Ankrd1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ankrd1
Entrez Gene ID	107765
Full Name	ankyrin repeat domain 1 (cardiac muscle)
Synonyms	Alrp,CARP,Crap,MARP1
General protein information	Preferred Names ankyrin repeat domain 1 (cardiac muscle) Names ankyrin repeat domain-containing protein 1 ankyrin-like repeat protein cardiac ankyrin repeat protein cardiac responsive adriamycin protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 19 Map Location: 19\|19 C2

mRNA and Protein(s)

mRNA	Protein	Name
NM_013468.3	NP_038496.2	ankyrin repeat domain-containing protein 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ANKRD1	XP_001144141.1
	ANKRD1	XP_001087855.1
Bos taurus (cattle)	ANKRD1	NP_001029550.1
Rattus norvegicus (Norway rat)	Ankrd1	NP_037352.1
Danio rerio (zebrafish)	ankrd1a	XP_001920092.1
Xenopus tropicalis (tropical clawed frog)	ankrd1	NP_001025607.1
Homo sapiens (human)	ANKRD1	NP_055206.2
Mus musculus (house mouse)	Ankrd1	NP_038496.2
Gallus gallus (chicken)	ANKRD1	NP_989736.1
Canis lupus familiaris (dog)	ANKRD1	XP_005637588.1

Gene Ontology
Bibliography

Related articles in PubMed

YAP/TAZ and Hedgehog Coordinate Growth and Patterning in Gastrointestinal Mesenchyme.
Cotton JL, Li Q, Ma L, Park JS, Wang J, Ou J, Zhu LJ, Ip YT, Johnson RL, Mao J
Developmental cell43(1)35-47.e4(2017 10)

Elastic force restricts growth of the murine utricle.
Gnedeva K, Jacobo A, Salvi JD, Petelski AA, Hudspeth AJ
eLife6(2017 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The results suggest that CARP can protect against hypoxia-reperfusion induced cardiomyocyte apoptosis, possibly through increasing anti-apoptosis Bcl2 gene expression.
Title: Cardiac ankyrin repeat protein attenuates cardiomyocyte apoptosis by upregulation of Bcl-2 expression.

ANKRD1 modulates inflammatory responses in myoblasts through feedback inhibition of NF-kappaB signaling activity.
Title: ANKRD1 modulates inflammatory responses in C2C12 myoblasts through feedback inhibition of NF-?B signaling activity.

Overexpression of Ankrd1 exacerbates pathological cardiac dysfunction through enhancement of cardiomyocyte apoptosis mediated by the up-regulation of p53.
Title: Overexpression of ankyrin repeat domain 1 enhances cardiomyocyte apoptosis by promoting p53 activation and mitochondrial dysfunction in rodents.

ANKRD1 is important for the proper interaction of fibroblasts with a compliant collagenous matrix both in vitro and in vivo
Title: Global deletion of Ankrd1 results in a wound-healing phenotype associated with dermal fibroblast dysfunction.

Overexpression of Ankrd1 exacerbates pathological cardiac remodeling through the enhancement of cytosolic translocation of CARP and up-regulation of calcineurin.
Title: Cytosolic CARP promotes angiotensin II- or pressure overload-induced cardiomyocyte hypertrophy through calcineurin accumulation.

The following Ankrd1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ankrd1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu23072	NM_013468.3 Latest version!	Mus musculus ankyrin repeat domain 1 (cardiac muscle) (Ankrd1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ankrd1 ( NM_013468.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_038496.2 Mus musculus ankyrin repeat domain 1 (cardiac muscle) (Ankrd1), mRNA.

Price & Availability↑

CloneID	OMu23072
Clone ID Related Accession (Same CDS sequence)	NM_013468.3
Accession Version	NM_013468.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 960bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-03
Organism	Mus musculus(house mouse)
Product	ankyrin repeat domain-containing protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC119234.10. On Mar 21, 2007 this sequence version replaced NM_013468.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC037138.1, AK009959.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849390, SAMN01164142 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGGTAC TGAGAGTAGA GGAGCTGGTA ACAGGCAAAA AGAACAGCAA TGGGGCCGCA 
GGGGAATTCC TTCCTGGGGA GTTCAGAAAT GGAGAATATG AAGCTGCTGT TGCTTTGGAG 
AAGCAAGAGG ACCTGAAGAC ACTTCCGGCC AACAGCGTGA AGCAGGGGGA GGAACAACGG 
AAAAGCGAGA AACTGCGAGA GGCAGAGCTC AAAAAGAAAA AACTAGAACA AAGATCAAAG 
CTTGAAAACT TAGAAGACCT TGAAATAATT GTTCAACTGA AGAAAAGGAA AAAATACAAG 
AAAACCAAAG TTCCAGTTGT GAAGGAGCCA GAACCTGAAA TTATGACTGA ACCTGTGGAT 
GTGCCGAGGT TTCTGAAAGC TGCGCTGGAG AACAAACTGC CAGTTGTAGA GAAATTCCTG 
TCAGACAAGA ACAGCCCCGA CGTCTGCGAT GAGTATAAAC GGACGGCACT CCACCGAGCA 
TGCTTAGAAG GACACTTGGC GATCGTGGAG AAGTTAATGG AGGCTGGAGC CCAGATTGAA 
TTCCGAGATA TGCTTGAATC CACAGCCATC CACTGGGCAT GTCGTGGAGG AAACGCAGAT 
GTCCTGAAAC TGTTGCTGAA CAAAGGAGCC AAAATCAGTG CCAGAGACAA GCTTCTCAGC 
ACAGCGCTGC ATGTGGCGGT GAGGACTGGT CATTACGAGT GCGCTGAGCA CCTCATCGCC 
TGCGAGGCTG ATCTCAATGC CAAGGACAGA GAAGGAGACA CCCCACTGCA TGATGCTGTG 
AGGCTGAACC GCTATAAGAT GATTCGACTC TTGATGACCT TCGGTGCGGA CCTCAAGGTC 
AAGAACTGTG CTGGGAAGAC CCCCATGGAT CTGGTGTTGC ACTGGCAGAG TGGAACCAAA 
GCAATATTCG ACAGCCTCAA GGAGAATGCC TACAAGAACT CTCGCATAGC TACATTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038496.2
CDS	64..1023
Translation	MMVLRVEELVTGKKNSNGAAGEFLPGEFRNGEYEAAVALEKQEDLKTLPANSVKQGEEQRKSEKLREAELKKKKLEQRSKLENLEDLEIIVQLKKRKKYKKTKVPVVKEPEPEIMTEPVDVPRFLKAALENKLPVVEKFLSDKNSPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWACRGGNADVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLLMTFGADLKVKNCAGKTPMDLVLHWQSGTKAIFDSLKENAYKNSRIATF

Target ORF information:

RefSeq Version	NM_013468.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ankyrin repeat domain 1 (cardiac muscle) (Ankrd1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013468.3

ORF Insert Sequence:

ATGATGGTAC TGAGAGTAGA GGAGCTGGTA ACAGGCAAAA AGAACAGCAA TGGGGCCGCA 
GGGGAATTCC TTCCTGGGGA GTTCAGAAAT GGAGAATATG AAGCTGCTGT TGCTTTGGAG 
AAGCAAGAGG ACCTGAAGAC ACTTCCGGCC AACAGCGTGA AGCAGGGGGA GGAACAACGG 
AAAAGCGAGA AACTGCGAGA GGCAGAGCTC AAAAAGAAAA AACTAGAACA AAGATCAAAG 
CTTGAAAACT TAGAAGACCT TGAAATAATT GTTCAACTGA AGAAAAGGAA AAAATACAAG 
AAAACCAAAG TTCCAGTTGT GAAGGAGCCA GAACCTGAAA TTATGACTGA ACCTGTGGAT 
GTGCCGAGGT TTCTGAAAGC TGCGCTGGAG AACAAACTGC CAGTTGTAGA GAAATTCCTG 
TCAGACAAGA ACAGCCCCGA CGTCTGCGAT GAGTATAAAC GGACGGCACT CCACCGAGCA 
TGCTTAGAAG GACACTTGGC GATCGTGGAG AAGTTAATGG AGGCTGGAGC CCAGATTGAA 
TTCCGAGATA TGCTTGAATC CACAGCCATC CACTGGGCAT GTCGTGGAGG AAACGCAGAT 
GTCCTGAAAC TGTTGCTGAA CAAAGGAGCC AAAATCAGTG CCAGAGACAA GCTTCTCAGC 
ACAGCGCTGC ATGTGGCGGT GAGGACTGGT CATTACGAGT GCGCTGAGCA CCTCATCGCC 
TGCGAGGCTG ATCTCAATGC CAAGGACAGA GAAGGAGACA CCCCACTGCA TGATGCTGTG 
AGGCTGAACC GCTATAAGAT GATTCGACTC TTGATGACCT TCGGTGCGGA CCTCAAGGTC 
AAGAACTGTG CTGGGAAGAC CCCCATGGAT CTGGTGTTGC ACTGGCAGAG TGGAACCAAA 
GCAATATTCG ACAGCCTCAA GGAGAATGCC TACAAGAACT CTCGCATAGC TACATTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

YAP/TAZ and Hedgehog Coordinate Growth and Patterning in Gastrointestinal Mesenchyme.
Developmental cell43(1)35-47.e4(2017 10)
Cotton JL,Li Q,Ma L,Park JS,Wang J,Ou J,Zhu LJ,Ip YT,Johnson RL,Mao J

Elastic force restricts growth of the murine utricle.
eLife6(2017 Jul)
Gnedeva K,Jacobo A,Salvi JD,Petelski AA,Hudspeth AJ

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Ankrd1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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