Inpp5b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Inpp5b
Entrez Gene ID	16330
Full Name	inositol polyphosphate-5-phosphatase B
Synonyms	5PTase,AW260155,INPP5P
General protein information	Preferred Names inositol polyphosphate-5-phosphatase B Names type II inositol 1,4,5-trisphosphate 5-phosphatase inositol polyphosphate-5-phosphatase, 75 kDa phosphoinositide 5-phosphatase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4 D2.2\|4 57.89 cM
Summary	This gene encodes a member of the inositol polyphosphate-5-phosphatase (INPP5) family. This protein hydrolyzes the 5' phosphate from phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol-1,4,5-trisphosphate, which results in changes to multiple signaling pathways. This protein may be involved in protein trafficking and secretion. Homozygous knockout mice exhibit impaired spermatogenesis and male sterility. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2014].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006502804.3	XP_006502867.1	type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1
XM_006502809.3	XP_006502872.1	type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X3
XM_006502805.2	XP_006502868.1	type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1
NM_008385.4	NP_032411.3	type II inositol 1,4,5-trisphosphate 5-phosphatase precursor
XM_011240450.2	XP_011238752.1	type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Inpp5b	NP_032411.3
Gallus gallus (chicken)	INPP5B	XP_417756.4
Oryza sativa (rice)	Os08g0425500	NP_001061838.1
Bos taurus (cattle)	INPP5B	XP_002686512.2
Danio rerio (zebrafish)	LOC563543	XP_692000.4
Xenopus tropicalis (tropical clawed frog)	LOC100497120	XP_004911650.1
Homo sapiens (human)	INPP5B	NP_005531.2
Pan troglodytes (chimpanzee)	INPP5B	XP_513330.4
Oryza sativa (rice)	Os09g0394600	NP_001063094.1
Canis lupus familiaris (dog)	INPP5B	XP_005628985.1
Rattus norvegicus (Norway rat)	Inpp5b	NP_001094225.1
Caenorhabditis elegans (roundworm)	ocrl-1	NP_001122420.1

Gene Ontology
Bibliography

Related articles in PubMed

Kidney Tubular Ablation of
Inoue K, Balkin DM, Liu L, Nandez R, Wu Y, Tian X, Wang T, Nussbaum R, De Camilli P, Ishibe S
Journal of the American Society of Nephrology : JASN28(5)1399-1407(2017 May)

Mouse model for Lowe syndrome/Dent Disease 2 renal tubulopathy.
Bothwell SP, Chan E, Bernardini IM, Kuo YM, Gahl WA, Nussbaum RL
Journal of the American Society of Nephrology : JASN22(3)443-8(2011 Mar)

Species-specific difference in expression and splice-site choice in Inpp5b, an inositol polyphosphate 5-phosphatase paralogous to the enzyme deficient in Lowe Syndrome.
Bothwell SP, Farber LW, Hoagland A, Nussbaum RL
Mammalian genome : official journal of the International Mammalian Genome Society21(9-10)458-66(2010 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results suggest that the functions of OCRL/INPP5B and proton-chloride exchange transporter 5 converge on shared mechanisms, the impairment of which has a dramatic effect on proximal tubule endocytosis
Title: Kidney Tubular Ablation of

study found mouse Inpp5b and human INPP5B differ in their transcription, splicing and amino acid sequence; observations form foundation for analyzing the functional basis for the difference in how Inpp5b and INPP5B compensate for loss of Ocrl function
Title: Species-specific difference in expression and splice-site choice in Inpp5b, an inositol polyphosphate 5-phosphatase paralogous to the enzyme deficient in Lowe Syndrome.

ADAM cleavage was only modestly impaired in numerous Inpp5b-null males and varied between individual animals.
Title: Multivariate analysis of male reproductive function in Inpp5b-/- mice reveals heterogeneity in defects in fertility, sperm-egg membrane interaction and proteolytic cleavage of sperm ADAMs.

These results indicate a functional overlap of Ocrl and Inpp5b in most cell lineages, especially in extraembryonic tissues.
Title: X-inactivation analysis of embryonic lethality in Ocrl wt/-; Inpp5b-/- mice.

72-5ptase expression promoted GLUT4 trafficking via a Rab11-dependent pathway but not by Rab5-mediated endocytosis. Therefore, endogenous PtdIns(3)P at the plasma membrane promotes GLUT4 translocation.
Title: Phosphatidylinositol 3-phosphate [PtdIns3P] is generated at the plasma membrane by an inositol polyphosphate 5-phosphatase: endogenous PtdIns3P can promote GLUT4 translocation to the plasma membrane.

The following Inpp5b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Inpp5b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu33386	XM_006502809.3 Latest version!	Mus musculus inositol polyphosphate-5-phosphatase B (Inpp5b), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu68019	NM_008385.4 Latest version!	Mus musculus inositol polyphosphate-5-phosphatase B (Inpp5b), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$580.30 $829.00
OMu33382	XM_006502805.2 Latest version!	Mus musculus inositol polyphosphate-5-phosphatase B (Inpp5b), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OMu33382	XM_006502804.3 Latest version!	Mus musculus inositol polyphosphate-5-phosphatase B (Inpp5b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OMu68018	XM_011240450.2 Latest version!	Mus musculus inositol polyphosphate-5-phosphatase B (Inpp5b), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Inpp5b ( XM_006502809.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006502872.1 Mus musculus inositol polyphosphate-5-phosphatase B (Inpp5b), transcript variant X6, mRNA.

Price & Availability↑

CloneID	OMu33386
Clone ID Related Accession (Same CDS sequence)	XM_006502809.3
Accession Version	XM_006502809.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1566bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006502809.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCAGT CTGTGGCAAT CCAGGAGACC CTGGTTGAGG GGGAATACTG CGTCATCCAG 
GCAGTCCAAG GTGTGCTGTG TAAGGGAGAT AGCCGGCAGA GCCGCCTGCT CGGGCTGGTG 
AGGTACCGGC TGGAAAATGA CGCCCAGGAG CATGCTCTCT TCCTGTATAC ACACCGGAGG 
ATGGCCATCA CAGGAGACGA TGTATCTCTG GACCAGATAG TGCCACTCTC AAAAGATTTT 
ATGCTGGAAG AAGTGTCCCC AGATGGTGAA CTCTACATCC TTGGCTCTGA TGTGACAGTA 
CAATTGAACA CAGCTGAACT CAAGCTTGTA TTCCAACTTC CCTTTGGTTC ACACACCAGA 
ACGTTCCTCC AGGAAGTGGC CAGAGCCTGT CCAGGTTTCG ACCCTGAGAC GCGGGATCCC 
GAGTTCGAGT GGCTGTCAAG ACACACATGC GCGGAGCCCG ATGCCGAGTC GCCGAAACCG 
CGCGAGTGGA ATTCGGACCC GGGTACCCGG AGTGGGTTCG CGCCCATTGG AGGAAGCAGG 
CATCAGTCTC GGAATGCACG GCGAGGATTG GAGGATGTCT TGCCTAGGGG CCCTGGCTAC 
ATTCTGCTTT GGGGCGGAGC CGCTGAGGAG CCGGAATTTC TATTGGCGGA GGAGATGCAT 
GAGGGCGGGC CTGTGAGAGG ACGGAGACCG CTCGCCGGGC GGCGGGATGA AGCGCTTGAG 
GAAGCAGACT GGGAAATGTC GGCAGGCGGC GGCTCTCGGG AGCGCGACTG TGCAGGCGTT 
TCTAATGTGG ACAGCTCGAG GCCAAATGGG AGGGGCCCGG ACCAACCCTC CGGAGCCAGG 
TGTCCGGAGA AACCAGAAAA CTCTCTCACA AGACAGAATA AATCTAAGTC TGACATGTCT 
GAAAAGGTTC GCTCCGCCAC AGTCACAGTA TCGGACAAGG CTCACATTTT ATCCGTGCAG 
AAGTTTGGGC TTCGAGACAC AATCGTGAGA TCACACCTCG TGCAGAAGGA AGAGAATTAT 
ACCTACATCC AGAACTTCAG GTTTTTTGTG GGAACCTACA ATGTGAACGG ACAGTCCCCC 
AAAGAATGTC TCCGGCCCTG GCTGAGCCAC AGCGCCCTGG CCCCCGACGT GTACTGTGTA 
GGGTTCCAGG AGCTCGACCT GAGTAAGGAA GCCTTCTTCT TTCACGATAC CCCAAAGGAG 
GAAGAGTGGT TTAAGGCCGT GTCAGAAAGC CTTCACCCAG ACGCCAAGTA CGCAAAGGTG 
AAGTTCGTCC GACTGGTTGG GATTATGTTG CTGCTGTACG TCAAACAGGA ACATGCAGCC 
TATATCTCAG AAGTGGAAGC TGAGACCGTA GGGACAGGAA TCATGGGAAG GATGGGTAAC 
AAAGGAGGAG TGGCGATCAG GTTCCAGCTG CACAACACCA GCATCTGCGT TGTCAATTCC 
CATCTGGCAG CCCACACAGA GGAGTACGAG AGGAGGAACC AAGACTACAG AGACATTTGT 
TCTCGAATGC AGTTCCCTCA GGTGGATCCG AGCCAACCCC CTCTCACCAT TAACAAGCAT 
GACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006502872.1
CDS	161..1726
Translation	MDQSVAIQETLVEGEYCVIQAVQGVLCKGDSRQSRLLGLVRYRLENDAQEHALFLYTHRRMAITGDDVSLDQIVPLSKDFMLEEVSPDGELYILGSDVTVQLNTAELKLVFQLPFGSHTRTFLQEVARACPGFDPETRDPEFEWLSRHTCAEPDAESPKPREWNSDPGTRSGFAPIGGSRHQSRNARRGLEDVLPRGPGYILLWGGAAEEPEFLLAEEMHEGGPVRGRRPLAGRRDEALEEADWEMSAGGGSRERDCAGVSNVDSSRPNGRGPDQPSGARCPEKPENSLTRQNKSKSDMSEKVRSATVTVSDKAHILSVQKFGLRDTIVRSHLVQKEENYTYIQNFRFFVGTYNVNGQSPKECLRPWLSHSALAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSESLHPDAKYAKVKFVRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQLHNTSICVVNSHLAAHTEEYERRNQDYRDICSRMQFPQVDPSQPPLTINKHD

Target ORF information:

RefSeq Version	XM_006502809.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus inositol polyphosphate-5-phosphatase B (Inpp5b), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006502809.3

ORF Insert Sequence:

ATGGACCAGT CTGTGGCAAT CCAGGAGACC CTGGTTGAGG GGGAATACTG CGTCATCCAG 
GCAGTCCAAG GTGTGCTGTG TAAGGGAGAT AGCCGGCAGA GCCGCCTGCT CGGGCTGGTG 
AGGTACCGGC TGGAAAATGA CGCCCAGGAG CATGCTCTCT TCCTGTATAC ACACCGGAGG 
ATGGCCATCA CAGGAGACGA TGTATCTCTG GACCAGATAG TGCCACTCTC AAAAGATTTT 
ATGCTGGAAG AAGTGTCCCC AGATGGTGAA CTCTACATCC TTGGCTCTGA TGTGACAGTA 
CAATTGAACA CAGCTGAACT CAAGCTTGTA TTCCAACTTC CCTTTGGTTC ACACACCAGA 
ACGTTCCTCC AGGAAGTGGC CAGAGCCTGT CCAGGTTTCG ACCCTGAGAC GCGGGATCCC 
GAGTTCGAGT GGCTGTCAAG ACACACATGC GCGGAGCCCG ATGCCGAGTC GCCGAAACCG 
CGCGAGTGGA ATTCGGACCC GGGTACCCGG AGTGGGTTCG CGCCCATTGG AGGAAGCAGG 
CATCAGTCTC GGAATGCACG GCGAGGATTG GAGGATGTCT TGCCTAGGGG CCCTGGCTAC 
ATTCTGCTTT GGGGCGGAGC CGCTGAGGAG CCGGAATTTC TATTGGCGGA GGAGATGCAT 
GAGGGCGGGC CTGTGAGAGG ACGGAGACCG CTCGCCGGGC GGCGGGATGA AGCGCTTGAG 
GAAGCAGACT GGGAAATGTC GGCAGGCGGC GGCTCTCGGG AGCGCGACTG TGCAGGCGTT 
TCTAATGTGG ACAGCTCGAG GCCAAATGGG AGGGGCCCGG ACCAACCCTC CGGAGCCAGG 
TGTCCGGAGA AACCAGAAAA CTCTCTCACA AGACAGAATA AATCTAAGTC TGACATGTCT 
GAAAAGGTTC GCTCCGCCAC AGTCACAGTA TCGGACAAGG CTCACATTTT ATCCGTGCAG 
AAGTTTGGGC TTCGAGACAC AATCGTGAGA TCACACCTCG TGCAGAAGGA AGAGAATTAT 
ACCTACATCC AGAACTTCAG GTTTTTTGTG GGAACCTACA ATGTGAACGG ACAGTCCCCC 
AAAGAATGTC TCCGGCCCTG GCTGAGCCAC AGCGCCCTGG CCCCCGACGT GTACTGTGTA 
GGGTTCCAGG AGCTCGACCT GAGTAAGGAA GCCTTCTTCT TTCACGATAC CCCAAAGGAG 
GAAGAGTGGT TTAAGGCCGT GTCAGAAAGC CTTCACCCAG ACGCCAAGTA CGCAAAGGTG 
AAGTTCGTCC GACTGGTTGG GATTATGTTG CTGCTGTACG TCAAACAGGA ACATGCAGCC 
TATATCTCAG AAGTGGAAGC TGAGACCGTA GGGACAGGAA TCATGGGAAG GATGGGTAAC 
AAAGGAGGAG TGGCGATCAG GTTCCAGCTG CACAACACCA GCATCTGCGT TGTCAATTCC 
CATCTGGCAG CCCACACAGA GGAGTACGAG AGGAGGAACC AAGACTACAG AGACATTTGT 
TCTCGAATGC AGTTCCCTCA GGTGGATCCG AGCCAACCCC CTCTCACCAT TAACAAGCAT 
GACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Inpp5b ( NM_008385.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032411.3 Mus musculus inositol polyphosphate-5-phosphatase B (Inpp5b), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu68019
Clone ID Related Accession (Same CDS sequence)	NM_008385.4
Accession Version	NM_008385.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2982bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-10
Organism	Mus musculus(house mouse)
Product	type II inositol 1,4,5-trisphosphate 5-phosphatase precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BY778295.1, AK163187.1, BU701664.1, CK390048.1, CA315937.1, CA320508.1, BU610644.1, BU921160.1, BE996479.1, DV654857.1, BG802289.1 and BE988792.1. On Nov 8, 2014 this sequence version replaced NM_008385.3. Transcript Variant: This variant (1) represents the shorter transcript and encodes the protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGACCAGT CTGTGGCAAT CCAGGAGACC CTGGTTGAGG GGGAATACTG CGTCATCGCA 
GTCCAAGGTG TGCTGTGTAA GGGAGATAGC CGGCAGAGCC GCCTGCTCGG GCTGGTGAGG 
TACCGGCTGG AAAATGACGC CCAGGAGCAT GCTCTCTTCC TGTATACACA CCGGAGGATG 
GCCATCACAG GAGACGATGT ATCTCTGGAC CAGATAGTGC CACTCTCAAA AGATTTTATG 
CTGGAAGAAG TGTCCCCAGA TGGTGAACTC TACATCCTTG GCTCTGATGT GACAGTACAA 
TTGAACACAG CTGAACTCAA GCTTGTATTC CAACTTCCCT TTGGTTCACA CACCAGAACG 
TTCCTCCAGG AAGTGGCCAG AGCCTGTCCA GGTTTCGACC CTGAGACGCG GGATCCCGAG 
TTCGAGTGGC TGTCAAGACA CACATGCGCG GAGCCCGATG CCGAGTCGCC GAAACCGCGC 
GAGTGGAATT CGGACCCGGG TACCCGGAGT GGGTTCGCGC CCATTGGAGG AAGCAGGCAT 
CAGTCTCGGA ATGCACGGCG AGGATTGGAG GATGTCTTGC CTAGGGGCCC TGGCTACATT 
CTGCTTTGGG GCGGAGCCGC TGAGGAGCCG GAATTTCTAT TGGCGGAGGA GATGCATGAG 
GGCGGGCCTG TGAGAGGACG GAGACCGCTC GCCGGGCGGC GGGATGAAGC GCTTGAGGAA 
GCAGACTGGG AAATGTCGGC AGGCGGCGGC TCTCGGGAGC GCGACTGTGC AGGCGTTTCT 
AATGTGGACA GCTCGAGGCC AAATGGGAGG GGCCCGGACC AACCCTCCGG AGCCAGGTGT 
CCGGAGAAAC CAGAAAACTC TCTCACAAGA CAGAATAAAT CTAAGTCTGA CATGTCTGAA 
AAGGTTCGCT CCGCCACAGT CACAGTATCG GACAAGGCTC ACATTTTATC CGTGCAGAAG 
TTTGGGCTTC GAGACACAAT CGTGAGATCA CACCTCGTGC AGAAGGAAGA GAATTATACC 
TACATCCAGA ACTTCAGGTT TTTTGTGGGA ACCTACAATG TGAACGGACA GTCCCCCAAA 
GAATGTCTCC GGCCCTGGCT GAGCCACAGC GCCCTGGCCC CCGACGTGTA CTGTGTAGGG 
TTCCAGGAGC TCGACCTGAG TAAGGAAGCC TTCTTCTTTC ACGATACCCC AAAGGAGGAA 
GAGTGGTTTA AGGCCGTGTC AGAAAGCCTT CACCCAGACG CCAAGTACGC AAAGGTGAAG 
TTCGTCCGAC TGGTTGGGAT TATGTTGCTG CTGTACGTCA AACAGGAACA TGCAGCCTAT 
ATCTCAGAAG TGGAAGCTGA GACCGTAGGG ACAGGAATCA TGGGAAGGAT GGGTAACAAA 
GGAGGAGTGG CGATCAGGTT CCAGCTGCAC AACACCAGCA TCTGCGTTGT CAATTCCCAT 
CTGGCAGCCC ACACAGAGGA GTACGAGAGG AGGAACCAAG ACTACAGAGA CATTTGTTCT 
CGAATGCAGT TCCCTCAGGT GGATCCGAGC CAACCCCCTC TCACCATTAA CAAGCATGAT 
GTGATCTTGT GGCTGGGAGA CCTCAACTAC AGGATAGAAG AGCTGGATGT GGGAAAGGTG 
AAAAAGCTCG TGGAAGAGAA GGCCTTCCAA ACCCTGTATG CGCACGACCA GCTAAAAATC 
CAGGTGGCTG CCAGGACCAT CTTTGATGGC TTCACCGAGG GTGAGATTAC ATTCCAGCCT 
ACTTACAAGT ACGATACTGG CTCTGACGAC TGGGACACCA GTGAGAAGTG TCGTGCACCG 
GCCTGGTGTG ACCGAATCCT GTGGAAAGGA AAGAACATCA CTCAGCTGAG TTACCAGAGC 
CACATGGCCT TGAAGACCAG TGACCACAAG CCTGTCAGCT CAGTGTTTGA CATTGGGGTG 
AGGGTTGTCA ATGAAGAACT CTACCGGAAG ACCCTGGAGG AAATTGTCCG CTCCCTGGAT 
AAAATGGAAA ACGCCAACAT TCCTTCTGTG ACCCTCTCCA AGCGGGAGTT CTGTTTTGAG 
AATGTGAAGT ACATGCAGTT GCAAACCGAG TCCTTCACGA TTCATAATAG CCAAGTGCCC 
TGTCAGTTTG AATTCATCAA CAAGCCTGAC GAAGAGTCCT ACTGTAAGCA GTGGCTGACG 
GCCAGACCCA GCAAGGGCTT CCTCCTGCCA GATTCGCATG TTGAGATTGA ACTTGAGCTT 
TTTGTAAATA AGTCTACTGC CACAAAACTC AACTCAGGCA AGGACACGAT TGAAGACATT 
CTGGTTTTAC ACTTGGAGCG GGGAAAGGAC TACTTTCTGT CTGTGTCTGG GAACTACCTG 
CCCAGCTGCT TCGGATCTCC TATCCATACA TTGTGCTACA TGAGGGAGCC CATCTTGGAT 
CTACCACTGA AAACTGTTAG TGACCTGACG TTGATGTCAG TGCAGACTGC AGATGACAGG 
AGCCAGTTGG AGAACCCCAT GGAAATCCCC AAAGAGCTCT GGATGATGGT GGATTACCTG 
TACAGAAATG CCGTCCAGCA GGAAGATCTG TTTCAGCAGC CAGGTCTGAG GCCAGAGTTT 
GACCATATAA GGGACTGTCT AGATACTGGG ATGATCGACC AGCTCTGTGC TAACAACCAT 
TCTGTAGCCG AAGCCTTGCT GCTTTTCCTA GAGAGCCTGC CAGAGCCTGT CATCTGTTAC 
AGCGCCTACC ATAGCTGCTT GGAGTGTTCT GGCAATTACG CAGCAAGCAA GCAGATAATT 
TTAACCCTCC CCAGCTTCCA CAAAAATGTC TTCAACTACT TGATGGCGTT TTTGCAAGAA 
CTGCTGAAAA ATTCAGCAAA CAATCATTTG GATGAGAATA TTCTAGCTAG CATATTTGGC 
AGCTTACTGC TCCGGAACCC AGCTCGTCAC CAAAAGCTTG ACATGGCGGA AAAGAAGAAG 
GCCCAAGAGT TTATTCACCA GTTCCTCTGC GGTCCACTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032411.3
CDS	138..3119
Translation	MDQSVAIQETLVEGEYCVIAVQGVLCKGDSRQSRLLGLVRYRLENDAQEHALFLYTHRRMAITGDDVSLDQIVPLSKDFMLEEVSPDGELYILGSDVTVQLNTAELKLVFQLPFGSHTRTFLQEVARACPGFDPETRDPEFEWLSRHTCAEPDAESPKPREWNSDPGTRSGFAPIGGSRHQSRNARRGLEDVLPRGPGYILLWGGAAEEPEFLLAEEMHEGGPVRGRRPLAGRRDEALEEADWEMSAGGGSRERDCAGVSNVDSSRPNGRGPDQPSGARCPEKPENSLTRQNKSKSDMSEKVRSATVTVSDKAHILSVQKFGLRDTIVRSHLVQKEENYTYIQNFRFFVGTYNVNGQSPKECLRPWLSHSALAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSESLHPDAKYAKVKFVRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQLHNTSICVVNSHLAAHTEEYERRNQDYRDICSRMQFPQVDPSQPPLTINKHDVILWLGDLNYRIEELDVGKVKKLVEEKAFQTLYAHDQLKIQVAARTIFDGFTEGEITFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGVRVVNEELYRKTLEEIVRSLDKMENANIPSVTLSKREFCFENVKYMQLQTESFTIHNSQVPCQFEFINKPDEESYCKQWLTARPSKGFLLPDSHVEIELELFVNKSTATKLNSGKDTIEDILVLHLERGKDYFLSVSGNYLPSCFGSPIHTLCYMREPILDLPLKTVSDLTLMSVQTADDRSQLENPMEIPKELWMMVDYLYRNAVQQEDLFQQPGLRPEFDHIRDCLDTGMIDQLCANNHSVAEALLLFLESLPEPVICYSAYHSCLECSGNYAASKQIILTLPSFHKNVFNYLMAFLQELLKNSANNHLDENILASIFGSLLLRNPARHQKLDMAEKKKAQEFIHQFLCGPL

Target ORF information:

RefSeq Version	NM_008385.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus inositol polyphosphate-5-phosphatase B (Inpp5b), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008385.4

ORF Insert Sequence:

ATGGACCAGT CTGTGGCAAT CCAGGAGACC CTGGTTGAGG GGGAATACTG CGTCATCGCA 
GTCCAAGGTG TGCTGTGTAA GGGAGATAGC CGGCAGAGCC GCCTGCTCGG GCTGGTGAGG 
TACCGGCTGG AAAATGACGC CCAGGAGCAT GCTCTCTTCC TGTATACACA CCGGAGGATG 
GCCATCACAG GAGACGATGT ATCTCTGGAC CAGATAGTGC CACTCTCAAA AGATTTTATG 
CTGGAAGAAG TGTCCCCAGA TGGTGAACTC TACATCCTTG GCTCTGATGT GACAGTACAA 
TTGAACACAG CTGAACTCAA GCTTGTATTC CAACTTCCCT TTGGTTCACA CACCAGAACG 
TTCCTCCAGG AAGTGGCCAG AGCCTGTCCA GGTTTCGACC CTGAGACGCG GGATCCCGAG 
TTCGAGTGGC TGTCAAGACA CACATGCGCG GAGCCCGATG CCGAGTCGCC GAAACCGCGC 
GAGTGGAATT CGGACCCGGG TACCCGGAGT GGGTTCGCGC CCATTGGAGG AAGCAGGCAT 
CAGTCTCGGA ATGCACGGCG AGGATTGGAG GATGTCTTGC CTAGGGGCCC TGGCTACATT 
CTGCTTTGGG GCGGAGCCGC TGAGGAGCCG GAATTTCTAT TGGCGGAGGA GATGCATGAG 
GGCGGGCCTG TGAGAGGACG GAGACCGCTC GCCGGGCGGC GGGATGAAGC GCTTGAGGAA 
GCAGACTGGG AAATGTCGGC AGGCGGCGGC TCTCGGGAGC GCGACTGTGC AGGCGTTTCT 
AATGTGGACA GCTCGAGGCC AAATGGGAGG GGCCCGGACC AACCCTCCGG AGCCAGGTGT 
CCGGAGAAAC CAGAAAACTC TCTCACAAGA CAGAATAAAT CTAAGTCTGA CATGTCTGAA 
AAGGTTCGCT CCGCCACAGT CACAGTATCG GACAAGGCTC ACATTTTATC CGTGCAGAAG 
TTTGGGCTTC GAGACACAAT CGTGAGATCA CACCTCGTGC AGAAGGAAGA GAATTATACC 
TACATCCAGA ACTTCAGGTT TTTTGTGGGA ACCTACAATG TGAACGGACA GTCCCCCAAA 
GAATGTCTCC GGCCCTGGCT GAGCCACAGC GCCCTGGCCC CCGACGTGTA CTGTGTAGGG 
TTCCAGGAGC TCGACCTGAG TAAGGAAGCC TTCTTCTTTC ACGATACCCC AAAGGAGGAA 
GAGTGGTTTA AGGCCGTGTC AGAAAGCCTT CACCCAGACG CCAAGTACGC AAAGGTGAAG 
TTCGTCCGAC TGGTTGGGAT TATGTTGCTG CTGTACGTCA AACAGGAACA TGCAGCCTAT 
ATCTCAGAAG TGGAAGCTGA GACCGTAGGG ACAGGAATCA TGGGAAGGAT GGGTAACAAA 
GGAGGAGTGG CGATCAGGTT CCAGCTGCAC AACACCAGCA TCTGCGTTGT CAATTCCCAT 
CTGGCAGCCC ACACAGAGGA GTACGAGAGG AGGAACCAAG ACTACAGAGA CATTTGTTCT 
CGAATGCAGT TCCCTCAGGT GGATCCGAGC CAACCCCCTC TCACCATTAA CAAGCATGAT 
GTGATCTTGT GGCTGGGAGA CCTCAACTAC AGGATAGAAG AGCTGGATGT GGGAAAGGTG 
AAAAAGCTCG TGGAAGAGAA GGCCTTCCAA ACCCTGTATG CGCACGACCA GCTAAAAATC 
CAGGTGGCTG CCAGGACCAT CTTTGATGGC TTCACCGAGG GTGAGATTAC ATTCCAGCCT 
ACTTACAAGT ACGATACTGG CTCTGACGAC TGGGACACCA GTGAGAAGTG TCGTGCACCG 
GCCTGGTGTG ACCGAATCCT GTGGAAAGGA AAGAACATCA CTCAGCTGAG TTACCAGAGC 
CACATGGCCT TGAAGACCAG TGACCACAAG CCTGTCAGCT CAGTGTTTGA CATTGGGGTG 
AGGGTTGTCA ATGAAGAACT CTACCGGAAG ACCCTGGAGG AAATTGTCCG CTCCCTGGAT 
AAAATGGAAA ACGCCAACAT TCCTTCTGTG ACCCTCTCCA AGCGGGAGTT CTGTTTTGAG 
AATGTGAAGT ACATGCAGTT GCAAACCGAG TCCTTCACGA TTCATAATAG CCAAGTGCCC 
TGTCAGTTTG AATTCATCAA CAAGCCTGAC GAAGAGTCCT ACTGTAAGCA GTGGCTGACG 
GCCAGACCCA GCAAGGGCTT CCTCCTGCCA GATTCGCATG TTGAGATTGA ACTTGAGCTT 
TTTGTAAATA AGTCTACTGC CACAAAACTC AACTCAGGCA AGGACACGAT TGAAGACATT 
CTGGTTTTAC ACTTGGAGCG GGGAAAGGAC TACTTTCTGT CTGTGTCTGG GAACTACCTG 
CCCAGCTGCT TCGGATCTCC TATCCATACA TTGTGCTACA TGAGGGAGCC CATCTTGGAT 
CTACCACTGA AAACTGTTAG TGACCTGACG TTGATGTCAG TGCAGACTGC AGATGACAGG 
AGCCAGTTGG AGAACCCCAT GGAAATCCCC AAAGAGCTCT GGATGATGGT GGATTACCTG 
TACAGAAATG CCGTCCAGCA GGAAGATCTG TTTCAGCAGC CAGGTCTGAG GCCAGAGTTT 
GACCATATAA GGGACTGTCT AGATACTGGG ATGATCGACC AGCTCTGTGC TAACAACCAT 
TCTGTAGCCG AAGCCTTGCT GCTTTTCCTA GAGAGCCTGC CAGAGCCTGT CATCTGTTAC 
AGCGCCTACC ATAGCTGCTT GGAGTGTTCT GGCAATTACG CAGCAAGCAA GCAGATAATT 
TTAACCCTCC CCAGCTTCCA CAAAAATGTC TTCAACTACT TGATGGCGTT TTTGCAAGAA 
CTGCTGAAAA ATTCAGCAAA CAATCATTTG GATGAGAATA TTCTAGCTAG CATATTTGGC 
AGCTTACTGC TCCGGAACCC AGCTCGTCAC CAAAAGCTTG ACATGGCGGA AAAGAAGAAG 
GCCCAAGAGT TTATTCACCA GTTCCTCTGC GGTCCACTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Inpp5b ( XM_006502804.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006502867.1 Mus musculus inositol polyphosphate-5-phosphatase B (Inpp5b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu33382
Clone ID Related Accession (Same CDS sequence)	XM_006502804.3 , XM_006502805.2
Accession Version	XM_006502804.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2985bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006502804.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCAGT CTGTGGCAAT CCAGGAGACC CTGGTTGAGG GGGAATACTG CGTCATCCAG 
GCAGTCCAAG GTGTGCTGTG TAAGGGAGAT AGCCGGCAGA GCCGCCTGCT CGGGCTGGTG 
AGGTACCGGC TGGAAAATGA CGCCCAGGAG CATGCTCTCT TCCTGTATAC ACACCGGAGG 
ATGGCCATCA CAGGAGACGA TGTATCTCTG GACCAGATAG TGCCACTCTC AAAAGATTTT 
ATGCTGGAAG AAGTGTCCCC AGATGGTGAA CTCTACATCC TTGGCTCTGA TGTGACAGTA 
CAATTGAACA CAGCTGAACT CAAGCTTGTA TTCCAACTTC CCTTTGGTTC ACACACCAGA 
ACGTTCCTCC AGGAAGTGGC CAGAGCCTGT CCAGGTTTCG ACCCTGAGAC GCGGGATCCC 
GAGTTCGAGT GGCTGTCAAG ACACACATGC GCGGAGCCCG ATGCCGAGTC GCCGAAACCG 
CGCGAGTGGA ATTCGGACCC GGGTACCCGG AGTGGGTTCG CGCCCATTGG AGGAAGCAGG 
CATCAGTCTC GGAATGCACG GCGAGGATTG GAGGATGTCT TGCCTAGGGG CCCTGGCTAC 
ATTCTGCTTT GGGGCGGAGC CGCTGAGGAG CCGGAATTTC TATTGGCGGA GGAGATGCAT 
GAGGGCGGGC CTGTGAGAGG ACGGAGACCG CTCGCCGGGC GGCGGGATGA AGCGCTTGAG 
GAAGCAGACT GGGAAATGTC GGCAGGCGGC GGCTCTCGGG AGCGCGACTG TGCAGGCGTT 
TCTAATGTGG ACAGCTCGAG GCCAAATGGG AGGGGCCCGG ACCAACCCTC CGGAGCCAGG 
TGTCCGGAGA AACCAGAAAA CTCTCTCACA AGACAGAATA AATCTAAGTC TGACATGTCT 
GAAAAGGTTC GCTCCGCCAC AGTCACAGTA TCGGACAAGG CTCACATTTT ATCCGTGCAG 
AAGTTTGGGC TTCGAGACAC AATCGTGAGA TCACACCTCG TGCAGAAGGA AGAGAATTAT 
ACCTACATCC AGAACTTCAG GTTTTTTGTG GGAACCTACA ATGTGAACGG ACAGTCCCCC 
AAAGAATGTC TCCGGCCCTG GCTGAGCCAC AGCGCCCTGG CCCCCGACGT GTACTGTGTA 
GGGTTCCAGG AGCTCGACCT GAGTAAGGAA GCCTTCTTCT TTCACGATAC CCCAAAGGAG 
GAAGAGTGGT TTAAGGCCGT GTCAGAAAGC CTTCACCCAG ACGCCAAGTA CGCAAAGGTG 
AAGTTCGTCC GACTGGTTGG GATTATGTTG CTGCTGTACG TCAAACAGGA ACATGCAGCC 
TATATCTCAG AAGTGGAAGC TGAGACCGTA GGGACAGGAA TCATGGGAAG GATGGGTAAC 
AAAGGAGGAG TGGCGATCAG GTTCCAGCTG CACAACACCA GCATCTGCGT TGTCAATTCC 
CATCTGGCAG CCCACACAGA GGAGTACGAG AGGAGGAACC AAGACTACAG AGACATTTGT 
TCTCGAATGC AGTTCCCTCA GGTGGATCCG AGCCAACCCC CTCTCACCAT TAACAAGCAT 
GATGTGATCT TGTGGCTGGG AGACCTCAAC TACAGGATAG AAGAGCTGGA TGTGGGAAAG 
GTGAAAAAGC TCGTGGAAGA GAAGGCCTTC CAAACCCTGT ATGCGCACGA CCAGCTAAAA 
ATCCAGGTGG CTGCCAGGAC CATCTTTGAT GGCTTCACCG AGGGTGAGAT TACATTCCAG 
CCTACTTACA AGTACGATAC TGGCTCTGAC GACTGGGACA CCAGTGAGAA GTGTCGTGCA 
CCGGCCTGGT GTGACCGAAT CCTGTGGAAA GGAAAGAACA TCACTCAGCT GAGTTACCAG 
AGCCACATGG CCTTGAAGAC CAGTGACCAC AAGCCTGTCA GCTCAGTGTT TGACATTGGG 
GTGAGGGTTG TCAATGAAGA ACTCTACCGG AAGACCCTGG AGGAAATTGT CCGCTCCCTG 
GATAAAATGG AAAACGCCAA CATTCCTTCT GTGACCCTCT CCAAGCGGGA GTTCTGTTTT 
GAGAATGTGA AGTACATGCA GTTGCAAACC GAGTCCTTCA CGATTCATAA TAGCCAAGTG 
CCCTGTCAGT TTGAATTCAT CAACAAGCCT GACGAAGAGT CCTACTGTAA GCAGTGGCTG 
ACGGCCAGAC CCAGCAAGGG CTTCCTCCTG CCAGATTCGC ATGTTGAGAT TGAACTTGAG 
CTTTTTGTAA ATAAGTCTAC TGCCACAAAA CTCAACTCAG GCAAGGACAC GATTGAAGAC 
ATTCTGGTTT TACACTTGGA GCGGGGAAAG GACTACTTTC TGTCTGTGTC TGGGAACTAC 
CTGCCCAGCT GCTTCGGATC TCCTATCCAT ACATTGTGCT ACATGAGGGA GCCCATCTTG 
GATCTACCAC TGAAAACTGT TAGTGACCTG ACGTTGATGT CAGTGCAGAC TGCAGATGAC 
AGGAGCCAGT TGGAGAACCC CATGGAAATC CCCAAAGAGC TCTGGATGAT GGTGGATTAC 
CTGTACAGAA ATGCCGTCCA GCAGGAAGAT CTGTTTCAGC AGCCAGGTCT GAGGCCAGAG 
TTTGACCATA TAAGGGACTG TCTAGATACT GGGATGATCG ACCAGCTCTG TGCTAACAAC 
CATTCTGTAG CCGAAGCCTT GCTGCTTTTC CTAGAGAGCC TGCCAGAGCC TGTCATCTGT 
TACAGCGCCT ACCATAGCTG CTTGGAGTGT TCTGGCAATT ACGCAGCAAG CAAGCAGATA 
ATTTTAACCC TCCCCAGCTT CCACAAAAAT GTCTTCAACT ACTTGATGGC GTTTTTGCAA 
GAACTGCTGA AAAATTCAGC AAACAATCAT TTGGATGAGA ATATTCTAGC TAGCATATTT 
GGCAGCTTAC TGCTCCGGAA CCCAGCTCGT CACCAAAAGC TTGACATGGC GGAAAAGAAG 
AAGGCCCAAG AGTTTATTCA CCAGTTCCTC TGCGGTCCAC TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006502867.1
CDS	161..3145
Translation	MDQSVAIQETLVEGEYCVIQAVQGVLCKGDSRQSRLLGLVRYRLENDAQEHALFLYTHRRMAITGDDVSLDQIVPLSKDFMLEEVSPDGELYILGSDVTVQLNTAELKLVFQLPFGSHTRTFLQEVARACPGFDPETRDPEFEWLSRHTCAEPDAESPKPREWNSDPGTRSGFAPIGGSRHQSRNARRGLEDVLPRGPGYILLWGGAAEEPEFLLAEEMHEGGPVRGRRPLAGRRDEALEEADWEMSAGGGSRERDCAGVSNVDSSRPNGRGPDQPSGARCPEKPENSLTRQNKSKSDMSEKVRSATVTVSDKAHILSVQKFGLRDTIVRSHLVQKEENYTYIQNFRFFVGTYNVNGQSPKECLRPWLSHSALAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSESLHPDAKYAKVKFVRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQLHNTSICVVNSHLAAHTEEYERRNQDYRDICSRMQFPQVDPSQPPLTINKHDVILWLGDLNYRIEELDVGKVKKLVEEKAFQTLYAHDQLKIQVAARTIFDGFTEGEITFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGVRVVNEELYRKTLEEIVRSLDKMENANIPSVTLSKREFCFENVKYMQLQTESFTIHNSQVPCQFEFINKPDEESYCKQWLTARPSKGFLLPDSHVEIELELFVNKSTATKLNSGKDTIEDILVLHLERGKDYFLSVSGNYLPSCFGSPIHTLCYMREPILDLPLKTVSDLTLMSVQTADDRSQLENPMEIPKELWMMVDYLYRNAVQQEDLFQQPGLRPEFDHIRDCLDTGMIDQLCANNHSVAEALLLFLESLPEPVICYSAYHSCLECSGNYAASKQIILTLPSFHKNVFNYLMAFLQELLKNSANNHLDENILASIFGSLLLRNPARHQKLDMAEKKKAQEFIHQFLCGPL

Target ORF information:

RefSeq Version	XM_006502804.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus inositol polyphosphate-5-phosphatase B (Inpp5b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006502804.3

ORF Insert Sequence:

ATGGACCAGT CTGTGGCAAT CCAGGAGACC CTGGTTGAGG GGGAATACTG CGTCATCCAG 
GCAGTCCAAG GTGTGCTGTG TAAGGGAGAT AGCCGGCAGA GCCGCCTGCT CGGGCTGGTG 
AGGTACCGGC TGGAAAATGA CGCCCAGGAG CATGCTCTCT TCCTGTATAC ACACCGGAGG 
ATGGCCATCA CAGGAGACGA TGTATCTCTG GACCAGATAG TGCCACTCTC AAAAGATTTT 
ATGCTGGAAG AAGTGTCCCC AGATGGTGAA CTCTACATCC TTGGCTCTGA TGTGACAGTA 
CAATTGAACA CAGCTGAACT CAAGCTTGTA TTCCAACTTC CCTTTGGTTC ACACACCAGA 
ACGTTCCTCC AGGAAGTGGC CAGAGCCTGT CCAGGTTTCG ACCCTGAGAC GCGGGATCCC 
GAGTTCGAGT GGCTGTCAAG ACACACATGC GCGGAGCCCG ATGCCGAGTC GCCGAAACCG 
CGCGAGTGGA ATTCGGACCC GGGTACCCGG AGTGGGTTCG CGCCCATTGG AGGAAGCAGG 
CATCAGTCTC GGAATGCACG GCGAGGATTG GAGGATGTCT TGCCTAGGGG CCCTGGCTAC 
ATTCTGCTTT GGGGCGGAGC CGCTGAGGAG CCGGAATTTC TATTGGCGGA GGAGATGCAT 
GAGGGCGGGC CTGTGAGAGG ACGGAGACCG CTCGCCGGGC GGCGGGATGA AGCGCTTGAG 
GAAGCAGACT GGGAAATGTC GGCAGGCGGC GGCTCTCGGG AGCGCGACTG TGCAGGCGTT 
TCTAATGTGG ACAGCTCGAG GCCAAATGGG AGGGGCCCGG ACCAACCCTC CGGAGCCAGG 
TGTCCGGAGA AACCAGAAAA CTCTCTCACA AGACAGAATA AATCTAAGTC TGACATGTCT 
GAAAAGGTTC GCTCCGCCAC AGTCACAGTA TCGGACAAGG CTCACATTTT ATCCGTGCAG 
AAGTTTGGGC TTCGAGACAC AATCGTGAGA TCACACCTCG TGCAGAAGGA AGAGAATTAT 
ACCTACATCC AGAACTTCAG GTTTTTTGTG GGAACCTACA ATGTGAACGG ACAGTCCCCC 
AAAGAATGTC TCCGGCCCTG GCTGAGCCAC AGCGCCCTGG CCCCCGACGT GTACTGTGTA 
GGGTTCCAGG AGCTCGACCT GAGTAAGGAA GCCTTCTTCT TTCACGATAC CCCAAAGGAG 
GAAGAGTGGT TTAAGGCCGT GTCAGAAAGC CTTCACCCAG ACGCCAAGTA CGCAAAGGTG 
AAGTTCGTCC GACTGGTTGG GATTATGTTG CTGCTGTACG TCAAACAGGA ACATGCAGCC 
TATATCTCAG AAGTGGAAGC TGAGACCGTA GGGACAGGAA TCATGGGAAG GATGGGTAAC 
AAAGGAGGAG TGGCGATCAG GTTCCAGCTG CACAACACCA GCATCTGCGT TGTCAATTCC 
CATCTGGCAG CCCACACAGA GGAGTACGAG AGGAGGAACC AAGACTACAG AGACATTTGT 
TCTCGAATGC AGTTCCCTCA GGTGGATCCG AGCCAACCCC CTCTCACCAT TAACAAGCAT 
GATGTGATCT TGTGGCTGGG AGACCTCAAC TACAGGATAG AAGAGCTGGA TGTGGGAAAG 
GTGAAAAAGC TCGTGGAAGA GAAGGCCTTC CAAACCCTGT ATGCGCACGA CCAGCTAAAA 
ATCCAGGTGG CTGCCAGGAC CATCTTTGAT GGCTTCACCG AGGGTGAGAT TACATTCCAG 
CCTACTTACA AGTACGATAC TGGCTCTGAC GACTGGGACA CCAGTGAGAA GTGTCGTGCA 
CCGGCCTGGT GTGACCGAAT CCTGTGGAAA GGAAAGAACA TCACTCAGCT GAGTTACCAG 
AGCCACATGG CCTTGAAGAC CAGTGACCAC AAGCCTGTCA GCTCAGTGTT TGACATTGGG 
GTGAGGGTTG TCAATGAAGA ACTCTACCGG AAGACCCTGG AGGAAATTGT CCGCTCCCTG 
GATAAAATGG AAAACGCCAA CATTCCTTCT GTGACCCTCT CCAAGCGGGA GTTCTGTTTT 
GAGAATGTGA AGTACATGCA GTTGCAAACC GAGTCCTTCA CGATTCATAA TAGCCAAGTG 
CCCTGTCAGT TTGAATTCAT CAACAAGCCT GACGAAGAGT CCTACTGTAA GCAGTGGCTG 
ACGGCCAGAC CCAGCAAGGG CTTCCTCCTG CCAGATTCGC ATGTTGAGAT TGAACTTGAG 
CTTTTTGTAA ATAAGTCTAC TGCCACAAAA CTCAACTCAG GCAAGGACAC GATTGAAGAC 
ATTCTGGTTT TACACTTGGA GCGGGGAAAG GACTACTTTC TGTCTGTGTC TGGGAACTAC 
CTGCCCAGCT GCTTCGGATC TCCTATCCAT ACATTGTGCT ACATGAGGGA GCCCATCTTG 
GATCTACCAC TGAAAACTGT TAGTGACCTG ACGTTGATGT CAGTGCAGAC TGCAGATGAC 
AGGAGCCAGT TGGAGAACCC CATGGAAATC CCCAAAGAGC TCTGGATGAT GGTGGATTAC 
CTGTACAGAA ATGCCGTCCA GCAGGAAGAT CTGTTTCAGC AGCCAGGTCT GAGGCCAGAG 
TTTGACCATA TAAGGGACTG TCTAGATACT GGGATGATCG ACCAGCTCTG TGCTAACAAC 
CATTCTGTAG CCGAAGCCTT GCTGCTTTTC CTAGAGAGCC TGCCAGAGCC TGTCATCTGT 
TACAGCGCCT ACCATAGCTG CTTGGAGTGT TCTGGCAATT ACGCAGCAAG CAAGCAGATA 
ATTTTAACCC TCCCCAGCTT CCACAAAAAT GTCTTCAACT ACTTGATGGC GTTTTTGCAA 
GAACTGCTGA AAAATTCAGC AAACAATCAT TTGGATGAGA ATATTCTAGC TAGCATATTT 
GGCAGCTTAC TGCTCCGGAA CCCAGCTCGT CACCAAAAGC TTGACATGGC GGAAAAGAAG 
AAGGCCCAAG AGTTTATTCA CCAGTTCCTC TGCGGTCCAC TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Inpp5b ( XM_006502805.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006502868.1 Mus musculus inositol polyphosphate-5-phosphatase B (Inpp5b), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu33382
Clone ID Related Accession (Same CDS sequence)	XM_006502804.3 , XM_006502805.2
Accession Version	XM_006502805.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2985bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006502805.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCAGT CTGTGGCAAT CCAGGAGACC CTGGTTGAGG GGGAATACTG CGTCATCCAG 
GCAGTCCAAG GTGTGCTGTG TAAGGGAGAT AGCCGGCAGA GCCGCCTGCT CGGGCTGGTG 
AGGTACCGGC TGGAAAATGA CGCCCAGGAG CATGCTCTCT TCCTGTATAC ACACCGGAGG 
ATGGCCATCA CAGGAGACGA TGTATCTCTG GACCAGATAG TGCCACTCTC AAAAGATTTT 
ATGCTGGAAG AAGTGTCCCC AGATGGTGAA CTCTACATCC TTGGCTCTGA TGTGACAGTA 
CAATTGAACA CAGCTGAACT CAAGCTTGTA TTCCAACTTC CCTTTGGTTC ACACACCAGA 
ACGTTCCTCC AGGAAGTGGC CAGAGCCTGT CCAGGTTTCG ACCCTGAGAC GCGGGATCCC 
GAGTTCGAGT GGCTGTCAAG ACACACATGC GCGGAGCCCG ATGCCGAGTC GCCGAAACCG 
CGCGAGTGGA ATTCGGACCC GGGTACCCGG AGTGGGTTCG CGCCCATTGG AGGAAGCAGG 
CATCAGTCTC GGAATGCACG GCGAGGATTG GAGGATGTCT TGCCTAGGGG CCCTGGCTAC 
ATTCTGCTTT GGGGCGGAGC CGCTGAGGAG CCGGAATTTC TATTGGCGGA GGAGATGCAT 
GAGGGCGGGC CTGTGAGAGG ACGGAGACCG CTCGCCGGGC GGCGGGATGA AGCGCTTGAG 
GAAGCAGACT GGGAAATGTC GGCAGGCGGC GGCTCTCGGG AGCGCGACTG TGCAGGCGTT 
TCTAATGTGG ACAGCTCGAG GCCAAATGGG AGGGGCCCGG ACCAACCCTC CGGAGCCAGG 
TGTCCGGAGA AACCAGAAAA CTCTCTCACA AGACAGAATA AATCTAAGTC TGACATGTCT 
GAAAAGGTTC GCTCCGCCAC AGTCACAGTA TCGGACAAGG CTCACATTTT ATCCGTGCAG 
AAGTTTGGGC TTCGAGACAC AATCGTGAGA TCACACCTCG TGCAGAAGGA AGAGAATTAT 
ACCTACATCC AGAACTTCAG GTTTTTTGTG GGAACCTACA ATGTGAACGG ACAGTCCCCC 
AAAGAATGTC TCCGGCCCTG GCTGAGCCAC AGCGCCCTGG CCCCCGACGT GTACTGTGTA 
GGGTTCCAGG AGCTCGACCT GAGTAAGGAA GCCTTCTTCT TTCACGATAC CCCAAAGGAG 
GAAGAGTGGT TTAAGGCCGT GTCAGAAAGC CTTCACCCAG ACGCCAAGTA CGCAAAGGTG 
AAGTTCGTCC GACTGGTTGG GATTATGTTG CTGCTGTACG TCAAACAGGA ACATGCAGCC 
TATATCTCAG AAGTGGAAGC TGAGACCGTA GGGACAGGAA TCATGGGAAG GATGGGTAAC 
AAAGGAGGAG TGGCGATCAG GTTCCAGCTG CACAACACCA GCATCTGCGT TGTCAATTCC 
CATCTGGCAG CCCACACAGA GGAGTACGAG AGGAGGAACC AAGACTACAG AGACATTTGT 
TCTCGAATGC AGTTCCCTCA GGTGGATCCG AGCCAACCCC CTCTCACCAT TAACAAGCAT 
GATGTGATCT TGTGGCTGGG AGACCTCAAC TACAGGATAG AAGAGCTGGA TGTGGGAAAG 
GTGAAAAAGC TCGTGGAAGA GAAGGCCTTC CAAACCCTGT ATGCGCACGA CCAGCTAAAA 
ATCCAGGTGG CTGCCAGGAC CATCTTTGAT GGCTTCACCG AGGGTGAGAT TACATTCCAG 
CCTACTTACA AGTACGATAC TGGCTCTGAC GACTGGGACA CCAGTGAGAA GTGTCGTGCA 
CCGGCCTGGT GTGACCGAAT CCTGTGGAAA GGAAAGAACA TCACTCAGCT GAGTTACCAG 
AGCCACATGG CCTTGAAGAC CAGTGACCAC AAGCCTGTCA GCTCAGTGTT TGACATTGGG 
GTGAGGGTTG TCAATGAAGA ACTCTACCGG AAGACCCTGG AGGAAATTGT CCGCTCCCTG 
GATAAAATGG AAAACGCCAA CATTCCTTCT GTGACCCTCT CCAAGCGGGA GTTCTGTTTT 
GAGAATGTGA AGTACATGCA GTTGCAAACC GAGTCCTTCA CGATTCATAA TAGCCAAGTG 
CCCTGTCAGT TTGAATTCAT CAACAAGCCT GACGAAGAGT CCTACTGTAA GCAGTGGCTG 
ACGGCCAGAC CCAGCAAGGG CTTCCTCCTG CCAGATTCGC ATGTTGAGAT TGAACTTGAG 
CTTTTTGTAA ATAAGTCTAC TGCCACAAAA CTCAACTCAG GCAAGGACAC GATTGAAGAC 
ATTCTGGTTT TACACTTGGA GCGGGGAAAG GACTACTTTC TGTCTGTGTC TGGGAACTAC 
CTGCCCAGCT GCTTCGGATC TCCTATCCAT ACATTGTGCT ACATGAGGGA GCCCATCTTG 
GATCTACCAC TGAAAACTGT TAGTGACCTG ACGTTGATGT CAGTGCAGAC TGCAGATGAC 
AGGAGCCAGT TGGAGAACCC CATGGAAATC CCCAAAGAGC TCTGGATGAT GGTGGATTAC 
CTGTACAGAA ATGCCGTCCA GCAGGAAGAT CTGTTTCAGC AGCCAGGTCT GAGGCCAGAG 
TTTGACCATA TAAGGGACTG TCTAGATACT GGGATGATCG ACCAGCTCTG TGCTAACAAC 
CATTCTGTAG CCGAAGCCTT GCTGCTTTTC CTAGAGAGCC TGCCAGAGCC TGTCATCTGT 
TACAGCGCCT ACCATAGCTG CTTGGAGTGT TCTGGCAATT ACGCAGCAAG CAAGCAGATA 
ATTTTAACCC TCCCCAGCTT CCACAAAAAT GTCTTCAACT ACTTGATGGC GTTTTTGCAA 
GAACTGCTGA AAAATTCAGC AAACAATCAT TTGGATGAGA ATATTCTAGC TAGCATATTT 
GGCAGCTTAC TGCTCCGGAA CCCAGCTCGT CACCAAAAGC TTGACATGGC GGAAAAGAAG 
AAGGCCCAAG AGTTTATTCA CCAGTTCCTC TGCGGTCCAC TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006502868.1
CDS	175..3159
Translation	MDQSVAIQETLVEGEYCVIQAVQGVLCKGDSRQSRLLGLVRYRLENDAQEHALFLYTHRRMAITGDDVSLDQIVPLSKDFMLEEVSPDGELYILGSDVTVQLNTAELKLVFQLPFGSHTRTFLQEVARACPGFDPETRDPEFEWLSRHTCAEPDAESPKPREWNSDPGTRSGFAPIGGSRHQSRNARRGLEDVLPRGPGYILLWGGAAEEPEFLLAEEMHEGGPVRGRRPLAGRRDEALEEADWEMSAGGGSRERDCAGVSNVDSSRPNGRGPDQPSGARCPEKPENSLTRQNKSKSDMSEKVRSATVTVSDKAHILSVQKFGLRDTIVRSHLVQKEENYTYIQNFRFFVGTYNVNGQSPKECLRPWLSHSALAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSESLHPDAKYAKVKFVRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQLHNTSICVVNSHLAAHTEEYERRNQDYRDICSRMQFPQVDPSQPPLTINKHDVILWLGDLNYRIEELDVGKVKKLVEEKAFQTLYAHDQLKIQVAARTIFDGFTEGEITFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGVRVVNEELYRKTLEEIVRSLDKMENANIPSVTLSKREFCFENVKYMQLQTESFTIHNSQVPCQFEFINKPDEESYCKQWLTARPSKGFLLPDSHVEIELELFVNKSTATKLNSGKDTIEDILVLHLERGKDYFLSVSGNYLPSCFGSPIHTLCYMREPILDLPLKTVSDLTLMSVQTADDRSQLENPMEIPKELWMMVDYLYRNAVQQEDLFQQPGLRPEFDHIRDCLDTGMIDQLCANNHSVAEALLLFLESLPEPVICYSAYHSCLECSGNYAASKQIILTLPSFHKNVFNYLMAFLQELLKNSANNHLDENILASIFGSLLLRNPARHQKLDMAEKKKAQEFIHQFLCGPL

Target ORF information:

RefSeq Version	XM_006502805.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus inositol polyphosphate-5-phosphatase B (Inpp5b), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006502805.2

ORF Insert Sequence:

ATGGACCAGT CTGTGGCAAT CCAGGAGACC CTGGTTGAGG GGGAATACTG CGTCATCCAG 
GCAGTCCAAG GTGTGCTGTG TAAGGGAGAT AGCCGGCAGA GCCGCCTGCT CGGGCTGGTG 
AGGTACCGGC TGGAAAATGA CGCCCAGGAG CATGCTCTCT TCCTGTATAC ACACCGGAGG 
ATGGCCATCA CAGGAGACGA TGTATCTCTG GACCAGATAG TGCCACTCTC AAAAGATTTT 
ATGCTGGAAG AAGTGTCCCC AGATGGTGAA CTCTACATCC TTGGCTCTGA TGTGACAGTA 
CAATTGAACA CAGCTGAACT CAAGCTTGTA TTCCAACTTC CCTTTGGTTC ACACACCAGA 
ACGTTCCTCC AGGAAGTGGC CAGAGCCTGT CCAGGTTTCG ACCCTGAGAC GCGGGATCCC 
GAGTTCGAGT GGCTGTCAAG ACACACATGC GCGGAGCCCG ATGCCGAGTC GCCGAAACCG 
CGCGAGTGGA ATTCGGACCC GGGTACCCGG AGTGGGTTCG CGCCCATTGG AGGAAGCAGG 
CATCAGTCTC GGAATGCACG GCGAGGATTG GAGGATGTCT TGCCTAGGGG CCCTGGCTAC 
ATTCTGCTTT GGGGCGGAGC CGCTGAGGAG CCGGAATTTC TATTGGCGGA GGAGATGCAT 
GAGGGCGGGC CTGTGAGAGG ACGGAGACCG CTCGCCGGGC GGCGGGATGA AGCGCTTGAG 
GAAGCAGACT GGGAAATGTC GGCAGGCGGC GGCTCTCGGG AGCGCGACTG TGCAGGCGTT 
TCTAATGTGG ACAGCTCGAG GCCAAATGGG AGGGGCCCGG ACCAACCCTC CGGAGCCAGG 
TGTCCGGAGA AACCAGAAAA CTCTCTCACA AGACAGAATA AATCTAAGTC TGACATGTCT 
GAAAAGGTTC GCTCCGCCAC AGTCACAGTA TCGGACAAGG CTCACATTTT ATCCGTGCAG 
AAGTTTGGGC TTCGAGACAC AATCGTGAGA TCACACCTCG TGCAGAAGGA AGAGAATTAT 
ACCTACATCC AGAACTTCAG GTTTTTTGTG GGAACCTACA ATGTGAACGG ACAGTCCCCC 
AAAGAATGTC TCCGGCCCTG GCTGAGCCAC AGCGCCCTGG CCCCCGACGT GTACTGTGTA 
GGGTTCCAGG AGCTCGACCT GAGTAAGGAA GCCTTCTTCT TTCACGATAC CCCAAAGGAG 
GAAGAGTGGT TTAAGGCCGT GTCAGAAAGC CTTCACCCAG ACGCCAAGTA CGCAAAGGTG 
AAGTTCGTCC GACTGGTTGG GATTATGTTG CTGCTGTACG TCAAACAGGA ACATGCAGCC 
TATATCTCAG AAGTGGAAGC TGAGACCGTA GGGACAGGAA TCATGGGAAG GATGGGTAAC 
AAAGGAGGAG TGGCGATCAG GTTCCAGCTG CACAACACCA GCATCTGCGT TGTCAATTCC 
CATCTGGCAG CCCACACAGA GGAGTACGAG AGGAGGAACC AAGACTACAG AGACATTTGT 
TCTCGAATGC AGTTCCCTCA GGTGGATCCG AGCCAACCCC CTCTCACCAT TAACAAGCAT 
GATGTGATCT TGTGGCTGGG AGACCTCAAC TACAGGATAG AAGAGCTGGA TGTGGGAAAG 
GTGAAAAAGC TCGTGGAAGA GAAGGCCTTC CAAACCCTGT ATGCGCACGA CCAGCTAAAA 
ATCCAGGTGG CTGCCAGGAC CATCTTTGAT GGCTTCACCG AGGGTGAGAT TACATTCCAG 
CCTACTTACA AGTACGATAC TGGCTCTGAC GACTGGGACA CCAGTGAGAA GTGTCGTGCA 
CCGGCCTGGT GTGACCGAAT CCTGTGGAAA GGAAAGAACA TCACTCAGCT GAGTTACCAG 
AGCCACATGG CCTTGAAGAC CAGTGACCAC AAGCCTGTCA GCTCAGTGTT TGACATTGGG 
GTGAGGGTTG TCAATGAAGA ACTCTACCGG AAGACCCTGG AGGAAATTGT CCGCTCCCTG 
GATAAAATGG AAAACGCCAA CATTCCTTCT GTGACCCTCT CCAAGCGGGA GTTCTGTTTT 
GAGAATGTGA AGTACATGCA GTTGCAAACC GAGTCCTTCA CGATTCATAA TAGCCAAGTG 
CCCTGTCAGT TTGAATTCAT CAACAAGCCT GACGAAGAGT CCTACTGTAA GCAGTGGCTG 
ACGGCCAGAC CCAGCAAGGG CTTCCTCCTG CCAGATTCGC ATGTTGAGAT TGAACTTGAG 
CTTTTTGTAA ATAAGTCTAC TGCCACAAAA CTCAACTCAG GCAAGGACAC GATTGAAGAC 
ATTCTGGTTT TACACTTGGA GCGGGGAAAG GACTACTTTC TGTCTGTGTC TGGGAACTAC 
CTGCCCAGCT GCTTCGGATC TCCTATCCAT ACATTGTGCT ACATGAGGGA GCCCATCTTG 
GATCTACCAC TGAAAACTGT TAGTGACCTG ACGTTGATGT CAGTGCAGAC TGCAGATGAC 
AGGAGCCAGT TGGAGAACCC CATGGAAATC CCCAAAGAGC TCTGGATGAT GGTGGATTAC 
CTGTACAGAA ATGCCGTCCA GCAGGAAGAT CTGTTTCAGC AGCCAGGTCT GAGGCCAGAG 
TTTGACCATA TAAGGGACTG TCTAGATACT GGGATGATCG ACCAGCTCTG TGCTAACAAC 
CATTCTGTAG CCGAAGCCTT GCTGCTTTTC CTAGAGAGCC TGCCAGAGCC TGTCATCTGT 
TACAGCGCCT ACCATAGCTG CTTGGAGTGT TCTGGCAATT ACGCAGCAAG CAAGCAGATA 
ATTTTAACCC TCCCCAGCTT CCACAAAAAT GTCTTCAACT ACTTGATGGC GTTTTTGCAA 
GAACTGCTGA AAAATTCAGC AAACAATCAT TTGGATGAGA ATATTCTAGC TAGCATATTT 
GGCAGCTTAC TGCTCCGGAA CCCAGCTCGT CACCAAAAGC TTGACATGGC GGAAAAGAAG 
AAGGCCCAAG AGTTTATTCA CCAGTTCCTC TGCGGTCCAC TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Inpp5b ( XM_011240450.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011238752.1 Mus musculus inositol polyphosphate-5-phosphatase B (Inpp5b), transcript variant X3, mRNA.

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CloneID	OMu68018
Clone ID Related Accession (Same CDS sequence)	XM_011240450.2
Accession Version	XM_011240450.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2781bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011240450.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCAGT CTGTGGCAAT CCAGGAGACC CTGGTTGAGG GGGAATACTG CGTCATCCAG 
GCAGTCCAAG GTGTGCTGTG TAAGGGAGAT AGCCGGCAGA GCCGCCTGCT CGGGCTGGTG 
AGGTACCGGC TGGAAAATGA CGCCCAGGAG CATGCTCTCT TCCTGTATAC ACACCGGAGG 
ATGGCCATCA CAGGAGACGA TGTATCTCTG GACCAGATAG TGCCACTCTC AAAAGATTTT 
ATGCTGGAAG AAGTGTCCCC AGATGGTGAA CTCTACATCC TTGGCTCTGA TGTGACAGTA 
CAATTGAACA CAGCTGAACT CAAGCTTGTA TTCCAACTTC CCTTTGGTTC ACACACCAGA 
ACGTTCCTCC AGGAAGTGGC CAGAGCCTGT CCAGGTTTCG ACCCTGAGAC GCGGGATCCC 
GAGTTCGAGT GGCTGTCAAG ACACACATGC GCGGAGCCCG ATGCCGAGTC GCCGAAACCG 
CGCGAGTGGA ATTCGGACCC GGGTACCCGG AGTGGGTTCG CGCCCATTGG AGGAAGCAGG 
CATCAGTCTC GGAATGCACG GCGAGGATTG GAGGATGTCT TGCCTAGGGG CCCTGGCTAC 
ATTCTGCTTT GGGGCGGAGC CGCTGAGGAG CCGGAATTTC TATTGGCGGA GGAGATGCAT 
GAGGGCGGGC CTGTGAGAGG ACGGAGACCG CTCGCCGGGC GGCGGGATGA AGCGCTTGAG 
GAAGCAGACT GGGAAATGTC GGCAGGCGGC GGCTCTCGGG AGCGCGACTG TGCAGGCGTT 
TCTAATGTGG ACAGCTCGAG GCCAAATGGG AGGGGCCCGG ACCAACCCTC CGGAGCCAGG 
TGTCCGGAGA AACCAGAAAA CTCTCTCACA AGACAGAATA AATCTAAGTC TGACATGTCT 
GAAAAGGTTC GCTCCGCCAC AGTCACAGTA TCGGACAAGG CTCACATTTT ATCCGTGCAG 
AAGTTTGGGC TTCGAGACAC AATCGTGAGA TCACACCTCG TGCAGAAGGA AGAGAATTAT 
ACCTACATCC AGAACTTCAG GTTTTTTGTG GGAACCTACA ATGTGAACGG ACAGTCCCCC 
AAAGAATGTC TCCGGCCCTG GCTGAGCCAC AGCGCCCTGG CCCCCGACGT GTACTGTGTA 
GGGTTCCAGG AGCTCGACCT GAGTAAGGAA GCCTTCTTCT TTCACGATAC CCCAAAGGAG 
GAAGAGTGGT TTAAGGCCGT GTCAGAAAGC CTTCACCCAG ACGCCAAGTA CGCAAAGGTG 
AAGTTCGTCC GACTGGTTGG GATTATGTTG CTGCTGTACG TCAAACAGGA ACATGCAGCC 
TATATCTCAG AAGTGGAAGC TGAGACCGTA GGGACAGGAA TCATGGGAAG GATGGGTAAC 
AAAGGAGGAG TGGCGATCAG GTTCCAGCTG CACAACACCA GCATCTGCGT TGTCAATTCC 
CATCTGGCAG CCCACACAGA GGAGTACGAG AGGAGGAACC AAGACTACAG AGACATTTGT 
TCTCGAATGC AGTTCCCTCA GGTGGATCCG AGCCAACCCC CTCTCACCAT TAACAAGCAT 
GATGTGATCT TGTGGCTGGG AGACCTCAAC TACAGGATAG AAGAGCTGGA TGTGGGAAAG 
GTGAAAAAGC TCGTGGAAGA GAAGGCCTTC CAAACCCTGT ATGCGCACGA CCAGCTAAAA 
ATCCAGGTGG CTGCCAGGAC CATCTTTGAT GGCTTCACCG AGGGTGAGAT TACATTCCAG 
CCTACTTACA AGTACGATAC TGGCTCTGAC GACTGGGACA CCAGTGAGAA GTGTCGTGCA 
CCGGCCTGGT GTGACCGAAT CCTGTGGAAA GGAAAGAACA TCACTCAGCT GAGTTACCAG 
AGCCACATGG CCTTGAAGAC CAGTGACCAC AAGCCTGTCA GCTCAGTGTT TGACATTGGG 
GTGAGGGTTG TCAATGAAGA ACTCTACCGG AAGACCCTGG AGGAAATTGT CCGCTCCCTG 
GATAAAATGG AAAACGCCAA CATTCCTTCT GTGACCCTCT CCAAGCGGGA GTTCTGTTTT 
GAGAATGTGA AGTACATGCA GTTGCAAACC GAGTCCTTCA CGATTCATAA TAGCCAAGTG 
CCCTGTCAGT TTGAATTCAT CAACAAGCCT GACGAAGAGT CCTACTGTAA GCAGTGGCTG 
ACGGCCAGAC CCAGCAAGGG CTTCCTCCTG CCAGATTCGC ATGTTGAGAT TGAACTTGAG 
CTTTTTGTAA ATAAGTCTAC TGCCACAAAA CTCAACTCAG GCAAGGACAC GATTGAAGAC 
ATTCTGGTTT TACACTTGGA GCGGGGAAAG GACTACTTTC TGTCTGTGTC TGGGAACTAC 
CTGCCCAGCT GCTTCGGATC TCCTATCCAT ACATTGTGCT ACATGAGGGA GCCCATCTTG 
GATCTACCAC TGAAAACTGT TAGTGACCTG ACGTTGATGT CAGTGCAGAC TGCAGATGAC 
AGGAGCCAGT TGGAGAACCC CATGGAAATC CCCAAAGAGC TCTGGATGAT GGTGGATTAC 
CTGTACAGAA ATGCCGTCCA GCAGGAAGAT CTGTTTCAGC AGCCAGGTCT GAGGCCAGAG 
TTTGACCATA TAAGGGACTG TCTAGATACT GGGATGATCG ACCAGCTCTG TGCTAACAAC 
CATTCTGTAG CCGAAGCCTT GCTGCTTTTC CTAGAGAGCC TGCCAGAGCC TGTCATCTGT 
TACAGCGCCT ACCATAGCTG CTTGGAGTGT TCTGGCAATT ACGCAGCAAG CAAGCAGGTC 
TCTTCCTGTG ACTCAGTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011238752.1
CDS	161..2941
Translation	MDQSVAIQETLVEGEYCVIQAVQGVLCKGDSRQSRLLGLVRYRLENDAQEHALFLYTHRRMAITGDDVSLDQIVPLSKDFMLEEVSPDGELYILGSDVTVQLNTAELKLVFQLPFGSHTRTFLQEVARACPGFDPETRDPEFEWLSRHTCAEPDAESPKPREWNSDPGTRSGFAPIGGSRHQSRNARRGLEDVLPRGPGYILLWGGAAEEPEFLLAEEMHEGGPVRGRRPLAGRRDEALEEADWEMSAGGGSRERDCAGVSNVDSSRPNGRGPDQPSGARCPEKPENSLTRQNKSKSDMSEKVRSATVTVSDKAHILSVQKFGLRDTIVRSHLVQKEENYTYIQNFRFFVGTYNVNGQSPKECLRPWLSHSALAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSESLHPDAKYAKVKFVRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQLHNTSICVVNSHLAAHTEEYERRNQDYRDICSRMQFPQVDPSQPPLTINKHDVILWLGDLNYRIEELDVGKVKKLVEEKAFQTLYAHDQLKIQVAARTIFDGFTEGEITFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGVRVVNEELYRKTLEEIVRSLDKMENANIPSVTLSKREFCFENVKYMQLQTESFTIHNSQVPCQFEFINKPDEESYCKQWLTARPSKGFLLPDSHVEIELELFVNKSTATKLNSGKDTIEDILVLHLERGKDYFLSVSGNYLPSCFGSPIHTLCYMREPILDLPLKTVSDLTLMSVQTADDRSQLENPMEIPKELWMMVDYLYRNAVQQEDLFQQPGLRPEFDHIRDCLDTGMIDQLCANNHSVAEALLLFLESLPEPVICYSAYHSCLECSGNYAASKQVSSCDSV

Target ORF information:

RefSeq Version	XM_011240450.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus inositol polyphosphate-5-phosphatase B (Inpp5b), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011240450.2

ORF Insert Sequence:

ATGGACCAGT CTGTGGCAAT CCAGGAGACC CTGGTTGAGG GGGAATACTG CGTCATCCAG 
GCAGTCCAAG GTGTGCTGTG TAAGGGAGAT AGCCGGCAGA GCCGCCTGCT CGGGCTGGTG 
AGGTACCGGC TGGAAAATGA CGCCCAGGAG CATGCTCTCT TCCTGTATAC ACACCGGAGG 
ATGGCCATCA CAGGAGACGA TGTATCTCTG GACCAGATAG TGCCACTCTC AAAAGATTTT 
ATGCTGGAAG AAGTGTCCCC AGATGGTGAA CTCTACATCC TTGGCTCTGA TGTGACAGTA 
CAATTGAACA CAGCTGAACT CAAGCTTGTA TTCCAACTTC CCTTTGGTTC ACACACCAGA 
ACGTTCCTCC AGGAAGTGGC CAGAGCCTGT CCAGGTTTCG ACCCTGAGAC GCGGGATCCC 
GAGTTCGAGT GGCTGTCAAG ACACACATGC GCGGAGCCCG ATGCCGAGTC GCCGAAACCG 
CGCGAGTGGA ATTCGGACCC GGGTACCCGG AGTGGGTTCG CGCCCATTGG AGGAAGCAGG 
CATCAGTCTC GGAATGCACG GCGAGGATTG GAGGATGTCT TGCCTAGGGG CCCTGGCTAC 
ATTCTGCTTT GGGGCGGAGC CGCTGAGGAG CCGGAATTTC TATTGGCGGA GGAGATGCAT 
GAGGGCGGGC CTGTGAGAGG ACGGAGACCG CTCGCCGGGC GGCGGGATGA AGCGCTTGAG 
GAAGCAGACT GGGAAATGTC GGCAGGCGGC GGCTCTCGGG AGCGCGACTG TGCAGGCGTT 
TCTAATGTGG ACAGCTCGAG GCCAAATGGG AGGGGCCCGG ACCAACCCTC CGGAGCCAGG 
TGTCCGGAGA AACCAGAAAA CTCTCTCACA AGACAGAATA AATCTAAGTC TGACATGTCT 
GAAAAGGTTC GCTCCGCCAC AGTCACAGTA TCGGACAAGG CTCACATTTT ATCCGTGCAG 
AAGTTTGGGC TTCGAGACAC AATCGTGAGA TCACACCTCG TGCAGAAGGA AGAGAATTAT 
ACCTACATCC AGAACTTCAG GTTTTTTGTG GGAACCTACA ATGTGAACGG ACAGTCCCCC 
AAAGAATGTC TCCGGCCCTG GCTGAGCCAC AGCGCCCTGG CCCCCGACGT GTACTGTGTA 
GGGTTCCAGG AGCTCGACCT GAGTAAGGAA GCCTTCTTCT TTCACGATAC CCCAAAGGAG 
GAAGAGTGGT TTAAGGCCGT GTCAGAAAGC CTTCACCCAG ACGCCAAGTA CGCAAAGGTG 
AAGTTCGTCC GACTGGTTGG GATTATGTTG CTGCTGTACG TCAAACAGGA ACATGCAGCC 
TATATCTCAG AAGTGGAAGC TGAGACCGTA GGGACAGGAA TCATGGGAAG GATGGGTAAC 
AAAGGAGGAG TGGCGATCAG GTTCCAGCTG CACAACACCA GCATCTGCGT TGTCAATTCC 
CATCTGGCAG CCCACACAGA GGAGTACGAG AGGAGGAACC AAGACTACAG AGACATTTGT 
TCTCGAATGC AGTTCCCTCA GGTGGATCCG AGCCAACCCC CTCTCACCAT TAACAAGCAT 
GATGTGATCT TGTGGCTGGG AGACCTCAAC TACAGGATAG AAGAGCTGGA TGTGGGAAAG 
GTGAAAAAGC TCGTGGAAGA GAAGGCCTTC CAAACCCTGT ATGCGCACGA CCAGCTAAAA 
ATCCAGGTGG CTGCCAGGAC CATCTTTGAT GGCTTCACCG AGGGTGAGAT TACATTCCAG 
CCTACTTACA AGTACGATAC TGGCTCTGAC GACTGGGACA CCAGTGAGAA GTGTCGTGCA 
CCGGCCTGGT GTGACCGAAT CCTGTGGAAA GGAAAGAACA TCACTCAGCT GAGTTACCAG 
AGCCACATGG CCTTGAAGAC CAGTGACCAC AAGCCTGTCA GCTCAGTGTT TGACATTGGG 
GTGAGGGTTG TCAATGAAGA ACTCTACCGG AAGACCCTGG AGGAAATTGT CCGCTCCCTG 
GATAAAATGG AAAACGCCAA CATTCCTTCT GTGACCCTCT CCAAGCGGGA GTTCTGTTTT 
GAGAATGTGA AGTACATGCA GTTGCAAACC GAGTCCTTCA CGATTCATAA TAGCCAAGTG 
CCCTGTCAGT TTGAATTCAT CAACAAGCCT GACGAAGAGT CCTACTGTAA GCAGTGGCTG 
ACGGCCAGAC CCAGCAAGGG CTTCCTCCTG CCAGATTCGC ATGTTGAGAT TGAACTTGAG 
CTTTTTGTAA ATAAGTCTAC TGCCACAAAA CTCAACTCAG GCAAGGACAC GATTGAAGAC 
ATTCTGGTTT TACACTTGGA GCGGGGAAAG GACTACTTTC TGTCTGTGTC TGGGAACTAC 
CTGCCCAGCT GCTTCGGATC TCCTATCCAT ACATTGTGCT ACATGAGGGA GCCCATCTTG 
GATCTACCAC TGAAAACTGT TAGTGACCTG ACGTTGATGT CAGTGCAGAC TGCAGATGAC 
AGGAGCCAGT TGGAGAACCC CATGGAAATC CCCAAAGAGC TCTGGATGAT GGTGGATTAC 
CTGTACAGAA ATGCCGTCCA GCAGGAAGAT CTGTTTCAGC AGCCAGGTCT GAGGCCAGAG 
TTTGACCATA TAAGGGACTG TCTAGATACT GGGATGATCG ACCAGCTCTG TGCTAACAAC 
CATTCTGTAG CCGAAGCCTT GCTGCTTTTC CTAGAGAGCC TGCCAGAGCC TGTCATCTGT 
TACAGCGCCT ACCATAGCTG CTTGGAGTGT TCTGGCAATT ACGCAGCAAG CAAGCAGGTC 
TCTTCCTGTG ACTCAGTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Kidney Tubular Ablation of
Journal of the American Society of Nephrology : JASN28(5)1399-1407(2017 May)
Inoue K,Balkin DM,Liu L,Nandez R,Wu Y,Tian X,Wang T,Nussbaum R,De Camilli P,Ishibe S

Mouse model for Lowe syndrome/Dent Disease 2 renal tubulopathy.
Journal of the American Society of Nephrology : JASN22(3)443-8(2011 Mar)
Bothwell SP,Chan E,Bernardini IM,Kuo YM,Gahl WA,Nussbaum RL

Species-specific difference in expression and splice-site choice in Inpp5b, an inositol polyphosphate 5-phosphatase paralogous to the enzyme deficient in Lowe Syndrome.
Mammalian genome : official journal of the International Mammalian Genome Society21(9-10)458-66(2010 Oct)
Bothwell SP,Farber LW,Hoagland A,Nussbaum RL

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Inpp5b cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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