Alloza L,Alava MA,Elguindi EC,Blond SY

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Itih4 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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