MVP cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MVP
Entrez Gene ID	9961
Full Name	major vault protein
Synonyms	LRP,VAULT1
General protein information	Preferred Names major vault protein Names major vault protein lung resistance-related protein testicular secretory protein Li 30
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16p11.2
Summary	This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012].
Disorder MIM:	605088

mRNA and Protein(s)

mRNA	Protein	Name
NM_017458.3	NP_059447.2	major vault protein isoform 1
NM_005115.4	NP_005106.2	major vault protein isoform 1
NM_001293204.1	NP_001280133.1	major vault protein isoform 2
NM_005115.5	NP_005106.2	major vault protein isoform 1
NM_001293205.1	NP_001280134.1	major vault protein isoform 3

Pathways from BioSystems

Homologies

	LOC706736	XP_002808339.1
Rattus norvegicus (Norway rat)	Mvp	NP_073206.2
Danio rerio (zebrafish)	mvp	NP_958482.1
Canis lupus familiaris (dog)	MVP	XP_536910.3
Bos taurus (cattle)	MVP	NP_001030394.1
Gallus gallus (chicken)	MVP	NP_001006336.1
Xenopus tropicalis (tropical clawed frog)	mvp	NP_001072293.1
Homo sapiens (human)	MVP	NP_005106.2
Mus musculus (house mouse)	Mvp	NP_542369.2

Gene Ontology
Bibliography

Related articles in PubMed

vPARP Adjusts MVP Expression in Drug-resistant Cell Lines in Conjunction with MDR Proteins.
Wojtowicz K, Januchowski R, Nowicki M, Zabel M
Anticancer research37(6)3015-3023(2017 06)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Major vault protein is important in the drug resistance of cancer cells, but it requires the presence of vPARP for full activity
Title: vPARP Adjusts MVP Expression in Drug-resistant Cell Lines in Conjunction with MDR Proteins.

Study found significant upregulation of MVP and BCRP whereas MRP1 and UGT1A4 were unaltered in drug resistant epilepsy brains. While upregulation of BCRP was significantly higher in mesial temporal lobe epilepsy (9.34+/-0.45; p<0.05), upregulation of MVP was significantly higher in focal cortical dysplasia (2.94+/-0.65; p<0.01).
Title: Upregulation of breast cancer resistance protein and major vault protein in drug resistant epilepsy.

involved in doxorubicin resistance of non-small cell lung cancer
Title: Mechanisms underlying lung resistance-related protein (LRP)-mediated doxorubicin resistance of non-small cell lung cancer cells.

Taxus chinensis var.-mediated downregulation of MRP1, MDR1, and LRP might contribute to the reversal of drug resistance in non-small cell lung cancer stem cells.
Title: Reversal of cisplatin resistance in non-small cell lung cancer stem cells by Taxus chinensis var.

We believe that for the first time, genetic variants at XRCC6 and MVP genes are associated with risk of more aggressive disease, and would be taken into account when assessing the malignancy of prostate cancer
Title: Association between single-nucleotide polymorphisms in DNA double-strand break repair genes and prostate cancer aggressiveness in the Spanish population.

The following MVP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MVP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27810	NM_017458.3 Latest version!	Homo sapiens major vault protein (MVP), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu27810	NM_005115.5 Latest version!	Homo sapiens major vault protein (MVP), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu27819	NM_001293204.1 Latest version!	Homo sapiens major vault protein (MVP), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu27821	NM_001293205.1 Latest version!	Homo sapiens major vault protein (MVP), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
View Old Accession Versions >>
OHu27810	NM_005115.4	Homo sapiens major vault protein (MVP), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MVP ( NM_017458.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_059447.2 Homo sapiens major vault protein (MVP), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu27810
Clone ID Related Accession (Same CDS sequence)	NM_017458.3 , NM_005115.4 , NM_005115.5
Accession Version	NM_017458.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2682bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	major vault protein isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA842337.1, BC008932.2, BU151678.1 and BM999583.1. On Nov 19, 2010 this sequence version replaced NM_017458.2. Transcript Variant: This variant (1, also known as L-MVP) is the longest transcript. Variants 1 and 2 encode the same isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.42325.1, SRR1803612.32638.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## regulatory uORF :: PMID: 11297743 ##RefSeq-Attributes-END##

ATGGCAACTG AAGAGTTCAT CATCCGCATC CCCCCATACC ACTATATCCA TGTGCTGGAC 
CAGAACAGCA ACGTGTCCCG TGTGGAGGTC GGGCCAAAGA CCTACATCCG GCAGGACAAT 
GAGAGGGTAC TGTTTGCCCC CATGCGCATG GTGACCGTCC CCCCACGTCA CTACTGCACA 
GTGGCCAACC CTGTGTCTCG GGATGCCCAG GGCTTGGTGC TGTTTGATGT CACAGGGCAA 
GTTCGGCTTC GCCACGCTGA CCTCGAGATC CGGCTGGCCC AGGACCCCTT CCCCCTGTAC 
CCAGGGGAGG TGCTGGAAAA GGACATCACA CCCCTGCAGG TGGTTCTGCC CAACACTGCC 
CTCCATCTAA AGGCGCTGCT TGATTTTGAG GATAAAGATG GAGACAAGGT GGTGGCAGGA 
GATGAGTGGC TTTTCGAGGG ACCTGGCACG TACATCCCCC GGAAGGAAGT GGAGGTCGTG 
GAGATCATTC AGGCCACCAT CATCAGGCAG AACCAGGCTC TGCGGCTCAG GGCCCGCAAG 
GAGTGCTGGG ACCGGGACGG CAAGGAGAGG GTGACAGGGG AAGAATGGCT GGTCACCACA 
GTAGGGGCGT ACCTCCCAGC GGTGTTTGAG GAGGTTCTGG ATTTGGTGGA CGCCGTCATC 
CTTACGGAAA AGACAGCCCT GCACCTCCGG GCTCGGCGGA ACTTCCGGGA CTTCAGGGGA 
GTGTCCCGCC GCACTGGGGA GGAGTGGCTG GTAACAGTGC AGGACACAGA GGCCCACGTG 
CCAGATGTCC ACGAGGAGGT GCTGGGGGTT GTGCCCATCA CCACCCTGGG CCCCCACAAC 
TACTGCGTGA TTCTCGACCC TGTCGGACCG GATGGCAAGA ATCAGCTGGG GCAGAAGCGC 
GTGGTCAAGG GAGAGAAGTC TTTTTTCCTC CAGCCAGGAG AGCAGCTGGA ACAAGGCATC 
CAGGATGTGT ATGTGCTGTC GGAGCAGCAG GGGCTGCTGC TGAGGGCCCT GCAGCCCCTG 
GAGGAGGGGG AGGATGAGGA GAAGGTCTCA CACCAGGCTG GGGACCACTG GCTCATCCGC 
GGACCCCTGG AGTATGTGCC ATCTGCCAAA GTGGAGGTGG TGGAGGAGCG CCAGGCCATC 
CCTCTAGACG AGAACGAGGG CATCTATGTG CAGGATGTCA AGACCGGAAA GGTGCGCGCT 
GTGATTGGAA GCACCTACAT GCTGACCCAG GACGAAGTCC TGTGGGAGAA AGAGCTGCCT 
CCCGGGGTGG AGGAGCTGCT GAACAAGGGG CAGGACCCTC TGGCAGACAG GGGTGAGAAG 
GACACAGCTA AGAGCCTCCA GCCCTTGGCG CCCCGGAACA AGACCCGTGT GGTCAGCTAC 
CGCGTGCCCC ACAACGCTGC GGTGCAGGTG TACGACTACC GAGAGAAGCG AGCCCGCGTG 
GTCTTCGGGC CTGAGCTGGT GTCGCTGGGT CCTGAGGAGC AGTTCACAGT GTTGTCCCTC 
TCAGCTGGGC GGCCCAAGCG TCCCCATGCC CGCCGTGCGC TCTGCCTGCT GCTGGGGCCT 
GACTTCTTCA CAGACGTCAT CACCATCGAA ACGGCGGATC ATGCCAGGCT GCAACTGCAG 
CTGGCCTACA ACTGGCACTT TGAGGTGAAT GACCGGAAGG ACCCCCAAGA GACGGCCAAG 
CTCTTTTCAG TGCCAGACTT TGTAGGTGAT GCCTGCAAAG CCATCGCATC CCGGGTGCGG 
GGGGCCGTGG CCTCTGTCAC TTTCGATGAC TTCCATAAGA ACTCAGCCCG CATCATTCGC 
ACTGCTGTCT TTGGCTTTGA GACCTCGGAA GCGAAGGGCC CCGATGGCAT GGCCCTGCCC 
AGGCCCCGGG ACCAGGCTGT CTTCCCCCAA AACGGGCTGG TGGTCAGCAG TGTGGACGTG 
CAGTCAGTGG AGCCTGTGGA TCAGAGGACC CGGGACGCCC TGCAACGCAG CGTCCAGCTG 
GCCATCGAGA TCACCACCAA CTCCCAGGAA GCGGCGGCCA AGCATGAGGC TCAGAGACTG 
GAGCAGGAAG CCCGCGGCCG GCTTGAGCGG CAGAAGATCC TGGACCAGTC AGAAGCCGAG 
AAAGCTCGCA AGGAACTTTT GGAGCTGGAG GCTCTGAGCA TGGCCGTGGA GAGCACCGGG 
ACTGCCAAGG CGGAGGCCGA GTCCCGTGCG GAGGCAGCCC GGATTGAGGG AGAAGGGTCC 
GTGCTGCAGG CCAAGCTAAA AGCACAGGCC TTGGCCATTG AAACGGAGGC TGAGCTCCAG 
AGGGTCCAGA AGGTCCGAGA GCTGGAACTG GTCTATGCCC GGGCCCAGCT GGAGCTGGAG 
GTGAGCAAGG CTCAGCAGCT GGCTGAGGTG GAGGTGAAGA AGTTCAAGCA GATGACAGAG 
GCCATAGGCC CCAGCACCAT CAGGGACCTT GCTGTGGCTG GGCCTGAGAT GCAGGTAAAA 
CTGCTCCAGT CCCTGGGCCT GAAATCAACC CTCATCACCG ATGGCTCCAC TCCCATCAAC 
CTCTTCAACA CAGCCTTTGG GCTGCTGGGG ATGGGGCCCG AGGGTCAGCC CCTGGGCAGA 
AGGGTGGCCA GTGGGCCCAG CCCTGGGGAG GGGATATCCC CCCAGTCTGC TCAGGCCCCT 
CAAGCTCCTG GAGACAACCA CGTGGTGCCT GTACTGCGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_059447.2
CDS	194..2875
Translation	MATEEFIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPMRMVTVPPRHYCTVANPVSRDAQGLVLFDVTGQVRLRHADLEIRLAQDPFPLYPGEVLEKDITPLQVVLPNTALHLKALLDFEDKDGDKVVAGDEWLFEGPGTYIPRKEVEVVEIIQATIIRQNQALRLRARKECWDRDGKERVTGEEWLVTTVGAYLPAVFEEVLDLVDAVILTEKTALHLRARRNFRDFRGVSRRTGEEWLVTVQDTEAHVPDVHEEVLGVVPITTLGPHNYCVILDPVGPDGKNQLGQKRVVKGEKSFFLQPGEQLEQGIQDVYVLSEQQGLLLRALQPLEEGEDEEKVSHQAGDHWLIRGPLEYVPSAKVEVVEERQAIPLDENEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELPPGVEELLNKGQDPLADRGEKDTAKSLQPLAPRNKTRVVSYRVPHNAAVQVYDYREKRARVVFGPELVSLGPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQLAYNWHFEVNDRKDPQETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIRTAVFGFETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSTPINLFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAPQAPGDNHVVPVLR

Target ORF information:

RefSeq Version	NM_017458.3
Organism	Homo sapiens(human)
Definition	Homo sapiens major vault protein (MVP), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017458.3

ORF Insert Sequence:

ATGGCAACTG AAGAGTTCAT CATCCGCATC CCCCCATACC ACTATATCCA TGTGCTGGAC 
CAGAACAGCA ACGTGTCCCG TGTGGAGGTC GGGCCAAAGA CCTACATCCG GCAGGACAAT 
GAGAGGGTAC TGTTTGCCCC CATGCGCATG GTGACCGTCC CCCCACGTCA CTACTGCACA 
GTGGCCAACC CTGTGTCTCG GGATGCCCAG GGCTTGGTGC TGTTTGATGT CACAGGGCAA 
GTTCGGCTTC GCCACGCTGA CCTCGAGATC CGGCTGGCCC AGGACCCCTT CCCCCTGTAC 
CCAGGGGAGG TGCTGGAAAA GGACATCACA CCCCTGCAGG TGGTTCTGCC CAACACTGCC 
CTCCATCTAA AGGCGCTGCT TGATTTTGAG GATAAAGATG GAGACAAGGT GGTGGCAGGA 
GATGAGTGGC TTTTCGAGGG ACCTGGCACG TACATCCCCC GGAAGGAAGT GGAGGTCGTG 
GAGATCATTC AGGCCACCAT CATCAGGCAG AACCAGGCTC TGCGGCTCAG GGCCCGCAAG 
GAGTGCTGGG ACCGGGACGG CAAGGAGAGG GTGACAGGGG AAGAATGGCT GGTCACCACA 
GTAGGGGCGT ACCTCCCAGC GGTGTTTGAG GAGGTTCTGG ATTTGGTGGA CGCCGTCATC 
CTTACGGAAA AGACAGCCCT GCACCTCCGG GCTCGGCGGA ACTTCCGGGA CTTCAGGGGA 
GTGTCCCGCC GCACTGGGGA GGAGTGGCTG GTAACAGTGC AGGACACAGA GGCCCACGTG 
CCAGATGTCC ACGAGGAGGT GCTGGGGGTT GTGCCCATCA CCACCCTGGG CCCCCACAAC 
TACTGCGTGA TTCTCGACCC TGTCGGACCG GATGGCAAGA ATCAGCTGGG GCAGAAGCGC 
GTGGTCAAGG GAGAGAAGTC TTTTTTCCTC CAGCCAGGAG AGCAGCTGGA ACAAGGCATC 
CAGGATGTGT ATGTGCTGTC GGAGCAGCAG GGGCTGCTGC TGAGGGCCCT GCAGCCCCTG 
GAGGAGGGGG AGGATGAGGA GAAGGTCTCA CACCAGGCTG GGGACCACTG GCTCATCCGC 
GGACCCCTGG AGTATGTGCC ATCTGCCAAA GTGGAGGTGG TGGAGGAGCG CCAGGCCATC 
CCTCTAGACG AGAACGAGGG CATCTATGTG CAGGATGTCA AGACCGGAAA GGTGCGCGCT 
GTGATTGGAA GCACCTACAT GCTGACCCAG GACGAAGTCC TGTGGGAGAA AGAGCTGCCT 
CCCGGGGTGG AGGAGCTGCT GAACAAGGGG CAGGACCCTC TGGCAGACAG GGGTGAGAAG 
GACACAGCTA AGAGCCTCCA GCCCTTGGCG CCCCGGAACA AGACCCGTGT GGTCAGCTAC 
CGCGTGCCCC ACAACGCTGC GGTGCAGGTG TACGACTACC GAGAGAAGCG AGCCCGCGTG 
GTCTTCGGGC CTGAGCTGGT GTCGCTGGGT CCTGAGGAGC AGTTCACAGT GTTGTCCCTC 
TCAGCTGGGC GGCCCAAGCG TCCCCATGCC CGCCGTGCGC TCTGCCTGCT GCTGGGGCCT 
GACTTCTTCA CAGACGTCAT CACCATCGAA ACGGCGGATC ATGCCAGGCT GCAACTGCAG 
CTGGCCTACA ACTGGCACTT TGAGGTGAAT GACCGGAAGG ACCCCCAAGA GACGGCCAAG 
CTCTTTTCAG TGCCAGACTT TGTAGGTGAT GCCTGCAAAG CCATCGCATC CCGGGTGCGG 
GGGGCCGTGG CCTCTGTCAC TTTCGATGAC TTCCATAAGA ACTCAGCCCG CATCATTCGC 
ACTGCTGTCT TTGGCTTTGA GACCTCGGAA GCGAAGGGCC CCGATGGCAT GGCCCTGCCC 
AGGCCCCGGG ACCAGGCTGT CTTCCCCCAA AACGGGCTGG TGGTCAGCAG TGTGGACGTG 
CAGTCAGTGG AGCCTGTGGA TCAGAGGACC CGGGACGCCC TGCAACGCAG CGTCCAGCTG 
GCCATCGAGA TCACCACCAA CTCCCAGGAA GCGGCGGCCA AGCATGAGGC TCAGAGACTG 
GAGCAGGAAG CCCGCGGCCG GCTTGAGCGG CAGAAGATCC TGGACCAGTC AGAAGCCGAG 
AAAGCTCGCA AGGAACTTTT GGAGCTGGAG GCTCTGAGCA TGGCCGTGGA GAGCACCGGG 
ACTGCCAAGG CGGAGGCCGA GTCCCGTGCG GAGGCAGCCC GGATTGAGGG AGAAGGGTCC 
GTGCTGCAGG CCAAGCTAAA AGCACAGGCC TTGGCCATTG AAACGGAGGC TGAGCTCCAG 
AGGGTCCAGA AGGTCCGAGA GCTGGAACTG GTCTATGCCC GGGCCCAGCT GGAGCTGGAG 
GTGAGCAAGG CTCAGCAGCT GGCTGAGGTG GAGGTGAAGA AGTTCAAGCA GATGACAGAG 
GCCATAGGCC CCAGCACCAT CAGGGACCTT GCTGTGGCTG GGCCTGAGAT GCAGGTAAAA 
CTGCTCCAGT CCCTGGGCCT GAAATCAACC CTCATCACCG ATGGCTCCAC TCCCATCAAC 
CTCTTCAACA CAGCCTTTGG GCTGCTGGGG ATGGGGCCCG AGGGTCAGCC CCTGGGCAGA 
AGGGTGGCCA GTGGGCCCAG CCCTGGGGAG GGGATATCCC CCCAGTCTGC TCAGGCCCCT 
CAAGCTCCTG GAGACAACCA CGTGGTGCCT GTACTGCGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MVP ( NM_005115.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005106.2 Homo sapiens major vault protein (MVP), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu27810
Clone ID Related Accession (Same CDS sequence)	NM_017458.3 , NM_005115.4 , NM_005115.5
Accession Version	NM_005115.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2682bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	major vault protein isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA940597.1, BQ932800.1, BC015623.2 and BM999583.1. On Nov 19, 2010 this sequence version replaced NM_005115.3. Transcript Variant: This variant (2, also known as S-MVP) uses a different splice site in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.103392.1, SRR1803615.165093.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGCAACTG AAGAGTTCAT CATCCGCATC CCCCCATACC ACTATATCCA TGTGCTGGAC 
CAGAACAGCA ACGTGTCCCG TGTGGAGGTC GGGCCAAAGA CCTACATCCG GCAGGACAAT 
GAGAGGGTAC TGTTTGCCCC CATGCGCATG GTGACCGTCC CCCCACGTCA CTACTGCACA 
GTGGCCAACC CTGTGTCTCG GGATGCCCAG GGCTTGGTGC TGTTTGATGT CACAGGGCAA 
GTTCGGCTTC GCCACGCTGA CCTCGAGATC CGGCTGGCCC AGGACCCCTT CCCCCTGTAC 
CCAGGGGAGG TGCTGGAAAA GGACATCACA CCCCTGCAGG TGGTTCTGCC CAACACTGCC 
CTCCATCTAA AGGCGCTGCT TGATTTTGAG GATAAAGATG GAGACAAGGT GGTGGCAGGA 
GATGAGTGGC TTTTCGAGGG ACCTGGCACG TACATCCCCC GGAAGGAAGT GGAGGTCGTG 
GAGATCATTC AGGCCACCAT CATCAGGCAG AACCAGGCTC TGCGGCTCAG GGCCCGCAAG 
GAGTGCTGGG ACCGGGACGG CAAGGAGAGG GTGACAGGGG AAGAATGGCT GGTCACCACA 
GTAGGGGCGT ACCTCCCAGC GGTGTTTGAG GAGGTTCTGG ATTTGGTGGA CGCCGTCATC 
CTTACGGAAA AGACAGCCCT GCACCTCCGG GCTCGGCGGA ACTTCCGGGA CTTCAGGGGA 
GTGTCCCGCC GCACTGGGGA GGAGTGGCTG GTAACAGTGC AGGACACAGA GGCCCACGTG 
CCAGATGTCC ACGAGGAGGT GCTGGGGGTT GTGCCCATCA CCACCCTGGG CCCCCACAAC 
TACTGCGTGA TTCTCGACCC TGTCGGACCG GATGGCAAGA ATCAGCTGGG GCAGAAGCGC 
GTGGTCAAGG GAGAGAAGTC TTTTTTCCTC CAGCCAGGAG AGCAGCTGGA ACAAGGCATC 
CAGGATGTGT ATGTGCTGTC GGAGCAGCAG GGGCTGCTGC TGAGGGCCCT GCAGCCCCTG 
GAGGAGGGGG AGGATGAGGA GAAGGTCTCA CACCAGGCTG GGGACCACTG GCTCATCCGC 
GGACCCCTGG AGTATGTGCC ATCTGCCAAA GTGGAGGTGG TGGAGGAGCG CCAGGCCATC 
CCTCTAGACG AGAACGAGGG CATCTATGTG CAGGATGTCA AGACCGGAAA GGTGCGCGCT 
GTGATTGGAA GCACCTACAT GCTGACCCAG GACGAAGTCC TGTGGGAGAA AGAGCTGCCT 
CCCGGGGTGG AGGAGCTGCT GAACAAGGGG CAGGACCCTC TGGCAGACAG GGGTGAGAAG 
GACACAGCTA AGAGCCTCCA GCCCTTGGCG CCCCGGAACA AGACCCGTGT GGTCAGCTAC 
CGCGTGCCCC ACAACGCTGC GGTGCAGGTG TACGACTACC GAGAGAAGCG AGCCCGCGTG 
GTCTTCGGGC CTGAGCTGGT GTCGCTGGGT CCTGAGGAGC AGTTCACAGT GTTGTCCCTC 
TCAGCTGGGC GGCCCAAGCG TCCCCATGCC CGCCGTGCGC TCTGCCTGCT GCTGGGGCCT 
GACTTCTTCA CAGACGTCAT CACCATCGAA ACGGCGGATC ATGCCAGGCT GCAACTGCAG 
CTGGCCTACA ACTGGCACTT TGAGGTGAAT GACCGGAAGG ACCCCCAAGA GACGGCCAAG 
CTCTTTTCAG TGCCAGACTT TGTAGGTGAT GCCTGCAAAG CCATCGCATC CCGGGTGCGG 
GGGGCCGTGG CCTCTGTCAC TTTCGATGAC TTCCATAAGA ACTCAGCCCG CATCATTCGC 
ACTGCTGTCT TTGGCTTTGA GACCTCGGAA GCGAAGGGCC CCGATGGCAT GGCCCTGCCC 
AGGCCCCGGG ACCAGGCTGT CTTCCCCCAA AACGGGCTGG TGGTCAGCAG TGTGGACGTG 
CAGTCAGTGG AGCCTGTGGA TCAGAGGACC CGGGACGCCC TGCAACGCAG CGTCCAGCTG 
GCCATCGAGA TCACCACCAA CTCCCAGGAA GCGGCGGCCA AGCATGAGGC TCAGAGACTG 
GAGCAGGAAG CCCGCGGCCG GCTTGAGCGG CAGAAGATCC TGGACCAGTC AGAAGCCGAG 
AAAGCTCGCA AGGAACTTTT GGAGCTGGAG GCTCTGAGCA TGGCCGTGGA GAGCACCGGG 
ACTGCCAAGG CGGAGGCCGA GTCCCGTGCG GAGGCAGCCC GGATTGAGGG AGAAGGGTCC 
GTGCTGCAGG CCAAGCTAAA AGCACAGGCC TTGGCCATTG AAACGGAGGC TGAGCTCCAG 
AGGGTCCAGA AGGTCCGAGA GCTGGAACTG GTCTATGCCC GGGCCCAGCT GGAGCTGGAG 
GTGAGCAAGG CTCAGCAGCT GGCTGAGGTG GAGGTGAAGA AGTTCAAGCA GATGACAGAG 
GCCATAGGCC CCAGCACCAT CAGGGACCTT GCTGTGGCTG GGCCTGAGAT GCAGGTAAAA 
CTGCTCCAGT CCCTGGGCCT GAAATCAACC CTCATCACCG ATGGCTCCAC TCCCATCAAC 
CTCTTCAACA CAGCCTTTGG GCTGCTGGGG ATGGGGCCCG AGGGTCAGCC CCTGGGCAGA 
AGGGTGGCCA GTGGGCCCAG CCCTGGGGAG GGGATATCCC CCCAGTCTGC TCAGGCCCCT 
CAAGCTCCTG GAGACAACCA CGTGGTGCCT GTACTGCGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005106.2
CDS	153..2834
Translation	MATEEFIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPMRMVTVPPRHYCTVANPVSRDAQGLVLFDVTGQVRLRHADLEIRLAQDPFPLYPGEVLEKDITPLQVVLPNTALHLKALLDFEDKDGDKVVAGDEWLFEGPGTYIPRKEVEVVEIIQATIIRQNQALRLRARKECWDRDGKERVTGEEWLVTTVGAYLPAVFEEVLDLVDAVILTEKTALHLRARRNFRDFRGVSRRTGEEWLVTVQDTEAHVPDVHEEVLGVVPITTLGPHNYCVILDPVGPDGKNQLGQKRVVKGEKSFFLQPGEQLEQGIQDVYVLSEQQGLLLRALQPLEEGEDEEKVSHQAGDHWLIRGPLEYVPSAKVEVVEERQAIPLDENEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELPPGVEELLNKGQDPLADRGEKDTAKSLQPLAPRNKTRVVSYRVPHNAAVQVYDYREKRARVVFGPELVSLGPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQLAYNWHFEVNDRKDPQETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIRTAVFGFETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSTPINLFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAPQAPGDNHVVPVLR

Target ORF information:

RefSeq Version	NM_005115.4
Organism	Homo sapiens(human)
Definition	Homo sapiens major vault protein (MVP), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005115.4

ORF Insert Sequence:

ATGGCAACTG AAGAGTTCAT CATCCGCATC CCCCCATACC ACTATATCCA TGTGCTGGAC 
CAGAACAGCA ACGTGTCCCG TGTGGAGGTC GGGCCAAAGA CCTACATCCG GCAGGACAAT 
GAGAGGGTAC TGTTTGCCCC CATGCGCATG GTGACCGTCC CCCCACGTCA CTACTGCACA 
GTGGCCAACC CTGTGTCTCG GGATGCCCAG GGCTTGGTGC TGTTTGATGT CACAGGGCAA 
GTTCGGCTTC GCCACGCTGA CCTCGAGATC CGGCTGGCCC AGGACCCCTT CCCCCTGTAC 
CCAGGGGAGG TGCTGGAAAA GGACATCACA CCCCTGCAGG TGGTTCTGCC CAACACTGCC 
CTCCATCTAA AGGCGCTGCT TGATTTTGAG GATAAAGATG GAGACAAGGT GGTGGCAGGA 
GATGAGTGGC TTTTCGAGGG ACCTGGCACG TACATCCCCC GGAAGGAAGT GGAGGTCGTG 
GAGATCATTC AGGCCACCAT CATCAGGCAG AACCAGGCTC TGCGGCTCAG GGCCCGCAAG 
GAGTGCTGGG ACCGGGACGG CAAGGAGAGG GTGACAGGGG AAGAATGGCT GGTCACCACA 
GTAGGGGCGT ACCTCCCAGC GGTGTTTGAG GAGGTTCTGG ATTTGGTGGA CGCCGTCATC 
CTTACGGAAA AGACAGCCCT GCACCTCCGG GCTCGGCGGA ACTTCCGGGA CTTCAGGGGA 
GTGTCCCGCC GCACTGGGGA GGAGTGGCTG GTAACAGTGC AGGACACAGA GGCCCACGTG 
CCAGATGTCC ACGAGGAGGT GCTGGGGGTT GTGCCCATCA CCACCCTGGG CCCCCACAAC 
TACTGCGTGA TTCTCGACCC TGTCGGACCG GATGGCAAGA ATCAGCTGGG GCAGAAGCGC 
GTGGTCAAGG GAGAGAAGTC TTTTTTCCTC CAGCCAGGAG AGCAGCTGGA ACAAGGCATC 
CAGGATGTGT ATGTGCTGTC GGAGCAGCAG GGGCTGCTGC TGAGGGCCCT GCAGCCCCTG 
GAGGAGGGGG AGGATGAGGA GAAGGTCTCA CACCAGGCTG GGGACCACTG GCTCATCCGC 
GGACCCCTGG AGTATGTGCC ATCTGCCAAA GTGGAGGTGG TGGAGGAGCG CCAGGCCATC 
CCTCTAGACG AGAACGAGGG CATCTATGTG CAGGATGTCA AGACCGGAAA GGTGCGCGCT 
GTGATTGGAA GCACCTACAT GCTGACCCAG GACGAAGTCC TGTGGGAGAA AGAGCTGCCT 
CCCGGGGTGG AGGAGCTGCT GAACAAGGGG CAGGACCCTC TGGCAGACAG GGGTGAGAAG 
GACACAGCTA AGAGCCTCCA GCCCTTGGCG CCCCGGAACA AGACCCGTGT GGTCAGCTAC 
CGCGTGCCCC ACAACGCTGC GGTGCAGGTG TACGACTACC GAGAGAAGCG AGCCCGCGTG 
GTCTTCGGGC CTGAGCTGGT GTCGCTGGGT CCTGAGGAGC AGTTCACAGT GTTGTCCCTC 
TCAGCTGGGC GGCCCAAGCG TCCCCATGCC CGCCGTGCGC TCTGCCTGCT GCTGGGGCCT 
GACTTCTTCA CAGACGTCAT CACCATCGAA ACGGCGGATC ATGCCAGGCT GCAACTGCAG 
CTGGCCTACA ACTGGCACTT TGAGGTGAAT GACCGGAAGG ACCCCCAAGA GACGGCCAAG 
CTCTTTTCAG TGCCAGACTT TGTAGGTGAT GCCTGCAAAG CCATCGCATC CCGGGTGCGG 
GGGGCCGTGG CCTCTGTCAC TTTCGATGAC TTCCATAAGA ACTCAGCCCG CATCATTCGC 
ACTGCTGTCT TTGGCTTTGA GACCTCGGAA GCGAAGGGCC CCGATGGCAT GGCCCTGCCC 
AGGCCCCGGG ACCAGGCTGT CTTCCCCCAA AACGGGCTGG TGGTCAGCAG TGTGGACGTG 
CAGTCAGTGG AGCCTGTGGA TCAGAGGACC CGGGACGCCC TGCAACGCAG CGTCCAGCTG 
GCCATCGAGA TCACCACCAA CTCCCAGGAA GCGGCGGCCA AGCATGAGGC TCAGAGACTG 
GAGCAGGAAG CCCGCGGCCG GCTTGAGCGG CAGAAGATCC TGGACCAGTC AGAAGCCGAG 
AAAGCTCGCA AGGAACTTTT GGAGCTGGAG GCTCTGAGCA TGGCCGTGGA GAGCACCGGG 
ACTGCCAAGG CGGAGGCCGA GTCCCGTGCG GAGGCAGCCC GGATTGAGGG AGAAGGGTCC 
GTGCTGCAGG CCAAGCTAAA AGCACAGGCC TTGGCCATTG AAACGGAGGC TGAGCTCCAG 
AGGGTCCAGA AGGTCCGAGA GCTGGAACTG GTCTATGCCC GGGCCCAGCT GGAGCTGGAG 
GTGAGCAAGG CTCAGCAGCT GGCTGAGGTG GAGGTGAAGA AGTTCAAGCA GATGACAGAG 
GCCATAGGCC CCAGCACCAT CAGGGACCTT GCTGTGGCTG GGCCTGAGAT GCAGGTAAAA 
CTGCTCCAGT CCCTGGGCCT GAAATCAACC CTCATCACCG ATGGCTCCAC TCCCATCAAC 
CTCTTCAACA CAGCCTTTGG GCTGCTGGGG ATGGGGCCCG AGGGTCAGCC CCTGGGCAGA 
AGGGTGGCCA GTGGGCCCAG CCCTGGGGAG GGGATATCCC CCCAGTCTGC TCAGGCCCCT 
CAAGCTCCTG GAGACAACCA CGTGGTGCCT GTACTGCGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MVP ( NM_005115.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_005106.2 Homo sapiens major vault protein (MVP), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu27810
Clone ID Related Accession (Same CDS sequence)	NM_017458.3 , NM_005115.4 , NM_005115.5
Accession Version	NM_005115.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2682bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	major vault protein isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA940597.1, BQ932800.1, BC015623.2 and BM999583.1. On Nov 23, 2018 this sequence version replaced NM_005115.4. Transcript Variant: This variant (2, also known as S-MVP) uses a different splice site in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: HM005570.1, SRR1803617.77162.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000357402.10/ ENSP00000349977.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCAACTG AAGAGTTCAT CATCCGCATC CCCCCATACC ACTATATCCA TGTGCTGGAC 
CAGAACAGCA ACGTGTCCCG TGTGGAGGTC GGGCCAAAGA CCTACATCCG GCAGGACAAT 
GAGAGGGTAC TGTTTGCCCC CATGCGCATG GTGACCGTCC CCCCACGTCA CTACTGCACA 
GTGGCCAACC CTGTGTCTCG GGATGCCCAG GGCTTGGTGC TGTTTGATGT CACAGGGCAA 
GTTCGGCTTC GCCACGCTGA CCTCGAGATC CGGCTGGCCC AGGACCCCTT CCCCCTGTAC 
CCAGGGGAGG TGCTGGAAAA GGACATCACA CCCCTGCAGG TGGTTCTGCC CAACACTGCC 
CTCCATCTAA AGGCGCTGCT TGATTTTGAG GATAAAGATG GAGACAAGGT GGTGGCAGGA 
GATGAGTGGC TTTTCGAGGG ACCTGGCACG TACATCCCCC GGAAGGAAGT GGAGGTCGTG 
GAGATCATTC AGGCCACCAT CATCAGGCAG AACCAGGCTC TGCGGCTCAG GGCCCGCAAG 
GAGTGCTGGG ACCGGGACGG CAAGGAGAGG GTGACAGGGG AAGAATGGCT GGTCACCACA 
GTAGGGGCGT ACCTCCCAGC GGTGTTTGAG GAGGTTCTGG ATTTGGTGGA CGCCGTCATC 
CTTACGGAAA AGACAGCCCT GCACCTCCGG GCTCGGCGGA ACTTCCGGGA CTTCAGGGGA 
GTGTCCCGCC GCACTGGGGA GGAGTGGCTG GTAACAGTGC AGGACACAGA GGCCCACGTG 
CCAGATGTCC ACGAGGAGGT GCTGGGGGTT GTGCCCATCA CCACCCTGGG CCCCCACAAC 
TACTGCGTGA TTCTCGACCC TGTCGGACCG GATGGCAAGA ATCAGCTGGG GCAGAAGCGC 
GTGGTCAAGG GAGAGAAGTC TTTTTTCCTC CAGCCAGGAG AGCAGCTGGA ACAAGGCATC 
CAGGATGTGT ATGTGCTGTC GGAGCAGCAG GGGCTGCTGC TGAGGGCCCT GCAGCCCCTG 
GAGGAGGGGG AGGATGAGGA GAAGGTCTCA CACCAGGCTG GGGACCACTG GCTCATCCGC 
GGACCCCTGG AGTATGTGCC ATCTGCCAAA GTGGAGGTGG TGGAGGAGCG CCAGGCCATC 
CCTCTAGACG AGAACGAGGG CATCTATGTG CAGGATGTCA AGACCGGAAA GGTGCGCGCT 
GTGATTGGAA GCACCTACAT GCTGACCCAG GACGAAGTCC TGTGGGAGAA AGAGCTGCCT 
CCCGGGGTGG AGGAGCTGCT GAACAAGGGG CAGGACCCTC TGGCAGACAG GGGTGAGAAG 
GACACAGCTA AGAGCCTCCA GCCCTTGGCG CCCCGGAACA AGACCCGTGT GGTCAGCTAC 
CGCGTGCCCC ACAACGCTGC GGTGCAGGTG TACGACTACC GAGAGAAGCG AGCCCGCGTG 
GTCTTCGGGC CTGAGCTGGT GTCGCTGGGT CCTGAGGAGC AGTTCACAGT GTTGTCCCTC 
TCAGCTGGGC GGCCCAAGCG TCCCCATGCC CGCCGTGCGC TCTGCCTGCT GCTGGGGCCT 
GACTTCTTCA CAGACGTCAT CACCATCGAA ACGGCGGATC ATGCCAGGCT GCAACTGCAG 
CTGGCCTACA ACTGGCACTT TGAGGTGAAT GACCGGAAGG ACCCCCAAGA GACGGCCAAG 
CTCTTTTCAG TGCCAGACTT TGTAGGTGAT GCCTGCAAAG CCATCGCATC CCGGGTGCGG 
GGGGCCGTGG CCTCTGTCAC TTTCGATGAC TTCCATAAGA ACTCAGCCCG CATCATTCGC 
ACTGCTGTCT TTGGCTTTGA GACCTCGGAA GCGAAGGGCC CCGATGGCAT GGCCCTGCCC 
AGGCCCCGGG ACCAGGCTGT CTTCCCCCAA AACGGGCTGG TGGTCAGCAG TGTGGACGTG 
CAGTCAGTGG AGCCTGTGGA TCAGAGGACC CGGGACGCCC TGCAACGCAG CGTCCAGCTG 
GCCATCGAGA TCACCACCAA CTCCCAGGAA GCGGCGGCCA AGCATGAGGC TCAGAGACTG 
GAGCAGGAAG CCCGCGGCCG GCTTGAGCGG CAGAAGATCC TGGACCAGTC AGAAGCCGAG 
AAAGCTCGCA AGGAACTTTT GGAGCTGGAG GCTCTGAGCA TGGCCGTGGA GAGCACCGGG 
ACTGCCAAGG CGGAGGCCGA GTCCCGTGCG GAGGCAGCCC GGATTGAGGG AGAAGGGTCC 
GTGCTGCAGG CCAAGCTAAA AGCACAGGCC TTGGCCATTG AAACGGAGGC TGAGCTCCAG 
AGGGTCCAGA AGGTCCGAGA GCTGGAACTG GTCTATGCCC GGGCCCAGCT GGAGCTGGAG 
GTGAGCAAGG CTCAGCAGCT GGCTGAGGTG GAGGTGAAGA AGTTCAAGCA GATGACAGAG 
GCCATAGGCC CCAGCACCAT CAGGGACCTT GCTGTGGCTG GGCCTGAGAT GCAGGTAAAA 
CTGCTCCAGT CCCTGGGCCT GAAATCAACC CTCATCACCG ATGGCTCCAC TCCCATCAAC 
CTCTTCAACA CAGCCTTTGG GCTGCTGGGG ATGGGGCCCG AGGGTCAGCC CCTGGGCAGA 
AGGGTGGCCA GTGGGCCCAG CCCTGGGGAG GGGATATCCC CCCAGTCTGC TCAGGCCCCT 
CAAGCTCCTG GAGACAACCA CGTGGTGCCT GTACTGCGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005106.2
CDS	85..2766
Translation	MATEEFIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPMRMVTVPPRHYCTVANPVSRDAQGLVLFDVTGQVRLRHADLEIRLAQDPFPLYPGEVLEKDITPLQVVLPNTALHLKALLDFEDKDGDKVVAGDEWLFEGPGTYIPRKEVEVVEIIQATIIRQNQALRLRARKECWDRDGKERVTGEEWLVTTVGAYLPAVFEEVLDLVDAVILTEKTALHLRARRNFRDFRGVSRRTGEEWLVTVQDTEAHVPDVHEEVLGVVPITTLGPHNYCVILDPVGPDGKNQLGQKRVVKGEKSFFLQPGEQLEQGIQDVYVLSEQQGLLLRALQPLEEGEDEEKVSHQAGDHWLIRGPLEYVPSAKVEVVEERQAIPLDENEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELPPGVEELLNKGQDPLADRGEKDTAKSLQPLAPRNKTRVVSYRVPHNAAVQVYDYREKRARVVFGPELVSLGPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQLAYNWHFEVNDRKDPQETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIRTAVFGFETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSTPINLFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAPQAPGDNHVVPVLR

Target ORF information:

RefSeq Version	NM_005115.5
Organism	Homo sapiens(human)
Definition	Homo sapiens major vault protein (MVP), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005115.5

ORF Insert Sequence:

ATGGCAACTG AAGAGTTCAT CATCCGCATC CCCCCATACC ACTATATCCA TGTGCTGGAC 
CAGAACAGCA ACGTGTCCCG TGTGGAGGTC GGGCCAAAGA CCTACATCCG GCAGGACAAT 
GAGAGGGTAC TGTTTGCCCC CATGCGCATG GTGACCGTCC CCCCACGTCA CTACTGCACA 
GTGGCCAACC CTGTGTCTCG GGATGCCCAG GGCTTGGTGC TGTTTGATGT CACAGGGCAA 
GTTCGGCTTC GCCACGCTGA CCTCGAGATC CGGCTGGCCC AGGACCCCTT CCCCCTGTAC 
CCAGGGGAGG TGCTGGAAAA GGACATCACA CCCCTGCAGG TGGTTCTGCC CAACACTGCC 
CTCCATCTAA AGGCGCTGCT TGATTTTGAG GATAAAGATG GAGACAAGGT GGTGGCAGGA 
GATGAGTGGC TTTTCGAGGG ACCTGGCACG TACATCCCCC GGAAGGAAGT GGAGGTCGTG 
GAGATCATTC AGGCCACCAT CATCAGGCAG AACCAGGCTC TGCGGCTCAG GGCCCGCAAG 
GAGTGCTGGG ACCGGGACGG CAAGGAGAGG GTGACAGGGG AAGAATGGCT GGTCACCACA 
GTAGGGGCGT ACCTCCCAGC GGTGTTTGAG GAGGTTCTGG ATTTGGTGGA CGCCGTCATC 
CTTACGGAAA AGACAGCCCT GCACCTCCGG GCTCGGCGGA ACTTCCGGGA CTTCAGGGGA 
GTGTCCCGCC GCACTGGGGA GGAGTGGCTG GTAACAGTGC AGGACACAGA GGCCCACGTG 
CCAGATGTCC ACGAGGAGGT GCTGGGGGTT GTGCCCATCA CCACCCTGGG CCCCCACAAC 
TACTGCGTGA TTCTCGACCC TGTCGGACCG GATGGCAAGA ATCAGCTGGG GCAGAAGCGC 
GTGGTCAAGG GAGAGAAGTC TTTTTTCCTC CAGCCAGGAG AGCAGCTGGA ACAAGGCATC 
CAGGATGTGT ATGTGCTGTC GGAGCAGCAG GGGCTGCTGC TGAGGGCCCT GCAGCCCCTG 
GAGGAGGGGG AGGATGAGGA GAAGGTCTCA CACCAGGCTG GGGACCACTG GCTCATCCGC 
GGACCCCTGG AGTATGTGCC ATCTGCCAAA GTGGAGGTGG TGGAGGAGCG CCAGGCCATC 
CCTCTAGACG AGAACGAGGG CATCTATGTG CAGGATGTCA AGACCGGAAA GGTGCGCGCT 
GTGATTGGAA GCACCTACAT GCTGACCCAG GACGAAGTCC TGTGGGAGAA AGAGCTGCCT 
CCCGGGGTGG AGGAGCTGCT GAACAAGGGG CAGGACCCTC TGGCAGACAG GGGTGAGAAG 
GACACAGCTA AGAGCCTCCA GCCCTTGGCG CCCCGGAACA AGACCCGTGT GGTCAGCTAC 
CGCGTGCCCC ACAACGCTGC GGTGCAGGTG TACGACTACC GAGAGAAGCG AGCCCGCGTG 
GTCTTCGGGC CTGAGCTGGT GTCGCTGGGT CCTGAGGAGC AGTTCACAGT GTTGTCCCTC 
TCAGCTGGGC GGCCCAAGCG TCCCCATGCC CGCCGTGCGC TCTGCCTGCT GCTGGGGCCT 
GACTTCTTCA CAGACGTCAT CACCATCGAA ACGGCGGATC ATGCCAGGCT GCAACTGCAG 
CTGGCCTACA ACTGGCACTT TGAGGTGAAT GACCGGAAGG ACCCCCAAGA GACGGCCAAG 
CTCTTTTCAG TGCCAGACTT TGTAGGTGAT GCCTGCAAAG CCATCGCATC CCGGGTGCGG 
GGGGCCGTGG CCTCTGTCAC TTTCGATGAC TTCCATAAGA ACTCAGCCCG CATCATTCGC 
ACTGCTGTCT TTGGCTTTGA GACCTCGGAA GCGAAGGGCC CCGATGGCAT GGCCCTGCCC 
AGGCCCCGGG ACCAGGCTGT CTTCCCCCAA AACGGGCTGG TGGTCAGCAG TGTGGACGTG 
CAGTCAGTGG AGCCTGTGGA TCAGAGGACC CGGGACGCCC TGCAACGCAG CGTCCAGCTG 
GCCATCGAGA TCACCACCAA CTCCCAGGAA GCGGCGGCCA AGCATGAGGC TCAGAGACTG 
GAGCAGGAAG CCCGCGGCCG GCTTGAGCGG CAGAAGATCC TGGACCAGTC AGAAGCCGAG 
AAAGCTCGCA AGGAACTTTT GGAGCTGGAG GCTCTGAGCA TGGCCGTGGA GAGCACCGGG 
ACTGCCAAGG CGGAGGCCGA GTCCCGTGCG GAGGCAGCCC GGATTGAGGG AGAAGGGTCC 
GTGCTGCAGG CCAAGCTAAA AGCACAGGCC TTGGCCATTG AAACGGAGGC TGAGCTCCAG 
AGGGTCCAGA AGGTCCGAGA GCTGGAACTG GTCTATGCCC GGGCCCAGCT GGAGCTGGAG 
GTGAGCAAGG CTCAGCAGCT GGCTGAGGTG GAGGTGAAGA AGTTCAAGCA GATGACAGAG 
GCCATAGGCC CCAGCACCAT CAGGGACCTT GCTGTGGCTG GGCCTGAGAT GCAGGTAAAA 
CTGCTCCAGT CCCTGGGCCT GAAATCAACC CTCATCACCG ATGGCTCCAC TCCCATCAAC 
CTCTTCAACA CAGCCTTTGG GCTGCTGGGG ATGGGGCCCG AGGGTCAGCC CCTGGGCAGA 
AGGGTGGCCA GTGGGCCCAG CCCTGGGGAG GGGATATCCC CCCAGTCTGC TCAGGCCCCT 
CAAGCTCCTG GAGACAACCA CGTGGTGCCT GTACTGCGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MVP ( NM_001293204.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001280133.1 Homo sapiens major vault protein (MVP), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu27819
Clone ID Related Accession (Same CDS sequence)	NM_001293204.1
Accession Version	NM_001293204.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2502bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-13
Organism	Homo sapiens(human)
Product	major vault protein isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ291366.1, KJ534886.1 and BM999583.1. Transcript Variant: This variant (3) has an alternate in-frame splice junction in the 3' coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: KJ534886.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGCAACTG AAGAGTTCAT CATCCGCATC CCCCCATACC ACTATATCCA TGTGCTGGAC 
CAGAACAGCA ACGTGTCCCG TGTGGAGGTC GGGCCAAAGA CCTACATCCG GCAGGACAAT 
GAGAGGGTAC TGTTTGCCCC CATGCGCATG GTGACCGTCC CCCCACGTCA CTACTGCACA 
GTGGCCAACC CTGTGTCTCG GGATGCCCAG GGCTTGGTGC TGTTTGATGT CACAGGGCAA 
GTTCGGCTTC GCCACGCTGA CCTCGAGATC CGGCTGGCCC AGGACCCCTT CCCCCTGTAC 
CCAGGGGAGG TGCTGGAAAA GGACATCACA CCCCTGCAGG TGGTTCTGCC CAACACTGCC 
CTCCATCTAA AGGCGCTGCT TGATTTTGAG GATAAAGATG GAGACAAGGT GGTGGCAGGA 
GATGAGTGGC TTTTCGAGGG ACCTGGCACG TACATCCCCC GGAAGGAAGT GGAGGTCGTG 
GAGATCATTC AGGCCACCAT CATCAGGCAG AACCAGGCTC TGCGGCTCAG GGCCCGCAAG 
GAGTGCTGGG ACCGGGACGG CAAGGAGAGG GTGACAGGGG AAGAATGGCT GGTCACCACA 
GTAGGGGCGT ACCTCCCAGC GGTGTTTGAG GAGGTTCTGG ATTTGGTGGA CGCCGTCATC 
CTTACGGAAA AGACAGCCCT GCACCTCCGG GCTCGGCGGA ACTTCCGGGA CTTCAGGGGA 
GTGTCCCGCC GCACTGGGGA GGAGTGGCTG GTAACAGTGC AGGACACAGA GGCCCACGTG 
CCAGATGTCC ACGAGGAGGT GCTGGGGGTT GTGCCCATCA CCACCCTGGG CCCCCACAAC 
TACTGCGTGA TTCTCGACCC TGTCGGACCG GATGGCAAGA ATCAGCTGGG GCAGAAGCGC 
GTGGTCAAGG GAGAGAAGTC TTTTTTCCTC CAGCCAGGAG AGCAGCTGGA ACAAGGCATC 
CAGGATGTGT ATGTGCTGTC GGAGCAGCAG GGGCTGCTGC TGAGGGCCCT GCAGCCCCTG 
GAGGAGGGGG AGGATGAGGA GAAGGTCTCA CACCAGGCTG GGGACCACTG GCTCATCCGC 
GGACCCCTGG AGTATGTGCC ATCTGCCAAA GTGGAGGTGG TGGAGGAGCG CCAGGCCATC 
CCTCTAGACG AGAACGAGGG CATCTATGTG CAGGATGTCA AGACCGGAAA GGTGCGCGCT 
GTGATTGGAA GCACCTACAT GCTGACCCAG GACGAAGTCC TGTGGGAGAA AGAGCTGCCT 
CCCGGGGTGG AGGAGCTGCT GAACAAGGGG CAGGACCCTC TGGCAGACAG GGGTGAGAAG 
GACACAGCTA AGAGCCTCCA GCCCTTGGCG CCCCGGAACA AGACCCGTGT GGTCAGCTAC 
CGCGTGCCCC ACAACGCTGC GGTGCAGGTG TACGACTACC GAGAGAAGCG AGCCCGCGTG 
GTCTTCGGGC CTGAGCTGGT GTCGCTGGGT CCTGAGGAGC AGTTCACAGT GTTGTCCCTC 
TCAGCTGGGC GGCCCAAGCG TCCCCATGCC CGCCGTGCGC TCTGCCTGCT GCTGGGGCCT 
GACTTCTTCA CAGACGTCAT CACCATCGAA ACGGCGGATC ATGCCAGGCT GCAACTGCAG 
CTGGCCTACA ACTGGCACTT TGAGGTGAAT GACCGGAAGG ACCCCCAAGA GACGGCCAAG 
CTCTTTTCAG TGCCAGACTT TGTAGGTGAT GCCTGCAAAG CCATCGCATC CCGGGTGCGG 
GGGGCCGTGG CCTCTGTCAC TTTCGATGAC TTCCATAAGA ACTCAGCCCG CATCATTCGC 
ACTGCTGTCT TTGGCTTTGA GACCTCGGAA GCGAAGGGCC CCGATGGCAT GGCCCTGCCC 
AGGCCCCGGG ACCAGGCTGT CTTCCCCCAA AACGGGCTGG TGGTCAGCAG TGTGGACGTG 
CAGTCAGTGG AGCCTGTGGA TCAGAGGACC CGGGACGCCC TGCAACGCAG CGTCCAGCTG 
GCCATCGAGA TCACCACCAA CTCCCAGGAA GCGGCGGCCA AGCATGAGGC TCAGAGACTG 
GAGCAGGAAG CCCGCGGCCG GCTTGAGCGG CAGAAGATCC TGGACCAGTC AGAAGCCGAG 
AAAGCTCGCA AGGAACTTTT GGAGCTGGAG GCTCTGAGCA TGGCCGTGGA GAGCACCGGG 
ACTGCCAAGG CGGAGGCCGA GTCCCGTGCG GAGGCAGCCC GGATTGAGGG AGAAGGGTCC 
GTGCTGCAGG CCAACACCAT CAGGGACCTT GCTGTGGCTG GGCCTGAGAT GCAGGTAAAA 
CTGCTCCAGT CCCTGGGCCT GAAATCAACC CTCATCACCG ATGGCTCCAC TCCCATCAAC 
CTCTTCAACA CAGCCTTTGG GCTGCTGGGG ATGGGGCCCG AGGGTCAGCC CCTGGGCAGA 
AGGGTGGCCA GTGGGCCCAG CCCTGGGGAG GGGATATCCC CCCAGTCTGC TCAGGCCCCT 
CAAGCTCCTG GAGACAACCA CGTGGTGCCT GTACTGCGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001280133.1
CDS	36..2537
Translation	MATEEFIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPMRMVTVPPRHYCTVANPVSRDAQGLVLFDVTGQVRLRHADLEIRLAQDPFPLYPGEVLEKDITPLQVVLPNTALHLKALLDFEDKDGDKVVAGDEWLFEGPGTYIPRKEVEVVEIIQATIIRQNQALRLRARKECWDRDGKERVTGEEWLVTTVGAYLPAVFEEVLDLVDAVILTEKTALHLRARRNFRDFRGVSRRTGEEWLVTVQDTEAHVPDVHEEVLGVVPITTLGPHNYCVILDPVGPDGKNQLGQKRVVKGEKSFFLQPGEQLEQGIQDVYVLSEQQGLLLRALQPLEEGEDEEKVSHQAGDHWLIRGPLEYVPSAKVEVVEERQAIPLDENEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELPPGVEELLNKGQDPLADRGEKDTAKSLQPLAPRNKTRVVSYRVPHNAAVQVYDYREKRARVVFGPELVSLGPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQLAYNWHFEVNDRKDPQETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIRTAVFGFETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQANTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSTPINLFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAPQAPGDNHVVPVLR

Target ORF information:

RefSeq Version	NM_001293204.1
Organism	Homo sapiens(human)
Definition	Homo sapiens major vault protein (MVP), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001293204.1

ORF Insert Sequence:

ATGGCAACTG AAGAGTTCAT CATCCGCATC CCCCCATACC ACTATATCCA TGTGCTGGAC 
CAGAACAGCA ACGTGTCCCG TGTGGAGGTC GGGCCAAAGA CCTACATCCG GCAGGACAAT 
GAGAGGGTAC TGTTTGCCCC CATGCGCATG GTGACCGTCC CCCCACGTCA CTACTGCACA 
GTGGCCAACC CTGTGTCTCG GGATGCCCAG GGCTTGGTGC TGTTTGATGT CACAGGGCAA 
GTTCGGCTTC GCCACGCTGA CCTCGAGATC CGGCTGGCCC AGGACCCCTT CCCCCTGTAC 
CCAGGGGAGG TGCTGGAAAA GGACATCACA CCCCTGCAGG TGGTTCTGCC CAACACTGCC 
CTCCATCTAA AGGCGCTGCT TGATTTTGAG GATAAAGATG GAGACAAGGT GGTGGCAGGA 
GATGAGTGGC TTTTCGAGGG ACCTGGCACG TACATCCCCC GGAAGGAAGT GGAGGTCGTG 
GAGATCATTC AGGCCACCAT CATCAGGCAG AACCAGGCTC TGCGGCTCAG GGCCCGCAAG 
GAGTGCTGGG ACCGGGACGG CAAGGAGAGG GTGACAGGGG AAGAATGGCT GGTCACCACA 
GTAGGGGCGT ACCTCCCAGC GGTGTTTGAG GAGGTTCTGG ATTTGGTGGA CGCCGTCATC 
CTTACGGAAA AGACAGCCCT GCACCTCCGG GCTCGGCGGA ACTTCCGGGA CTTCAGGGGA 
GTGTCCCGCC GCACTGGGGA GGAGTGGCTG GTAACAGTGC AGGACACAGA GGCCCACGTG 
CCAGATGTCC ACGAGGAGGT GCTGGGGGTT GTGCCCATCA CCACCCTGGG CCCCCACAAC 
TACTGCGTGA TTCTCGACCC TGTCGGACCG GATGGCAAGA ATCAGCTGGG GCAGAAGCGC 
GTGGTCAAGG GAGAGAAGTC TTTTTTCCTC CAGCCAGGAG AGCAGCTGGA ACAAGGCATC 
CAGGATGTGT ATGTGCTGTC GGAGCAGCAG GGGCTGCTGC TGAGGGCCCT GCAGCCCCTG 
GAGGAGGGGG AGGATGAGGA GAAGGTCTCA CACCAGGCTG GGGACCACTG GCTCATCCGC 
GGACCCCTGG AGTATGTGCC ATCTGCCAAA GTGGAGGTGG TGGAGGAGCG CCAGGCCATC 
CCTCTAGACG AGAACGAGGG CATCTATGTG CAGGATGTCA AGACCGGAAA GGTGCGCGCT 
GTGATTGGAA GCACCTACAT GCTGACCCAG GACGAAGTCC TGTGGGAGAA AGAGCTGCCT 
CCCGGGGTGG AGGAGCTGCT GAACAAGGGG CAGGACCCTC TGGCAGACAG GGGTGAGAAG 
GACACAGCTA AGAGCCTCCA GCCCTTGGCG CCCCGGAACA AGACCCGTGT GGTCAGCTAC 
CGCGTGCCCC ACAACGCTGC GGTGCAGGTG TACGACTACC GAGAGAAGCG AGCCCGCGTG 
GTCTTCGGGC CTGAGCTGGT GTCGCTGGGT CCTGAGGAGC AGTTCACAGT GTTGTCCCTC 
TCAGCTGGGC GGCCCAAGCG TCCCCATGCC CGCCGTGCGC TCTGCCTGCT GCTGGGGCCT 
GACTTCTTCA CAGACGTCAT CACCATCGAA ACGGCGGATC ATGCCAGGCT GCAACTGCAG 
CTGGCCTACA ACTGGCACTT TGAGGTGAAT GACCGGAAGG ACCCCCAAGA GACGGCCAAG 
CTCTTTTCAG TGCCAGACTT TGTAGGTGAT GCCTGCAAAG CCATCGCATC CCGGGTGCGG 
GGGGCCGTGG CCTCTGTCAC TTTCGATGAC TTCCATAAGA ACTCAGCCCG CATCATTCGC 
ACTGCTGTCT TTGGCTTTGA GACCTCGGAA GCGAAGGGCC CCGATGGCAT GGCCCTGCCC 
AGGCCCCGGG ACCAGGCTGT CTTCCCCCAA AACGGGCTGG TGGTCAGCAG TGTGGACGTG 
CAGTCAGTGG AGCCTGTGGA TCAGAGGACC CGGGACGCCC TGCAACGCAG CGTCCAGCTG 
GCCATCGAGA TCACCACCAA CTCCCAGGAA GCGGCGGCCA AGCATGAGGC TCAGAGACTG 
GAGCAGGAAG CCCGCGGCCG GCTTGAGCGG CAGAAGATCC TGGACCAGTC AGAAGCCGAG 
AAAGCTCGCA AGGAACTTTT GGAGCTGGAG GCTCTGAGCA TGGCCGTGGA GAGCACCGGG 
ACTGCCAAGG CGGAGGCCGA GTCCCGTGCG GAGGCAGCCC GGATTGAGGG AGAAGGGTCC 
GTGCTGCAGG CCAACACCAT CAGGGACCTT GCTGTGGCTG GGCCTGAGAT GCAGGTAAAA 
CTGCTCCAGT CCCTGGGCCT GAAATCAACC CTCATCACCG ATGGCTCCAC TCCCATCAAC 
CTCTTCAACA CAGCCTTTGG GCTGCTGGGG ATGGGGCCCG AGGGTCAGCC CCTGGGCAGA 
AGGGTGGCCA GTGGGCCCAG CCCTGGGGAG GGGATATCCC CCCAGTCTGC TCAGGCCCCT 
CAAGCTCCTG GAGACAACCA CGTGGTGCCT GTACTGCGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MVP ( NM_001293205.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001280134.1 Homo sapiens major vault protein (MVP), transcript variant 4, mRNA.

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CloneID	OHu27821
Clone ID Related Accession (Same CDS sequence)	NM_001293205.1
Accession Version	NM_001293205.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2484bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-13
Organism	Homo sapiens(human)
Product	major vault protein isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ291366.1, KJ534885.1, BC015623.2 and BM999583.1. Transcript Variant: This variant (4) lacks an in-frame exon in the central coding region, compared to variant 1. The resulting isoform (3) lacks an internal segment, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: KJ534885.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGGCAACTG AAGAGTTCAT CATCCGCATC CCCCCATACC ACTATATCCA TGTGCTGGAC 
CAGAACAGCA ACGTGTCCCG TGTGGAGGTC GGGCCAAAGA CCTACATCCG GCAGGACAAT 
GAGAGGGTAC TGTTTGCCCC CATGCGCATG GTGACCGTCC CCCCACGTCA CTACTGCACA 
GTGGCCAACC CTGTGTCTCG GGATGCCCAG GGCTTGGTGC TGTTTGATGT CACAGGGCAA 
GTTCGGCTTC GCCACGCTGA CCTCGAGATC CGGCTGGCCC AGGACCCCTT CCCCCTGTAC 
CCAGGGGAGG TGCTGGAAAA GGACATCACA CCCCTGCAGG TGGTTCTGCC CAACACTGCC 
CTCCATCTAA AGGCGCTGCT TGATTTTGAG GATAAAGATG GAGACAAGGT GGTGGCAGGA 
GATGAGTGGC TTTTCGAGGG ACCTGGCACG TACATCCCCC GGAAGGAAGT GGAGGTCGTG 
GAGATCATTC AGGCCACCAT CATCAGGCAG AACCAGGCTC TGCGGCTCAG GGCCCGCAAG 
GAGTGCTGGG ACCGGGACGG CAAGGAGAGG GTGACAGGGG AAGAATGGCT GGTCACCACA 
GTAGGGGCGT ACCTCCCAGC GGTGTTTGAG GAGGTTCTGG ATTTGGTGGA CGCCGTCATC 
CTTACGGAAA AGACAGCCCT GCACCTCCGG GCTCGGCGGA ACTTCCGGGA CTTCAGGGGA 
GTGTCCCGCC GCACTGGGGA GGAGTGGCTG GTAACAGTGC AGGACACAGA GGCCCACGTG 
CCAGATGTCC ACGAGGAGGT GCTGGGGGTT GTGCCCATCA CCACCCTGGG CCCCCACAAC 
TACTGCGTGA TTCTCGACCC TGTCGGACCG GATGGCAAGA ATCAGCTGGG GCAGAAGCGC 
GTGGTCAAGG GAGAGAAGTC TTTTTTCCTC CAGCCAGGAG AGCAGCTGGA ACAAGGCATC 
CAGGATGTGT ATGTGCTGTC GGAGCAGCAG GGGCTGCTGC TGAGGGCCCT GCAGCCCCTG 
GAGGAGGGGG AGGATGAGGA GAAGGTCTCA CACCAGGCTG GGGACCACTG GCTCATCCGC 
GGACCCCTGG AGTATGTGCC ATCTGCCAAA GTGGAGGTGG TGGAGGAGCG CCAGGCCATC 
CCTCTAGACG AGAACGAGGG CATCTATGTG CAGGATGTCA AGACCGGAAA GGTGCGCGCT 
GTGATTGGAA GCACCTACAT GCTGACCCAG GACGAAGTCC TGTGGGAGAA AGAGCTGCCT 
CCCGGGGTGG AGGAGCTGCT GAACAAGGGG CAGGACCCTC TGGCAGACAG GGGTGAGAAG 
GACACAGCTA AGAGCCTCCA GCCCTTGGCG CCCCGGAACA AGACCCGTGT GGTCAGCTAC 
CGCGTGCCCC ACAACGCTGC GGTGCAGGTG TACGACTACC GAGAGAAGCG AGCCCGGCAC 
TTTGAGGTGA ATGACCGGAA GGACCCCCAA GAGACGGCCA AGCTCTTTTC AGTGCCAGAC 
TTTGTAGGTG ATGCCTGCAA AGCCATCGCA TCCCGGGTGC GGGGGGCCGT GGCCTCTGTC 
ACTTTCGATG ACTTCCATAA GAACTCAGCC CGCATCATTC GCACTGCTGT CTTTGGCTTT 
GAGACCTCGG AAGCGAAGGG CCCCGATGGC ATGGCCCTGC CCAGGCCCCG GGACCAGGCT 
GTCTTCCCCC AAAACGGGCT GGTGGTCAGC AGTGTGGACG TGCAGTCAGT GGAGCCTGTG 
GATCAGAGGA CCCGGGACGC CCTGCAACGC AGCGTCCAGC TGGCCATCGA GATCACCACC 
AACTCCCAGG AAGCGGCGGC CAAGCATGAG GCTCAGAGAC TGGAGCAGGA AGCCCGCGGC 
CGGCTTGAGC GGCAGAAGAT CCTGGACCAG TCAGAAGCCG AGAAAGCTCG CAAGGAACTT 
TTGGAGCTGG AGGCTCTGAG CATGGCCGTG GAGAGCACCG GGACTGCCAA GGCGGAGGCC 
GAGTCCCGTG CGGAGGCAGC CCGGATTGAG GGAGAAGGGT CCGTGCTGCA GGCCAAGCTA 
AAAGCACAGG CCTTGGCCAT TGAAACGGAG GCTGAGCTCC AGAGGGTCCA GAAGGTCCGA 
GAGCTGGAAC TGGTCTATGC CCGGGCCCAG CTGGAGCTGG AGGTGAGCAA GGCTCAGCAG 
CTGGCTGAGG TGGAGGTGAA GAAGTTCAAG CAGATGACAG AGGCCATAGG CCCCAGCACC 
ATCAGGGACC TTGCTGTGGC TGGGCCTGAG ATGCAGGTAA AACTGCTCCA GTCCCTGGGC 
CTGAAATCAA CCCTCATCAC CGATGGCTCC ACTCCCATCA ACCTCTTCAA CACAGCCTTT 
GGGCTGCTGG GGATGGGGCC CGAGGGTCAG CCCCTGGGCA GAAGGGTGGC CAGTGGGCCC 
AGCCCTGGGG AGGGGATATC CCCCCAGTCT GCTCAGGCCC CTCAAGCTCC TGGAGACAAC 
CACGTGGTGC CTGTACTGCG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001280134.1
CDS	36..2519
Translation	MATEEFIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPMRMVTVPPRHYCTVANPVSRDAQGLVLFDVTGQVRLRHADLEIRLAQDPFPLYPGEVLEKDITPLQVVLPNTALHLKALLDFEDKDGDKVVAGDEWLFEGPGTYIPRKEVEVVEIIQATIIRQNQALRLRARKECWDRDGKERVTGEEWLVTTVGAYLPAVFEEVLDLVDAVILTEKTALHLRARRNFRDFRGVSRRTGEEWLVTVQDTEAHVPDVHEEVLGVVPITTLGPHNYCVILDPVGPDGKNQLGQKRVVKGEKSFFLQPGEQLEQGIQDVYVLSEQQGLLLRALQPLEEGEDEEKVSHQAGDHWLIRGPLEYVPSAKVEVVEERQAIPLDENEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELPPGVEELLNKGQDPLADRGEKDTAKSLQPLAPRNKTRVVSYRVPHNAAVQVYDYREKRARHFEVNDRKDPQETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIRTAVFGFETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSTPINLFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAPQAPGDNHVVPVLR

Target ORF information:

RefSeq Version	NM_001293205.1
Organism	Homo sapiens(human)
Definition	Homo sapiens major vault protein (MVP), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001293205.1

ORF Insert Sequence:

ATGGCAACTG AAGAGTTCAT CATCCGCATC CCCCCATACC ACTATATCCA TGTGCTGGAC 
CAGAACAGCA ACGTGTCCCG TGTGGAGGTC GGGCCAAAGA CCTACATCCG GCAGGACAAT 
GAGAGGGTAC TGTTTGCCCC CATGCGCATG GTGACCGTCC CCCCACGTCA CTACTGCACA 
GTGGCCAACC CTGTGTCTCG GGATGCCCAG GGCTTGGTGC TGTTTGATGT CACAGGGCAA 
GTTCGGCTTC GCCACGCTGA CCTCGAGATC CGGCTGGCCC AGGACCCCTT CCCCCTGTAC 
CCAGGGGAGG TGCTGGAAAA GGACATCACA CCCCTGCAGG TGGTTCTGCC CAACACTGCC 
CTCCATCTAA AGGCGCTGCT TGATTTTGAG GATAAAGATG GAGACAAGGT GGTGGCAGGA 
GATGAGTGGC TTTTCGAGGG ACCTGGCACG TACATCCCCC GGAAGGAAGT GGAGGTCGTG 
GAGATCATTC AGGCCACCAT CATCAGGCAG AACCAGGCTC TGCGGCTCAG GGCCCGCAAG 
GAGTGCTGGG ACCGGGACGG CAAGGAGAGG GTGACAGGGG AAGAATGGCT GGTCACCACA 
GTAGGGGCGT ACCTCCCAGC GGTGTTTGAG GAGGTTCTGG ATTTGGTGGA CGCCGTCATC 
CTTACGGAAA AGACAGCCCT GCACCTCCGG GCTCGGCGGA ACTTCCGGGA CTTCAGGGGA 
GTGTCCCGCC GCACTGGGGA GGAGTGGCTG GTAACAGTGC AGGACACAGA GGCCCACGTG 
CCAGATGTCC ACGAGGAGGT GCTGGGGGTT GTGCCCATCA CCACCCTGGG CCCCCACAAC 
TACTGCGTGA TTCTCGACCC TGTCGGACCG GATGGCAAGA ATCAGCTGGG GCAGAAGCGC 
GTGGTCAAGG GAGAGAAGTC TTTTTTCCTC CAGCCAGGAG AGCAGCTGGA ACAAGGCATC 
CAGGATGTGT ATGTGCTGTC GGAGCAGCAG GGGCTGCTGC TGAGGGCCCT GCAGCCCCTG 
GAGGAGGGGG AGGATGAGGA GAAGGTCTCA CACCAGGCTG GGGACCACTG GCTCATCCGC 
GGACCCCTGG AGTATGTGCC ATCTGCCAAA GTGGAGGTGG TGGAGGAGCG CCAGGCCATC 
CCTCTAGACG AGAACGAGGG CATCTATGTG CAGGATGTCA AGACCGGAAA GGTGCGCGCT 
GTGATTGGAA GCACCTACAT GCTGACCCAG GACGAAGTCC TGTGGGAGAA AGAGCTGCCT 
CCCGGGGTGG AGGAGCTGCT GAACAAGGGG CAGGACCCTC TGGCAGACAG GGGTGAGAAG 
GACACAGCTA AGAGCCTCCA GCCCTTGGCG CCCCGGAACA AGACCCGTGT GGTCAGCTAC 
CGCGTGCCCC ACAACGCTGC GGTGCAGGTG TACGACTACC GAGAGAAGCG AGCCCGGCAC 
TTTGAGGTGA ATGACCGGAA GGACCCCCAA GAGACGGCCA AGCTCTTTTC AGTGCCAGAC 
TTTGTAGGTG ATGCCTGCAA AGCCATCGCA TCCCGGGTGC GGGGGGCCGT GGCCTCTGTC 
ACTTTCGATG ACTTCCATAA GAACTCAGCC CGCATCATTC GCACTGCTGT CTTTGGCTTT 
GAGACCTCGG AAGCGAAGGG CCCCGATGGC ATGGCCCTGC CCAGGCCCCG GGACCAGGCT 
GTCTTCCCCC AAAACGGGCT GGTGGTCAGC AGTGTGGACG TGCAGTCAGT GGAGCCTGTG 
GATCAGAGGA CCCGGGACGC CCTGCAACGC AGCGTCCAGC TGGCCATCGA GATCACCACC 
AACTCCCAGG AAGCGGCGGC CAAGCATGAG GCTCAGAGAC TGGAGCAGGA AGCCCGCGGC 
CGGCTTGAGC GGCAGAAGAT CCTGGACCAG TCAGAAGCCG AGAAAGCTCG CAAGGAACTT 
TTGGAGCTGG AGGCTCTGAG CATGGCCGTG GAGAGCACCG GGACTGCCAA GGCGGAGGCC 
GAGTCCCGTG CGGAGGCAGC CCGGATTGAG GGAGAAGGGT CCGTGCTGCA GGCCAAGCTA 
AAAGCACAGG CCTTGGCCAT TGAAACGGAG GCTGAGCTCC AGAGGGTCCA GAAGGTCCGA 
GAGCTGGAAC TGGTCTATGC CCGGGCCCAG CTGGAGCTGG AGGTGAGCAA GGCTCAGCAG 
CTGGCTGAGG TGGAGGTGAA GAAGTTCAAG CAGATGACAG AGGCCATAGG CCCCAGCACC 
ATCAGGGACC TTGCTGTGGC TGGGCCTGAG ATGCAGGTAA AACTGCTCCA GTCCCTGGGC 
CTGAAATCAA CCCTCATCAC CGATGGCTCC ACTCCCATCA ACCTCTTCAA CACAGCCTTT 
GGGCTGCTGG GGATGGGGCC CGAGGGTCAG CCCCTGGGCA GAAGGGTGGC CAGTGGGCCC 
AGCCCTGGGG AGGGGATATC CCCCCAGTCT GCTCAGGCCC CTCAAGCTCC TGGAGACAAC 
CACGTGGTGC CTGTACTGCG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

vPARP Adjusts MVP Expression in Drug-resistant Cell Lines in Conjunction with MDR Proteins.
Anticancer research37(6)3015-3023(2017 06)
Wojtowicz K,Januchowski R,Nowicki M,Zabel M

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MVP cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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