Crkl cDNA ORF clone, Mus musculus(house mouse)

The following Crkl gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Crkl cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu07884 NM_001277231.1
Latest version!
Mus musculus v-crk avian sarcoma virus CT10 oncogene homolog-like (Crkl), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $69.30
$99.00
OMu00758 NM_007764.5
Latest version!
Mus musculus v-crk avian sarcoma virus CT10 oncogene homolog-like (Crkl), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 5-7 $188.30
$269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    CloneID OMu07884
    Clone ID Related Accession (Same CDS sequence) NM_001277231.1
    Accession Version NM_001277231.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 327bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-10-24
    Organism Mus musculus(house mouse)
    Product crk-like protein isoform 2
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK052315.1, CA328740.1, AK048641.1, AW541802.2, BF453354.1, BF464821.1 and BY471344.1. Transcript Variant: This variant (2) lacks an exon in the coding region, which results in a frameshift and an early stop codon compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660825.62902.1, SRR7652917.394701.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    ATGTCCTCCG CCAGGTTTGA TTCTTCAGAC CGCTCTGCCT GGTACATGGG GCCAGTGACT 
    CGCCAGGAGG CGCAGACTCG TCTCCAAGGC CAGCGCCATG GCATGTTCCT AGTCCGGGAC
    TCATCTACCT GCCCCGGGGA CTATGTACTG TCCGTGTCCG AGAACTCGCG TGTCTCGCAC
    TACATCATCA ACTCCCTGCC CAACCGCCGC TTTAAGATCG GGGACCAGGA GTTTGACCAT
    TTGCCGGCCT TGTTAGAGTT CTACAAGATC CACTACCTGG ACACTACCAC CTTAATCGAA
    CCGGCGCCCA GGTTGGTGAC ATTGTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001264160.1
    CDS494..820
    Translation

    Target ORF information:

    RefSeq Version NM_001277231.1
    Organism Mus musculus(house mouse)
    Definition Mus musculus v-crk avian sarcoma virus CT10 oncogene homolog-like (Crkl), transcript variant 2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001277231.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    ATGTCCTCCG CCAGGTTTGA TTCTTCAGAC CGCTCTGCCT GGTACATGGG GCCAGTGACT 
    CGCCAGGAGG CGCAGACTCG TCTCCAAGGC CAGCGCCATG GCATGTTCCT AGTCCGGGAC
    TCATCTACCT GCCCCGGGGA CTATGTACTG TCCGTGTCCG AGAACTCGCG TGTCTCGCAC
    TACATCATCA ACTCCCTGCC CAACCGCCGC TTTAAGATCG GGGACCAGGA GTTTGACCAT
    TTGCCGGCCT TGTTAGAGTT CTACAAGATC CACTACCTGG ACACTACCAC CTTAATCGAA
    CCGGCGCCCA GGTTGGTGAC ATTGTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OMu00758
    Clone ID Related Accession (Same CDS sequence) NM_007764.5
    Accession Version NM_007764.5 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 912bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-27
    Organism Mus musculus(house mouse)
    Product crk-like protein isoform 1
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK052315.1, AK048641.1, AW541802.2, BF453354.1, BF464821.1 and BY471344.1. On Mar 23, 2013 this sequence version replaced NM_007764.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK052315.1, SRR1660815.35856.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGTCCTCCG CCAGGTTTGA TTCTTCAGAC CGCTCTGCCT GGTACATGGG GCCAGTGACT 
    CGCCAGGAGG CGCAGACTCG TCTCCAAGGC CAGCGCCATG GCATGTTCCT AGTCCGGGAC
    TCATCTACCT GCCCCGGGGA CTATGTACTG TCCGTGTCCG AGAACTCGCG TGTCTCGCAC
    TACATCATCA ACTCCCTGCC CAACCGCCGC TTTAAGATCG GGGACCAGGA GTTTGACCAT
    TTGCCGGCCT TGTTAGAGTT CTACAAGATC CACTACCTGG ACACTACCAC CTTAATCGAA
    CCGGCGCCCA GGTACCCAAG CCCACCAGTG GGTTCTGTCT CAGCACCCAA CTTACCTACA
    GCAGAAGAAA ATCTGGAATA TGTACGGACC CTTTATGATT TTCCTGGGAA TGATGCTGAA
    GACCTACCCT TTAAAAAGGG CGAGCTTCTA GTGATAATAG AAAAGCCTGA AGAGCAGTGG
    TGGAGTGCCC GCAACAAGGA CGGCCGGGTT GGGATGATTC CTGTCCCTTA CGTTGAAAAG
    CTTGTGAGGT CTTCGCCACA TGGAAAGCAT GGAAATAGGA ATTCTAACAG TTATGGCATC
    CCAGAACCTG CTCATGCGTA TGCTCAACCT CAGACCACAA CTCCTCTACC TACAGTTGCC
    AGTACTCCTG GGGCAGCGAT CAACCCTTTG CCATCCACAC AGAATGGACC TGTCTTTGCA
    AAAGCAATCC AGAAGAGAGT ACCTTGTGCT TATGACAAGA CTGCCTTGGC ATTGGAGGTT
    GGTGACATTG TGAAAGTCAC AAGGATGAAT ATCAATGGCC AATGGGAAGG CGAGGTGAAT
    GGGCGCAAGG GGCTTTTCCC CTTCACACAT GTTAAAATCT TTGACCCTCA GAACCCCGAT
    GACAACGAGT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_031790.2
    CDS494..1405
    Translation

    Target ORF information:

    RefSeq Version NM_007764.5
    Organism Mus musculus(house mouse)
    Definition Mus musculus v-crk avian sarcoma virus CT10 oncogene homolog-like (Crkl), transcript variant 1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_007764.5

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGTCCTCCG CCAGGTTTGA TTCTTCAGAC CGCTCTGCCT GGTACATGGG GCCAGTGACT 
    CGCCAGGAGG CGCAGACTCG TCTCCAAGGC CAGCGCCATG GCATGTTCCT AGTCCGGGAC
    TCATCTACCT GCCCCGGGGA CTATGTACTG TCCGTGTCCG AGAACTCGCG TGTCTCGCAC
    TACATCATCA ACTCCCTGCC CAACCGCCGC TTTAAGATCG GGGACCAGGA GTTTGACCAT
    TTGCCGGCCT TGTTAGAGTT CTACAAGATC CACTACCTGG ACACTACCAC CTTAATCGAA
    CCGGCGCCCA GGTACCCAAG CCCACCAGTG GGTTCTGTCT CAGCACCCAA CTTACCTACA
    GCAGAAGAAA ATCTGGAATA TGTACGGACC CTTTATGATT TTCCTGGGAA TGATGCTGAA
    GACCTACCCT TTAAAAAGGG CGAGCTTCTA GTGATAATAG AAAAGCCTGA AGAGCAGTGG
    TGGAGTGCCC GCAACAAGGA CGGCCGGGTT GGGATGATTC CTGTCCCTTA CGTTGAAAAG
    CTTGTGAGGT CTTCGCCACA TGGAAAGCAT GGAAATAGGA ATTCTAACAG TTATGGCATC
    CCAGAACCTG CTCATGCGTA TGCTCAACCT CAGACCACAA CTCCTCTACC TACAGTTGCC
    AGTACTCCTG GGGCAGCGAT CAACCCTTTG CCATCCACAC AGAATGGACC TGTCTTTGCA
    AAAGCAATCC AGAAGAGAGT ACCTTGTGCT TATGACAAGA CTGCCTTGGC ATTGGAGGTT
    GGTGACATTG TGAAAGTCAC AAGGATGAAT ATCAATGGCC AATGGGAAGG CGAGGTGAAT
    GGGCGCAAGG GGCTTTTCCC CTTCACACAT GTTAAAATCT TTGACCCTCA GAACCCCGAT
    GACAACGAGT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

  • PubMed

    Crk proteins transduce FGF signaling to promote lens fiber cell elongation.
    eLife7(2018 Jan)
    Collins TN,Mao Y,Li H,Bouaziz M,Hong A,Feng GS,Wang F,Quilliam LA,Chen L,Park T,Curran T,Zhang X


    Murine model indicates 22q11.2 signaling adaptor
    Proceedings of the National Academy of Sciences of the United States of America114(19)4981-4986(2017 May)
    Haller M,Mo Q,Imamoto A,Lamb DJ


    Genetic Drivers of Kidney Defects in the DiGeorge Syndrome.
    The New England journal of medicine376(8)742-754(2017 02)
    Lopez-Rivera E,Liu YP,Verbitsky M,Anderson BR,Capone VP,Otto EA,Yan Z,Mitrotti A,Martino J,Steers NJ,Fasel DA,Vukojevic K,Deng R,Racedo SE,Liu Q,Werth M,Westland R,Vivante A,Makar GS,Bodria M,Sampson MG,Gillies CE,Vega-Warner V,Maiorana M,Petrey DS,Honig B,Lozanovski VJ,Salomon R,Heidet L,Carpentier W,Gaillard D,Carrea A,Gesualdo L,Cusi D,Izzi C,Scolari F,van Wijk JA,Arapovic A,Saraga-Babic M,Saraga M,Kunac N,Samii A,McDonald-McGinn DM,Crowley TB,Zackai EH,Drozdz D,Miklaszewska M,Tkaczyk M,Sikora P,Szczepanska M,Mizerska-Wasiak M,Krzemien G,Szmigielska A,Zaniew M,Darlow JM,Puri P,Barton D,Casolari E,Furth SL,Warady BA,Gucev Z,Hakonarson H,Flogelova H,Tasic V,Latos-Bielenska A,Materna-Kiryluk A,Allegri L,Wong CS,Drummond IA,D'Agati V,Imamoto A,Barasch JM,Hildebrandt F,Kiryluk K,Lifton RP,Morrow BE,Jeanpierre C,Papaioannou VE,Ghiggeri GM,Gharavi AG,Katsanis N,Sanna-Cherchi S


    BCR/ABL P190 transgenic mice develop leukemia in the absence of Crkl.
    Oncogene21(20)3225-31(2002 May)
    Hemmeryckx B,Reichert A,Watanabe M,Kaartinen V,de Jong R,Pattengale PK,Groffen J,Heisterkamp N