Cd59a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cd59a
Entrez Gene ID	12509
Full Name	CD59a antigen
Synonyms	AA987121,Cd59,protectin
General protein information	Preferred Names CD59a antigen Names CD59A glycoprotein CD59 antigen MAC-IP MAC-inhibitory protein MACIF membrane attack complex inhibition factor
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2 E2\|2 54.53 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006498651.3	XP_006498714.1	CD59A glycoprotein isoform X1
NM_007652.5	NP_031678.1	CD59A glycoprotein precursor
XM_006498650.4	XP_006498713.1	CD59A glycoprotein isoform X2
XM_006498651.4	XP_006498714.1	CD59A glycoprotein isoform X2
NM_001111060.2	NP_001104530.1	CD59A glycoprotein precursor
XM_030247036.1	XP_030102896.1	CD59A glycoprotein isoform X1
XM_006498650.3	XP_006498713.1	CD59A glycoprotein isoform X1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse.
Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A
Developmental biology423(2)170-188(2017 03)

Deficiency of the complement regulatory protein CD59 accelerates the development of diabetes-induced atherosclerosis in mice.
Liu F, Sahoo R, Ge X, Wu L, Ghosh P, Qin X, Halperin JA
Journal of diabetes and its complications31(2)311-317(2017 Feb)

Organization, evolution and functions of the human and mouse Ly6/uPAR family genes.
Loughner CL, Bruford EA, McAndrews MS, Delp EE, Swamynathan S, Swamynathan SK
Human genomics1010(2016 Apr)

Retinal Pre-Conditioning by CD59a Knockout Protects against Light-Induced Photoreceptor Degeneration.
Song D, Wilson B, Zhao L, Bhuyan R, Bandyopadhyay M, Lyubarsky A, Yu C, Li Y, Kanu L, Miwa T, Song WC, Finnemann SC, Rohrer B, Dunaief JL
PloS one11(11)e0166348(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Varicella-zoster virus infection upregulates host CD59 expression in a tissue-specific manner.
Title: Modulation of host CD59 expression by varicella-zoster virus in human xenografts in vivo.

This study support a role of Cd59a in controlling the innate immune status of the RPE-choroidal complex and emphasizes the particular vulnerability of this ocular compartment to the dysregulation of alternative complement pathway during aging
Title: Cd59a deficiency in mice leads to preferential innate immune activation in the retinal pigment epithelium-choroid with age.

results implicate CD59 as an important modulator of the immune response in NMO, and provide a novel animal model of NMO that closely recapitulates human NMO pathology.
Title: Longitudinally extensive NMO spinal cord pathology produced by passive transfer of NMO-IgG in mice lacking complement inhibitor CD59.

Soluble forms of CD59 (sCD59) have been investigated in mouse laser-induced choroidal neovascularization, a model for "wet" age related macular degeneration.
Title: The complement regulatory protein CD59: insights into attenuation of choroidal neovascularization.

both CD59 and C-PC could inhibit the progress of atherosclerosis, and the anti-atherosclerotic effects of C-PC might be fulfilled by promoting CD59 expression, preventing smooth muscle cell proliferation and the apoptosis of endothelial cells
Title: CD59 underlines the antiatherosclerotic effects of C-phycocyanin on mice.

The following Cd59a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cd59a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu19797	NM_001111060.2 Latest version!	Mus musculus CD59a antigen (Cd59a), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu19797	NM_007652.5 Latest version!	Mus musculus CD59a antigen (Cd59a), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu19797	XM_006498651.4 Latest version!	Mus musculus CD59a antigen (Cd59a), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu19797	XM_006498650.4 Latest version!	Mus musculus CD59a antigen (Cd59a), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu87679	XM_030247036.1 Latest version!	Mus musculus CD59a antigen (Cd59a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu19797	XM_006498651.3	Mus musculus CD59a antigen (Cd59a), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu19797	XM_006498650.3	Mus musculus CD59a antigen (Cd59a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cd59a ( NM_007652.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031678.1 Mus musculus CD59a antigen (Cd59a), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu19797
Clone ID Related Accession (Same CDS sequence)	XM_006498651.3 , NM_007652.5 , XM_006498650.4 , XM_006498651.4 , NM_001111060.2 , XM_006498650.3
Accession Version	NM_007652.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 372bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	CD59A glycoprotein precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY228038.1, AK005507.1, AK002743.1 and BY585575.1. On Oct 19, 2013 this sequence version replaced NM_007652.4. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK002743.1, AK018136.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGAGCTC AGAGGGGACT CATCTTACTC CTGCTGCTTC TGGCTGTGTT CTGTTCCACA 
GCTGTTAGCC TCACATGCTA CCACTGTTTC CAACCGGTGG TTTCTTCATG CAATATGAAC 
AGCACTTGCT CTCCTGACCA GGATTCCTGT CTCTATGCTG TAGCCGGAAT GCAAGTGTAT 
CAAAGGTGTT GGAAACAATC AGATTGTCAT GGTGAGATCA TTATGGACCA ATTAGAAGAG 
ACAAAATTAA AATTCAGATG CTGCCAGTTT AACTTGTGTA ACAAAAGTGA CGGATCCTTG 
GGGAAGACAC CATTGCTGGG GACCTCGGTT CTGGTGGCCA TTTTGAATCT TTGTTTCTTA 
AGTCATCTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031678.1
CDS	146..517
Translation	MRAQRGLILLLLLLAVFCSTAVSLTCYHCFQPVVSSCNMNSTCSPDQDSCLYAVAGMQVYQRCWKQSDCHGEIIMDQLEETKLKFRCCQFNLCNKSDGSLGKTPLLGTSVLVAILNLCFLSHL

Target ORF information:

RefSeq Version	NM_007652.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus CD59a antigen (Cd59a), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007652.5

ORF Insert Sequence:

ATGAGAGCTC AGAGGGGACT CATCTTACTC CTGCTGCTTC TGGCTGTGTT CTGTTCCACA 
GCTGTTAGCC TCACATGCTA CCACTGTTTC CAACCGGTGG TTTCTTCATG CAATATGAAC 
AGCACTTGCT CTCCTGACCA GGATTCCTGT CTCTATGCTG TAGCCGGAAT GCAAGTGTAT 
CAAAGGTGTT GGAAACAATC AGATTGTCAT GGTGAGATCA TTATGGACCA ATTAGAAGAG 
ACAAAATTAA AATTCAGATG CTGCCAGTTT AACTTGTGTA ACAAAAGTGA CGGATCCTTG 
GGGAAGACAC CATTGCTGGG GACCTCGGTT CTGGTGGCCA TTTTGAATCT TTGTTTCTTA 
AGTCATCTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cd59a ( NM_001111060.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001104530.1 Mus musculus CD59a antigen (Cd59a), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu19797
Clone ID Related Accession (Same CDS sequence)	XM_006498651.3 , NM_007652.5 , XM_006498650.4 , XM_006498651.4 , NM_001111060.2 , XM_006498650.3
Accession Version	NM_001111060.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 372bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	CD59A glycoprotein precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY228038.1, CA467821.1, AK005507.1, AK002743.1 and BY585575.1. On Oct 19, 2013 this sequence version replaced NM_001111060.1. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CA467821.1, BE655906.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGAGCTC AGAGGGGACT CATCTTACTC CTGCTGCTTC TGGCTGTGTT CTGTTCCACA 
GCTGTTAGCC TCACATGCTA CCACTGTTTC CAACCGGTGG TTTCTTCATG CAATATGAAC 
AGCACTTGCT CTCCTGACCA GGATTCCTGT CTCTATGCTG TAGCCGGAAT GCAAGTGTAT 
CAAAGGTGTT GGAAACAATC AGATTGTCAT GGTGAGATCA TTATGGACCA ATTAGAAGAG 
ACAAAATTAA AATTCAGATG CTGCCAGTTT AACTTGTGTA ACAAAAGTGA CGGATCCTTG 
GGGAAGACAC CATTGCTGGG GACCTCGGTT CTGGTGGCCA TTTTGAATCT TTGTTTCTTA 
AGTCATCTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001104530.1
CDS	266..637
Translation	MRAQRGLILLLLLLAVFCSTAVSLTCYHCFQPVVSSCNMNSTCSPDQDSCLYAVAGMQVYQRCWKQSDCHGEIIMDQLEETKLKFRCCQFNLCNKSDGSLGKTPLLGTSVLVAILNLCFLSHL

Target ORF information:

RefSeq Version	NM_001111060.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus CD59a antigen (Cd59a), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001111060.2

ORF Insert Sequence:

ATGAGAGCTC AGAGGGGACT CATCTTACTC CTGCTGCTTC TGGCTGTGTT CTGTTCCACA 
GCTGTTAGCC TCACATGCTA CCACTGTTTC CAACCGGTGG TTTCTTCATG CAATATGAAC 
AGCACTTGCT CTCCTGACCA GGATTCCTGT CTCTATGCTG TAGCCGGAAT GCAAGTGTAT 
CAAAGGTGTT GGAAACAATC AGATTGTCAT GGTGAGATCA TTATGGACCA ATTAGAAGAG 
ACAAAATTAA AATTCAGATG CTGCCAGTTT AACTTGTGTA ACAAAAGTGA CGGATCCTTG 
GGGAAGACAC CATTGCTGGG GACCTCGGTT CTGGTGGCCA TTTTGAATCT TTGTTTCTTA 
AGTCATCTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cd59a ( XM_006498651.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006498714.1 Mus musculus CD59a antigen (Cd59a), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu19797
Clone ID Related Accession (Same CDS sequence)	XM_006498651.3 , NM_007652.5 , XM_006498650.4 , XM_006498651.4 , NM_001111060.2 , XM_006498650.3
Accession Version	XM_006498651.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 372bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	CD59A glycoprotein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006498651.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGAGCTC AGAGGGGACT CATCTTACTC CTGCTGCTTC TGGCTGTGTT CTGTTCCACA 
GCTGTTAGCC TCACATGCTA CCACTGTTTC CAACCGGTGG TTTCTTCATG CAATATGAAC 
AGCACTTGCT CTCCTGACCA GGATTCCTGT CTCTATGCTG TAGCCGGAAT GCAAGTGTAT 
CAAAGGTGTT GGAAACAATC AGATTGTCAT GGTGAGATCA TTATGGACCA ATTAGAAGAG 
ACAAAATTAA AATTCAGATG CTGCCAGTTT AACTTGTGTA ACAAAAGTGA CGGATCCTTG 
GGGAAGACAC CATTGCTGGG GACCTCGGTT CTGGTGGCCA TTTTGAATCT TTGTTTCTTA 
AGTCATCTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006498714.1
CDS	235..606
Translation	MRAQRGLILLLLLLAVFCSTAVSLTCYHCFQPVVSSCNMNSTCSPDQDSCLYAVAGMQVYQRCWKQSDCHGEIIMDQLEETKLKFRCCQFNLCNKSDGSLGKTPLLGTSVLVAILNLCFLSHL

Target ORF information:

RefSeq Version	XM_006498651.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus CD59a antigen (Cd59a), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006498651.3

ORF Insert Sequence:

ATGAGAGCTC AGAGGGGACT CATCTTACTC CTGCTGCTTC TGGCTGTGTT CTGTTCCACA 
GCTGTTAGCC TCACATGCTA CCACTGTTTC CAACCGGTGG TTTCTTCATG CAATATGAAC 
AGCACTTGCT CTCCTGACCA GGATTCCTGT CTCTATGCTG TAGCCGGAAT GCAAGTGTAT 
CAAAGGTGTT GGAAACAATC AGATTGTCAT GGTGAGATCA TTATGGACCA ATTAGAAGAG 
ACAAAATTAA AATTCAGATG CTGCCAGTTT AACTTGTGTA ACAAAAGTGA CGGATCCTTG 
GGGAAGACAC CATTGCTGGG GACCTCGGTT CTGGTGGCCA TTTTGAATCT TTGTTTCTTA 
AGTCATCTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cd59a ( XM_006498650.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006498713.1 Mus musculus CD59a antigen (Cd59a), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu19797
Clone ID Related Accession (Same CDS sequence)	XM_006498651.3 , NM_007652.5 , XM_006498650.4 , XM_006498651.4 , NM_001111060.2 , XM_006498650.3
Accession Version	XM_006498650.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 372bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	CD59A glycoprotein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006498650.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGAGCTC AGAGGGGACT CATCTTACTC CTGCTGCTTC TGGCTGTGTT CTGTTCCACA 
GCTGTTAGCC TCACATGCTA CCACTGTTTC CAACCGGTGG TTTCTTCATG CAATATGAAC 
AGCACTTGCT CTCCTGACCA GGATTCCTGT CTCTATGCTG TAGCCGGAAT GCAAGTGTAT 
CAAAGGTGTT GGAAACAATC AGATTGTCAT GGTGAGATCA TTATGGACCA ATTAGAAGAG 
ACAAAATTAA AATTCAGATG CTGCCAGTTT AACTTGTGTA ACAAAAGTGA CGGATCCTTG 
GGGAAGACAC CATTGCTGGG GACCTCGGTT CTGGTGGCCA TTTTGAATCT TTGTTTCTTA 
AGTCATCTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006498713.1
CDS	296..667
Translation	MRAQRGLILLLLLLAVFCSTAVSLTCYHCFQPVVSSCNMNSTCSPDQDSCLYAVAGMQVYQRCWKQSDCHGEIIMDQLEETKLKFRCCQFNLCNKSDGSLGKTPLLGTSVLVAILNLCFLSHL

Target ORF information:

RefSeq Version	XM_006498650.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus CD59a antigen (Cd59a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006498650.3

ORF Insert Sequence:

ATGAGAGCTC AGAGGGGACT CATCTTACTC CTGCTGCTTC TGGCTGTGTT CTGTTCCACA 
GCTGTTAGCC TCACATGCTA CCACTGTTTC CAACCGGTGG TTTCTTCATG CAATATGAAC 
AGCACTTGCT CTCCTGACCA GGATTCCTGT CTCTATGCTG TAGCCGGAAT GCAAGTGTAT 
CAAAGGTGTT GGAAACAATC AGATTGTCAT GGTGAGATCA TTATGGACCA ATTAGAAGAG 
ACAAAATTAA AATTCAGATG CTGCCAGTTT AACTTGTGTA ACAAAAGTGA CGGATCCTTG 
GGGAAGACAC CATTGCTGGG GACCTCGGTT CTGGTGGCCA TTTTGAATCT TTGTTTCTTA 
AGTCATCTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cd59a ( XM_006498650.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006498713.1 Mus musculus CD59a antigen (Cd59a), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu19797
Clone ID Related Accession (Same CDS sequence)	XM_006498651.3 , NM_007652.5 , XM_006498650.4 , XM_006498651.4 , NM_001111060.2 , XM_006498650.3
Accession Version	XM_006498650.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 372bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	CD59A glycoprotein isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006498650.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGAGCTC AGAGGGGACT CATCTTACTC CTGCTGCTTC TGGCTGTGTT CTGTTCCACA 
GCTGTTAGCC TCACATGCTA CCACTGTTTC CAACCGGTGG TTTCTTCATG CAATATGAAC 
AGCACTTGCT CTCCTGACCA GGATTCCTGT CTCTATGCTG TAGCCGGAAT GCAAGTGTAT 
CAAAGGTGTT GGAAACAATC AGATTGTCAT GGTGAGATCA TTATGGACCA ATTAGAAGAG 
ACAAAATTAA AATTCAGATG CTGCCAGTTT AACTTGTGTA ACAAAAGTGA CGGATCCTTG 
GGGAAGACAC CATTGCTGGG GACCTCGGTT CTGGTGGCCA TTTTGAATCT TTGTTTCTTA 
AGTCATCTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006498713.1
CDS	291..662
Translation	MRAQRGLILLLLLLAVFCSTAVSLTCYHCFQPVVSSCNMNSTCSPDQDSCLYAVAGMQVYQRCWKQSDCHGEIIMDQLEETKLKFRCCQFNLCNKSDGSLGKTPLLGTSVLVAILNLCFLSHL

Target ORF information:

RefSeq Version	XM_006498650.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus CD59a antigen (Cd59a), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006498650.4

ORF Insert Sequence:

ATGAGAGCTC AGAGGGGACT CATCTTACTC CTGCTGCTTC TGGCTGTGTT CTGTTCCACA 
GCTGTTAGCC TCACATGCTA CCACTGTTTC CAACCGGTGG TTTCTTCATG CAATATGAAC 
AGCACTTGCT CTCCTGACCA GGATTCCTGT CTCTATGCTG TAGCCGGAAT GCAAGTGTAT 
CAAAGGTGTT GGAAACAATC AGATTGTCAT GGTGAGATCA TTATGGACCA ATTAGAAGAG 
ACAAAATTAA AATTCAGATG CTGCCAGTTT AACTTGTGTA ACAAAAGTGA CGGATCCTTG 
GGGAAGACAC CATTGCTGGG GACCTCGGTT CTGGTGGCCA TTTTGAATCT TTGTTTCTTA 
AGTCATCTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cd59a ( XM_006498651.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006498714.1 Mus musculus CD59a antigen (Cd59a), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu19797
Clone ID Related Accession (Same CDS sequence)	XM_006498651.3 , NM_007652.5 , XM_006498650.4 , XM_006498651.4 , NM_001111060.2 , XM_006498650.3
Accession Version	XM_006498651.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 372bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	CD59A glycoprotein isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006498651.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGAGCTC AGAGGGGACT CATCTTACTC CTGCTGCTTC TGGCTGTGTT CTGTTCCACA 
GCTGTTAGCC TCACATGCTA CCACTGTTTC CAACCGGTGG TTTCTTCATG CAATATGAAC 
AGCACTTGCT CTCCTGACCA GGATTCCTGT CTCTATGCTG TAGCCGGAAT GCAAGTGTAT 
CAAAGGTGTT GGAAACAATC AGATTGTCAT GGTGAGATCA TTATGGACCA ATTAGAAGAG 
ACAAAATTAA AATTCAGATG CTGCCAGTTT AACTTGTGTA ACAAAAGTGA CGGATCCTTG 
GGGAAGACAC CATTGCTGGG GACCTCGGTT CTGGTGGCCA TTTTGAATCT TTGTTTCTTA 
AGTCATCTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006498714.1
CDS	230..601
Translation	MRAQRGLILLLLLLAVFCSTAVSLTCYHCFQPVVSSCNMNSTCSPDQDSCLYAVAGMQVYQRCWKQSDCHGEIIMDQLEETKLKFRCCQFNLCNKSDGSLGKTPLLGTSVLVAILNLCFLSHL

Target ORF information:

RefSeq Version	XM_006498651.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus CD59a antigen (Cd59a), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006498651.4

ORF Insert Sequence:

ATGAGAGCTC AGAGGGGACT CATCTTACTC CTGCTGCTTC TGGCTGTGTT CTGTTCCACA 
GCTGTTAGCC TCACATGCTA CCACTGTTTC CAACCGGTGG TTTCTTCATG CAATATGAAC 
AGCACTTGCT CTCCTGACCA GGATTCCTGT CTCTATGCTG TAGCCGGAAT GCAAGTGTAT 
CAAAGGTGTT GGAAACAATC AGATTGTCAT GGTGAGATCA TTATGGACCA ATTAGAAGAG 
ACAAAATTAA AATTCAGATG CTGCCAGTTT AACTTGTGTA ACAAAAGTGA CGGATCCTTG 
GGGAAGACAC CATTGCTGGG GACCTCGGTT CTGGTGGCCA TTTTGAATCT TTGTTTCTTA 
AGTCATCTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cd59a ( XM_030247036.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030102896.1 Mus musculus CD59a antigen (Cd59a), transcript variant X1, mRNA.

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CloneID	OMu87679
Clone ID Related Accession (Same CDS sequence)	XM_030247036.1
Accession Version	XM_030247036.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 666bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	CD59A glycoprotein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCTG CTGCTATGCT TCTGCTTCTG CTTCTGCTGC TGCTGCTGCT CCTGCTCCTC 
CTCCTCCTCC TGCTCCTGCT CCTGCTCCTG CTGCTGCTCC TGCTCCTGCT CCTGCTCCTG 
CTCCTGCTCC TGCTCCTGCT CCTGCTCCTG CTGCTGCTCC TGCTGCTGCT GCTGCTGCTG 
CTCCTGCTCC TGCTCCTGCT CCTGCTCCTG CTCCTGCTCC TGCTCCTGCT CCTGCTCCTG 
CTCCTGCTCC TGCTCCTCCT CCTCCTCCTG CTCCTGCTCC TGCTCCTGCT CCTGCTCCTG 
CTCCTGCTCC TGCTCCTGCT CCTGCTCCTG CTCCTGCTCC TGCTCCTGCT CCTGCTCCTG 
CTCCTCCTCC TCCTCCTCCT GCTCCTGCTC CTGCTGCTGC TCCTGCTCCT GCTCCTGCTC 
CTGCTCCTGC TCCTGCTCCT CCTCCTGCTC CTCCTCCTCC TCCTCCTCCT GCTCCTGCTC 
CTCCTCCTCC TTTCCCCTCC CCCTTCCTCG TCCTCCTCCT CTTCCATCTC TATCTTCTTC 
TTCCTCTTCT TTTTGTTCAT GGTTCTTTGT AAATTTCACA TCATGTACCC CAATCCCACT 
CATCTCTCCC TCCTCTCTTA CCCACCTTCC TCCACCTTTG TAACCTCCCT GTTGTGGAAG 
CTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030102896.1
CDS	326..991
Translation	MAAAAMLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLSPPPSSSSSSSISIFFFLFFLFMVLCKFHIMYPNPTHLSLLSYPPSSTFVTSLLWKL

Target ORF information:

RefSeq Version	XM_030247036.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus CD59a antigen (Cd59a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030247036.1

ORF Insert Sequence:

ATGGCGGCTG CTGCTATGCT TCTGCTTCTG CTTCTGCTGC TGCTGCTGCT CCTGCTCCTC 
CTCCTCCTCC TGCTCCTGCT CCTGCTCCTG CTGCTGCTCC TGCTCCTGCT CCTGCTCCTG 
CTCCTGCTCC TGCTCCTGCT CCTGCTCCTG CTGCTGCTCC TGCTGCTGCT GCTGCTGCTG 
CTCCTGCTCC TGCTCCTGCT CCTGCTCCTG CTCCTGCTCC TGCTCCTGCT CCTGCTCCTG 
CTCCTGCTCC TGCTCCTCCT CCTCCTCCTG CTCCTGCTCC TGCTCCTGCT CCTGCTCCTG 
CTCCTGCTCC TGCTCCTGCT CCTGCTCCTG CTCCTGCTCC TGCTCCTGCT CCTGCTCCTG 
CTCCTCCTCC TCCTCCTCCT GCTCCTGCTC CTGCTGCTGC TCCTGCTCCT GCTCCTGCTC 
CTGCTCCTGC TCCTGCTCCT CCTCCTGCTC CTCCTCCTCC TCCTCCTCCT GCTCCTGCTC 
CTCCTCCTCC TTTCCCCTCC CCCTTCCTCG TCCTCCTCCT CTTCCATCTC TATCTTCTTC 
TTCCTCTTCT TTTTGTTCAT GGTTCTTTGT AAATTTCACA TCATGTACCC CAATCCCACT 
CATCTCTCCC TCCTCTCTTA CCCACCTTCC TCCACCTTTG TAACCTCCCT GTTGTGGAAG 
CTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse.
Developmental biology423(2)170-188(2017 03)
Stauber M,Weidemann M,Dittrich-Breiholz O,Lobschat K,Alten L,Mai M,Beckers A,Kracht M,Gossler A

Deficiency of the complement regulatory protein CD59 accelerates the development of diabetes-induced atherosclerosis in mice.
Journal of diabetes and its complications31(2)311-317(2017 Feb)
Liu F,Sahoo R,Ge X,Wu L,Ghosh P,Qin X,Halperin JA

Organization, evolution and functions of the human and mouse Ly6/uPAR family genes.
Human genomics1010(2016 Apr)
Loughner CL,Bruford EA,McAndrews MS,Delp EE,Swamynathan S,Swamynathan SK

Retinal Pre-Conditioning by CD59a Knockout Protects against Light-Induced Photoreceptor Degeneration.
PloS one11(11)e0166348(2016)
Song D,Wilson B,Zhao L,Bhuyan R,Bandyopadhyay M,Lyubarsky A,Yu C,Li Y,Kanu L,Miwa T,Song WC,Finnemann SC,Rohrer B,Dunaief JL

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Cd59a cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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