Adam4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Adam4
Entrez Gene ID	11498
Full Name	a disintegrin and metallopeptidase domain 4
Synonyms	AV274654,tMDCV
General protein information	Preferred Names a disintegrin and metallopeptidase domain 4 Names a disintegrin and metallopeptidase domain 4 a disintegrin and metalloprotease domain (ADAM) 4 a disintegrin and metalloprotease domain 4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 12 Map Location: 12\|12 D1

mRNA and Protein(s)

mRNA	Protein	Name
NM_009620.2	NP_033750.1	a disintegrin and metallopeptidase domain 4 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LOC467495	XP_001145615.1
	LOC713632	XP_001111189.1
Canis lupus familiaris (dog)	LOC100682819	XP_003435133.1
Bos taurus (cattle)	LOC615247	XP_002691091.1
Mus musculus (house mouse)	Gm4787	NP_001034084.2
Rattus norvegicus (Norway rat)	Adam4	NP_064701.1
Rattus norvegicus (Norway rat)	Adam4l1	NP_001102747.1
	LOC713573	XP_001111151.1
Mus musculus (house mouse)	Adam4	NP_033750.1

Gene Ontology
Bibliography

Related articles in PubMed

Comprehensive analysis of reproductive ADAMs: relationship of ADAM4 and ADAM6 with an ADAM complex required for fertilization in mice.
Han C, Choi E, Park I, Lee B, Jin S, Kim DH, Nishimura H, Cho C
Biology of reproduction80(5)1001-8(2009 May)

New quantitative trait loci that regulate wound healing in an intercross progeny from DBA/1J and 129 x 1/SvJ inbred strains of mice.
Masinde GL, Li R, Nguyen B, Yu H, Srivastava AK, Edderkaoui B, Wergedal JE, Baylink DJ, Mohan S
Functional & integrative genomics6(2)157-63(2006 Apr)

Characterization and comparative genomic analysis of intronless Adams with testicular gene expression.
Choi I, Oh J, Cho BN, Ahnn J, Jung YK, Han Kim D, Cho C
Genomics83(4)636-46(2004 Apr)

Interacting QTLs for cholesterol gallstones and gallbladder mucin in AKR and SWR strains of mice.
Wittenburg H, Lammert F, Wang DQ, Churchill GA, Li R, Bouchard G, Carey MC, Paigen B
Physiological genomics8(1)67-77(2002 Feb)

Impaired motor coordination in mice that lack punc.
Yang W, Li C, Mansour SL
Molecular and cellular biology21(17)6031-43(2001 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The levels of ADAM4 and ADAM6 are dramatically reduced in Adam2 and Adam3 knockout sperm defective in various fertilization processes. We observed premature processing of ADAM4 in the Adam3-null mice.
Title: Comprehensive analysis of reproductive ADAMs: relationship of ADAM4 and ADAM6 with an ADAM complex required for fertilization in mice.

The following Adam4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Adam4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu76889	NM_009620.2 Latest version!	Mus musculus a disintegrin and metallopeptidase domain 4 (Adam4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Adam4 ( NM_009620.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033750.1 Mus musculus a disintegrin and metallopeptidase domain 4 (Adam4), mRNA.

Price & Availability↑

CloneID	OMu76889
Clone ID Related Accession (Same CDS sequence)	NM_009620.2
Accession Version	NM_009620.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2292bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-25
Organism	Mus musculus(house mouse)
Product	a disintegrin and metallopeptidase domain 4 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BE956537.1, AC132391.3, BF458290.1, BC150481.1, AV264697.1 and AV274654.1. On Nov 17, 2015 this sequence version replaced NM_009620.1.

ATGGCTCCCT TCCTCAGACC ATCTACCTGG ACTTTGGCCC TCCTGAGAGG TGCTCTCTGG 
CTCTCTGTGC TCTGGGCACT GTTGTCTCCT GCCTGCTGTT CCCGTAGCCC ACCCAAATGG 
CGCTTCTCTA CCTCTGAAAT TGTCATCCCC AGGAAGGTTC CCCAGAGAAT GGGCAAAAGT 
GATATGTCTG GGCACATCAC CTATAGCATG CGCTTTAGGG GACAAAGACA TGTGGTCCAC 
ATGAAACTCA AGAAAAACAT GATTCCTCAA AATTTTCCTG TATATACCTC TAATGACCAA 
GGAGCCCAAC AGAAGGATTA CCCATTTGTT CCTCGGGATT GTTACTTCTA CAGCTTCCTG 
GAAGGAGTCC CTGGGTCCCA AGCTATACTA GATACCTGTA CTGGAGGTCT GAAAGGCATG 
ATACAGGTGG ATGACTTCAC TTATGAAATC AAACCATTGG CATCTTCTTC CAAATTTGAG 
CATGTAATTT CTCTGCTTGT GGTGGATGAA AGGTCACGTG AGTCAAAAAA GTGTAGAAAT 
GATGAGATTA TGGCAAAGGC AGGTGACCTC TCTGAAGAGA CCAAGCTGGC TGGAAGTCCC 
AGAGCAGCCC CTGTATATCT GTGGCGTTAC CATTTGAAAA GTGTAGGAAT ACACTACACG 
GTGACTCATG ACTTATTCAA ACAAACTGGG AGCAATTCCT CCACCTCAGT TGAGTTAATA 
CTGATTATGA ATAGCATTTC AGATAGCATT TATAAAATAA GTGGATTGAT TGTGTATGCA 
CGTGGTGTAT GGATTTGGAA TACGAAGAAC CTGCATACTG TCCCCGGTGA AAATCCCCAC 
CTTGATCCTT GGAGTGTTAT GGCAGGTTTT GGTGTATGGA AATCTAAAGA ATTGCACGAT 
TTGTATGCCA CTACAGCTAT TCTCCTTGCA TCAAGACCAA AAAATACAGA TTATGGAAGC 
TTTCAGAATG GATTATGTAA CCCCAACTGG GGAGTATTAT TTACATATGT AGGAAAAAAC 
CATTTATTTC TGGCTGGATC TTTCCTGGCA CATGCAGTGG GTCACCTTTT AGATGTAAGC 
CATGATACAC CAGGCTGTGT TTGTTTCAGA AGGAGCAGTT GTCTCATGGA TGAATTTCCT 
ACTCTTCATG ATATGATTAG TAATTGTTCC CATAATGAGT TACATAGGAG GATCCATGAC 
TGGGACCCTT GCTTGAGTTT AGAGCTAAAA ACAGCTAAAG AAGTAAACAT GTATGAAGTT 
CCTCGTTGTG GAAATAAGAG AGTGGAGGCC AGTGAGAAAT GTGACTGTGG TTCTGTGAAA 
GACTGTACCA CTGATAAGTG TTGTGAAGTC AATTGTGAGT TTACTCAGGG TAGCTCTTGT 
GCTGCAGGAG GTTGCTGTCT ATCTTGTAAG TTTGCACCCA CTGGAACAAT ATGCAGAGAC 
AAAAATGGTA TTTGTGATCT TCCAGAGTAC TGTAGTGGAG CCTCAGAGCA TTGCCCAGGA 
AATTTTTACA TCATGGATGG AACTCCTTGT TCTCCACTGG CAGTCTGCAT AGCAGGAAAC 
TGTAGTGACC GTCATTTGCA GTGTCAAGCT CTTTTTGGAT ACCAAGTAAA GGATGGTTCA 
CCAGCATGCT ATAATGAATT AAATGTCAAA GGTGACCGAT TTGGAAACTG TGGCATTAGA 
ATCATACGTG GAGGAAGCCA ACCTGTCCCA TGTCAAAAGG AGGATGTTTT TTGTGGAATG 
ATCCACTGTG ATGGTGTCAG TCATATTCCT GGTGGAGGTG AGCACACTAC CTTTTATCAC 
CTAAAGGTTC AAGATGTTAA AGAAGAACAG TGCTTTGGGT ATGATGCACA CCATGGGACA 
GAACTTCCAG AAATGGGGCT TGTAGTGGAT GGTGCAACCT GTGGCCCTGG CAAATATTGT 
AAAGCTCAAA GATGTGTTGC TCATCCAACT TTGAATTTTA ATTGCAACAT TAGTTCGTGT 
AACTTCAGAG GGGTGTGCAA CAACAAAGGC AACTGTCACT GTGTTCGAGG ATGGCAGCCA 
CCACATTGTT TACAAATAGG AAAAGGTGGT AGTACAAATA GTGGCCCTCC ACCTACCACT 
CAGAAAAAAC ATCAAGCTGA AATACATGTG AGTGCCAACA GGCTAATAGT CATTTTAAGT 
ATTCGCATGA TTCTTATCTT GGCTTCGATT CTTTTGGGTG CAGTTTTCAA AGCAATATTT 
GTTTCAGAAA CTACAGAAGA GGAGCAACAT TCTGCTGTTA ACAGACAGTT GACTTCATAC 
CAAACTATTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033750.1
CDS	195..2486
Translation	MAPFLRPSTWTLALLRGALWLSVLWALLSPACCSRSPPKWRFSTSEIVIPRKVPQRMGKSDMSGHITYSMRFRGQRHVVHMKLKKNMIPQNFPVYTSNDQGAQQKDYPFVPRDCYFYSFLEGVPGSQAILDTCTGGLKGMIQVDDFTYEIKPLASSSKFEHVISLLVVDERSRESKKCRNDEIMAKAGDLSEETKLAGSPRAAPVYLWRYHLKSVGIHYTVTHDLFKQTGSNSSTSVELILIMNSISDSIYKISGLIVYARGVWIWNTKNLHTVPGENPHLDPWSVMAGFGVWKSKELHDLYATTAILLASRPKNTDYGSFQNGLCNPNWGVLFTYVGKNHLFLAGSFLAHAVGHLLDVSHDTPGCVCFRRSSCLMDEFPTLHDMISNCSHNELHRRIHDWDPCLSLELKTAKEVNMYEVPRCGNKRVEASEKCDCGSVKDCTTDKCCEVNCEFTQGSSCAAGGCCLSCKFAPTGTICRDKNGICDLPEYCSGASEHCPGNFYIMDGTPCSPLAVCIAGNCSDRHLQCQALFGYQVKDGSPACYNELNVKGDRFGNCGIRIIRGGSQPVPCQKEDVFCGMIHCDGVSHIPGGGEHTTFYHLKVQDVKEEQCFGYDAHHGTELPEMGLVVDGATCGPGKYCKAQRCVAHPTLNFNCNISSCNFRGVCNNKGNCHCVRGWQPPHCLQIGKGGSTNSGPPPTTQKKHQAEIHVSANRLIVILSIRMILILASILLGAVFKAIFVSETTEEEQHSAVNRQLTSYQTI

Target ORF information:

RefSeq Version	NM_009620.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus a disintegrin and metallopeptidase domain 4 (Adam4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009620.2

ORF Insert Sequence:

ATGGCTCCCT TCCTCAGACC ATCTACCTGG ACTTTGGCCC TCCTGAGAGG TGCTCTCTGG 
CTCTCTGTGC TCTGGGCACT GTTGTCTCCT GCCTGCTGTT CCCGTAGCCC ACCCAAATGG 
CGCTTCTCTA CCTCTGAAAT TGTCATCCCC AGGAAGGTTC CCCAGAGAAT GGGCAAAAGT 
GATATGTCTG GGCACATCAC CTATAGCATG CGCTTTAGGG GACAAAGACA TGTGGTCCAC 
ATGAAACTCA AGAAAAACAT GATTCCTCAA AATTTTCCTG TATATACCTC TAATGACCAA 
GGAGCCCAAC AGAAGGATTA CCCATTTGTT CCTCGGGATT GTTACTTCTA CAGCTTCCTG 
GAAGGAGTCC CTGGGTCCCA AGCTATACTA GATACCTGTA CTGGAGGTCT GAAAGGCATG 
ATACAGGTGG ATGACTTCAC TTATGAAATC AAACCATTGG CATCTTCTTC CAAATTTGAG 
CATGTAATTT CTCTGCTTGT GGTGGATGAA AGGTCACGTG AGTCAAAAAA GTGTAGAAAT 
GATGAGATTA TGGCAAAGGC AGGTGACCTC TCTGAAGAGA CCAAGCTGGC TGGAAGTCCC 
AGAGCAGCCC CTGTATATCT GTGGCGTTAC CATTTGAAAA GTGTAGGAAT ACACTACACG 
GTGACTCATG ACTTATTCAA ACAAACTGGG AGCAATTCCT CCACCTCAGT TGAGTTAATA 
CTGATTATGA ATAGCATTTC AGATAGCATT TATAAAATAA GTGGATTGAT TGTGTATGCA 
CGTGGTGTAT GGATTTGGAA TACGAAGAAC CTGCATACTG TCCCCGGTGA AAATCCCCAC 
CTTGATCCTT GGAGTGTTAT GGCAGGTTTT GGTGTATGGA AATCTAAAGA ATTGCACGAT 
TTGTATGCCA CTACAGCTAT TCTCCTTGCA TCAAGACCAA AAAATACAGA TTATGGAAGC 
TTTCAGAATG GATTATGTAA CCCCAACTGG GGAGTATTAT TTACATATGT AGGAAAAAAC 
CATTTATTTC TGGCTGGATC TTTCCTGGCA CATGCAGTGG GTCACCTTTT AGATGTAAGC 
CATGATACAC CAGGCTGTGT TTGTTTCAGA AGGAGCAGTT GTCTCATGGA TGAATTTCCT 
ACTCTTCATG ATATGATTAG TAATTGTTCC CATAATGAGT TACATAGGAG GATCCATGAC 
TGGGACCCTT GCTTGAGTTT AGAGCTAAAA ACAGCTAAAG AAGTAAACAT GTATGAAGTT 
CCTCGTTGTG GAAATAAGAG AGTGGAGGCC AGTGAGAAAT GTGACTGTGG TTCTGTGAAA 
GACTGTACCA CTGATAAGTG TTGTGAAGTC AATTGTGAGT TTACTCAGGG TAGCTCTTGT 
GCTGCAGGAG GTTGCTGTCT ATCTTGTAAG TTTGCACCCA CTGGAACAAT ATGCAGAGAC 
AAAAATGGTA TTTGTGATCT TCCAGAGTAC TGTAGTGGAG CCTCAGAGCA TTGCCCAGGA 
AATTTTTACA TCATGGATGG AACTCCTTGT TCTCCACTGG CAGTCTGCAT AGCAGGAAAC 
TGTAGTGACC GTCATTTGCA GTGTCAAGCT CTTTTTGGAT ACCAAGTAAA GGATGGTTCA 
CCAGCATGCT ATAATGAATT AAATGTCAAA GGTGACCGAT TTGGAAACTG TGGCATTAGA 
ATCATACGTG GAGGAAGCCA ACCTGTCCCA TGTCAAAAGG AGGATGTTTT TTGTGGAATG 
ATCCACTGTG ATGGTGTCAG TCATATTCCT GGTGGAGGTG AGCACACTAC CTTTTATCAC 
CTAAAGGTTC AAGATGTTAA AGAAGAACAG TGCTTTGGGT ATGATGCACA CCATGGGACA 
GAACTTCCAG AAATGGGGCT TGTAGTGGAT GGTGCAACCT GTGGCCCTGG CAAATATTGT 
AAAGCTCAAA GATGTGTTGC TCATCCAACT TTGAATTTTA ATTGCAACAT TAGTTCGTGT 
AACTTCAGAG GGGTGTGCAA CAACAAAGGC AACTGTCACT GTGTTCGAGG ATGGCAGCCA 
CCACATTGTT TACAAATAGG AAAAGGTGGT AGTACAAATA GTGGCCCTCC ACCTACCACT 
CAGAAAAAAC ATCAAGCTGA AATACATGTG AGTGCCAACA GGCTAATAGT CATTTTAAGT 
ATTCGCATGA TTCTTATCTT GGCTTCGATT CTTTTGGGTG CAGTTTTCAA AGCAATATTT 
GTTTCAGAAA CTACAGAAGA GGAGCAACAT TCTGCTGTTA ACAGACAGTT GACTTCATAC 
CAAACTATTT GA