The following Herc2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Herc2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu06140 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006540637.3 , XM_006540638.2 , NM_010418.2 , NM_001360080.1 | |
| Accession Version | NM_010418.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 14511bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-11-15 | |
| Organism | Mus musculus(house mouse) | |
| Product | E3 ubiquitin-protein ligase HERC2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY241058.1, AF071173.1, AF061529.1, AK148361.1 and BP754028.1. On Mar 30, 2007 this sequence version replaced NM_010418.1. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF071173.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849384 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGCCTTCTG AGTCTTTCTG TTTGGCTGCC CAGTCTCGCC TTGACTCCAA ATGGTTGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_034548.2 |
| CDS | 170..14680 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_010418.2 |
1 | ATGCCTTCTG AGTCTTTCTG TTTGGCTGCC CAGTCTCGCC TTGACTCCAA ATGGTTGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu06140 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006540637.3 , XM_006540638.2 , NM_010418.2 , NM_001360080.1 | |
| Accession Version | NM_001360080.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 14511bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-24 | |
| Organism | Mus musculus(house mouse) | |
| Product | E3 ubiquitin-protein ligase HERC2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC102121.7 and AC102150.10. On Jan 26, 2018 this sequence version replaced XM_006540638.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF061529.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849385 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGCCTTCTG AGTCTTTCTG TTTGGCTGCC CAGTCTCGCC TTGACTCCAA ATGGTTGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001347009.1 |
| CDS | 120..14630 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001360080.1 |
1 | ATGCCTTCTG AGTCTTTCTG TTTGGCTGCC CAGTCTCGCC TTGACTCCAA ATGGTTGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu06140 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006540637.3 , XM_006540638.2 , NM_010418.2 , NM_001360080.1 | |
| Accession Version | XM_006540637.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 14511bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-07 | |
| Organism | Mus musculus(house mouse) | |
| Product | E3 ubiquitin-protein ligase HERC2 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006540637.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGCCTTCTG AGTCTTTCTG TTTGGCTGCC CAGTCTCGCC TTGACTCCAA ATGGTTGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006540700.1 |
| CDS | 375..14885 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006540637.3 |
1 | ATGCCTTCTG AGTCTTTCTG TTTGGCTGCC CAGTCTCGCC TTGACTCCAA ATGGTTGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu06140 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006540637.3 , XM_006540638.2 , NM_010418.2 , NM_001360080.1 | |
| Accession Version | XM_006540638.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 14511bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-06-21 | |
| Organism | Mus musculus(house mouse) | |
| Product | E3 ubiquitin-protein ligase HERC2 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006540638.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGCCTTCTG AGTCTTTCTG TTTGGCTGCC CAGTCTCGCC TTGACTCCAA ATGGTTGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006540701.1 |
| CDS | 120..14630 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006540638.2 |
1 | ATGCCTTCTG AGTCTTTCTG TTTGGCTGCC CAGTCTCGCC TTGACTCCAA ATGGTTGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu38679 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006540639.2 , XM_006540639.1 | |
| Accession Version | XM_006540639.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 14403bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-07 | |
| Organism | Mus musculus(house mouse) | |
| Product | E3 ubiquitin-protein ligase HERC2 isoform X2 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006540639.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGCCTTCTG AGTCTTTCTG TTTGGCTGCC CAGTCTCGCC TTGACTCCAA ATGGTTGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006540702.1 |
| CDS | 201..14603 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006540639.2 |
1 | ATGCCTTCTG AGTCTTTCTG TTTGGCTGCC CAGTCTCGCC TTGACTCCAA ATGGTTGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu38679 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006540639.2 , XM_006540639.1 | |
| Accession Version | XM_006540639.1 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 14403bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-06-21 | |
| Organism | Mus musculus(house mouse) | |
| Product | E3 ubiquitin-protein ligase HERC2 isoform X2 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGCCTTCTG AGTCTTTCTG TTTGGCTGCC CAGTCTCGCC TTGACTCCAA ATGGTTGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006540702.1 |
| CDS | 166..14568 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006540639.1 |
1 | ATGCCTTCTG AGTCTTTCTG TTTGGCTGCC CAGTCTCGCC TTGACTCCAA ATGGTTGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RNF8/UBC13 ubiquitin signaling suppresses synapse formation in the mammalian brain. |
The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination. |
Novel gene function revealed by mouse mutagenesis screens for models of age-related disease. |
Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling. |
The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway. |
