Abcc2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Abcc2
Entrez Gene ID	12780
Full Name	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Synonyms	AI173996,Abc30,Cmoat,Mrp2,cMRP
General protein information	Preferred Names ATP-binding cassette, sub-family C (CFTR/MRP), member 2 Names canalicular multispecific organic anion transporter 1 ATP-binding cassette sub-family C member 2 multidrug resistance protein 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 19 Map Location: 19 C3\|19 36.67 cM
Summary	The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the canalicular surface of the hepatocyte and in biliary transport, and appears to contribute to drug resistance in mammalian cells. Several different mutations in the human gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. Alternative splice variants have been observed for this gene; however, they have not been fully described. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006526625.4	XP_006526688.1	canalicular multispecific organic anion transporter 1 isoform X1
NM_013806.2	NP_038834.2	canalicular multispecific organic anion transporter 1
XM_006526625.3	XP_006526688.1	canalicular multispecific organic anion transporter 1 isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Abcc2	NP_038834.2
Arabidopsis thaliana (thale cress)	MRP2	NP_001189675.1
Danio rerio (zebrafish)	abcc2	NP_956883.2
Arabidopsis thaliana (thale cress)	MRP12	NP_174331.2
Homo sapiens (human)	ABCC2	NP_000383.1
	ABCC2	NP_001028019.1
Arabidopsis thaliana (thale cress)	MRP1	NP_174329.1
Canis lupus familiaris (dog)	ABCC2	NP_001003081.1
Gallus gallus (chicken)	ABCC2	XP_421698.4
Bos taurus (cattle)	ABCC2	XP_002698533.1
Rattus norvegicus (Norway rat)	Abcc2	NP_036965.1
Arabidopsis thaliana (thale cress)	MRP13	NP_174330.3
Xenopus tropicalis (tropical clawed frog)	abcc2	XP_004915926.1

Gene Ontology
Bibliography

Related articles in PubMed

Circadian Clock Is Involved in Regulation of Hepatobiliary Transport Mediated by Multidrug Resistance-Associated Protein 2.
Oh JH, Lee JH, Han DH, Cho S, Lee YJ
Journal of pharmaceutical sciences106(9)2491-2498(2017 Sep)

CFTR-associated ligand is a negative regulator of Mrp2 expression.
Li M, Soroka CJ, Harry K, Boyer JL
American journal of physiology. Cell physiology312(1)C40-C46(2017 Jan)

Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors.
Kaminski MM, Tosic J, Kresbach C, Engel H, Klockenbusch J, M?ller AL, Pichler R, Grahammer F, Kretz O, Huber TB, Walz G, Arnold SJ, Lienkamp SS
Nature cell biology18(12)1269-1280(2016 Dec)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Biotinylation and streptavidin pull-down assays confirmed that CAL dramatically reduces the expression level of total and cell surface Mrp2 in Huh-7 cells. Our findings suggest that CAL interacts with Mrp2 and is a negative regulator of Mrp2 expression.
Title: CFTR-associated ligand is a negative regulator of Mrp2 expression.

Deficiency in Mrp2 lowers platinum excretion and increases susceptibility to kidney injury, which can be rescued by the human MRP2 ortholog.
Title: Transgenic expression of the human MRP2 transporter reduces cisplatin accumulation and nephrotoxicity in Mrp2-null mice.

In Bcrp1;Mrp2;Mrp3(-/-), but not Bcrp1;Mdr1a/b;Mrp(-/-) mice.
Title: Bcrp1;Mdr1a/b;Mrp2 combination knockout mice: altered disposition of the dietary carcinogen PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) and its genotoxic metabolites.

Cd or H(2)O(2) exposure increased the expression of key transport genes, Mrp1 and Mrp2, in WT cells but not in metallothionein-null cells.
Title: Metallothionein blocks oxidative DNA damage in vitro.

hepatic transporters Ntcp and Mrp2 are downregulated in rodent models of necrotizing enterocolitis
Title: The hepatic bile acid transporters Ntcp and Mrp2 are downregulated in experimental necrotizing enterocolitis.

The following Abcc2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Abcc2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu55214	XM_006526625.4 Latest version!	Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (Abcc2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$727.30 $1039.00
OMu21658	NM_013806.2 Latest version!	Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (Abcc2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$811.30 $1159.00
View Old Accession Versions >>
OMu55214	XM_006526625.3	Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (Abcc2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$727.30 $1039.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Abcc2 ( XM_006526625.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006526688.1 Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (Abcc2), transcript variant X1, mRNA.

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CloneID	OMu55214
Clone ID Related Accession (Same CDS sequence)	XM_006526625.4 , XM_006526625.3
Accession Version	XM_006526625.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4488bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	canalicular multispecific organic anion transporter 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000085.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006526625.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGTGG CAGCGCTGAG TCAGAGCAAG AGGTACAGAA AAACAAAGGA GCTCAAACCA 
GTGTTCGTTG TGTGTCTTCT TATTTTAGCA GCCATAGACC TGTCTCTTGC ACTCACAGAA 
GATACTGGAC AAGCCACAAT TCCTCCTGTT AAATATACAA ATCCAATTCT CTACCTATGC 
ACTTGGCTCC TGGTGTTGGT GATCCAACAC TGCAGGCAAT GCTGTATACA GAAGAATTCT 
TGGTTCCTGT CCATGTTCTG GATTCTCTCT CTATTATGTG GCATATTCCA GTTTCAGACT 
CTGATACGAG CACTCCTGCA GGATAGCAAG TCCAACATGA CCTATTCCTG CCTGTTCTTC 
GTCTCCTATG GTTTCCAGAT TGTCATTTTG ATCCTTTCAG CCTTTTCAGA ATCAAGCGAC 
TCAACACACG CCCCATCAGC TACAGCTTCA TTTCTGAGTA GCGTTACGTT TAGTTGGTAT 
GACAGCACTG TTCTGAAAGG TTACAAGCAT CCATTGACAA TAGAAGATGT GTGGGATATT 
GAAGAAAATC TTAAAGCCAA GTCACTCACC AGCAAGTTTA AGACGATCAT GACAAAGGAC 
CTGCAGAAAG CCAGGCAGGC TCTTCAGAGG CGGCTGAAGA AGTCCCAGCA GAGCCCTGAG 
GGCACGTCAC ACGGATTGAC CAAGAAGCAG AGTCAGAGCC AAGATGTCCT TGTCCTGGAA 
GACTCGAAAA AGAAGAAAAA GAAGTCTGAG GCCACCAAAG ACTTTCCCAA ATCCTGGTTG 
GTGAAGGCTC TCTTCAAAAC GTTCTACGTG GTGATCCTGA AGTCATTTAT TCTGAAATTA 
GCACATGATA TTCTTTTGTT TCTGAATCCT CAGCTGCTGA AATTTCTCAT TGGCTTCGTG 
AAAGACCCTG ACTCATATCC GTGGGTTGGA TATATCTATG CAATCCTAAT GTTCTCTGTG 
ACTCTCATCC AGTCTTTCTT CCTTCAGTGT TATTTTCAAT TTTGTTTTGT GTTGGGAATG 
ACTGTACGGA CAACCATCAT AGCTTCCGTA TATAAGAAGG CACTAACCCT ATCTAACTTG 
GCTAGGAGGC AGTACACGAT TGGAGAGACG GTGAACTTGA TGTCTGTAGA TTCCCAGAAG 
CTAATGGACG TGACCAACTA CATACACTTG CTGTGGTCCA GTGTTTTACA GATTGCTTTG 
TCCATTTTCT TCCTGTGGAG AGAGTTGGGA CCTTCGATTT TAGCAGGTGT TGGGCTTATG 
GTTCTCCTGG TCCCAGTTAA TGGCGTCCTG GCTACCAAGA TCAGGAAAAT TCAGGTCCAG 
AATATGAAGA ATAAAGACAA ACGCTTAAAA ATCATGAATG AGATTCTTAG TGGGATTAAG 
ATCCTGAAAT ACTTTGCCTG GGAACCTTCC TTTAAAGAGC AAGTGAACAG CATTCGGAAG 
AAAGAACTCA GGAACTTGCT GCGCTTCAGC CAGCTGCAGA CGATTTTGAT TTTCATCTTA 
CACCTAACTC CAACCCTGGT GTCCGTGATC ACATTTTCTG TTTACGTCCT GGTGGATAGT 
CAAAATGTTT TGAACGCGGA GAAGGCTTTC ACCTCCATCA CCCTCTTCAA TATCCTGCGC 
TTTCCTCTGG CCATGCTTCC CATGGTGATC TCTTCAGTCA TCCAGGCCAG CGTCTCTGTA 
GACCGGCTGG AGCAGTACCT GGGAAGCGAT GATCTGGACT TGTCTGCCAT TCGCCATGTC 
TGCCATTTTG ATAAAGCTGT GCAGTTCTCA GAAGCCTCTT TTACTTGGGA CCGGGACTTG 
GAAGCCACAA TCCAAGATGT GAACCTGGAC ATAAAACCAG GCCAACTGGT GGCTGTGGTG 
GGCACTGTAG GCTCTGGGAA GTCCTCTTTG ATATCAGCCA TGCTGGGAGA AATGGAGAAT 
GTCCATGGGC ATATCACCAT CAAGGGCTCC ATAGCCTACG TCCCTCAGCA GGCCTGGATT 
CAGAACGGGA CCATCAAAGA TAACATCCTG TTTGGGTCAG AATACGATGA AAAGAAGTAC 
CAGCGAGTTA TCGAAGCGTG CGCTCTCCTC CCAGACTTGG AAATGTTGCC TGGAGGAGAC 
ATGGCTGAGA TCGGAGAGAA GGGTATAAAT CTCAGTGGCG GTCAGAAGCA TCGAGTCAGC 
CTGGCCCGGG CCACCTATCA AGATGCAGAC ATCTATATTC TAGACGACCC CCTGTCGGCT 
GTGGACACTC ACGTGGGAAA ACACATTTTC AACAAGGTTG TGGGCCCCAA TGGCCTGCTG 
AGCGGCAAGA CTCGGATCTT GGTTACACAT GGCATTCACT TCCTTCCCCA AGTGGATGAG 
ATTGTCGTTC TGGGGAAAGG CACCATCTTA GAGAAGGGAT CCTATAGTGA CCTGATGGAC 
AAGAAAGGAG TGTTCGCTAA GAACTGGAAG ACATTCATGA AGCATTCGGG ACCTGAAGGA 
GAGGCTACAG TCGATAACGA CAGTGAGGAA GAGGATGGTG ACTGTGGGCT GATCCCAACT 
GTGGAGGAAA TTCCTGACGA TGCAGCTTCC TTGACCATGA GAAGGGAGAA CAGCCTTCGC 
CGAACACTGA GCCGCAGCTC TAGGTCCGGC AGCAGGCGTG GGAAGTCCCT CAAAAGCTCC 
TTGAAAATTA AAAGTGTGAA TGCCTTGAAT AAGAAGGAGG AAGTAGTGAA AGGACAAAAA 
CTAATTAAGA AGGAATTTGT GGAAACTGGG AAGGTAAAGT TCTCCATCTA CCTGAAATAT 
CTGCAGGCGG TAGGATGGTG GTCCCTGCTC TTCATCGTCA TCTTCTACGT ATTGAACTAT 
GTGGCTTTTA TTGGCACTAA CCTCTGGCTG AGTGCTTGGA CCAGTGACTC TGAAAAACAG 
AATGGGACCG ACAATTCACC TTCTCAGAGG GACATGAGAA TCGGGGTCTT TGGAGCTCTG 
GGAATAGCAC AAGGTATATT TTTGCTTAGT TCAAGTCTAT GGAGTATATA TGCTTGCAGA 
AATGCATCCA AAACTTTGCA CAGGCAGCTG TTAACCAACA TTCTCCGCGC ACCCATGAGT 
TTTTTTGACA CAACTCCCAC AGGCCGGATT GTGAACAGAT TTGCCGGGGA TATTTCTACG 
GTGGACGACA CACTCCCCCA GACTTTGCGA AGCTGGCTGC TGTGTTTCTT CGGCATAGTT 
AGCACTCTCG TGATGATCTG CATGGCCACC CCCATCTTCA TCATCATCAT CATCCCTCTC 
AGCATTCTCT ATGTATCTGT GCAGGTGTTT TATGTGGCTA CATCCCGCCA GCTGAGACGG 
CTGGATTCTG TCACCAAATC TCCGATCTAT TCTCACTTTA GTGAGACTGT CTCTGGTTTG 
CCTGTTATTC GGGCCTTTGA GCACCAGCAG AGATTTCTAG CAAACAGTGA GAAGCAGATT 
GACACCAACC AGAAATGCGT CTTTTCCTGG ATTACCTCCA ACCGGTGGCT TGCCATTCGC 
CTGGAGCTGG TTGGAAACCT GATTGTCTTC TGCTCGGCCT TGCTTCTGGT TATTTATAAG 
AATTCCTTAA CCGGGGACAC TGTGGGCTTT GTTCTGTCCA ACGCCCTCAA CATCACACAA 
ACCCTGAACT GGCTAGTGAG GATGACGTCA GAAGTAGAGA CCAACATCGT GGCTGTTGAG 
CGAATAAATG AATACATAAA TGTGGATAAT GAGGCGCCGT GGGTGACCGA CAAGAAGCCT 
CCGGCAGATT GGCCCAAAAA AGGTGAGATC CAGTTCAACA ACTATCAAGT GCGGTATCGG 
CCGGAGCTGG ATCTGGTCCT GAAAGGGATT ACTTGTAACA TCAAGAGCAC CGAGAAGGTC 
GGTGTGGTGG GCAGGACCGG AGCTGGAAAA TCATCCCTCA CAAACTGCCT CTTCAGAATC 
TTAGAGTCTG CAGGTGGCCA GATCATCATT GATGGGATTG ATATTGCCTC CATTGGACTG 
CACGACCTTC GAGGGAGACT GACCATCATT CCCCAGGACC CCATTTTGTT CTCTGGGAAT 
CTGAGGATGA ATCTCGACCC TTTCAACAAA TACTCGGATG AGGAGATCTG GAGGGCCCTG 
GAATTGGCTC ATCTCAAATC CTTTGTGGCT GGCCTGCAAC TTGGGTTGCT CCATGAAGTG 
ACAGAGGGCG GTGACAACCT GAGCATAGGG CAGAGGCAGC TCCTATGCCT GGGTAGGGCC 
GTGCTTCGAA AATCCAAAAT CCTGGTCCTG GACGAAGCCA CAGCCGCAGT GGATCTAGAG 
ACGGATAGCC TCATTCAGAC GACCATCCGG AACGAGTTCT CCCAGTGCAC GGTCATCACT 
ATCGCACACA GGCTGCACAC CATCATGGAC AGTGACAAGA TAATGGTCCT AGACAGCGGC 
AAGATTGTTG AATACGGCAG TCCTGAAGAA CTGCTGTCCA ATATGGGTCC CTTCTACTTG 
ATGGCCAAGG AAGCCGGCAT TGAAAGTGTG AACCACACGG AGCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006526688.1
CDS	171..4658
Translation	MAVAALSQSKRYRKTKELKPVFVVCLLILAAIDLSLALTEDTGQATIPPVKYTNPILYLCTWLLVLVIQHCRQCCIQKNSWFLSMFWILSLLCGIFQFQTLIRALLQDSKSNMTYSCLFFVSYGFQIVILILSAFSESSDSTHAPSATASFLSSVTFSWYDSTVLKGYKHPLTIEDVWDIEENLKAKSLTSKFKTIMTKDLQKARQALQRRLKKSQQSPEGTSHGLTKKQSQSQDVLVLEDSKKKKKKSEATKDFPKSWLVKALFKTFYVVILKSFILKLAHDILLFLNPQLLKFLIGFVKDPDSYPWVGYIYAILMFSVTLIQSFFLQCYFQFCFVLGMTVRTTIIASVYKKALTLSNLARRQYTIGETVNLMSVDSQKLMDVTNYIHLLWSSVLQIALSIFFLWRELGPSILAGVGLMVLLVPVNGVLATKIRKIQVQNMKNKDKRLKIMNEILSGIKILKYFAWEPSFKEQVNSIRKKELRNLLRFSQLQTILIFILHLTPTLVSVITFSVYVLVDSQNVLNAEKAFTSITLFNILRFPLAMLPMVISSVIQASVSVDRLEQYLGSDDLDLSAIRHVCHFDKAVQFSEASFTWDRDLEATIQDVNLDIKPGQLVAVVGTVGSGKSSLISAMLGEMENVHGHITIKGSIAYVPQQAWIQNGTIKDNILFGSEYDEKKYQRVIEACALLPDLEMLPGGDMAEIGEKGINLSGGQKHRVSLARATYQDADIYILDDPLSAVDTHVGKHIFNKVVGPNGLLSGKTRILVTHGIHFLPQVDEIVVLGKGTILEKGSYSDLMDKKGVFAKNWKTFMKHSGPEGEATVDNDSEEEDGDCGLIPTVEEIPDDAASLTMRRENSLRRTLSRSSRSGSRRGKSLKSSLKIKSVNALNKKEEVVKGQKLIKKEFVETGKVKFSIYLKYLQAVGWWSLLFIVIFYVLNYVAFIGTNLWLSAWTSDSEKQNGTDNSPSQRDMRIGVFGALGIAQGIFLLSSSLWSIYACRNASKTLHRQLLTNILRAPMSFFDTTPTGRIVNRFAGDISTVDDTLPQTLRSWLLCFFGIVSTLVMICMATPIFIIIIIPLSILYVSVQVFYVATSRQLRRLDSVTKSPIYSHFSETVSGLPVIRAFEHQQRFLANSEKQIDTNQKCVFSWITSNRWLAIRLELVGNLIVFCSALLLVIYKNSLTGDTVGFVLSNALNITQTLNWLVRMTSEVETNIVAVERINEYINVDNEAPWVTDKKPPADWPKKGEIQFNNYQVRYRPELDLVLKGITCNIKSTEKVGVVGRTGAGKSSLTNCLFRILESAGGQIIIDGIDIASIGLHDLRGRLTIIPQDPILFSGNLRMNLDPFNKYSDEEIWRALELAHLKSFVAGLQLGLLHEVTEGGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRNEFSQCTVITIAHRLHTIMDSDKIMVLDSGKIVEYGSPEELLSNMGPFYLMAKEAGIESVNHTEL

Target ORF information:

RefSeq Version	XM_006526625.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (Abcc2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006526625.4

ORF Insert Sequence:

ATGGCTGTGG CAGCGCTGAG TCAGAGCAAG AGGTACAGAA AAACAAAGGA GCTCAAACCA 
GTGTTCGTTG TGTGTCTTCT TATTTTAGCA GCCATAGACC TGTCTCTTGC ACTCACAGAA 
GATACTGGAC AAGCCACAAT TCCTCCTGTT AAATATACAA ATCCAATTCT CTACCTATGC 
ACTTGGCTCC TGGTGTTGGT GATCCAACAC TGCAGGCAAT GCTGTATACA GAAGAATTCT 
TGGTTCCTGT CCATGTTCTG GATTCTCTCT CTATTATGTG GCATATTCCA GTTTCAGACT 
CTGATACGAG CACTCCTGCA GGATAGCAAG TCCAACATGA CCTATTCCTG CCTGTTCTTC 
GTCTCCTATG GTTTCCAGAT TGTCATTTTG ATCCTTTCAG CCTTTTCAGA ATCAAGCGAC 
TCAACACACG CCCCATCAGC TACAGCTTCA TTTCTGAGTA GCGTTACGTT TAGTTGGTAT 
GACAGCACTG TTCTGAAAGG TTACAAGCAT CCATTGACAA TAGAAGATGT GTGGGATATT 
GAAGAAAATC TTAAAGCCAA GTCACTCACC AGCAAGTTTA AGACGATCAT GACAAAGGAC 
CTGCAGAAAG CCAGGCAGGC TCTTCAGAGG CGGCTGAAGA AGTCCCAGCA GAGCCCTGAG 
GGCACGTCAC ACGGATTGAC CAAGAAGCAG AGTCAGAGCC AAGATGTCCT TGTCCTGGAA 
GACTCGAAAA AGAAGAAAAA GAAGTCTGAG GCCACCAAAG ACTTTCCCAA ATCCTGGTTG 
GTGAAGGCTC TCTTCAAAAC GTTCTACGTG GTGATCCTGA AGTCATTTAT TCTGAAATTA 
GCACATGATA TTCTTTTGTT TCTGAATCCT CAGCTGCTGA AATTTCTCAT TGGCTTCGTG 
AAAGACCCTG ACTCATATCC GTGGGTTGGA TATATCTATG CAATCCTAAT GTTCTCTGTG 
ACTCTCATCC AGTCTTTCTT CCTTCAGTGT TATTTTCAAT TTTGTTTTGT GTTGGGAATG 
ACTGTACGGA CAACCATCAT AGCTTCCGTA TATAAGAAGG CACTAACCCT ATCTAACTTG 
GCTAGGAGGC AGTACACGAT TGGAGAGACG GTGAACTTGA TGTCTGTAGA TTCCCAGAAG 
CTAATGGACG TGACCAACTA CATACACTTG CTGTGGTCCA GTGTTTTACA GATTGCTTTG 
TCCATTTTCT TCCTGTGGAG AGAGTTGGGA CCTTCGATTT TAGCAGGTGT TGGGCTTATG 
GTTCTCCTGG TCCCAGTTAA TGGCGTCCTG GCTACCAAGA TCAGGAAAAT TCAGGTCCAG 
AATATGAAGA ATAAAGACAA ACGCTTAAAA ATCATGAATG AGATTCTTAG TGGGATTAAG 
ATCCTGAAAT ACTTTGCCTG GGAACCTTCC TTTAAAGAGC AAGTGAACAG CATTCGGAAG 
AAAGAACTCA GGAACTTGCT GCGCTTCAGC CAGCTGCAGA CGATTTTGAT TTTCATCTTA 
CACCTAACTC CAACCCTGGT GTCCGTGATC ACATTTTCTG TTTACGTCCT GGTGGATAGT 
CAAAATGTTT TGAACGCGGA GAAGGCTTTC ACCTCCATCA CCCTCTTCAA TATCCTGCGC 
TTTCCTCTGG CCATGCTTCC CATGGTGATC TCTTCAGTCA TCCAGGCCAG CGTCTCTGTA 
GACCGGCTGG AGCAGTACCT GGGAAGCGAT GATCTGGACT TGTCTGCCAT TCGCCATGTC 
TGCCATTTTG ATAAAGCTGT GCAGTTCTCA GAAGCCTCTT TTACTTGGGA CCGGGACTTG 
GAAGCCACAA TCCAAGATGT GAACCTGGAC ATAAAACCAG GCCAACTGGT GGCTGTGGTG 
GGCACTGTAG GCTCTGGGAA GTCCTCTTTG ATATCAGCCA TGCTGGGAGA AATGGAGAAT 
GTCCATGGGC ATATCACCAT CAAGGGCTCC ATAGCCTACG TCCCTCAGCA GGCCTGGATT 
CAGAACGGGA CCATCAAAGA TAACATCCTG TTTGGGTCAG AATACGATGA AAAGAAGTAC 
CAGCGAGTTA TCGAAGCGTG CGCTCTCCTC CCAGACTTGG AAATGTTGCC TGGAGGAGAC 
ATGGCTGAGA TCGGAGAGAA GGGTATAAAT CTCAGTGGCG GTCAGAAGCA TCGAGTCAGC 
CTGGCCCGGG CCACCTATCA AGATGCAGAC ATCTATATTC TAGACGACCC CCTGTCGGCT 
GTGGACACTC ACGTGGGAAA ACACATTTTC AACAAGGTTG TGGGCCCCAA TGGCCTGCTG 
AGCGGCAAGA CTCGGATCTT GGTTACACAT GGCATTCACT TCCTTCCCCA AGTGGATGAG 
ATTGTCGTTC TGGGGAAAGG CACCATCTTA GAGAAGGGAT CCTATAGTGA CCTGATGGAC 
AAGAAAGGAG TGTTCGCTAA GAACTGGAAG ACATTCATGA AGCATTCGGG ACCTGAAGGA 
GAGGCTACAG TCGATAACGA CAGTGAGGAA GAGGATGGTG ACTGTGGGCT GATCCCAACT 
GTGGAGGAAA TTCCTGACGA TGCAGCTTCC TTGACCATGA GAAGGGAGAA CAGCCTTCGC 
CGAACACTGA GCCGCAGCTC TAGGTCCGGC AGCAGGCGTG GGAAGTCCCT CAAAAGCTCC 
TTGAAAATTA AAAGTGTGAA TGCCTTGAAT AAGAAGGAGG AAGTAGTGAA AGGACAAAAA 
CTAATTAAGA AGGAATTTGT GGAAACTGGG AAGGTAAAGT TCTCCATCTA CCTGAAATAT 
CTGCAGGCGG TAGGATGGTG GTCCCTGCTC TTCATCGTCA TCTTCTACGT ATTGAACTAT 
GTGGCTTTTA TTGGCACTAA CCTCTGGCTG AGTGCTTGGA CCAGTGACTC TGAAAAACAG 
AATGGGACCG ACAATTCACC TTCTCAGAGG GACATGAGAA TCGGGGTCTT TGGAGCTCTG 
GGAATAGCAC AAGGTATATT TTTGCTTAGT TCAAGTCTAT GGAGTATATA TGCTTGCAGA 
AATGCATCCA AAACTTTGCA CAGGCAGCTG TTAACCAACA TTCTCCGCGC ACCCATGAGT 
TTTTTTGACA CAACTCCCAC AGGCCGGATT GTGAACAGAT TTGCCGGGGA TATTTCTACG 
GTGGACGACA CACTCCCCCA GACTTTGCGA AGCTGGCTGC TGTGTTTCTT CGGCATAGTT 
AGCACTCTCG TGATGATCTG CATGGCCACC CCCATCTTCA TCATCATCAT CATCCCTCTC 
AGCATTCTCT ATGTATCTGT GCAGGTGTTT TATGTGGCTA CATCCCGCCA GCTGAGACGG 
CTGGATTCTG TCACCAAATC TCCGATCTAT TCTCACTTTA GTGAGACTGT CTCTGGTTTG 
CCTGTTATTC GGGCCTTTGA GCACCAGCAG AGATTTCTAG CAAACAGTGA GAAGCAGATT 
GACACCAACC AGAAATGCGT CTTTTCCTGG ATTACCTCCA ACCGGTGGCT TGCCATTCGC 
CTGGAGCTGG TTGGAAACCT GATTGTCTTC TGCTCGGCCT TGCTTCTGGT TATTTATAAG 
AATTCCTTAA CCGGGGACAC TGTGGGCTTT GTTCTGTCCA ACGCCCTCAA CATCACACAA 
ACCCTGAACT GGCTAGTGAG GATGACGTCA GAAGTAGAGA CCAACATCGT GGCTGTTGAG 
CGAATAAATG AATACATAAA TGTGGATAAT GAGGCGCCGT GGGTGACCGA CAAGAAGCCT 
CCGGCAGATT GGCCCAAAAA AGGTGAGATC CAGTTCAACA ACTATCAAGT GCGGTATCGG 
CCGGAGCTGG ATCTGGTCCT GAAAGGGATT ACTTGTAACA TCAAGAGCAC CGAGAAGGTC 
GGTGTGGTGG GCAGGACCGG AGCTGGAAAA TCATCCCTCA CAAACTGCCT CTTCAGAATC 
TTAGAGTCTG CAGGTGGCCA GATCATCATT GATGGGATTG ATATTGCCTC CATTGGACTG 
CACGACCTTC GAGGGAGACT GACCATCATT CCCCAGGACC CCATTTTGTT CTCTGGGAAT 
CTGAGGATGA ATCTCGACCC TTTCAACAAA TACTCGGATG AGGAGATCTG GAGGGCCCTG 
GAATTGGCTC ATCTCAAATC CTTTGTGGCT GGCCTGCAAC TTGGGTTGCT CCATGAAGTG 
ACAGAGGGCG GTGACAACCT GAGCATAGGG CAGAGGCAGC TCCTATGCCT GGGTAGGGCC 
GTGCTTCGAA AATCCAAAAT CCTGGTCCTG GACGAAGCCA CAGCCGCAGT GGATCTAGAG 
ACGGATAGCC TCATTCAGAC GACCATCCGG AACGAGTTCT CCCAGTGCAC GGTCATCACT 
ATCGCACACA GGCTGCACAC CATCATGGAC AGTGACAAGA TAATGGTCCT AGACAGCGGC 
AAGATTGTTG AATACGGCAG TCCTGAAGAA CTGCTGTCCA ATATGGGTCC CTTCTACTTG 
ATGGCCAAGG AAGCCGGCAT TGAAAGTGTG AACCACACGG AGCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abcc2 ( NM_013806.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_038834.2 Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (Abcc2), mRNA.

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CloneID	OMu21658
Clone ID Related Accession (Same CDS sequence)	NM_013806.2
Accession Version	NM_013806.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4632bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	canalicular multispecific organic anion transporter 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC141888.4, AF282773.1 and AC132251.3. On Oct 12, 2006 this sequence version replaced NM_013806.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF282772.1, AF282773.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849385 [ECO:0000348] ##Evidence-Data-END##

ATGGACGAAT TCTGCAACTC TACTTTTTGG AATCTCTCAT TATTGAAAAG TCCGGAAGCC 
GACCTGCCTC TTTGTTTTGA ACAAACTGTT CTTGTGTGGA TTCCCTTGGG CTTTCTTTGG 
CTCTTGGCGC CTTGGCAACT TTACAGAATA TACAGATCCA GGACCAAGAG ATTTGCTATA 
ACTAAATTCT ACCTTGCCAA GCAGGTGTTC GTTGTGTGTC TTCTTATTTT AGCAGCCATA 
GACCTGTCTC TTGCACTCAC AGAAGATACT GGACAAGCCA CAATTCCTCC TGTTAAATAT 
ACAAATCCAA TTCTCTACCT ATGCACTTGG CTCCTGGTGT TGGTGATCCA ACACTGCAGG 
CAATGCTGTA TACAGAAGAA TTCTTGGTTC CTGTCCATGT TCTGGATTCT CTCTCTATTA 
TGTGGCATAT TCCAGTTTCA GACTCTGATA CGAGCACTCC TGCAGGATAG CAAGTCCAAC 
ATGACCTATT CCTGCCTGTT CTTCGTCTCC TATGGTTTCC AGATTGTCAT TTTGATCCTT 
TCAGCCTTTT CAGAATCAAG CGACTCAACA CACGCCCCAT CAGCTACAGC TTCATTTCTG 
AGTAGCGTTA CGTTTAGTTG GTATGACAGC ACTGTTCTGA AAGGTTACAA GCATCCATTG 
ACAATAGAAG ATGTGTGGGA TATTGAAGAA AATCTTAAAG CCAAGTCACT CACCAGCAAG 
TTTAAGACGA TCATGACAAA GGACCTGCAG AAAGCCAGGC AGGCTCTTCA GAGGCGGCTG 
AAGAAGTCCC AGCAGAGCCC TGAGGGCACG TCACACGGAT TGACCAAGAA GCAGAGTCAG 
AGCCAAGATG TCCTTGTCCT GGAAGACTCG AAAAAGAAGA AAAAGAAGTC TGAGGCCACC 
AAAGACTTTC CCAAATCCTG GTTGGTGAAG GCTCTCTTCA AAACGTTCTA CGTGGTGATC 
CTGAAGTCAT TTATTCTGAA ATTAGCACAT GATATTCTTT TGTTTCTGAA TCCTCAGCTG 
CTGAAATTTC TCATTGGCTT CGTGAAAGAC CCTGACTCAT ATCCGTGGGT TGGATATATC 
TATGCAATCC TAATGTTCTC TGTGACTCTC ATCCAGTCTT TCTTCCTTCA GTGTTATTTT 
CAATTTTGTT TTGTGTTGGG AATGACTGTA CGGACAACCA TCATAGCTTC CGTATATAAG 
AAGGCACTAA CCCTATCTAA CTTGGCTAGG AGGCAGTACA CGATTGGAGA GACGGTGAAC 
TTGATGTCTG TAGATTCCCA GAAGCTAATG GACGTGACCA ACTACATACA CTTGCTGTGG 
TCCAGTGTTT TACAGATTGC TTTGTCCATT TTCTTCCTGT GGAGAGAGTT GGGACCTTCG 
ATTTTAGCAG GTGTTGGGCT TATGGTTCTC CTGGTCCCAG TTAATGGCGT CCTGGCTACC 
AAGATCAGGA AAATTCAGGT CCAGAATATG AAGAATAAAG ACAAACGCTT AAAAATCATG 
AATGAGATTC TTAGTGGGAT TAAGATCCTG AAATACTTTG CCTGGGAACC TTCCTTTAAA 
GAGCAAGTGA ACAGCATTCG GAAGAAAGAA CTCAGGAACT TGCTGCGCTT CAGCCAGCTG 
CAGACGATTT TGATTTTCAT CTTACACCTA ACTCCAACCC TGGTGTCCGT GATCACATTT 
TCTGTTTACG TCCTGGTGGA TAGTCAAAAT GTTTTGAACG CGGAGAAGGC TTTCACCTCC 
ATCACCCTCT TCAATATCCT GCGCTTTCCT CTGGCCATGC TTCCCATGGT GATCTCTTCA 
GTCATCCAGG CCAGCGTCTC TGTAGACCGG CTGGAGCAGT ACCTGGGAAG CGATGATCTG 
GACTTGTCTG CCATTCGCCA TGTCTGCCAT TTTGATAAAG CTGTGCAGTT CTCAGAAGCC 
TCTTTTACTT GGGACCGGGA CTTGGAAGCC ACAATCCAAG ATGTGAACCT GGACATAAAA 
CCAGGCCAAC TGGTGGCTGT GGTGGGCACT GTAGGCTCTG GGAAGTCCTC TTTGATATCA 
GCCATGCTGG GAGAAATGGA GAATGTCCAT GGGCATATCA CCATCAAGGG CTCCATAGCC 
TACGTCCCTC AGCAGGCCTG GATTCAGAAC GGGACCATCA AAGATAACAT CCTGTTTGGG 
TCAGAATACG ATGAAAAGAA GTACCAGCGA GTTATCGAAG CGTGCGCTCT CCTCCCAGAC 
TTGGAAATGT TGCCTGGAGG AGACATGGCT GAGATCGGAG AGAAGGGTAT AAATCTCAGT 
GGCGGTCAGA AGCATCGAGT CAGCCTGGCC CGGGCCACCT ATCAAGATGC AGACATCTAT 
ATTCTAGACG ACCCCCTGTC GGCTGTGGAC ACTCACGTGG GAAAACACAT TTTCAACAAG 
GTTGTGGGCC CCAATGGCCT GCTGAGCGGC AAGACTCGGA TCTTGGTTAC ACATGGCATT 
CACTTCCTTC CCCAAGTGGA TGAGATTGTC GTTCTGGGGA AAGGCACCAT CTTAGAGAAG 
GGATCCTATA GTGACCTGAT GGACAAGAAA GGAGTGTTCG CTAAGAACTG GAAGACATTC 
ATGAAGCATT CGGGACCTGA AGGAGAGGCT ACAGTCGATA ACGACAGTGA GGAAGAGGAT 
GGTGACTGTG GGCTGATCCC AACTGTGGAG GAAATTCCTG ACGATGCAGC TTCCTTGACC 
ATGAGAAGGG AGAACAGCCT TCGCCGAACA CTGAGCCGCA GCTCTAGGTC CGGCAGCAGG 
CGTGGGAAGT CCCTCAAAAG CTCCTTGAAA ATTAAAAGTG TGAATGCCTT GAATAAGAAG 
GAGGAAGTAG TGAAAGGACA AAAACTAATT AAGAAGGAAT TTGTGGAAAC TGGGAAGGTA 
AAGTTCTCCA TCTACCTGAA ATATCTGCAG GCGGTAGGAT GGTGGTCCCT GCTCTTCATC 
GTCATCTTCT ACGTATTGAA CTATGTGGCT TTTATTGGCA CTAACCTCTG GCTGAGTGCT 
TGGACCAGTG ACTCTGAAAA ACAGAATGGG ACCGACAATT CACCTTCTCA GAGGGACATG 
AGAATCGGGG TCTTTGGAGC TCTGGGAATA GCACAAGGTA TATTTTTGCT TAGTTCAAGT 
CTATGGAGTA TATATGCTTG CAGAAATGCA TCCAAAACTT TGCACAGGCA GCTGTTAACC 
AACATTCTCC GCGCACCCAT GAGTTTTTTT GACACAACTC CCACAGGCCG GATTGTGAAC 
AGATTTGCCG GGGATATTTC TACGGTGGAC GACACACTCC CCCAGACTTT GCGAAGCTGG 
CTGCTGTGTT TCTTCGGCAT AGTTAGCACT CTCGTGATGA TCTGCATGGC CACCCCCATC 
TTCATCATCA TCATCATCCC TCTCAGCATT CTCTATGTAT CTGTGCAGGT GTTTTATGTG 
GCTACATCCC GCCAGCTGAG ACGGCTGGAT TCTGTCACCA AATCTCCGAT CTATTCTCAC 
TTTAGTGAGA CTGTCTCTGG TTTGCCTGTT ATTCGGGCCT TTGAGCACCA GCAGAGATTT 
CTAGCAAACA GTGAGAAGCA GATTGACACC AACCAGAAAT GCGTCTTTTC CTGGATTACC 
TCCAACCGGT GGCTTGCCAT TCGCCTGGAG CTGGTTGGAA ACCTGATTGT CTTCTGCTCG 
GCCTTGCTTC TGGTTATTTA TAAGAATTCC TTAACCGGGG ACACTGTGGG CTTTGTTCTG 
TCCAACGCCC TCAACATCAC ACAAACCCTG AACTGGCTAG TGAGGATGAC GTCAGAAGTA 
GAGACCAACA TCGTGGCTGT TGAGCGAATA AATGAATACA TAAATGTGGA TAATGAGGCG 
CCGTGGGTGA CCGACAAGAA GCCTCCGGCA GATTGGCCCA AAAAAGGTGA GATCCAGTTC 
AACAACTATC AAGTGCGGTA TCGGCCGGAG CTGGATCTGG TCCTGAAAGG GATTACTTGT 
AACATCAAGA GCACCGAGAA GGTCGGTGTG GTGGGCAGGA CCGGAGCTGG AAAATCATCC 
CTCACAAACT GCCTCTTCAG AATCTTAGAG TCTGCAGGTG GCCAGATCAT CATTGATGGG 
ATTGATATTG CCTCCATTGG ACTGCACGAC CTTCGAGGGA GACTGACCAT CATTCCCCAG 
GACCCCATTT TGTTCTCTGG GAATCTGAGG ATGAATCTCG ACCCTTTCAA CAAATACTCG 
GATGAGGAGA TCTGGAGGGC CCTGGAATTG GCTCATCTCA AATCCTTTGT GGCTGGCCTG 
CAACTTGGGT TGCTCCATGA AGTGACAGAG GGCGGTGACA ACCTGAGCAT AGGGCAGAGG 
CAGCTCCTAT GCCTGGGTAG GGCCGTGCTT CGAAAATCCA AAATCCTGGT CCTGGACGAA 
GCCACAGCCG CAGTGGATCT AGAGACGGAT AGCCTCATTC AGACGACCAT CCGGAACGAG 
TTCTCCCAGT GCACGGTCAT CACTATCGCA CACAGGCTGC ACACCATCAT GGACAGTGAC 
AAGATAATGG TCCTAGACAG CGGCAAGATT GTTGAATACG GCAGTCCTGA AGAACTGCTG 
TCCAATATGG GTCCCTTCTA CTTGATGGCC AAGGAAGCCG GCATTGAAAG TGTGAACCAC 
ACGGAGCTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038834.2
CDS	97..4728
Translation	MDEFCNSTFWNLSLLKSPEADLPLCFEQTVLVWIPLGFLWLLAPWQLYRIYRSRTKRFAITKFYLAKQVFVVCLLILAAIDLSLALTEDTGQATIPPVKYTNPILYLCTWLLVLVIQHCRQCCIQKNSWFLSMFWILSLLCGIFQFQTLIRALLQDSKSNMTYSCLFFVSYGFQIVILILSAFSESSDSTHAPSATASFLSSVTFSWYDSTVLKGYKHPLTIEDVWDIEENLKAKSLTSKFKTIMTKDLQKARQALQRRLKKSQQSPEGTSHGLTKKQSQSQDVLVLEDSKKKKKKSEATKDFPKSWLVKALFKTFYVVILKSFILKLAHDILLFLNPQLLKFLIGFVKDPDSYPWVGYIYAILMFSVTLIQSFFLQCYFQFCFVLGMTVRTTIIASVYKKALTLSNLARRQYTIGETVNLMSVDSQKLMDVTNYIHLLWSSVLQIALSIFFLWRELGPSILAGVGLMVLLVPVNGVLATKIRKIQVQNMKNKDKRLKIMNEILSGIKILKYFAWEPSFKEQVNSIRKKELRNLLRFSQLQTILIFILHLTPTLVSVITFSVYVLVDSQNVLNAEKAFTSITLFNILRFPLAMLPMVISSVIQASVSVDRLEQYLGSDDLDLSAIRHVCHFDKAVQFSEASFTWDRDLEATIQDVNLDIKPGQLVAVVGTVGSGKSSLISAMLGEMENVHGHITIKGSIAYVPQQAWIQNGTIKDNILFGSEYDEKKYQRVIEACALLPDLEMLPGGDMAEIGEKGINLSGGQKHRVSLARATYQDADIYILDDPLSAVDTHVGKHIFNKVVGPNGLLSGKTRILVTHGIHFLPQVDEIVVLGKGTILEKGSYSDLMDKKGVFAKNWKTFMKHSGPEGEATVDNDSEEEDGDCGLIPTVEEIPDDAASLTMRRENSLRRTLSRSSRSGSRRGKSLKSSLKIKSVNALNKKEEVVKGQKLIKKEFVETGKVKFSIYLKYLQAVGWWSLLFIVIFYVLNYVAFIGTNLWLSAWTSDSEKQNGTDNSPSQRDMRIGVFGALGIAQGIFLLSSSLWSIYACRNASKTLHRQLLTNILRAPMSFFDTTPTGRIVNRFAGDISTVDDTLPQTLRSWLLCFFGIVSTLVMICMATPIFIIIIIPLSILYVSVQVFYVATSRQLRRLDSVTKSPIYSHFSETVSGLPVIRAFEHQQRFLANSEKQIDTNQKCVFSWITSNRWLAIRLELVGNLIVFCSALLLVIYKNSLTGDTVGFVLSNALNITQTLNWLVRMTSEVETNIVAVERINEYINVDNEAPWVTDKKPPADWPKKGEIQFNNYQVRYRPELDLVLKGITCNIKSTEKVGVVGRTGAGKSSLTNCLFRILESAGGQIIIDGIDIASIGLHDLRGRLTIIPQDPILFSGNLRMNLDPFNKYSDEEIWRALELAHLKSFVAGLQLGLLHEVTEGGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRNEFSQCTVITIAHRLHTIMDSDKIMVLDSGKIVEYGSPEELLSNMGPFYLMAKEAGIESVNHTEL

Target ORF information:

RefSeq Version	NM_013806.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (Abcc2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013806.2

ORF Insert Sequence:

ATGGACGAAT TCTGCAACTC TACTTTTTGG AATCTCTCAT TATTGAAAAG TCCGGAAGCC 
GACCTGCCTC TTTGTTTTGA ACAAACTGTT CTTGTGTGGA TTCCCTTGGG CTTTCTTTGG 
CTCTTGGCGC CTTGGCAACT TTACAGAATA TACAGATCCA GGACCAAGAG ATTTGCTATA 
ACTAAATTCT ACCTTGCCAA GCAGGTGTTC GTTGTGTGTC TTCTTATTTT AGCAGCCATA 
GACCTGTCTC TTGCACTCAC AGAAGATACT GGACAAGCCA CAATTCCTCC TGTTAAATAT 
ACAAATCCAA TTCTCTACCT ATGCACTTGG CTCCTGGTGT TGGTGATCCA ACACTGCAGG 
CAATGCTGTA TACAGAAGAA TTCTTGGTTC CTGTCCATGT TCTGGATTCT CTCTCTATTA 
TGTGGCATAT TCCAGTTTCA GACTCTGATA CGAGCACTCC TGCAGGATAG CAAGTCCAAC 
ATGACCTATT CCTGCCTGTT CTTCGTCTCC TATGGTTTCC AGATTGTCAT TTTGATCCTT 
TCAGCCTTTT CAGAATCAAG CGACTCAACA CACGCCCCAT CAGCTACAGC TTCATTTCTG 
AGTAGCGTTA CGTTTAGTTG GTATGACAGC ACTGTTCTGA AAGGTTACAA GCATCCATTG 
ACAATAGAAG ATGTGTGGGA TATTGAAGAA AATCTTAAAG CCAAGTCACT CACCAGCAAG 
TTTAAGACGA TCATGACAAA GGACCTGCAG AAAGCCAGGC AGGCTCTTCA GAGGCGGCTG 
AAGAAGTCCC AGCAGAGCCC TGAGGGCACG TCACACGGAT TGACCAAGAA GCAGAGTCAG 
AGCCAAGATG TCCTTGTCCT GGAAGACTCG AAAAAGAAGA AAAAGAAGTC TGAGGCCACC 
AAAGACTTTC CCAAATCCTG GTTGGTGAAG GCTCTCTTCA AAACGTTCTA CGTGGTGATC 
CTGAAGTCAT TTATTCTGAA ATTAGCACAT GATATTCTTT TGTTTCTGAA TCCTCAGCTG 
CTGAAATTTC TCATTGGCTT CGTGAAAGAC CCTGACTCAT ATCCGTGGGT TGGATATATC 
TATGCAATCC TAATGTTCTC TGTGACTCTC ATCCAGTCTT TCTTCCTTCA GTGTTATTTT 
CAATTTTGTT TTGTGTTGGG AATGACTGTA CGGACAACCA TCATAGCTTC CGTATATAAG 
AAGGCACTAA CCCTATCTAA CTTGGCTAGG AGGCAGTACA CGATTGGAGA GACGGTGAAC 
TTGATGTCTG TAGATTCCCA GAAGCTAATG GACGTGACCA ACTACATACA CTTGCTGTGG 
TCCAGTGTTT TACAGATTGC TTTGTCCATT TTCTTCCTGT GGAGAGAGTT GGGACCTTCG 
ATTTTAGCAG GTGTTGGGCT TATGGTTCTC CTGGTCCCAG TTAATGGCGT CCTGGCTACC 
AAGATCAGGA AAATTCAGGT CCAGAATATG AAGAATAAAG ACAAACGCTT AAAAATCATG 
AATGAGATTC TTAGTGGGAT TAAGATCCTG AAATACTTTG CCTGGGAACC TTCCTTTAAA 
GAGCAAGTGA ACAGCATTCG GAAGAAAGAA CTCAGGAACT TGCTGCGCTT CAGCCAGCTG 
CAGACGATTT TGATTTTCAT CTTACACCTA ACTCCAACCC TGGTGTCCGT GATCACATTT 
TCTGTTTACG TCCTGGTGGA TAGTCAAAAT GTTTTGAACG CGGAGAAGGC TTTCACCTCC 
ATCACCCTCT TCAATATCCT GCGCTTTCCT CTGGCCATGC TTCCCATGGT GATCTCTTCA 
GTCATCCAGG CCAGCGTCTC TGTAGACCGG CTGGAGCAGT ACCTGGGAAG CGATGATCTG 
GACTTGTCTG CCATTCGCCA TGTCTGCCAT TTTGATAAAG CTGTGCAGTT CTCAGAAGCC 
TCTTTTACTT GGGACCGGGA CTTGGAAGCC ACAATCCAAG ATGTGAACCT GGACATAAAA 
CCAGGCCAAC TGGTGGCTGT GGTGGGCACT GTAGGCTCTG GGAAGTCCTC TTTGATATCA 
GCCATGCTGG GAGAAATGGA GAATGTCCAT GGGCATATCA CCATCAAGGG CTCCATAGCC 
TACGTCCCTC AGCAGGCCTG GATTCAGAAC GGGACCATCA AAGATAACAT CCTGTTTGGG 
TCAGAATACG ATGAAAAGAA GTACCAGCGA GTTATCGAAG CGTGCGCTCT CCTCCCAGAC 
TTGGAAATGT TGCCTGGAGG AGACATGGCT GAGATCGGAG AGAAGGGTAT AAATCTCAGT 
GGCGGTCAGA AGCATCGAGT CAGCCTGGCC CGGGCCACCT ATCAAGATGC AGACATCTAT 
ATTCTAGACG ACCCCCTGTC GGCTGTGGAC ACTCACGTGG GAAAACACAT TTTCAACAAG 
GTTGTGGGCC CCAATGGCCT GCTGAGCGGC AAGACTCGGA TCTTGGTTAC ACATGGCATT 
CACTTCCTTC CCCAAGTGGA TGAGATTGTC GTTCTGGGGA AAGGCACCAT CTTAGAGAAG 
GGATCCTATA GTGACCTGAT GGACAAGAAA GGAGTGTTCG CTAAGAACTG GAAGACATTC 
ATGAAGCATT CGGGACCTGA AGGAGAGGCT ACAGTCGATA ACGACAGTGA GGAAGAGGAT 
GGTGACTGTG GGCTGATCCC AACTGTGGAG GAAATTCCTG ACGATGCAGC TTCCTTGACC 
ATGAGAAGGG AGAACAGCCT TCGCCGAACA CTGAGCCGCA GCTCTAGGTC CGGCAGCAGG 
CGTGGGAAGT CCCTCAAAAG CTCCTTGAAA ATTAAAAGTG TGAATGCCTT GAATAAGAAG 
GAGGAAGTAG TGAAAGGACA AAAACTAATT AAGAAGGAAT TTGTGGAAAC TGGGAAGGTA 
AAGTTCTCCA TCTACCTGAA ATATCTGCAG GCGGTAGGAT GGTGGTCCCT GCTCTTCATC 
GTCATCTTCT ACGTATTGAA CTATGTGGCT TTTATTGGCA CTAACCTCTG GCTGAGTGCT 
TGGACCAGTG ACTCTGAAAA ACAGAATGGG ACCGACAATT CACCTTCTCA GAGGGACATG 
AGAATCGGGG TCTTTGGAGC TCTGGGAATA GCACAAGGTA TATTTTTGCT TAGTTCAAGT 
CTATGGAGTA TATATGCTTG CAGAAATGCA TCCAAAACTT TGCACAGGCA GCTGTTAACC 
AACATTCTCC GCGCACCCAT GAGTTTTTTT GACACAACTC CCACAGGCCG GATTGTGAAC 
AGATTTGCCG GGGATATTTC TACGGTGGAC GACACACTCC CCCAGACTTT GCGAAGCTGG 
CTGCTGTGTT TCTTCGGCAT AGTTAGCACT CTCGTGATGA TCTGCATGGC CACCCCCATC 
TTCATCATCA TCATCATCCC TCTCAGCATT CTCTATGTAT CTGTGCAGGT GTTTTATGTG 
GCTACATCCC GCCAGCTGAG ACGGCTGGAT TCTGTCACCA AATCTCCGAT CTATTCTCAC 
TTTAGTGAGA CTGTCTCTGG TTTGCCTGTT ATTCGGGCCT TTGAGCACCA GCAGAGATTT 
CTAGCAAACA GTGAGAAGCA GATTGACACC AACCAGAAAT GCGTCTTTTC CTGGATTACC 
TCCAACCGGT GGCTTGCCAT TCGCCTGGAG CTGGTTGGAA ACCTGATTGT CTTCTGCTCG 
GCCTTGCTTC TGGTTATTTA TAAGAATTCC TTAACCGGGG ACACTGTGGG CTTTGTTCTG 
TCCAACGCCC TCAACATCAC ACAAACCCTG AACTGGCTAG TGAGGATGAC GTCAGAAGTA 
GAGACCAACA TCGTGGCTGT TGAGCGAATA AATGAATACA TAAATGTGGA TAATGAGGCG 
CCGTGGGTGA CCGACAAGAA GCCTCCGGCA GATTGGCCCA AAAAAGGTGA GATCCAGTTC 
AACAACTATC AAGTGCGGTA TCGGCCGGAG CTGGATCTGG TCCTGAAAGG GATTACTTGT 
AACATCAAGA GCACCGAGAA GGTCGGTGTG GTGGGCAGGA CCGGAGCTGG AAAATCATCC 
CTCACAAACT GCCTCTTCAG AATCTTAGAG TCTGCAGGTG GCCAGATCAT CATTGATGGG 
ATTGATATTG CCTCCATTGG ACTGCACGAC CTTCGAGGGA GACTGACCAT CATTCCCCAG 
GACCCCATTT TGTTCTCTGG GAATCTGAGG ATGAATCTCG ACCCTTTCAA CAAATACTCG 
GATGAGGAGA TCTGGAGGGC CCTGGAATTG GCTCATCTCA AATCCTTTGT GGCTGGCCTG 
CAACTTGGGT TGCTCCATGA AGTGACAGAG GGCGGTGACA ACCTGAGCAT AGGGCAGAGG 
CAGCTCCTAT GCCTGGGTAG GGCCGTGCTT CGAAAATCCA AAATCCTGGT CCTGGACGAA 
GCCACAGCCG CAGTGGATCT AGAGACGGAT AGCCTCATTC AGACGACCAT CCGGAACGAG 
TTCTCCCAGT GCACGGTCAT CACTATCGCA CACAGGCTGC ACACCATCAT GGACAGTGAC 
AAGATAATGG TCCTAGACAG CGGCAAGATT GTTGAATACG GCAGTCCTGA AGAACTGCTG 
TCCAATATGG GTCCCTTCTA CTTGATGGCC AAGGAAGCCG GCATTGAAAG TGTGAACCAC 
ACGGAGCTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abcc2 ( XM_006526625.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006526688.1 Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (Abcc2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu55214
Clone ID Related Accession (Same CDS sequence)	XM_006526625.4 , XM_006526625.3
Accession Version	XM_006526625.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4488bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	canalicular multispecific organic anion transporter 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000085.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006526625.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGTGG CAGCGCTGAG TCAGAGCAAG AGGTACAGAA AAACAAAGGA GCTCAAACCA 
GTGTTCGTTG TGTGTCTTCT TATTTTAGCA GCCATAGACC TGTCTCTTGC ACTCACAGAA 
GATACTGGAC AAGCCACAAT TCCTCCTGTT AAATATACAA ATCCAATTCT CTACCTATGC 
ACTTGGCTCC TGGTGTTGGT GATCCAACAC TGCAGGCAAT GCTGTATACA GAAGAATTCT 
TGGTTCCTGT CCATGTTCTG GATTCTCTCT CTATTATGTG GCATATTCCA GTTTCAGACT 
CTGATACGAG CACTCCTGCA GGATAGCAAG TCCAACATGA CCTATTCCTG CCTGTTCTTC 
GTCTCCTATG GTTTCCAGAT TGTCATTTTG ATCCTTTCAG CCTTTTCAGA ATCAAGCGAC 
TCAACACACG CCCCATCAGC TACAGCTTCA TTTCTGAGTA GCGTTACGTT TAGTTGGTAT 
GACAGCACTG TTCTGAAAGG TTACAAGCAT CCATTGACAA TAGAAGATGT GTGGGATATT 
GAAGAAAATC TTAAAGCCAA GTCACTCACC AGCAAGTTTA AGACGATCAT GACAAAGGAC 
CTGCAGAAAG CCAGGCAGGC TCTTCAGAGG CGGCTGAAGA AGTCCCAGCA GAGCCCTGAG 
GGCACGTCAC ACGGATTGAC CAAGAAGCAG AGTCAGAGCC AAGATGTCCT TGTCCTGGAA 
GACTCGAAAA AGAAGAAAAA GAAGTCTGAG GCCACCAAAG ACTTTCCCAA ATCCTGGTTG 
GTGAAGGCTC TCTTCAAAAC GTTCTACGTG GTGATCCTGA AGTCATTTAT TCTGAAATTA 
GCACATGATA TTCTTTTGTT TCTGAATCCT CAGCTGCTGA AATTTCTCAT TGGCTTCGTG 
AAAGACCCTG ACTCATATCC GTGGGTTGGA TATATCTATG CAATCCTAAT GTTCTCTGTG 
ACTCTCATCC AGTCTTTCTT CCTTCAGTGT TATTTTCAAT TTTGTTTTGT GTTGGGAATG 
ACTGTACGGA CAACCATCAT AGCTTCCGTA TATAAGAAGG CACTAACCCT ATCTAACTTG 
GCTAGGAGGC AGTACACGAT TGGAGAGACG GTGAACTTGA TGTCTGTAGA TTCCCAGAAG 
CTAATGGACG TGACCAACTA CATACACTTG CTGTGGTCCA GTGTTTTACA GATTGCTTTG 
TCCATTTTCT TCCTGTGGAG AGAGTTGGGA CCTTCGATTT TAGCAGGTGT TGGGCTTATG 
GTTCTCCTGG TCCCAGTTAA TGGCGTCCTG GCTACCAAGA TCAGGAAAAT TCAGGTCCAG 
AATATGAAGA ATAAAGACAA ACGCTTAAAA ATCATGAATG AGATTCTTAG TGGGATTAAG 
ATCCTGAAAT ACTTTGCCTG GGAACCTTCC TTTAAAGAGC AAGTGAACAG CATTCGGAAG 
AAAGAACTCA GGAACTTGCT GCGCTTCAGC CAGCTGCAGA CGATTTTGAT TTTCATCTTA 
CACCTAACTC CAACCCTGGT GTCCGTGATC ACATTTTCTG TTTACGTCCT GGTGGATAGT 
CAAAATGTTT TGAACGCGGA GAAGGCTTTC ACCTCCATCA CCCTCTTCAA TATCCTGCGC 
TTTCCTCTGG CCATGCTTCC CATGGTGATC TCTTCAGTCA TCCAGGCCAG CGTCTCTGTA 
GACCGGCTGG AGCAGTACCT GGGAAGCGAT GATCTGGACT TGTCTGCCAT TCGCCATGTC 
TGCCATTTTG ATAAAGCTGT GCAGTTCTCA GAAGCCTCTT TTACTTGGGA CCGGGACTTG 
GAAGCCACAA TCCAAGATGT GAACCTGGAC ATAAAACCAG GCCAACTGGT GGCTGTGGTG 
GGCACTGTAG GCTCTGGGAA GTCCTCTTTG ATATCAGCCA TGCTGGGAGA AATGGAGAAT 
GTCCATGGGC ATATCACCAT CAAGGGCTCC ATAGCCTACG TCCCTCAGCA GGCCTGGATT 
CAGAACGGGA CCATCAAAGA TAACATCCTG TTTGGGTCAG AATACGATGA AAAGAAGTAC 
CAGCGAGTTA TCGAAGCGTG CGCTCTCCTC CCAGACTTGG AAATGTTGCC TGGAGGAGAC 
ATGGCTGAGA TCGGAGAGAA GGGTATAAAT CTCAGTGGCG GTCAGAAGCA TCGAGTCAGC 
CTGGCCCGGG CCACCTATCA AGATGCAGAC ATCTATATTC TAGACGACCC CCTGTCGGCT 
GTGGACACTC ACGTGGGAAA ACACATTTTC AACAAGGTTG TGGGCCCCAA TGGCCTGCTG 
AGCGGCAAGA CTCGGATCTT GGTTACACAT GGCATTCACT TCCTTCCCCA AGTGGATGAG 
ATTGTCGTTC TGGGGAAAGG CACCATCTTA GAGAAGGGAT CCTATAGTGA CCTGATGGAC 
AAGAAAGGAG TGTTCGCTAA GAACTGGAAG ACATTCATGA AGCATTCGGG ACCTGAAGGA 
GAGGCTACAG TCGATAACGA CAGTGAGGAA GAGGATGGTG ACTGTGGGCT GATCCCAACT 
GTGGAGGAAA TTCCTGACGA TGCAGCTTCC TTGACCATGA GAAGGGAGAA CAGCCTTCGC 
CGAACACTGA GCCGCAGCTC TAGGTCCGGC AGCAGGCGTG GGAAGTCCCT CAAAAGCTCC 
TTGAAAATTA AAAGTGTGAA TGCCTTGAAT AAGAAGGAGG AAGTAGTGAA AGGACAAAAA 
CTAATTAAGA AGGAATTTGT GGAAACTGGG AAGGTAAAGT TCTCCATCTA CCTGAAATAT 
CTGCAGGCGG TAGGATGGTG GTCCCTGCTC TTCATCGTCA TCTTCTACGT ATTGAACTAT 
GTGGCTTTTA TTGGCACTAA CCTCTGGCTG AGTGCTTGGA CCAGTGACTC TGAAAAACAG 
AATGGGACCG ACAATTCACC TTCTCAGAGG GACATGAGAA TCGGGGTCTT TGGAGCTCTG 
GGAATAGCAC AAGGTATATT TTTGCTTAGT TCAAGTCTAT GGAGTATATA TGCTTGCAGA 
AATGCATCCA AAACTTTGCA CAGGCAGCTG TTAACCAACA TTCTCCGCGC ACCCATGAGT 
TTTTTTGACA CAACTCCCAC AGGCCGGATT GTGAACAGAT TTGCCGGGGA TATTTCTACG 
GTGGACGACA CACTCCCCCA GACTTTGCGA AGCTGGCTGC TGTGTTTCTT CGGCATAGTT 
AGCACTCTCG TGATGATCTG CATGGCCACC CCCATCTTCA TCATCATCAT CATCCCTCTC 
AGCATTCTCT ATGTATCTGT GCAGGTGTTT TATGTGGCTA CATCCCGCCA GCTGAGACGG 
CTGGATTCTG TCACCAAATC TCCGATCTAT TCTCACTTTA GTGAGACTGT CTCTGGTTTG 
CCTGTTATTC GGGCCTTTGA GCACCAGCAG AGATTTCTAG CAAACAGTGA GAAGCAGATT 
GACACCAACC AGAAATGCGT CTTTTCCTGG ATTACCTCCA ACCGGTGGCT TGCCATTCGC 
CTGGAGCTGG TTGGAAACCT GATTGTCTTC TGCTCGGCCT TGCTTCTGGT TATTTATAAG 
AATTCCTTAA CCGGGGACAC TGTGGGCTTT GTTCTGTCCA ACGCCCTCAA CATCACACAA 
ACCCTGAACT GGCTAGTGAG GATGACGTCA GAAGTAGAGA CCAACATCGT GGCTGTTGAG 
CGAATAAATG AATACATAAA TGTGGATAAT GAGGCGCCGT GGGTGACCGA CAAGAAGCCT 
CCGGCAGATT GGCCCAAAAA AGGTGAGATC CAGTTCAACA ACTATCAAGT GCGGTATCGG 
CCGGAGCTGG ATCTGGTCCT GAAAGGGATT ACTTGTAACA TCAAGAGCAC CGAGAAGGTC 
GGTGTGGTGG GCAGGACCGG AGCTGGAAAA TCATCCCTCA CAAACTGCCT CTTCAGAATC 
TTAGAGTCTG CAGGTGGCCA GATCATCATT GATGGGATTG ATATTGCCTC CATTGGACTG 
CACGACCTTC GAGGGAGACT GACCATCATT CCCCAGGACC CCATTTTGTT CTCTGGGAAT 
CTGAGGATGA ATCTCGACCC TTTCAACAAA TACTCGGATG AGGAGATCTG GAGGGCCCTG 
GAATTGGCTC ATCTCAAATC CTTTGTGGCT GGCCTGCAAC TTGGGTTGCT CCATGAAGTG 
ACAGAGGGCG GTGACAACCT GAGCATAGGG CAGAGGCAGC TCCTATGCCT GGGTAGGGCC 
GTGCTTCGAA AATCCAAAAT CCTGGTCCTG GACGAAGCCA CAGCCGCAGT GGATCTAGAG 
ACGGATAGCC TCATTCAGAC GACCATCCGG AACGAGTTCT CCCAGTGCAC GGTCATCACT 
ATCGCACACA GGCTGCACAC CATCATGGAC AGTGACAAGA TAATGGTCCT AGACAGCGGC 
AAGATTGTTG AATACGGCAG TCCTGAAGAA CTGCTGTCCA ATATGGGTCC CTTCTACTTG 
ATGGCCAAGG AAGCCGGCAT TGAAAGTGTG AACCACACGG AGCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006526688.1
CDS	161..4648
Translation	MAVAALSQSKRYRKTKELKPVFVVCLLILAAIDLSLALTEDTGQATIPPVKYTNPILYLCTWLLVLVIQHCRQCCIQKNSWFLSMFWILSLLCGIFQFQTLIRALLQDSKSNMTYSCLFFVSYGFQIVILILSAFSESSDSTHAPSATASFLSSVTFSWYDSTVLKGYKHPLTIEDVWDIEENLKAKSLTSKFKTIMTKDLQKARQALQRRLKKSQQSPEGTSHGLTKKQSQSQDVLVLEDSKKKKKKSEATKDFPKSWLVKALFKTFYVVILKSFILKLAHDILLFLNPQLLKFLIGFVKDPDSYPWVGYIYAILMFSVTLIQSFFLQCYFQFCFVLGMTVRTTIIASVYKKALTLSNLARRQYTIGETVNLMSVDSQKLMDVTNYIHLLWSSVLQIALSIFFLWRELGPSILAGVGLMVLLVPVNGVLATKIRKIQVQNMKNKDKRLKIMNEILSGIKILKYFAWEPSFKEQVNSIRKKELRNLLRFSQLQTILIFILHLTPTLVSVITFSVYVLVDSQNVLNAEKAFTSITLFNILRFPLAMLPMVISSVIQASVSVDRLEQYLGSDDLDLSAIRHVCHFDKAVQFSEASFTWDRDLEATIQDVNLDIKPGQLVAVVGTVGSGKSSLISAMLGEMENVHGHITIKGSIAYVPQQAWIQNGTIKDNILFGSEYDEKKYQRVIEACALLPDLEMLPGGDMAEIGEKGINLSGGQKHRVSLARATYQDADIYILDDPLSAVDTHVGKHIFNKVVGPNGLLSGKTRILVTHGIHFLPQVDEIVVLGKGTILEKGSYSDLMDKKGVFAKNWKTFMKHSGPEGEATVDNDSEEEDGDCGLIPTVEEIPDDAASLTMRRENSLRRTLSRSSRSGSRRGKSLKSSLKIKSVNALNKKEEVVKGQKLIKKEFVETGKVKFSIYLKYLQAVGWWSLLFIVIFYVLNYVAFIGTNLWLSAWTSDSEKQNGTDNSPSQRDMRIGVFGALGIAQGIFLLSSSLWSIYACRNASKTLHRQLLTNILRAPMSFFDTTPTGRIVNRFAGDISTVDDTLPQTLRSWLLCFFGIVSTLVMICMATPIFIIIIIPLSILYVSVQVFYVATSRQLRRLDSVTKSPIYSHFSETVSGLPVIRAFEHQQRFLANSEKQIDTNQKCVFSWITSNRWLAIRLELVGNLIVFCSALLLVIYKNSLTGDTVGFVLSNALNITQTLNWLVRMTSEVETNIVAVERINEYINVDNEAPWVTDKKPPADWPKKGEIQFNNYQVRYRPELDLVLKGITCNIKSTEKVGVVGRTGAGKSSLTNCLFRILESAGGQIIIDGIDIASIGLHDLRGRLTIIPQDPILFSGNLRMNLDPFNKYSDEEIWRALELAHLKSFVAGLQLGLLHEVTEGGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRNEFSQCTVITIAHRLHTIMDSDKIMVLDSGKIVEYGSPEELLSNMGPFYLMAKEAGIESVNHTEL

Target ORF information:

RefSeq Version	XM_006526625.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (Abcc2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006526625.3

ORF Insert Sequence:

ATGGCTGTGG CAGCGCTGAG TCAGAGCAAG AGGTACAGAA AAACAAAGGA GCTCAAACCA 
GTGTTCGTTG TGTGTCTTCT TATTTTAGCA GCCATAGACC TGTCTCTTGC ACTCACAGAA 
GATACTGGAC AAGCCACAAT TCCTCCTGTT AAATATACAA ATCCAATTCT CTACCTATGC 
ACTTGGCTCC TGGTGTTGGT GATCCAACAC TGCAGGCAAT GCTGTATACA GAAGAATTCT 
TGGTTCCTGT CCATGTTCTG GATTCTCTCT CTATTATGTG GCATATTCCA GTTTCAGACT 
CTGATACGAG CACTCCTGCA GGATAGCAAG TCCAACATGA CCTATTCCTG CCTGTTCTTC 
GTCTCCTATG GTTTCCAGAT TGTCATTTTG ATCCTTTCAG CCTTTTCAGA ATCAAGCGAC 
TCAACACACG CCCCATCAGC TACAGCTTCA TTTCTGAGTA GCGTTACGTT TAGTTGGTAT 
GACAGCACTG TTCTGAAAGG TTACAAGCAT CCATTGACAA TAGAAGATGT GTGGGATATT 
GAAGAAAATC TTAAAGCCAA GTCACTCACC AGCAAGTTTA AGACGATCAT GACAAAGGAC 
CTGCAGAAAG CCAGGCAGGC TCTTCAGAGG CGGCTGAAGA AGTCCCAGCA GAGCCCTGAG 
GGCACGTCAC ACGGATTGAC CAAGAAGCAG AGTCAGAGCC AAGATGTCCT TGTCCTGGAA 
GACTCGAAAA AGAAGAAAAA GAAGTCTGAG GCCACCAAAG ACTTTCCCAA ATCCTGGTTG 
GTGAAGGCTC TCTTCAAAAC GTTCTACGTG GTGATCCTGA AGTCATTTAT TCTGAAATTA 
GCACATGATA TTCTTTTGTT TCTGAATCCT CAGCTGCTGA AATTTCTCAT TGGCTTCGTG 
AAAGACCCTG ACTCATATCC GTGGGTTGGA TATATCTATG CAATCCTAAT GTTCTCTGTG 
ACTCTCATCC AGTCTTTCTT CCTTCAGTGT TATTTTCAAT TTTGTTTTGT GTTGGGAATG 
ACTGTACGGA CAACCATCAT AGCTTCCGTA TATAAGAAGG CACTAACCCT ATCTAACTTG 
GCTAGGAGGC AGTACACGAT TGGAGAGACG GTGAACTTGA TGTCTGTAGA TTCCCAGAAG 
CTAATGGACG TGACCAACTA CATACACTTG CTGTGGTCCA GTGTTTTACA GATTGCTTTG 
TCCATTTTCT TCCTGTGGAG AGAGTTGGGA CCTTCGATTT TAGCAGGTGT TGGGCTTATG 
GTTCTCCTGG TCCCAGTTAA TGGCGTCCTG GCTACCAAGA TCAGGAAAAT TCAGGTCCAG 
AATATGAAGA ATAAAGACAA ACGCTTAAAA ATCATGAATG AGATTCTTAG TGGGATTAAG 
ATCCTGAAAT ACTTTGCCTG GGAACCTTCC TTTAAAGAGC AAGTGAACAG CATTCGGAAG 
AAAGAACTCA GGAACTTGCT GCGCTTCAGC CAGCTGCAGA CGATTTTGAT TTTCATCTTA 
CACCTAACTC CAACCCTGGT GTCCGTGATC ACATTTTCTG TTTACGTCCT GGTGGATAGT 
CAAAATGTTT TGAACGCGGA GAAGGCTTTC ACCTCCATCA CCCTCTTCAA TATCCTGCGC 
TTTCCTCTGG CCATGCTTCC CATGGTGATC TCTTCAGTCA TCCAGGCCAG CGTCTCTGTA 
GACCGGCTGG AGCAGTACCT GGGAAGCGAT GATCTGGACT TGTCTGCCAT TCGCCATGTC 
TGCCATTTTG ATAAAGCTGT GCAGTTCTCA GAAGCCTCTT TTACTTGGGA CCGGGACTTG 
GAAGCCACAA TCCAAGATGT GAACCTGGAC ATAAAACCAG GCCAACTGGT GGCTGTGGTG 
GGCACTGTAG GCTCTGGGAA GTCCTCTTTG ATATCAGCCA TGCTGGGAGA AATGGAGAAT 
GTCCATGGGC ATATCACCAT CAAGGGCTCC ATAGCCTACG TCCCTCAGCA GGCCTGGATT 
CAGAACGGGA CCATCAAAGA TAACATCCTG TTTGGGTCAG AATACGATGA AAAGAAGTAC 
CAGCGAGTTA TCGAAGCGTG CGCTCTCCTC CCAGACTTGG AAATGTTGCC TGGAGGAGAC 
ATGGCTGAGA TCGGAGAGAA GGGTATAAAT CTCAGTGGCG GTCAGAAGCA TCGAGTCAGC 
CTGGCCCGGG CCACCTATCA AGATGCAGAC ATCTATATTC TAGACGACCC CCTGTCGGCT 
GTGGACACTC ACGTGGGAAA ACACATTTTC AACAAGGTTG TGGGCCCCAA TGGCCTGCTG 
AGCGGCAAGA CTCGGATCTT GGTTACACAT GGCATTCACT TCCTTCCCCA AGTGGATGAG 
ATTGTCGTTC TGGGGAAAGG CACCATCTTA GAGAAGGGAT CCTATAGTGA CCTGATGGAC 
AAGAAAGGAG TGTTCGCTAA GAACTGGAAG ACATTCATGA AGCATTCGGG ACCTGAAGGA 
GAGGCTACAG TCGATAACGA CAGTGAGGAA GAGGATGGTG ACTGTGGGCT GATCCCAACT 
GTGGAGGAAA TTCCTGACGA TGCAGCTTCC TTGACCATGA GAAGGGAGAA CAGCCTTCGC 
CGAACACTGA GCCGCAGCTC TAGGTCCGGC AGCAGGCGTG GGAAGTCCCT CAAAAGCTCC 
TTGAAAATTA AAAGTGTGAA TGCCTTGAAT AAGAAGGAGG AAGTAGTGAA AGGACAAAAA 
CTAATTAAGA AGGAATTTGT GGAAACTGGG AAGGTAAAGT TCTCCATCTA CCTGAAATAT 
CTGCAGGCGG TAGGATGGTG GTCCCTGCTC TTCATCGTCA TCTTCTACGT ATTGAACTAT 
GTGGCTTTTA TTGGCACTAA CCTCTGGCTG AGTGCTTGGA CCAGTGACTC TGAAAAACAG 
AATGGGACCG ACAATTCACC TTCTCAGAGG GACATGAGAA TCGGGGTCTT TGGAGCTCTG 
GGAATAGCAC AAGGTATATT TTTGCTTAGT TCAAGTCTAT GGAGTATATA TGCTTGCAGA 
AATGCATCCA AAACTTTGCA CAGGCAGCTG TTAACCAACA TTCTCCGCGC ACCCATGAGT 
TTTTTTGACA CAACTCCCAC AGGCCGGATT GTGAACAGAT TTGCCGGGGA TATTTCTACG 
GTGGACGACA CACTCCCCCA GACTTTGCGA AGCTGGCTGC TGTGTTTCTT CGGCATAGTT 
AGCACTCTCG TGATGATCTG CATGGCCACC CCCATCTTCA TCATCATCAT CATCCCTCTC 
AGCATTCTCT ATGTATCTGT GCAGGTGTTT TATGTGGCTA CATCCCGCCA GCTGAGACGG 
CTGGATTCTG TCACCAAATC TCCGATCTAT TCTCACTTTA GTGAGACTGT CTCTGGTTTG 
CCTGTTATTC GGGCCTTTGA GCACCAGCAG AGATTTCTAG CAAACAGTGA GAAGCAGATT 
GACACCAACC AGAAATGCGT CTTTTCCTGG ATTACCTCCA ACCGGTGGCT TGCCATTCGC 
CTGGAGCTGG TTGGAAACCT GATTGTCTTC TGCTCGGCCT TGCTTCTGGT TATTTATAAG 
AATTCCTTAA CCGGGGACAC TGTGGGCTTT GTTCTGTCCA ACGCCCTCAA CATCACACAA 
ACCCTGAACT GGCTAGTGAG GATGACGTCA GAAGTAGAGA CCAACATCGT GGCTGTTGAG 
CGAATAAATG AATACATAAA TGTGGATAAT GAGGCGCCGT GGGTGACCGA CAAGAAGCCT 
CCGGCAGATT GGCCCAAAAA AGGTGAGATC CAGTTCAACA ACTATCAAGT GCGGTATCGG 
CCGGAGCTGG ATCTGGTCCT GAAAGGGATT ACTTGTAACA TCAAGAGCAC CGAGAAGGTC 
GGTGTGGTGG GCAGGACCGG AGCTGGAAAA TCATCCCTCA CAAACTGCCT CTTCAGAATC 
TTAGAGTCTG CAGGTGGCCA GATCATCATT GATGGGATTG ATATTGCCTC CATTGGACTG 
CACGACCTTC GAGGGAGACT GACCATCATT CCCCAGGACC CCATTTTGTT CTCTGGGAAT 
CTGAGGATGA ATCTCGACCC TTTCAACAAA TACTCGGATG AGGAGATCTG GAGGGCCCTG 
GAATTGGCTC ATCTCAAATC CTTTGTGGCT GGCCTGCAAC TTGGGTTGCT CCATGAAGTG 
ACAGAGGGCG GTGACAACCT GAGCATAGGG CAGAGGCAGC TCCTATGCCT GGGTAGGGCC 
GTGCTTCGAA AATCCAAAAT CCTGGTCCTG GACGAAGCCA CAGCCGCAGT GGATCTAGAG 
ACGGATAGCC TCATTCAGAC GACCATCCGG AACGAGTTCT CCCAGTGCAC GGTCATCACT 
ATCGCACACA GGCTGCACAC CATCATGGAC AGTGACAAGA TAATGGTCCT AGACAGCGGC 
AAGATTGTTG AATACGGCAG TCCTGAAGAA CTGCTGTCCA ATATGGGTCC CTTCTACTTG 
ATGGCCAAGG AAGCCGGCAT TGAAAGTGTG AACCACACGG AGCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Circadian Clock Is Involved in Regulation of Hepatobiliary Transport Mediated by Multidrug Resistance-Associated Protein 2.
Journal of pharmaceutical sciences106(9)2491-2498(2017 Sep)
Oh JH,Lee JH,Han DH,Cho S,Lee YJ

CFTR-associated ligand is a negative regulator of Mrp2 expression.
American journal of physiology. Cell physiology312(1)C40-C46(2017 Jan)
Li M,Soroka CJ,Harry K,Boyer JL

Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors.
Nature cell biology18(12)1269-1280(2016 Dec)
Kaminski MM,Tosic J,Kresbach C,Engel H,Klockenbusch J,M?ller AL,Pichler R,Grahammer F,Kretz O,Huber TB,Walz G,Arnold SJ,Lienkamp SS

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

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Abcc2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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