Gene Symbol | SLC6A4 |
Entrez Gene ID | 574140 |
Full Name | solute carrier family 6 member 4 |
Synonyms | 5-HTT,SERT |
Gene Type | protein-coding |
Organism | Macaca mulatta(Rhesus monkey) |
ORF » Species Summary » Macaca mulatta » SLC6A4 cDNA ORF clone
Gene Symbol | SLC6A4 |
Entrez Gene ID | 574140 |
Full Name | solute carrier family 6 member 4 |
Synonyms | 5-HTT,SERT |
Gene Type | protein-coding |
Organism | Macaca mulatta(Rhesus monkey) |
mRNA | Protein | Name |
---|---|---|
NM_001032823.1 | NP_001027995.1 | sodium-dependent serotonin transporter |
XM_015118835.2 | XP_014974321.1 | sodium-dependent serotonin transporter isoform X1 |
XM_015118836.2 | XP_014974322.1 | sodium-dependent serotonin transporter isoform X1 |
XM_015118835.1 | XP_014974321.1 | sodium-dependent serotonin transporter isoform X1 |
XM_015118836.1 | XP_014974322.1 | sodium-dependent serotonin transporter isoform X1 |
XM_028835447.1 | XP_028691280.1 | sodium-dependent serotonin transporter isoform X1 |
Xenopus tropicalis (tropical clawed frog) | LOC100493853 | XP_002943421.2 |
Bos taurus (cattle) | SLC6A4 | NP_777034.1 |
Gallus gallus (chicken) | SLC6A4 | NP_998737.1 |
Pan troglodytes (chimpanzee) | SLC6A4 | XP_001135066.2 |
Rattus norvegicus (Norway rat) | Slc6a4 | NP_037166.2 |
SLC6A4 | NP_001027995.1 | |
Danio rerio (zebrafish) | slc6a4a | NP_001035061.1 |
Homo sapiens (human) | SLC6A4 | NP_001036.1 |
Canis lupus familiaris (dog) | SLC6A4 | NP_001104241.1 |
Mus musculus (house mouse) | Slc6a4 | NP_034614.2 |
Sensory Processing in Rhesus Monkeys: Developmental Continuity, Prenatal Treatment, and Genetic Influences.
Schneider ML, Moore CF, Adkins M, Barr CS, Larson JA, Resch LM, Roberts A
Child development88(1)183-197(2017 Jan)
Serotonin transporter genotype affects serotonin 5-HT1A binding in primates.
Christian BT, Wooten DW, Hillmer AT, Tudorascu DL, Converse AK, Moore CF, Ahlers EO, Barnhart TE, Kalin NH, Barr CS, Schneider ML
The Journal of neuroscience : the official journal of the Society for Neuroscience33(6)2512-6(2013 Feb)
The relation of developmental changes in brain serotonin transporter (5HTT) and 5HT1A receptor binding to emotional behavior in female rhesus monkeys: effects of social status and 5HTT genotype.
Embree M, Michopoulos V, Votaw JR, Voll RJ, Mun J, Stehouwer JS, Goodman MM, Wilson ME, S?nchez MM
Neuroscience22883-100(2013 Jan)
The serotonin transporter gene is a substrate for age and stress dependent epigenetic regulation in rhesus macaque brain: potential roles in genetic selection and gene ? environment interactions.
Lindell SG, Yuan Q, Zhou Z, Goldman D, Thompson RC, Lopez JF, Suomi SJ, Higley JD, Barr CS
Development and psychopathology24(4)1391-400(2012 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Rhesus monkeys carrying the short rh5-HTTLPR allele have less optimal neonatal sensory scores than monkeys homozygous for the long allele.
Title: Sensory Processing in Rhesus Monkeys: Developmental Continuity, Prenatal Treatment, and Genetic Influences.
A significant 5-HTTLPR effect on receptor binding at the 5-HT1A receptor site is found in animals possessing this polymorphism.
Title: Serotonin transporter genotype affects serotonin 5-HT1A binding in primates.
An effect of social status is detected on 5HTT levels in the developing orbitofrontal cortex partly influenced by exposure to the social stress of subordination.
Title: The relation of developmental changes in brain serotonin transporter (5HTT) and 5HT1A receptor binding to emotional behavior in female rhesus monkeys: effects of social status and 5HTT genotype.
Study reports evidence for selection at the SLC6A4 gene and epigenetic reorganization according to genotype, stress, and age.
Title: The serotonin transporter gene is a substrate for age and stress dependent epigenetic regulation in rhesus macaque brain: potential roles in genetic selection and gene ? environment interactions.
We find that the short allele of the rh5-HTTLPR is associated with reduced surface SERT binding, which is correlated on an individual basis with serotonin uptake rates.
Title: Differential serotonin transport is linked to the rh5-HTTLPR in peripheral blood cells.
The following SLC6A4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC6A4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMb00123 | |
Clone ID Related Accession (Same CDS sequence) | NM_001032823.1 , XM_015118835.2 , XM_015118836.2 , XM_015118835.1 , XM_015118836.1 , XM_028835447.1 | |
Accession Version | NM_001032823.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1893bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-21 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | sodium-dependent serotonin transporter | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF285761.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF285761.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01830805 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGAGACCA CACCCTTAAA TTCTCAGAAG CAGCTCTCAG CGTGTAAGGA TGGAGAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001027995.1 |
CDS | 1..1893 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001032823.1 |
1 | ATGGAGACCA CACCCTTAAA TTCTCAGAAG CAGCTCTCAG CGTGTAAGGA TGGAGAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb00123 | |
Clone ID Related Accession (Same CDS sequence) | NM_001032823.1 , XM_015118835.2 , XM_015118836.2 , XM_015118835.1 , XM_015118836.1 , XM_028835447.1 | |
Accession Version | XM_015118835.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1893bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-25 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | sodium-dependent serotonin transporter isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041769.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 23, 2019 this sequence version replaced XM_015118835.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGACCA CACCCTTAAA TTCTCAGAAG CAGCTCTCAG CGTGTAAGGA TGGAGAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_014974321.1 |
CDS | 385..2277 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015118835.2 |
1 | ATGGAGACCA CACCCTTAAA TTCTCAGAAG CAGCTCTCAG CGTGTAAGGA TGGAGAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb00123 | |
Clone ID Related Accession (Same CDS sequence) | NM_001032823.1 , XM_015118835.2 , XM_015118836.2 , XM_015118835.1 , XM_015118836.1 , XM_028835447.1 | |
Accession Version | XM_015118836.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1893bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-25 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | sodium-dependent serotonin transporter isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041769.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 23, 2019 this sequence version replaced XM_015118836.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGACCA CACCCTTAAA TTCTCAGAAG CAGCTCTCAG CGTGTAAGGA TGGAGAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_014974322.1 |
CDS | 350..2242 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015118836.2 |
1 | ATGGAGACCA CACCCTTAAA TTCTCAGAAG CAGCTCTCAG CGTGTAAGGA TGGAGAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb00123 | |
Clone ID Related Accession (Same CDS sequence) | NM_001032823.1 , XM_015118835.2 , XM_015118836.2 , XM_015118835.1 , XM_015118836.1 , XM_028835447.1 | |
Accession Version | XM_015118835.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1893bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-12-20 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | sodium-dependent serotonin transporter isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014805556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Macaca mulatta Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGACCA CACCCTTAAA TTCTCAGAAG CAGCTCTCAG CGTGTAAGGA TGGAGAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_014974321.1 |
CDS | 378..2270 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015118835.1 |
1 | ATGGAGACCA CACCCTTAAA TTCTCAGAAG CAGCTCTCAG CGTGTAAGGA TGGAGAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb00123 | |
Clone ID Related Accession (Same CDS sequence) | NM_001032823.1 , XM_015118835.2 , XM_015118836.2 , XM_015118835.1 , XM_015118836.1 , XM_028835447.1 | |
Accession Version | XM_015118836.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1893bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-12-20 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | sodium-dependent serotonin transporter isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014805556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Macaca mulatta Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGACCA CACCCTTAAA TTCTCAGAAG CAGCTCTCAG CGTGTAAGGA TGGAGAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_014974322.1 |
CDS | 500..2392 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015118836.1 |
1 | ATGGAGACCA CACCCTTAAA TTCTCAGAAG CAGCTCTCAG CGTGTAAGGA TGGAGAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb00123 | |
Clone ID Related Accession (Same CDS sequence) | NM_001032823.1 , XM_015118835.2 , XM_015118836.2 , XM_015118835.1 , XM_015118836.1 , XM_028835447.1 | |
Accession Version | XM_028835447.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1893bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-25 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | sodium-dependent serotonin transporter isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041769.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGACCA CACCCTTAAA TTCTCAGAAG CAGCTCTCAG CGTGTAAGGA TGGAGAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_028691280.1 |
CDS | 284..2176 |
Translation |
Target ORF information:
Target ORF information:
|
XM_028835447.1 |
1 | ATGGAGACCA CACCCTTAAA TTCTCAGAAG CAGCTCTCAG CGTGTAAGGA TGGAGAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Sensory Processing in Rhesus Monkeys: Developmental Continuity, Prenatal Treatment, and Genetic Influences. |
Serotonin transporter genotype affects serotonin 5-HT1A binding in primates. |
The relation of developmental changes in brain serotonin transporter (5HTT) and 5HT1A receptor binding to emotional behavior in female rhesus monkeys: effects of social status and 5HTT genotype. |
The serotonin transporter gene is a substrate for age and stress dependent epigenetic regulation in rhesus macaque brain: potential roles in genetic selection and gene ? environment interactions. |