Crmp1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Crmp1
Entrez Gene ID	12933
Full Name	collapsin response mediator protein 1
Synonyms	CRMP-1,DRP-1,Dpysl1,ULIP-3,Ulip3
General protein information	Preferred Names collapsin response mediator protein 1 Names dihydropyrimidinase-related protein 1 unc-33-like phosphoprotein 3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5 B3\|5 19.96 cM
Summary	This gene encodes a protein that is part of the collapsin response mediator protein family. The family is comprised of five, homologous cytosolic phosphoproteins that are expressed in developing and adult nervous tissue and mediate signaling to transduce responses to extracellular cues. This protein is a Semaphorin 3A signaling molecule that regulates collapse of the growth cone. The growth cone mediates axonal pathfinding in neurons. This protein is reported to represent a new class of microtubule-associated proteins. In humans this protein is reported to inhibit cancer cell invasion. In mouse deficiency of this gene may be associated with impaired spatial memory performance. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jan 2013].

mRNA and Protein(s)

mRNA	Protein	Name
NM_007765.4	NP_031791.3	dihydropyrimidinase-related protein 1 isoform 2
NM_001136058.2	NP_001129530.1	dihydropyrimidinase-related protein 1 isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	CRMP1	NP_001014809.1
	CRMP1	XP_001093945.1
Mus musculus (house mouse)	Crmp1	NP_001129530.1
Canis lupus familiaris (dog)	CRMP1	XP_536244.3
Bos taurus (cattle)	CRMP1	NP_001178950.1
Rattus norvegicus (Norway rat)	Crmp1	NP_037064.1
Pan troglodytes (chimpanzee)	CRMP1	XP_003310286.1
Danio rerio (zebrafish)	crmp1	NP_001018561.1
Gallus gallus (chicken)	CRMP1	NP_989826.1
Xenopus tropicalis (tropical clawed frog)	crmp1	NP_001072314.1

Gene Ontology
Bibliography

Related articles in PubMed

A functional coupling between CRMP1 and Na
Yamane M, Yamashita N, Hida T, Kamiya Y, Nakamura F, Kolattukudy P, Goshima Y
Journal of cell science130(8)1393-1403(2017 04)

CRMP1 and CRMP4 are required for proper orientation of dendrites of cerebral pyramidal neurons in the developing mouse brain.
Takaya R, Nagai J, Piao W, Niisato E, Nakabayashi T, Yamazaki Y, Nakamura F, Yamashita N, Kolattukudy P, Goshima Y, Ohshima T
Brain research1655161-167(2017 01)

CRMP1 and CRMP2 have synergistic but distinct roles in dendritic development.
Makihara H, Nakai S, Ohkubo W, Yamashita N, Nakamura F, Kiyonari H, Shioi G, Jitsuki-Takahashi A, Nakamura H, Tanaka F, Akase T, Kolattukudy P, Goshima Y
Genes to cells : devoted to molecular & cellular mechanisms21(9)994-1005(2016 Sep)

Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun.
Gurdziel K, Vogt KR, Walton KD, Schneider GK, Gumucio DL
Developmental dynamics : an official publication of the American Association of Anatomists245(5)614-26(2016 May)

Mice deficient in collapsin response mediator protein-1 exhibit impaired long-term potentiation and impaired spatial learning and memory.
Su KY, Chien WL, Fu WM, Yu IS, Huang HP, Huang PH, Lin SR, Shih JY, Lin YL, Hsueh YP, Yang PC, Lin SW
The Journal of neuroscience : the official journal of the Society for Neuroscience27(10)2513-24(2007 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

this paper shows that Nav1.7, by coupling with CRMP1, mediates the axonal retrograde signaling of Sema3A in axonal guidance
Title: A functional coupling between CRMP1 and Na

Results indicate that CRMP1 and CRMP4 regulate proper orientation of the basal dendrites of layer V neurons in the cerebral cortex during development.
Title: CRMP1 and CRMP4 are required for proper orientation of dendrites of cerebral pyramidal neurons in the developing mouse brain.

We generated CRMP2 gene-deficient (crmp2(-/-) ) mice. The crmp2(-/-) mice showed irregular development of dendritic spines in cortical neurons. The level of CRMP1 was increased in crmp2(-/-) , but the level of CRMP2 was not altered in crmp1(-/-).The phenotypic defects had no genetic interaction between crmp1 and crmp2.
Title: CRMP1 and CRMP2 have synergistic but distinct roles in dendritic development.

LCRMP-1 and CRMP-1 have opposing functions in regulating cancer cell invasion and metastasis
Title: The ability of LCRMP-1 to promote cancer invasion by enhancing filopodia formation is antagonized by CRMP-1.

Data demonstrate that CRMP1 tyrosine 504 is a primary target of the Src family of tyrosine kinases (SFKs), specifically Fyn.
Title: Fyn promotes phosphorylation of collapsin response mediator protein 1 at tyrosine 504, a novel, isoform-specific regulatory site.

The following Crmp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Crmp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu00761	NM_007765.4 Latest version!	Mus musculus collapsin response mediator protein 1 (Crmp1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$335.30 $479.00
OMu06297	NM_001136058.2 Latest version!	Mus musculus collapsin response mediator protein 1 (Crmp1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Crmp1 ( NM_007765.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031791.3 Mus musculus collapsin response mediator protein 1 (Crmp1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu00761
Clone ID Related Accession (Same CDS sequence)	NM_007765.4
Accession Version	NM_007765.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1719bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Mus musculus(house mouse)
Product	dihydropyrimidinase-related protein 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CX562443.1, BC031738.1 and BM116580.2. On Jan 18, 2013 this sequence version replaced NM_007765.3. Transcript Variant: This variant (2) contains an alternate 5'-most exon and initiates translation at an alternate start codon compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB006714.1, BC031738.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCTCATC AGGGGAAGAA GAGCATCCCG CACATCACCA GTGACCGGCT CCTCATCAGA 
GGTGGACGCA TCATCAATGA TGACCAGTCC TTCTACGCCG ATGTCTACCT AGAAGATGGA 
CTCATAAAAC AAATAGGAGA GAACCTGATT GTTCCTGGTG GAGTGAAGAC CATCGAGGCG 
AATGGCCGAA TGGTCATTCC CGGTGGCATT GATGTCAACA CTTACCTGCA GAAGCCCTCC 
CAGGGCATGA CCTCGGCTGA TGACTTCTTC CAGGGCACTA AAGCAGCGCT GGCAGGTGGA 
ACCACGATGA TCATTGACCA CGTTGTTCCT GAACCTGGGT CCAGCTTGTT GACTTCCTTT 
GAGAAATGGC ACGAAGCAGC AGACACCAAA TCCTGCTGTG ACTATTCCCT CCACGTGGAC 
ATCACAAGCT GGTATGATGG TGTTCGGGAA GAGCTGGAGG TGCTGGTGCA GGACAAAGGT 
GTCAACTCCT TCCAAGTCTA CATGGCGTAT AAGGACCTGT ACCAGATGTC TGACAGCCAG 
CTGTATGAAG CCTTCACCTT CCTTAAGGGT TTGGGAGCTG TGATCTTAGT CCATGCAGAA 
AATGGAGATT TGATAGCTCA GGAACAAAAA CGGATCCTGG AGATGGGCAT CACGGGTCCC 
GAGGGTCATG CTCTGAGCAG ACCCGAGGAG CTGGAGGCCG AGGCTGTGTT CCGGGCTATT 
GCCATTGCAG GCCGGATCAA TTGCCCTGTG TACATCACCA AGGTCATGAG CAAGAGTGCA 
GCGGACATCA TCGCACTGGC CAGGAAGAAA GGCCCTCTTG TCTTCGGTGA GCCCATAGCC 
GCCAGCCTGG GAACCGATGG CACCCACTAC TGGAGCAAGA ACTGGGCCAA GGCAGCTGCA 
TTTGTGACTT CCCCTCCCCT GAGCCCAGAC CCCACCACTC CTGACTACTT GACCTCCTTG 
CTGGCCTGTG GAGACTTGCA GGTCACAGGT AGTGGCCACT GTCCCTACAG TACTGCTCAG 
AAGGCTGTGG GCAAGGACAA CTTCACTCTG ATCCCTGAGG GTGTCAATGG TATAGAAGAG 
CGGATGACCG TTGTCTGGGA CAAGGCAGTG GCTACTGGCA AGATGGATGA GAACCAGTTT 
GTAGCCGTCA CCAGCACCAA CGCAGCCAAG ATCTTCAACC TGTACCCGAG GAAAGGTCGG 
ATCGCTGTGG GCTCCGATGC TGACGTAGTC ATCTGGGACC CAGATAAGAT GAAGACCATA 
ACAGCCAAAA GCCATAAATC AACTGTGGAG TACAACATCT TTGAGGGCAT GGAGTGCCAC 
GGCTCCCCCC TGGTGGTCAT CAGTCAGGGC AAGATTGTCT TTGAGGATGG AAACATCAGT 
GTCAGCAAGG GCATGGGCCG CTTCATCCCT CGGAAGCCAT TCCCAGAGCA TCTCTACCAG 
CGTGTCAGGA TCAGAAGCAA GGTTTTCGGG TTGCATAGTG TTTCCAGGGG CATGTACGAT 
GGGCCTGTGT ACGAGGTGCC AGCTACACCC AAACATGCTG CTCCTGCTCC TTCTGCCAAA 
TCCTCGCCTT CTAAACACCA ACCCCCACCC ATCCGGAACC TCCACCAGTC CAACTTCAGC 
TTATCAGGTG CCCAGATAGA TGACAACAAT CCAAGGCGTA CAGGCCACCG CATTGTGGCG 
CCCCCTGGTG GCCGCTCCAA CATCACCAGC CTCGGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031791.3
CDS	295..2013
Translation	MSHQGKKSIPHITSDRLLIRGGRIINDDQSFYADVYLEDGLIKQIGENLIVPGGVKTIEANGRMVIPGGIDVNTYLQKPSQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDLYQMSDSQLYEAFTFLKGLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAIAIAGRINCPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKMKTITAKSHKSTVEYNIFEGMECHGSPLVVISQGKIVFEDGNISVSKGMGRFIPRKPFPEHLYQRVRIRSKVFGLHSVSRGMYDGPVYEVPATPKHAAPAPSAKSSPSKHQPPPIRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG

Target ORF information:

RefSeq Version	NM_007765.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus collapsin response mediator protein 1 (Crmp1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007765.4

ORF Insert Sequence:

ATGTCTCATC AGGGGAAGAA GAGCATCCCG CACATCACCA GTGACCGGCT CCTCATCAGA 
GGTGGACGCA TCATCAATGA TGACCAGTCC TTCTACGCCG ATGTCTACCT AGAAGATGGA 
CTCATAAAAC AAATAGGAGA GAACCTGATT GTTCCTGGTG GAGTGAAGAC CATCGAGGCG 
AATGGCCGAA TGGTCATTCC CGGTGGCATT GATGTCAACA CTTACCTGCA GAAGCCCTCC 
CAGGGCATGA CCTCGGCTGA TGACTTCTTC CAGGGCACTA AAGCAGCGCT GGCAGGTGGA 
ACCACGATGA TCATTGACCA CGTTGTTCCT GAACCTGGGT CCAGCTTGTT GACTTCCTTT 
GAGAAATGGC ACGAAGCAGC AGACACCAAA TCCTGCTGTG ACTATTCCCT CCACGTGGAC 
ATCACAAGCT GGTATGATGG TGTTCGGGAA GAGCTGGAGG TGCTGGTGCA GGACAAAGGT 
GTCAACTCCT TCCAAGTCTA CATGGCGTAT AAGGACCTGT ACCAGATGTC TGACAGCCAG 
CTGTATGAAG CCTTCACCTT CCTTAAGGGT TTGGGAGCTG TGATCTTAGT CCATGCAGAA 
AATGGAGATT TGATAGCTCA GGAACAAAAA CGGATCCTGG AGATGGGCAT CACGGGTCCC 
GAGGGTCATG CTCTGAGCAG ACCCGAGGAG CTGGAGGCCG AGGCTGTGTT CCGGGCTATT 
GCCATTGCAG GCCGGATCAA TTGCCCTGTG TACATCACCA AGGTCATGAG CAAGAGTGCA 
GCGGACATCA TCGCACTGGC CAGGAAGAAA GGCCCTCTTG TCTTCGGTGA GCCCATAGCC 
GCCAGCCTGG GAACCGATGG CACCCACTAC TGGAGCAAGA ACTGGGCCAA GGCAGCTGCA 
TTTGTGACTT CCCCTCCCCT GAGCCCAGAC CCCACCACTC CTGACTACTT GACCTCCTTG 
CTGGCCTGTG GAGACTTGCA GGTCACAGGT AGTGGCCACT GTCCCTACAG TACTGCTCAG 
AAGGCTGTGG GCAAGGACAA CTTCACTCTG ATCCCTGAGG GTGTCAATGG TATAGAAGAG 
CGGATGACCG TTGTCTGGGA CAAGGCAGTG GCTACTGGCA AGATGGATGA GAACCAGTTT 
GTAGCCGTCA CCAGCACCAA CGCAGCCAAG ATCTTCAACC TGTACCCGAG GAAAGGTCGG 
ATCGCTGTGG GCTCCGATGC TGACGTAGTC ATCTGGGACC CAGATAAGAT GAAGACCATA 
ACAGCCAAAA GCCATAAATC AACTGTGGAG TACAACATCT TTGAGGGCAT GGAGTGCCAC 
GGCTCCCCCC TGGTGGTCAT CAGTCAGGGC AAGATTGTCT TTGAGGATGG AAACATCAGT 
GTCAGCAAGG GCATGGGCCG CTTCATCCCT CGGAAGCCAT TCCCAGAGCA TCTCTACCAG 
CGTGTCAGGA TCAGAAGCAA GGTTTTCGGG TTGCATAGTG TTTCCAGGGG CATGTACGAT 
GGGCCTGTGT ACGAGGTGCC AGCTACACCC AAACATGCTG CTCCTGCTCC TTCTGCCAAA 
TCCTCGCCTT CTAAACACCA ACCCCCACCC ATCCGGAACC TCCACCAGTC CAACTTCAGC 
TTATCAGGTG CCCAGATAGA TGACAACAAT CCAAGGCGTA CAGGCCACCG CATTGTGGCG 
CCCCCTGGTG GCCGCTCCAA CATCACCAGC CTCGGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Crmp1 ( NM_001136058.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001129530.1 Mus musculus collapsin response mediator protein 1 (Crmp1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu06297
Clone ID Related Accession (Same CDS sequence)	NM_001136058.2
Accession Version	NM_001136058.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2061bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Mus musculus(house mouse)
Product	dihydropyrimidinase-related protein 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CA321187.1, BC065046.1 and BM116580.2. On Jan 18, 2013 this sequence version replaced NM_001136058.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC065046.1, AK159049.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849383, SAMN00849384 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGAGC GGCGGCGCGC GTGGAACACG GAGGACGACC TGCCGGTGTA CCTGGCGCGG 
CCAGGCAGCG CGGCGCAGAC CCCGCGCCAG AAGTACGGCG GCATGTTCGC CGCCGTGGAG 
GGCGCCTACG AGAACAAGAC CATCGACTTC GACGCCTACA GCGTGGGCCG CCGCGGCTCC 
GCGCGCACAC CACGCAGCGC TGGCCGGCCC GACGCCGTGG GCCTGCCGTG CCCCGGCGGC 
AGCGAAGACA CGGCCAGTGA TGTGAGCGAG CCCTCGGGCT CTGCTGTCAG TTCGCCAGGC 
GATCGCGATG ACAGACCGCC AGCGTTGCGC ATCCGATGTC CTGCGCCCCG CGACCTGCCA 
CTCGGCCGGG ACAATGGCCA GAGTGACCGG CTCCTCATCA GAGGTGGACG CATCATCAAT 
GATGACCAGT CCTTCTACGC CGATGTCTAC CTAGAAGATG GACTCATAAA ACAAATAGGA 
GAGAACCTGA TTGTTCCTGG TGGAGTGAAG ACCATCGAGG CGAATGGCCG AATGGTCATT 
CCCGGTGGCA TTGATGTCAA CACTTACCTG CAGAAGCCCT CCCAGGGCAT GACCTCGGCT 
GATGACTTCT TCCAGGGCAC TAAAGCAGCG CTGGCAGGTG GAACCACGAT GATCATTGAC 
CACGTTGTTC CTGAACCTGG GTCCAGCTTG TTGACTTCCT TTGAGAAATG GCACGAAGCA 
GCAGACACCA AATCCTGCTG TGACTATTCC CTCCACGTGG ACATCACAAG CTGGTATGAT 
GGTGTTCGGG AAGAGCTGGA GGTGCTGGTG CAGGACAAAG GTGTCAACTC CTTCCAAGTC 
TACATGGCGT ATAAGGACCT GTACCAGATG TCTGACAGCC AGCTGTATGA AGCCTTCACC 
TTCCTTAAGG GTTTGGGAGC TGTGATCTTA GTCCATGCAG AAAATGGAGA TTTGATAGCT 
CAGGAACAAA AACGGATCCT GGAGATGGGC ATCACGGGTC CCGAGGGTCA TGCTCTGAGC 
AGACCCGAGG AGCTGGAGGC CGAGGCTGTG TTCCGGGCTA TTGCCATTGC AGGCCGGATC 
AATTGCCCTG TGTACATCAC CAAGGTCATG AGCAAGAGTG CAGCGGACAT CATCGCACTG 
GCCAGGAAGA AAGGCCCTCT TGTCTTCGGT GAGCCCATAG CCGCCAGCCT GGGAACCGAT 
GGCACCCACT ACTGGAGCAA GAACTGGGCC AAGGCAGCTG CATTTGTGAC TTCCCCTCCC 
CTGAGCCCAG ACCCCACCAC TCCTGACTAC TTGACCTCCT TGCTGGCCTG TGGAGACTTG 
CAGGTCACAG GTAGTGGCCA CTGTCCCTAC AGTACTGCTC AGAAGGCTGT GGGCAAGGAC 
AACTTCACTC TGATCCCTGA GGGTGTCAAT GGTATAGAAG AGCGGATGAC CGTTGTCTGG 
GACAAGGCAG TGGCTACTGG CAAGATGGAT GAGAACCAGT TTGTAGCCGT CACCAGCACC 
AACGCAGCCA AGATCTTCAA CCTGTACCCG AGGAAAGGTC GGATCGCTGT GGGCTCCGAT 
GCTGACGTAG TCATCTGGGA CCCAGATAAG ATGAAGACCA TAACAGCCAA AAGCCATAAA 
TCAACTGTGG AGTACAACAT CTTTGAGGGC ATGGAGTGCC ACGGCTCCCC CCTGGTGGTC 
ATCAGTCAGG GCAAGATTGT CTTTGAGGAT GGAAACATCA GTGTCAGCAA GGGCATGGGC 
CGCTTCATCC CTCGGAAGCC ATTCCCAGAG CATCTCTACC AGCGTGTCAG GATCAGAAGC 
AAGGTTTTCG GGTTGCATAG TGTTTCCAGG GGCATGTACG ATGGGCCTGT GTACGAGGTG 
CCAGCTACAC CCAAACATGC TGCTCCTGCT CCTTCTGCCA AATCCTCGCC TTCTAAACAC 
CAACCCCCAC CCATCCGGAA CCTCCACCAG TCCAACTTCA GCTTATCAGG TGCCCAGATA 
GATGACAACA ATCCAAGGCG TACAGGCCAC CGCATTGTGG CGCCCCCTGG TGGCCGCTCC 
AACATCACCA GCCTCGGTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129530.1
CDS	88..2148
Translation	MAERRRAWNTEDDLPVYLARPGSAAQTPRQKYGGMFAAVEGAYENKTIDFDAYSVGRRGSARTPRSAGRPDAVGLPCPGGSEDTASDVSEPSGSAVSSPGDRDDRPPALRIRCPAPRDLPLGRDNGQSDRLLIRGGRIINDDQSFYADVYLEDGLIKQIGENLIVPGGVKTIEANGRMVIPGGIDVNTYLQKPSQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDLYQMSDSQLYEAFTFLKGLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAIAIAGRINCPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKMKTITAKSHKSTVEYNIFEGMECHGSPLVVISQGKIVFEDGNISVSKGMGRFIPRKPFPEHLYQRVRIRSKVFGLHSVSRGMYDGPVYEVPATPKHAAPAPSAKSSPSKHQPPPIRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG

Target ORF information:

RefSeq Version	NM_001136058.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus collapsin response mediator protein 1 (Crmp1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001136058.2

ORF Insert Sequence:

ATGGCGGAGC GGCGGCGCGC GTGGAACACG GAGGACGACC TGCCGGTGTA CCTGGCGCGG 
CCAGGCAGCG CGGCGCAGAC CCCGCGCCAG AAGTACGGCG GCATGTTCGC CGCCGTGGAG 
GGCGCCTACG AGAACAAGAC CATCGACTTC GACGCCTACA GCGTGGGCCG CCGCGGCTCC 
GCGCGCACAC CACGCAGCGC TGGCCGGCCC GACGCCGTGG GCCTGCCGTG CCCCGGCGGC 
AGCGAAGACA CGGCCAGTGA TGTGAGCGAG CCCTCGGGCT CTGCTGTCAG TTCGCCAGGC 
GATCGCGATG ACAGACCGCC AGCGTTGCGC ATCCGATGTC CTGCGCCCCG CGACCTGCCA 
CTCGGCCGGG ACAATGGCCA GAGTGACCGG CTCCTCATCA GAGGTGGACG CATCATCAAT 
GATGACCAGT CCTTCTACGC CGATGTCTAC CTAGAAGATG GACTCATAAA ACAAATAGGA 
GAGAACCTGA TTGTTCCTGG TGGAGTGAAG ACCATCGAGG CGAATGGCCG AATGGTCATT 
CCCGGTGGCA TTGATGTCAA CACTTACCTG CAGAAGCCCT CCCAGGGCAT GACCTCGGCT 
GATGACTTCT TCCAGGGCAC TAAAGCAGCG CTGGCAGGTG GAACCACGAT GATCATTGAC 
CACGTTGTTC CTGAACCTGG GTCCAGCTTG TTGACTTCCT TTGAGAAATG GCACGAAGCA 
GCAGACACCA AATCCTGCTG TGACTATTCC CTCCACGTGG ACATCACAAG CTGGTATGAT 
GGTGTTCGGG AAGAGCTGGA GGTGCTGGTG CAGGACAAAG GTGTCAACTC CTTCCAAGTC 
TACATGGCGT ATAAGGACCT GTACCAGATG TCTGACAGCC AGCTGTATGA AGCCTTCACC 
TTCCTTAAGG GTTTGGGAGC TGTGATCTTA GTCCATGCAG AAAATGGAGA TTTGATAGCT 
CAGGAACAAA AACGGATCCT GGAGATGGGC ATCACGGGTC CCGAGGGTCA TGCTCTGAGC 
AGACCCGAGG AGCTGGAGGC CGAGGCTGTG TTCCGGGCTA TTGCCATTGC AGGCCGGATC 
AATTGCCCTG TGTACATCAC CAAGGTCATG AGCAAGAGTG CAGCGGACAT CATCGCACTG 
GCCAGGAAGA AAGGCCCTCT TGTCTTCGGT GAGCCCATAG CCGCCAGCCT GGGAACCGAT 
GGCACCCACT ACTGGAGCAA GAACTGGGCC AAGGCAGCTG CATTTGTGAC TTCCCCTCCC 
CTGAGCCCAG ACCCCACCAC TCCTGACTAC TTGACCTCCT TGCTGGCCTG TGGAGACTTG 
CAGGTCACAG GTAGTGGCCA CTGTCCCTAC AGTACTGCTC AGAAGGCTGT GGGCAAGGAC 
AACTTCACTC TGATCCCTGA GGGTGTCAAT GGTATAGAAG AGCGGATGAC CGTTGTCTGG 
GACAAGGCAG TGGCTACTGG CAAGATGGAT GAGAACCAGT TTGTAGCCGT CACCAGCACC 
AACGCAGCCA AGATCTTCAA CCTGTACCCG AGGAAAGGTC GGATCGCTGT GGGCTCCGAT 
GCTGACGTAG TCATCTGGGA CCCAGATAAG ATGAAGACCA TAACAGCCAA AAGCCATAAA 
TCAACTGTGG AGTACAACAT CTTTGAGGGC ATGGAGTGCC ACGGCTCCCC CCTGGTGGTC 
ATCAGTCAGG GCAAGATTGT CTTTGAGGAT GGAAACATCA GTGTCAGCAA GGGCATGGGC 
CGCTTCATCC CTCGGAAGCC ATTCCCAGAG CATCTCTACC AGCGTGTCAG GATCAGAAGC 
AAGGTTTTCG GGTTGCATAG TGTTTCCAGG GGCATGTACG ATGGGCCTGT GTACGAGGTG 
CCAGCTACAC CCAAACATGC TGCTCCTGCT CCTTCTGCCA AATCCTCGCC TTCTAAACAC 
CAACCCCCAC CCATCCGGAA CCTCCACCAG TCCAACTTCA GCTTATCAGG TGCCCAGATA 
GATGACAACA ATCCAAGGCG TACAGGCCAC CGCATTGTGG CGCCCCCTGG TGGCCGCTCC 
AACATCACCA GCCTCGGTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A functional coupling between CRMP1 and Na
Journal of cell science130(8)1393-1403(2017 04)
Yamane M,Yamashita N,Hida T,Kamiya Y,Nakamura F,Kolattukudy P,Goshima Y

CRMP1 and CRMP4 are required for proper orientation of dendrites of cerebral pyramidal neurons in the developing mouse brain.
Brain research1655161-167(2017 01)
Takaya R,Nagai J,Piao W,Niisato E,Nakabayashi T,Yamazaki Y,Nakamura F,Yamashita N,Kolattukudy P,Goshima Y,Ohshima T

CRMP1 and CRMP2 have synergistic but distinct roles in dendritic development.
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Crmp1 cDNA ORF clone, Mus musculus(house mouse)

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Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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