Cyp2c39 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cyp2c39
Entrez Gene ID	13098
Full Name	cytochrome P450, family 2, subfamily c, polypeptide 39
Synonyms	CYPIIC39
General protein information	Preferred Names cytochrome P450, family 2, subfamily c, polypeptide 39 Names cytochrome P450 2C39 cytochrome P450, 2c39
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 19 Map Location: 19\|19 C3

mRNA and Protein(s)

mRNA	Protein	Name
XM_030250737.1	XP_030106597.1	cytochrome P450 2C39 isoform X1
NM_001373937.1	NP_001360866.1	cytochrome P450 2C39 isoform 2 precursor
NM_010003.2	NP_034133.2	cytochrome P450 2C39 isoform 1 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Cyp2c38	NP_034132.2
Mus musculus (house mouse)	Cyp2c39	NP_034133.2
Pan troglodytes (chimpanzee)	CYP2C8	XP_001153207.1
Homo sapiens (human)	CYP2C8	NP_000761.3
	CYP2C8	NP_001035300.1
Rattus norvegicus (Norway rat)	Cyp2c7	NP_058854.1
Mus musculus (house mouse)	Cyp2c29	NP_031841.3

Gene Ontology
Bibliography

Related articles in PubMed

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand.
Boj SF, van Es JH, Huch M, Li VS, Jos? A, Hatzis P, Mokry M, Haegebarth A, van den Born M, Chambon P, Voshol P, Dor Y, Cuppen E, Fillat C, Clevers H
Cell151(7)1595-607(2012 Dec)

A comparative analysis of binding sites between mouse CYP2C38 and CYP2C39 based on homology modeling, molecular dynamics simulation and docking studies.
Meng XY, Zheng QC, Zhang HX
Biochimica et biophysica acta1794(7)1066-72(2009 Jul)

Altered vitamin A homeostasis and increased size and adiposity in the rdh1-null mouse.
Zhang M, Hu P, Krois CR, Kane MA, Napoli JL
FASEB journal : official publication of the Federation of American Societies for Experimental Biology21(11)2886-96(2007 Sep)

Emergence of complex rearrangements at translocation breakpoints in a transgenic mouse; implications for mechanisms involved in the formation of chromosome rearrangements.
Kasai F, Yoshihara M, Matsukuma S, O'Brien P, Ferguson-Smith MA
Cytogenetic and genome research119(1-2)83-90(2007)

Mouse liver CYP2C39 is a novel retinoic acid 4-hydroxylase. Its down-regulation offers a molecular basis for liver retinoid accumulation and fibrosis in aryl hydrocarbon receptor-null mice.
Andreola F, Hayhurst GP, Luo G, Ferguson SS, Gonzalez FJ, Goldstein JA, De Luca LM
The Journal of biological chemistry279(5)3434-8(2004 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

By comparison of active site architectures between CYP2C38 and CYP2C39, the possible reasons affecting their substrate binding were proposed
Title: A comparative analysis of binding sites between mouse CYP2C38 and CYP2C39 based on homology modeling, molecular dynamics simulation and docking studies.

CYP2C39 is a novel retinoic acid 4-hydroxylase
Title: Mouse liver CYP2C39 is a novel retinoic acid 4-hydroxylase. Its down-regulation offers a molecular basis for liver retinoid accumulation and fibrosis in aryl hydrocarbon receptor-null mice.

The following Cyp2c39 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cyp2c39 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu05352	NM_010003.2 Latest version!	Mus musculus cytochrome P450, family 2, subfamily c, polypeptide 39 (Cyp2c39), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$286.30 $409.00
OMu87481	NM_001373937.1 Latest version!	Mus musculus cytochrome P450, family 2, subfamily c, polypeptide 39 (Cyp2c39), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu87481	XM_030250737.1 Latest version!	Mus musculus cytochrome P450, family 2, subfamily c, polypeptide 39 (Cyp2c39), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cyp2c39 ( NM_010003.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034133.2 Mus musculus cytochrome P450, family 2, subfamily c, polypeptide 39 (Cyp2c39), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu05352
Clone ID Related Accession (Same CDS sequence)	NM_010003.2
Accession Version	NM_010003.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-04
Organism	Mus musculus(house mouse)
Product	cytochrome P450 2C39 isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC139233.10 and AC117790.23. On Jun 30, 2009 this sequence version replaced NM_010003.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AF047726.1, BC057911.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849386 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACCTTG TCACATTCCT AGTGCTCACT CTCTCTTCTC TCATTCTCCT CTCACTATGG 
AGACAGAGCT GTGGCAGAGG GAGCCTCCCT CCTGGCCCCA CTCCTTTCCC GATTATTGGT 
AATTTCCTTC AGATAGATAT AAAAAACGTC AGCCAATCCT TAACCAATTT CTCAAAAGCC 
TATGGCCCTG TGTTCACTCT GTATTTGGGC TCACGGCCCA CTGTTGTATT ACATGGGTAT 
GAAGCAGTGA AGGAAGCTCT GATTGATCAT GGGGAGGAGT TTTCTGATAG AGGAAGCATT 
CCAATGGTAG AAAAGATTAA TAACGGCCTT GGCATTGTTT TTAGCAATGG AAACAGATGG 
AAAGAGATTA GGCGCTTCAC ACTCACGACC CTGCGAAATT TGGGAATGGG AAAAAGGAAC 
ATTGAGGACC GTGTTCAAGA GGAAGCACAG TGTCTTGTGG AAGAACTAAG GAAAACCAAG 
GGCTCACCTT GTGACCCCAC ATTCATTCTG AGCTGTGCTC CATGCAATGT CATCTGCTCC 
ATTATTTTCC AGGATCGTTT TGATTATAAG GATAAAGATT TTCTTATGCT CATGGAAAAA 
CTAAATGAGA ATGTCAAGAT TCTGAGCTCC CCATGGTTGC AGGTCTGCAA TAATTTCCCC 
TTGCTCATTG ACTATTGTCC AGGAAGTCAT CACAAAGTAC TAAAAAACGT CAAATATATT 
AGAAGTTACC TGTTGGAGAA AATAAAAGAA CACCAAGAAT CACTGGATGT TACAAACCCT 
CGTGATTTTA TTGATTATTA CTTGATTAAA CAAAAACAGG CAAATCACAT CCAACAAGCA 
GAATTTTCAC TTGAAAATCT GGCCTGCACT ATCAATAACC TCTTTGCTGC AGGGACAGAG 
ACAACAAGCA CAACACTGAG ATATGCTCTC CTACTCCTGA TGAAGTACCC AGATGTCACA 
GCTAAAGTCC AGGAAGAGAT TGACCATGTG ATTGGTAGAC ACCGCAGCCC CTGCATGCAG 
GACAGGAACC ACATGCCCTA TACCGATGCC ATGATTCATG AGGTCCAGAG ATTCATCAAC 
CTTGTCCCTA ACAACATACC CCGTGCAGTG ACTTGTGACA TTAAATTTAG GAACTACCTC 
ATCCCCAAGG GAACAACAGT AGTAACGTCA CTGACATCAG TTCTGCATGA CAGCAAGGAG 
TTCCCAAACC CAGAGTTGTT TGACCCTGGC CACTTTCTAG ATGCTAATGG AAACTTTAAG 
AAAAGTGACC ACTTCATGCC TTTCTCAGCA GGAAAACGTG TTTGTGCTGG AGAGGGCCTG 
GCCCGCATGG AGCTGTTTCT ATTCCTGACC ACCATTTTAC AGAACTTTAA ACTGAAATCT 
CTGGTTCACC CAAAAGACAT TGATATGATC CCATTTGTGA ATGGATTAAT AGCTCTGCCA 
CCCCATTACC AGGTCTGCAT CATTCCTCGC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034133.2
CDS	50..1522
Translation	MDLVTFLVLTLSSLILLSLWRQSCGRGSLPPGPTPFPIIGNFLQIDIKNVSQSLTNFSKAYGPVFTLYLGSRPTVVLHGYEAVKEALIDHGEEFSDRGSIPMVEKINNGLGIVFSNGNRWKEIRRFTLTTLRNLGMGKRNIEDRVQEEAQCLVEELRKTKGSPCDPTFILSCAPCNVICSIIFQDRFDYKDKDFLMLMEKLNENVKILSSPWLQVCNNFPLLIDYCPGSHHKVLKNVKYIRSYLLEKIKEHQESLDVTNPRDFIDYYLIKQKQANHIQQAEFSLENLACTINNLFAAGTETTSTTLRYALLLLMKYPDVTAKVQEEIDHVIGRHRSPCMQDRNHMPYTDAMIHEVQRFINLVPNNIPRAVTCDIKFRNYLIPKGTTVVTSLTSVLHDSKEFPNPELFDPGHFLDANGNFKKSDHFMPFSAGKRVCAGEGLARMELFLFLTTILQNFKLKSLVHPKDIDMIPFVNGLIALPPHYQVCIIPR

Target ORF information:

RefSeq Version	NM_010003.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus cytochrome P450, family 2, subfamily c, polypeptide 39 (Cyp2c39), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010003.2

ORF Insert Sequence:

ATGGACCTTG TCACATTCCT AGTGCTCACT CTCTCTTCTC TCATTCTCCT CTCACTATGG 
AGACAGAGCT GTGGCAGAGG GAGCCTCCCT CCTGGCCCCA CTCCTTTCCC GATTATTGGT 
AATTTCCTTC AGATAGATAT AAAAAACGTC AGCCAATCCT TAACCAATTT CTCAAAAGCC 
TATGGCCCTG TGTTCACTCT GTATTTGGGC TCACGGCCCA CTGTTGTATT ACATGGGTAT 
GAAGCAGTGA AGGAAGCTCT GATTGATCAT GGGGAGGAGT TTTCTGATAG AGGAAGCATT 
CCAATGGTAG AAAAGATTAA TAACGGCCTT GGCATTGTTT TTAGCAATGG AAACAGATGG 
AAAGAGATTA GGCGCTTCAC ACTCACGACC CTGCGAAATT TGGGAATGGG AAAAAGGAAC 
ATTGAGGACC GTGTTCAAGA GGAAGCACAG TGTCTTGTGG AAGAACTAAG GAAAACCAAG 
GGCTCACCTT GTGACCCCAC ATTCATTCTG AGCTGTGCTC CATGCAATGT CATCTGCTCC 
ATTATTTTCC AGGATCGTTT TGATTATAAG GATAAAGATT TTCTTATGCT CATGGAAAAA 
CTAAATGAGA ATGTCAAGAT TCTGAGCTCC CCATGGTTGC AGGTCTGCAA TAATTTCCCC 
TTGCTCATTG ACTATTGTCC AGGAAGTCAT CACAAAGTAC TAAAAAACGT CAAATATATT 
AGAAGTTACC TGTTGGAGAA AATAAAAGAA CACCAAGAAT CACTGGATGT TACAAACCCT 
CGTGATTTTA TTGATTATTA CTTGATTAAA CAAAAACAGG CAAATCACAT CCAACAAGCA 
GAATTTTCAC TTGAAAATCT GGCCTGCACT ATCAATAACC TCTTTGCTGC AGGGACAGAG 
ACAACAAGCA CAACACTGAG ATATGCTCTC CTACTCCTGA TGAAGTACCC AGATGTCACA 
GCTAAAGTCC AGGAAGAGAT TGACCATGTG ATTGGTAGAC ACCGCAGCCC CTGCATGCAG 
GACAGGAACC ACATGCCCTA TACCGATGCC ATGATTCATG AGGTCCAGAG ATTCATCAAC 
CTTGTCCCTA ACAACATACC CCGTGCAGTG ACTTGTGACA TTAAATTTAG GAACTACCTC 
ATCCCCAAGG GAACAACAGT AGTAACGTCA CTGACATCAG TTCTGCATGA CAGCAAGGAG 
TTCCCAAACC CAGAGTTGTT TGACCCTGGC CACTTTCTAG ATGCTAATGG AAACTTTAAG 
AAAAGTGACC ACTTCATGCC TTTCTCAGCA GGAAAACGTG TTTGTGCTGG AGAGGGCCTG 
GCCCGCATGG AGCTGTTTCT ATTCCTGACC ACCATTTTAC AGAACTTTAA ACTGAAATCT 
CTGGTTCACC CAAAAGACAT TGATATGATC CCATTTGTGA ATGGATTAAT AGCTCTGCCA 
CCCCATTACC AGGTCTGCAT CATTCCTCGC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cyp2c39 ( NM_001373937.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001360866.1 Mus musculus cytochrome P450, family 2, subfamily c, polypeptide 39 (Cyp2c39), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu87481
Clone ID Related Accession (Same CDS sequence)	XM_030250737.1 , NM_001373937.1
Accession Version	NM_001373937.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-29
Organism	Mus musculus(house mouse)
Product	cytochrome P450 2C39 isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC139233.10 and AC117790.23. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849386 [ECO:0000348] ##Evidence-Data-END##

ATGGATCTGA TCACATTCTT GGTGCTCACT CTCTCCTCTC TCATTCTCCT CTTACTATGG 
AGACAGAGGT CTGGCAGAGG GAGGCTCCCT CCTGGCCCCA CTCCTTTCCC AATTATTGGT 
AATTTCCTTC AGATAGATGG GAAGAACTTC AGCCAATCCT TAACCAATTT CTCAAAAGCC 
TATGGCCCTG TGTTCACTCT GTATTTGGGC TCACGGCCCA CTGTTGTATT ACATGGGTAT 
GAAGCAGTGA AGGAAGCTCT GATTGATCAT GGGGAGGAGT TTTCTGATAG AGGAAGCATT 
CCAATGGTAG AAAAGATTAA TAACGGCCTT GGCATTGTTT TTAGCAATGG AAACAGATGG 
AAAGAGATTA GGCGCTTCAC ACTCACGACC CTGCGAAATT TGGGAATGGG AAAAAGGAAC 
ATTGAGGACC GTGTTCAAGA GGAAGCACAG TGTCTTGTGG AAGAACTAAG GAAAACCAAG 
GGCTCACCTT GTGACCCCAC ATTCATTCTG AGCTGTGCTC CATGCAATGT CATCTGCTCC 
ATTATTTTCC AGGATCGTTT TGATTATAAG GATAAAGATT TTCTTATGCT CATGGAAAAA 
CTAAATGAGA ATGTCAAGAT TCTGAGCTCC CCATGGTTGC AGGTCTGCAA TAATTTCCCC 
TTGCTCATTG ACTATTGTCC AGGAAGTCAT CACAAAGTAC TAAAAAACGT CAAATATATT 
AGAAGTTACC TGTTGGAGAA AATAAAAGAA CACCAAGAAT CACTGGATGT TACAAACCCT 
CGTGATTTTA TTGATTATTA CTTGATTAAA CAAAAACAGG CAAATCACAT CCAACAAGCA 
GAATTTTCAC TTGAAAATCT GGCCTGCACT ATCAATAACC TCTTTGCTGC AGGGACAGAG 
ACAACAAGCA CAACACTGAG ATATGCTCTC CTACTCCTGA TGAAGTACCC AGATGTCACA 
GCTAAAGTCC AGGAAGAGAT TGACCATGTG ATTGGTAGAC ACCGCAGCCC CTGCATGCAG 
GACAGGAACC ACATGCCCTA TACCGATGCC ATGATTCATG AGGTCCAGAG ATTCATCAAC 
CTTGTCCCTA ACAACATACC CCGTGCAGTG ACTTGTGACA TTAAATTTAG GAACTACCTC 
ATCCCCAAGG GAACAACAGT AGTAACGTCA CTGACATCAG TTCTGCATGA CAGCAAGGAG 
TTCCCAAACC CAGAGTTGTT TGACCCTGGC CACTTTCTAG ATGCTAATGG AAACTTTAAG 
AAAAGTGACC ACTTCATGCC TTTCTCAGCA GGAAAACGTG TTTGTGCTGG AGAGGGCCTG 
GCCCGCATGG AGCTGTTTCT ATTCCTGACC ACCATTTTAC AGAACTTTAA ACTGAAATCT 
CTGGTTCACC CAAAAGACAT TGATATGATC CCATTTGTGA ATGGATTAAT AGCTCTGCCA 
CCCCATTACC AGGTCTGCAT CATTCCTCGC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001360866.1
CDS	22..1494
Translation	MDLITFLVLTLSSLILLLLWRQRSGRGRLPPGPTPFPIIGNFLQIDGKNFSQSLTNFSKAYGPVFTLYLGSRPTVVLHGYEAVKEALIDHGEEFSDRGSIPMVEKINNGLGIVFSNGNRWKEIRRFTLTTLRNLGMGKRNIEDRVQEEAQCLVEELRKTKGSPCDPTFILSCAPCNVICSIIFQDRFDYKDKDFLMLMEKLNENVKILSSPWLQVCNNFPLLIDYCPGSHHKVLKNVKYIRSYLLEKIKEHQESLDVTNPRDFIDYYLIKQKQANHIQQAEFSLENLACTINNLFAAGTETTSTTLRYALLLLMKYPDVTAKVQEEIDHVIGRHRSPCMQDRNHMPYTDAMIHEVQRFINLVPNNIPRAVTCDIKFRNYLIPKGTTVVTSLTSVLHDSKEFPNPELFDPGHFLDANGNFKKSDHFMPFSAGKRVCAGEGLARMELFLFLTTILQNFKLKSLVHPKDIDMIPFVNGLIALPPHYQVCIIPR

Target ORF information:

RefSeq Version	NM_001373937.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus cytochrome P450, family 2, subfamily c, polypeptide 39 (Cyp2c39), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001373937.1

ORF Insert Sequence:

ATGGATCTGA TCACATTCTT GGTGCTCACT CTCTCCTCTC TCATTCTCCT CTTACTATGG 
AGACAGAGGT CTGGCAGAGG GAGGCTCCCT CCTGGCCCCA CTCCTTTCCC AATTATTGGT 
AATTTCCTTC AGATAGATGG GAAGAACTTC AGCCAATCCT TAACCAATTT CTCAAAAGCC 
TATGGCCCTG TGTTCACTCT GTATTTGGGC TCACGGCCCA CTGTTGTATT ACATGGGTAT 
GAAGCAGTGA AGGAAGCTCT GATTGATCAT GGGGAGGAGT TTTCTGATAG AGGAAGCATT 
CCAATGGTAG AAAAGATTAA TAACGGCCTT GGCATTGTTT TTAGCAATGG AAACAGATGG 
AAAGAGATTA GGCGCTTCAC ACTCACGACC CTGCGAAATT TGGGAATGGG AAAAAGGAAC 
ATTGAGGACC GTGTTCAAGA GGAAGCACAG TGTCTTGTGG AAGAACTAAG GAAAACCAAG 
GGCTCACCTT GTGACCCCAC ATTCATTCTG AGCTGTGCTC CATGCAATGT CATCTGCTCC 
ATTATTTTCC AGGATCGTTT TGATTATAAG GATAAAGATT TTCTTATGCT CATGGAAAAA 
CTAAATGAGA ATGTCAAGAT TCTGAGCTCC CCATGGTTGC AGGTCTGCAA TAATTTCCCC 
TTGCTCATTG ACTATTGTCC AGGAAGTCAT CACAAAGTAC TAAAAAACGT CAAATATATT 
AGAAGTTACC TGTTGGAGAA AATAAAAGAA CACCAAGAAT CACTGGATGT TACAAACCCT 
CGTGATTTTA TTGATTATTA CTTGATTAAA CAAAAACAGG CAAATCACAT CCAACAAGCA 
GAATTTTCAC TTGAAAATCT GGCCTGCACT ATCAATAACC TCTTTGCTGC AGGGACAGAG 
ACAACAAGCA CAACACTGAG ATATGCTCTC CTACTCCTGA TGAAGTACCC AGATGTCACA 
GCTAAAGTCC AGGAAGAGAT TGACCATGTG ATTGGTAGAC ACCGCAGCCC CTGCATGCAG 
GACAGGAACC ACATGCCCTA TACCGATGCC ATGATTCATG AGGTCCAGAG ATTCATCAAC 
CTTGTCCCTA ACAACATACC CCGTGCAGTG ACTTGTGACA TTAAATTTAG GAACTACCTC 
ATCCCCAAGG GAACAACAGT AGTAACGTCA CTGACATCAG TTCTGCATGA CAGCAAGGAG 
TTCCCAAACC CAGAGTTGTT TGACCCTGGC CACTTTCTAG ATGCTAATGG AAACTTTAAG 
AAAAGTGACC ACTTCATGCC TTTCTCAGCA GGAAAACGTG TTTGTGCTGG AGAGGGCCTG 
GCCCGCATGG AGCTGTTTCT ATTCCTGACC ACCATTTTAC AGAACTTTAA ACTGAAATCT 
CTGGTTCACC CAAAAGACAT TGATATGATC CCATTTGTGA ATGGATTAAT AGCTCTGCCA 
CCCCATTACC AGGTCTGCAT CATTCCTCGC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cyp2c39 ( XM_030250737.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030106597.1 Mus musculus cytochrome P450, family 2, subfamily c, polypeptide 39 (Cyp2c39), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu87481
Clone ID Related Accession (Same CDS sequence)	XM_030250737.1 , NM_001373937.1
Accession Version	XM_030250737.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	cytochrome P450 2C39 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000085.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATCTGA TCACATTCTT GGTGCTCACT CTCTCCTCTC TCATTCTCCT CTTACTATGG 
AGACAGAGGT CTGGCAGAGG GAGGCTCCCT CCTGGCCCCA CTCCTTTCCC AATTATTGGT 
AATTTCCTTC AGATAGATGG GAAGAACTTC AGCCAATCCT TAACCAATTT CTCAAAAGCC 
TATGGCCCTG TGTTCACTCT GTATTTGGGC TCACGGCCCA CTGTTGTATT ACATGGGTAT 
GAAGCAGTGA AGGAAGCTCT GATTGATCAT GGGGAGGAGT TTTCTGATAG AGGAAGCATT 
CCAATGGTAG AAAAGATTAA TAACGGCCTT GGCATTGTTT TTAGCAATGG AAACAGATGG 
AAAGAGATTA GGCGCTTCAC ACTCACGACC CTGCGAAATT TGGGAATGGG AAAAAGGAAC 
ATTGAGGACC GTGTTCAAGA GGAAGCACAG TGTCTTGTGG AAGAACTAAG GAAAACCAAG 
GGCTCACCTT GTGACCCCAC ATTCATTCTG AGCTGTGCTC CATGCAATGT CATCTGCTCC 
ATTATTTTCC AGGATCGTTT TGATTATAAG GATAAAGATT TTCTTATGCT CATGGAAAAA 
CTAAATGAGA ATGTCAAGAT TCTGAGCTCC CCATGGTTGC AGGTCTGCAA TAATTTCCCC 
TTGCTCATTG ACTATTGTCC AGGAAGTCAT CACAAAGTAC TAAAAAACGT CAAATATATT 
AGAAGTTACC TGTTGGAGAA AATAAAAGAA CACCAAGAAT CACTGGATGT TACAAACCCT 
CGTGATTTTA TTGATTATTA CTTGATTAAA CAAAAACAGG CAAATCACAT CCAACAAGCA 
GAATTTTCAC TTGAAAATCT GGCCTGCACT ATCAATAACC TCTTTGCTGC AGGGACAGAG 
ACAACAAGCA CAACACTGAG ATATGCTCTC CTACTCCTGA TGAAGTACCC AGATGTCACA 
GCTAAAGTCC AGGAAGAGAT TGACCATGTG ATTGGTAGAC ACCGCAGCCC CTGCATGCAG 
GACAGGAACC ACATGCCCTA TACCGATGCC ATGATTCATG AGGTCCAGAG ATTCATCAAC 
CTTGTCCCTA ACAACATACC CCGTGCAGTG ACTTGTGACA TTAAATTTAG GAACTACCTC 
ATCCCCAAGG GAACAACAGT AGTAACGTCA CTGACATCAG TTCTGCATGA CAGCAAGGAG 
TTCCCAAACC CAGAGTTGTT TGACCCTGGC CACTTTCTAG ATGCTAATGG AAACTTTAAG 
AAAAGTGACC ACTTCATGCC TTTCTCAGCA GGAAAACGTG TTTGTGCTGG AGAGGGCCTG 
GCCCGCATGG AGCTGTTTCT ATTCCTGACC ACCATTTTAC AGAACTTTAA ACTGAAATCT 
CTGGTTCACC CAAAAGACAT TGATATGATC CCATTTGTGA ATGGATTAAT AGCTCTGCCA 
CCCCATTACC AGGTCTGCAT CATTCCTCGC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030106597.1
CDS	32..1504
Translation	MDLITFLVLTLSSLILLLLWRQRSGRGRLPPGPTPFPIIGNFLQIDGKNFSQSLTNFSKAYGPVFTLYLGSRPTVVLHGYEAVKEALIDHGEEFSDRGSIPMVEKINNGLGIVFSNGNRWKEIRRFTLTTLRNLGMGKRNIEDRVQEEAQCLVEELRKTKGSPCDPTFILSCAPCNVICSIIFQDRFDYKDKDFLMLMEKLNENVKILSSPWLQVCNNFPLLIDYCPGSHHKVLKNVKYIRSYLLEKIKEHQESLDVTNPRDFIDYYLIKQKQANHIQQAEFSLENLACTINNLFAAGTETTSTTLRYALLLLMKYPDVTAKVQEEIDHVIGRHRSPCMQDRNHMPYTDAMIHEVQRFINLVPNNIPRAVTCDIKFRNYLIPKGTTVVTSLTSVLHDSKEFPNPELFDPGHFLDANGNFKKSDHFMPFSAGKRVCAGEGLARMELFLFLTTILQNFKLKSLVHPKDIDMIPFVNGLIALPPHYQVCIIPR

Target ORF information:

RefSeq Version	XM_030250737.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus cytochrome P450, family 2, subfamily c, polypeptide 39 (Cyp2c39), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030250737.1

ORF Insert Sequence:

ATGGATCTGA TCACATTCTT GGTGCTCACT CTCTCCTCTC TCATTCTCCT CTTACTATGG 
AGACAGAGGT CTGGCAGAGG GAGGCTCCCT CCTGGCCCCA CTCCTTTCCC AATTATTGGT 
AATTTCCTTC AGATAGATGG GAAGAACTTC AGCCAATCCT TAACCAATTT CTCAAAAGCC 
TATGGCCCTG TGTTCACTCT GTATTTGGGC TCACGGCCCA CTGTTGTATT ACATGGGTAT 
GAAGCAGTGA AGGAAGCTCT GATTGATCAT GGGGAGGAGT TTTCTGATAG AGGAAGCATT 
CCAATGGTAG AAAAGATTAA TAACGGCCTT GGCATTGTTT TTAGCAATGG AAACAGATGG 
AAAGAGATTA GGCGCTTCAC ACTCACGACC CTGCGAAATT TGGGAATGGG AAAAAGGAAC 
ATTGAGGACC GTGTTCAAGA GGAAGCACAG TGTCTTGTGG AAGAACTAAG GAAAACCAAG 
GGCTCACCTT GTGACCCCAC ATTCATTCTG AGCTGTGCTC CATGCAATGT CATCTGCTCC 
ATTATTTTCC AGGATCGTTT TGATTATAAG GATAAAGATT TTCTTATGCT CATGGAAAAA 
CTAAATGAGA ATGTCAAGAT TCTGAGCTCC CCATGGTTGC AGGTCTGCAA TAATTTCCCC 
TTGCTCATTG ACTATTGTCC AGGAAGTCAT CACAAAGTAC TAAAAAACGT CAAATATATT 
AGAAGTTACC TGTTGGAGAA AATAAAAGAA CACCAAGAAT CACTGGATGT TACAAACCCT 
CGTGATTTTA TTGATTATTA CTTGATTAAA CAAAAACAGG CAAATCACAT CCAACAAGCA 
GAATTTTCAC TTGAAAATCT GGCCTGCACT ATCAATAACC TCTTTGCTGC AGGGACAGAG 
ACAACAAGCA CAACACTGAG ATATGCTCTC CTACTCCTGA TGAAGTACCC AGATGTCACA 
GCTAAAGTCC AGGAAGAGAT TGACCATGTG ATTGGTAGAC ACCGCAGCCC CTGCATGCAG 
GACAGGAACC ACATGCCCTA TACCGATGCC ATGATTCATG AGGTCCAGAG ATTCATCAAC 
CTTGTCCCTA ACAACATACC CCGTGCAGTG ACTTGTGACA TTAAATTTAG GAACTACCTC 
ATCCCCAAGG GAACAACAGT AGTAACGTCA CTGACATCAG TTCTGCATGA CAGCAAGGAG 
TTCCCAAACC CAGAGTTGTT TGACCCTGGC CACTTTCTAG ATGCTAATGG AAACTTTAAG 
AAAAGTGACC ACTTCATGCC TTTCTCAGCA GGAAAACGTG TTTGTGCTGG AGAGGGCCTG 
GCCCGCATGG AGCTGTTTCT ATTCCTGACC ACCATTTTAC AGAACTTTAA ACTGAAATCT 
CTGGTTCACC CAAAAGACAT TGATATGATC CCATTTGTGA ATGGATTAAT AGCTCTGCCA 
CCCCATTACC AGGTCTGCAT CATTCCTCGC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand.
Cell151(7)1595-607(2012 Dec)
Boj SF,van Es JH,Huch M,Li VS,Jos? A,Hatzis P,Mokry M,Haegebarth A,van den Born M,Chambon P,Voshol P,Dor Y,Cuppen E,Fillat C,Clevers H

A comparative analysis of binding sites between mouse CYP2C38 and CYP2C39 based on homology modeling, molecular dynamics simulation and docking studies.
Biochimica et biophysica acta1794(7)1066-72(2009 Jul)
Meng XY,Zheng QC,Zhang HX

Altered vitamin A homeostasis and increased size and adiposity in the rdh1-null mouse.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology21(11)2886-96(2007 Sep)
Zhang M,Hu P,Krois CR,Kane MA,Napoli JL

Emergence of complex rearrangements at translocation breakpoints in a transgenic mouse; implications for mechanisms involved in the formation of chromosome rearrangements.
Cytogenetic and genome research119(1-2)83-90(2007)
Kasai F,Yoshihara M,Matsukuma S,O'Brien P,Ferguson-Smith MA

Mouse liver CYP2C39 is a novel retinoic acid 4-hydroxylase. Its down-regulation offers a molecular basis for liver retinoid accumulation and fibrosis in aryl hydrocarbon receptor-null mice.
The Journal of biological chemistry279(5)3434-8(2004 Jan)
Andreola F,Hayhurst GP,Luo G,Ferguson SS,Gonzalez FJ,Goldstein JA,De Luca LM

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Cyp2c39 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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