Crabp2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Crabp2
Entrez Gene ID	12904
Full Name	cellular retinoic acid binding protein II
Synonyms	AI893628,Crabp-2,CrabpII
General protein information	Preferred Names cellular retinoic acid binding protein II Names cellular retinoic acid-binding protein 2 CRABP-II
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 3 Map Location: 3 F1\|3

mRNA and Protein(s)

mRNA	Protein	Name
NM_007759.2	NP_031785.1	cellular retinoic acid-binding protein 2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	CRABP2	XP_854915.1
Danio rerio (zebrafish)	crabp2b	NP_001012501.2
Pan troglodytes (chimpanzee)	CRABP2	XP_001166367.1
Danio rerio (zebrafish)	LOC100332539	XP_002664864.1
Bos taurus (cattle)	CRABP2	NP_001008670.1
Mus musculus (house mouse)	Crabp2	NP_031785.1
Danio rerio (zebrafish)	crabp2a	NP_878279.1
Xenopus tropicalis (tropical clawed frog)	crabp2	NP_001006863.1
Homo sapiens (human)	CRABP2	NP_001186652.1
	CRABP2	XP_001116699.1

Gene Ontology
Bibliography

Related articles in PubMed

TBR2 antagonizes retinoic acid dependent neuronal differentiation by repressing Zfp423 during corticogenesis.
Massimino L, Flores-Garcia L, Di Stefano B, Colasante G, Icoresi-Mazzeo C, Zaghi M, Hamilton BA, Sessa A
Developmental biology(2018 Jan)

Genetic Labeling of Nuclei-Specific Thalamocortical Neurons Reveals Putative Sensory-Modality Specific Genes.
Gezelius H, Moreno-Juan V, Mezzera C, Thakurela S, Rodr?guez-Malmierca LM, Pistolic J, Benes V, Tiwari VK, L?pez-Bendito G
Cerebral cortex (New York, N.Y. : 1991)27(11)5054-5069(2017 Nov)

Divergent Hox Coding and Evasion of Retinoid Signaling Specifies Motor Neurons Innervating Digit Muscles.
Mendelsohn AI, Dasen JS, Jessell TM
Neuron93(4)792-805.e4(2017 Feb)

RNA-binding protein HuR regulates nuclear import of protein.
Zhang W, Vreeland AC, Noy N
Journal of cell science129(21)4025-4033(2016 11)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The anticarcinogenic activities of CRABP2 are mediated by both HuR and RAR.
Title: Cellular retinoic acid-binding protein 2 inhibits tumor growth by two distinct mechanisms.

Results show that acetylation status of CRABPII directly influences embryonic stem cell differentiation in response to retinoic acid.
Title: SIRT1-mediated deacetylation of CRABPII regulates cellular retinoic acid signaling and modulates embryonic stem cell differentiation.

CRABP2 controls mRNA stabilization by HuR.
Title: Transcript stabilization by the RNA-binding protein HuR is regulated by cellular retinoic acid-binding protein 2.

all three proteins (RDH10, RALDH2, and CRABP2) appeared to be required for ATRA production induced by activation of PPARgamma
Title: RDH10, RALDH2, and CRABP2 are required components of PPAR?-directed ATRA synthesis and signaling in human dendritic cells.

CRABP2 promotes myoblast differentiation and is modulated by the transcription factors MyoD and Sp1 in C2C12 cells.
Title: CRABP2 promotes myoblast differentiation and is modulated by the transcription factors MyoD and Sp1 in C2C12 cells.

The following Crabp2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Crabp2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu19667	NM_007759.2 Latest version!	Mus musculus cellular retinoic acid binding protein II (Crabp2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Crabp2 ( NM_007759.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031785.1 Mus musculus cellular retinoic acid binding protein II (Crabp2), mRNA.

Price & Availability↑

CloneID	OMu19667
Clone ID Related Accession (Same CDS sequence)	NM_007759.2
Accession Version	NM_007759.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 417bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-03
Organism	Mus musculus(house mouse)
Product	cellular retinoic acid-binding protein 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC158233.2. On Nov 17, 2006 this sequence version replaced NM_007759.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AI893628.1, CB202869.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGCCTAACT TTTCTGGCAA CTGGAAGATC ATCCGATCGG AAAACTTTGA GGAAATGCTA 
AAAGCTCTGG GGGTGAACAT GATGATGAGG AAGATCGCTG TGGCTGCAGC CTCCAAGCCA 
GCAGTCGAGA TCAAACAGGA GAATGACACT TTCTACATCA AAACCTCCAC CACTGTGCGA 
ACCACGGAGA TTAACTTCAA GATCGGGGAG GAATTTGAGG AGCAGACCGT GGATGGGAGA 
CCCTGTAAGA GTTTGGTGAA ATGGGAGAGT GGAAACAAAA TGGTGTGCGA GCAGAGGCTT 
CTGAAGGGGG AGGGCCCCAA GACCTCCTGG AGCCGAGAAC TGACCAATGA TGGAGAGCTG 
ATCCTGACAA TGACAGCAGA TGACGTTGTG TGCACCAGGG TCTACGTCCG AGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031785.1
CDS	149..565
Translation	MPNFSGNWKIIRSENFEEMLKALGVNMMMRKIAVAAASKPAVEIKQENDTFYIKTSTTVRTTEINFKIGEEFEEQTVDGRPCKSLVKWESGNKMVCEQRLLKGEGPKTSWSRELTNDGELILTMTADDVVCTRVYVRE

Target ORF information:

RefSeq Version	NM_007759.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus cellular retinoic acid binding protein II (Crabp2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007759.2

ORF Insert Sequence:

ATGCCTAACT TTTCTGGCAA CTGGAAGATC ATCCGATCGG AAAACTTTGA GGAAATGCTA 
AAAGCTCTGG GGGTGAACAT GATGATGAGG AAGATCGCTG TGGCTGCAGC CTCCAAGCCA 
GCAGTCGAGA TCAAACAGGA GAATGACACT TTCTACATCA AAACCTCCAC CACTGTGCGA 
ACCACGGAGA TTAACTTCAA GATCGGGGAG GAATTTGAGG AGCAGACCGT GGATGGGAGA 
CCCTGTAAGA GTTTGGTGAA ATGGGAGAGT GGAAACAAAA TGGTGTGCGA GCAGAGGCTT 
CTGAAGGGGG AGGGCCCCAA GACCTCCTGG AGCCGAGAAC TGACCAATGA TGGAGAGCTG 
ATCCTGACAA TGACAGCAGA TGACGTTGTG TGCACCAGGG TCTACGTCCG AGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

TBR2 antagonizes retinoic acid dependent neuronal differentiation by repressing Zfp423 during corticogenesis.
Developmental biology(2018 Jan)
Massimino L,Flores-Garcia L,Di Stefano B,Colasante G,Icoresi-Mazzeo C,Zaghi M,Hamilton BA,Sessa A

Genetic Labeling of Nuclei-Specific Thalamocortical Neurons Reveals Putative Sensory-Modality Specific Genes.
Cerebral cortex (New York, N.Y. : 1991)27(11)5054-5069(2017 Nov)
Gezelius H,Moreno-Juan V,Mezzera C,Thakurela S,Rodr?guez-Malmierca LM,Pistolic J,Benes V,Tiwari VK,L?pez-Bendito G

Divergent Hox Coding and Evasion of Retinoid Signaling Specifies Motor Neurons Innervating Digit Muscles.
Neuron93(4)792-805.e4(2017 Feb)
Mendelsohn AI,Dasen JS,Jessell TM

RNA-binding protein HuR regulates nuclear import of protein.
Journal of cell science129(21)4025-4033(2016 11)
Zhang W,Vreeland AC,Noy N