Gypa cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gypa
Entrez Gene ID	14934
Full Name	glycophorin A
Synonyms	AI853584,CD235a,GPA
General protein information	Preferred Names glycophorin A Names glycophorin-A
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8 C2\|8 38.27 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_010369.3	NP_034499.3	glycophorin-A

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Circulating primitive erythroblasts establish a functional, protein 4.1R-dependent cytoskeletal network prior to enucleating.
Huang YS, Delgadillo LF, Cyr KH, Kingsley PD, An X, McGrath KE, Mohandas N, Conboy JG, Waugh RE, Wan J, Palis J
Scientific reports7(1)5164(2017 Jul)

Targeted erythropoietin selectively stimulates red blood cell expansion in vivo.
Burrill DR, Vernet A, Collins JJ, Silver PA, Way JC
Proceedings of the National Academy of Sciences of the United States of America113(19)5245-50(2016 May)

ADAMTS3 activity is mandatory for embryonic lymphangiogenesis and regulates placental angiogenesis.
Janssen L, Dupont L, Bekhouche M, Noel A, Leduc C, Voz M, Peers B, Cataldo D, Apte SS, Dubail J, Colige A
Angiogenesis19(1)53-65(2016 Jan)

The Poly(C) Binding Protein Pcbp2 and Its Retrotransposed Derivative Pcbp1 Are Independently Essential to Mouse Development.
Ghanem LR, Kromer A, Silverman IM, Chatterji P, Traxler E, Penzo-Mendez A, Weiss MJ, Stanger BZ, Liebhaber SA
Molecular and cellular biology36(2)304-19(2015 Nov)

Kruppel-like factor 1 (KLF1), KLF2, and Myc control a regulatory network essential for embryonic erythropoiesis.
Pang CJ, Lemsaddek W, Alhashem YN, Bondzi C, Redmond LC, Ah-Son N, Dumur CI, Archer KJ, Haar JL, Lloyd JA, Trudel M
Molecular and cellular biology32(13)2628-44(2012 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest that glycophorin A (Gpa) increases expression and activity of Cl-/HCO3- exchanger Ae1, that G719D mutation renders Ae1 mutant constructs GPA-unresponsive, and suggests a role for Ae1 amino acids 22-28 in GPA responsiveness.
Title: Interactions of mouse glycophorin A with the dRTA-related mutant G719D of the mouse Cl-/HCO3- exchanger Ae1.

The resistance of glycophorin A knockout mice against infection with the OB1 variant of Babesia rohaini may be attributed to the effective clearance of the parasitized erythrocytes lacking GPA in the spleen.
Title: Isolation and pathogenic characterization of an OB1 variant of Babesia rodhaini which has a glycophorin A-independent pathway to murine red blood cells.

SCL is a nucleation factor within a higher-order complex required to activate glycophorin A expression
Title: SCL assembles a multifactorial complex that determines glycophorin A expression.

Glycophorin A has an essential role in the expression of O-linked antigens on the erythrocyte membrane.
Title: Glycophorin A requirement for expression of O-linked antigens on the erythrocyte membrane.

The following Gypa gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gypa cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu06061	NM_010369.3 Latest version!	Mus musculus glycophorin A (Gypa), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gypa ( NM_010369.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034499.3 Mus musculus glycophorin A (Gypa), mRNA.

Price & Availability↑

CloneID	OMu06061
Clone ID Related Accession (Same CDS sequence)	NM_010369.3
Accession Version	NM_010369.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 507bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	glycophorin-A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK157851.1, AK162614.1 and BY595233.1. On Aug 5, 2006 this sequence version replaced NM_010369.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK162614.1, AK145998.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849388, SAMN00849390 [ECO:0000348] ##Evidence-Data-END##

ATGACCGAGA GCACAGCTGC TGTGACAACA TCAGGTCATT CTCTTACAAC CACCTTCCAT 
ATACCTTCAA GTCAACATTA CCAAGAAGAG CATTCACCAT CATTGTCAGG ATCAGATTCT 
CTTCTTCAAA TAACCACTCC TGTGGTGGCT TCAACTGTAG GTAACCCAAA TCAGCATTCA 
GCAACAATGT CAACACCAGC TATTCATGTC TCAACTTATC ACACGGCCCC TACTGAAGTG 
TCTGCTGCGT TTGAAGAACA GCCTGTCTCA CCACACATTG GAGGAATGCC GTCACCAATT 
CAACACGATT TTCCTGCACT AGTGATGATA CTCATAATTT TGGGCGTGAT GGCAGGGATT 
ATCGGAACTA TCCTTCTTAT CTCTTACTGT ATCAGCCGAA TGACAAAGAA AAGTTCAGTT 
GACATCCAAT CTCCTGAGGG TGGTGACAAC AGTGTGCCTT TGAGTTCTAT TGAGCAGACT 
CCTAATGAAG AGTCCTCCAA TGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034499.3
CDS	10..516
Translation	MTESTAAVTTSGHSLTTTFHIPSSQHYQEEHSPSLSGSDSLLQITTPVVASTVGNPNQHSATMSTPAIHVSTYHTAPTEVSAAFEEQPVSPHIGGMPSPIQHDFPALVMILIILGVMAGIIGTILLISYCISRMTKKSSVDIQSPEGGDNSVPLSSIEQTPNEESSNV

Target ORF information:

RefSeq Version	NM_010369.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus glycophorin A (Gypa), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010369.3

ORF Insert Sequence:

ATGACCGAGA GCACAGCTGC TGTGACAACA TCAGGTCATT CTCTTACAAC CACCTTCCAT 
ATACCTTCAA GTCAACATTA CCAAGAAGAG CATTCACCAT CATTGTCAGG ATCAGATTCT 
CTTCTTCAAA TAACCACTCC TGTGGTGGCT TCAACTGTAG GTAACCCAAA TCAGCATTCA 
GCAACAATGT CAACACCAGC TATTCATGTC TCAACTTATC ACACGGCCCC TACTGAAGTG 
TCTGCTGCGT TTGAAGAACA GCCTGTCTCA CCACACATTG GAGGAATGCC GTCACCAATT 
CAACACGATT TTCCTGCACT AGTGATGATA CTCATAATTT TGGGCGTGAT GGCAGGGATT 
ATCGGAACTA TCCTTCTTAT CTCTTACTGT ATCAGCCGAA TGACAAAGAA AAGTTCAGTT 
GACATCCAAT CTCCTGAGGG TGGTGACAAC AGTGTGCCTT TGAGTTCTAT TGAGCAGACT 
CCTAATGAAG AGTCCTCCAA TGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Circulating primitive erythroblasts establish a functional, protein 4.1R-dependent cytoskeletal network prior to enucleating.
Scientific reports7(1)5164(2017 Jul)
Huang YS,Delgadillo LF,Cyr KH,Kingsley PD,An X,McGrath KE,Mohandas N,Conboy JG,Waugh RE,Wan J,Palis J

Targeted erythropoietin selectively stimulates red blood cell expansion in vivo.
Proceedings of the National Academy of Sciences of the United States of America113(19)5245-50(2016 May)
Burrill DR,Vernet A,Collins JJ,Silver PA,Way JC

ADAMTS3 activity is mandatory for embryonic lymphangiogenesis and regulates placental angiogenesis.
Angiogenesis19(1)53-65(2016 Jan)
Janssen L,Dupont L,Bekhouche M,Noel A,Leduc C,Voz M,Peers B,Cataldo D,Apte SS,Dubail J,Colige A

The Poly(C) Binding Protein Pcbp2 and Its Retrotransposed Derivative Pcbp1 Are Independently Essential to Mouse Development.
Molecular and cellular biology36(2)304-19(2015 Nov)
Ghanem LR,Kromer A,Silverman IM,Chatterji P,Traxler E,Penzo-Mendez A,Weiss MJ,Stanger BZ,Liebhaber SA

Kruppel-like factor 1 (KLF1), KLF2, and Myc control a regulatory network essential for embryonic erythropoiesis.
Molecular and cellular biology32(13)2628-44(2012 Jul)
Pang CJ,Lemsaddek W,Alhashem YN,Bondzi C,Redmond LC,Ah-Son N,Dumur CI,Archer KJ,Haar JL,Lloyd JA,Trudel M

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Gypa cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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