Nlrp6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Nlrp6
Entrez Gene ID	101613
Full Name	NLR family, pyrin domain containing 6
Synonyms	AI504961,Avr,Nalp6,Navr,Navr/Avr,Non-AVR,Pypaf5
General protein information	Preferred Names NLR family, pyrin domain containing 6 Names NACHT, LRR and PYD domains-containing protein 6 NACHT, leucine rich repeat and PYD containing 6 NACHT/LRR/pyrin domain-containing protein 6 PYRIN-containing APAF1-like protein 5 angiotensin II/vasopressin receptor non-angiotensin-vasopressin receptor
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 F5
Summary	The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. [provided by RefSeq, Feb 2013].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006536149.4	XP_006536212.1	NACHT, LRR and PYD domains-containing protein 6 isoform X1
NM_133946.2	NP_598707.2	NACHT, LRR and PYD domains-containing protein 6
XM_006536149.3	XP_006536212.1	NACHT, LRR and PYD domains-containing protein 6 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	NLRP6	XP_540513.3
Bos taurus (cattle)	NLRP6	XP_002683779.2
Rattus norvegicus (Norway rat)	LOC100912017	XP_006230648.1
	NLRP6	NP_001107586.1
Mus musculus (house mouse)	Nlrp6	NP_598707.2
Rattus norvegicus (Norway rat)	Nlrp6	NP_599202.2
Pan troglodytes (chimpanzee)	NLRP6	XP_521701.3
Homo sapiens (human)	NLRP6	NP_001263629.1

Gene Ontology
Bibliography

Related articles in PubMed

Clostridium butyricum regulates visceral hypersensitivity of irritable bowel syndrome by inhibiting colonic mucous low grade inflammation through its action on NLRP6.
Zhao K, Yu L, Wang X, He Y, Lu B
Acta biochimica et biophysica Sinica(2018 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

this study shows that Nlrp6-dependent Inflammasomes do not shape the commensal gut microbiota composition
Title: Nlrp6- and ASC-Dependent Inflammasomes Do Not Shape the Commensal Gut Microbiota Composition.

NLRP6 is important for suppressing the development of spontaneous colitis in the Il10 (-/-) inflammatory bowel disease model and NLRP6 deficiency results in the enrichment of Akkermansia muciniphila.
Title: NLRP6 Protects Il10

this review discuss recent findings related to NLRP6 activity, while highlighting outstanding questions and future perspectives in elucidating its roles in health and disease
Title: NLRP6: A Multifaceted Innate Immune Sensor.

these data reveal a previously unappreciated role for NLRP6 in inflammatory monocytes, which are recruited after dextran sodium sulfate-induced intestinal injury to promote barrier function and limit bacteria-driven inflammation
Title: NLRP6 function in inflammatory monocytes reduces susceptibility to chemically induced intestinal injury.

Study identified a set of microbiota-modulated metabolites whose integrative activity drives NLRP6 inflammasome activation and downstream epithelial IL-18-induced anti-microbial peptide secretion, thereby providing favorable conditions for WT microbiota colonization.
Title: Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling.

The following Nlrp6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nlrp6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu17154	NM_133946.2 Latest version!	Mus musculus NLR family, pyrin domain containing 6 (Nlrp6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OMu40036	XM_006536149.4 Latest version!	Mus musculus NLR family, pyrin domain containing 6 (Nlrp6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
View Old Accession Versions >>
OMu40036	XM_006536149.3	Mus musculus NLR family, pyrin domain containing 6 (Nlrp6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nlrp6 ( NM_133946.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_598707.2 Mus musculus NLR family, pyrin domain containing 6 (Nlrp6), mRNA.

Price & Availability↑

CloneID	OMu17154
Clone ID Related Accession (Same CDS sequence)	NM_133946.2
Accession Version	NM_133946.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2610bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Mus musculus(house mouse)
Product	NACHT, LRR and PYD domains-containing protein 6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BB869957.1, FJ222825.1 and AY355343.1. On Feb 27, 2013 this sequence version replaced NM_133946.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FJ222825.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849377 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATGCCG CTGGAGCCTC CTGCTCCAGC GTGGATGCAG TGGCAAGGGA GCTGCTTATG 
GCTACACTGG AGGAGCTGAG CCAGGAGCAG CTGAAGCGCT TCCGCCACAA GCTAAGGGAT 
GCGCCCCTGG ATGGCCGCAG CATCCCGTGG GGGCGACTGG AGCGCTCAGA CGCTGTGGAC 
CTTGTCGACA AGCTCATTGA GTTCTATGAG CCAGTGCCAG CTGTAGAAAT GACCCGGCAG 
GTCCTGAAGA GGTCGGATAT TCGAGATGTG GCCTCGCGAC TTAAGCAACA GCAGCTACAG 
AAGCTCGGCC CCACCTCGGT GCTTCTCTCC GTGTCAGCGT TCAAGAAGAA GTACCGCGAG 
CACGTGCTAC GACAGCATGC TAAGGTGAAG GAGAGGAATG CTCGCTCTGT GAAGATCAAC 
AAGCGCTTCA CCAAGCTGCT CATCGCTCCG GGGACCGGCG CTGTGGAGGA CGAGCTGCTG 
GGGCCGTTGG GGGAGCCGGA GCCCGAACGC GCTCGGCGCT CGGACACGCA CACTTTTAAT 
CGGCTCTTCC GGGGAAATGA TGAAGAGAGC TCGCAGCCGC TGACCGTGGT GCTGCAGGGC 
CCGGCAGGCA TCGGCAAAAC CATGGCCGCC AAGAAAATCC TCTATGACTG GGCAGCAGGT 
AAGCTATACC ACAGCCAGGT GGACTTTGCC TTCTTCATGC CGTGCGGCGA GCTGCTGGAG 
CGGCCGGGAA AGCGCAGCTT GGCGGACCTG GTGCTGGACC AGTGCCCGGA CCGCGCTTGG 
CCAGTGAAGC GGATACTGGC GCAACCCAAT CGCCTACTGT TCATCCTGGA CGGTGCAGAC 
GAGCTGCCTA CTTTACCATC CTCAGAGGCC ACTCCCTGCA AAGACCCTTT GGAGGCTACA 
AGTGGCTTGA GAGTGCTGAG CGGGCTGCTG AGCCAGGAGC TGTTACCAGG AGCTCGCTTG 
CTAGTGACTA CACGCCATGC CGCTACAGGG AGGCTGCAGG GCAGATTGTG CTCGCCACAG 
TGCGCAGAAA TACGCGGCTT CTCAGACAAA GACAAAAAAA AGTATTTCTT CAAGTTCTTC 
CGGGACGAGA GGAAGGCAGA GCGCGCTTAC CGCTTCGTGA AAGAGAACGA GACGCTGTTT 
GCACTGTGCT TTGTGCCCTT CGTGTGCTGG ATCGTGTGCA CAGTGCTGCA GCAGCAGCTA 
GAGCTGGGCC GGGATCTCTC TCGTACCTCC AAGACCACTA CTTCTGTGTA CCTGCTCTTC 
ATCACCAGCA TGCTGAAGTC TGCAGGCACC AATGGACCCC GGGTTCAGGG AGAGCTGAGA 
ACGCTGTGTC GCCTGGCCAG GGAGGGCATC CTGGATCATC ATAAAGCACA ATTCTCAGAA 
GAGGACCTGG AGAAATTGAA GCTTCGGGGT TCCCAAGTTC AGACAATATT TCTCAACAAG 
AAAGAGATAC CAGGAGTGCT AAAAACTGAG GTCACCTACC AGTTCATTGA CCAGAGCTTC 
CAGGAGTTCT TGGCTGCATT GTCATACCTA CTAGAAGCTG AGCGAACTCC GGGGACGCCC 
GCAGGCGGTG TGCAGAAGCT CCTGAACTCT GACGCGGAGC TACGTGGTCA TCTTGCACTG 
ACCACCCGAT TCCTCTTTGG CCTGCTAAAT ACAGAGGGGC TTCGTGACAT TGGAAACCAT 
TTTGGCTGTG TGGTGCCAGA TCATGTGAAA AAGGACACCC TGCGGTGGGT ACAAGGACAG 
AGCCACCCCA AGGGGCCACC AGTAGGGGCA AAAAAGACTG CTGAGCTGGA GGACATCGAG 
GACGCAGAGG AGGAGGAGGA GGAAGAGGAG GACCTCAATT TTGGACTGGA GCTGCTGTAC 
TGCCTGTATG AGACACAGGA GGAGGATTTT GTTCGACAGG CTCTCAGCAG CCTTCCAGAG 
ATAGTACTGG AGCGAGTCAG GTTGACCCGC ATGGACCTTG AAGTTCTGAA TTACTGCGTG 
CAGTGCTGCC CAGATGGCCA GGCTCTGAGA CTGGTGAGCT GTGGGCTGGT GGCGGCAAAG 
GAGAAGAAGA AGAAGAAGAA GAGCCTGGTG AAGCGGCTGA AGGGCTCTCA AAGCACCAAG 
AAACAACCCC CAGTCTCCTT GCTGCGTCCA CTCTGTGAGA CAATGACTAC CCCGAAATGT 
CATCTGAGTG TTCTGATCTT GTCACACTGC AGACTCCCTG ATGCAGTTTG CCGAGACCTT 
TCCGAGGCCC TGAAGGTAGC TCCTGCCCTA AGGGAGTTGG GCCTCCTCCA GAGCCGGCTC 
ACCAACACAG GCCTGCGTTT ACTGTGCGAA GGCCTGGCTT GGCCCAAGTG CCAGGTGAAG 
ACACTCAGGA TGCAGCTGCC TGACCTCCAA GAGGTGATCA ATTACTTGGT CATCGTGCTC 
CAGCAGAGCC CAGTCCTGAC CACTCTGGAC CTCAGTGGCT GTCAGCTGCC TGGCGTCATT 
GTGGAACCTC TGTGTGCAGC CCTGAAGCAC CCTAAATGCT CCCTAAAGAC CCTCAGTCTG 
ACCTCTGTGG AGCTGAGTGA GAACTCACTG AGGGATCTTC AAGCTGTGAA GACATCAAAG 
CCAGATCTGT CCATCATATA TTCAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598707.2
CDS	157..2766
Translation	MDAAGASCSSVDAVARELLMATLEELSQEQLKRFRHKLRDAPLDGRSIPWGRLERSDAVDLVDKLIEFYEPVPAVEMTRQVLKRSDIRDVASRLKQQQLQKLGPTSVLLSVSAFKKKYREHVLRQHAKVKERNARSVKINKRFTKLLIAPGTGAVEDELLGPLGEPEPERARRSDTHTFNRLFRGNDEESSQPLTVVLQGPAGIGKTMAAKKILYDWAAGKLYHSQVDFAFFMPCGELLERPGKRSLADLVLDQCPDRAWPVKRILAQPNRLLFILDGADELPTLPSSEATPCKDPLEATSGLRVLSGLLSQELLPGARLLVTTRHAATGRLQGRLCSPQCAEIRGFSDKDKKKYFFKFFRDERKAERAYRFVKENETLFALCFVPFVCWIVCTVLQQQLELGRDLSRTSKTTTSVYLLFITSMLKSAGTNGPRVQGELRTLCRLAREGILDHHKAQFSEEDLEKLKLRGSQVQTIFLNKKEIPGVLKTEVTYQFIDQSFQEFLAALSYLLEAERTPGTPAGGVQKLLNSDAELRGHLALTTRFLFGLLNTEGLRDIGNHFGCVVPDHVKKDTLRWVQGQSHPKGPPVGAKKTAELEDIEDAEEEEEEEEDLNFGLELLYCLYETQEEDFVRQALSSLPEIVLERVRLTRMDLEVLNYCVQCCPDGQALRLVSCGLVAAKEKKKKKKSLVKRLKGSQSTKKQPPVSLLRPLCETMTTPKCHLSVLILSHCRLPDAVCRDLSEALKVAPALRELGLLQSRLTNTGLRLLCEGLAWPKCQVKTLRMQLPDLQEVINYLVIVLQQSPVLTTLDLSGCQLPGVIVEPLCAALKHPKCSLKTLSLTSVELSENSLRDLQAVKTSKPDLSIIYSK

Target ORF information:

RefSeq Version	NM_133946.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus NLR family, pyrin domain containing 6 (Nlrp6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133946.2

ORF Insert Sequence:

ATGGATGCCG CTGGAGCCTC CTGCTCCAGC GTGGATGCAG TGGCAAGGGA GCTGCTTATG 
GCTACACTGG AGGAGCTGAG CCAGGAGCAG CTGAAGCGCT TCCGCCACAA GCTAAGGGAT 
GCGCCCCTGG ATGGCCGCAG CATCCCGTGG GGGCGACTGG AGCGCTCAGA CGCTGTGGAC 
CTTGTCGACA AGCTCATTGA GTTCTATGAG CCAGTGCCAG CTGTAGAAAT GACCCGGCAG 
GTCCTGAAGA GGTCGGATAT TCGAGATGTG GCCTCGCGAC TTAAGCAACA GCAGCTACAG 
AAGCTCGGCC CCACCTCGGT GCTTCTCTCC GTGTCAGCGT TCAAGAAGAA GTACCGCGAG 
CACGTGCTAC GACAGCATGC TAAGGTGAAG GAGAGGAATG CTCGCTCTGT GAAGATCAAC 
AAGCGCTTCA CCAAGCTGCT CATCGCTCCG GGGACCGGCG CTGTGGAGGA CGAGCTGCTG 
GGGCCGTTGG GGGAGCCGGA GCCCGAACGC GCTCGGCGCT CGGACACGCA CACTTTTAAT 
CGGCTCTTCC GGGGAAATGA TGAAGAGAGC TCGCAGCCGC TGACCGTGGT GCTGCAGGGC 
CCGGCAGGCA TCGGCAAAAC CATGGCCGCC AAGAAAATCC TCTATGACTG GGCAGCAGGT 
AAGCTATACC ACAGCCAGGT GGACTTTGCC TTCTTCATGC CGTGCGGCGA GCTGCTGGAG 
CGGCCGGGAA AGCGCAGCTT GGCGGACCTG GTGCTGGACC AGTGCCCGGA CCGCGCTTGG 
CCAGTGAAGC GGATACTGGC GCAACCCAAT CGCCTACTGT TCATCCTGGA CGGTGCAGAC 
GAGCTGCCTA CTTTACCATC CTCAGAGGCC ACTCCCTGCA AAGACCCTTT GGAGGCTACA 
AGTGGCTTGA GAGTGCTGAG CGGGCTGCTG AGCCAGGAGC TGTTACCAGG AGCTCGCTTG 
CTAGTGACTA CACGCCATGC CGCTACAGGG AGGCTGCAGG GCAGATTGTG CTCGCCACAG 
TGCGCAGAAA TACGCGGCTT CTCAGACAAA GACAAAAAAA AGTATTTCTT CAAGTTCTTC 
CGGGACGAGA GGAAGGCAGA GCGCGCTTAC CGCTTCGTGA AAGAGAACGA GACGCTGTTT 
GCACTGTGCT TTGTGCCCTT CGTGTGCTGG ATCGTGTGCA CAGTGCTGCA GCAGCAGCTA 
GAGCTGGGCC GGGATCTCTC TCGTACCTCC AAGACCACTA CTTCTGTGTA CCTGCTCTTC 
ATCACCAGCA TGCTGAAGTC TGCAGGCACC AATGGACCCC GGGTTCAGGG AGAGCTGAGA 
ACGCTGTGTC GCCTGGCCAG GGAGGGCATC CTGGATCATC ATAAAGCACA ATTCTCAGAA 
GAGGACCTGG AGAAATTGAA GCTTCGGGGT TCCCAAGTTC AGACAATATT TCTCAACAAG 
AAAGAGATAC CAGGAGTGCT AAAAACTGAG GTCACCTACC AGTTCATTGA CCAGAGCTTC 
CAGGAGTTCT TGGCTGCATT GTCATACCTA CTAGAAGCTG AGCGAACTCC GGGGACGCCC 
GCAGGCGGTG TGCAGAAGCT CCTGAACTCT GACGCGGAGC TACGTGGTCA TCTTGCACTG 
ACCACCCGAT TCCTCTTTGG CCTGCTAAAT ACAGAGGGGC TTCGTGACAT TGGAAACCAT 
TTTGGCTGTG TGGTGCCAGA TCATGTGAAA AAGGACACCC TGCGGTGGGT ACAAGGACAG 
AGCCACCCCA AGGGGCCACC AGTAGGGGCA AAAAAGACTG CTGAGCTGGA GGACATCGAG 
GACGCAGAGG AGGAGGAGGA GGAAGAGGAG GACCTCAATT TTGGACTGGA GCTGCTGTAC 
TGCCTGTATG AGACACAGGA GGAGGATTTT GTTCGACAGG CTCTCAGCAG CCTTCCAGAG 
ATAGTACTGG AGCGAGTCAG GTTGACCCGC ATGGACCTTG AAGTTCTGAA TTACTGCGTG 
CAGTGCTGCC CAGATGGCCA GGCTCTGAGA CTGGTGAGCT GTGGGCTGGT GGCGGCAAAG 
GAGAAGAAGA AGAAGAAGAA GAGCCTGGTG AAGCGGCTGA AGGGCTCTCA AAGCACCAAG 
AAACAACCCC CAGTCTCCTT GCTGCGTCCA CTCTGTGAGA CAATGACTAC CCCGAAATGT 
CATCTGAGTG TTCTGATCTT GTCACACTGC AGACTCCCTG ATGCAGTTTG CCGAGACCTT 
TCCGAGGCCC TGAAGGTAGC TCCTGCCCTA AGGGAGTTGG GCCTCCTCCA GAGCCGGCTC 
ACCAACACAG GCCTGCGTTT ACTGTGCGAA GGCCTGGCTT GGCCCAAGTG CCAGGTGAAG 
ACACTCAGGA TGCAGCTGCC TGACCTCCAA GAGGTGATCA ATTACTTGGT CATCGTGCTC 
CAGCAGAGCC CAGTCCTGAC CACTCTGGAC CTCAGTGGCT GTCAGCTGCC TGGCGTCATT 
GTGGAACCTC TGTGTGCAGC CCTGAAGCAC CCTAAATGCT CCCTAAAGAC CCTCAGTCTG 
ACCTCTGTGG AGCTGAGTGA GAACTCACTG AGGGATCTTC AAGCTGTGAA GACATCAAAG 
CCAGATCTGT CCATCATATA TTCAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nlrp6 ( XM_006536149.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006536212.1 Mus musculus NLR family, pyrin domain containing 6 (Nlrp6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu40036
Clone ID Related Accession (Same CDS sequence)	XM_006536149.4 , XM_006536149.3
Accession Version	XM_006536149.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2700bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	NACHT, LRR and PYD domains-containing protein 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006536149.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTATTGCC CTGGGGCTCC ATGTGGAGAA TGTGCAATGT GTGACCCGGG GTGCTTTGGA 
GGTTCAGGGA CAGGTCCTAT TCAGGTCGCA TCAGTGATGA TAACCCTTCT CATCCCCAGC 
GTGGATGCAG TGGCAAGGGA GCTGCTTATG GCTACACTGG AGGAGCTGAG CCAGGAGCAG 
CTGAAGCGCT TCCGCCACAA GCTAAGGGAT GCGCCCCTGG ATGGCCGCAG CATCCCGTGG 
GGGCGACTGG AGCGCTCAGA CGCTGTGGAC CTTGTCGACA AGCTCATTGA GTTCTATGAG 
CCAGTGCCAG CTGTAGAAAT GACCCGGCAG GTCCTGAAGA GGTCGGATAT TCGAGATGTG 
GCCTCGCGAC TTAAGCAACA GCAGCTACAG AAGCTCGGCC CCACCTCGGT GCTTCTCTCC 
GTGTCAGCGT TCAAGAAGAA GTACCGCGAG CACGTGCTAC GACAGCATGC TAAGGTGAAG 
GAGAGGAATG CTCGCTCTGT GAAGATCAAC AAGCGCTTCA CCAAGCTGCT CATCGCTCCG 
GGGACCGGCG CTGTGGAGGA CGAGCTGCTG GGGCCGTTGG GGGAGCCGGA GCCCGAACGC 
GCTCGGCGCT CGGACACGCA CACTTTTAAT CGGCTCTTCC GGGGAAATGA TGAAGAGAGC 
TCGCAGCCGC TGACCGTGGT GCTGCAGGGC CCGGCAGGCA TCGGCAAAAC CATGGCCGCC 
AAGAAAATCC TCTATGACTG GGCAGCAGGT AAGCTATACC ACAGCCAGGT GGACTTTGCC 
TTCTTCATGC CGTGCGGCGA GCTGCTGGAG CGGCCGGGAA AGCGCAGCTT GGCGGACCTG 
GTGCTGGACC AGTGCCCGGA CCGCGCTTGG CCAGTGAAGC GGATACTGGC GCAACCCAAT 
CGCCTACTGT TCATCCTGGA CGGTGCAGAC GAGCTGCCTA CTTTACCATC CTCAGAGGCC 
ACTCCCTGCA AAGACCCTTT GGAGGCTACA AGTGGCTTGA GAGTGCTGAG CGGGCTGCTG 
AGCCAGGAGC TGTTACCAGG AGCTCGCTTG CTAGTGACTA CACGCCATGC CGCTACAGGG 
AGGCTGCAGG GCAGATTGTG CTCGCCACAG TGCGCAGAAA TACGCGGCTT CTCAGACAAA 
GACAAAAAAA AGTATTTCTT CAAGTTCTTC CGGGACGAGA GGAAGGCAGA GCGCGCTTAC 
CGCTTCGTGA AAGAGAACGA GACGCTGTTT GCACTGTGCT TTGTGCCCTT CGTGTGCTGG 
ATCGTGTGCA CAGTGCTGCA GCAGCAGCTA GAGCTGGGCC GGGATCTCTC TCGTACCTCC 
AAGACCACTA CTTCTGTGTA CCTGCTCTTC ATCACCAGCA TGCTGAAGTC TGCAGGCACC 
AATGGACCCC GGGTTCAGGG AGAGCTGAGA ACGCTGTGTC GCCTGGCCAG GGAGGGCATC 
CTGGATCATC ATAAAGCACA ATTCTCAGAA GAGGACCTGG AGAAATTGAA GCTTCGGGGT 
TCCCAAGTTC AGACAATATT TCTCAACAAG AAAGAGATAC CAGGAGTGCT AAAAACTGAG 
GTCACCTACC AGTTCATTGA CCAGAGCTTC CAGGAGTTCT TGGCTGCATT GTCATACCTA 
CTAGAAGCTG AGCGAACTCC GGGGACGCCC GCAGGCGGTG TGCAGAAGCT CCTGAACTCT 
GACGCGGAGC TACGTGGTCA TCTTGCACTG ACCACCCGAT TCCTCTTTGG CCTGCTAAAT 
ACAGAGGGGC TTCGTGACAT TGGAAACCAT TTTGGCTGTG TGGTGCCAGA TCATGTGAAA 
AAGGACACCC TGCGGTGGGT ACAAGGACAG AGCCACCCCA AGGGGCCACC AGTAGGGGCA 
AAAAAGACTG CTGAGCTGGA GGACATCGAG GACGCAGAGG AGGAGGAGGA GGAAGAGGAG 
GACCTCAATT TTGGACTGGA GCTGCTGTAC TGCCTGTATG AGACACAGGA GGAGGATTTT 
GTTCGACAGG CTCTCAGCAG CCTTCCAGAG ATAGTACTGG AGCGAGTCAG GTTGACCCGC 
ATGGACCTTG AAGTTCTGAA TTACTGCGTG CAGTGCTGCC CAGATGGCCA GGCTCTGAGA 
CTGGTGAGCT GTGGGCTGGT GGCGGCAAAG GAGAAGAAGA AGAAGAAGAA GAGCCTGGTG 
AAGCGGCTGA AGGGCTCTCA AAGCACCAAG AAACAACCCC CAGTCTCCTT GCTGCGTCCA 
CTCTGTGAGA CAATGACTAC CCCGAAATGT CATCTGAGTG TTCTGATCTT GTCACACTGC 
AGACTCCCTG ATGCAGTTTG CCGAGACCTT TCCGAGGCCC TGAAGGTAGC TCCTGCCCTA 
AGGGAGTTGG GCCTCCTCCA GAGCCGGCTC ACCAACACAG GCCTGCGTTT ACTGTGCGAA 
GGCCTGGCTT GGCCCAAGTG CCAGGTGAAG ACACTCAGGA TGCAGCTGCC TGACCTCCAA 
GAGGTGATCA ATTACTTGGT CATCGTGCTC CAGCAGAGCC CAGTCCTGAC CACTCTGGAC 
CTCAGTGGCT GTCAGCTGCC TGGCGTCATT GTGGAACCTC TGTGTGCAGC CCTGAAGCAC 
CCTAAATGCT CCCTAAAGAC CCTCAGTCTG ACCTCTGTGG AGCTGAGTGA GAACTCACTG 
AGGGATCTTC AAGCTGTGAA GACATCAAAG CCAGATCTGT CCATCATATA TTCAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006536212.1
CDS	16..2715
Translation	MYCPGAPCGECAMCDPGCFGGSGTGPIQVASVMITLLIPSVDAVARELLMATLEELSQEQLKRFRHKLRDAPLDGRSIPWGRLERSDAVDLVDKLIEFYEPVPAVEMTRQVLKRSDIRDVASRLKQQQLQKLGPTSVLLSVSAFKKKYREHVLRQHAKVKERNARSVKINKRFTKLLIAPGTGAVEDELLGPLGEPEPERARRSDTHTFNRLFRGNDEESSQPLTVVLQGPAGIGKTMAAKKILYDWAAGKLYHSQVDFAFFMPCGELLERPGKRSLADLVLDQCPDRAWPVKRILAQPNRLLFILDGADELPTLPSSEATPCKDPLEATSGLRVLSGLLSQELLPGARLLVTTRHAATGRLQGRLCSPQCAEIRGFSDKDKKKYFFKFFRDERKAERAYRFVKENETLFALCFVPFVCWIVCTVLQQQLELGRDLSRTSKTTTSVYLLFITSMLKSAGTNGPRVQGELRTLCRLAREGILDHHKAQFSEEDLEKLKLRGSQVQTIFLNKKEIPGVLKTEVTYQFIDQSFQEFLAALSYLLEAERTPGTPAGGVQKLLNSDAELRGHLALTTRFLFGLLNTEGLRDIGNHFGCVVPDHVKKDTLRWVQGQSHPKGPPVGAKKTAELEDIEDAEEEEEEEEDLNFGLELLYCLYETQEEDFVRQALSSLPEIVLERVRLTRMDLEVLNYCVQCCPDGQALRLVSCGLVAAKEKKKKKKSLVKRLKGSQSTKKQPPVSLLRPLCETMTTPKCHLSVLILSHCRLPDAVCRDLSEALKVAPALRELGLLQSRLTNTGLRLLCEGLAWPKCQVKTLRMQLPDLQEVINYLVIVLQQSPVLTTLDLSGCQLPGVIVEPLCAALKHPKCSLKTLSLTSVELSENSLRDLQAVKTSKPDLSIIYSK

Target ORF information:

RefSeq Version	XM_006536149.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus NLR family, pyrin domain containing 6 (Nlrp6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006536149.3

ORF Insert Sequence:

ATGTATTGCC CTGGGGCTCC ATGTGGAGAA TGTGCAATGT GTGACCCGGG GTGCTTTGGA 
GGTTCAGGGA CAGGTCCTAT TCAGGTCGCA TCAGTGATGA TAACCCTTCT CATCCCCAGC 
GTGGATGCAG TGGCAAGGGA GCTGCTTATG GCTACACTGG AGGAGCTGAG CCAGGAGCAG 
CTGAAGCGCT TCCGCCACAA GCTAAGGGAT GCGCCCCTGG ATGGCCGCAG CATCCCGTGG 
GGGCGACTGG AGCGCTCAGA CGCTGTGGAC CTTGTCGACA AGCTCATTGA GTTCTATGAG 
CCAGTGCCAG CTGTAGAAAT GACCCGGCAG GTCCTGAAGA GGTCGGATAT TCGAGATGTG 
GCCTCGCGAC TTAAGCAACA GCAGCTACAG AAGCTCGGCC CCACCTCGGT GCTTCTCTCC 
GTGTCAGCGT TCAAGAAGAA GTACCGCGAG CACGTGCTAC GACAGCATGC TAAGGTGAAG 
GAGAGGAATG CTCGCTCTGT GAAGATCAAC AAGCGCTTCA CCAAGCTGCT CATCGCTCCG 
GGGACCGGCG CTGTGGAGGA CGAGCTGCTG GGGCCGTTGG GGGAGCCGGA GCCCGAACGC 
GCTCGGCGCT CGGACACGCA CACTTTTAAT CGGCTCTTCC GGGGAAATGA TGAAGAGAGC 
TCGCAGCCGC TGACCGTGGT GCTGCAGGGC CCGGCAGGCA TCGGCAAAAC CATGGCCGCC 
AAGAAAATCC TCTATGACTG GGCAGCAGGT AAGCTATACC ACAGCCAGGT GGACTTTGCC 
TTCTTCATGC CGTGCGGCGA GCTGCTGGAG CGGCCGGGAA AGCGCAGCTT GGCGGACCTG 
GTGCTGGACC AGTGCCCGGA CCGCGCTTGG CCAGTGAAGC GGATACTGGC GCAACCCAAT 
CGCCTACTGT TCATCCTGGA CGGTGCAGAC GAGCTGCCTA CTTTACCATC CTCAGAGGCC 
ACTCCCTGCA AAGACCCTTT GGAGGCTACA AGTGGCTTGA GAGTGCTGAG CGGGCTGCTG 
AGCCAGGAGC TGTTACCAGG AGCTCGCTTG CTAGTGACTA CACGCCATGC CGCTACAGGG 
AGGCTGCAGG GCAGATTGTG CTCGCCACAG TGCGCAGAAA TACGCGGCTT CTCAGACAAA 
GACAAAAAAA AGTATTTCTT CAAGTTCTTC CGGGACGAGA GGAAGGCAGA GCGCGCTTAC 
CGCTTCGTGA AAGAGAACGA GACGCTGTTT GCACTGTGCT TTGTGCCCTT CGTGTGCTGG 
ATCGTGTGCA CAGTGCTGCA GCAGCAGCTA GAGCTGGGCC GGGATCTCTC TCGTACCTCC 
AAGACCACTA CTTCTGTGTA CCTGCTCTTC ATCACCAGCA TGCTGAAGTC TGCAGGCACC 
AATGGACCCC GGGTTCAGGG AGAGCTGAGA ACGCTGTGTC GCCTGGCCAG GGAGGGCATC 
CTGGATCATC ATAAAGCACA ATTCTCAGAA GAGGACCTGG AGAAATTGAA GCTTCGGGGT 
TCCCAAGTTC AGACAATATT TCTCAACAAG AAAGAGATAC CAGGAGTGCT AAAAACTGAG 
GTCACCTACC AGTTCATTGA CCAGAGCTTC CAGGAGTTCT TGGCTGCATT GTCATACCTA 
CTAGAAGCTG AGCGAACTCC GGGGACGCCC GCAGGCGGTG TGCAGAAGCT CCTGAACTCT 
GACGCGGAGC TACGTGGTCA TCTTGCACTG ACCACCCGAT TCCTCTTTGG CCTGCTAAAT 
ACAGAGGGGC TTCGTGACAT TGGAAACCAT TTTGGCTGTG TGGTGCCAGA TCATGTGAAA 
AAGGACACCC TGCGGTGGGT ACAAGGACAG AGCCACCCCA AGGGGCCACC AGTAGGGGCA 
AAAAAGACTG CTGAGCTGGA GGACATCGAG GACGCAGAGG AGGAGGAGGA GGAAGAGGAG 
GACCTCAATT TTGGACTGGA GCTGCTGTAC TGCCTGTATG AGACACAGGA GGAGGATTTT 
GTTCGACAGG CTCTCAGCAG CCTTCCAGAG ATAGTACTGG AGCGAGTCAG GTTGACCCGC 
ATGGACCTTG AAGTTCTGAA TTACTGCGTG CAGTGCTGCC CAGATGGCCA GGCTCTGAGA 
CTGGTGAGCT GTGGGCTGGT GGCGGCAAAG GAGAAGAAGA AGAAGAAGAA GAGCCTGGTG 
AAGCGGCTGA AGGGCTCTCA AAGCACCAAG AAACAACCCC CAGTCTCCTT GCTGCGTCCA 
CTCTGTGAGA CAATGACTAC CCCGAAATGT CATCTGAGTG TTCTGATCTT GTCACACTGC 
AGACTCCCTG ATGCAGTTTG CCGAGACCTT TCCGAGGCCC TGAAGGTAGC TCCTGCCCTA 
AGGGAGTTGG GCCTCCTCCA GAGCCGGCTC ACCAACACAG GCCTGCGTTT ACTGTGCGAA 
GGCCTGGCTT GGCCCAAGTG CCAGGTGAAG ACACTCAGGA TGCAGCTGCC TGACCTCCAA 
GAGGTGATCA ATTACTTGGT CATCGTGCTC CAGCAGAGCC CAGTCCTGAC CACTCTGGAC 
CTCAGTGGCT GTCAGCTGCC TGGCGTCATT GTGGAACCTC TGTGTGCAGC CCTGAAGCAC 
CCTAAATGCT CCCTAAAGAC CCTCAGTCTG ACCTCTGTGG AGCTGAGTGA GAACTCACTG 
AGGGATCTTC AAGCTGTGAA GACATCAAAG CCAGATCTGT CCATCATATA TTCAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nlrp6 ( XM_006536149.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006536212.1 Mus musculus NLR family, pyrin domain containing 6 (Nlrp6), transcript variant X1, mRNA.

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CloneID	OMu40036
Clone ID Related Accession (Same CDS sequence)	XM_006536149.4 , XM_006536149.3
Accession Version	XM_006536149.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2700bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	NACHT, LRR and PYD domains-containing protein 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006536149.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTATTGCC CTGGGGCTCC ATGTGGAGAA TGTGCAATGT GTGACCCGGG GTGCTTTGGA 
GGTTCAGGGA CAGGTCCTAT TCAGGTCGCA TCAGTGATGA TAACCCTTCT CATCCCCAGC 
GTGGATGCAG TGGCAAGGGA GCTGCTTATG GCTACACTGG AGGAGCTGAG CCAGGAGCAG 
CTGAAGCGCT TCCGCCACAA GCTAAGGGAT GCGCCCCTGG ATGGCCGCAG CATCCCGTGG 
GGGCGACTGG AGCGCTCAGA CGCTGTGGAC CTTGTCGACA AGCTCATTGA GTTCTATGAG 
CCAGTGCCAG CTGTAGAAAT GACCCGGCAG GTCCTGAAGA GGTCGGATAT TCGAGATGTG 
GCCTCGCGAC TTAAGCAACA GCAGCTACAG AAGCTCGGCC CCACCTCGGT GCTTCTCTCC 
GTGTCAGCGT TCAAGAAGAA GTACCGCGAG CACGTGCTAC GACAGCATGC TAAGGTGAAG 
GAGAGGAATG CTCGCTCTGT GAAGATCAAC AAGCGCTTCA CCAAGCTGCT CATCGCTCCG 
GGGACCGGCG CTGTGGAGGA CGAGCTGCTG GGGCCGTTGG GGGAGCCGGA GCCCGAACGC 
GCTCGGCGCT CGGACACGCA CACTTTTAAT CGGCTCTTCC GGGGAAATGA TGAAGAGAGC 
TCGCAGCCGC TGACCGTGGT GCTGCAGGGC CCGGCAGGCA TCGGCAAAAC CATGGCCGCC 
AAGAAAATCC TCTATGACTG GGCAGCAGGT AAGCTATACC ACAGCCAGGT GGACTTTGCC 
TTCTTCATGC CGTGCGGCGA GCTGCTGGAG CGGCCGGGAA AGCGCAGCTT GGCGGACCTG 
GTGCTGGACC AGTGCCCGGA CCGCGCTTGG CCAGTGAAGC GGATACTGGC GCAACCCAAT 
CGCCTACTGT TCATCCTGGA CGGTGCAGAC GAGCTGCCTA CTTTACCATC CTCAGAGGCC 
ACTCCCTGCA AAGACCCTTT GGAGGCTACA AGTGGCTTGA GAGTGCTGAG CGGGCTGCTG 
AGCCAGGAGC TGTTACCAGG AGCTCGCTTG CTAGTGACTA CACGCCATGC CGCTACAGGG 
AGGCTGCAGG GCAGATTGTG CTCGCCACAG TGCGCAGAAA TACGCGGCTT CTCAGACAAA 
GACAAAAAAA AGTATTTCTT CAAGTTCTTC CGGGACGAGA GGAAGGCAGA GCGCGCTTAC 
CGCTTCGTGA AAGAGAACGA GACGCTGTTT GCACTGTGCT TTGTGCCCTT CGTGTGCTGG 
ATCGTGTGCA CAGTGCTGCA GCAGCAGCTA GAGCTGGGCC GGGATCTCTC TCGTACCTCC 
AAGACCACTA CTTCTGTGTA CCTGCTCTTC ATCACCAGCA TGCTGAAGTC TGCAGGCACC 
AATGGACCCC GGGTTCAGGG AGAGCTGAGA ACGCTGTGTC GCCTGGCCAG GGAGGGCATC 
CTGGATCATC ATAAAGCACA ATTCTCAGAA GAGGACCTGG AGAAATTGAA GCTTCGGGGT 
TCCCAAGTTC AGACAATATT TCTCAACAAG AAAGAGATAC CAGGAGTGCT AAAAACTGAG 
GTCACCTACC AGTTCATTGA CCAGAGCTTC CAGGAGTTCT TGGCTGCATT GTCATACCTA 
CTAGAAGCTG AGCGAACTCC GGGGACGCCC GCAGGCGGTG TGCAGAAGCT CCTGAACTCT 
GACGCGGAGC TACGTGGTCA TCTTGCACTG ACCACCCGAT TCCTCTTTGG CCTGCTAAAT 
ACAGAGGGGC TTCGTGACAT TGGAAACCAT TTTGGCTGTG TGGTGCCAGA TCATGTGAAA 
AAGGACACCC TGCGGTGGGT ACAAGGACAG AGCCACCCCA AGGGGCCACC AGTAGGGGCA 
AAAAAGACTG CTGAGCTGGA GGACATCGAG GACGCAGAGG AGGAGGAGGA GGAAGAGGAG 
GACCTCAATT TTGGACTGGA GCTGCTGTAC TGCCTGTATG AGACACAGGA GGAGGATTTT 
GTTCGACAGG CTCTCAGCAG CCTTCCAGAG ATAGTACTGG AGCGAGTCAG GTTGACCCGC 
ATGGACCTTG AAGTTCTGAA TTACTGCGTG CAGTGCTGCC CAGATGGCCA GGCTCTGAGA 
CTGGTGAGCT GTGGGCTGGT GGCGGCAAAG GAGAAGAAGA AGAAGAAGAA GAGCCTGGTG 
AAGCGGCTGA AGGGCTCTCA AAGCACCAAG AAACAACCCC CAGTCTCCTT GCTGCGTCCA 
CTCTGTGAGA CAATGACTAC CCCGAAATGT CATCTGAGTG TTCTGATCTT GTCACACTGC 
AGACTCCCTG ATGCAGTTTG CCGAGACCTT TCCGAGGCCC TGAAGGTAGC TCCTGCCCTA 
AGGGAGTTGG GCCTCCTCCA GAGCCGGCTC ACCAACACAG GCCTGCGTTT ACTGTGCGAA 
GGCCTGGCTT GGCCCAAGTG CCAGGTGAAG ACACTCAGGA TGCAGCTGCC TGACCTCCAA 
GAGGTGATCA ATTACTTGGT CATCGTGCTC CAGCAGAGCC CAGTCCTGAC CACTCTGGAC 
CTCAGTGGCT GTCAGCTGCC TGGCGTCATT GTGGAACCTC TGTGTGCAGC CCTGAAGCAC 
CCTAAATGCT CCCTAAAGAC CCTCAGTCTG ACCTCTGTGG AGCTGAGTGA GAACTCACTG 
AGGGATCTTC AAGCTGTGAA GACATCAAAG CCAGATCTGT CCATCATATA TTCAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006536212.1
CDS	16..2715
Translation	MYCPGAPCGECAMCDPGCFGGSGTGPIQVASVMITLLIPSVDAVARELLMATLEELSQEQLKRFRHKLRDAPLDGRSIPWGRLERSDAVDLVDKLIEFYEPVPAVEMTRQVLKRSDIRDVASRLKQQQLQKLGPTSVLLSVSAFKKKYREHVLRQHAKVKERNARSVKINKRFTKLLIAPGTGAVEDELLGPLGEPEPERARRSDTHTFNRLFRGNDEESSQPLTVVLQGPAGIGKTMAAKKILYDWAAGKLYHSQVDFAFFMPCGELLERPGKRSLADLVLDQCPDRAWPVKRILAQPNRLLFILDGADELPTLPSSEATPCKDPLEATSGLRVLSGLLSQELLPGARLLVTTRHAATGRLQGRLCSPQCAEIRGFSDKDKKKYFFKFFRDERKAERAYRFVKENETLFALCFVPFVCWIVCTVLQQQLELGRDLSRTSKTTTSVYLLFITSMLKSAGTNGPRVQGELRTLCRLAREGILDHHKAQFSEEDLEKLKLRGSQVQTIFLNKKEIPGVLKTEVTYQFIDQSFQEFLAALSYLLEAERTPGTPAGGVQKLLNSDAELRGHLALTTRFLFGLLNTEGLRDIGNHFGCVVPDHVKKDTLRWVQGQSHPKGPPVGAKKTAELEDIEDAEEEEEEEEDLNFGLELLYCLYETQEEDFVRQALSSLPEIVLERVRLTRMDLEVLNYCVQCCPDGQALRLVSCGLVAAKEKKKKKKSLVKRLKGSQSTKKQPPVSLLRPLCETMTTPKCHLSVLILSHCRLPDAVCRDLSEALKVAPALRELGLLQSRLTNTGLRLLCEGLAWPKCQVKTLRMQLPDLQEVINYLVIVLQQSPVLTTLDLSGCQLPGVIVEPLCAALKHPKCSLKTLSLTSVELSENSLRDLQAVKTSKPDLSIIYSK

Target ORF information:

RefSeq Version	XM_006536149.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus NLR family, pyrin domain containing 6 (Nlrp6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006536149.4

ORF Insert Sequence:

ATGTATTGCC CTGGGGCTCC ATGTGGAGAA TGTGCAATGT GTGACCCGGG GTGCTTTGGA 
GGTTCAGGGA CAGGTCCTAT TCAGGTCGCA TCAGTGATGA TAACCCTTCT CATCCCCAGC 
GTGGATGCAG TGGCAAGGGA GCTGCTTATG GCTACACTGG AGGAGCTGAG CCAGGAGCAG 
CTGAAGCGCT TCCGCCACAA GCTAAGGGAT GCGCCCCTGG ATGGCCGCAG CATCCCGTGG 
GGGCGACTGG AGCGCTCAGA CGCTGTGGAC CTTGTCGACA AGCTCATTGA GTTCTATGAG 
CCAGTGCCAG CTGTAGAAAT GACCCGGCAG GTCCTGAAGA GGTCGGATAT TCGAGATGTG 
GCCTCGCGAC TTAAGCAACA GCAGCTACAG AAGCTCGGCC CCACCTCGGT GCTTCTCTCC 
GTGTCAGCGT TCAAGAAGAA GTACCGCGAG CACGTGCTAC GACAGCATGC TAAGGTGAAG 
GAGAGGAATG CTCGCTCTGT GAAGATCAAC AAGCGCTTCA CCAAGCTGCT CATCGCTCCG 
GGGACCGGCG CTGTGGAGGA CGAGCTGCTG GGGCCGTTGG GGGAGCCGGA GCCCGAACGC 
GCTCGGCGCT CGGACACGCA CACTTTTAAT CGGCTCTTCC GGGGAAATGA TGAAGAGAGC 
TCGCAGCCGC TGACCGTGGT GCTGCAGGGC CCGGCAGGCA TCGGCAAAAC CATGGCCGCC 
AAGAAAATCC TCTATGACTG GGCAGCAGGT AAGCTATACC ACAGCCAGGT GGACTTTGCC 
TTCTTCATGC CGTGCGGCGA GCTGCTGGAG CGGCCGGGAA AGCGCAGCTT GGCGGACCTG 
GTGCTGGACC AGTGCCCGGA CCGCGCTTGG CCAGTGAAGC GGATACTGGC GCAACCCAAT 
CGCCTACTGT TCATCCTGGA CGGTGCAGAC GAGCTGCCTA CTTTACCATC CTCAGAGGCC 
ACTCCCTGCA AAGACCCTTT GGAGGCTACA AGTGGCTTGA GAGTGCTGAG CGGGCTGCTG 
AGCCAGGAGC TGTTACCAGG AGCTCGCTTG CTAGTGACTA CACGCCATGC CGCTACAGGG 
AGGCTGCAGG GCAGATTGTG CTCGCCACAG TGCGCAGAAA TACGCGGCTT CTCAGACAAA 
GACAAAAAAA AGTATTTCTT CAAGTTCTTC CGGGACGAGA GGAAGGCAGA GCGCGCTTAC 
CGCTTCGTGA AAGAGAACGA GACGCTGTTT GCACTGTGCT TTGTGCCCTT CGTGTGCTGG 
ATCGTGTGCA CAGTGCTGCA GCAGCAGCTA GAGCTGGGCC GGGATCTCTC TCGTACCTCC 
AAGACCACTA CTTCTGTGTA CCTGCTCTTC ATCACCAGCA TGCTGAAGTC TGCAGGCACC 
AATGGACCCC GGGTTCAGGG AGAGCTGAGA ACGCTGTGTC GCCTGGCCAG GGAGGGCATC 
CTGGATCATC ATAAAGCACA ATTCTCAGAA GAGGACCTGG AGAAATTGAA GCTTCGGGGT 
TCCCAAGTTC AGACAATATT TCTCAACAAG AAAGAGATAC CAGGAGTGCT AAAAACTGAG 
GTCACCTACC AGTTCATTGA CCAGAGCTTC CAGGAGTTCT TGGCTGCATT GTCATACCTA 
CTAGAAGCTG AGCGAACTCC GGGGACGCCC GCAGGCGGTG TGCAGAAGCT CCTGAACTCT 
GACGCGGAGC TACGTGGTCA TCTTGCACTG ACCACCCGAT TCCTCTTTGG CCTGCTAAAT 
ACAGAGGGGC TTCGTGACAT TGGAAACCAT TTTGGCTGTG TGGTGCCAGA TCATGTGAAA 
AAGGACACCC TGCGGTGGGT ACAAGGACAG AGCCACCCCA AGGGGCCACC AGTAGGGGCA 
AAAAAGACTG CTGAGCTGGA GGACATCGAG GACGCAGAGG AGGAGGAGGA GGAAGAGGAG 
GACCTCAATT TTGGACTGGA GCTGCTGTAC TGCCTGTATG AGACACAGGA GGAGGATTTT 
GTTCGACAGG CTCTCAGCAG CCTTCCAGAG ATAGTACTGG AGCGAGTCAG GTTGACCCGC 
ATGGACCTTG AAGTTCTGAA TTACTGCGTG CAGTGCTGCC CAGATGGCCA GGCTCTGAGA 
CTGGTGAGCT GTGGGCTGGT GGCGGCAAAG GAGAAGAAGA AGAAGAAGAA GAGCCTGGTG 
AAGCGGCTGA AGGGCTCTCA AAGCACCAAG AAACAACCCC CAGTCTCCTT GCTGCGTCCA 
CTCTGTGAGA CAATGACTAC CCCGAAATGT CATCTGAGTG TTCTGATCTT GTCACACTGC 
AGACTCCCTG ATGCAGTTTG CCGAGACCTT TCCGAGGCCC TGAAGGTAGC TCCTGCCCTA 
AGGGAGTTGG GCCTCCTCCA GAGCCGGCTC ACCAACACAG GCCTGCGTTT ACTGTGCGAA 
GGCCTGGCTT GGCCCAAGTG CCAGGTGAAG ACACTCAGGA TGCAGCTGCC TGACCTCCAA 
GAGGTGATCA ATTACTTGGT CATCGTGCTC CAGCAGAGCC CAGTCCTGAC CACTCTGGAC 
CTCAGTGGCT GTCAGCTGCC TGGCGTCATT GTGGAACCTC TGTGTGCAGC CCTGAAGCAC 
CCTAAATGCT CCCTAAAGAC CCTCAGTCTG ACCTCTGTGG AGCTGAGTGA GAACTCACTG 
AGGGATCTTC AAGCTGTGAA GACATCAAAG CCAGATCTGT CCATCATATA TTCAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Clostridium butyricum regulates visceral hypersensitivity of irritable bowel syndrome by inhibiting colonic mucous low grade inflammation through its action on NLRP6.
Acta biochimica et biophysica Sinica(2018 Jan)
Zhao K,Yu L,Wang X,He Y,Lu B

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Nlrp6 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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