Csn1s2b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Csn1s2b
Entrez Gene ID	12992
Full Name	casein alpha s2-like B
Synonyms	AW987150,Csnd,Csne
General protein information	Preferred Names casein alpha s2-like B Names alpha-S2-casein-like B casein delta epsilon-casein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5 E1\|5 43.56 cM
Summary	This gene is a member of the alpha-s2-like casein gene family, and this gene product is a calcium-sensitive casein. Members of this gene family are organized as a gene cluster that is conserved in its order, but with greater conservation amongst orthologs than paralogs. The protein encoded by this gene interacts with other casein proteins to form a micelle structure, and is a major source of protein in milk. This structure is important for the transport of calcium, phosphate, and protein. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Aug 2014].

mRNA and Protein(s)

mRNA	Protein	Name
NM_009973.3	NP_034103.2	alpha-S2-casein-like B isoform 1 precursor
NM_001301334.1	NP_001288263.1	alpha-S2-casein-like B isoform 2 precursor
NM_001301335.1	NP_001288264.1	alpha-S2-casein-like B isoform 3 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Csn1s2b	NP_775129.1
Mus musculus (house mouse)	Csn1s2b	NP_034103.2

Gene Ontology
Bibliography

Related articles in PubMed

Multispecies comparative analysis of a mammalian-specific genomic domain encoding secretory proteins.
Rijnkels M, Elnitski L, Miller W, Rosen JM
Genomics82(4)417-32(2003 Oct)

Physical mapping of the murine casein locus reveals the gene order as alpha-beta-gamma-epsilon-kappa.
George S, Clark AJ, Archibald AL
DNA and cell biology16(4)477-84(1997 Apr)

Structure and expression of the mouse casein gene locus.
Rijnkels M, Wheeler DA, de Boer HA, Pieper FR
Mammalian genome : official journal of the International Mammalian Genome Society8(1)9-15(1997 Jan)

Restriction map of two yeast artificial chromosomes spanning the murine casein locus.
Tomlinson AM, Cox RD, Lehrach HR, Dalrymple MA
Mammalian genome : official journal of the International Mammalian Genome Society7(7)542-4(1996 Jul)

Nucleotide sequence of cloned cDNA coding for mouse epsilon casein.
Hennighausen LG, Steudle A, Sippel AE
European journal of biochemistry126(3)569-72(1982 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Csn1s2b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Csn1s2b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu67467	NM_001301334.1 Latest version!	Mus musculus casein alpha s2-like B (Csn1s2b), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu67468	NM_001301335.1 Latest version!	Mus musculus casein alpha s2-like B (Csn1s2b), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu05245	NM_009973.3 Latest version!	Mus musculus casein alpha s2-like B (Csn1s2b), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Csn1s2b ( NM_001301334.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001288263.1 Mus musculus casein alpha s2-like B (Csn1s2b), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu67467
Clone ID Related Accession (Same CDS sequence)	NM_001301334.1
Accession Version	NM_001301334.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 417bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	alpha-S2-casein-like B isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK164767.1, AK164763.1 and AK085744.1. On Aug 7, 2014 this sequence version replaced XM_006534763.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site, compared to variant 1. It encodes isoform 2 which is shorter than isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK164763.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN01164137 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGTTCA TCATTCTTAC TTGCCTTTTG GCCGTTGCTC TTGCAAAGCA GAGGATGGAG 
CAATACATCT CCAGTGAGGA GTCCATGGAT AACTCTCAAG AAAACTTTAA GCAGAATATG 
GATGTGGCCT TTTTTCCCAG TCAGGAAACT GTAGAGAACA TTTACATTCC CCAAATGGAA 
TCTGTTGAAG CTCCCATGAA GGTATCTGAC ATCATTTCTC AGCAACAATA CAACCAGAAA 
ATGATGGACA TGAGTAAAAC TGTGATGACT GAAGAAAGTA AGAACATCCA AGACTACATG 
AACAAAATGA AACGATACAG CAAGATCACC TGGCCACAGT TTGTAAAGCT TCTCCATCAA 
TACCAGAAAA CCATGACCCC GTGGAGCTAT TACCCATCTA CCCCCAGCCA GGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001288263.1
CDS	58..474
Translation	MKFIILTCLLAVALAKQRMEQYISSEESMDNSQENFKQNMDVAFFPSQETVENIYIPQMESVEAPMKVSDIISQQQYNQKMMDMSKTVMTEESKNIQDYMNKMKRYSKITWPQFVKLLHQYQKTMTPWSYYPSTPSQV

Target ORF information:

RefSeq Version	NM_001301334.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus casein alpha s2-like B (Csn1s2b), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001301334.1

ORF Insert Sequence:

ATGAAGTTCA TCATTCTTAC TTGCCTTTTG GCCGTTGCTC TTGCAAAGCA GAGGATGGAG 
CAATACATCT CCAGTGAGGA GTCCATGGAT AACTCTCAAG AAAACTTTAA GCAGAATATG 
GATGTGGCCT TTTTTCCCAG TCAGGAAACT GTAGAGAACA TTTACATTCC CCAAATGGAA 
TCTGTTGAAG CTCCCATGAA GGTATCTGAC ATCATTTCTC AGCAACAATA CAACCAGAAA 
ATGATGGACA TGAGTAAAAC TGTGATGACT GAAGAAAGTA AGAACATCCA AGACTACATG 
AACAAAATGA AACGATACAG CAAGATCACC TGGCCACAGT TTGTAAAGCT TCTCCATCAA 
TACCAGAAAA CCATGACCCC GTGGAGCTAT TACCCATCTA CCCCCAGCCA GGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Csn1s2b ( NM_001301335.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001288264.1 Mus musculus casein alpha s2-like B (Csn1s2b), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu67468
Clone ID Related Accession (Same CDS sequence)	NM_001301335.1
Accession Version	NM_001301335.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 399bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	alpha-S2-casein-like B isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK164767.1 and AK085744.1. Transcript Variant: This variant (3) lacks an in-frame exon, compared to variant 1. It encodes isoform 3 which is shorter than isoform 1. ##Evidence-Data-START## Transcript exon combination :: BB661711.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN01164137 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGTTCA TCATTCTTAC TTGCCTTTTG GCCGTTGCTC TTGCAAAGCA GAGGATGGAG 
CAATACATCT CCAGTGAGGA GTCCATGGAT AACTCTCAAG AAAACTTTAA GCAGAATATG 
GATGTGGCCT TTTTTCCCAG TCAGGAATCT GTTGAAGCTC CCATGAAGGT ATCTGACATC 
ATTTCTCAGC AACAATACAA CCAGAAAATG ATGGACATGA GTGTGAGTGC CAGAGAGAAA 
ACTGTGATGA CTGAAGAAAG TAAGAACATC CAAGACTACA TGAACAAAAT GAAACGATAC 
AGCAAGATCA CCTGGCCACA GTTTGTAAAG CTTCTCCATC AATACCAGAA AACCATGACC 
CCGTGGAGCT ATTACCCATC TACCCCCAGC CAGGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001288264.1
CDS	58..456
Translation	MKFIILTCLLAVALAKQRMEQYISSEESMDNSQENFKQNMDVAFFPSQESVEAPMKVSDIISQQQYNQKMMDMSVSAREKTVMTEESKNIQDYMNKMKRYSKITWPQFVKLLHQYQKTMTPWSYYPSTPSQV

Target ORF information:

RefSeq Version	NM_001301335.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus casein alpha s2-like B (Csn1s2b), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001301335.1

ORF Insert Sequence:

ATGAAGTTCA TCATTCTTAC TTGCCTTTTG GCCGTTGCTC TTGCAAAGCA GAGGATGGAG 
CAATACATCT CCAGTGAGGA GTCCATGGAT AACTCTCAAG AAAACTTTAA GCAGAATATG 
GATGTGGCCT TTTTTCCCAG TCAGGAATCT GTTGAAGCTC CCATGAAGGT ATCTGACATC 
ATTTCTCAGC AACAATACAA CCAGAAAATG ATGGACATGA GTGTGAGTGC CAGAGAGAAA 
ACTGTGATGA CTGAAGAAAG TAAGAACATC CAAGACTACA TGAACAAAAT GAAACGATAC 
AGCAAGATCA CCTGGCCACA GTTTGTAAAG CTTCTCCATC AATACCAGAA AACCATGACC 
CCGTGGAGCT ATTACCCATC TACCCCCAGC CAGGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Csn1s2b ( NM_009973.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034103.2 Mus musculus casein alpha s2-like B (Csn1s2b), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu05245
Clone ID Related Accession (Same CDS sequence)	NM_009973.3
Accession Version	NM_009973.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 432bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	alpha-S2-casein-like B isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK164767.1 and AK085744.1. On Aug 7, 2014 this sequence version replaced NM_009973.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: AK085744.1, AK164768.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849384, SAMN01164133 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGTTCA TCATTCTTAC TTGCCTTTTG GCCGTTGCTC TTGCAAAGCA GAGGATGGAG 
CAATACATCT CCAGTGAGGA GTCCATGGAT AACTCTCAAG AAAACTTTAA GCAGAATATG 
GATGTGGCCT TTTTTCCCAG TCAGGAAACT GTAGAGAACA TTTACATTCC CCAAATGGAA 
TCTGTTGAAG CTCCCATGAA GGTATCTGAC ATCATTTCTC AGCAACAATA CAACCAGAAA 
ATGATGGACA TGAGTGTGAG TGCCAGAGAG AAAACTGTGA TGACTGAAGA AAGTAAGAAC 
ATCCAAGACT ACATGAACAA AATGAAACGA TACAGCAAGA TCACCTGGCC ACAGTTTGTA 
AAGCTTCTCC ATCAATACCA GAAAACCATG ACCCCGTGGA GCTATTACCC ATCTACCCCC 
AGCCAGGTTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034103.2
CDS	58..489
Translation	MKFIILTCLLAVALAKQRMEQYISSEESMDNSQENFKQNMDVAFFPSQETVENIYIPQMESVEAPMKVSDIISQQQYNQKMMDMSVSAREKTVMTEESKNIQDYMNKMKRYSKITWPQFVKLLHQYQKTMTPWSYYPSTPSQV

Target ORF information:

RefSeq Version	NM_009973.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus casein alpha s2-like B (Csn1s2b), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009973.3

ORF Insert Sequence:

ATGAAGTTCA TCATTCTTAC TTGCCTTTTG GCCGTTGCTC TTGCAAAGCA GAGGATGGAG 
CAATACATCT CCAGTGAGGA GTCCATGGAT AACTCTCAAG AAAACTTTAA GCAGAATATG 
GATGTGGCCT TTTTTCCCAG TCAGGAAACT GTAGAGAACA TTTACATTCC CCAAATGGAA 
TCTGTTGAAG CTCCCATGAA GGTATCTGAC ATCATTTCTC AGCAACAATA CAACCAGAAA 
ATGATGGACA TGAGTGTGAG TGCCAGAGAG AAAACTGTGA TGACTGAAGA AAGTAAGAAC 
ATCCAAGACT ACATGAACAA AATGAAACGA TACAGCAAGA TCACCTGGCC ACAGTTTGTA 
AAGCTTCTCC ATCAATACCA GAAAACCATG ACCCCGTGGA GCTATTACCC ATCTACCCCC 
AGCCAGGTTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Multispecies comparative analysis of a mammalian-specific genomic domain encoding secretory proteins.
Genomics82(4)417-32(2003 Oct)
Rijnkels M,Elnitski L,Miller W,Rosen JM

Physical mapping of the murine casein locus reveals the gene order as alpha-beta-gamma-epsilon-kappa.
DNA and cell biology16(4)477-84(1997 Apr)
George S,Clark AJ,Archibald AL

Structure and expression of the mouse casein gene locus.
Mammalian genome : official journal of the International Mammalian Genome Society8(1)9-15(1997 Jan)
Rijnkels M,Wheeler DA,de Boer HA,Pieper FR

Restriction map of two yeast artificial chromosomes spanning the murine casein locus.
Mammalian genome : official journal of the International Mammalian Genome Society7(7)542-4(1996 Jul)
Tomlinson AM,Cox RD,Lehrach HR,Dalrymple MA

Nucleotide sequence of cloned cDNA coding for mouse epsilon casein.
European journal of biochemistry126(3)569-72(1982 Sep)
Hennighausen LG,Steudle A,Sippel AE

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Csn1s2b cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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