Arl2bp cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Arl2bp
Entrez Gene ID	107566
Full Name	ADP-ribosylation factor-like 2 binding protein
Synonyms	1700010P10Rik,1700027H16Rik,6330544B05Rik,AI482273,AI849834,BART,Bart1
General protein information	Preferred Names ADP-ribosylation factor-like 2 binding protein Names ADP-ribosylation factor-like protein 2-binding protein ADP-ribosylation-like 2 binding protein ARF-like 2-binding protein binder of ARF2 protein 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8\|8 C5

mRNA and Protein(s)

mRNA	Protein	Name
NM_024269.4	NP_077231.1	ADP-ribosylation factor-like protein 2-binding protein isoform 2
NM_024191.2	NP_077153.1	ADP-ribosylation factor-like protein 2-binding protein isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	ARL2BP	NP_036238.1
	ARL2BP	XP_001097110.1
Mus musculus (house mouse)	Arl2bp	NP_077153.1
Bos taurus (cattle)	ARL2BP	NP_001069742.2
Rattus norvegicus (Norway rat)	Arl2bp	NP_001020077.1
Pan troglodytes (chimpanzee)	ARL2BP	NP_001233387.1
Canis lupus familiaris (dog)	ARL2BP	XP_853982.1
Gallus gallus (chicken)	ARL2BP	NP_001007971.1
Danio rerio (zebrafish)	arl2bp	NP_957295.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012967	XP_003436484.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012917	XP_306324.3
Xenopus tropicalis (tropical clawed frog)	arl2bp	NP_001017020.1

Gene Ontology
Bibliography

Related articles in PubMed

Mutations in ARL2BP, encoding ADP-ribosylation-factor-like 2 binding protein, cause autosomal-recessive retinitis pigmentosa.
Davidson AE, Schwarz N, Zelinger L, Stern-Schneider G, Shoemark A, Spitzbarth B, Gross M, Laxer U, Sosna J, Sergouniotis PI, Waseem NH, Wilson R, Kahn RA, Plagnol V, Wolfrum U, Banin E, Hardcastle AJ, Cheetham ME, Sharon D, Webster AR
American journal of human genetics93(2)321-9(2013 Aug)

In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype.
Gineste C, De Winter JM, Kohl C, Witt CC, Giannesini B, Brohm K, Le Fur Y, Gretz N, Vilmen C, Pecchi E, Jubeau M, Cozzone PJ, Stienen GJ, Granzier H, Labeit S, Ottenheijm CA, Bendahan D, Gondin J
Neuromuscular disorders : NMD23(4)357-69(2013 Apr)

BART is essential for nuclear retention of STAT3.
Muromoto R, Sekine Y, Imoto S, Ikeda O, Okayama T, Sato N, Matsuda T
International immunology20(3)395-403(2008 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

BART is essential for the transcriptional activity and nuclear retention of STAT3
Title: BART is essential for nuclear retention of STAT3.

The following Arl2bp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Arl2bp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu07104	NM_024269.4 Latest version!	Mus musculus ADP-ribosylation factor-like 2 binding protein (Arl2bp), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu01326	NM_024191.2 Latest version!	Mus musculus ADP-ribosylation factor-like 2 binding protein (Arl2bp), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Arl2bp ( NM_024269.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_077231.1 Mus musculus ADP-ribosylation factor-like 2 binding protein (Arl2bp), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu07104
Clone ID Related Accession (Same CDS sequence)	NM_024269.4
Accession Version	NM_024269.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 459bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-26
Organism	Mus musculus(house mouse)
Product	ADP-ribosylation factor-like protein 2-binding protein isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC123826.4 and AK006418.1. On Oct 26, 2013 this sequence version replaced NM_024269.3. Transcript Variant: This variant (2) contains an alternate exon in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at an alternate start codon compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: CN831942.1, AK006418.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGCGCTCCT CCGCCTCTGA TGCAGAATTT GATGCTGTGG TTGGATGTTT AGAGGACATT 
ATTATGGATG ATGAGTTCCA GTTATTGCAG AGAAACTTCA TGGACAAGTA CTACCAGGAA 
TTTGAAGACA CAGAAGAGAA TAAACTCACC TATACACCCA TTTTTAATGA ATATATCTCC 
CTGGTAGAGA AGTACATTGA AGAGCAGTTG CTGGAGCGTA TCCCAGGCTT CAACATGGCG 
GCCTTCACAA CCACGCTGCA GCACCACAAA GATGAGGTGG CTGGCGACAT CTTTGACATG 
CTGCTCACAT TCACGGATTT TCTGGCTTTC AAGGAGATGT TCCTGGACTA CAGAGCAGAA 
AAGGAAGGCC GAGGACTGGA CTTAAGCAGC GGCTTGGTTG TGACTTCTCT GTGTAAGTCA 
TCTTCTACGC CAGCTTCCCA GAACAACCTG CGGCACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_077231.1
CDS	136..594
Translation	MRSSASDAEFDAVVGCLEDIIMDDEFQLLQRNFMDKYYQEFEDTEENKLTYTPIFNEYISLVEKYIEEQLLERIPGFNMAAFTTTLQHHKDEVAGDIFDMLLTFTDFLAFKEMFLDYRAEKEGRGLDLSSGLVVTSLCKSSSTPASQNNLRH

Target ORF information:

RefSeq Version	NM_024269.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus ADP-ribosylation factor-like 2 binding protein (Arl2bp), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024269.4

ORF Insert Sequence:

ATGCGCTCCT CCGCCTCTGA TGCAGAATTT GATGCTGTGG TTGGATGTTT AGAGGACATT 
ATTATGGATG ATGAGTTCCA GTTATTGCAG AGAAACTTCA TGGACAAGTA CTACCAGGAA 
TTTGAAGACA CAGAAGAGAA TAAACTCACC TATACACCCA TTTTTAATGA ATATATCTCC 
CTGGTAGAGA AGTACATTGA AGAGCAGTTG CTGGAGCGTA TCCCAGGCTT CAACATGGCG 
GCCTTCACAA CCACGCTGCA GCACCACAAA GATGAGGTGG CTGGCGACAT CTTTGACATG 
CTGCTCACAT TCACGGATTT TCTGGCTTTC AAGGAGATGT TCCTGGACTA CAGAGCAGAA 
AAGGAAGGCC GAGGACTGGA CTTAAGCAGC GGCTTGGTTG TGACTTCTCT GTGTAAGTCA 
TCTTCTACGC CAGCTTCCCA GAACAACCTG CGGCACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Arl2bp ( NM_024191.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_077153.1 Mus musculus ADP-ribosylation factor-like 2 binding protein (Arl2bp), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu01326
Clone ID Related Accession (Same CDS sequence)	NM_024191.2
Accession Version	NM_024191.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 492bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-26
Organism	Mus musculus(house mouse)
Product	ADP-ribosylation factor-like protein 2-binding protein isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY159929.1, AK018229.1 and AC123826.4. On Oct 26, 2013 this sequence version replaced NM_024191.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK155242.1, BC024708.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGACGCCC TAGAAGAAGA GAGCTTCGCG CTGTCCTTCT CCTCCGCCTC TGATGCAGAA 
TTTGATGCTG TGGTTGGATG TTTAGAGGAC ATTATTATGG ATGATGAGTT CCAGTTATTG 
CAGAGAAACT TCATGGACAA GTACTACCAG GAATTTGAAG ACACAGAAGA GAATAAACTC 
ACCTATACAC CCATTTTTAA TGAATATATC TCCCTGGTAG AGAAGTACAT TGAAGAGCAG 
TTGCTGGAGC GTATCCCAGG CTTCAACATG GCGGCCTTCA CAACCACGCT GCAGCACCAC 
AAAGATGAGG TGGCTGGCGA CATCTTTGAC ATGCTGCTCA CATTCACGGA TTTTCTGGCT 
TTCAAGGAGA TGTTCCTGGA CTACAGAGCA GAAAAGGAAG GCCGAGGACT GGACTTAAGC 
AGCGGCTTGG TTGTGACTTC TCTGTGTAAG TCATCTTCTA CGCCAGCTTC CCAGAACAAC 
CTGCGGCACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_077153.1
CDS	265..756
Translation	MDALEEESFALSFSSASDAEFDAVVGCLEDIIMDDEFQLLQRNFMDKYYQEFEDTEENKLTYTPIFNEYISLVEKYIEEQLLERIPGFNMAAFTTTLQHHKDEVAGDIFDMLLTFTDFLAFKEMFLDYRAEKEGRGLDLSSGLVVTSLCKSSSTPASQNNLRH

Target ORF information:

RefSeq Version	NM_024191.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ADP-ribosylation factor-like 2 binding protein (Arl2bp), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024191.2

ORF Insert Sequence:

ATGGACGCCC TAGAAGAAGA GAGCTTCGCG CTGTCCTTCT CCTCCGCCTC TGATGCAGAA 
TTTGATGCTG TGGTTGGATG TTTAGAGGAC ATTATTATGG ATGATGAGTT CCAGTTATTG 
CAGAGAAACT TCATGGACAA GTACTACCAG GAATTTGAAG ACACAGAAGA GAATAAACTC 
ACCTATACAC CCATTTTTAA TGAATATATC TCCCTGGTAG AGAAGTACAT TGAAGAGCAG 
TTGCTGGAGC GTATCCCAGG CTTCAACATG GCGGCCTTCA CAACCACGCT GCAGCACCAC 
AAAGATGAGG TGGCTGGCGA CATCTTTGAC ATGCTGCTCA CATTCACGGA TTTTCTGGCT 
TTCAAGGAGA TGTTCCTGGA CTACAGAGCA GAAAAGGAAG GCCGAGGACT GGACTTAAGC 
AGCGGCTTGG TTGTGACTTC TCTGTGTAAG TCATCTTCTA CGCCAGCTTC CCAGAACAAC 
CTGCGGCACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mutations in ARL2BP, encoding ADP-ribosylation-factor-like 2 binding protein, cause autosomal-recessive retinitis pigmentosa.
American journal of human genetics93(2)321-9(2013 Aug)
Davidson AE,Schwarz N,Zelinger L,Stern-Schneider G,Shoemark A,Spitzbarth B,Gross M,Laxer U,Sosna J,Sergouniotis PI,Waseem NH,Wilson R,Kahn RA,Plagnol V,Wolfrum U,Banin E,Hardcastle AJ,Cheetham ME,Sharon D,Webster AR

In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype.
Neuromuscular disorders : NMD23(4)357-69(2013 Apr)
Gineste C,De Winter JM,Kohl C,Witt CC,Giannesini B,Brohm K,Le Fur Y,Gretz N,Vilmen C,Pecchi E,Jubeau M,Cozzone PJ,Stienen GJ,Granzier H,Labeit S,Ottenheijm CA,Bendahan D,Gondin J

BART is essential for nuclear retention of STAT3.
International immunology20(3)395-403(2008 Mar)
Muromoto R,Sekine Y,Imoto S,Ikeda O,Okayama T,Sato N,Matsuda T

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Arl2bp cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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