gRNAs
The following Arc gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Arc cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu23183 | |
| Clone ID Related Accession (Same CDS sequence) | NM_018790.3 , NM_001276684.1 | |
| Accession Version | NM_018790.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1191bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-27 | |
| Organism | Mus musculus(house mouse) | |
| Product | activity-regulated cytoskeleton-associated protein | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC118022.12 and AF162777.1. On Feb 21, 2013 this sequence version replaced NM_018790.2. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. CCDS Note: This CCDS ID represents the protein described in PMIDs: 10727859 and 22036569. This protein is encoded by two splice variants which are supported by AK157822.1 and AF162777.1. It should be noted this transcript is predicted to undergo nonsense-mediated mRNA decay (NMD). However, the protein is represented because it was detected endogenously in PMID: 22036569. It is likely that the majority of transcripts representing this variant will undergo NMD, while some low level of NMD escape may allow for the expression of this protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660817.6665.1, AF162777.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## NMD candidate :: PMID: 22036569 ##RefSeq-Attributes-END## | |
1 | ATGGAGCTGG ACCATATGAC CACCGGCGGC CTCCACGCCT ACCCTGCCCC GCGGGGTGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_061260.1 |
| CDS | 199..1389 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_018790.3 |
1 | ATGGAGCTGG ACCATATGAC CACCGGCGGC CTCCACGCCT ACCCTGCCCC GCGGGGTGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu23183 | |
| Clone ID Related Accession (Same CDS sequence) | NM_018790.3 , NM_001276684.1 | |
| Accession Version | NM_001276684.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1191bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-27 | |
| Organism | Mus musculus(house mouse) | |
| Product | activity-regulated cytoskeleton-associated protein | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK157822.1 and AC118022.12. Transcript Variant: This variant (2) uses an alternate splice site in the 3' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. CCDS Note: This CCDS ID represents the protein described in PMIDs: 10727859 and 22036569. This protein is encoded by two splice variants which are supported by AK157822.1 and AF162777.1. It should be noted this transcript is predicted to undergo nonsense-mediated mRNA decay (NMD). However, the protein is represented because it was detected endogenously in PMID: 22036569. It is likely that the majority of transcripts representing this variant will undergo NMD, while some low level of NMD escape may allow for the expression of this protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK157822.1, BC023127.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849384 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## NMD candidate :: PMID: 22036569 ##RefSeq-Attributes-END## | |
1 | ATGGAGCTGG ACCATATGAC CACCGGCGGC CTCCACGCCT ACCCTGCCCC GCGGGGTGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001263613.1 |
| CDS | 199..1389 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001276684.1 |
1 | ATGGAGCTGG ACCATATGAC CACCGGCGGC CTCCACGCCT ACCCTGCCCC GCGGGGTGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Arc/Arg3.1 regulates an endosomal pathway essential for activity-dependent ?-amyloid generation. |
