Epop cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Epop
Entrez Gene ID	103551
Full Name	elongin BC and polycomb repressive complex 2 associated protein
Synonyms	AA409164,AI413509,AW539173,E13,E130012A19Rik,esPRC2p48
General protein information	Preferred Names elongin BC and polycomb repressive complex 2 associated protein Names elongin BC and Polycomb repressive complex 2-associated protein ES cell-specific PRC2 subunit p48 elongin and polycomb associated protein embryonic stem cell-specific PRC2 subunit p48 uncharacterized protein C17orf96 homolog
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11\|11 D

mRNA and Protein(s)

mRNA	Protein	Name
NM_175332.3	NP_780541.2	elongin BC and Polycomb repressive complex 2-associated protein

Pathways from BioSystems

Homologies

	C16H17orf96	XP_001083198.1
Rattus norvegicus (Norway rat)	LOC691153	NP_001103097.1
Pan troglodytes (chimpanzee)	C17H17orf96	XP_003315550.1
Canis lupus familiaris (dog)	C9H17orf96	XP_850731.2
Mus musculus (house mouse)	E130012A19Rik	NP_780541.2
Homo sapiens (human)	C17orf96	NP_001124149.1
Bos taurus (cattle)	C19H17orf96	XP_002695995.1

Gene Ontology
Bibliography

Related articles in PubMed

EPOP Functionally Links Elongin and Polycomb in Pluripotent Stem Cells.
Beringer M, Pisano P, Di Carlo V, Blanco E, Chammas P, Viz?n P, Guti?rrez A, Aranda S, Payer B, Wierer M, Di Croce L
Molecular cell64(4)645-658(2016 Nov)

EPOP Interacts with Elongin BC and USP7 to Modulate the Chromatin Landscape.
Liefke R, Karwacki-Neisius V, Shi Y
Molecular cell64(4)659-672(2016 Nov)

Reverse engineering a mouse embryonic stem cell-specific transcriptional network reveals a new modulator of neuronal differentiation.
De Cegli R, Iacobacci S, Flore G, Gambardella G, Mao L, Cutillo L, Lauria M, Klose J, Illingworth E, Banfi S, di Bernardo D
Nucleic acids research41(2)711-26(2013 Jan)

Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal.
Hunkapiller J, Shen Y, Diaz A, Cagney G, McCleary D, Ramalho-Santos M, Krogan N, Ren B, Song JS, Reiter JF
PLoS genetics8(3)e1002576(2012)

PRC2 complexes with JARID2, MTF2, and esPRC2p48 in ES cells to modulate ES cell pluripotency and somatic cell reprogramming.
Zhang Z, Jones A, Sun CW, Li C, Chang CW, Joo HY, Dai Q, Mysliwiec MR, Wu LC, Guo Y, Yang W, Liu K, Pawlik KM, Erdjument-Bromage H, Tempst P, Lee Y, Min J, Townes TM, Wang H
Stem cells (Dayton, Ohio)29(2)229-40(2011 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

EPOP (E130012A19Rik) functionally links elongin B, elongin C, and polycomb in pluripotent stem cells.
Title: EPOP Functionally Links Elongin and Polycomb in Pluripotent Stem Cells.

EPOP (E130012A19Rik) interacts with elongin B, elongin C, and USP7 to modulate the chromatin landscape.
Title: EPOP Interacts with Elongin BC and USP7 to Modulate the Chromatin Landscape.

Results demonstrated that E130012A19Rik (E13), is a protein-coding gene implicated in regulating the commitment towards the different neuronal subtypes and glia cells.
Title: Reverse engineering a mouse embryonic stem cell-specific transcriptional network reveals a new modulator of neuronal differentiation.

these studies identify JARID2, MTF2, and esPRC2p48 as important regulatory subunits of PRC2 in ES cells and reveal critical functions of these subunits.
Title: PRC2 complexes with JARID2, MTF2, and esPRC2p48 in ES cells to modulate ES cell pluripotency and somatic cell reprogramming.

The following Epop gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Epop cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu14373	NM_175332.3 Latest version!	Mus musculus elongin BC and polycomb repressive complex 2 associated protein (Epop), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Epop ( NM_175332.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_780541.2 Mus musculus elongin BC and polycomb repressive complex 2 associated protein (Epop), mRNA.

Price & Availability↑

CloneID	OMu14373
Clone ID Related Accession (Same CDS sequence)	NM_175332.3
Accession Version	NM_175332.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1110bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Mus musculus(house mouse)
Product	elongin BC and Polycomb repressive complex 2-associated protein
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC055770.1. On Aug 5, 2006 this sequence version replaced NM_175332.2. ##Evidence-Data-START## Transcript is intronless :: BC055770.1 [ECO:0000345] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGACTC TGTGTCCTCC TCCCCGCCTG GCAGTGCCCG CTTCCCCGCG GGGGTCTCCC 
TGCTCGCCTA CGCCCCTGAA GCCGCGTCGG GGGACCCCAG AGTTCTCCCC ACTGTGCCTG 
CGTGCCCTCG CCTTCTGCGC CCTTGCCAAA CCCCGGCCGT CCTCCCTGGG CCTGGGGCCT 
GGAGAGCTGG CGCCGCGGAC CCCGGTGCTG CTGGGCCCCC CGGCCTCGCC ATGCACAGGA 
GGCTGGGCCG CGGACGGCCT GAAGCACCTC GGGGGACAGG CCGGGCGGCC GAGCGACGTG 
AGCTCCCCGG CCCGCGAGGA TGCAGACGTC GCGGTGTGCC CAGGCGGTGG AGAGGAGGAA 
GAGGGCGGAG GCGGCTTCCC GCACTTCGGC GCTGGTTCCT GCGCACCTCC GGGCCGCTGC 
CCTGCTCCCC TGCGTCCTCA GGACTCTCCG ACCAACCCCG CCTGGTCCCC GCCCAGGCCA 
GCCCGGGGTC TTGATGCAGC TAGCAGTCCG CCCCTTGAGC CCGGCTCCCC GCCTCCGTCG 
CCACCTGCGG GCCTCTCCCC GGAGCCTGCG CCTTCCGAGC AGCCTGTGCC GGCCTCCGAG 
GCTCCAGGGG GTGGAGACCC TGCGCCGACC GCGCCTGAGG CACCCGCGCT CAGCCCCTCG 
ACGGCAGACG CAGCACCGGA CCCGCCCCGC GATCTCCGCC AGGAACATTT CAACCGCCTG 
ATCCGCCGCT CGAAACTTTG GTGTTACGCG AAGGGGTTCG CCCTGGACAC TCCAAGTTTG 
CGCCGAGGGC CCGAACGGCC CGCGGCCAAA GCCCGTGGAG CAGCCAAGAA ACGACGGCGG 
CCAGCGCCGC CCCCGCCCAG TGTGCAGCCA CGGCGGCCCG TCCCGACGCT TCCTACATCG 
AGCACCTTCA GCCTCCTTGA CTGCTTCCCC TGTCCCCCAG CTCTGGTGGT GGAAGAGAAC 
GGAGACCTAG GGCCGGCTTC CTCGCTTCGC CTCCAGGGAG ACGCCAAGCC GCCGCCTGCC 
CACCCGCTGT GGAAGTGGCA GATGGGAGGA CCCGCTGTCC CTGAGCCCCC GGGTCTCAAA 
TCCTGGTGGG TCAACTTGGA AGAACTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_780541.2
CDS	436..1545
Translation	METLCPPPRLAVPASPRGSPCSPTPLKPRRGTPEFSPLCLRALAFCALAKPRPSSLGLGPGELAPRTPVLLGPPASPCTGGWAADGLKHLGGQAGRPSDVSSPAREDADVAVCPGGGEEEEGGGGFPHFGAGSCAPPGRCPAPLRPQDSPTNPAWSPPRPARGLDAASSPPLEPGSPPPSPPAGLSPEPAPSEQPVPASEAPGGGDPAPTAPEAPALSPSTADAAPDPPRDLRQEHFNRLIRRSKLWCYAKGFALDTPSLRRGPERPAAKARGAAKKRRRPAPPPPSVQPRRPVPTLPTSSTFSLLDCFPCPPALVVEENGDLGPASSLRLQGDAKPPPAHPLWKWQMGGPAVPEPPGLKSWWVNLEEL

Target ORF information:

RefSeq Version	NM_175332.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus elongin BC and polycomb repressive complex 2 associated protein (Epop), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175332.3

ORF Insert Sequence:

ATGGAGACTC TGTGTCCTCC TCCCCGCCTG GCAGTGCCCG CTTCCCCGCG GGGGTCTCCC 
TGCTCGCCTA CGCCCCTGAA GCCGCGTCGG GGGACCCCAG AGTTCTCCCC ACTGTGCCTG 
CGTGCCCTCG CCTTCTGCGC CCTTGCCAAA CCCCGGCCGT CCTCCCTGGG CCTGGGGCCT 
GGAGAGCTGG CGCCGCGGAC CCCGGTGCTG CTGGGCCCCC CGGCCTCGCC ATGCACAGGA 
GGCTGGGCCG CGGACGGCCT GAAGCACCTC GGGGGACAGG CCGGGCGGCC GAGCGACGTG 
AGCTCCCCGG CCCGCGAGGA TGCAGACGTC GCGGTGTGCC CAGGCGGTGG AGAGGAGGAA 
GAGGGCGGAG GCGGCTTCCC GCACTTCGGC GCTGGTTCCT GCGCACCTCC GGGCCGCTGC 
CCTGCTCCCC TGCGTCCTCA GGACTCTCCG ACCAACCCCG CCTGGTCCCC GCCCAGGCCA 
GCCCGGGGTC TTGATGCAGC TAGCAGTCCG CCCCTTGAGC CCGGCTCCCC GCCTCCGTCG 
CCACCTGCGG GCCTCTCCCC GGAGCCTGCG CCTTCCGAGC AGCCTGTGCC GGCCTCCGAG 
GCTCCAGGGG GTGGAGACCC TGCGCCGACC GCGCCTGAGG CACCCGCGCT CAGCCCCTCG 
ACGGCAGACG CAGCACCGGA CCCGCCCCGC GATCTCCGCC AGGAACATTT CAACCGCCTG 
ATCCGCCGCT CGAAACTTTG GTGTTACGCG AAGGGGTTCG CCCTGGACAC TCCAAGTTTG 
CGCCGAGGGC CCGAACGGCC CGCGGCCAAA GCCCGTGGAG CAGCCAAGAA ACGACGGCGG 
CCAGCGCCGC CCCCGCCCAG TGTGCAGCCA CGGCGGCCCG TCCCGACGCT TCCTACATCG 
AGCACCTTCA GCCTCCTTGA CTGCTTCCCC TGTCCCCCAG CTCTGGTGGT GGAAGAGAAC 
GGAGACCTAG GGCCGGCTTC CTCGCTTCGC CTCCAGGGAG ACGCCAAGCC GCCGCCTGCC 
CACCCGCTGT GGAAGTGGCA GATGGGAGGA CCCGCTGTCC CTGAGCCCCC GGGTCTCAAA 
TCCTGGTGGG TCAACTTGGA AGAACTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

EPOP Functionally Links Elongin and Polycomb in Pluripotent Stem Cells.
Molecular cell64(4)645-658(2016 Nov)
Beringer M,Pisano P,Di Carlo V,Blanco E,Chammas P,Viz?n P,Guti?rrez A,Aranda S,Payer B,Wierer M,Di Croce L

EPOP Interacts with Elongin BC and USP7 to Modulate the Chromatin Landscape.
Molecular cell64(4)659-672(2016 Nov)
Liefke R,Karwacki-Neisius V,Shi Y

Reverse engineering a mouse embryonic stem cell-specific transcriptional network reveals a new modulator of neuronal differentiation.
Nucleic acids research41(2)711-26(2013 Jan)
De Cegli R,Iacobacci S,Flore G,Gambardella G,Mao L,Cutillo L,Lauria M,Klose J,Illingworth E,Banfi S,di Bernardo D

Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal.
PLoS genetics8(3)e1002576(2012)
Hunkapiller J,Shen Y,Diaz A,Cagney G,McCleary D,Ramalho-Santos M,Krogan N,Ren B,Song JS,Reiter JF

PRC2 complexes with JARID2, MTF2, and esPRC2p48 in ES cells to modulate ES cell pluripotency and somatic cell reprogramming.
Stem cells (Dayton, Ohio)29(2)229-40(2011 Feb)
Zhang Z,Jones A,Sun CW,Li C,Chang CW,Joo HY,Dai Q,Mysliwiec MR,Wu LC,Guo Y,Yang W,Liu K,Pawlik KM,Erdjument-Bromage H,Tempst P,Lee Y,Min J,Townes TM,Wang H

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Epop cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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