Eif3a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Eif3a
Entrez Gene ID	13669
Full Name	eukaryotic translation initiation factor 3, subunit A
Synonyms	A830012B05Rik,Csma,Eif3,Eif3s10,mKIAA0139
General protein information	Preferred Names eukaryotic translation initiation factor 3, subunit A Names eukaryotic translation initiation factor 3 subunit A EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 10 (EIF-3 THETA) (EIF3 P167) (EIF3 P180) (EIF3 P185) (P162 PROTEIN) (CENTROSOMIN) centrosomin eIF-3-theta eIF3 p167 eIF3 p180 eIF3 p185 eIF3a eukaryotic translation initiation factor 3, subunit 10 (theta) p162
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 19 Map Location: 19\|19 D3

mRNA and Protein(s)

mRNA	Protein	Name
NM_010123.3	NP_034253.3	eukaryotic translation initiation factor 3 subunit A

Pathways from BioSystems

Homologies

Homo sapiens (human)	EIF3A	NP_003741.1
Pan troglodytes (chimpanzee)	EIF3A	XP_001153575.1
Mus musculus (house mouse)	Eif3a	NP_034253.3
Oryza sativa (rice)	Os01g0120800	NP_001041871.1
Danio rerio (zebrafish)	eif3s10	NP_956114.2
Anopheles gambiae (African malaria mosquito)	EIF3A_ANOGA	XP_312628.5
Caenorhabditis elegans (roundworm)	egl-45	NP_498698.1
Saccharomyces cerevisiae (baker's yeast)	RPG1	NP_009635.1
Arabidopsis thaliana (thale cress)	EIF3A	NP_192881.1
Bos taurus (cattle)	EIF3A	NP_001193243.1
Drosophila melanogaster (fruit fly)	eIF3-S10	NP_649470.2
Kluyveromyces lactis	KLLA0C14498g	XP_452849.1
Neurospora crassa	NCU00040	XP_956151.2
Rattus norvegicus (Norway rat)	Eif3a	NP_001040552.2
Gallus gallus (chicken)	EIF3A	XP_421787.3
Schizosaccharomyces pombe (fission yeast)	tif32	NP_596379.1
Magnaporthe oryzae (rice blast fungus)	MGG_10192	XP_003713822.1
Canis lupus familiaris (dog)	EIF3A	XP_852131.1
Eremothecium gossypii	AGOS_ABL065W	NP_982882.1
Xenopus tropicalis (tropical clawed frog)	eif3a	NP_001096173.1

Gene Ontology
Bibliography

Related articles in PubMed

In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics.
Distler U, Schmeisser MJ, Pelosi A, Reim D, Kuharev J, Weiczner R, Baumgart J, Boeckers TM, Nitsch R, Vogt J, Tenzer S
Proteomics14(21-22)2607-13(2014 Nov)

Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R.
Kraushar ML, Thompson K, Wijeratne HR, Viljetic B, Sakers K, Marson JW, Kontoyiannis DL, Buyske S, Hart RP, Rasin MR
Proceedings of the National Academy of Sciences of the United States of America111(36)E3815-24(2014 Sep)

The m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size control.
Zeng L, Wan Y, Li D, Wu J, Shao M, Chen J, Hui L, Ji H, Zhu X
The Journal of biological chemistry288(42)30087-93(2013 Oct)

The pleiotropic mouse phenotype extra-toes spotting is caused by translation initiation factor Eif3c mutations and is associated with disrupted sonic hedgehog signaling.
Gildea DE, Luetkemeier ES, Bao X, Loftus SK, Mackem S, Yang Y, Pavan WJ, Biesecker LG
FASEB journal : official publication of the Federation of American Societies for Experimental Biology25(5)1596-605(2011 May)

Role of eIF3a in regulating cell cycle progression.
Dong Z, Liu Z, Cui P, Pincheira R, Yang Y, Liu J, Zhang JT
Experimental cell research315(11)1889-94(2009 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The pleiotropic mouse phenotype extra-toes spotting is caused by translation initiation factor Eif3c mutations.
Title: The pleiotropic mouse phenotype extra-toes spotting is caused by translation initiation factor Eif3c mutations and is associated with disrupted sonic hedgehog signaling.

eIF3a expression oscillated with cell cycle and peaked in S phase. Reducing eIF3a expression also reduced cell proliferation rate by elongating cell cycle but did not change the cell cycle distribution.
Title: Role of eIF3a in regulating cell cycle progression.

May play some roles in development and differentiation; decreased eIF3a expression may be a pre-requisite of intestinal epithelial cell differentiation.
Title: Role of eIF3a (eIF3 p170) in intestinal cell differentiation and its association with early development.

Stable expression of a truncated eIF3e in NIH 3T3 cells causes malignant transformation
Title: Malignant transformation by the eukaryotic translation initiation factor 3 subunit p48 (eIF3e).

The following Eif3a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Eif3a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu20961	NM_010123.3 Latest version!	Mus musculus eukaryotic translation initiation factor 3, subunit A (Eif3a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$727.30 $1039.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Eif3a ( NM_010123.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034253.3 Mus musculus eukaryotic translation initiation factor 3, subunit A (Eif3a), mRNA.

Price & Availability↑

CloneID	OMu20961
Clone ID Related Accession (Same CDS sequence)	NM_010123.3
Accession Version	NM_010123.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4035bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	eukaryotic translation initiation factor 3 subunit A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK145132.1, U14172.1, AK013070.1, AK162784.1 and AC163019.5. On May 3, 2007 this sequence version replaced NM_010123.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U14172.1, SRR1660817.248643.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164134, SAMN01164137 [ECO:0000348] ##Evidence-Data-END##

ATGCCGGCCT ATTTCCAGAG GCCGGAAAAT GCCCTCAAGC GCGCCAACGA ATTTCTTGAG 
GTTGGCAAAA AGCAGCCTGC CCTGGATGTT CTTTATGATG TAATGAAAAG TAAGAAGCAC 
AGAACATGGC AGAAGATACA TGAGCCAATT ATGCTGAAAT ACTTGGAACT GTGTGTGGAT 
CTTCGTAAGA GCCACTTGGC TAAGGAAGGG TTATATCAAT ATAAGAACAT ATGCCAACAG 
GTAAACATTA AATCTTTAGA AGATGTTGTT AGGGCATATT TGAAATTAGC AGAGGAAAAA 
ACAGAAGCTG CTAAAGAAGA GTCCCAACAA ATGGTGTTAG ATATAGAAGA TCTGGATAAT 
ATTCAGACTC CTGAGAGTGT TCTCTTAAGT GCAGTAAGTG GGGAAGATAC TCAGGATCGT 
ACTGACAGAT TGCTACTGAC TCCCTGGGTC AAGTTCCTGT GGGAATCATA CAGGCAGTGT 
TTGGACCTTC TTCGAAACAA TTCTAGAGTA GAGCGCCTTT ACCATGATAT CGCCCAACAA 
GCTTTCAAAT TCTGCCTCCA GTATACTCGG AAGGCTGAGT TCCGCAAGCT ATGTGACAAC 
TTGCGAATGC ACTTATCCCA GATTCAGCGC CACCATAACC AAAGCACAGC AATTAATCTT 
AATAATCCAG AGAGCCAGTC TATGCATTTG GAAACCAGAC TTGTTCAGTT GGACAGTGCT 
ATCAGCATGG AATTATGGCA GGAAGCCTTC AAAGCTGTGG AAGATATTCA TGGACTATTT 
TCCTTGTCTA AGAAACCACC TAAGCCTCAG TTGATGGCAA ATTACTATAA CAAAGTTTCA 
ACAGTGTTTT GGAAATCTGG AAATGCTTTG TTCCATGCAT CTACACTTCA TCGTCTTTAT 
CATCTGTCTA GAGAAATGAG AAAGAATCTT ACACAAGAAG AGATGCAAAG AATGTCTACT 
AGAGTCCTTT TGGCGACTCT TTCCATTCCT ATTACTCCTG AGCGAACTGA TATTGCTCGA 
CTTTTGGATA TGGATGGTAT TATAGTTGAG AAGCAGCGAC GCCTTGCCAC ATTGCTAGGT 
CTTCAAGCCC CACCCACACG AATCGGCCTA ATTAATGATA TGGTCAGGTT CAGTGTGCTA 
CAGTATGTTG TCCCAGAAGT GAAAGACCTT TACAACTGGT TGGAGGTGGA ATTCAACCCA 
CTAAAACTCT GTGAGAGAGT TACAAAGGTA TTAAATTGGG TTAGGGAACA ACCTGAAAAA 
GAACCAGAAT TGCAACAATA TGTACCACAA CTCCAGAACA ATACCATACT CCGCCTTCTG 
CAACAGGTGG CACAGATTTA TCAGAGCATT GAGTTTTCTC GTTTGACTTC TCTGGTTCCT 
TTTGTTGATG CTTTCCAACT GGAACGGGCC ATAGTAGATG CAGCCAGGCA CTGTGACCTG 
CAGGTACGTA TTGACCATAC TTCCCGGACT CTGAGTTTTG GATCAGATTT GAATTATGCA 
ACTCGAGAAG ATGCCCCAGT TGGCCCTCAT CTGCAGAGCA TGCCTTCAGA GCAGATAAGA 
AACCAGCTCA CGGCCATGTC CTCAGTGCTT GCCAAAGCAC TTGAAGTCAT CAGACCTGCT 
CACATTCTGC AAGAGAAAGA AGAACAGCAT CAATTGGCAG TTAATGCATA TCTTAAAAAT 
TCAAGAAAAG AGCACCAGAG GATCCTGGCT CGGAGACAGA CAATTGAGGA AAGAAAAGAG 
CGTCTTGAGA GTCTGAATAT TCAACGTGAG AAGGAAGAAC TCGAGCAGAG GGAAGCTGAA 
CTCCAGAAAG TACGAAAGGC TGAAGAAGAA AGGCTGCGCC AAGAGGCAAA GGAGCGAGAG 
AAGGAACGAA TCCTTCAAGA ACACGAGCAA ATCAAGAAGA AAACTGTTCG GGAGCGGTTA 
GAGCAGATCA AGAAGACAGA GCTGGGCGCC AAAGCATTTA AAGATATTGA CATTGAAGAC 
CTTGAAGAAC TGGATCCAGA TTTTATTATG GCCAAACAGG TTGAACAACT GGAGAAAGAA 
AAGAAGGAAC TTCAGGAACG CCTGAAGAAT CAAGAAAAGA AGATTGACTA TTTTGAGAGA 
GCTAAGCGTT TGGAAGAAAT TCCTTTAATA AAGAGTGCTT ATGAGGAACA AAGGGTTAAA 
GACATGGACC TGTGGGAACA GCAAGAAGAA GAAAGAATCA CTACAATGCA GCTAGAACGA 
GAAAAAGCTC TGGAGCATAA GAATAGGATG TCACGAATGT TGGAAGACAG AGATCTATTT 
GTGATGCGCC TCAAAGCTGC CCGGCAGTCT GTCTACGAGG AAAAACTGAA ACAGTTTGAA 
GAGCGCTTAG CAGAAGAAAG GCATAGTCGC CTAGAAGATC GGAAAAGGCA GCGGAAAGAA 
GAACGCAAAA TAACTTATTA CAGAGAAAAG GAAGAAGAAG AGCAGAGGAG GGCAGAGGAG 
CAGATGCTCA AAGAGCGAGA AGAAAGAGAA CGTGCTGAGA GAGCAAAACG GGAGGAAGAA 
CTTAGAGAGT ATCAGGAGCG AGTCAAGAAA CTAGAAGAAG TAGAAAGGAA AAAGCGGCAA 
AGAGAGCTGG AAATTGAAGA AAGGGAAAGG CGCAGAGAGG AAGAAAGGAG ACTTGGTGAT 
GATCCACTTT CTAGGAAGGA CTCTCGGTGG GGAGATAGAG ATTCAGAAGG CACCTGGAGG 
AAAGGACCAG AAGCTGACTC TGAGTGGAGA AGAGGCCCAC CAGAAAAGGA GTGGAGACGA 
GAAACTCGGG ATGATGAGAG GCCTCACAGG AGAGATGAGG ATCGGCTGAG GCGCTTGGGG 
GGTGACGATG AAGAGAGAGA GTCTTCTCTT AGACCGGATG ATGATCGTAT CCCCAGGCGT 
GGCCTGGATG ATGACAGAGG GCCTAGACGT GGTCCCGATG AAGATAGATT TTCTCGTAGA 
GGAACAGATG ATGACCGTCC TTCCTGGCGT AATGCAGATG ATGATAGGCC TCCCAGGCGA 
ATTGGTGATG ATGACAGGGG AAGCTGGCGT CACACAGATG ACGACAGACC ACCCAGACGG 
GGACTGGATG ATGAGAGAGG AAGCTGGCGT ACAGCAGATG AGGACAGAGG ACCTAGACGA 
GGGATGGATG ATGACCGGGG GCCAAGACGA GGAGGTGCTG ATGATGAACG GTCATCCTGG 
CGGAATGCTG ATGATGATAG GGGTCCCAGG AGAGGCATGG ATGATGATAG GGGTCCCAGG 
CGAGGGCTGG ATGATGACCG AGGACCTTGG AGGAATGCTG CTGAAGATAG GATTTCCAGG 
AGAGGTGCAG ATGATGACCG AGGGCCTTGG AGAAATATGG ATGATGATAG GGTTCCTAGA 
AGGGGTGATG ATGCAAGACC TGGTCCTTGG AGACCATTTG TCAAGCCAGG TGGATGGAGA 
GAGAAAGAAA AGGCTAGAGA AGAGAGTTGG GGTCCACCTC GAGAATCAAG ACCATCAGAA 
GAACGTGAAT GGGATAGAGA CAAAGAGAAG GACAGAGATA ATCAAGATCG AGAGGAGAAT 
GACAAAGACC TTGAACGAGA TAGGGACAGA GAGAGAGATG GGGACCGGGA GGATCGATTC 
AGAAGACCCA GGGATGAAGG TGGCTGGAGA AGAGGACCAG CAGAAGAATC TTCAAGCTGG 
AGAGATTCAA GTCGCCGTGA TGATAGGGAC AGGGAAGACC GTCGACGGGA TAGAGATGAT 
CGTCGTGATC TGAGAGACCT GAGAGACAGA AGGGATTTAA GAGATGATAG AGATCGGAGA 
GGACCTCCCC TCAGATCAGA GCGAGAAGAA GCAAGCTCTT GGAGACGCAC TGATGACAGG 
AAAGATGACC GGACTGAAGA GAGGGATCCA CCTCGTCGTG TTCCTCCCCC AGCTCTTTCA 
AGAGATCGAG AAAGAGAGCG AGAACGAGAA GGTGAGAAAG AGAAAGCATC CTGGAGAGCT 
GAGAAAGATA GGGAGTCCCT TCGTCGTACT AAGAATGAAA CTGATGAAGA TGGATGGACC 
ACAGTACGAC GTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034253.3
CDS	177..4211
Translation	MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSKKHRTWQKIHEPIMLKYLELCVDLRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKLAEEKTEAAKEESQQMVLDIEDLDNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDIAQQAFKFCLQYTRKAEFRKLCDNLRMHLSQIQRHHNQSTAINLNNPESQSMHLETRLVQLDSAISMELWQEAFKAVEDIHGLFSLSKKPPKPQLMANYYNKVSTVFWKSGNALFHASTLHRLYHLSREMRKNLTQEEMQRMSTRVLLATLSIPITPERTDIARLLDMDGIIVEKQRRLATLLGLQAPPTRIGLINDMVRFSVLQYVVPEVKDLYNWLEVEFNPLKLCERVTKVLNWVREQPEKEPELQQYVPQLQNNTILRLLQQVAQIYQSIEFSRLTSLVPFVDAFQLERAIVDAARHCDLQVRIDHTSRTLSFGSDLNYATREDAPVGPHLQSMPSEQIRNQLTAMSSVLAKALEVIRPAHILQEKEEQHQLAVNAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRVKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHSRLEDRKRQRKEERKITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDDPLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRETRDDERPHRRDEDRLRRLGGDDEERESSLRPDDDRIPRRGLDDDRGPRRGPDEDRFSRRGTDDDRPSWRNADDDRPPRRIGDDDRGSWRHTDDDRPPRRGLDDERGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGMDDDRGPRRGLDDDRGPWRNAAEDRISRRGADDDRGPWRNMDDDRVPRRGDDARPGPWRPFVKPGGWREKEKAREESWGPPRESRPSEEREWDRDKEKDRDNQDREENDKDLERDRDRERDGDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDREDRRRDRDDRRDLRDLRDRRDLRDDRDRRGPPLRSEREEASSWRRTDDRKDDRTEERDPPRRVPPPALSRDREREREREGEKEKASWRAEKDRESLRRTKNETDEDGWTTVRR

Target ORF information:

RefSeq Version	NM_010123.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus eukaryotic translation initiation factor 3, subunit A (Eif3a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010123.3

ORF Insert Sequence:

ATGCCGGCCT ATTTCCAGAG GCCGGAAAAT GCCCTCAAGC GCGCCAACGA ATTTCTTGAG 
GTTGGCAAAA AGCAGCCTGC CCTGGATGTT CTTTATGATG TAATGAAAAG TAAGAAGCAC 
AGAACATGGC AGAAGATACA TGAGCCAATT ATGCTGAAAT ACTTGGAACT GTGTGTGGAT 
CTTCGTAAGA GCCACTTGGC TAAGGAAGGG TTATATCAAT ATAAGAACAT ATGCCAACAG 
GTAAACATTA AATCTTTAGA AGATGTTGTT AGGGCATATT TGAAATTAGC AGAGGAAAAA 
ACAGAAGCTG CTAAAGAAGA GTCCCAACAA ATGGTGTTAG ATATAGAAGA TCTGGATAAT 
ATTCAGACTC CTGAGAGTGT TCTCTTAAGT GCAGTAAGTG GGGAAGATAC TCAGGATCGT 
ACTGACAGAT TGCTACTGAC TCCCTGGGTC AAGTTCCTGT GGGAATCATA CAGGCAGTGT 
TTGGACCTTC TTCGAAACAA TTCTAGAGTA GAGCGCCTTT ACCATGATAT CGCCCAACAA 
GCTTTCAAAT TCTGCCTCCA GTATACTCGG AAGGCTGAGT TCCGCAAGCT ATGTGACAAC 
TTGCGAATGC ACTTATCCCA GATTCAGCGC CACCATAACC AAAGCACAGC AATTAATCTT 
AATAATCCAG AGAGCCAGTC TATGCATTTG GAAACCAGAC TTGTTCAGTT GGACAGTGCT 
ATCAGCATGG AATTATGGCA GGAAGCCTTC AAAGCTGTGG AAGATATTCA TGGACTATTT 
TCCTTGTCTA AGAAACCACC TAAGCCTCAG TTGATGGCAA ATTACTATAA CAAAGTTTCA 
ACAGTGTTTT GGAAATCTGG AAATGCTTTG TTCCATGCAT CTACACTTCA TCGTCTTTAT 
CATCTGTCTA GAGAAATGAG AAAGAATCTT ACACAAGAAG AGATGCAAAG AATGTCTACT 
AGAGTCCTTT TGGCGACTCT TTCCATTCCT ATTACTCCTG AGCGAACTGA TATTGCTCGA 
CTTTTGGATA TGGATGGTAT TATAGTTGAG AAGCAGCGAC GCCTTGCCAC ATTGCTAGGT 
CTTCAAGCCC CACCCACACG AATCGGCCTA ATTAATGATA TGGTCAGGTT CAGTGTGCTA 
CAGTATGTTG TCCCAGAAGT GAAAGACCTT TACAACTGGT TGGAGGTGGA ATTCAACCCA 
CTAAAACTCT GTGAGAGAGT TACAAAGGTA TTAAATTGGG TTAGGGAACA ACCTGAAAAA 
GAACCAGAAT TGCAACAATA TGTACCACAA CTCCAGAACA ATACCATACT CCGCCTTCTG 
CAACAGGTGG CACAGATTTA TCAGAGCATT GAGTTTTCTC GTTTGACTTC TCTGGTTCCT 
TTTGTTGATG CTTTCCAACT GGAACGGGCC ATAGTAGATG CAGCCAGGCA CTGTGACCTG 
CAGGTACGTA TTGACCATAC TTCCCGGACT CTGAGTTTTG GATCAGATTT GAATTATGCA 
ACTCGAGAAG ATGCCCCAGT TGGCCCTCAT CTGCAGAGCA TGCCTTCAGA GCAGATAAGA 
AACCAGCTCA CGGCCATGTC CTCAGTGCTT GCCAAAGCAC TTGAAGTCAT CAGACCTGCT 
CACATTCTGC AAGAGAAAGA AGAACAGCAT CAATTGGCAG TTAATGCATA TCTTAAAAAT 
TCAAGAAAAG AGCACCAGAG GATCCTGGCT CGGAGACAGA CAATTGAGGA AAGAAAAGAG 
CGTCTTGAGA GTCTGAATAT TCAACGTGAG AAGGAAGAAC TCGAGCAGAG GGAAGCTGAA 
CTCCAGAAAG TACGAAAGGC TGAAGAAGAA AGGCTGCGCC AAGAGGCAAA GGAGCGAGAG 
AAGGAACGAA TCCTTCAAGA ACACGAGCAA ATCAAGAAGA AAACTGTTCG GGAGCGGTTA 
GAGCAGATCA AGAAGACAGA GCTGGGCGCC AAAGCATTTA AAGATATTGA CATTGAAGAC 
CTTGAAGAAC TGGATCCAGA TTTTATTATG GCCAAACAGG TTGAACAACT GGAGAAAGAA 
AAGAAGGAAC TTCAGGAACG CCTGAAGAAT CAAGAAAAGA AGATTGACTA TTTTGAGAGA 
GCTAAGCGTT TGGAAGAAAT TCCTTTAATA AAGAGTGCTT ATGAGGAACA AAGGGTTAAA 
GACATGGACC TGTGGGAACA GCAAGAAGAA GAAAGAATCA CTACAATGCA GCTAGAACGA 
GAAAAAGCTC TGGAGCATAA GAATAGGATG TCACGAATGT TGGAAGACAG AGATCTATTT 
GTGATGCGCC TCAAAGCTGC CCGGCAGTCT GTCTACGAGG AAAAACTGAA ACAGTTTGAA 
GAGCGCTTAG CAGAAGAAAG GCATAGTCGC CTAGAAGATC GGAAAAGGCA GCGGAAAGAA 
GAACGCAAAA TAACTTATTA CAGAGAAAAG GAAGAAGAAG AGCAGAGGAG GGCAGAGGAG 
CAGATGCTCA AAGAGCGAGA AGAAAGAGAA CGTGCTGAGA GAGCAAAACG GGAGGAAGAA 
CTTAGAGAGT ATCAGGAGCG AGTCAAGAAA CTAGAAGAAG TAGAAAGGAA AAAGCGGCAA 
AGAGAGCTGG AAATTGAAGA AAGGGAAAGG CGCAGAGAGG AAGAAAGGAG ACTTGGTGAT 
GATCCACTTT CTAGGAAGGA CTCTCGGTGG GGAGATAGAG ATTCAGAAGG CACCTGGAGG 
AAAGGACCAG AAGCTGACTC TGAGTGGAGA AGAGGCCCAC CAGAAAAGGA GTGGAGACGA 
GAAACTCGGG ATGATGAGAG GCCTCACAGG AGAGATGAGG ATCGGCTGAG GCGCTTGGGG 
GGTGACGATG AAGAGAGAGA GTCTTCTCTT AGACCGGATG ATGATCGTAT CCCCAGGCGT 
GGCCTGGATG ATGACAGAGG GCCTAGACGT GGTCCCGATG AAGATAGATT TTCTCGTAGA 
GGAACAGATG ATGACCGTCC TTCCTGGCGT AATGCAGATG ATGATAGGCC TCCCAGGCGA 
ATTGGTGATG ATGACAGGGG AAGCTGGCGT CACACAGATG ACGACAGACC ACCCAGACGG 
GGACTGGATG ATGAGAGAGG AAGCTGGCGT ACAGCAGATG AGGACAGAGG ACCTAGACGA 
GGGATGGATG ATGACCGGGG GCCAAGACGA GGAGGTGCTG ATGATGAACG GTCATCCTGG 
CGGAATGCTG ATGATGATAG GGGTCCCAGG AGAGGCATGG ATGATGATAG GGGTCCCAGG 
CGAGGGCTGG ATGATGACCG AGGACCTTGG AGGAATGCTG CTGAAGATAG GATTTCCAGG 
AGAGGTGCAG ATGATGACCG AGGGCCTTGG AGAAATATGG ATGATGATAG GGTTCCTAGA 
AGGGGTGATG ATGCAAGACC TGGTCCTTGG AGACCATTTG TCAAGCCAGG TGGATGGAGA 
GAGAAAGAAA AGGCTAGAGA AGAGAGTTGG GGTCCACCTC GAGAATCAAG ACCATCAGAA 
GAACGTGAAT GGGATAGAGA CAAAGAGAAG GACAGAGATA ATCAAGATCG AGAGGAGAAT 
GACAAAGACC TTGAACGAGA TAGGGACAGA GAGAGAGATG GGGACCGGGA GGATCGATTC 
AGAAGACCCA GGGATGAAGG TGGCTGGAGA AGAGGACCAG CAGAAGAATC TTCAAGCTGG 
AGAGATTCAA GTCGCCGTGA TGATAGGGAC AGGGAAGACC GTCGACGGGA TAGAGATGAT 
CGTCGTGATC TGAGAGACCT GAGAGACAGA AGGGATTTAA GAGATGATAG AGATCGGAGA 
GGACCTCCCC TCAGATCAGA GCGAGAAGAA GCAAGCTCTT GGAGACGCAC TGATGACAGG 
AAAGATGACC GGACTGAAGA GAGGGATCCA CCTCGTCGTG TTCCTCCCCC AGCTCTTTCA 
AGAGATCGAG AAAGAGAGCG AGAACGAGAA GGTGAGAAAG AGAAAGCATC CTGGAGAGCT 
GAGAAAGATA GGGAGTCCCT TCGTCGTACT AAGAATGAAA CTGATGAAGA TGGATGGACC 
ACAGTACGAC GTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics.
Proteomics14(21-22)2607-13(2014 Nov)
Distler U,Schmeisser MJ,Pelosi A,Reim D,Kuharev J,Weiczner R,Baumgart J,Boeckers TM,Nitsch R,Vogt J,Tenzer S

Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R.
Proceedings of the National Academy of Sciences of the United States of America111(36)E3815-24(2014 Sep)
Kraushar ML,Thompson K,Wijeratne HR,Viljetic B,Sakers K,Marson JW,Kontoyiannis DL,Buyske S,Hart RP,Rasin MR

The m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size control.
The Journal of biological chemistry288(42)30087-93(2013 Oct)
Zeng L,Wan Y,Li D,Wu J,Shao M,Chen J,Hui L,Ji H,Zhu X

The pleiotropic mouse phenotype extra-toes spotting is caused by translation initiation factor Eif3c mutations and is associated with disrupted sonic hedgehog signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology25(5)1596-605(2011 May)
Gildea DE,Luetkemeier ES,Bao X,Loftus SK,Mackem S,Yang Y,Pavan WJ,Biesecker LG

Role of eIF3a in regulating cell cycle progression.
Experimental cell research315(11)1889-94(2009 Jul)
Dong Z,Liu Z,Cui P,Pincheira R,Yang Y,Liu J,Zhang JT

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Eif3a cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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